The alarmin IL-1α is a master cytokine in acute lung inflammation induced by silica micro- and nanoparticles

Particle and Fibre Toxicology

Volumn 11, Issue 1, 2014, Pages

  Rabolli, Virginie ^a   Badissi, Alami ^a   Devosse, Raynal ^a   Uwambayinema, Francine ^a   Yakoub, Yousof ^a   Palmai Pallag, Mihaly ^a   Lebrun, Astrid ^a   De Gussem, Valentin ^a   Couillin, Isabelle ^b   Ryffel, Bernard ^b   Marbaix, Etienne ^c   Lison, Dominique ^a   Huaux, François ^a  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^b UNIVERSITÉ D'ORLÉANS   (France)

^c DE DUVE INSTITUTE   (Belgium)

Author keywords

Alarmins; IL 1 family; Inflammasome; Inflammation; Nanoparticles; Neutrophils; Silica

Indexed keywords

CHEMOKINE RECEPTOR CXCR2; HIGH MOBILITY GROUP B1 PROTEIN; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 33; NANOMATERIAL; RECOMBINANT INTERLEUKIN 1ALPHA; RECOMBINANT INTERLEUKIN 1BETA; SILICA MICROPARTICLE; SILICA NANOPARTICLE; UNCLASSIFIED DRUG; AIR POLLUTANT; IL1B PROTEIN, MOUSE; MICROSPHERE; NANOPARTICLE; NEUTRALIZING ANTIBODY; SILICON DIOXIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DENDRITIC CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; IN VITRO STUDY; IN VIVO STUDY; LUNG ALVEOLUS MACROPHAGE; LUNG LAVAGE; MOUSE; NEUTROPHIL COUNT; NONHUMAN; PARTICLE SIZE; PNEUMONIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN LOCALIZATION; UPREGULATION; WESTERN BLOTTING; ADVERSE EFFECTS; AIR POLLUTANT; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; CELL CULTURE; CELL LINE; CHEMICALLY INDUCED; CHEMISTRY; COMPARATIVE STUDY; CYTOLOGY; DRUG EFFECTS; EXPOSURE; GENETICS; IMMUNOLOGY; KNOCKOUT MOUSE; LUNG; METABOLISM; NEUTROPHIL CHEMOTAXIS; PATHOLOGY; RESPIRATORY TRACT MUCOSA; SECRETION (PROCESS); TOXICITY; TOXICITY TESTING;

MUS;

AIR POLLUTANTS; ANIMALS; ANTIBODIES, NEUTRALIZING; CELL LINE; CELLS, CULTURED; FEMALE; INHALATION EXPOSURE; INTERLEUKIN-1ALPHA; INTERLEUKIN-1BETA; LUNG; MACROPHAGES, ALVEOLAR; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROSPHERES; NANOPARTICLES; NEUTROPHIL INFILTRATION; PARTICLE SIZE; PNEUMONIA; RESPIRATORY MUCOSA; SILICON DIOXIDE; TOXICITY TESTS, ACUTE;

EID: 84924260052     PISSN: 17438977     EISSN: 17438977     Source Type: Journal    
DOI: 10.1186/s12989-014-0069-x     Document Type: Article

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