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Volumn 51, Issue , 2011, Pages 267-288

Macrophages and tissue injury: Agents of defense or destruction?

Author keywords

cytokines; fibrosis; inflammation; liver; lung; RNS; ROS

Indexed keywords

1,2 DICHLOROBENZENE; ALCOHOL; ASBESTOS; BLEOMYCIN; CADMIUM; CARBON TETRACHLORIDE; CHEMOKINE; CYTOKINE; ENDOTOXIN; GALACTOSAMINE; LIPID; OZONE; PARACETAMOL; PHENOBARBITAL; PROTEINASE; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE; SILICON DIOXIDE; THIOACETAMIDE;

EID: 79951963634     PISSN: 03621642     EISSN: 15454304     Source Type: Book Series    
DOI: 10.1146/annurev.pharmtox.010909.105812     Document Type: Article
Times cited : (503)

References (186)
  • 2
    • 38549136572 scopus 로고    scopus 로고
    • Macrophage activation by endogenous danger signals
    • DOI 10.1002/path.2284
    • Zhang X, Mosser DM. 2008. Macrophage activation by endogenous danger signals. J. Pathol. 214:161-78 (Pubitemid 351160154)
    • (2008) Journal of Pathology , vol.214 , Issue.2 , pp. 161-178
    • Zhang, X.1    Mosser, D.M.2
  • 3
    • 57149108312 scopus 로고    scopus 로고
    • Identification and characterization of infiltrating macrophages in acetaminophen-induced liver injury
    • DOI 10.1189/jlb.0308173
    • Holt MP, Cheng L, Ju C. 2008. Identification and characterization of infiltrating macrophages in acetaminophen-induced liver injury. J. Leukoc. Biol. 84:1410-21 (Pubitemid 352774476)
    • (2008) Journal of Leukocyte Biology , vol.84 , Issue.6 , pp. 1410-1421
    • Holt, M.P.1    Cheng, L.2    Ju, C.3
  • 4
    • 43449131255 scopus 로고    scopus 로고
    • A novel mechanism for CCR4 in the regulation of macrophage activation in bleomycin-induced pulmonary fibrosis
    • DOI 10.2353/ajpath.2008.070832
    • Trujillo G, O'Connor EC, Kunkel SL, Hogaboam CM. 2008. A novel mechanism for CCR4 in the regulation of macrophage activation in bleomycin-induced pulmonary fibrosis. Am. J. Pathol. 172:1209-21 (Pubitemid 351671535)
    • (2008) American Journal of Pathology , vol.172 , Issue.5 , pp. 1209-1221
    • Trujillo, G.1    O'Connor, E.C.2    Kunkel, S.L.3    Hogaboam, C.M.4
  • 6
    • 0036242256 scopus 로고    scopus 로고
    • Role of CCR2 in macrophage migration into the liver during acetaminophen-induced hepatotoxicity in the mouse
    • DOI 10.1053/jhep.2002.33162
    • Dambach DM, Watson LM, Gray KR, Durham SK, Laskin DL. 2002. Role of CCR2 in macrophage migration into the liver during acetaminophen-induced hepatotoxicity in the mouse. Hepatology 35:1093-103 (Pubitemid 34454006)
    • (2002) Hepatology , vol.35 , Issue.5 , pp. 1093-1103
    • Dambach, D.M.1    Watson, L.M.2    Gray, K.R.3    Durham, S.K.4    Laskin, D.L.5
  • 7
    • 68949122649 scopus 로고    scopus 로고
    • Macrophages and inflammatory mediators in chemical toxicity: A battle of forces
    • Laskin DL. 2009. Macrophages and inflammatory mediators in chemical toxicity: a battle of forces. Chem. Res. Toxicol. 22:1376-85
    • (2009) Chem. Res. Toxicol. , vol.22 , pp. 1376-85
    • Laskin, D.L.1
  • 9
    • 56749174940 scopus 로고    scopus 로고
    • Exploring the full spectrum of macrophage activation
    • Mosser DM, Edwards JP. 2008. Exploring the full spectrum of macrophage activation. Nat. Rev. Immunol. 8:958-69
    • (2008) Nat. Rev. Immunol. , vol.8 , pp. 958-69
    • Mosser, D.M.1    Edwards, J.P.2
  • 10
    • 4344706372 scopus 로고    scopus 로고
    • Functional plasticity of macrophages: Reversible adaptation to changing microenvironments
    • DOI 10.1189/jlb.0504272
    • Stout RD, Suttles J. 2004. Functional plasticity of macrophages: reversible adaptation to changing mi-croenvironments. J. Leukoc. Biol. 76:509-13 (Pubitemid 39129080)
    • (2004) Journal of Leukocyte Biology , vol.76 , Issue.3 , pp. 509-513
    • Stout, R.D.1    Suttles, J.2
  • 11
    • 85012843739 scopus 로고    scopus 로고
    • Nonparenchymal cells, inflammatory macrophages, and hepatotoxicity
    • ed. N Kaplowitz, LD DeLeve New York: Informa Healthcare. 2nd ed.
    • Laskin DL, Gardner CR. 2007. Nonparenchymal cells, inflammatory macrophages, and hepatotoxicity. In Drug-Induced Liver Disease, ed. N Kaplowitz, LD DeLeve, pp. 159-84. New York: Informa Healthcare. 2nd ed.
    • (2007) Drug-Induced Liver Disease , pp. 159-84
    • Laskin, D.L.1    Gardner, C.R.2
  • 13
    • 0023037216 scopus 로고
    • Potential role of activated macrophages in acetaminophen hepatotoxicity. I. Isolation and characterization of activated macrophages from rat liver
    • DOI 10.1016/0041-008X(86)90051-7
    • Laskin DL, Pilaro AM. 1986. Potential role of activated macrophages in acetaminophen hepatotoxicity. I. Isolation and characterization of activated macrophages from rat liver. Toxicol. Appl. Pharmacol. 86:204-15 (Pubitemid 17190053)
    • (1986) Toxicology and Applied Pharmacology , vol.86 , Issue.2 , pp. 204-215
    • Laskin, D.L.1    Pilaro, A.M.2
  • 14
    • 0032725438 scopus 로고    scopus 로고
    • Expression of TNF-α and immunohis-tochemical distribution of hepatic macrophage surface markers in carbon tetrachloride-induced chronic liver injury in rats
    • Orfila C, Lepert JC, Alric L, Carrera G, Beraud M, et al. 1999. Expression of TNF-α and immunohis-tochemical distribution of hepatic macrophage surface markers in carbon tetrachloride-induced chronic liver injury in rats. Histochem. J. 31:677-85
    • (1999) Histochem. J. , vol.31 , pp. 677-85
    • Orfila, C.1    Lepert, J.C.2    Alric, L.3    Carrera, G.4    Beraud, M.5
  • 15
    • 0023735167 scopus 로고
    • Activation of liver macrophages following phenobarbital treatment of rats
    • Laskin DL, Robertson FM, Pilaro AM, Laskin JD. 1988. Activation of liver macrophages following phenobarbital treatment of rats. Hepatology 8:1051-55
    • (1988) Hepatology , vol.8 , pp. 1051-55
    • Laskin, D.L.1    Robertson, F.M.2    Pilaro, A.M.3    Laskin, J.D.4
  • 17
    • 0022474493 scopus 로고
    • Accumulation of activated mononuclear phagocytes in the liver following lipopolysaccharide treatment of rats
    • Pilaro AM, Laskin DL. 1986. Accumulation of activated mononuclear phagocytes in the liver following lipopolysaccharide treatment of rats. J. Leukoc. Biol. 40:29-41 (Pubitemid 16067612)
    • (1986) Journal of Leukocyte Biology , vol.40 , Issue.1 , pp. 29-41
    • Pilaro, A.M.1    Laskin, D.L.2
  • 18
    • 0026719323 scopus 로고
    • Lipopolysaccharide treatment of rats alters antigen expression and oxidative metabolism in hepatic macrophages and endothelial cells
    • McCloskey TW, Todaro JA, Laskin DL. 1992. Lipopolysaccharide treatment of rats alters antigen expression and oxidative metabolism in hepatic macrophages and endothelial cells. Hepatology 16:191-203
    • (1992) Hepatology , vol.16 , pp. 191-203
    • McCloskey, T.W.1    Todaro, J.A.2    Laskin, D.L.3
  • 19
    • 0026069261 scopus 로고
    • Modulation of carbon tetrachloride hepatotoxicity and xenobiotic-metabolizing enzymes by corticosterone pretreatment, adrenalectomy and sham surgery
    • Lloyd SA, Franklin MR. 1991. Modulation of carbon tetrachloride hepatotoxicity and xenobiotic-metabolizing enzymes by corticosterone pretreatment, adrenalectomy and sham surgery. Toxicol. Lett. 55:65-75
    • (1991) Toxicol. Lett. , vol.55 , pp. 65-75
    • Lloyd, S.A.1    Franklin, M.R.2
  • 20
    • 0026636286 scopus 로고
    • Effect of pregnenolone-16 α-carbonitrile and dexamethasone on acetaminophen-induced hepatotoxicity in mice
    • Madhu C, Maziasz T, Klaassen CD. 1992. Effect of pregnenolone-16 α-carbonitrile and dexamethasone on acetaminophen-induced hepatotoxicity in mice. Toxicol. Appl. Pharmacol. 115:191-98
    • (1992) Toxicol. Appl. Pharmacol. , vol.115 , pp. 191-98
    • Madhu, C.1    Maziasz, T.2    Klaassen, C.D.3
  • 21
    • 0028948724 scopus 로고
    • Modulation of macrophage functioning abrogates the acute hepatotoxicity of acetaminophen
    • Laskin DL, Gardner CR, Price VF, Jollow DJ. 1995. Modulation of macrophage functioning abrogates the acute hepatotoxicity of acetaminophen. Hepatology 21:1045-50
    • (1995) Hepatology , vol.21 , pp. 1045-50
    • Laskin, D.L.1    Gardner, C.R.2    Price, V.F.3    Jollow, D.J.4
  • 22
    • 0033000310 scopus 로고    scopus 로고
    • Pretreatment of mice with macrophage inactivators decreases acetaminophen hepatotoxicity and the formation of reactive oxygen and nitrogen species
    • DOI 10.1002/hep.510300104
    • Michael SL, Pumford NR, Mayeux PR, Niesman MR, Hinson JA. 1999. Pretreatment of mice with macrophage inactivators decreases acetaminophen hepatotoxicity and the formation of reactive oxygen and nitrogen species. Hepatology 30:186-95 (Pubitemid 29300585)
    • (1999) Hepatology , vol.30 , Issue.1 , pp. 186-195
    • Michael, S.L.1    Pumford, N.R.2    Mayeux, P.R.3    Niesman, M.R.4    Hinson, J.A.5
  • 24
    • 0037359122 scopus 로고    scopus 로고
    • Kupffer cells are responsible for liver cirrhosis induced by carbon tetrachloride
    • DOI 10.1002/jat.892
    • Muriel P, Escobar Y. 2003. Kupffer cells are responsible for liver cirrhosis induced by carbon tetrachlo-ride. J. Appl. Toxicol. 23:103-8 (Pubitemid 36417111)
    • (2003) Journal of Applied Toxicology , vol.23 , Issue.2 , pp. 103-108
    • Muriel, P.1    Escobar, Y.2
  • 25
    • 34047150314 scopus 로고    scopus 로고
    • Role of nitric oxide and reduced glutathione in the protective effects of aminoguanidine, gadolinium chloride and oleanolic acid against acetaminophen-induced hepatic and renal damage
    • DOI 10.1016/j.tox.2007.02.014, PII S0300483X07000996
    • Abdel-Zaher AO, Abdel-Rahman MM, Hafez MM, Omran FM. 2007. Role of nitric oxide and reduced glutathione in the protective effects of aminoguanidine, gadolinium chloride and oleanolic acid against acetaminophen-induced hepatic and renal damage. Toxicology 234:124-34 (Pubitemid 46517830)
    • (2007) Toxicology , vol.234 , Issue.1-2 , pp. 124-134
    • Abdel-Zaher, A.O.1    Abdel-Rahman, M.M.2    Hafez, M.M.3    Omran, F.M.4
  • 26
    • 0029844037 scopus 로고    scopus 로고
    • Role of macrophages in acetaminophen (paracetamol)-induced hepatotoxicity
    • DOI 10.1002/(SICI)1096-9896(199608)179:4<432::AID-PATH609>3.0.CO;2- S
    • Goldin RD, Ratnayaka ID, Breach CS, Brown IN, Wickramasinghe SN. 1996. Role of macrophages in acetaminophen (paracetamol)-induced hepatotoxicity. J. Pathol. 179:432-35 (Pubitemid 26276115)
    • (1996) Journal of Pathology , vol.179 , Issue.4 , pp. 432-435
    • Goldin, R.D.1    Ratnayaka, I.D.2    Breach, C.S.3    Brown, I.N.4    Wickramasinghe, S.N.5
  • 28
    • 0028340111 scopus 로고
    • Blockade of liver macrophages by gadolinium chloride reduces lethality in endotoxemic rats - Analysis of mechanisms of lethality in endotoxemia
    • Iimuro Y, Yamamoto M, Kohno H, Itakura J, Fujii H, Matsumoto Y. 1994. Blockade of liver macrophages by gadolinium chloride reduces lethality in endotoxemic rats-analysis of mechanisms of lethality in endotoxemia. J. Leukoc. Biol. 55:723-28 (Pubitemid 24207401)
    • (1994) Journal of Leukocyte Biology , vol.55 , Issue.6 , pp. 723-728
    • Iimuro, Y.1    Yamamoto, M.2    Kohno, H.3    Itakura, J.4    Fujii, H.5    Matsumoto, Y.6
  • 29
    • 0028858833 scopus 로고
    • Role of Kupffer cells in rat liver injury induced by diethyldithio- carbamate
    • Ishiyama H, Ogino K, Hobara T. 1995. Role of Kupffer cells in rat liver injury induced by diethyldithio-carbamate. Eur. J. Pharmacol. 292:135-41
    • (1995) Eur. J. Pharmacol. , vol.292 , pp. 135-41
    • Ishiyama, H.1    Ogino, K.2    Hobara, T.3
  • 30
    • 0030914902 scopus 로고    scopus 로고
    • Gadolinium chloride blocks alcohol-dependent liver toxicity in rats treated chronically with intragastric alcohol despite the induction of CYP2E1
    • Koop DR, Klopfenstein B, Iimuro Y, Thurman RG. 1997. Gadolinium chloride blocks alcohol-dependent liver toxicity in rats treated chronically with intragastric alcohol despite the induction of CYP2E1. Mol. Pharmacol. 51:944-50 (Pubitemid 27249127)
    • (1997) Molecular Pharmacology , vol.51 , Issue.6 , pp. 944-950
    • Koop, D.R.1    Klopfenstein, B.2    Iimuro, Y.3    Thurman, R.G.4
  • 31
    • 0036566502 scopus 로고    scopus 로고
    • Gadolinium chloride pretreatment prevents cadmium chloride-induced liver damage in both wild-type and MT-null mice
    • DOI 10.1006/taap.2002.9385
    • Harstad EB, Klaassen CD. 2002. Gadolinium chloride pretreatment prevents cadmium chloride-induced liver damage in both wild-type and MT-null mice. Toxicol. Appl. Pharmacol. 180:178-85 (Pubitemid 34526458)
    • (2002) Toxicology and Applied Pharmacology , vol.180 , Issue.3 , pp. 178-185
    • Harstad, E.B.1    Klaassen, C.D.2
  • 32
    • 0042261675 scopus 로고    scopus 로고
    • Depletion of Kupffer cell function by gadolinium chloride attenuates thioacetamide-induced hepatotoxicity: Expression of metallothionein and HSP70
    • DOI 10.1016/S0006-2952(03)00443-X
    • Andres D, Sanchez-Reus I, Bautista M, Cascales M. 2003. Depletion of Kupffer cell function by gadolinium chloride attenuates thioacetamide-induced hepatotoxicity: expression of metallothionein and HSP70. Biochem. Pharmacol. 66:917-26 (Pubitemid 37083588)
    • (2003) Biochemical Pharmacology , vol.66 , Issue.6 , pp. 917-926
    • Andres, D.1    Sanchez-Reus, I.2    Bautista, M.3    Cascales, M.4
  • 33
    • 0019829009 scopus 로고
    • Modification of galactosamine-induced liver injury in rats by reticuloendothelial system stimulation or depression
    • DOI 10.1002/hep.1840010204
    • Al-Tuwaijri A, Akdamar K, Di Luzio NR. 1981. Modification of galactosamine-induced liver injury in rats by reticuloendothelial system stimulation or depression. Hepatology 1:107-13 (Pubitemid 11055067)
    • (1981) Hepatology , vol.1 , Issue.2 , pp. 107-113
    • Al-Tuwaijri, A.1    Akdamar, K.2    Di Luzio, N.R.3
  • 34
    • 0025686095 scopus 로고
    • Biphasic modulation of acetaminophen bioactivation and hepatotoxicity by pretreatment with the interferon inducer polyinosinic-polycytidylic acid
    • Kalabis GM, Wells PG. 1990. Biphasic modulation of acetaminophen bioactivation and hepatotoxicity by pretreatment with the interferon inducer polyinosinic-polycytidylic acid. J. Pharmacol. Exp. Ther. 255:1408-19
    • (1990) J. Pharmacol. Exp. Ther. , vol.255 , pp. 1408-19
    • Kalabis, G.M.1    Wells, P.G.2
  • 36
    • 62549122055 scopus 로고    scopus 로고
    • Th1/Th2 cytokine balance as a determinant of acetaminophen-induced liver injury
    • Masubuchi Y, Sugiyama S, Horie T. 2009. Th1/Th2 cytokine balance as a determinant of acetaminophen-induced liver injury. Chem. Biol. Interact. 179:273-79
    • (2009) Chem. Biol. Interact. , vol.179 , pp. 273-79
    • Masubuchi, Y.1    Sugiyama, S.2    Horie, T.3
  • 38
    • 32544432347 scopus 로고    scopus 로고
    • Distinct roles of NF-κB p50 in the regulation of acetaminophen- induced inflammatory mediator production and hepatotoxicity
    • DOI 10.1016/j.taap.2005.06.024, PII S0041008X05003984
    • Dambach DM, Durham SK, Laskin JD, Laskin DL. 2006. Distinct roles of NF-κB p50 in the regulation of acetaminophen-induced inflammatory mediator production and hepatotoxicity. Toxicol. Appl. Pharmacol. 211:157-65 (Pubitemid 43238309)
    • (2006) Toxicology and Applied Pharmacology , vol.211 , Issue.2 , pp. 157-165
    • Dambach, D.M.1    Durham, S.K.2    Laskin, J.D.3    Laskin, D.L.4
  • 39
    • 77956266529 scopus 로고    scopus 로고
    • Early growth response-1 attenuates liver injury and promotes hepatoprotection after carbon tetrachloride exposure in mice
    • Pritchard MT, Cohen JI, Roychowdhury S, Pratt BT, Nagy LE. 2010. Early growth response-1 attenuates liver injury and promotes hepatoprotection after carbon tetrachloride exposure in mice. J. Hepatol. 53:655-62
    • (2010) J. Hepatol. , Issue.53 , pp. 655-62
    • Pritchard, M.T.1    Cohen, J.I.2    Roychowdhury, S.3    Pratt, B.T.4    Nagy, L.E.5
  • 40
    • 0035312581 scopus 로고    scopus 로고
    • Distinct roles of tumor necrosis factor-α and nitric oxide in acute liver injury induced by carbon tetrachloride in mice
    • DOI 10.1006/taap.2000.9133
    • Morio LA, Chiu H, Sprowles KA, Zhou P, Heck DE, et al. 2001. Distinct roles of tumor necrosis factor-α and nitric oxide in acute liver injury induced by carbon tetrachloride in mice. Toxicol. Appl. Pharmacol. 172:44-51 (Pubitemid 32281410)
    • (2001) Toxicology and Applied Pharmacology , vol.172 , Issue.1 , pp. 44-51
    • Morio, L.A.1    Chiu, H.2    Sprowles, K.A.3    Zhou, P.4    Heck, D.E.5    Gordon, M.K.6    Laskin, D.L.7
  • 41
    • 0030330332 scopus 로고    scopus 로고
    • Modulation of Kupffer cell activity by gadolinium chloride in endotoxemic rats
    • Vollmar B, Ruttinger D, Wanner GA, Leiderer R, Menger MD. 1996. Modulation of Kupffer cell activity by gadolinium chloride in endotoxemic rats. Shock 6:434-41 (Pubitemid 126727786)
    • (1996) Shock , vol.6 , Issue.6 , pp. 434-441
    • Vollmar, B.1    Ruttinger, D.2    Wanner, G.A.3    Leiderer, R.4    Menger, M.D.5
  • 42
  • 46
    • 34250733492 scopus 로고    scopus 로고
    • Hepatoprotective role of endogenous interleukin-13 in a murine model of acetaminophen-induced liver disease
    • DOI 10.1021/tx600349f
    • Yee SB, Bourdi M, Masson MJ, Pohl LR. 2007. Hepatoprotective role of endogenous interleukin-13 in a murine model of acetaminophen-induced liver disease. Chem. Res. Toxicol. 20:734-44 (Pubitemid 46953680)
    • (2007) Chemical Research in Toxicology , vol.20 , Issue.5 , pp. 734-744
    • Yee, S.B.1    Bourdi, M.2    Masson, M.J.3    Pohl, L.R.4
  • 47
    • 77956419029 scopus 로고    scopus 로고
    • Role of STK in mouse liver macrophage and en-dothelial cell responsiveness during acute endotoxemia
    • Laskin DL, Chen L, Hankey PA, Laskin JD. 2010. Role of STK in mouse liver macrophage and en-dothelial cell responsiveness during acute endotoxemia. J. Leukoc. Biol. 88:373-82
    • (2010) J. Leukoc. Biol. , Issue.88 , pp. 373-82
    • Laskin, D.L.1    Chen, L.2    Hankey, P.A.3    Laskin, J.D.4
  • 48
    • 79951990141 scopus 로고    scopus 로고
    • Classical and alternative activation of rat liver Kupffer and endothelial cells: Impact of acetaminophen (APAP)
    • (Abstr.)
    • Liu Y, Gardner CR, Laskin JD, Laskin DL. 2010. Classical and alternative activation of rat liver Kupffer and endothelial cells: impact of acetaminophen (APAP). The Toxicologist 114:158 (Abstr.)
    • (2010) The Toxicologist , vol.114 , pp. 158
    • Liu, Y.1    Gardner, C.R.2    Laskin, J.D.3    Laskin, D.L.4
  • 50
    • 0036154452 scopus 로고    scopus 로고
    • Protection against acetaminophen-induced liver injury and lethality by interleukin 10: Role of inducible nitric oxide synthase
    • DOI 10.1053/jhep.2002.30956
    • Bourdi M, Masubuchi Y, Reilly TP, Amouzadeh HR, Martin JL, et al. 2002. Protection against acetaminophen-induced liver injury and lethality byinterleukin 10: role of inducible nitric oxide synthase. Hepatology 35:289-98 (Pubitemid 34106367)
    • (2002) Hepatology , vol.35 , Issue.2 , pp. 289-298
    • Bourdi, M.1    Masubuchi, Y.2    Reilly, T.P.3    Amouzadeh, H.R.4    Martin, J.L.5    George, J.W.6    Shah, A.G.7    Pohl, L.R.8
  • 59
    • 0036009458 scopus 로고    scopus 로고
    • Deficiency in inducible nitric oxide synthase protects mice from ozone-induced lung inflammation and tissue injury
    • Fakhrzadeh L, Laskin JD, Laskin DL. 2002. Deficiency in inducible nitric oxide synthase protects mice from ozone-induced lung inflammation and tissue injury. Am. J. Respir. Cell Mol. Biol. 26:413-19 (Pubitemid 34253925)
    • (2002) American Journal of Respiratory Cell and Molecular Biology , vol.26 , Issue.4 , pp. 413-419
    • Fakhrzadeh, L.1    Laskin, J.D.2    Laskin, D.L.3
  • 60
    • 0029353851 scopus 로고
    • Inhibition of macrophages with gadolinium chloride abrogates ozone-induced pulmonary injury and inflammatory mediator production
    • Pendino KJ, Meidhof TM, Heck DE, Laskin JD, Laskin DL. 1995. Inhibition of macrophages with gadolinium chloride abrogates ozone-induced pulmonary injury and inflammatory mediator production. Am. J. Respir. Cell Mol. Biol. 13:125-32
    • (1995) Am. J. Respir. Cell Mol. Biol. , vol.13 , pp. 125-32
    • Pendino, K.J.1    Meidhof, T.M.2    Heck, D.E.3    Laskin, J.D.4    Laskin, D.L.5
  • 61
    • 0027131380 scopus 로고
    • Enhanced production of nitric oxide by rat alveolar macrophages after inhalation of a pulmonary irritant is associated with increased expression of nitric oxide synthase
    • Pendino KJ, Laskin JD, Shuler RL, Punjabi CJ, Laskin DL. 1993. Enhanced production of nitric oxide by rat alveolar macrophages after inhalation of a pulmonary irritant is associated with increased expression of nitric oxide synthase. J. Immunol. 151:7196-205 (Pubitemid 24001094)
    • (1993) Journal of Immunology , vol.151 , Issue.12 , pp. 7196-7205
    • Pendino, K.J.1    Laskin, J.D.2    Shuler, R.L.3    Punjabi, C.J.4    Laskin, D.L.5
  • 63
    • 1542284719 scopus 로고    scopus 로고
    • Superoxide Dismutase-Overexpressing Mice Are Resistant to Ozone-Induced Tissue Injury and Increases in Nitric Oxide and Tumor Necrosis Factor-α
    • DOI 10.1165/rcmb.2003-0044OC
    • Fakhrzadeh L, Laskin JD, Gardner CR, Laskin DL. 2004. Superoxide dismutase-overexpressing mice are resistant to ozone-induced tissue injury and increases in nitric oxide and tumor necrosis factor-α. Am. J. Respir. Cell Mol. Biol. 30:280-87 (Pubitemid 38315380)
    • (2004) American Journal of Respiratory Cell and Molecular Biology , vol.30 , Issue.3 , pp. 280-287
    • Fakhrzadeh, L.1    Laskin, J.D.2    Gardner, C.R.3    Laskin, D.L.4
  • 66
    • 33646888693 scopus 로고    scopus 로고
    • In situ assessment of oxidant and nitrogenic stress in bleomycin pulmonary fibrosis
    • DOI 10.1007/s00418-005-0116-7
    • Inghilleri S, Morbini P, Oggionni T, Barni S, Fenoglio C. 2006. In situ assessment of oxidant and nitrogenic stress in bleomycin pulmonary fibrosis. Histochem. Cell Biol. 125:661-69 (Pubitemid 43785960)
    • (2006) Histochemistry and Cell Biology , vol.125 , Issue.6 , pp. 661-669
    • Inghilleri, S.1    Morbini, P.2    Oggionni, T.3    Barni, S.4    Fenoglio, C.5
  • 68
    • 0028503301 scopus 로고
    • Enhanced production of interleukin-1, tumor necrosis factor-α, and fibronectin by rat lung phagocytes following inhalation of a pulmonary irritant
    • Pendino KJ, Shuler RL, Laskin JD, Laskin DL. 1994. Enhanced production of interleukin-1, tumor necrosis factor-α, and fibronectin by rat lung phagocytes following inhalation of a pulmonary irritant. Am. J. Respir. Cell Mol. Biol. 11:279-86
    • (1994) Am. J. Respir. Cell Mol. Biol. , vol.11 , pp. 279-86
    • Pendino, K.J.1    Shuler, R.L.2    Laskin, J.D.3    Laskin, D.L.4
  • 70
    • 70350681851 scopus 로고    scopus 로고
    • Treatment with dexamethasone or liposome-encapsuled vitamin e provides beneficial effects after chemical-induced lung injury
    • Wigenstam E, Rocksen D, Ekstrand-Hammarstrom B, Bucht A. 2009. Treatment with dexamethasone or liposome-encapsuled vitamin E provides beneficial effects after chemical-induced lung injury. Inhal. Toxicol. 21:958-64
    • (2009) Inhal. Toxicol. , vol.21 , pp. 958-64
    • Wigenstam, E.1    Rocksen, D.2    Ekstrand-Hammarstrom, B.3    Bucht, A.4
  • 71
    • 58149211879 scopus 로고
    • Expression of inducible nitric oxide synthase mRNA in Brown Norway rats exposed to ozone: Effect of dexamethasone
    • Haddad EB, Liu SF, Salmon M, Robichaud A, Barnes PJ, Chung KF. 1995. Expression of inducible nitric oxide synthase mRNA in Brown Norway rats exposed to ozone: effect of dexamethasone. Eur. J. Pharmacol. 293:287-90
    • (1995) Eur. J. Pharmacol. , vol.293 , pp. 287-90
    • Haddad, E.B.1    Liu, S.F.2    Salmon, M.3    Robichaud, A.4    Barnes, P.J.5    Chung, K.F.6
  • 72
    • 0031062289 scopus 로고    scopus 로고
    • Modulation of silica-induced pulmonary toxicity by dexamethasone- containing liposomes
    • DOI 10.1006/taap.1996.8057
    • DiMatteo M, Reasor MJ. 1997. Modulation of silica-induced pulmonary toxicity by dexamethasone-containing liposomes. Toxicol. Appl. Pharmacol. 142:411-21 (Pubitemid 28381032)
    • (1997) Toxicology and Applied Pharmacology , vol.142 , Issue.2 , pp. 411-421
    • Dimatteo, M.1    Reasor, M.J.2
  • 73
    • 33646024900 scopus 로고    scopus 로고
    • Short courses of low dose dexamethasone delay bleomycin-induced lung fibrosis in rats
    • Chen F, Gong L, Zhang L, Wang H, Qi X, et al. 2006. Short courses of low dose dexamethasone delay bleomycin-induced lung fibrosis in rats. Eur. J. Pharmacol. 536:287-95
    • (2006) Eur. J. Pharmacol. , vol.536 , pp. 287-95
    • Chen, F.1    Gong, L.2    Zhang, L.3    Wang, H.4    Qi, X.5
  • 74
    • 0016624750 scopus 로고
    • Effects of pretreatment with anti-inflammatory drugs on ozone-induced lung damage in rats
    • Giri SN, Benson J, Siegel DM, Rice SA, Schiedt M. 1975. Effects of pretreatment with anti-inflammatory drugs on ozone-induced lung damage in rats. Proc. Soc. Exp. Biol. Med. 150:810-14
    • (1975) Proc. Soc. Exp. Biol. Med. , vol.150 , pp. 810-14
    • Giri, S.N.1    Benson, J.2    Siegel, D.M.3    Rice, S.A.4    Schiedt, M.5
  • 75
    • 0026890745 scopus 로고
    • Attenuation of ozone-induced airway permeability in rats by pretreatment with cyclophosphamide, FPL 55712, and indomethacin
    • Bhalla DK, Daniels DS, Luu NT. 1992. Attenuation of ozone-induced airway permeability in rats by pretreatment with cyclophosphamide, FPL 55712, and indomethacin. Am. J. Respir. Cell Mol. Biol. 7:73-80
    • (1992) Am. J. Respir. Cell Mol. Biol. , vol.7 , pp. 73-80
    • Bhalla, D.K.1    Daniels, D.S.2    Luu, N.T.3
  • 76
    • 1442286472 scopus 로고    scopus 로고
    • Efficient depletion of alveolar macrophages using intratracheally inhaled aerosols of liposome-encapsulated clodronate
    • Elder AC, Gelein R, Oberdorster G, Finkelstein J, Notter R, Wang Z. 2004. Efficient depletion of alveolar macrophages using intratracheally inhaled aerosols of liposome-encapsulated clodronate. Exp. Lung Res. 30:105-20 (Pubitemid 38293712)
    • (2004) Experimental Lung Research , vol.30 , Issue.2 , pp. 105-120
    • Elden, A.C.P.1    Gelein, R.2    Oberdorster, G.3    Finkelstein, J.4    Notter, R.5    Wang, Z.6
  • 80
    • 0027736378 scopus 로고
    • Stimulation of alveolar macrophagesbyBCG vaccine enhances the processoflungfibrosis inducedbybleomycin.Folia Histochem
    • Chyczewska E, Chyczewski L, Bankowski E, Sulkowski S, Niklinski J. 1993. Stimulation of alveolar macrophagesbyBCG vaccine enhances the processoflungfibrosis inducedbybleomycin.Folia Histochem. Cytobiol. 31:113-16
    • (1993) Cytobiol. , vol.31 , pp. 113-16
    • Chyczewska, E.1    Chyczewski, L.2    Bankowski, E.3    Sulkowski, S.4    Niklinski, J.5
  • 82
    • 0037265240 scopus 로고    scopus 로고
    • Alternative activation of macrophages
    • DOI 10.1038/nri978
    • Gordon S. 2003. Alternative activation of macrophages. Nat. Rev. Immunol. 3:23-35 (Pubitemid 37328697)
    • (2003) Nature Reviews Immunology , vol.3 , Issue.1 , pp. 23-35
    • Gordon, S.1
  • 83
    • 33845945947 scopus 로고    scopus 로고
    • MARCO mediates silica uptake and toxicity in alveolar macrophages from C57BL/6 mice
    • DOI 10.1074/jbc.M605229200
    • Hamilton RF Jr, Thakur SA, Mayfair JK, Holian A. 2006. MARCO mediates silica uptake and toxicity in alveolar macrophages from C57BL/6 mice. J. Biol. Chem. 281:34218-26 (Pubitemid 46036630)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.45 , pp. 34218-34226
    • Hamilton Jr., R.F.1    Thakur, S.A.2    Mayfair, J.K.3    Holian, A.4
  • 85
    • 57649233540 scopus 로고    scopus 로고
    • Modulation of cytokine production and silica-induced lung fibrosis by inhibitors of aminopeptidase N and of dipeptidyl peptidase-IV-related proteases
    • Kuhlmann UC, Chwieralski CE, Van Den Brule S, Rocken C, Reinhold D, et al. 2009. Modulation of cytokine production and silica-induced lung fibrosis by inhibitors of aminopeptidase N and of dipeptidyl peptidase-IV-related proteases. Life Sci. 84:1-11
    • (2009) Life Sci. , vol.84 , pp. 1-11
    • Kuhlmann, U.C.1    Chwieralski, C.E.2    Van Den Brule, S.3    Rocken, C.4    Reinhold, D.5
  • 86
    • 77950379862 scopus 로고    scopus 로고
    • Serum amyloid P therapeuti-cally attenuates murine bleomycin-induced pulmonary fibrosis via its effects on macrophages
    • Murray LA, Rosada R, Moreira AP, Joshi A, Kramer MS, et al. 2010. Serum amyloid P therapeuti-cally attenuates murine bleomycin-induced pulmonary fibrosis via its effects on macrophages. PLoS One 5:e9683
    • (2010) PLoS One , vol.5
    • Murray, L.A.1    Rosada, R.2    Moreira, A.P.3    Joshi, A.4    Kramer, M.S.5
  • 89
    • 43349091452 scopus 로고    scopus 로고
    • The IL-4Rα pathway in macrophages and its potential role in silica-induced pulmonary fibrosis
    • DOI 10.1189/jlb.0807533
    • Migliaccio CT, Buford MC, Jessop F, Holian A. 2008. The IL-4Rα pathway in macrophages and its potential role in silica-induced pulmonary fibrosis. J. Leukoc. Biol. 83:630-39 (Pubitemid 351966873)
    • (2008) Journal of Leukocyte Biology , vol.83 , Issue.3 , pp. 630-639
    • Migliaccio, C.T.1    Buford, M.C.2    Jessop, F.3    Holian, A.4
  • 93
    • 9744262517 scopus 로고    scopus 로고
    • C-C chemokine receptor 2 (CCR2) deficiency improves bleomycin-induced pulmonary fibrosis by attenuation of both macrophage infiltration and production of macrophage-derived matrix metalloproteinases
    • DOI 10.1002/path.1667
    • Okuma T, Terasaki Y, Kaikita K, Kobayashi H, Kuziel WA, et al. 2004. C-C chemokine receptor 2 (CCR2) deficiency improves bleomycin-induced pulmonary fibrosis by attenuation of both macrophage infiltration and production of macrophage-derived matrix metalloproteinases. J. Pathol. 204:594-604 (Pubitemid 39585959)
    • (2004) Journal of Pathology , vol.204 , Issue.5 , pp. 594-604
    • Okuma, T.1    Terasaki, Y.2    Kaikita, K.3    Kobayashi, H.4    Kuziel, W.A.5    Kawasuji, M.6    Takeya, M.7
  • 95
    • 0034492958 scopus 로고    scopus 로고
    • NOS-2 mediates the protective anti-inflammatory and antifibrotic effects of the Th1-inducing adjuvant, IL-12, in a Th2 model of granulomatous disease
    • HesseM,Cheever AW, Jankovic D,Wynn TA. 2000. NOS-2 mediates the protective anti-inflammatory and antifibrotic effects of the Th1-inducing adjuvant, IL-12, in a Th2 model of granulomatous disease. Am. J. Pathol. 157:945-55 (Pubitemid 32109386)
    • (2000) American Journal of Pathology , vol.157 , Issue.3 , pp. 945-955
    • Hesse, M.1    Cheever, A.W.2    Jankovic, D.3    Wynn, T.A.4
  • 96
    • 0022407632 scopus 로고
    • Oxygen-derived free radicals promote hepatic injury in the rat
    • Arthur MJP, Bentley IS, Tanner AR, Saunders PK, Millward-Sadler GH, Wright R. 1985. Oxygen-derived free radicals promote hepatic injury in the rat. Gastroenterology 89:1114-22 (Pubitemid 16231579)
    • (1985) Gastroenterology , vol.89 , Issue.5 , pp. 1114-1122
    • Arthur, M.J.P.1    Bentley, I.S.2    Tanner, A.R.3
  • 98
    • 0027420167 scopus 로고
    • Characterization of vitamin A potentiation of carbon tetrachloride- induced liver injury
    • DOI 10.1006/taap.1993.1070
    • Elsisi AE, Hall P, Sim WL, Earnest DL, Sipes IG. 1993. Characterization of vitamin A potentiation of carbon tetrachloride-induced liver injury. Toxicol. Appl. Pharmacol. 119:280-88 (Pubitemid 23122839)
    • (1993) Toxicology and Applied Pharmacology , vol.119 , Issue.2 , pp. 280-288
    • Elsisi, A.E.D.1    Hall, P.2    Sim, W.-L.W.3    Earnest, D.L.4    Sipes, I.G.5
  • 100
    • 0027536821 scopus 로고
    • Modulation of 1,2-dichlorobenzene hepatotoxicity in the Fischer-344 rat by a scavenger of superoxide anions and an inhibitor of Kupffer cells
    • DOI 10.1006/taap.1993.1061
    • Guanawardhana L, Mobley SA, Sipes IG. 1993. Modulation of 1,2-dichlorobenzene hepatotoxicity in the Fischer-344 rat by a scavenger of superoxide anions and an inhibitor of Kupffer cells. Toxicol. Appl. Pharmacol. 119:205-13 (Pubitemid 23122830)
    • (1993) Toxicology and Applied Pharmacology , vol.119 , Issue.2 , pp. 205-213
    • Gunawardhana, L.1    Mobley, S.A.2    Sipes, I.G.3
  • 101
    • 0026569120 scopus 로고
    • Endotoxin treatment protects rats against ozone-induced lung edema: With evidence for the role of manganese superoxide dismutase
    • Rahman I, Massaro D. 1992. Endotoxin treatment protects rats against ozone-induced lung edema: with evidence for the role of manganese superoxide dismutase. Toxicol. Appl. Pharmacol. 113:13-18
    • (1992) Toxicol. Appl. Pharmacol. , vol.113 , pp. 13-18
    • Rahman, I.1    Massaro, D.2
  • 102
    • 0026059067 scopus 로고
    • Interleukin 1 protects rats against oxygen toxicity
    • Tsan MF, Lee CY, White JE. 1991. Interleukin 1 protects rats against oxygen toxicity. J. Appl. Physiol. 71:688-97
    • (1991) J. Appl. Physiol. , vol.71 , pp. 688-97
    • Tsan, M.F.1    Lee, C.Y.2    White, J.E.3
  • 103
    • 0028944511 scopus 로고
    • Attenuation of hyperoxic lung injury in rabbits with superoxide dismutase: Effects on inflammatory mediators
    • Mikawa K, Nishina K, Maekawa N, Obara H. 1995. Attenuation of hyperoxic lung injury in rabbits with superoxide dismutase: effects on inflammatory mediators. Acta Anaesthesiol. Scand. 39:317-22
    • (1995) Acta Anaesthesiol. Scand. , vol.39 , pp. 317-22
    • Mikawa, K.1    Nishina, K.2    Maekawa, N.3    Obara, H.4
  • 107
    • 26844552427 scopus 로고    scopus 로고
    • Overexpression of extracellular superoxide dismutase reduces acute radiation-induced lung toxicity
    • Rabbani ZN, Anscher MS, Folz RJ, Archer E, Huang H, et al. 2005. Overexpression of extracellular superoxide dismutase reduces acute radiation-induced lung toxicity. BMC Cancer 5:59-71
    • (2005) BMC Cancer , vol.5 , pp. 59-71
    • Rabbani, Z.N.1    Anscher, M.S.2    Folz, R.J.3    Archer, E.4    Huang, H.5
  • 108
    • 77956243493 scopus 로고    scopus 로고
    • Nitric oxide pathways in toxic responses
    • ed. B Ballantyne, T Marrs, T Syversen Hoboken, NJ: Wiley
    • Laskin JD, Heck DE, Laskin DL. 2009. Nitric oxide pathways in toxic responses. In General and Applied Toxicology, ed. B Ballantyne, T Marrs, T Syversen, pp. 425-38. Hoboken, NJ: Wiley
    • (2009) General and Applied Toxicology , pp. 425-38
    • Laskin, J.D.1    Heck, D.E.2    Laskin, D.L.3
  • 109
    • 33845398215 scopus 로고    scopus 로고
    • Biochemical and functional characterization of three activated macrophage populations
    • DOI 10.1189/jlb.0406249
    • Edwards JP, Zhang X, Frauwirth KA, Mosser DM. 2006. Biochemical and functional characterization of three activated macrophage populations. J. Leukoc. Biol. 80:1298-307 (Pubitemid 44904968)
    • (2006) Journal of Leukocyte Biology , vol.80 , Issue.6 , pp. 1298-1307
    • Edwards, J.P.1    Zhang, X.2    Frauwirth, K.A.3    Mosser, D.M.4
  • 110
    • 51449116419 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase expressions in different lung injury models and the protective effect of aminoguanidine
    • Yeh DY, Feng NH, Chen CF, Lin HI, Wang D. 2008. Inducible nitric oxide synthase expressions in different lung injury models and the protective effect of aminoguanidine. Transplant. Proc. 40:2178-81
    • (2008) Transplant. Proc. , vol.40 , pp. 2178-81
    • Yeh, D.Y.1    Feng, N.H.2    Chen, C.F.3    Lin, H.I.4    Wang, D.5
  • 111
    • 26244464290 scopus 로고    scopus 로고
    • Inhibition or knock out of inducible nitric oxide synthase result in resistance to bleomycin-induced lung injury
    • Genovese T, Cuzzocrea S, Di Paola R, Failla M, Mazzon E, et al. 2005. Inhibition or knock out of inducible nitric oxide synthase result in resistance to bleomycin-induced lung injury. Respir. Res. 6:58
    • (2005) Respir. Res. , vol.6 , pp. 58
    • Genovese, T.1    Cuzzocrea, S.2    Di Paola, R.3    Failla, M.4    Mazzon, E.5
  • 113
    • 34249110390 scopus 로고    scopus 로고
    • Involvement of NADPH oxidase and iNOS in rodent pulmonary cytokine responses to urban air and mineral particles
    • DOI 10.1080/08958370701353528, PII 778849815
    • Becher R, Bucht A, Ovrevik J, Hongslo JK, Dahlman HJ, et al. 2007. Involvement of NADPH oxidase and iNOS in rodent pulmonary cytokine responses to urban air and mineral particles. Inhal. Toxicol. 19:645-55 (Pubitemid 46788946)
    • (2007) Inhalation Toxicology , vol.19 , Issue.8 , pp. 645-655
    • Becher, R.1    Bucht, A.2    Ovrevik, J.3    Hongslo, J.K.4    Dahlman, H.J.5    Samuelsen, J.T.6    Schwarze, P.E.7
  • 115
    • 3042687470 scopus 로고    scopus 로고
    • Role of inducible nitric oxide synthase-derived nitric oxide in silica-induced pulmonary inflammation and fibrosis
    • DOI 10.1080/15287390490447296
    • Zeidler P, Hubbs A, Battelli L, Castranova V. 2004. Role of inducible nitric oxide synthase-derived nitric oxide in silica-induced pulmonary inflammation and fibrosis. J. Toxicol. Environ. Health A 67:1001-26 (Pubitemid 38822691)
    • (2004) Journal of Toxicology and Environmental Health - Part A , vol.67 , Issue.13 , pp. 1001-1026
    • Zeidler, P.C.1    Hubbs, A.2    Battelli, L.3    Castranova, V.4
  • 116
    • 47849105932 scopus 로고    scopus 로고
    • Roles for proteinases in the pathogenesis of chronic obstructive pulmonary disease
    • Owen CA. 2008. Roles for proteinases in the pathogenesis of chronic obstructive pulmonary disease. Int. J. Chronic Obstr. Pulm. Dis. 3:253-68 (Pubitemid 352037885)
    • (2008) International Journal of COPD , vol.3 , Issue.2 , pp. 253-268
    • Owen, C.A.1
  • 117
    • 0041732104 scopus 로고    scopus 로고
    • Differential production of metalloproteinases after instilling various urban air particle samples to rat lung
    • DOI 10.1080/01902140303753
    • Adamson IY, Vincent R, Bakowska J. 2003. Differential production of metalloproteinases after instilling various urban air particle samples to rat lung. Exp. Lung Res. 29:375-88 (Pubitemid 36999989)
    • (2003) Experimental Lung Research , vol.29 , Issue.6 , pp. 375-388
    • Adamson, I.Y.R.1    Vincent, R.2    Bakowska, J.3
  • 118
    • 0019421038 scopus 로고
    • Proteolytic enzymes released by liver macrophages may promote hepatic injury in a rat model of hepatic damage
    • Tanner A, Keyhani A, Reiner R, Holdstock G, Wright R. 1981. Proteolytic enzymes released by liver macrophages may promote injury in a rat model of hepatic damage. Gastroenterology 80:647-54 (Pubitemid 11137741)
    • (1981) Gastroenterology , vol.80 , Issue.4 , pp. 647-654
    • Tanner, A.1    Keyhani, A.2    Reiner, R.3
  • 119
    • 47949111247 scopus 로고    scopus 로고
    • Contribution of hepatic stellate cells and matrix metalloproteinase 9 in acute liver failure
    • DOI 10.1111/j.1478-3231.2008.01775.x
    • Yan C, Zhou L, Han YP. 2008. Contribution of hepatic stellate cells and matrix metalloproteinase 9 in acute liver failure. Liver Int. 28:959-71 (Pubitemid 352044444)
    • (2008) Liver International , vol.28 , Issue.7 , pp. 959-971
    • Yan, C.1    Zhou, L.2    Han, Y.-P.3
  • 120
    • 77953986092 scopus 로고    scopus 로고
    • Differential expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in thioacetamide-induced chronic liver injury
    • Park SY, Shin HW, Lee KB, Lee MJ, Jang JJ. 2010. Differential expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in thioacetamide-induced chronic liver injury. J. Korean Med. Sci. 25:570-76
    • (2010) J. Korean Med. Sci. , vol.25 , pp. 570-76
    • Park, S.Y.1    Shin, H.W.2    Lee, K.B.3    Lee, M.J.4    Jang, J.J.5
  • 121
    • 67849109680 scopus 로고    scopus 로고
    • Evaluation of protease inhibitors and an antioxidant for treatment of sulfur mustard-induced toxic lung injury
    • Anderson DR, Taylor SL, Fetterer DP, Holmes WW. 2009. Evaluation of protease inhibitors and an antioxidant for treatment of sulfur mustard-induced toxic lung injury. Toxicology 263:41-46
    • (2009) Toxicology , vol.263 , pp. 41-46
    • Anderson, D.R.1    Taylor, S.L.2    Fetterer, D.P.3    Holmes, W.W.4
  • 123
    • 43049165310 scopus 로고    scopus 로고
    • Role of innate immune cells and their products in lung immunopathology
    • Suzuki T, Chow CW, Downey GP. 2008. Role of innate immune cells and their products in lung immunopathology. Int. J. Biochem. Cell Biol. 40:1348-61
    • (2008) Int. J. Biochem. Cell Biol. , vol.40 , pp. 1348-61
    • Suzuki, T.1    Chow, C.W.2    Downey, G.P.3
  • 124
    • 0027491126 scopus 로고
    • Characterization of alveolar macrophage eicosanoid production in a non-human primate model of mineral dust exposure
    • DOI 10.1016/0090-6980(93)90004-Q
    • Kuhn DC, Griffith JW, Stauffer JL, Riling S, Demers LM. 1993. Characterization of alveolar macrophage eicosanoid production in a non-human primate model of mineral dust exposure. Prostaglandins 46:207-20 (Pubitemid 23286112)
    • (1993) Prostaglandins , vol.46 , Issue.3 , pp. 207-220
    • Kuhn, D.C.1    Griffith, J.W.2    Stauffer, J.L.3    Riling, S.4    Demers, L.M.5
  • 126
    • 0035680610 scopus 로고    scopus 로고
    • Activation of Kupffer cells during the course of carbon tetrachloride-induced liver injury and fibrosis in rats
    • DOI 10.1006/exmp.2001.2399
    • Luckey SW, Petersen DR. 2001. Activation of Kupffer cells during the course of carbon tetrachloride- induced liver injury and fibrosis in rats. Exp. Mol. Pathol. 71:226-40 (Pubitemid 34060097)
    • (2001) Experimental and Molecular Pathology , vol.71 , Issue.3 , pp. 226-240
    • Luckey, S.W.1    Petersen, D.R.2
  • 129
    • 0037436409 scopus 로고    scopus 로고
    • Late administration of COX-2 inhibitors minimize hepatic necrosis in chloroform induced liver injury
    • DOI 10.1016/S0300-483X(02)00594-2, PII S0300483X02005942
    • Begay CK, Gandolfi AJ. 2003. Late administration of COX-2 inhibitors minimize hepatic necrosis in chloroform-induced liver injury. Toxicology 185:79-87 (Pubitemid 36050732)
    • (2003) Toxicology , vol.185 , Issue.1-2 , pp. 79-87
    • Begay, C.K.1    Gandolfi, A.J.2
  • 131
    • 0034623266 scopus 로고    scopus 로고
    • Cyclooxygenase-2 participates in the late phase of airway hyperresponsiveness after ozone exposure in guinea pigs
    • Nakano H, Aizawa H, Matsumoto K, Fukuyama S, Inoue H, Hara N. 2000. Cyclooxygenase-2 participates in the late phase of airway hyperresponsiveness after ozone exposure in guinea pigs. Eur. J. Pharmacol. 403:267-75
    • (2000) Eur. J. Pharmacol. , vol.403 , pp. 267-75
    • Nakano, H.1    Aizawa, H.2    Matsumoto, K.3    Fukuyama, S.4    Inoue, H.5    Hara, N.6
  • 132
    • 0021995646 scopus 로고
    • The relation of leukotrienes to liver injury
    • DOI 10.1002/hep.1840050530
    • Keppler D, Hagmann W, Rapp S, Denzlinger C, Koch HK. 1985. The relation of leukotrienes to liver injury. Hepatology 5:883-91 (Pubitemid 15236639)
    • (1985) Hepatology , vol.5 , Issue.5 , pp. 883-891
    • Keppler, D.1    Hagmann, W.2    Rapp, S.3
  • 133
    • 46749115524 scopus 로고    scopus 로고
    • Leukotrienes, antileukotrienes and asthma
    • Montuschi P. 2008. Leukotrienes, antileukotrienes and asthma. Mini Rev. Med. Chem. 8:647-56
    • (2008) Mini Rev. Med. Chem. , vol.8 , pp. 647-56
    • Montuschi, P.1
  • 135
    • 77952861578 scopus 로고    scopus 로고
    • Involvement of leukotrienes in the pathogenesis of silica-induced pulmonary fibrosis in mice
    • Shimbori C, Shiota N, Okunishi H. 2010. Involvement of leukotrienes in the pathogenesis of silica-induced pulmonary fibrosis in mice. Exp. Lung Res. 36:292-301
    • (2010) Exp. Lung Res. , vol.36 , pp. 292-301
    • Shimbori, C.1    Shiota, N.2    Okunishi, H.3
  • 136
    • 0025128659 scopus 로고
    • Leukotriene inhibitors modulate hepatic injury induced by lipopolysaccharide-activated macrophages
    • DOI 10.1016/0168-8278(90)90073-Z
    • Shiratori Y, Tanaka M, Umihara J, Kawase T, Shiina S, Sugimoto T. 1990. Leukotriene inhibitors modulate hepatic injury induced by lipopolysaccharide- activated macrophages. J. Hepatol. 10:51-61 (Pubitemid 20006989)
    • (1990) Journal of Hepatology , vol.10 , Issue.1 , pp. 51-61
    • Shiratori, Y.1    Tanaka, M.2    Umihara, J.3    Kawase, T.4    Shiina, S.5    Sugimoto, T.6
  • 139
    • 33845484030 scopus 로고    scopus 로고
    • Pharmacological inhibition of leukotrienes in an animal model of bleomycin-induced acute lung injury
    • Failla M, Genovese T, Mazzon E, Gili E, Muia C, et al. 2006. Pharmacological inhibition of leukotrienes in an animal model of bleomycin-induced acute lung injury. Respir. Res. 7:137
    • (2006) Respir. Res. , vol.7 , pp. 137
    • Failla, M.1    Genovese, T.2    Mazzon, E.3    Gili, E.4    Muia, C.5
  • 141
    • 77953292881 scopus 로고    scopus 로고
    • The platelet activating factor (PAF) signaling cascade in systemic inflammatory responses
    • Yost CC, Weyrich AS, Zimmerman GA. 2010. The platelet activating factor (PAF) signaling cascade in systemic inflammatory responses. Biochimie 92:692-97
    • (2010) Biochimie , vol.92 , pp. 692-97
    • Yost, C.C.1    Weyrich, A.S.2    Zimmerman, G.A.3
  • 142
    • 0027529360 scopus 로고
    • Platelet-activating factor-induced calcium mobilization and oxidative metabolism in hepatic macrophages and endothelial cells
    • Gardner CR, Laskin JD, Laskin DL. 1993. Platelet-activating factor-induced calcium mobilization and oxidative metabolism in hepatic macrophages and endothelial cells. J. Leukoc. Biol. 53:190-96 (Pubitemid 23100163)
    • (1993) Journal of Leukocyte Biology , vol.53 , Issue.2 , pp. 190-196
    • Gardner, C.R.1    Laskin, J.D.2    Laskin, D.L.3
  • 143
    • 0028951052 scopus 로고
    • Platelet-activating factor mediates the ozone-induced increase in airway microvascular leakage in guinea pigs
    • Kaneko T, Ikeda H, Fu L, Nishiyama H, Okubo T. 1995. Platelet-activating factor mediates the ozone-induced increase in airway microvascular leakage in guinea pigs. Eur. J. Pharmacol. 292:251-55
    • (1995) Eur. J. Pharmacol. , vol.292 , pp. 251-55
    • Kaneko, T.1    Ikeda, H.2    Fu, L.3    Nishiyama, H.4    Okubo, T.5
  • 144
    • 0026707811 scopus 로고
    • The effect of platelet activating factor antagonist on ozone-induced airway inflammation and bronchial hyperresponsiveness in guinea pigs
    • Tan WC, Bethel RA. 1992. The effect of platelet activating factor antagonist on ozone-induced airway inflammation and bronchial hyperresponsiveness in guinea pigs. Am. Rev. Respir. Dis. 146:916-22
    • (1992) Am. Rev. Respir. Dis. , vol.146 , pp. 916-22
    • Tan, W.C.1    Bethel, R.A.2
  • 145
    • 0027219383 scopus 로고
    • Induction of functionally active platelet-activating factor receptors in rat alveolar macrophages
    • Pendino KJ, Gardner CR, Laskin JD, Laskin DL. 1993. Induction of functionally active platelet-activating factor receptors in rat alveolar macrophages. J. Biol. Chem. 268:19165-68 (Pubitemid 23270679)
    • (1993) Journal of Biological Chemistry , vol.268 , Issue.26 , pp. 19165-19168
    • Pendino, K.J.1    Gardner, C.R.2    Laskin, J.D.3    Laskin, D.L.4
  • 146
    • 0025915814 scopus 로고
    • Priming by platelet-activating factor of endotoxin-induced lung injury and cardiovascular shock
    • Rabinovici R, Esser KM, Lysko PG, Yue TL, Griswold DE, et al. 1991. Priming by platelet-activating factor of endotoxin-induced lung injury and cardiovascular shock. Circ. Res. 69:12-25
    • (1991) Circ. Res. , vol.69 , pp. 12-25
    • Rabinovici, R.1    Esser, K.M.2    Lysko, P.G.3    Yue, T.L.4    Griswold, D.E.5
  • 149
    • 38549102077 scopus 로고    scopus 로고
    • TNF-mediated inflammatory disease
    • DOI 10.1002/path.2287
    • Bradley JR. 2008. TNF-mediated inflammatory disease. J. Pathol. 214:149-60 (Pubitemid 351160153)
    • (2008) Journal of Pathology , vol.214 , Issue.2 , pp. 149-160
    • Bradley, J.R.1
  • 153
    • 0025225649 scopus 로고
    • Involvement of tumor necrosis factor-αin development of hepatic injury in galactosamine-sensitized mice
    • Hishinuma I, Nagakawa J, Hirota K, Miyamoto K, Tsukidate K, et al. 1990. Involvement of tumor necrosis factor-αin development of hepatic injury in galactosamine-sensitized mice. Hepatology 12:1187-91
    • (1990) Hepatology , vol.12 , pp. 1187-91
    • Hishinuma, I.1    Nagakawa, J.2    Hirota, K.3    Miyamoto, K.4    Tsukidate, K.5
  • 156
    • 0027212844 scopus 로고
    • Enhanced IL-1β and tumor necrosis factor-α release and messenger RNA expression in macrophages from idiopathic pulmonary fibrosis or after asbestos exposure
    • Zhang Y, Lee TC, Guillemin B, Yu MC, Rom WN. 1993. Enhanced IL-1β and tumor necrosis factor-α release and messenger RNA expression in macrophages from idiopathic pulmonary fibrosis or after asbestos exposure. J. Immunol. 150:4188-96 (Pubitemid 23129800)
    • (1993) Journal of Immunology , vol.150 , Issue.9 , pp. 4188-4196
    • Zhang, Y.1    Lee, T.C.2    Guillemin, B.3    Yu, M.-C.4    Rom, W.N.5
  • 157
    • 39849092094 scopus 로고    scopus 로고
    • Regulation of caveolin-1 expression, nitric oxide production and tissue injury by tumor necrosis factor-α following ozone inhalation
    • Fakhrzadeh L, Laskin JD, Laskin DL. 2008. Regulation of caveolin-1 expression, nitric oxide production and tissue injury by tumor necrosis factor-α following ozone inhalation. Toxicol. Appl. Pharmacol. 227:380-89
    • (2008) Toxicol. Appl. Pharmacol. , vol.227 , pp. 380-89
    • Fakhrzadeh, L.1    Laskin, J.D.2    Laskin, D.L.3
  • 158
    • 0029015685 scopus 로고
    • Prevention of carbon tetrachloride-induced rat liver injury by soluble tumor necrosis factor receptor
    • Czaja MJ, Xu J, Alt E. 1995. Prevention of carbon tetrachloride-induced rat liver injury by soluble tumor necrosis factor receptor. Gastroenterology 108:1849-54
    • (1995) Gastroenterology , vol.108 , pp. 1849-54
    • Czaja, M.J.1    Xu, J.2    Alt, E.3
  • 160
    • 0025211892 scopus 로고
    • Requirement of tumour necrosis factor for development of silica-induced pulmonary fibrosis
    • Piguet PF, Collart MA, Grau GE, Sappino AP, Vassalli P. 1990. Requirement of tumour necrosis factor for development of silica-induced pulmonary fibrosis. Nature 344:245-47
    • (1990) Nature , vol.344 , pp. 245-47
    • Piguet, P.F.1    Collart, M.A.2    Grau, G.E.3    Sappino, A.P.4    Vassalli, P.5
  • 162
    • 41549108565 scopus 로고    scopus 로고
    • Inhibition of the tumor necrosis factor-α pathway is radioprotective for the lung
    • DOI 10.1158/1078-0432.CCR-07-1894
    • Zhang M, Qian J, Xing X, Kong FM, Zhao L, et al. 2008. Inhibition of the tumor necrosis factor-a pathway is radioprotective for the lung. Clin. Cancer Res. 14:1868-76 (Pubitemid 351469474)
    • (2008) Clinical Cancer Research , vol.14 , Issue.6 , pp. 1868-1876
    • Zhang, M.1    Qian, J.2    Xing, X.3    Kong, F.-M.4    Zhao, L.5    Chen, M.6    Lawrence, T.S.7
  • 164
    • 63349099346 scopus 로고    scopus 로고
    • The role of interleukin-113 in murine cigarette smoke-induced emphysema and small airway remodeling
    • Churg A, Zhou S, Wang X, Wang R, Wright JL. 2009. The role of interleukin-113 in murine cigarette smoke-induced emphysema and small airway remodeling. Am. J. Respir. CellMol. Biol. 40:482-90
    • (2009) Am. J. Respir. CellMol. Biol. , vol.40 , pp. 482-90
    • Churg, A.1    Zhou, S.2    Wang, X.3    Wang, R.4    Wright, J.L.5
  • 166
    • 0033665578 scopus 로고    scopus 로고
    • Treatment with neutralising antibody against cytokine induced neutrophil chemoattractant (CINC) protects rats against acute pancreatitis associated lung injury
    • Bhatia M, Brady M, Zagorski J, Christmas SE, Campbell F, et al. 2000. Treatment with neutralising antibody against cytokine induced neutrophil chemoattractant (CINC) protects rats against acute pancreatitis associated lung injury. Gut 47:838-44
    • (2000) Gut , vol.47 , pp. 838-44
    • Bhatia, M.1    Brady, M.2    Zagorski, J.3    Christmas, S.E.4    Campbell, F.5
  • 167
    • 0037281863 scopus 로고    scopus 로고
    • The inflammatory macrophage: A story of Jekyll and Hyde
    • DOI 10.1042/CS20020240
    • Duffield JS. 2003. The inflammatory macrophage: a story of Jekyll and Hyde. Clin. Sci. 104:27-38 (Pubitemid 36249921)
    • (2003) Clinical Science , vol.104 , Issue.1 , pp. 27-38
    • Duffield, J.S.1
  • 168
    • 56149103896 scopus 로고    scopus 로고
    • Macrophage polarization in bacterial infections
    • Benoit M, Desnues B, Mege JL. 2008. Macrophage polarization in bacterial infections. J. Immunol. 181:3733-39
    • (2008) J. Immunol. , vol.181 , pp. 3733-39
    • Benoit, M.1    Desnues, B.2    Mege, J.L.3
  • 169
    • 42649089790 scopus 로고    scopus 로고
    • Resolving inflammation: Dual anti-inflammatory and pro-resolution lipid mediators
    • DOI 10.1038/nri2294, PII NRI2294
    • Serhan CN, Chiang N, Van Dyke TE. 2008. Resolving inflammation: dual anti-inflammatory and pro-resolution lipid mediators. Nat. Rev. Immunol. 8:349-61 (Pubitemid 351595216)
    • (2008) Nature Reviews Immunology , vol.8 , Issue.5 , pp. 349-361
    • Serhan, C.N.1    Chiang, N.2    Van Dyke, T.E.3
  • 170
    • 11444261543 scopus 로고    scopus 로고
    • 15d-PGJ2: The anti-inflammatory prostaglandin?
    • Scher JU, Pillinger MH. 2005. 15d-PGJ2: the anti-inflammatory prostaglandin? Clin. Immunol. 114:100-9
    • (2005) Clin. Immunol. , vol.114 , pp. 100-9
    • Scher, J.U.1    Pillinger, M.H.2
  • 171
    • 17644405062 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-γ is a new therapeutic target in sepsis and inflammation
    • DOI 10.1097/01.shk.0000160521.91363.88
    • Zingarelli B, CookJA. 2005. Peroxisome proliferator-activated receptor-y is a new therapeutic target in sepsis and inflammation. Shock 23:393-99 (Pubitemid 40571660)
    • (2005) Shock , vol.23 , Issue.5 , pp. 393-399
    • Zingarelli, B.1    Cook, J.A.2
  • 172
    • 24344510350 scopus 로고    scopus 로고
    • Anti-inflammatory circuitry: Lipoxin, aspirin-triggered lipoxins and their receptor ALX
    • DOI 10.1016/j.plefa.2005.05.003, PII S0952327805000815
    • Chiang N, Arita M, Serhan CN. 2005. Anti-inflammatory circuitry: lipoxin, aspirin-triggered lipoxins and their receptor ALX. Prostaglandins Leukot. Essent. Fatty Acids 73:163-77 (Pubitemid 41253473)
    • (2005) Prostaglandins Leukotrienes and Essential Fatty Acids , vol.73 , Issue.3-4 , pp. 163-177
    • Chiang, N.1    Arita, M.2    Serhan, C.N.3
  • 173
    • 24344469198 scopus 로고    scopus 로고
    • Lipoxins and lipoxin analogs in asthma
    • DOI 10.1016/j.plefa.2005.05.010, PII S0952327805000888
    • Levy BD. 2005. Lipoxins and lipoxin analogs in asthma. Prostaglandins Leukot. Essent. Fatty Acids 73:231-37 (Pubitemid 41253480)
    • (2005) Prostaglandins Leukotrienes and Essential Fatty Acids , vol.73 , Issue.3-4 , pp. 231-237
    • Levy, B.D.1
  • 174
    • 40349100270 scopus 로고    scopus 로고
    • Endogenous pro-resolving and anti-inflammatory lipid mediators: A new pharmacologic genus
    • DOI 10.1038/sj.bjp.0707489, PII 0707489
    • Serhan CN, Chiang N 2008. Endogenous pro-resolving and anti-inflammatory lipid mediators: a new pharmacologic genus. Br. J. Pharmacol. 153(Suppl. 1):S200-15 (Pubitemid 351340979)
    • (2008) British Journal of Pharmacology , vol.153 , Issue.SUPPL. 1
    • Serhan, C.N.1    Chiang, N.2
  • 175
    • 33845627683 scopus 로고    scopus 로고
    • Docosahexaenoic acid (DHA) blunts liver injury by conversion to protective lipid mediators: Protectin D 1 and 17S-hydroxy-DHA
    • Gonzalez-Periz A, Planaguma A, Gronert K, Miquel R, Lopez-Parra M, et al. 2006. Docosahexaenoic acid (DHA) blunts liver injury by conversion to protective lipid mediators: protectin D 1 and 17S-hydroxy-DHA. FASEBJ. 20:2537-39
    • (2006) FASEBJ. , vol.20 , pp. 2537-39
    • Gonzalez-Periz, A.1    Planaguma, A.2    Gronert, K.3    Miquel, R.4    Lopez-Parra, M.5
  • 176
    • 44349154885 scopus 로고    scopus 로고
    • Modulation of pulmonary inflammatory responses and antimicrobial defenses in mice exposed to diesel exhaust
    • Gowdy K, Krantz QT, Daniels M, Linak WP, Jaspers I, Gilmour MI. 2008. Modulation of pulmonary inflammatory responses and antimicrobial defenses in mice exposed to diesel exhaust. Toxicol. Appl. Pharmacol. 229:310-19
    • (2008) Toxicol. Appl. Pharmacol. , vol.229 , pp. 310-19
    • Gowdy, K.1    Krantz, Q.T.2    Daniels, M.3    Linak, W.P.4    Jaspers, I.5    Gilmour, M.I.6
  • 177
    • 34247121103 scopus 로고    scopus 로고
    • Increased hyperoxia-induced mortality and acute lung injury in IL-13 null mice
    • Bhandari V, Choo-WingR, Homer RJ, EliasJA. 2007. Increased hyperoxia-induced mortality and acute lung injury in IL-13 null mice. J. Immunol. 178:4993-5000 (Pubitemid 46595282)
    • (2007) Journal of Immunology , vol.178 , Issue.8 , pp. 4993-5000
    • Bhandari, V.1    Choo-Wing, R.2    Homer, R.J.3    Elias, J.A.4
  • 178
    • 33646036421 scopus 로고    scopus 로고
    • Regulation of interleukin IL-4, IL-13, IL-10, and their downstream components in lipopolysaccharide-exposed rat lungs: Comparison of the constitutive expression between rats and humans
    • Hocke AC, Ermert M, Althoff A, Brell B, NGuessan PD, et al. 2006. Regulation of interleukin IL-4, IL-13, IL-10, and their downstream components in lipopolysaccharide-exposed rat lungs: comparison of the constitutive expression between rats and humans. Cytokine 33:199-211
    • (2006) Cytokine , vol.33 , pp. 199-211
    • Hocke, A.C.1    Ermert, M.2    Althoff, A.3    Brell, B.4    Nguessan, P.D.5
  • 179
    • 51249120776 scopus 로고    scopus 로고
    • Identification of transforming growth factor α31-driven genetic programs of acute lung fibrosis
    • Pulichino AM, Wang IM, Caron A, Mortimer J, Auger A, et al. 2008. Identification of transforming growth factor α31-driven genetic programs of acute lung fibrosis. Am. J. Respir. CellMol. Biol. 39:324-36
    • (2008) Am. J. Respir. CellMol. Biol. , vol.39 , pp. 324-36
    • Pulichino, A.M.1    Wang, I.M.2    Caron, A.3    Mortimer, J.4    Auger, A.5
  • 181
    • 23844531047 scopus 로고    scopus 로고
    • 3) on the appearance of macrophage populations and fibrogenesis in thioacetamide-induced rat hepatic lesions
    • DOI 10.1016/j.jcpa.2005.01.011, PII S0021997505000289
    • 3) on the appearance of macrophage populations and fibrogenesis in thioacetamide-induced rat hepatic lesions. J. Comp. Pathol. 133:92-102 (Pubitemid 41150166)
    • (2005) Journal of Comparative Pathology , vol.133 , Issue.2-3 , pp. 92-102
    • Ide, M.1    Kuwamura, M.2    Kotani, T.3    Sawamoto, O.4    Yamate, J.5
  • 184
    • 36048981853 scopus 로고    scopus 로고
    • Role of TLR-4 in liver macrophage and endothelial cell responsiveness during acute endotoxemia
    • DOI 10.1016/j.yexmp.2007.08.015, PII S0014480007001104
    • Chen LC, Gordon RE, Laskin JD, Laskin DL. 2007. Role of TLR-4 in liver macrophage and endothelial cell responsiveness during acute endotoxemia. Exp. Mol. Pathol. 83:311-26 (Pubitemid 350087034)
    • (2007) Experimental and Molecular Pathology , vol.83 , Issue.3 , pp. 311-326
    • Chen, L.C.1    Gordon, R.E.2    Laskin, J.D.3    Laskin, D.L.4
  • 185
    • 1542345003 scopus 로고    scopus 로고
    • Effects of lipopolysaccharides stimulated Kupffer cells on activation of rat hepatic stellate cells
    • Zhang X, Yu WP, Gao L, Wei KB, Ju JL, Xu JZ. 2004. Effects of lipopolysaccharides stimulated Kupffer cells on activation of rat hepatic stellate cells. World J. Gastroenterol. 10:610-13 (Pubitemid 38325326)
    • (2004) World Journal of Gastroenterology , vol.10 , Issue.4 , pp. 610-613
    • Zhang, X.1    Yu, W.-P.2    Gao, L.3    Wei, K.-B.4    Ju, J.-L.5    Xu, J.-Z.6


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