Pulmonary toxicity of well-dispersed multi-wall carbon nanotubes following inhalation and intratracheal instillation

Nanotoxicology

Volumn 6, Issue 6, 2012, Pages 587-599

  Morimoto, Yasuo ^a   Hirohashi, Masami ^a   Ogami, Akira ^a   Oyabu, Takako ^a   Myojo, Toshihiko ^a   Todoroki, Motoi ^a   Yamamoto, Makoto ^a   Hashiba, Masayoshi ^a   Mizuguchi, Yohei ^a   Lee, Byeong Woo ^a   Kuroda, Etsushi ^a   Shimada, Manabu ^b   Wang, Wei Ning ^b   Yamamoto, Kazuhiro ^c   Fujita, Katsuhide ^c   Endoh, Shigehisa ^c   Uchida, Kunio ^c   Kobayashi, Norihiro ^c   Mizuno, Kohei ^c   Inada, Masaharu ^c   Tao, Hiroaki ^c   Nakazato, Tetsuya ^c   Nakanishi, Junko ^c   Tanaka, Isamu ^a   more..

^a UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

^b HIROSHIMA UNIVERSITY   (Japan)

^c NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

Author keywords

Carbon nanotube; Dispersion; Inhalation; Intratracheal instillation; Nanomaterial

Indexed keywords

ALKALINE PHOSPHATASE; CYTOKINE INDUCED NEUTROPHIL CHEMOATTRACTANT; CYTOKINE INDUCED NEUTROPHIL CHEMOATTRACTANT 1; CYTOKINE INDUCED NEUTROPHIL CHEMOATTRACTANT 2; CYTOKINE INDUCED NEUTROPHIL CHEMOATTRACTANT 3; MULTI WALLED NANOTUBE; MYELOPEROXIDASE; UNCLASSIFIED DRUG; ALPHA CHEMOKINE; CARBON NANOTUBE; PEROXIDASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME RELEASE; HISTOPATHOLOGY; INHALATION; LUNG ALVEOLUS MACROPHAGE; LUNG GRANULOMATOSIS; LUNG TOXICITY; MALE; NEUTROPHIL; NEUTROPHIL CHEMOTAXIS; NEUTROPHIL COUNT; NONHUMAN; PARTICLE SIZE; PNEUMONIA; PRIORITY JOURNAL; RAT; TRANSMISSION ELECTRON MICROSCOPY; ANIMAL; CHEMISTRY; CYTOLOGY; DRUG EFFECT; INHALATIONAL DRUG ADMINISTRATION; LUNG; LUNG LAVAGE; METABOLISM; NONPARAMETRIC TEST; PATHOLOGY; TOXICITY TESTING; WISTAR RAT;

ADMINISTRATION, INHALATION; ALKALINE PHOSPHATASE; ANIMALS; BRONCHOALVEOLAR LAVAGE FLUID; CHEMOKINES, CXC; LUNG; MACROPHAGES, ALVEOLAR; MALE; NANOTUBES, CARBON; PEROXIDASE; RATS; RATS, WISTAR; STATISTICS, NONPARAMETRIC; TOXICITY TESTS;

EID: 84870678346     PISSN: 17435390     EISSN: 17435404     Source Type: Journal    
DOI: 10.3109/17435390.2011.594912     Document Type: Article

References (45)

1. Bide RW, Armour SJ, Yee R. 2000. Allometric respiration/body mass date for animals to be used for estimates of inhalation toxicity to young and adult humans. J Appl Toxicol 20:273-290 (Pubitemid 30601407)
2. Borm PJA, Driscoll K. 1996. Particles, inflammation and respiratory tract carcinogenesis. Toxicol Lett 88(1):109-113 (Pubitemid 26361255)
3. Card JW, Zeldin DC, Bonner JC, Nestmann ER. 2008. Pulmonary applications and toxicology of engineered nanoparticles. Am J Physiol Lung Cell Mol Physiol 295:L400-411
4. Darsono N, Yoon D-H, Kim J. 2008. Milling and dispersion of multiwalled carbon nanotubes in texanol. Appl Sur Sci 254:3412-3419
5. Dillon AC, Parilla PA, Alleman JL, Gennett T, Jones KM, Heben MJ. 2005. Systematic inclusion of defects in pure carbon single-wall nanotubes and their effect on the Raman D-band. Chem Phys Lett 401:522-528 (Pubitemid 40038298)
6. Dresselhaus MS, Dresselhaus G, Saito R, Jorio A. 2005. Raman spectroscopy of carbon nanotubes. Phys Rep 409:47-99 (Pubitemid 40317386)
7. Endo M. 1988. Grow carbon fibers in the vapor phase. Chem Tech 18:568-576
8. Fujita K, Morimoto Y, Ogami A, Tanaka I, Endoh S, Uchida K, Tao H, Akasaka M, Inada M, Yamamoto K, Fukui H, Hayakawa M, Horie M, Saito Y, Yoshida Y, Iwahashi H, Niki E, Nakanishi J. 2009. A gene expression profiling approach to study the influence of ultrafine particles on rat lungs. In: Kim JY, Platt U, Gu MB, Iwahashi H, editors. Atmospheric and biological environmental monitoring. Dordrecht: Springer Netherlands, pp. 219-227
9. Han JH, Lee EJ, So KP, Lee YH, Bae GN, Lee SB, Ji JH, Cho MH, Yu IJ. 2008. Monitoring multiwalled carbon nanotube in carbon nanotube research facility. Inhal Toxicol 20:741-749 (Pubitemid 351882937)
10. Iijima S. 1991. Helical microtubes of graphitic carbon. Nature 354:56-58
11. Johnson DR, Methner MM, Kennedy AJ, Steevens JA. 2010. Potential for occupational exposure to engineered carbon-based nanomaterials in environmental laboratory studies. Environ Health Perspect 118:49-54
12. Kobayashi N, Naya M, Endoh S, Maru J, Yamamoto K, Nakanishi J. 2009. Comparative pulmonary toxicity study of nano-TiO2 particles of different sizes and agglomerations in rats: Different short-and long-term post-instillation results. Toxicology 264:110-118
13. Kobayashi N, Naya M, Ema M, Endoh S, Maru J, Mizuno K, Nakanishi J. 2010. Biological response and morphological assessment of individually dispersed multi-wall carbon nanotubes in the lung after intratracheal instillation in rats. Toxicology 276:143-153
14. Kreyling WG, Semmler-Behnke M, Seitz J, Scymczak W, Wenk A, Mayer P, Takenaka S, Oberdörster G. 2009. Size dependence of the translocation of inhaled iridium and carbon nanoparticles aggregates from the lung of rats to the blood and secondary target organs Inhal Toxicol 21(S1):55-60
15. Lam CW, James JT, McCluskey R, Hunter RL. 2004 Pulmonary toxicity of single-wall carbon nanotubes in mice 7 and 90 days after intratracheal instillation. Toxicol. Sci 77:126-134 (Pubitemid 38128652)
16. Lee S, Peng W Jr, Liu C-H. 2008. Raman study of carbon nanotube purification using atmospheric pressure plasma. Carbon 46:2124-2132
17. Liu S, Wei L, Hao L, Fang N, Chang M-W, Xu R, Yang Y, Chen Y. 2009. Sharper and faster "nano darts" kill more bacteria. A study of antibacterial activity of individually dispersed pristine single-walled carbon nanotube. ACS Nano 3:3891-3902
18. Ma-Hock L, Treumann S, Strauss V, Brill S, Luizi F, Mertler M, Wiench K, Gamer AO, van Ravenzwaay B, Landsiedel R. 2009 Inhalation toxicity of multi-wall carbon nanotubes in rats exposed for 3 months. Toxicol Sci 112:468-481
19. Mercer RR, Scabilloni J, Wang L, Kisin E, Murray AR, Schwegler-Berry D, Shvedova AA, Castranova V. 2008. Alteration of deposition pattern and pulmonary response as a result of improved dispersion of aspirated single walled carbon nanotubes in a mouse model. Am J Physiol Lung Cell Mol Physiol 294:87-97
20. Miller FJ. 2000. Dosimetry of particles in laboratory animals and humans in relationship to issues surrounding lung overload and human health risk assessment: A critical review. Inhal Toxicol 12:19-57 (Pubitemid 30081163)
21. Mitchell LA, Gao J, Wal RV, Gigliotti A, Burchiel SW, McDonald JD. 2007. Pulmonary and systemic immune response to inhaled multiwalled carbon nanotubes. Toxicol Sci 100(1):203-214 (Pubitemid 47617817)
22. Mitsuhashi H, Hata J, Asano S, Kishimoto T. 1999. Apperarance ofcytokine-inducedneutrophilchemoattractant isoforoms andimmunolocalization of them in lipopolysaccharide-induced acute lung inflammation in rats. Inflammation Res 48:588-593
23. Morimoto Y, Kobayashi N, Shinohara N, Myojo T, Tanaka I, Nakanishi J. 2010a. Hazard assessments of manufactured nanomaterials. J Occup Health 52(6):325-334
24. Morimoto Y, Hirohashi M, Ogami A, Oyabu T, Myojo T, Nishi K, Kadoya C, Todoroki M, Yamamoto M, Murakami M, Shimada M, Wang WN,Yamamoto K, Fujita K, Endoh S, Uchida K, Shinohara N, Nakanishi J, Tanaka I. 2010b. Inflammogenic effect of wellcharacterized fullerenes in inhalation and intratracheal instillation studies. Part Fibre Toxicol 7:4
25. Morimoto Y, Ogami A, Todoroki M, Yamamoto M, Murakami M, Hirohashi M, Oyabu T, Myojo T, Nishi K, Kadoya C, Yamasaki S, Nagatomo H, Tanaka I, Fujita K, Endoh S, Uchida K, Yamamoto K, Kobayashi N, Nakanishi J. 2010c. Expression of inflammation-related cytokines following intratracheal instillation of nickel oxide nanoparticles. Nanotoxicology 4(2):161-176
26. Muller J, Huaux F, Moreau N, Misson P, Heilier JF, Delos M, Arras M, Fonseca A, Nagy JB, Lison D. 2005. Respiratory toxicity of multi-wall carbon nanotubes. Toxicol Appl Pharmacol 207:221-231 (Pubitemid 41207915)
27. Muller J, Huaux F, Fonseca A, Nagy JB, Moreau N, Delos M, Raymundo-Piñero E, Béguin F, Kirsch-Volders M, Fenoglio I, Fubini B, Lison D. 2008a. Structural defects play a major role in the acute lung toxicity of multiwall carbon nanotubes: Physicochemical aspects. Chem Res Toxicol 21 (9):1690-1697
28. Muller J, Huaux F, Fonseca A, Nagy JB, Moreau N, Delos M, Raymundo-Piñero E, Béguin F, Kirsch-Volders M, Fenoglio I, Fubini B, Lison D. 2008b. Structural defects play a major role in the acute lung toxicity of multiwall carbon nanotubes: Toxicological aspects. Chem Res Toxicol 21(9):1698-1705
29. Muller J, Delos M, Panin N, Rabolli V, Huaux F, Lison D. 2009. Absence of carcinogenic response to multiwall carbon nanotubes in a 2-year bioassay in the peritoneal cavity of the rat. Toxicol Sci 110:442-448
30. Musumeci AW, Waclawik ER, Frost RL. 2008. A comparative study of single-walled carbon nanotube purification techniques using Raman spectroscopy. Spectrochim Acta Part A 71:140-142
31. Mutlu GM, Budinger GR, Green AA, Urich D, Soberanes S, Chiarella SE, Alheid GF, McCrimmon DR, Szleifer I, Hersam MC. 2010. Biocompatible nanoscale dispersion of single-walled carbon nanotubes minimizes in vivo pulmonary toxicity. Nano Lett 10 (5):1664-1670
32. Nishi K, Morimoto Y, Ogami A, Murakami M, Myojo T, Oyabu T, Kadoya C, Yamamoto M, Todoroki M, Hirohashi M, Yamasaki S, Fujita K, Endo S, Uchida K, Nakanishi J and Tanaka I. 2009. Expression of cytokine-induced neutrophil chemoattractant in rat lungs by intratracheal instillation of nickel oxide nanoparticles. Inhal Toxicol 21(12):1030-1039
33. Oberdörster G, Oberdörster E, Oberdörster J. 2005. Nanotoxicology: An emerging discipline evolving from studies of ultrafine particles. Environ Health Perspect 113:823-839 (Pubitemid 40984181)
34. Pacurari M, Yin XJ, Ding M, Leonard SS, Schwegler-Berry D, Ducatman BS, Chirila M, Endo M, Castranova V, Vallyathan V. 2008 Oxidative and molecular interactions of multi-wall carbon nanotubes (MWCNT) in normal and malignant human mesothelial cells. Nanotoxicology 2(3):155-170
35. Pauluhn J. 2010. Subchronic 13-week inhalation exposure of rats to multiwalled carbon nanotubes: Toxic effects are determined by density of agglomerate structures, not fibrillar structures. Toxicol Sci 113:226-242
36. Poland CA, Duffin R, Kinloch I, Maynard A, Wallace WAH, Seaton A, Stone V, Brown S, MacNee W, Donaldson K. 2008. Carbon nanotubes introduced into the abdominal cavity of mice show asbestoslike pathogenicity in a pilot study. Nat Nanotechnol 3:423-428
37. Rutishauser BR, Brown DM, Boyles MP, Kinloch IA, Windle AH, Gehr P, Stone V. 2010. Relating the physicochemical characteristics and dispersion of multiwalled carbon nanotubes in different suspension media to their oxidative reactivity in vitro and inflammation in vivo. Nanotoxicology 4(3):331-342
38. Sayes CM, Reed KL, Warheit DB. 2007. Assessing toxicity of fine and nanoparticles: Comparing in vitro measurements to in vivo pulmonary toxicity profiles. Toxicol Sci 97(1):163-180 (Pubitemid 47072165)
39. Shacter E, Weitzman SA. 2002. Chronic inflammation and cancer. Oncology 16:217-232
40. Shvedova AA, Kisin ER, Mercer R, Murray AR, Johnson VJ, Potapovich AI, Tyurina YY, Gorelik O, Arepalli S, Schwegler-Berry D, Hubbs AF, Antonini J, Evans DE, Ku BK, Ramsey D, Maynard A, Kagan VE, Castronova V, Baron P. 2005 Unusual inflammatory and fibrogenic pulmonary responses to single-walled carbon nanotubes in mice. Am J Physiol Lung Cell Mol Physiol 289(5):L696-708
41. Vankoningsloo S, Piret JP, Saout C, Noel F, Mejia J, Zouboulis CC, Delhalle J, Lucas S, Tousaint O. 2010. Cytotoxicity of multi-walled carbon nanotubes in three skin cellular models: Effects of sonication, dispersive agents and corneous layer of reconstructed epidermis. Nanotoxicology 4(1):84-97
42. Wang L, Castranova V, Mishra A, Chen B, Mercer RR, Schwegler-Berry D, Rojanasakul Y. 2010. Dispersion of single-walled carbon nanotubes by a natural lung surfactant for pulmonary in vitro and in vivo studies. Part Fibre Toxicol 7:31
43. Warheit DB, Laurence BR, Reed KL, Roach DH, Webb TR. 2004. Comparative pulmonary toxicity assessment of single-wall carbon nanotubes in rats. Toxicol Sci 77:117-125 (Pubitemid 38128651)
44. Wepasnick KA, Smith BA, Bitter JL, Fairbrother DH. 2010. Chemical and structural characterization of carbon nanotube surfaces. Anal Bioanal Chem 396:1003-1014
45. Yokota S, Seki T, Furuya M, O'Hara N. 2005. Acute functional enhancement of circulatory neutrophils after intratracheal instillation with diesel exhaust particles in rats. Inhal Toxicol 17 (12):671-679 (Pubitemid 41233162)