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Volumn 13, Issue 6, 1998, Pages 539-555

Comet assay responses as indicators of carcinogen exposure

Author keywords

[No Author keywords available]

Indexed keywords

CARCINOGEN;

EID: 0031755770     PISSN: 02678357     EISSN: None     Source Type: Journal    
DOI: 10.1093/mutage/13.6.539     Document Type: Review
Times cited : (177)

References (245)
  • 1
    • 0031182980 scopus 로고    scopus 로고
    • Photochemical and photobiological studies of a furonaphthopyranone as a benzo-spaced psoralen analog in cell-free and cellular DNA
    • Adam,W. et al, (1997) Photochemical and photobiological studies of a furonaphthopyranone as a benzo-spaced psoralen analog in cell-free and cellular DNA. Photochem. Photobiol., 66, 46-54.
    • (1997) Photochem. Photobiol. , vol.66 , pp. 46-54
    • Adam, W.1
  • 2
    • 0029923890 scopus 로고    scopus 로고
    • Use of the alkaline comet assay to detect DNA repair deficiencies in human fibroblasts exposed to UVC, UVB, UVA and gamma-rays
    • Alapetite,C., Wachter,T., Sage,E. and Moustacchi,E. (1996) Use of the alkaline comet assay to detect DNA repair deficiencies in human fibroblasts exposed to UVC, UVB, UVA and gamma-rays. Int. J. Radiat. Biol., 69, 359-369.
    • (1996) Int. J. Radiat. Biol. , vol.69 , pp. 359-369
    • Alapetite, C.1    Wachter, T.2    Sage, E.3    Moustacchi, E.4
  • 3
    • 0031021024 scopus 로고    scopus 로고
    • The comet assay as a repair test for prenatal diagnosis of Xeroderma pigmentosum and trichothiodystrophy
    • Alapetite,C., Benoit,A., Moustacchi,E. and Sarasin,A. (1997) The comet assay as a repair test for prenatal diagnosis of Xeroderma pigmentosum and trichothiodystrophy. J. Invest. Dermatol., 108, 154-159.
    • (1997) J. Invest. Dermatol. , vol.108 , pp. 154-159
    • Alapetite, C.1    Benoit, A.2    Moustacchi, E.3    Sarasin, A.4
  • 5
    • 0031419247 scopus 로고    scopus 로고
    • In vitro genotoxic effects of hard metal particles assessed by alkaline single cell gel and elution assays
    • Anard,D., Kirsch-Volders,M., Elhajouji,A., Belpaeme,K. and Lison,D. (1997) In vitro genotoxic effects of hard metal particles assessed by alkaline single cell gel and elution assays. Carcinogenesis, 18, 177-184.
    • (1997) Carcinogenesis , vol.18 , pp. 177-184
    • Anard, D.1    Kirsch-Volders, M.2    Elhajouji, A.3    Belpaeme, K.4    Lison, D.5
  • 6
    • 0031982721 scopus 로고    scopus 로고
    • The International Comet Assay Workshop
    • Anderson,D. and Plewa,M.J. (1998) The International Comet Assay Workshop. Mutagenesis, 13, 67-73.
    • (1998) Mutagenesis , vol.13 , pp. 67-73
    • Anderson, D.1    Plewa, M.J.2
  • 7
    • 0028305534 scopus 로고
    • The effect of various antioxidants and other modifying agents on oxygen-radical-generated DNA damage in human lymphocytes in the Comet assay
    • Anderson,D., Yu,T.-W., Phillips,B.J. and Schmezer,P. (1994) The effect of various antioxidants and other modifying agents on oxygen-radical-generated DNA damage in human lymphocytes in the Comet assay. Mutat. Res., 307, 261-271.
    • (1994) Mutat. Res. , vol.307 , pp. 261-271
    • Anderson, D.1    Yu, T.-W.2    Phillips, B.J.3    Schmezer, P.4
  • 8
    • 0029590247 scopus 로고
    • An investigation of the DNA-damaging ability of benzene and its metabolites in human lymphocytes using the comet assay
    • Anderson,D., Yu,T.-W. and Schmezer,P. (1995) An investigation of the DNA-damaging ability of benzene and its metabolites in human lymphocytes using the comet assay. Environ. Mol. Mutagen., 26, 305-314.
    • (1995) Environ. Mol. Mutagen. , vol.26 , pp. 305-314
    • Anderson, D.1    Yu, T.-W.2    Schmezer, P.3
  • 9
    • 0344801351 scopus 로고    scopus 로고
    • An investigation of bone marrow and testicular cells in vivo using the comet assay
    • Anderson,D., Dhawan,A., Yu,T.-W. and Plewa,M.J. (1996) An investigation of bone marrow and testicular cells in vivo using the comet assay. Mutat. Res., 370, 159-174.
    • (1996) Mutat. Res. , vol.370 , pp. 159-174
    • Anderson, D.1    Dhawan, A.2    Yu, T.-W.3    Plewa, M.J.4
  • 10
  • 11
    • 0030863554 scopus 로고    scopus 로고
    • Effect of various genotoxins and reproductive toxins in human lymphocytes and sperm in the comet assay
    • Anderson,D., Dobrzynska,M.M. and Basaran.N. (1997b) Effect of various genotoxins and reproductive toxins in human lymphocytes and sperm in the comet assay. Teratogen. Carcinogen. Mutagen., 17, 29-43.
    • (1997) Teratogen. Carcinogen. Mutagen. , vol.17 , pp. 29-43
    • Anderson, D.1    Dobrzynska, M.M.2    Basaran, N.3
  • 12
    • 3643133352 scopus 로고    scopus 로고
    • Flavonoids modulate comet assay responses to food mutagens in human lymphocytes and sperm
    • in press
    • Anderson,D., Dobrzynska,M.M., Basaran,N., Basaran,A.A. and Yu,T.-W. (1997c) Flavonoids modulate comet assay responses to food mutagens in human lymphocytes and sperm. Mutat. Res., in press.
    • (1997) Mutat. Res.
    • Anderson, D.1    Dobrzynska, M.M.2    Basaran, N.3    Basaran, A.A.4    Yu, T.-W.5
  • 13
    • 0343632383 scopus 로고    scopus 로고
    • Somatic and germ cell effects in rats and mice after treatment with 1.3-butadiene and its metabolites, 1,2-epoxybutene and 1,2,3,4-diepoxybutane
    • Anderson,D., Dobrzynska,M.M., Jackson,L.I., Tu,T.-W. and Brinkworth,M.H. (1997d) Somatic and germ cell effects in rats and mice after treatment with 1.3-butadiene and its metabolites, 1,2-epoxybutene and 1,2,3,4-diepoxybutane. Mutat. Res., 391, 233-242.
    • (1997) Mutat. Res. , vol.391 , pp. 233-242
    • Anderson, D.1    Dobrzynska, M.M.2    Jackson, L.I.3    Tu, T.-W.4    Brinkworth, M.H.5
  • 14
    • 0030783194 scopus 로고    scopus 로고
    • Modulating effects of silymarin and myrectin on food mutagens and doxorubicin in assays with different genetic endpoints
    • Anderson,D., Dobrzynska,M.M. and Yu,T.-W. (1997e) Modulating effects of silymarin and myrectin on food mutagens and doxorubicin in assays with different genetic endpoints. J. Environ. Pathol. Toxicol. Oncol., 16, 313-327.
    • (1997) J. Environ. Pathol. Toxicol. Oncol. , vol.16 , pp. 313-327
    • Anderson, D.1    Dobrzynska, M.M.2    Yu, T.-W.3
  • 16
    • 0030859382 scopus 로고    scopus 로고
    • The effects of vitamin C supplementation on biomarkers of oxygen radical generated damage in human volunteers with 'low' or 'high' cholesterol levels
    • Anderson,D., Phillips,B.J., Yu,T.-W., Edwards,A.J., Ayesh,R. and Butterworth,K.R. (1997g) The effects of vitamin C supplementation on biomarkers of oxygen radical generated damage in human volunteers with 'low' or 'high' cholesterol levels. Environ. Mol. Mutagen., 30, 161-174.
    • (1997) Environ. Mol. Mutagen. , vol.30 , pp. 161-174
    • Anderson, D.1    Phillips, B.J.2    Yu, T.-W.3    Edwards, A.J.4    Ayesh, R.5    Butterworth, K.R.6
  • 17
    • 0030943056 scopus 로고    scopus 로고
    • The use of the same image analysis system to detect genetic damage in human lymphocytes treated with doxorubicin in the Comet and fluoresence in situ hybridisation (FISH) assays
    • Anderson,D., Yu,T.-W. and Brown,M.A. (1997h) The use of the same image analysis system to detect genetic damage in human lymphocytes treated with doxorubicin in the Comet and fluoresence in situ hybridisation (FISH) assays. Mutat. Res., 390, 69-77.
    • (1997) Mutat. Res. , vol.390 , pp. 69-77
    • Anderson, D.1    Yu, T.-W.2    Brown, M.A.3
  • 19
    • 0032574314 scopus 로고    scopus 로고
    • An examination of DNA strand breakage in the comet assay and antioxidant capacity in diabetic patients
    • Anderson,D., Yu,T.-W., Wright,J. and Ioannides,C. (1997j) An examination of DNA strand breakage in the comet assay and antioxidant capacity in diabetic patients. Mutat. Res., 398, 151-161.
    • (1997) Mutat. Res. , vol.398 , pp. 151-161
    • Anderson, D.1    Yu, T.-W.2    Wright, J.3    Ioannides, C.4
  • 20
    • 0030987923 scopus 로고    scopus 로고
    • Detection of DNA damage in human lymphocytes by alkaline single cell electrophoresis after exposure to benzene or benzene metabolites
    • Andreoli,C., Leopardi,P. and Crebelli,R. (1997) Detection of DNA damage in human lymphocytes by alkaline single cell electrophoresis after exposure to benzene or benzene metabolites. Mutat. Res., 377, 95-104.
    • (1997) Mutat. Res. , vol.377 , pp. 95-104
    • Andreoli, C.1    Leopardi, P.2    Crebelli, R.3
  • 21
    • 0006286604 scopus 로고
    • In vitro DNA damage in peripheral blood leukocytes as measured by the single cell gel (SCG) assay
    • Andrews,P.W., Tice,R.R. and Nauman,C.H. (1990) In vitro DNA damage in peripheral blood leukocytes as measured by the single cell gel (SCG) assay. Environ. Mol. Mutagen., 15 (suppl. 17), 6.
    • (1990) Environ. Mol. Mutagen. , vol.15 , Issue.17 SUPPL. , pp. 6
    • Andrews, P.W.1    Tice, R.R.2    Nauman, C.H.3
  • 22
    • 3643141775 scopus 로고
    • DNA damage in normal and choline deficient male B6C3F1 mice treated by oral gavage with fly ash
    • Andrews,P.W., Tice,R.R., Schmitt,M.T.W. and Yager,J.W. (1994) DNA damage in normal and choline deficient male B6C3F1 mice treated by oral gavage with fly ash. Environ. Mol. Mutagen., 23 (suppl. 23), 2.
    • (1994) Environ. Mol. Mutagen. , vol.23 , Issue.23 SUPPL. , pp. 2
    • Andrews, P.W.1    Tice, R.R.2    Schmitt, M.T.W.3    Yager, J.W.4
  • 24
    • 0028910894 scopus 로고
    • The single cell gel electrophoresis assay for induced DNA damage (comet assay) measurement of tail length and moment
    • Ashby,J., Tinwell,H., Lefevre,P.A. and Browne,M.A. (1995) The single cell gel electrophoresis assay for induced DNA damage (comet assay) measurement of tail length and moment. Mutagenesis, 10, 85-90.
    • (1995) Mutagenesis , vol.10 , pp. 85-90
    • Ashby, J.1    Tinwell, H.2    Lefevre, P.A.3    Browne, M.A.4
  • 25
    • 0029778798 scopus 로고    scopus 로고
    • Evaluation of the potential carcinogenicity and genetic toxicity to humans of the herbicide acetochlor
    • Ashby,J., Kier,L., Wilson,A.G., Green,T., Lefevre,P.A., Tinwell,H. and Willis,G.A. (1996) Evaluation of the potential carcinogenicity and genetic toxicity to humans of the herbicide acetochlor. Hum. Exp. Toxicol., 15, 702-735.
    • (1996) Hum. Exp. Toxicol. , vol.15 , pp. 702-735
    • Ashby, J.1    Kier, L.2    Wilson, A.G.3    Green, T.4    Lefevre, P.A.5    Tinwell, H.6    Willis, G.A.7
  • 26
    • 0028834462 scopus 로고
    • Anti-human cytomegalovirus activity and toxicity of sulfonated anthraquinones and anthraquinone derivatives
    • Barnard,D.L., Fairbairn,D.W., O'Neill,K.L., Gage,T.L. and Sidwell,R.W. (1995) Anti-human cytomegalovirus activity and toxicity of sulfonated anthraquinones and anthraquinone derivatives. Antiviral Res., 28, 317-329.
    • (1995) Antiviral Res. , vol.28 , pp. 317-329
    • Barnard, D.L.1    Fairbairn, D.W.2    O'Neill, K.L.3    Gage, T.L.4    Sidwell, R.W.5
  • 27
    • 0344369644 scopus 로고    scopus 로고
    • An investigation of some Turkish herbal medicines in Salmonella typhimurium and in the Comet assay in human lymphocytes
    • Basaran,A.A., Yu,T.-W., Plewa,M.J. and Anderson,D. (1996) An investigation of some Turkish herbal medicines in Salmonella typhimurium and in the Comet assay in human lymphocytes. Teratogen. Carcinogen. Mutatgen., 16, 125-138.
    • (1996) Teratogen. Carcinogen. Mutatgen. , vol.16 , pp. 125-138
    • Basaran, A.A.1    Yu, T.-W.2    Plewa, M.J.3    Anderson, D.4
  • 28
    • 0028862918 scopus 로고
    • Styrene oxide-induced HPRT mutations, DNA adducts and DNA strand breaks in cultured human lymphocytes
    • Bastlova,T., Vodicka,P., Peterkova,K., Hemminki,K. and Lambert,B. (1995) Styrene oxide-induced HPRT mutations, DNA adducts and DNA strand breaks in cultured human lymphocytes. Carcinogenesis, 16, 2357-2362.
    • (1995) Carcinogenesis , vol.16 , pp. 2357-2362
    • Bastlova, T.1    Vodicka, P.2    Peterkova, K.3    Hemminki, K.4    Lambert, B.5
  • 29
    • 0029844440 scopus 로고    scopus 로고
    • Cytogenic studies of PCB77 on brown trout (Salmo trutta fario) using the micronucleaus test and the alkaline comet assay
    • Belpaeme,K., Delbeke,K., Zhu,L. and Kirsch-Volders,M. (1996a) Cytogenic studies of PCB77 on brown trout (Salmo trutta fario) using the micronucleaus test and the alkaline comet assay. Mutagenesis, 11, 485-492.
    • (1996) Mutagenesis , vol.11 , pp. 485-492
    • Belpaeme, K.1    Delbeke, K.2    Zhu, L.3    Kirsch-Volders, M.4
  • 30
    • 0030018828 scopus 로고    scopus 로고
    • PCBs do not induce DNA breakage in vitro in human lymphocytes
    • Belpaeme,K., Delbeke,K., Zhu,L. and Kirsch-Volders,M. (1996b) PCBs do not induce DNA breakage in vitro in human lymphocytes. Mutagenesis, 11, 383-389.
    • (1996) Mutagenesis , vol.11 , pp. 383-389
    • Belpaeme, K.1    Delbeke, K.2    Zhu, L.3    Kirsch-Volders, M.4
  • 31
    • 0029095190 scopus 로고
    • Assessment of DNA damage in leukocytes from infected and malnourished children by single cell gel electrophoresis/comet assay
    • Betancourt,M., Ortiz,R., Gonzalez,C., Perez,P., Cortes,L., Rodriguez,L. and Villasenor,L. (1995) Assessment of DNA damage in leukocytes from infected and malnourished children by single cell gel electrophoresis/comet assay. Mutat. Res., 331, 65-77.
    • (1995) Mutat. Res. , vol.331 , pp. 65-77
    • Betancourt, M.1    Ortiz, R.2    Gonzalez, C.3    Perez, P.4    Cortes, L.5    Rodriguez, L.6    Villasenor, L.7
  • 32
    • 0027521779 scopus 로고
    • Comparative studies on cytotoxic and genotoxic effects of two organic mercury compounds in lymphocytes and gastric mucosa cells of Sprague-Dawley rats
    • Betti,C., Barale,R. and Pool-Zobel,B.L. (1993) Comparative studies on cytotoxic and genotoxic effects of two organic mercury compounds in lymphocytes and gastric mucosa cells of Sprague-Dawley rats. Environ. Mol. Mutagen., 22, 172-180.
    • (1993) Environ. Mol. Mutagen. , vol.22 , pp. 172-180
    • Betti, C.1    Barale, R.2    Pool-Zobel, B.L.3
  • 33
    • 0028284199 scopus 로고
    • Microgel electrophoresis assay (comet test) and SCE analysis in human lumphocytes from 100 normal subjects
    • Betti,C., Davini,T., Giannessi,L., Loprieno,N. and Barale,R. (1994) Microgel electrophoresis assay (comet test) and SCE analysis in human lumphocytes from 100 normal subjects. Mutai. Res., 307, 323-333.
    • (1994) Mutai. Res. , vol.307 , pp. 323-333
    • Betti, C.1    Davini, T.2    Giannessi, L.3    Loprieno, N.4    Barale, R.5
  • 34
    • 0029069893 scopus 로고
    • Comparative studies by comet test and SCE analysis in human lymphocytes from 200 healthy subjects
    • Betti,C., Davini,T., Giannessi,L., Loprieno,N. and Barale,R. (1995) Comparative studies by comet test and SCE analysis in human lymphocytes from 200 healthy subjects. Mutat. Res., 343, 201-207.
    • (1995) Mutat. Res. , vol.343 , pp. 201-207
    • Betti, C.1    Davini, T.2    Giannessi, L.3    Loprieno, N.4    Barale, R.5
  • 35
    • 8944247269 scopus 로고    scopus 로고
    • Biomarker studies in northern Bohemia
    • Binkova,B. et al. (1996) Biomarker studies in northern Bohemia. Environ. Hlth Perpect., 3, 591-597.
    • (1996) Environ. Hlth Perpect. , vol.3 , pp. 591-597
    • Binkova, B.1
  • 37
    • 0030999459 scopus 로고    scopus 로고
    • Apoptosis and 1-methyl-2-nitroimidazole toxicity in CHO cells
    • Brezden,C.B., McClelland,R.A. and Rauth,A.M. (1997) Apoptosis and 1-methyl-2-nitroimidazole toxicity in CHO cells. Br. J. Cancer, 76, 180-188.
    • (1997) Br. J. Cancer , vol.76 , pp. 180-188
    • Brezden, C.B.1    McClelland, R.A.2    Rauth, A.M.3
  • 38
    • 0029837672 scopus 로고    scopus 로고
    • Determination of spatial patterns of DNA damage and repair in intestinal crypts by multi-cell gel electrophoresis
    • Brooks,R.A. and Winton,D.J. (1996) Determination of spatial patterns of DNA damage and repair in intestinal crypts by multi-cell gel electrophoresis. J. Cell. Sci., 109, 2061-2068.
    • (1996) J. Cell. Sci. , vol.109 , pp. 2061-2068
    • Brooks, R.A.1    Winton, D.J.2
  • 39
    • 1842290989 scopus 로고    scopus 로고
    • DNA excision repair profiles of normal and leukemic human lymphocytes: Functional analysis at the single cell level
    • Buschfort,C., Muller,M.R., Seeber,S., Rajewsky,M.F. and Thomale,J. (1997) DNA excision repair profiles of normal and leukemic human lymphocytes: functional analysis at the single cell level. Cancer Res., 57, 651-658.
    • (1997) Cancer Res. , vol.57 , pp. 651-658
    • Buschfort, C.1    Muller, M.R.2    Seeber, S.3    Rajewsky, M.F.4    Thomale, J.5
  • 40
    • 0029791978 scopus 로고    scopus 로고
    • The photomutagenicity of fluoroquinolones in tests for gene mutation, chromosomal aberration, gene conversion and DNA damage breakage (comet assay)
    • Chetelat,A.A., Albertini,S. and Gocke,E. (1996) The photomutagenicity of fluoroquinolones in tests for gene mutation, chromosomal aberration, gene conversion and DNA damage breakage (comet assay). Mutagenesis, 11, 497-504.
    • (1996) Mutagenesis , vol.11 , pp. 497-504
    • Chetelat, A.A.1    Albertini, S.2    Gocke, E.3
  • 41
    • 0029015296 scopus 로고
    • Rat mesothelial and tracheal epithelial cells show equal DNA sensitivity to hydrogen peroxide-induced oxidant injury
    • Churg,A., Keeling,B., Gilks,B., Porter,S. and Olive,P. (1995) Rat mesothelial and tracheal epithelial cells show equal DNA sensitivity to hydrogen peroxide-induced oxidant injury. Am. J. Physiol., 268, 832-838.
    • (1995) Am. J. Physiol. , vol.268 , pp. 832-838
    • Churg, A.1    Keeling, B.2    Gilks, B.3    Porter, S.4    Olive, P.5
  • 42
    • 0030995574 scopus 로고    scopus 로고
    • Genotoxicity of select herbicides in Rana catesbeiana tadpoles using the alkaline single-cell gel DNA electrophoresis (Comet) assay
    • Clemems,C., Ralph,S. and Petras,M. (1997) Genotoxicity of select herbicides in Rana catesbeiana tadpoles using the alkaline single-cell gel DNA electrophoresis (Comet) assay. Environ. Mol. Mutagen., 29, 277-288.
    • (1997) Environ. Mol. Mutagen. , vol.29 , pp. 277-288
    • Clemems, C.1    Ralph, S.2    Petras, M.3
  • 43
    • 0027375157 scopus 로고
    • Direct enzymatic detection of endogenous base damage in human lymphocyte DNA
    • Collins,A.R., Duthie,S.J. and Dobson,V.L. (1993) Direct enzymatic detection of endogenous base damage in human lymphocyte DNA. Carcinogenesis, 14, 1733-1735.
    • (1993) Carcinogenesis , vol.14 , pp. 1733-1735
    • Collins, A.R.1    Duthie, S.J.2    Dobson, V.L.3
  • 46
    • 0017883642 scopus 로고
    • Spectrofluorometric measurement of the binding of ethidium to superhelical DNA from cell nuclei
    • Cook,P.R. and Brazell,I.A. (1978) Spectrofluorometric measurement of the binding of ethidium to superhelical DNA from cell nuclei. Eur. J. Biochem., 84, 465-477.
    • (1978) Eur. J. Biochem. , vol.84 , pp. 465-477
    • Cook, P.R.1    Brazell, I.A.2
  • 47
    • 0018424479 scopus 로고
    • Describing the validity of carcinogen screening tests
    • Cooper,J.A., Saracci,R. and Cole,P. (1979) Describing the validity of carcinogen screening tests. Br. J. Cancer, 39, 87-89.
    • (1979) Br. J. Cancer , vol.39 , pp. 87-89
    • Cooper, J.A.1    Saracci, R.2    Cole, P.3
  • 48
    • 0011990849 scopus 로고
    • Evaluation of chemically induced DNA damage in germ cells of male mice using the single cell gel (SCG) electrophorectic assay
    • Croom,D.K., Andrews,P.W., Nascimbeni,B. and Tice,R.R. (1991) Evaluation of chemically induced DNA damage in germ cells of male mice using the single cell gel (SCG) electrophorectic assay. Environ. Mol. Mutagen., 17 (suppl. 19), 19.
    • (1991) Environ. Mol. Mutagen. , vol.17 , Issue.19 SUPPL. , pp. 19
    • Croom, D.K.1    Andrews, P.W.2    Nascimbeni, B.3    Tice, R.R.4
  • 49
    • 0344801362 scopus 로고    scopus 로고
    • Systemic genotoxic effect caused by ischemia-/reperfusion-/surgical trauma of the lower extremity - Detection of DNA chain breaks in leukocytes with the Comet assay
    • Dahouk,S., Plappert,U., Gerngross,H. and Willy,C. (1997) Systemic genotoxic effect caused by ischemia-/reperfusion-/surgical trauma of the lower extremity - detection of DNA chain breaks in leukocytes with the Comet assay. Langenbecks Arch. Chir. Suppl. Kongressbd, 114, 601-605.
    • (1997) Langenbecks Arch. Chir. Suppl. Kongressbd , vol.114 , pp. 601-605
    • Dahouk, S.1    Plappert, U.2    Gerngross, H.3    Willy, C.4
  • 50
    • 0030844682 scopus 로고    scopus 로고
    • Nereis virens (Annelida:Polychaeta) is not an adequate sentinel species to assess the genotoxic risk (Comet assay) of PAH exposure to the environment
    • De Boeck,M. and Kirsch-Volders,M. (1997) Nereis virens (Annelida:Polychaeta) is not an adequate sentinel species to assess the genotoxic risk (Comet assay) of PAH exposure to the environment. Environ. Mol. Mutagen. 30, 82-90.
    • (1997) Environ. Mol. Mutagen. , vol.30 , pp. 82-90
    • De Boeck, M.1    Kirsch-Volders, M.2
  • 51
    • 0029941438 scopus 로고    scopus 로고
    • The intracellular targets for nitric oxide toxicity to pancreatic beta-cells
    • Delaney,C.A. and Eizirik,D.L. (1996) The intracellular targets for nitric oxide toxicity to pancreatic beta-cells. Brazil. J. Med. Biol. Res., 29, 569-579.
    • (1996) Brazil. J. Med. Biol. Res. , vol.29 , pp. 569-579
    • Delaney, C.A.1    Eizirik, D.L.2
  • 52
    • 0027428461 scopus 로고
    • Endogenous nitric oxide induced by interleukin-1b in rat islets of Langerhans and HIT-T15 cells causes significant DNA damage as measured by the 'comet' assay
    • Delaney,C.A., Green,M.H.L., Lowe,J.E. and Green,I.C. (1993) Endogenous nitric oxide induced by interleukin-1b in rat islets of Langerhans and HIT-T15 cells causes significant DNA damage as measured by the 'comet' assay. FEBS Lett., 333, 291-295.
    • (1993) FEBS Lett. , vol.333 , pp. 291-295
    • Delaney, C.A.1    Green, M.H.L.2    Lowe, J.E.3    Green, I.C.4
  • 53
    • 0030915040 scopus 로고    scopus 로고
    • Use of the Comet assay to investigate possible interactions of nitric oxide and reactive oxygen species in the induction of DNA damage and inhibition of function in an insulin-secreting cell line
    • Delaney,C.A., Green,I.C., Lowe,J.E., Cunningham,J.M., Butler,A.R., Renton,L., D'Costa,I. and Green,M.H. (1997a) Use of the Comet assay to investigate possible interactions of nitric oxide and reactive oxygen species in the induction of DNA damage and inhibition of function in an insulin-secreting cell line. Mutat. Res., 375, 137-146.
    • (1997) Mutat. Res. , vol.375 , pp. 137-146
    • Delaney, C.A.1    Green, I.C.2    Lowe, J.E.3    Cunningham, J.M.4    Butler, A.R.5    Renton, L.6    D'Costa, I.7    Green, M.H.8
  • 54
    • 0030923812 scopus 로고    scopus 로고
    • Cytokines induce deoxyribonucleic acid strand breaks and apoptosis in human pancreatic islet cells
    • Delaney,C.A., Pavlovic,D., Hoorens,A., Pipeleers,D.G. and Eizirik,D.L. (1997b) Cytokines induce deoxyribonucleic acid strand breaks and apoptosis in human pancreatic islet cells. Endocrinology, 138, 2610-2614.
    • (1997) Endocrinology , vol.138 , pp. 2610-2614
    • Delaney, C.A.1    Pavlovic, D.2    Hoorens, A.3    Pipeleers, D.G.4    Eizirik, D.L.5
  • 55
    • 0025873546 scopus 로고
    • Genotoxic activity of potassium permanganate in acidic solution
    • De Méo,M., Laget,M., Castegnaro,M. and Dumenil,G. (1991) Genotoxic activity of potassium permanganate in acidic solution. Mutat. Res., 260, 295-306.
    • (1991) Mutat. Res. , vol.260 , pp. 295-306
    • De Méo, M.1    Laget, M.2    Castegnaro, M.3    Dumenil, G.4
  • 56
    • 0030791339 scopus 로고    scopus 로고
    • 2-Nitropropane-induced DNA damage in rat bone marrow
    • Deng,X.S., Tuo,J., Poulsen,H.E. and Loft,S. (1997) 2-Nitropropane-induced DNA damage in rat bone marrow. Mutat. Res., 391, 165-169.
    • (1997) Mutat. Res. , vol.391 , pp. 165-169
    • Deng, X.S.1    Tuo, J.2    Poulsen, H.E.3    Loft, S.4
  • 57
    • 0029952976 scopus 로고    scopus 로고
    • Detection of DNA damage after hyperbaric oxygen (HBO) therapy
    • Dennog,C., Hartmann,A., Frey,G. and Speit,G. (1996) Detection of DNA damage after hyperbaric oxygen (HBO) therapy. Mutagenesis, 11, 605-609.
    • (1996) Mutagenesis , vol.11 , pp. 605-609
    • Dennog, C.1    Hartmann, A.2    Frey, G.3    Speit, G.4
  • 58
    • 0028850387 scopus 로고
    • Wavelength dependence of laser-induced DNA damage in lymphocytes observed by single-cell electrophoresis
    • de With,A. and Greulich,K.O. (1995) Wavelength dependence of laser-induced DNA damage in lymphocytes observed by single-cell electrophoresis. J. Photochem. Photobiol B, 30, 71-76.
    • (1995) J. Photochem. Photobiol B , vol.30 , pp. 71-76
    • De With, A.1    Greulich, K.O.2
  • 59
    • 0028231896 scopus 로고
    • UV-B-laser induced DNA damage in lymphocytes observed by single-cell gel electrophoresis
    • de With,A., Leitz,G. and Greulich,K.O. (1994) UV-B-laser induced DNA damage in lymphocytes observed by single-cell gel electrophoresis. J. Photochem. Photobiol B, 1, 47-53.
    • (1994) J. Photochem. Photobiol B , vol.1 , pp. 47-53
    • De With, A.1    Leitz, G.2    Greulich, K.O.3
  • 60
    • 0030068610 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha and inerferongamma inhibit insulin secretion and cause DNA damage in unweaned-rat islets. Extent of nitric oxide involvement
    • Dunger,A., Cunningham,J.M., Delaney,C.A., Lowe,J.E., Green,M.H., Bone,A.J. and Green,I.C. (1996) Tumor necrosis factor-alpha and inerferongamma inhibit insulin secretion and cause DNA damage in unweaned-rat islets. Extent of nitric oxide involvement. Diabetes, 45, 183-189.
    • (1996) Diabetes , vol.45 , pp. 183-189
    • Dunger, A.1    Cunningham, J.M.2    Delaney, C.A.3    Lowe, J.E.4    Green, M.H.5    Bone, A.J.6    Green, I.C.7
  • 61
    • 0031028514 scopus 로고    scopus 로고
    • The influence of cell growth, detoxifying enzymes and DNA repair on hydrogen peroxide-mediated DNA damage (measured using the comet assay) in human cells
    • Duthie,S.J. and Collins,A.R. (1997) The influence of cell growth, detoxifying enzymes and DNA repair on hydrogen peroxide-mediated DNA damage (measured using the comet assay) in human cells. Free Radical Biol. Med., 22, 717-724.
    • (1997) Free Radical Biol. Med. , vol.22 , pp. 717-724
    • Duthie, S.J.1    Collins, A.R.2
  • 62
    • 0031410086 scopus 로고    scopus 로고
    • Uracil misincorporation in human DNA detected using single cell gel electrophoresis
    • Duthie,S.J. and McMillan,P. (1997) Uracil misincorporation in human DNA detected using single cell gel electrophoresis. Carcinogenesis, 18, 1709-1717.
    • (1997) Carcinogenesis , vol.18 , pp. 1709-1717
    • Duthie, S.J.1    McMillan, P.2
  • 63
    • 0029998738 scopus 로고    scopus 로고
    • Antioxidant supplementation decreases oxidative DNA damage in human lymphocytes
    • Duthie,S.J., Ma,A., Ross,M.A. and Collins,A.R. (1996) Antioxidant supplementation decreases oxidative DNA damage in human lymphocytes. Cancer. Res., 56, 1291-1295.
    • (1996) Cancer. Res. , vol.56 , pp. 1291-1295
    • Duthie, S.J.1    Ma, A.2    Ross, M.A.3    Collins, A.R.4
  • 64
    • 0030918017 scopus 로고    scopus 로고
    • The effect of dietary flavonoids on DNA damage (strand breaks and oxidised pyrimidines) and growth in human cells
    • Duthie,S.J., Johnson,W. and Dobson,V.L. (1997) The effect of dietary flavonoids on DNA damage (strand breaks and oxidised pyrimidines) and growth in human cells. Mutat. Res., 390, 141-151.
    • (1997) Mutat. Res. , vol.390 , pp. 141-151
    • Duthie, S.J.1    Johnson, W.2    Dobson, V.L.3
  • 66
    • 0030874743 scopus 로고    scopus 로고
    • Apoptosis in proliferative vitreoretinal disorders: Possible involvement of TGF-beta-induced RPE cell apoptosis
    • Esser,P., Heimann,K., Bartz-Schmidt,K., Fontana,A., Schraermeyer,U., Thumann, G. and Weller,M. (1997) Apoptosis in proliferative vitreoretinal disorders: possible involvement of TGF-beta-induced RPE cell apoptosis. Exp. Eye Res., 65, 365-378.
    • (1997) Exp. Eye Res. , vol.65 , pp. 365-378
    • Esser, P.1    Heimann, K.2    Bartz-Schmidt, K.3    Fontana, A.4    Schraermeyer, U.5    Thumann, G.6    Weller, M.7
  • 67
    • 0027170754 scopus 로고
    • DNA double-strand break repair deficiency in TK6 and other human B lymphoblast cell lines
    • Evans,H.H., Ricanati,M., Horng,M., Jiang,Q., Mencl,J. and Olive,P.L. (1993) DNA double-strand break repair deficiency in TK6 and other human B lymphoblast cell lines. Radiat. Res., 134, 307-315.
    • (1993) Radiat. Res. , vol.134 , pp. 307-315
    • Evans, H.H.1    Ricanati, M.2    Horng, M.3    Jiang, Q.4    Mencl, J.5    Olive, P.L.6
  • 69
    • 0028229425 scopus 로고
    • Alkali-labile sites are prevalent in kidney tissue DNA
    • Fairbairn,D.W., Reyes,W.A. and O'Neill,K.L. (1994) Alkali-labile sites are prevalent in kidney tissue DNA. Cancer Lett., 81, 67-76.
    • (1994) Cancer Lett. , vol.81 , pp. 67-76
    • Fairbairn, D.W.1    Reyes, W.A.2    O'Neill, K.L.3
  • 71
    • 0029864861 scopus 로고    scopus 로고
    • Analysis of DNA alkylation damage and repair in mammalian cells by the comet assay
    • Fortini,P., Raspaglio,G., Falchi,M. and Dogliotti,E. (1996) Analysis of DNA alkylation damage and repair in mammalian cells by the comet assay. Mutagenesis, 11, 169-175.
    • (1996) Mutagenesis , vol.11 , pp. 169-175
    • Fortini, P.1    Raspaglio, G.2    Falchi, M.3    Dogliotti, E.4
  • 73
    • 0011922729 scopus 로고
    • Evaluation of chemically-induced DNA damage in germinal tissue of female mice using the single cell gel (SCG) assay
    • Friend,J.H., Carpenter,T.D. and Tice,R.R. (1993) Evaluation of chemically-induced DNA damage in germinal tissue of female mice using the single cell gel (SCG) assay. Environ, Mol. Mutagen., 21 (suppl. 22), 20.
    • (1993) Environ, Mol. Mutagen. , vol.21 , Issue.22 SUPPL. , pp. 20
    • Friend, J.H.1    Carpenter, T.D.2    Tice, R.R.3
  • 74
    • 0026738581 scopus 로고
    • Single-cell electrophoresis applied to the analysis of UV-C damage and its repair in human cells
    • Gedik,C.M., Ewen,S.W.B. and Collins,A.R. (1992) Single-cell electrophoresis applied to the analysis of UV-C damage and its repair in human cells. Int. J. Radiat. Biol., 62, 313-320.
    • (1992) Int. J. Radiat. Biol. , vol.62 , pp. 313-320
    • Gedik, C.M.1    Ewen, S.W.B.2    Collins, A.R.3
  • 75
    • 0029958580 scopus 로고    scopus 로고
    • E-2-Hexenal-induced DNA damage and formation of cyclic 1,N2-(1,3-propano)-2′-deoxyguanosine adducts in mammalian cells
    • Golzer,P., Janzowski,C., Pool-Zobel,B.L. and Eisenbrand,G. (1996) (E)-2-Hexenal-induced DNA damage and formation of cyclic 1,N2-(1,3-propano)-2′-deoxyguanosine adducts in mammalian cells. Chem. Res. Toxicol., 9, 1207-1213.
    • (1996) Chem. Res. Toxicol. , vol.9 , pp. 1207-1213
    • Golzer, P.1    Janzowski, C.2    Pool-Zobel, B.L.3    Eisenbrand, G.4
  • 76
    • 0028907941 scopus 로고
    • Comet assay to measure DNA damage in apoptotic cells
    • Gopalakrishna,P. and Khar,A. (1995) Comet assay to measure DNA damage in apoptotic cells. J. Biochem. Biophys. Methods, 30, 69-73.
    • (1995) J. Biochem. Biophys. Methods , vol.30 , pp. 69-73
    • Gopalakrishna, P.1    Khar, A.2
  • 77
    • 0028203701 scopus 로고
    • Effects of cytokines and nitric oxide donors on insulin secretion, cyclic GMP and DNA damage; relation to nitric oxide production
    • Green,I.C., Cunningham,J.M., Delaney,C.A., Elphick,M.R., Mabley,J.G. and Green,M.H.L. (1994) Effects of cytokines and nitric oxide donors on insulin secretion, cyclic GMP and DNA damage; relation to nitric oxide production. Biochem. Soc. Trans., 22, 30-37.
    • (1994) Biochem. Soc. Trans. , vol.22 , pp. 30-37
    • Green, I.C.1    Cunningham, J.M.2    Delaney, C.A.3    Elphick, M.R.4    Mabley, J.G.5    Green, M.H.L.6
  • 78
    • 0026501421 scopus 로고
    • UV-C sensitivity of unstimulated and stimulated human lymphocytes from normal and xeroderma pigmentosum donors in the comet assay: A potential diagnostic technique
    • Green,M.H., Lowe,J.E., Harcourt,S.A., Akinluyi,P., Rowe,T., Cole,J., Anstey,A.V. and Arlett,C.F. (1992) UV-C sensitivity of unstimulated and stimulated human lymphocytes from normal and xeroderma pigmentosum donors in the comet assay: a potential diagnostic technique. Mutat. Res., 273, 137-144.
    • (1992) Mutat. Res. , vol.273 , pp. 137-144
    • Green, M.H.1    Lowe, J.E.2    Harcourt, S.A.3    Akinluyi, P.4    Rowe, T.5    Cole, J.6    Anstey, A.V.7    Arlett, C.F.8
  • 79
    • 0028147174 scopus 로고
    • Effect of diet and vitamin C on DNA strand breakage in freshlyisolated human white blood cells
    • Green,M.H., Lowe,J.E., Waugh,A.P., Aldridge,K.E., Cole,J. and Arlett,C.F. (1994) Effect of diet and vitamin C on DNA strand breakage in freshlyisolated human white blood cells. Mutat. Res., 316, 91-102.
    • (1994) Mutat. Res. , vol.316 , pp. 91-102
    • Green, M.H.1    Lowe, J.E.2    Waugh, A.P.3    Aldridge, K.E.4    Cole, J.5    Arlett, C.F.6
  • 80
    • 0029814868 scopus 로고    scopus 로고
    • Comet assay to detect nitric oxide-dependent DNA damage in mammalian cells
    • Green,M.H., Lowe,J.E., Delaney,C.A. and Green,I.C. (1996) Comet assay to detect nitric oxide-dependent DNA damage in mammalian cells. Methods Enzymol., 269, 243-266.
    • (1996) Methods Enzymol. , vol.269 , pp. 243-266
    • Green, M.H.1    Lowe, J.E.2    Delaney, C.A.3    Green, I.C.4
  • 81
    • 0027787965 scopus 로고
    • Differential DNA damage detected in hybridomas
    • Grigsby,R.V., Fairbairn,D. and O'Neill,K.L. (1993) Differential DNA damage detected in hybridomas. Hybridoma, 12, 755-761.
    • (1993) Hybridoma , vol.12 , pp. 755-761
    • Grigsby, R.V.1    Fairbairn, D.2    O'Neill, K.L.3
  • 82
    • 0031409982 scopus 로고    scopus 로고
    • Influence of diets containing high and low risk factors for colon cancer on early stages of carcinogenesis in human flora-associated (HFA) rats
    • Hambly,R.J., Rumney,C.J., Cunninghame,M., Fletcher,J.M., Rijken,P.J. and Rowland,I.R. (1997) Influence of diets containing high and low risk factors for colon cancer on early stages of carcinogenesis in human flora-associated (HFA) rats. Carcinogenesis, 18, 1525-1539.
    • (1997) Carcinogenesis , vol.18 , pp. 1525-1539
    • Hambly, R.J.1    Rumney, C.J.2    Cunninghame, M.3    Fletcher, J.M.4    Rijken, P.J.5    Rowland, I.R.6
  • 83
    • 0030980846 scopus 로고    scopus 로고
    • A comparative investigation of DNA adducts, DNA strand breaks and gene mutations induced by benzo[a]pyrene and (±)-anti-benzo[a]pyrene-7,8-diol 9,10-oxide in cultured human cells
    • Hanelt,S., Helbig,R., Hartmann,A., Lang,M., Seidel,A. and Speit,G. (1997) A comparative investigation of DNA adducts, DNA strand breaks and gene mutations induced by benzo[a]pyrene and (±)-anti-benzo[a]pyrene-7,8-diol 9,10-oxide in cultured human cells. Mutat. Res., 390, 179-188.
    • (1997) Mutat. Res. , vol.390 , pp. 179-188
    • Hanelt, S.1    Helbig, R.2    Hartmann, A.3    Lang, M.4    Seidel, A.5    Speit, G.6
  • 84
    • 0028364510 scopus 로고
    • Comparative investigations of the genotoxic effects of metals in the single cell (SCG) assay and the sister chromatid exchange (SCE) test
    • Hartmann,A. and Speit,G. (1994) Comparative investigations of the genotoxic effects of metals in the single cell (SCG) assay and the sister chromatid exchange (SCE) test. Environ. Mol. Mutagen., 23, 299-305.
    • (1994) Environ. Mol. Mutagen. , vol.23 , pp. 299-305
    • Hartmann, A.1    Speit, G.2
  • 85
    • 0029915960 scopus 로고    scopus 로고
    • Effect of arsenic and cadmium on the persistence of mutagen-induced DNA lesions in human cells
    • Hartmann,A. and Speit,G. (1996) Effect of arsenic and cadmium on the persistence of mutagen-induced DNA lesions in human cells. Environ. Mol. Mutagen., 27, 98-104.
    • (1996) Environ. Mol. Mutagen. , vol.27 , pp. 98-104
    • Hartmann, A.1    Speit, G.2
  • 86
    • 0031557136 scopus 로고    scopus 로고
    • The contribution of cytotoxicity to DNA-effects in the single cell gel test (comet assay)
    • Hartmann.A. and Speit,G. (1997) The contribution of cytotoxicity to DNA-effects in the single cell gel test (comet assay). Toxicol. Lett., 90, 183-188.
    • (1997) Toxicol. Lett. , vol.90 , pp. 183-188
    • Hartmann, A.1    Speit, G.2
  • 88
    • 0028988762 scopus 로고
    • DNA-damaging effect of cyclophosphamide on human blood cells in vivo and in vitro studied with the single cell gel test (comet assay)
    • Hartmann,A., Herkommer,K., Gluck,M. and Speit,G. (1995a) DNA-damaging effect of cyclophosphamide on human blood cells in vivo and in vitro studied with the single cell gel test (comet assay). Environ. Mol. Mutagen., 25, 180-187.
    • (1995) Environ. Mol. Mutagen. , vol.25 , pp. 180-187
    • Hartmann, A.1    Herkommer, K.2    Gluck, M.3    Speit, G.4
  • 90
    • 0030022191 scopus 로고    scopus 로고
    • DNA damage following combination of radiation with the bioreductive drug AQ4N: Possible selective toxicity to oxic and hypoxic tumor cells
    • Hejmadi,M.V., McKeown,S.R., Friery,O.P., McIntyre,I.A., Patterson,L.H. and Hirst,D.G. (1996) DNA damage following combination of radiation with the bioreductive drug AQ4N: possible selective toxicity to oxic and hypoxic tumor cells. Br. J. Cancer, 73, 499-505.
    • (1996) Br. J. Cancer , vol.73 , pp. 499-505
    • Hejmadi, M.V.1    McKeown, S.R.2    Friery, O.P.3    McIntyre, I.A.4    Patterson, L.H.5    Hirst, D.G.6
  • 91
    • 0030858828 scopus 로고    scopus 로고
    • DNA effects in repair-deficient V79 Chinese hamster cells studied with the Comet assay
    • Helbig,R. and Speit,G. (1997) DNA effects in repair-deficient V79 Chinese hamster cells studied with the Comet assay. Mutat. Res., 377, 279-286.
    • (1997) Mutat. Res. , vol.377 , pp. 279-286
    • Helbig, R.1    Speit, G.2
  • 92
    • 0031015884 scopus 로고    scopus 로고
    • Alkaline single cell electrophoresis of DNA fragments in biomonitoring for genotoxicity: An introductory study on healthy human volunteers
    • Hellman,B., Vaghef,H., Friis,L. and Edling,C. (1997) Alkaline single cell electrophoresis of DNA fragments in biomonitoring for genotoxicity: an introductory study on healthy human volunteers. Int. Arch. Occup. Environ. Hlth, 69, 185-192.
    • (1997) Int. Arch. Occup. Environ. Hlth , vol.69 , pp. 185-192
    • Hellman, B.1    Vaghef, H.2    Friis, L.3    Edling, C.4
  • 93
    • 0031973021 scopus 로고    scopus 로고
    • The ability of the comet assay to discriminate between genotoxins and cytotoxins
    • Henderson,L., Wolfreys,A., Fedyk,J., Bourner,C. and Windebank,S. (1998) The ability of the comet assay to discriminate between genotoxins and cytotoxins. Mutagenesis, 13, 89-94.
    • (1998) Mutagenesis , vol.13 , pp. 89-94
    • Henderson, L.1    Wolfreys, A.2    Fedyk, J.3    Bourner, C.4    Windebank, S.5
  • 94
    • 0028138769 scopus 로고
    • Vulnerability to oxygen radicals is more important than impaired repair in hepatocytic deoxyribonucleic acid damage in aging
    • Higami,Y., Shimokawa,I., Okimoto,T. and Ikeda,T. (1994a) Vulnerability to oxygen radicals is more important than impaired repair in hepatocytic deoxyribonucleic acid damage in aging. Lab. Invest., 71, 650-656.
    • (1994) Lab. Invest. , vol.71 , pp. 650-656
    • Higami, Y.1    Shimokawa, I.2    Okimoto, T.3    Ikeda, T.4
  • 95
    • 0028029279 scopus 로고
    • An age-related increase in the basal level of DNA damage and DNA vulnerability to oxygen radicals in the individual hepatocytes of male F344 rats
    • Higami,Y., Shimokawa,I., Okimoto,T. and Ikeda,T. (1994b) An age-related increase in the basal level of DNA damage and DNA vulnerability to oxygen radicals in the individual hepatocytes of male F344 rats. Mutat. Res., 316, 59-67.
    • (1994) Mutat. Res. , vol.316 , pp. 59-67
    • Higami, Y.1    Shimokawa, I.2    Okimoto, T.3    Ikeda, T.4
  • 96
    • 0342657060 scopus 로고
    • DNA damage evaluation using the rodent in vitro hepatocyte culture system and the single cell (SCG) electrophoretic assay
    • Hirai,O., Andrews,P.W., Tice,R.R. and Naumann,C.H. (1991) DNA damage evaluation using the rodent in vitro hepatocyte culture system and the single cell (SCG) electrophoretic assay. Environ. Mol. Mutagen., 17 (suppl. 19), 31.
    • (1991) Environ. Mol. Mutagen. , vol.17 , Issue.19 SUPPL. , pp. 31
    • Hirai, O.1    Andrews, P.W.2    Tice, R.R.3    Naumann, C.H.4
  • 97
    • 0029819981 scopus 로고    scopus 로고
    • Radiosensitivity, apoptosis and repair of DNA double-strand breaks in radiation-sensitive Chinese hamster ovary cell mutants treated at different dose rates
    • Hu,Q. and Hill,R.P. (1996) Radiosensitivity, apoptosis and repair of DNA double-strand breaks in radiation-sensitive Chinese hamster ovary cell mutants treated at different dose rates. Radiat. Res., 146, 636-645.
    • (1996) Radiat. Res. , vol.146 , pp. 636-645
    • Hu, Q.1    Hill, R.P.2
  • 98
    • 0028821921 scopus 로고
    • Detection of hypoxic fractions in murine tumours by comet assay: Comparison with other techniques
    • Hu,Q., Kavanagh,M.C., Newcombe,D. and Hill,R.P. (1995) Detection of hypoxic fractions in murine tumours by comet assay: comparison with other techniques. Radiat. Res., 144, 266-275.
    • (1995) Radiat. Res. , vol.144 , pp. 266-275
    • Hu, Q.1    Kavanagh, M.C.2    Newcombe, D.3    Hill, R.P.4
  • 99
    • 0030936364 scopus 로고    scopus 로고
    • Reproducibility of human sperm DNA measurements using the alkaline single cell gel electrophoresis assay
    • Hughes,C.M., Lewis,S.E., McKelvey-Manin,V.J. and Thompson,W. (1997) Reproducibility of human sperm DNA measurements using the alkaline single cell gel electrophoresis assay. Mutat. Res., 374, 261-268.
    • (1997) Mutat. Res. , vol.374 , pp. 261-268
    • Hughes, C.M.1    Lewis, S.E.2    McKelvey-Manin, V.J.3    Thompson, W.4
  • 100
    • 0030758934 scopus 로고    scopus 로고
    • Elevated frequency of p53. independent apoptosis after irradiation increases levels of DNA breaks in ataxia telangiectasia lymphoblasts
    • Humar,B., Muller,H. and Scott,R.J. (1997) Elevated frequency of p53. independent apoptosis after irradiation increases levels of DNA breaks in ataxia telangiectasia lymphoblasts. Int. J. Radiat. Biol., 72, 257-269.
    • (1997) Int. J. Radiat. Biol. , vol.72 , pp. 257-269
    • Humar, B.1    Muller, H.2    Scott, R.J.3
  • 101
    • 0027243442 scopus 로고
    • Single-ceil gel technique supports hit probability calculations
    • Jostes,R.F., Hui,T.E. and Cross,F.T. (1993) Single-ceil gel technique supports hit probability calculations. Hlth Phys., 64, 675-679.
    • (1993) Hlth Phys. , vol.64 , pp. 675-679
    • Jostes, R.F.1    Hui, T.E.2    Cross, F.T.3
  • 102
    • 0029554145 scopus 로고
    • Cytotoxicity of antitumour agents toward cultured murine leukemia L1210 cells under a serum-deprived apoptotic condition
    • Kasamatsu,T., Kohda,K. and Kawazoe,Y. (1995) Cytotoxicity of antitumour agents toward cultured murine leukemia L1210 cells under a serum-deprived apoptotic condition. Anticancer Res., 15, 2597-2600.
    • (1995) Anticancer Res. , vol.15 , pp. 2597-2600
    • Kasamatsu, T.1    Kohda, K.2    Kawazoe, Y.3
  • 103
    • 0030002162 scopus 로고    scopus 로고
    • Comparison of chemically induced DNA breakage in cellular and subcellular systems using the comet assay
    • Kasamatsu,T., Kohda,K. and Kawazoe,Y. (1996) Comparison of chemically induced DNA breakage in cellular and subcellular systems using the comet assay. Mutat. Res., 369, 1-6.
    • (1996) Mutat. Res. , vol.369 , pp. 1-6
    • Kasamatsu, T.1    Kohda, K.2    Kawazoe, Y.3
  • 105
    • 0029045164 scopus 로고
    • The comet moment as a measure of DNA damage in the comet assay
    • Kent,C.R., Eady,J.J., Ross,G.M. and Steel,G.G. (1995) The comet moment as a measure of DNA damage in the comet assay. Int. J. Radiat. Biol., 67, 655-660.
    • (1995) Int. J. Radiat. Biol. , vol.67 , pp. 655-660
    • Kent, C.R.1    Eady, J.J.2    Ross, G.M.3    Steel, G.G.4
  • 106
    • 0030580947 scopus 로고    scopus 로고
    • The comet assay: Mechanisms and technical considerations
    • Klaude,M., Eriksson,S., Nygren,J. and Ahnstrom,G. (1996) The comet assay: mechanisms and technical considerations. Mutat. Res., 363, 89-96.
    • (1996) Mutat. Res. , vol.363 , pp. 89-96
    • Klaude, M.1    Eriksson, S.2    Nygren, J.3    Ahnstrom, G.4
  • 107
    • 0027284021 scopus 로고
    • DNA single-strand breaks in human lens epithelial cells from patients with cataract
    • Kleiman,N.J. and Spector,A. (1993) DNA single-strand breaks in human lens epithelial cells from patients with cataract. Curr. Eye Res., 12, 423-431.
    • (1993) Curr. Eye Res. , vol.12 , pp. 423-431
    • Kleiman, N.J.1    Spector, A.2
  • 108
    • 0030740027 scopus 로고    scopus 로고
    • Propylene oxide and epichlorohydrin induced DNA strand breaks in human diploid fibroblasts
    • Kolman,A., Spivak,I., Naslund,M., Dusinska,M. and Cedervall,B. (1997) Propylene oxide and epichlorohydrin induced DNA strand breaks in human diploid fibroblasts. Environ. Mol. Mutagen., 30, 40-46.
    • (1997) Environ. Mol. Mutagen. , vol.30 , pp. 40-46
    • Kolman, A.1    Spivak, I.2    Naslund, M.3    Dusinska, M.4    Cedervall, B.5
  • 109
    • 0030575556 scopus 로고    scopus 로고
    • The alkaline Comet test on plant cells: A new genotoxicity test for DNA strand breaks in Vicia faba root cells
    • Koppen,G. and Verschaeve,L. (1996) The alkaline Comet test on plant cells: a new genotoxicity test for DNA strand breaks in Vicia faba root cells. Mutat. Res., 360, 193-200.
    • (1996) Mutat. Res. , vol.360 , pp. 193-200
    • Koppen, G.1    Verschaeve, L.2
  • 110
    • 0030044568 scopus 로고    scopus 로고
    • Assessment of DNA damage in canine peripheral blood and bone marrow after total body irradiation using the single-cell gel electrophoresis technique
    • Kreja,L., Selig,C. and Nothdurft,W. (1996a) Assessment of DNA damage in canine peripheral blood and bone marrow after total body irradiation using the single-cell gel electrophoresis technique. Mutat. Res., 359, 63-70.
    • (1996) Mutat. Res. , vol.359 , pp. 63-70
    • Kreja, L.1    Selig, C.2    Nothdurft, W.3
  • 111
    • 0029897781 scopus 로고    scopus 로고
    • Radiation-induced DNA damage in canine hemopoietic cells and stromal cells as measured by the comet assay
    • Kreja,L., Selig,C., Plappert,U. and Nothdurft,W. (1996b) Radiation-induced DNA damage in canine hemopoietic cells and stromal cells as measured by the comet assay. Environ. Mol. Mutagen., 27, 39-45.
    • (1996) Environ. Mol. Mutagen. , vol.27 , pp. 39-45
    • Kreja, L.1    Selig, C.2    Plappert, U.3    Nothdurft, W.4
  • 112
    • 0028136856 scopus 로고
    • DNA strand breakage, cytotoxicity and mutagenicity of hydrogen peroxide treatment at 4°C and 37°C in L5178Y sublines
    • Kruszewski,M., Green,M.H., Lowe,J.E. and Szumiel,I. (1994) DNA strand breakage, cytotoxicity and mutagenicity of hydrogen peroxide treatment at 4°C and 37°C in L5178Y sublines. Mutat. Res., 308, 233-241.
    • (1994) Mutat. Res. , vol.308 , pp. 233-241
    • Kruszewski, M.1    Green, M.H.2    Lowe, J.E.3    Szumiel, I.4
  • 113
    • 0031015126 scopus 로고    scopus 로고
    • Repair of gamma-irradiation induced DNA single-strand breaks in human bone marrow cells: Effects of a second irradiation
    • Lankinen,M.H. and Vilpo,J.A. (1997) Repair of gamma-irradiation induced DNA single-strand breaks in human bone marrow cells: effects of a second irradiation. Mutat. Res., 373, 31-37.
    • (1997) Mutat. Res. , vol.373 , pp. 31-37
    • Lankinen, M.H.1    Vilpo, J.A.2
  • 114
    • 0029954286 scopus 로고    scopus 로고
    • UV- and gamma-irradiation-induced DNA single-strand breaks and their repair in human blood granulocytes and lymphocytes
    • Lankinen,M.H., Vilpo,L.M. and Vilpo,J.A. (1996) UV-and gamma-irradiation-induced DNA single-strand breaks and their repair in human blood granulocytes and lymphocytes. Mutat. Res., 352, 31-38.
    • (1996) Mutat. Res. , vol.352 , pp. 31-38
    • Lankinen, M.H.1    Vilpo, L.M.2    Vilpo, J.A.3
  • 115
    • 0031009605 scopus 로고    scopus 로고
    • Assessment of DNA damage induced in vitro by etoposide and two fungicides (carbendazim and chlorothalonil) in human lymphocytes with the Comet assay
    • Lebailly,P., Vigreux,C., Godard,T., Sichel,F., Bar,E., LeTalaer,J.Y., Henry-Amar,M. and Gauduchon,P. (1997) Assessment of DNA damage induced in vitro by etoposide and two fungicides (carbendazim and chlorothalonil) in human lymphocytes with the Comet assay. Mutat. Res., 375, 205-217.
    • (1997) Mutat. Res. , vol.375 , pp. 205-217
    • Lebailly, P.1    Vigreux, C.2    Godard, T.3    Sichel, F.4    Bar, E.5    LeTalaer, J.Y.6    Henry-Amar, M.7    Gauduchon, P.8
  • 116
    • 0029557172 scopus 로고
    • The determination of radiation-induced damage in lymphocytes using the micronucleus and microgel electrophoresis 'Comet' assays
    • Malcolmson,A.M., Davies,G., Hanson,J.A., Deeley,J.O., Gaffney,C.C., McGregor,A.D. and Kerby,I.J. (1995) The determination of radiation-induced damage in lymphocytes using the micronucleus and microgel electrophoresis 'Comet' assays. Eur. J. Cancer, 31A, 2320-2323.
    • (1995) Eur. J. Cancer , vol.31 A , pp. 2320-2323
    • Malcolmson, A.M.1    Davies, G.2    Hanson, J.A.3    Deeley, J.O.4    Gaffney, C.C.5    McGregor, A.D.6    Kerby, I.J.7
  • 117
    • 0030868723 scopus 로고    scopus 로고
    • A neurotoxin N-methyl(R)salsolinol induces apoptotic cell death in differentiated human dopaminergic neuroblastoma SH-SY5Y cells
    • Maruyama,W., Benedetti,M.S., Takahashi,T. and Naoi,M. (1997a) A neurotoxin N-methyl(R)salsolinol induces apoptotic cell death in differentiated human dopaminergic neuroblastoma SH-SY5Y cells. Neurosci. Lett., 232, 147-150.
    • (1997) Neurosci. Lett. , vol.232 , pp. 147-150
    • Maruyama, W.1    Benedetti, M.S.2    Takahashi, T.3    Naoi, M.4
  • 118
    • 0030957199 scopus 로고    scopus 로고
    • An endogenous dopaminergic neurotoxin, N-methyl-(R)-salsolinol, induces DNA damage in human dopaminergic neuroblastoma SH-SY5Y cells
    • Maruyama,W., Naoi,M., Kasamatsu,T., Hashizume,Y., Takahashi,T., Kohda,K. and Dostert,P. (1997b) An endogenous dopaminergic neurotoxin, N-methyl-(R)-salsolinol, induces DNA damage in human dopaminergic neuroblastoma SH-SY5Y cells. J. Neurochem., 69, 322-329.
    • (1997) J. Neurochem. , vol.69 , pp. 322-329
    • Maruyama, W.1    Naoi, M.2    Kasamatsu, T.3    Hashizume, Y.4    Takahashi, T.5    Kohda, K.6    Dostert, P.7
  • 119
    • 0030758092 scopus 로고    scopus 로고
    • Evaluation of manual and image analysis quantification of DNA damage in the alkaline Comet assay
    • McCarthy,P.J., Sweetman,S.F., McKenna,P.G. and McKelvey-Martin,V.J. (1997) Evaluation of manual and image analysis quantification of DNA damage in the alkaline Comet assay. Mutagenesis, 12, 209-214.
    • (1997) Mutagenesis , vol.12 , pp. 209-214
    • McCarthy, P.J.1    Sweetman, S.F.2    McKenna, P.G.3    McKelvey-Martin, V.J.4
  • 120
    • 0031021258 scopus 로고    scopus 로고
    • Delayed repair of DNA damage by ionising radiation in cells from patients with juvenile systemic lupus erythomatosus and rheumatoid arthritis
    • McCurdy,D., Tai,L.Q., Fias,S. and Wang,Z. (1997) Delayed repair of DNA damage by ionising radiation in cells from patients with juvenile systemic lupus erythomatosus and rheumatoid arthritis. Radiat. Res., 147, 48-54.
    • (1997) Radiat. Res. , vol.147 , pp. 48-54
    • McCurdy, D.1    Tai, L.Q.2    Fias, S.3    Wang, Z.4
  • 121
    • 0011835987 scopus 로고
    • Analysis of DNA content and integrity in cells extracted from bladder washing and voided urine specimens, in bladder cancer patients, using the comet assay
    • McKelvey-Martin,V.J., Butler,M. and Stewan,L.H. (1992) Analysis of DNA content and integrity in cells extracted from bladder washing and voided urine specimens, in bladder cancer patients, using the comet assay. Mutat. Res., 271, 163.
    • (1992) Mutat. Res. , vol.271 , pp. 163
    • McKelvey-Martin, V.J.1    Butler, M.2    Stewan, L.H.3
  • 123
    • 0030925921 scopus 로고    scopus 로고
    • Two potential clinical applications of alkaline single-cell electrophoresis assay: (1) human bladder washings and transitional cell carcinoma of the bladder; (2) human sperm and male infertility
    • McKelvey-Martin,V.J., Melia,N., Walsh,I.K., Johnston,S.R., Hughes,C.M., Lewis,S.E. and Thompson,W. (1997) Two potential clinical applications of alkaline single-cell electrophoresis assay: (1) human bladder washings and transitional cell carcinoma of the bladder; (2) human sperm and male infertility. Mutat. Res., 375, 93-104.
    • (1997) Mutat. Res. , vol.375 , pp. 93-104
    • McKelvey-Martin, V.J.1    Melia, N.2    Walsh, I.K.3    Johnston, S.R.4    Hughes, C.M.5    Lewis, S.E.6    Thompson, W.7
  • 124
    • 0031006223 scopus 로고    scopus 로고
    • A Comet assay of DNA damage and repair in K562 cells after photodynamic theraphy using haematoporphyrin derivative, methylene blue and mesotetrahydroxyphenylchlorin
    • McNair,F.I., Marples,B., West,C.M. and Moore, J.V. (1997) A Comet assay of DNA damage and repair in K562 cells after photodynamic theraphy using haematoporphyrin derivative, methylene blue and mesotetrahydroxyphenylchlorin. Br. J. Cancer, 75, 1721-1729.
    • (1997) Br. J. Cancer , vol.75 , pp. 1721-1729
    • McNair, F.I.1    Marples, B.2    West, C.M.3    Moore, J.V.4
  • 125
    • 0027347186 scopus 로고
    • 2 induced DNA single strand breaks using the single cell gel assay
    • 2 induced DNA single strand breaks using the single cell gel assay. Cytobios, 74, 144-153.
    • (1993) Cytobios , vol.74 , pp. 144-153
    • Meyers, C.D.1    Fairbairn, D.W.2    O'Neill, K.L.3
  • 126
    • 0030039174 scopus 로고    scopus 로고
    • The role of cavitation in the induction of cellular DNA damage by ultrasound and lithotripter shock waves in vitro
    • Miller,D.L. and Thomas,R.M. (1996) The role of cavitation in the induction of cellular DNA damage by ultrasound and lithotripter shock waves in vitro. Ultrasound. Med. Biol., 22, 681-687.
    • (1996) Ultrasound. Med. Biol. , vol.22 , pp. 681-687
    • Miller, D.L.1    Thomas, R.M.2
  • 127
    • 0029101757 scopus 로고
    • Comet assay reveals DNA strand breaks induced by ultrasonic cavitation in vitro
    • Miller,D.L., Thomas,R.M. and Buschbom,R.L. (1995) Comet assay reveals DNA strand breaks induced by ultrasonic cavitation in vitro. Ultrasound. Med. Biol., 21, 841-848.
    • (1995) Ultrasound. Med. Biol. , vol.21 , pp. 841-848
    • Miller, D.L.1    Thomas, R.M.2    Buschbom, R.L.3
  • 128
    • 0029993169 scopus 로고    scopus 로고
    • The role of ultraviolet light in the induction of cellular DNA damage by a spark-gap lithotripter in vitro
    • Miller,D.L., Thomas,R.M. and Thrall,B.D. (1996) The role of ultraviolet light in the induction of cellular DNA damage by a spark-gap lithotripter in vitro. J. Urol., 156, 286-290.
    • (1996) J. Urol. , vol.156 , pp. 286-290
    • Miller, D.L.1    Thomas, R.M.2    Thrall, B.D.3
  • 130
    • 0030596126 scopus 로고    scopus 로고
    • Genotoxicity of the laxative drug components emodin, aloe-emodin and danthron in mammalian cells: Topoisomerase II mediated? Mutat
    • Muller,S.O., Eckert,I., Lutz,W.K. and Stopper,H. (1996) Genotoxicity of the laxative drug components emodin, aloe-emodin and danthron in mammalian cells: topoisomerase II mediated? Mutat. Res., 371, 165-173.
    • (1996) Res. , vol.371 , pp. 165-173
    • Muller, S.O.1    Eckert, I.2    Lutz, W.K.3    Stopper, H.4
  • 131
    • 0028295112 scopus 로고
    • Comet assay studies of radiation-induced DNA damage and repair in various tumour cell lines
    • Muller,W.U., Bauch,T., Streffer,C., Niedereichholz,F. and Bocker,W. (1994) Comet assay studies of radiation-induced DNA damage and repair in various tumour cell lines. Int. J. Radiat. Biol., 65, 315-319.
    • (1994) Int. J. Radiat. Biol. , vol.65 , pp. 315-319
    • Muller, W.U.1    Bauch, T.2    Streffer, C.3    Niedereichholz, F.4    Bocker, W.5
  • 132
    • 0343542276 scopus 로고
    • Evaluation of DNA damage in golden mice (Ochrotomys nutalli) inhabiting a hazardous waste site
    • Nascimbeni,B., Phillips,M.D., Croom,D.K., Andrews,P.W. and Tice,R.R. (1991) Evaluation of DNA damage in golden mice (Ochrotomys nutalli) inhabiting a hazardous waste site. Environ. Mol. Mutagen., 17 (suppl. 19), 55.
    • (1991) Environ. Mol. Mutagen. , vol.17 , Issue.19 SUPPL. , pp. 55
    • Nascimbeni, B.1    Phillips, M.D.2    Croom, D.K.3    Andrews, P.W.4    Tice, R.R.5
  • 133
    • 0030997488 scopus 로고    scopus 로고
    • A fast comet assay variant for solid tissue cells. The assessment of DNA damage in higher plants
    • Navarrete,M.H., Carrera,P., de-Miguel,M. and de la Torre,C. (1997) A fast comet assay variant for solid tissue cells. The assessment of DNA damage in higher plants. Mutat. Res., 389, 271-277.
    • (1997) Mutat. Res. , vol.389 , pp. 271-277
    • Navarrete, M.H.1    Carrera, P.2    De-Miguel, M.3    De La Torre, C.4
  • 134
    • 0028826450 scopus 로고
    • Comet assay analysis of repair of DNA strand breaks in normal and deficient human cells exposed to radiations and chemicals. Evidence for a repair pathway specificity of DNA ligation
    • Nocentini,S. (1995) Comet assay analysis of repair of DNA strand breaks in normal and deficient human cells exposed to radiations and chemicals. Evidence for a repair pathway specificity of DNA ligation. Radiat. Res., 144, 170-180.
    • (1995) Radiat. Res. , vol.144 , pp. 170-180
    • Nocentini, S.1
  • 135
    • 0029991677 scopus 로고    scopus 로고
    • Comet assay demonstrates a higher ultraviolet B sensitivity to DNA damage in dysplastic nevus cells than in common melanocytic nevus cells and foreskin melanocytes
    • Noz,K.C., Bauwens,M., van-Buul,P.P., Vrolijk,H., Schothorst,A.A., Pavel,S., Tanke,H.J. and Vermeer,B.J. (1996) Comet assay demonstrates a higher ultraviolet B sensitivity to DNA damage in dysplastic nevus cells than in common melanocytic nevus cells and foreskin melanocytes. J. Invest. Dermatol., 106, 1198-1202.
    • (1996) J. Invest. Dermatol. , vol.106 , pp. 1198-1202
    • Noz, K.C.1    Bauwens, M.2    Van-Buul, P.P.3    Vrolijk, H.4    Schothorst, A.A.5    Pavel, S.6    Tanke, H.J.7    Vermeer, B.J.8
  • 137
    • 0024544297 scopus 로고
    • Cell proliferation as a requirement for development of the contact effect in Chinese hamster V79 spheroids
    • Olive,P.L. (1989) Cell proliferation as a requirement for development of the contact effect in Chinese hamster V79 spheroids. Radiat. Res., 117, 79-92.
    • (1989) Radiat. Res. , vol.117 , pp. 79-92
    • Olive, P.L.1
  • 138
    • 0027935568 scopus 로고
    • Radiation-induced reoxygeneration in the SCCVII murine tumour: Evidence for a decrease in oxygen consumption and an increase in tumour perfusion
    • Olive,P.L. (1994) Radiation-induced reoxygeneration in the SCCVII murine tumour: evidence for a decrease in oxygen consumption and an increase in tumour perfusion. Radiother. Oncol., 32, 37-46.
    • (1994) Radiother. Oncol. , vol.32 , pp. 37-46
    • Olive, P.L.1
  • 139
    • 0028986423 scopus 로고
    • Detection of hypoxia by measurement of DNA damage in individual cells from spheroids and murine tumours exposed to bioreductive drugs. I. Tirapazamine
    • Olive,P.L. (1995a) Detection of hypoxia by measurement of DNA damage in individual cells from spheroids and murine tumours exposed to bioreductive drugs. I. Tirapazamine. Br. J. Cancer, 71, 529-526.
    • (1995) Br. J. Cancer , vol.71 , pp. 529-1526
    • Olive, P.L.1
  • 140
    • 0029073844 scopus 로고
    • Use of the comet assay to detect hypoxic cells in murine tumours and normal tissues exposed to bioreductive drugs
    • Olive,P.L. (1995b) Use of the comet assay to detect hypoxic cells in murine tumours and normal tissues exposed to bioreductive drugs. Acta Oncol., 34, 301-305.
    • (1995) Acta Oncol. , vol.34 , pp. 301-305
    • Olive, P.L.1
  • 141
    • 0026786492 scopus 로고
    • Tumour growth fraction using the comet assay
    • Olive,P.L. and Banath, J.P. (1992) Tumour growth fraction using the comet assay. Cell Proliferat., 25, 447-457.
    • (1992) Cell Proliferat. , vol.25 , pp. 447-457
    • Olive, P.L.1    Banath, J.P.2
  • 143
    • 0027358748 scopus 로고
    • Induction and rejoining of radiation induced ONA single-strand breaks: 'tail moment' as a function of position in the cell cycle
    • Olive,P.L. and Banath, J.P. (1993b) Induction and rejoining of radiation induced ONA single-strand breaks: 'tail moment' as a function of position in the cell cycle. Mutat. Res., 294, 275-283.
    • (1993) Mutat. Res. , vol.294 , pp. 275-283
    • Olive, P.L.1    Banath, J.P.2
  • 144
    • 0028968957 scopus 로고
    • Radiation-induced DNA double-strand breaks produced in histone-depleted tumor cell nuclei measured using the neutral comet assay
    • Olive,P.L. and Banath, J.P. (1995a) Radiation-induced DNA double-strand breaks produced in histone-depleted tumor cell nuclei measured using the neutral comet assay. Radiat. Res., 142, 144-152.
    • (1995) Radiat. Res. , vol.142 , pp. 144-152
    • Olive, P.L.1    Banath, J.P.2
  • 145
    • 0028884765 scopus 로고
    • Sizing highly fragmented DNA in individual apoptotic cells using the comet assay and a DNA crosslinking agent
    • Olive,P.L. and Banath, J.P. (1995b) Sizing highly fragmented DNA in individual apoptotic cells using the comet assay and a DNA crosslinking agent. Exp. Cell Res., 221, 19-26.
    • (1995) Exp. Cell Res. , vol.221 , pp. 19-26
    • Olive, P.L.1    Banath, J.P.2
  • 146
    • 0025270234 scopus 로고
    • Heterogeneity in radiation-induced DNA damage and repair in tumour and normal cells using the 'comet' assay
    • Olive,P.L., Banath,J.P. and Durand,R.E. (1990a) Heterogeneity in radiation-induced DNA damage and repair in tumour and normal cells using the 'comet' assay. Radiat Res., 122, 86-94.
    • (1990) Radiat Res. , vol.122 , pp. 86-94
    • Olive, P.L.1    Banath, J.P.2    Durand, R.E.3
  • 147
    • 0025305451 scopus 로고
    • Detection of etoposide resistance by measuring DNA damage in individual Chinese hamster cells
    • Olive,P.L., Banath,J.P. and Durand,R.E. (1990b) Detection of etoposide resistance by measuring DNA damage in individual Chinese hamster cells. J. Natl Cancer Inst., 82, 779-783.
    • (1990) J. Natl Cancer Inst. , vol.82 , pp. 779-783
    • Olive, P.L.1    Banath, J.P.2    Durand, R.E.3
  • 148
    • 0025988295 scopus 로고
    • DNA double-strand breaks measured in individual cells subjected to gel electropnoresis
    • Olive,P.L., Wlodeck,D. and Banath,J.P. (1991) DNA double-strand breaks measured in individual cells subjected to gel electropnoresis. Cancer Res., 51, 4671-4676.
    • (1991) Cancer Res. , vol.51 , pp. 4671-4676
    • Olive, P.L.1    Wlodeck, D.2    Banath, J.P.3
  • 149
    • 0026592534 scopus 로고
    • Factors influencing DNA migration from individual cells subjected to gel electrophoresis
    • Olive,P.L., Wlodek,D., Durand,R.E. and Banath,J.P. (1992) Factors influencing DNA migration from individual cells subjected to gel electrophoresis. Exp. Cell Res., 198, 259-267.
    • (1992) Exp. Cell Res. , vol.198 , pp. 259-267
    • Olive, P.L.1    Wlodek, D.2    Durand, R.E.3    Banath, J.P.4
  • 150
    • 0027410453 scopus 로고
    • Cell killing and DNA damage by etoposide in Chinese hamster V79 monolayers and spheroids: Influence of growth kinetics, growth environment and DNA packaging
    • Olive,P.L., Banath,J.P. and Evans,H.H.. (1993a) Cell killing and DNA damage by etoposide in Chinese hamster V79 monolayers and spheroids: influence of growth kinetics, growth environment and DNA packaging. Br. J. Cancer, 67, 522-530.
    • (1993) Br. J. Cancer , vol.67 , pp. 522-530
    • Olive, P.L.1    Banath, J.P.2    Evans, H.H.3
  • 151
    • 0027534567 scopus 로고
    • Gel electrophoresis of individual cells to quantify hypoxic fraction in human breast cancers
    • Olive,P.L. Durand,R.E., Le Riche,J., Olivotto,I. and Jackson,S.M. (1993b) Gel electrophoresis of individual cells to quantify hypoxic fraction in human breast cancers. Cancer Res., 53, 733-736.
    • (1993) Cancer Res. , vol.53 , pp. 733-736
    • Olive, P.L.1    Durand, R.E.2    Le Riche, J.3    Olivotto, I.4    Jackson, S.M.5
  • 152
    • 0027423615 scopus 로고
    • Radiation-induced apoptosis measured in TK6 human B lymphoblasts cells using the comet assay
    • Olive,P.L., Frazer,G. and Banath,J.P. (1993c) Radiation-induced apoptosis measured in TK6 human B lymphoblasts cells using the comet assay. Radiat. Res., 136, 130-136.
    • (1993) Radiat. Res. , vol.136 , pp. 130-136
    • Olive, P.L.1    Frazer, G.2    Banath, J.P.3
  • 153
    • 0028087607 scopus 로고
    • DNA strand breakage and DNA structure influence staining with propidium iodide using the alkaline comet assay
    • Olive,P.L., Banath,J.P. and Fjell,C.D. (1994a) DNA strand breakage and DNA structure influence staining with propidium iodide using the alkaline comet assay. Cytometry, 16, 305-312.
    • (1994) Cytometry , vol.16 , pp. 305-312
    • Olive, P.L.1    Banath, J.P.2    Fjell, C.D.3
  • 154
    • 0028048029 scopus 로고
    • Lack of correlation between radiosensitivity and DNA double-strand break induction or rejoining in six human tumor cell lines
    • Olive,P.L., Banath,J.P. and MacPhail,H.S. (1994b) Lack of correlation between radiosensitivity and DNA double-strand break induction or rejoining in six human tumor cell lines. Cancer Res., 54, 3939-3946.
    • (1994) Cancer Res. , vol.54 , pp. 3939-3946
    • Olive, P.L.1    Banath, J.P.2    MacPhail, H.S.3
  • 155
    • 0028308527 scopus 로고
    • Hypoxic fractions measured in murine tumours and normal tissues using the comet assay
    • Olive,P.L., Vikse,C.M. and Durand,R.E. (1994c) Hypoxic fractions measured in murine tumours and normal tissues using the comet assay. Int. J. Radiat. Oncol. Biol. Phys., 29, 487-491.
    • (1994) Int. J. Radiat. Oncol. Biol. Phys. , vol.29 , pp. 487-491
    • Olive, P.L.1    Vikse, C.M.2    Durand, R.E.3
  • 156
    • 0029740039 scopus 로고    scopus 로고
    • Use of the comet assay to identify cells sensitive to tirapazamine in multicell spheroids and tumours in mice
    • Olive,P.L., Vikse,C.M. and Banath,J.P. (1996) Use of the comet assay to identify cells sensitive to tirapazamine in multicell spheroids and tumours in mice. Cancer Res., 56, 4460-4463.
    • (1996) Cancer Res. , vol.56 , pp. 4460-4463
    • Olive, P.L.1    Vikse, C.M.2    Banath, J.P.3
  • 157
    • 0343852684 scopus 로고    scopus 로고
    • Detection of subpopulations resistant to DNA-damaging agents in spheroids and murine tumours
    • Olive,P.L., Banath,J.P. and Durand,R.E. (1997a) Detection of subpopulations resistant to DNA-damaging agents in spheroids and murine tumours. Mutat. Res.. 375, 157-165.
    • (1997) Mutat. Res.. , vol.375 , pp. 157-165
    • Olive, P.L.1    Banath, J.P.2    Durand, R.E.3
  • 158
    • 0030818472 scopus 로고    scopus 로고
    • Detection of hypoxic cells in a C3H mouse mammary carcinoma using the Comet assay
    • Olive,P.L., Horsman,M.R., Grau,C. and Overgaard,J. (1997b) Detection of hypoxic cells in a C3H mouse mammary carcinoma using the Comet assay. Br. J. Cancer, 76, 694-699.
    • (1997) Br. J. Cancer , vol.76 , pp. 694-699
    • Olive, P.L.1    Horsman, M.R.2    Grau, C.3    Overgaard, J.4
  • 159
    • 0027373136 scopus 로고
    • Analysis of single-cell gel electrophoresis using laser-scanning microscopy
    • O'Neill,K.L., Fairbum,D.W. and Standing,M.D. (1993) Analysis of single-cell gel electrophoresis using laser-scanning microscopy. Mutat. Res., 319, 129-134.
    • (1993) Mutat. Res. , vol.319 , pp. 129-134
    • O'Neill, K.L.1    Fairbum, D.W.2    Standing, M.D.3
  • 160
    • 0021193203 scopus 로고
    • Microelectrophoretic study of radiation-induced DNA damages in individual mammalian cells
    • Östling,O. and Johanson,K.J. (1984) Microelectrophoretic study of radiation-induced DNA damages in individual mammalian cells. Biochem. Biophys. Res. Commun., 123, 291-298.
    • (1984) Biochem. Biophys. Res. Commun. , vol.123 , pp. 291-298
    • Östling, O.1    Johanson, K.J.2
  • 161
    • 0023640885 scopus 로고
    • Bleomycin in contrast to gamma irradiation induces extreme variation of DNA strand breakage from cell to cell
    • Östling,O. and Johanson,K.J. (1987) Bleomycin in contrast to gamma irradiation induces extreme variation of DNA strand breakage from cell to cell. Int. J. Radiat. Biol., 52, 683-691.
    • (1987) Int. J. Radiat. Biol. , vol.52 , pp. 683-691
    • Östling, O.1    Johanson, K.J.2
  • 162
    • 0023232565 scopus 로고
    • DNA damage in clinical radiation therapy studied by microelectrophoresis in single tumour cells
    • Östling,O., Johanson,K.J., Blomquist,E. and Hagelqvist,E. (1987) DNA damage in clinical radiation therapy studied by microelectrophoresis in single tumour cells. Acta Oncol., 26, 45-48.
    • (1987) Acta Oncol. , vol.26 , pp. 45-48
    • Östling, O.1    Johanson, K.J.2    Blomquist, E.3    Hagelqvist, E.4
  • 163
    • 0029562550 scopus 로고
    • Alkaline single cell (comet) assay and genotoxicity monitoring using bullheads and carp
    • Pandrangi,R., Petras,M., Ralph,S. and Vrzoc,M. (1995) Alkaline single cell (comet) assay and genotoxicity monitoring using bullheads and carp. Environ. Mol. Mutagen., 26, 345-356.
    • (1995) Environ. Mol. Mutagen. , vol.26 , pp. 345-356
    • Pandrangi, R.1    Petras, M.2    Ralph, S.3    Vrzoc, M.4
  • 164
    • 0030012151 scopus 로고    scopus 로고
    • Detection of DNA-crosslinking agents with the alkaline comet assay
    • Pfuhler,S. and Wolf,H.U. (1996) Detection of DNA-crosslinking agents with the alkaline comet assay. Environ. Mol. Mutagen., 27, 196-201.
    • (1996) Environ. Mol. Mutagen. , vol.27 , pp. 196-201
    • Pfuhler, S.1    Wolf, H.U.2
  • 165
    • 0028227122 scopus 로고
    • Early effects of benzene exposure in mice. Hematological versus genotoxic effects
    • Plappert,U., Barthel,E., Raddatz,K. and Seidel,HJ. (1994a) Early effects of benzene exposure in mice. Hematological versus genotoxic effects. Arch. Toxicol., 68, 284-290.
    • (1994) Arch. Toxicol. , vol.68 , pp. 284-290
    • Plappert, U.1    Barthel, E.2    Raddatz, K.3    Seidel, H.J.4
  • 167
    • 0029129669 scopus 로고
    • DNA-damage detection in man after radiation exposure-the comet assay-its possible application for human biomonitoring
    • Plappeit,U., Raddatz,K., Roth,S. and Fliedner,T.M. (1995) DNA-damage detection in man after radiation exposure-the comet assay-its possible application for human biomonitoring. Stem Cells Dayt., 13, 215-222.
    • (1995) Stem Cells Dayt. , vol.13 , pp. 215-222
    • Plappeit, U.1    Raddatz, K.2    Roth, S.3    Fliedner, T.M.4
  • 168
    • 0030882595 scopus 로고    scopus 로고
    • Changes in the repair capacity of blood cells as a biomarker for chronic low-dose exposure to ionizing radiation
    • Plappert,U.G., Stocker,B., Fender,H. and Fliedner,T.M. (1997) Changes in the repair capacity of blood cells as a biomarker for chronic low-dose exposure to ionizing radiation. Environ. Mol. Mutagen., 30, 153-160.
    • (1997) Environ. Mol. Mutagen. , vol.30 , pp. 153-160
    • Plappert, U.G.1    Stocker, B.2    Fender, H.3    Fliedner, T.M.4
  • 169
    • 0028792148 scopus 로고
    • Genotoxicity of m-phenylenediamine and 2-aminofluorene in Salmonella typhimurium and human lymphocytes with and without plant activation
    • Plewa,M.J., Wagner,E.D., Yu,T.-W. and Anderson,D. (1995) Genotoxicity of m-phenylenediamine and 2-aminofluorene in Salmonella typhimurium and human lymphocytes with and without plant activation. Environ. Mol. Mutagen., 26, 171-177.
    • (1995) Environ. Mol. Mutagen. , vol.26 , pp. 171-177
    • Plewa, M.J.1    Wagner, E.D.2    Yu, T.-W.3    Anderson, D.4
  • 170
    • 0029967932 scopus 로고    scopus 로고
    • Comet assay study of DNA damage and repair of tumour cells following boron neutron capture irradiation with Fast d(14)+Be neutrons
    • Poller,F., Bauch,T., Sauerwein,W., Bocker,W., Wittig,A. and Streffer,C. (1996) Comet assay study of DNA damage and repair of tumour cells following boron neutron capture irradiation with Fast d(14)+Be neutrons. Int. J. Radiat. Biol., 70, 593-602.
    • (1996) Int. J. Radiat. Biol. , vol.70 , pp. 593-602
    • Poller, F.1    Bauch, T.2    Sauerwein, W.3    Bocker, W.4    Wittig, A.5    Streffer, C.6
  • 171
    • 0030927642 scopus 로고    scopus 로고
    • Induction of DNA damage by risk factors of colon cancer in human colon cells derived from biopsies
    • Pool-Zobel,B.L. and Leucht,U. (1997) Induction of DNA damage by risk factors of colon cancer in human colon cells derived from biopsies. Mutat. Res., 375, 105-115.
    • (1997) Mutat. Res. , vol.375 , pp. 105-115
    • Pool-Zobel, B.L.1    Leucht, U.2
  • 172
    • 0026566088 scopus 로고
    • Systemic genotoxic effects of tobacco-related nitrosamines following oral and inhalational administration to Sprague-Dawley rats
    • Pool-Zobel,B.L., Klein,R.G., Liegibel,U.M., Kuchenmeister,F., Weber,S. and Schmezer,P. (1992) Systemic genotoxic effects of tobacco-related nitrosamines following oral and inhalational administration to Sprague-Dawley rats. Clin. Invest., 70, 299-306.
    • (1992) Clin. Invest. , vol.70 , pp. 299-306
    • Pool-Zobel, B.L.1    Klein, R.G.2    Liegibel, U.M.3    Kuchenmeister, F.4    Weber, S.5    Schmezer, P.6
  • 177
    • 0031418203 scopus 로고    scopus 로고
    • Consumption of vegetables reduces genetic damage in humans: First results of a human intervention trial with carotenoid-rich foods
    • Pool-Zobel,B.L., Bub,A., Muller,H., Wollowski,I. and Rechkemmer,G. (1997) Consumption of vegetables reduces genetic damage in humans: first results of a human intervention trial with carotenoid-rich foods. Carcinogenesis, 18, 1847-1850.
    • (1997) Carcinogenesis , vol.18 , pp. 1847-1850
    • Pool-Zobel, B.L.1    Bub, A.2    Muller, H.3    Wollowski, I.4    Rechkemmer, G.5
  • 178
    • 0030851363 scopus 로고    scopus 로고
    • Genotoxicity monitoring of small bodies of water using two species of tadpoles and the alkaline single cell gel (Comet) assay
    • Ralph,S. and Petras,M. (1997) Genotoxicity monitoring of small bodies of water using two species of tadpoles and the alkaline single cell gel (Comet) assay. Environ. Mol. Mutagen., 29, 418-430.
    • (1997) Environ. Mol. Mutagen. , vol.29 , pp. 418-430
    • Ralph, S.1    Petras, M.2
  • 179
    • 0029957941 scopus 로고    scopus 로고
    • Alkaline single-cell (comet) assay and genotoxicity monitoring using two species of tadpoles
    • Ralph,S., Petras,M., Pandrangi,R. and Vrzoc,M. (1996) Alkaline single-cell (comet) assay and genotoxicity monitoring using two species of tadpoles. Environ. Mol. Mutagen., 28, 112-120.
    • (1996) Environ. Mol. Mutagen. , vol.28 , pp. 112-120
    • Ralph, S.1    Petras, M.2    Pandrangi, R.3    Vrzoc, M.4
  • 180
    • 9844266249 scopus 로고    scopus 로고
    • Single cell gel electrophoresis on peripheral blood leukocytes of patients with oral sqamous cell carcinoma
    • Rao,G.V., Kumar,G.S. and Ahuja,Y.R. (1997) Single cell gel electrophoresis on peripheral blood leukocytes of patients with oral sqamous cell carcinoma. J. Oral Pathol. Med., 26, 377-380.
    • (1997) J. Oral Pathol. Med. , vol.26 , pp. 377-380
    • Rao, G.V.1    Kumar, G.S.2    Ahuja, Y.R.3
  • 181
    • 0342547001 scopus 로고    scopus 로고
    • Evaluation of the genotoxic activity of metronidazole and dimetridazole in human lymphocytes by the Comet assay
    • Re,J.L., DeMeo,M.P., Laget,M., Guiraud,H., Castegnaro,M., Vanelle,P. and Dumenil,G. (1997) Evaluation of the genotoxic activity of metronidazole and dimetridazole in human lymphocytes by the Comet assay. Mutat. Res., 375, 147-155.
    • (1997) Mutat. Res. , vol.375 , pp. 147-155
    • Re, J.L.1    DeMeo, M.P.2    Laget, M.3    Guiraud, H.4    Castegnaro, M.5    Vanelle, P.6    Dumenil, G.7
  • 182
    • 0031230566 scopus 로고    scopus 로고
    • Photogenotoxicity of skin phototumorigenic fluoroquinolone antibiotics detected using the Comet assay
    • Reavy,H.J., Traynor,N.J. and Gibbs,N.K. (1997) Photogenotoxicity of skin phototumorigenic fluoroquinolone antibiotics detected using the Comet assay. Photochem. Photobiol, 66, 368-373.
    • (1997) Photochem. Photobiol , vol.66 , pp. 368-373
    • Reavy, H.J.1    Traynor, N.J.2    Gibbs, N.K.3
  • 183
    • 0029964431 scopus 로고    scopus 로고
    • Genotoxicity of vanadium pentoxide evaluated by the single cell gel electrophoresis assay in human lymphocytes
    • Rojas,E., Valverde,M., Herrera,L.A., Altamirano-Lozano,M. and Ostrosky-Wegman,P. (1996a) Genotoxicity of vanadium pentoxide evaluated by the single cell gel electrophoresis assay in human lymphocytes. Mutat. Res., 359, 77-84.
    • (1996) Mutat. Res. , vol.359 , pp. 77-84
    • Rojas, E.1    Valverde, M.2    Herrera, L.A.3    Altamirano-Lozano, M.4    Ostrosky-Wegman, P.5
  • 184
    • 0030582444 scopus 로고    scopus 로고
    • DNA damage in exfoliated buccal cells of smokers assessed by the single cell gel electrophoresis assay
    • Rojas,E., Valverde,M., Sordo,M. and Ostrosky-Wegman,P. (1996b) DNA damage in exfoliated buccal cells of smokers assessed by the single cell gel electrophoresis assay. Mutat. Res., 370, 115-120.
    • (1996) Mutat. Res. , vol.370 , pp. 115-120
    • Rojas, E.1    Valverde, M.2    Sordo, M.3    Ostrosky-Wegman, P.4
  • 185
    • 0028854128 scopus 로고
    • The single cell microgel electrophoresis assay (comet assay): Technical aspects and applications. Report on the 5th LH Gray Trust Workshop, Institute of Cancer Research, 1994
    • Ross,G.M., McMillan,T.J., Wilcox,P. and Collins,A.R. (1995) The single cell microgel electrophoresis assay (comet assay): technical aspects and applications. Report on the 5th LH Gray Trust Workshop, Institute of Cancer Research, 1994. Mutat. Res., 337, 57-60.
    • (1995) Mutat. Res. , vol.337 , pp. 57-60
    • Ross, G.M.1    McMillan, T.J.2    Wilcox, P.3    Collins, A.R.4
  • 186
    • 0023228268 scopus 로고
    • Visualisation of DNA loops in nucleoids from HeLa cells: Assays from DNA damage and repair
    • Roti-Roti,J.L. and Wright,W.D. (1987) Visualisation of DNA loops in nucleoids from HeLa cells: assays from DNA damage and repair. Cytometry, 8, 461-467.
    • (1987) Cytometry , vol.8 , pp. 461-467
    • Roti-Roti, J.L.1    Wright, W.D.2
  • 187
    • 0029793252 scopus 로고    scopus 로고
    • The effect of lactulose on DNA damage induced by DMH in the colon of human flora-associated rats
    • Rowland,I.R., Beame,C.A., Fischer,R. and Pool-Zobel,B.L. (1996) The effect of lactulose on DNA damage induced by DMH in the colon of human flora-associated rats. Nutr. Cancer, 26, 37-47.
    • (1996) Nutr. Cancer , vol.26 , pp. 37-47
    • Rowland, I.R.1    Beame, C.A.2    Fischer, R.3    Pool-Zobel, B.L.4
  • 188
    • 0001410557 scopus 로고
    • Estimation of single strand breaks in single mammalian cells
    • Hanawalt,P.C., Friedberg,E.C. and Fox,C.F. (eds), Academic Press, New York, NY
    • Rydberg,B. and Johanson,K.J. (1978) Estimation of single strand breaks in single mammalian cells. In Hanawalt,P.C., Friedberg,E.C. and Fox,C.F. (eds), DNA Repair Mechanisms. Academic Press, New York, NY, pp. 465-468.
    • (1978) DNA Repair Mechanisms , pp. 465-468
    • Rydberg, B.1    Johanson, K.J.2
  • 189
    • 0029921918 scopus 로고    scopus 로고
    • The comet assay for the detection of genotoxic damage in the earthworm: A promising tool for assessing the biological hazards of polluted sites
    • Salagovic,J., Gilles,J., Verschaeve,L. and Kalina,I. (1996) The comet assay for the detection of genotoxic damage in the earthworm: a promising tool for assessing the biological hazards of polluted sites. Folia Biol. Praha, 42, 17-21.
    • (1996) Folia Biol. Praha , vol.42 , pp. 17-21
    • Salagovic, J.1    Gilles, J.2    Verschaeve, L.3    Kalina, I.4
  • 190
    • 0030986996 scopus 로고    scopus 로고
    • The cell cycle position influence DNA migration as measured with the alkaline Comet assay in stimulated human lymphocytes
    • Salavogic,J., Maes,A., Van Gorp,U., Verschaeve,L. and Katala,I. (1997) The cell cycle position influence DNA migration as measured with the alkaline Comet assay in stimulated human lymphocytes. Folia Biol. Praha, 43, 79-82.
    • (1997) Folia Biol. Praha , vol.43 , pp. 79-82
    • Salavogic, J.1    Maes, A.2    Van Gorp, U.3    Verschaeve, L.4    Katala, I.5
  • 191
    • 0030816769 scopus 로고    scopus 로고
    • Detection of rodent liver carcinogen genotoxicity by the alkaline single-cell gel electrophoresis (Comet) assay in multiple mouse organs (liver, lung, spleen, kidney and bone marrow)
    • Sasaki,Y.F., Izumiyama,F., Nishidate,E., Matsusaka,N. and Tsuda,S. (1997a) Detection of rodent liver carcinogen genotoxicity by the alkaline single-cell gel electrophoresis (Comet) assay in multiple mouse organs (liver, lung, spleen, kidney and bone marrow). Mutat. Res., 391, 201-204.
    • (1997) Mutat. Res. , vol.391 , pp. 201-204
    • Sasaki, Y.F.1    Izumiyama, F.2    Nishidate, E.3    Matsusaka, N.4    Tsuda, S.5
  • 192
    • 0030861223 scopus 로고    scopus 로고
    • Simple detection of in vivo genotoxicity of pyrimethamine in rodents by the modified alkaline single-cell gel electrophoresis assay
    • Sasaki,Y.F., Izumiyama,F., Nishidate,E., Ohta,T., Ono,T., Matsusaka,N. and Tsuda,S. (1997b) Simple detection of in vivo genotoxicity of pyrimethamine in rodents by the modified alkaline single-cell gel electrophoresis assay. Mutat. Res., 392, 251-259.
    • (1997) Mutat. Res. , vol.392 , pp. 251-259
    • Sasaki, Y.F.1    Izumiyama, F.2    Nishidate, E.3    Ohta, T.4    Ono, T.5    Matsusaka, N.6    Tsuda, S.7
  • 193
    • 0030839678 scopus 로고    scopus 로고
    • Simple detection of chemical mutagens by the alkaline single-cell gel electrophoresis (Comet) assay in multiple mouse organs (liver, lung, spleen, kidney and bone marrow)
    • Sasaki,Y.F., Nishidate,E., Izumiyama,F., Matsusaka,N. and Tsuda,S. (1997c) Simple detection of chemical mutagens by the alkaline single-cell gel electrophoresis (Comet) assay in multiple mouse organs (liver, lung, spleen, kidney and bone marrow). Mutat. Res., 391, 215-231.
    • (1997) Mutat. Res. , vol.391 , pp. 215-231
    • Sasaki, Y.F.1    Nishidate, E.2    Izumiyama, F.3    Matsusaka, N.4    Tsuda, S.5
  • 194
    • 0030988121 scopus 로고    scopus 로고
    • Detection of chemically induced DNA lesions in multiple mouse organs (liver, lung, spleen, kidney and bone marrow) using the alkaline single cell gel electrophoresis (Comet) assay
    • Sasaki,Y.F., Tsuda,S., Izumiyama,F. and Nishidate,E. (1997d) Detection of chemically induced DNA lesions in multiple mouse organs (liver, lung, spleen, kidney and bone marrow) using the alkaline single cell gel electrophoresis (Comet) assay. Mutat. Res., 388, 33-44.
    • (1997) Mutat. Res. , vol.388 , pp. 33-44
    • Sasaki, Y.F.1    Tsuda, S.2    Izumiyama, F.3    Nishidate, E.4
  • 196
    • 0028271775 scopus 로고
    • Tissue-specific induction of mutations by streptozotocin in vivo
    • Schmezer,P., Eckert,C. and Liegibel,U.M. (1994) Tissue-specific induction of mutations by streptozotocin in vivo. Mutat. Res., 307, 495-499.
    • (1994) Mutat. Res. , vol.307 , pp. 495-499
    • Schmezer, P.1    Eckert, C.2    Liegibel, U.M.3
  • 197
    • 0342975064 scopus 로고    scopus 로고
    • The Comet Assay Special Issue
    • Schmezer,P. (ed.) The Comet Assay Special Issue. Mutat. Res., 375, 93-220.
    • Mutat. Res. , vol.375 , pp. 93-220
    • Schmezer, P.1
  • 198
    • 0028211618 scopus 로고
    • Detection of opiate enhanced increases in DNA damage, HPRT mutants and the mutation frequency in human HUT-78 cells
    • Shafer,D. A., Xie,Y. and Falek,A. (1994) Detection of opiate enhanced increases in DNA damage, HPRT mutants and the mutation frequency in human HUT-78 cells. Environ. Mol. Mutagen., 23, 37-44.
    • (1994) Environ. Mol. Mutagen. , vol.23 , pp. 37-44
    • Shafer, D.A.1    Xie, Y.2    Falek, A.3
  • 199
    • 0030009223 scopus 로고    scopus 로고
    • Tirapazamine-induced DNA damage measured using the comet assay correlates with cytotoxicity towards hypoxic tumour cells in vitro
    • Siim,B.G., van-Zijl,P.L. and Brown,J.M. (1996) Tirapazamine-induced DNA damage measured using the comet assay correlates with cytotoxicity towards hypoxic tumour cells in vitro. Br. J. Cancer, 73, 952-960.
    • (1996) Br. J. Cancer , vol.73 , pp. 952-960
    • Siim, B.G.1    Van-Zijl, P.L.2    Brown, J.M.3
  • 200
    • 0030871773 scopus 로고    scopus 로고
    • Tirapazamine-induced cytotoxicity and DNA damage in transplanted tumors: Relationship to tumour hypoxia
    • Siim,B.G., Menke,D.R., Dorie,M.J. and BrownJ.M. (1997) Tirapazamine-induced cytotoxicity and DNA damage in transplanted tumors: relationship to tumour hypoxia. Cancer Res., 57, 2922-2928.
    • (1997) Cancer Res. , vol.57 , pp. 2922-2928
    • Siim, B.G.1    Menke, D.R.2    Dorie, M.J.3    Brown, J.M.4
  • 201
    • 0023919963 scopus 로고
    • A simple technique for quantitation of low levels of DNA damage in individual cells
    • Singh,N.P., McCoy,M.T., Tice,R.R. and Schneider,E.L. (1988) A simple technique for quantitation of low levels of DNA damage in individual cells. Exp. Cell Res., 175, 184-191.
    • (1988) Exp. Cell Res. , vol.175 , pp. 184-191
    • Singh, N.P.1    McCoy, M.T.2    Tice, R.R.3    Schneider, E.L.4
  • 203
    • 0025765751 scopus 로고
    • A microgel electrophoresis technique for the direct quantitation of DNA damage and repair in individual fibroblasts cultured on microscope slides
    • Singh,N.P., Tice,R.R. and Schneider,E.L. (1991) A microgel electrophoresis technique for the direct quantitation of DNA damage and repair in individual fibroblasts cultured on microscope slides. Mutat. Res., 252, 289-296.
    • (1991) Mutat. Res. , vol.252 , pp. 289-296
    • Singh, N.P.1    Tice, R.R.2    Schneider, E.L.3
  • 204
    • 0028092855 scopus 로고
    • Modifications of alkaline microgel electrophoresis for sensitive detection of DNA damage
    • Singh,N.P., Stephens,R.E. and Schneider,E.L. (1994) Modifications of alkaline microgel electrophoresis for sensitive detection of DNA damage. Int. J. Radiat. Biol., 66, 23-28.
    • (1994) Int. J. Radiat. Biol. , vol.66 , pp. 23-28
    • Singh, N.P.1    Stephens, R.E.2    Schneider, E.L.3
  • 206
    • 0342940808 scopus 로고    scopus 로고
    • Detection of MNNG-induced DNA lesions in mammalian cells; validation of Comet assay against DNA unwinding technique, alkaline elution of DNA and chromosomal aberrations
    • Slamenova,D., Gabelova,A., Ruzekova,L., Chalupa,I., Horvathova,E., Farkasova,T., Bozakyova,E. and Stetina,R. (1997) Detection of MNNG-induced DNA lesions in mammalian cells; validation of Comet assay against DNA unwinding technique, alkaline elution of DNA and chromosomal aberrations. Mutat. Res., 383, 243-252.
    • (1997) Mutat. Res. , vol.383 , pp. 243-252
    • Slamenova, D.1    Gabelova, A.2    Ruzekova, L.3    Chalupa, I.4    Horvathova, E.5    Farkasova, T.6    Bozakyova, E.7    Stetina, R.8
  • 207
    • 0028865604 scopus 로고
    • The contribution of excision repair to the DNA effects seen in the alkaline single cell gel test (comet assay)
    • Speit,G. and Hartmann,A. (1995) The contribution of excision repair to the DNA effects seen in the alkaline single cell gel test (comet assay). Mutagenesis, 10, 555-559.
    • (1995) Mutagenesis , vol.10 , pp. 555-559
    • Speit, G.1    Hartmann, A.2
  • 208
    • 0030296410 scopus 로고    scopus 로고
    • Detection of DNA effects in human cells with the comet assay and their relevance for mutagenesis
    • Speit,G., Hanelt,S., Helbig,R., Seidel,A. and Hartmann,A. (1996) Detection of DNA effects in human cells with the comet assay and their relevance for mutagenesis. Toxicol. Lett., 88, 91-98.
    • (1996) Toxicol. Lett. , vol.88 , pp. 91-98
    • Speit, G.1    Hanelt, S.2    Helbig, R.3    Seidel, A.4    Hartmann, A.5
  • 209
    • 0030580936 scopus 로고    scopus 로고
    • Revalidation of the in vitro alkaline elution/rat hepatocyte assay for DNA damage: Improved criteria for assessment of cytotoxicity and genotoxicity and results for 81 compounds
    • Storer,R.D., McKelvey,T.W., Kraynak.A.R., McElia,M.C., Barnum,J.E., Harmon,L.S., Nichols,W.W. and deLuca,J.G. (1996) Revalidation of the in vitro alkaline elution/rat hepatocyte assay for DNA damage: improved criteria for assessment of cytotoxicity and genotoxicity and results for 81 compounds. Mutat. Res., 368, 59-101.
    • (1996) Mutat. Res. , vol.368 , pp. 59-101
    • Storer, R.D.1    McKelvey, T.W.2    Kraynak, A.R.3    McElia, M.C.4    Barnum, J.E.5    Harmon, L.S.6    Nichols, W.W.7    DeLuca, J.G.8
  • 210
    • 0028123570 scopus 로고
    • Measuring DNA damage in individual cells of heterogeneous mixtures: A novel application of an immunological typing technique
    • Strauss,G.H.S., Peters,W.P. and Everson,R.B. (1994) Measuring DNA damage in individual cells of heterogeneous mixtures: a novel application of an immunological typing technique. Mutat. Res., 304, 211-216.
    • (1994) Mutat. Res. , vol.304 , pp. 211-216
    • Strauss, G.H.S.1    Peters, W.P.2    Everson, R.B.3
  • 211
    • 0029588416 scopus 로고
    • Bleomycin-induced DNA damage and repair in wild-type and thymidine kinase-deficient Friend mouse erythroleukaemia cells
    • Sweetman,S.F., McKenna,P.G. and McKelvey-Martin,V.J. (1995) Bleomycin-induced DNA damage and repair in wild-type and thymidine kinase-deficient Friend mouse erythroleukaemia cells. Br. J. Biomed. Sci., 52, 257-265.
    • (1995) Br. J. Biomed. Sci. , vol.52 , pp. 257-265
    • Sweetman, S.F.1    McKenna, P.G.2    McKelvey-Martin, V.J.3
  • 212
    • 0031050629 scopus 로고    scopus 로고
    • Effect of antioxidant vitamin supplementation on DNA damage and repair in human lymphoblastoid cells
    • Sweetman,S.F., Strain,J.J. and McKelvey-Martin,V.J. (1997) Effect of antioxidant vitamin supplementation on DNA damage and repair in human lymphoblastoid cells. Nutr. Cancer, 27, 122-130.
    • (1997) Nutr. Cancer , vol.27 , pp. 122-130
    • Sweetman, S.F.1    Strain, J.J.2    McKelvey-Martin, V.J.3
  • 214
    • 0030596086 scopus 로고    scopus 로고
    • In vitro mutagenicity and genotoxicity study of 1,2-dichloroethylene, 1,1,2-trichloroethane, 1,3-dichloropropane, 1,2,3-trichloropropane and 1,1,3-trichloropropene, using the micronucleaus test and the alkaline single cell gel electrophoresis technique (comet assay) in human lymphocytes
    • Tafazoli,M. and Kirsch-Volders,M. (1996) In vitro mutagenicity and genotoxicity study of 1,2-dichloroethylene, 1,1,2-trichloroethane, 1,3-dichloropropane, 1,2,3-trichloropropane and 1,1,3-trichloropropene, using the micronucleaus test and the alkaline single cell gel electrophoresis technique (comet assay) in human lymphocytes. Mutat. Res., 371, 185-202.
    • (1996) Mutat. Res. , vol.371 , pp. 185-202
    • Tafazoli, M.1    Kirsch-Volders, M.2
  • 216
    • 0002987035 scopus 로고
    • The single cell gel/comet assay: A microgel electrophoretic technique for the detection of DNA damage and repair in individual cells
    • Phillips,D.H. and Venitt,S. (eds), Bios Scientific Publishers, Oxford, UK
    • Tice,R.R. (1995) The single cell gel/comet assay: a microgel electrophoretic technique for the detection of DNA damage and repair in individual cells. In Phillips,D.H. and Venitt,S. (eds), Environmental Mutagenesis. Bios Scientific Publishers, Oxford, UK, pp. 315-339.
    • (1995) Environmental Mutagenesis , pp. 315-339
    • Tice, R.R.1
  • 217
    • 85038549784 scopus 로고
    • The single cell gel electrophoresis/ comet assay: A potential tool for detecting radiation-induced DNa damage in humans
    • Fliedner,T.M., Cronkite,E.P. and Bond,V.P. (eds), Alphamed Press, Dayton, OH
    • Tice,R.R. and Strauss,G.H.S. (1995a) The single cell gel electrophoresis/ comet assay: a potential tool for detecting radiation-induced DNA damage in humans. In Fliedner,T.M., Cronkite,E.P. and Bond,V.P. (eds), Assessment of Radiation Effects by Molecular and Cellular Approaches. Alphamed Press, Dayton, OH.
    • (1995) Assessment of Radiation Effects by Molecular and Cellular Approaches
    • Tice, R.R.1    Strauss, G.H.S.2
  • 218
    • 0029102911 scopus 로고
    • The single cell gel electrophoresis/comet assay: A potential tool for detecting radiation-induced DNA damage in humans
    • Tice,R.R. and Strauss,G.H. (1995b) The single cell gel electrophoresis/comet assay: a potential tool for detecting radiation-induced DNA damage in humans. Stem Cells Dayt., 13, 207-214.
    • (1995) Stem Cells Dayt. , vol.13 , pp. 207-214
    • Tice, R.R.1    Strauss, G.H.2
  • 219
    • 0025618481 scopus 로고
    • The single cell gel assay: A sensitive technique for evaluating intercellular differences in DNA damage and repair
    • Sutherland,B.M. and Woodhead,A.D. (eds), Plenum Press, New York, NY
    • Tice,P.R., Andrews,P.W. and Singh,N.P. (1990) The single cell gel assay: a sensitive technique for evaluating intercellular differences in DNA damage and repair. In Sutherland,B.M. and Woodhead,A.D. (eds), DNA Damage and Repair in Human Tissues. Plenum Press, New York, NY, pp. 291-301.
    • (1990) DNA Damage and Repair in Human Tissues , pp. 291-301
    • Tice, P.R.1    Andrews, P.W.2    Singh, N.P.3
  • 220
    • 0026005914 scopus 로고
    • The single cell gel (SCG) assay: An electrophoretic technique for the detection of DNA damage in individual cells
    • Witmer,C.R., Snyder,R.R., Jollow,D.J., Kalf.G.F., Kocsis,J.J. and Sipes,I.G. (eds), Plenum Press, New York, NY
    • Tice,R.R., Andrews,P.W., Hirai,O. and Singh,N.P. (1991) The single cell gel (SCG) assay: an electrophoretic technique for the detection of DNA damage in individual cells. In Witmer,C.R., Snyder,R.R., Jollow,D.J., Kalf.G.F., Kocsis,J.J. and Sipes,I.G. (eds), Biological Reactive Intermediates IV, Molecular and Cellular Effects and Their Impact on Human Health. Plenum Press, New York, NY, pp. 157-164.
    • (1991) Biological Reactive Intermediates IV, Molecular and Cellular Effects and Their Impact on Human Health , pp. 157-164
    • Tice, R.R.1    Andrews, P.W.2    Hirai, O.3    Singh, N.P.4
  • 221
    • 3643118838 scopus 로고
    • DNA damage in normal and choline-deticient male B6C3F1 mice treated by oral gavage with sodium arsenite
    • Tice,R.R., Schmitt,M.T., Andrews,P.W. and Yager,J.W. (1994) DNA damage in normal and choline-deticient male B6C3F1 mice treated by oral gavage with sodium arsenite. Environ. Mol. Mutagen., 23, 66.
    • (1994) Environ. Mol. Mutagen. , vol.23 , pp. 66
    • Tice, R.R.1    Schmitt, M.T.2    Andrews, P.W.3    Yager, J.W.4
  • 222
    • 0026602463 scopus 로고
    • High-dose combination alkylating agents with autologous bone marrow support in patients with breast cancer: Preliminary assessment of DNA damage in individual peripheral blood lymphocytes using the single cell gel electrophoresis assay
    • Tice,R.R., Strauss,G.H.S. and Peters,W.P. (1992) High-dose combination alkylating agents with autologous bone marrow support in patients with breast cancer: preliminary assessment of DNA damage in individual peripheral blood lymphocytes using the single cell gel electrophoresis assay. Mutat. Res., 271, 101-113.
    • (1992) Mutat. Res. , vol.271 , pp. 101-113
    • Tice, R.R.1    Strauss, G.H.S.2    Peters, W.P.3
  • 224
    • 0028510657 scopus 로고
    • Study of DNA damage and heterogenicity of cells by a gel microelectrophoresis method
    • Tronov,V.A., Grin'ko,E.V., Afanas'ev,G.G. and Filippovich,I.V. (1994) Study of DNA damage and heterogenicity of cells by a gel microelectrophoresis method. Biofizika, 39, 810-900.
    • (1994) Biofizika , vol.39 , pp. 810-900
    • Tronov, V.A.1    Grin'ko, E.V.2    Afanas'ev, G.G.3    Filippovich, I.V.4
  • 225
    • 0030570557 scopus 로고    scopus 로고
    • Benzene-induced genotoxicity in mice in vivo detected by the alkaline comet assay: Reduction by CYP2E1 inhibition
    • Tuo,J., Loft,S., Thomsen,M.S. and Poulsen,H.E. (1996) Benzene-induced genotoxicity in mice in vivo detected by the alkaline comet assay: reduction by CYP2E1 inhibition. Mutat. Res., 368, 213-219.
    • (1996) Mutat. Res. , vol.368 , pp. 213-219
    • Tuo, J.1    Loft, S.2    Thomsen, M.S.3    Poulsen, H.E.4
  • 226
    • 0027957681 scopus 로고
    • Radiosensitivity of CD45RO+ memory and CD45RO - Naive T cells in culture
    • Uzawa,A., Suzuki,G., Nakata,Y., Akashi,M., Ohyama,H. and Akanuma,A. (1994) Radiosensitivity of CD45RO+ memory and CD45RO - naive T cells in culture. Radiat. Res., 137, 25-33.
    • (1994) Radiat. Res. , vol.137 , pp. 25-33
    • Uzawa, A.1    Suzuki, G.2    Nakata, Y.3    Akashi, M.4    Ohyama, H.5    Akanuma, A.6
  • 227
    • 0030051893 scopus 로고    scopus 로고
    • Demonstration of benzo[a]pyrene-induced DNA damage in mice by alkaline single cell gel electrophoresis: Evidence for strand breaks in liver but not in lymphocytes and bone marrow
    • Vaghef,H., Wisen,A.C. and Hellman,B. (1996) Demonstration of benzo[a]pyrene-induced DNA damage in mice by alkaline single cell gel electrophoresis: evidence for strand breaks in liver but not in lymphocytes and bone marrow. Pharmacol. Toxicol., 78, 37-43.
    • (1996) Pharmacol. Toxicol. , vol.78 , pp. 37-43
    • Vaghef, H.1    Wisen, A.C.2    Hellman, B.3
  • 229
    • 0030851297 scopus 로고    scopus 로고
    • Comparative evaluation of the in vitro micronucleus test and the alkaline single cell gel electrophoresis assay for the detection of DNA damaging agents: Genotoxic effects of cobalt powder, tungsten carbide and cobalt-tungsten carbide
    • Van Goethem,F., Lison,D. and Kirsch-Volders,M. (1997) Comparative evaluation of the in vitro micronucleus test and the alkaline single cell gel electrophoresis assay for the detection of DNA damaging agents: genotoxic effects of cobalt powder, tungsten carbide and cobalt-tungsten carbide. Mutat. Res., 392, 31-43.
    • (1997) Mutat. Res. , vol.392 , pp. 31-43
    • Van Goethem, F.1    Lison, D.2    Kirsch-Volders, M.3
  • 230
    • 0026751636 scopus 로고
    • Assessment of radiation-induced DNA damage in human blood lymphocytes using the single cell gel electrophoresis technique
    • Vijayalaxmi, Tice,R.R. and Strauss,G.H.S. (1992) Assessment of radiation-induced DNA damage in human blood lymphocytes using the single cell gel electrophoresis technique. Mutat. Res., 271, 243-252.
    • (1992) Mutat. Res. , vol.271 , pp. 243-252
    • Vijayalaxmi1    Tice, R.R.2    Strauss, G.H.S.3
  • 231
    • 0027257141 scopus 로고
    • An analysis of gamma-ray-induced DNA damage in human blood leukocytes, lymphocytes and granulocytes
    • Vijayalaxmi, Strauss,G.H.S. and Tice,R.R. (1993) An analysis of gamma-ray-induced DNA damage in human blood leukocytes, lymphocytes and granulocytes. Mutat. Res., 292, 123-128.
    • (1993) Mutat. Res. , vol.292 , pp. 123-128
    • Vijayalaxmi1    Strauss, G.H.S.2    Tice, R.R.3
  • 233
    • 0029032680 scopus 로고
    • 6-guanine DNA adducts, DNA strand breaks and mutant frequencies in the hypoxanthine guarune phosphoribosyltransferase gene in T-lymphocytes
    • 6-guanine DNA adducts, DNA strand breaks and mutant frequencies in the hypoxanthine guarune phosphoribosyltransferase gene in T-lymphocytes. Carcinogenessis, 16, 1473-1481.
    • (1995) Carcinogenessis , vol.16 , pp. 1473-1481
    • Vodicka, P.1    Bastlova, T.2    Vodickova, L.3    Peterkova, K.4    Lambert, B.5    Hemminki, K.6
  • 234
    • 0028020158 scopus 로고
    • Response of fibroblast cultures from ataxia-telangiectasia patients to reactive oxygen species generated during inflammatory reactions
    • Ward,A.J., Olive,P.L. Burr,A.H. and Rosin,M.P. (1994) Response of fibroblast cultures from ataxia-telangiectasia patients to reactive oxygen species generated during inflammatory reactions. Environ. Mol. Mittagen., 24, 103-111.
    • (1994) Environ. Mol. Mittagen. , vol.24 , pp. 103-111
    • Ward, A.J.1    Olive, P.L.2    Burr, A.H.3    Rosin, M.P.4
  • 235
    • 0027368131 scopus 로고
    • A sensitivity to oxidative stress is linked to chromosome II but is not due to a difference in single-strand DNA damage or repair
    • Ward,A.J., Rosin,M.P., Olive,P.L. and Burr,A.H. (1993) A sensitivity to oxidative stress is linked to chromosome II but is not due to a difference in single-strand DNA damage or repair. Mutat. Res., 294, 299-308.
    • (1993) Mutat. Res. , vol.294 , pp. 299-308
    • Ward, A.J.1    Rosin, M.P.2    Olive, P.L.3    Burr, A.H.4
  • 236
    • 0030920810 scopus 로고    scopus 로고
    • Comet assay studies on the activation of two diaziridinylbenzoquinones in K562 cells
    • Ward,T.H., Butler,J., Shahbakhti,H. and Richards,J.T. (1997) Comet assay studies on the activation of two diaziridinylbenzoquinones in K562 cells. Biochem. Pharmacol., 53, 1115-1121.
    • (1997) Biochem. Pharmacol. , vol.53 , pp. 1115-1121
    • Ward, T.H.1    Butler, J.2    Shahbakhti, H.3    Richards, J.T.4
  • 237
    • 0029940104 scopus 로고    scopus 로고
    • Analysis of DNA damage recovery processes in the adaptive response to ionizing radiation in human lymphocytes
    • Wojcik,A., Sauer,C., Zolzer,F., Bauch,T. and Muller,W.U. (1996) Analysis of DNA damage recovery processes in the adaptive response to ionizing radiation in human lymphocytes. Mutagenesis, 11, 291-297.
    • (1996) Mutagenesis , vol.11 , pp. 291-297
    • Wojcik, A.1    Sauer, C.2    Zolzer, F.3    Bauch, T.4    Muller, W.U.5
  • 238
    • 0029908264 scopus 로고    scopus 로고
    • Anti-CD38 prevents the development of the adaptive response induced by X-rays in human lymphocytes
    • Wojewodzka,M., Kruszewski,M. and Szumiel,I. (1996) Anti-CD38 prevents the development of the adaptive response induced by X-rays in human lymphocytes. Mutagenesis, 11, 593-596.
    • (1996) Mutagenesis , vol.11 , pp. 593-596
    • Wojewodzka, M.1    Kruszewski, M.2    Szumiel, I.3
  • 239
    • 0030611982 scopus 로고    scopus 로고
    • Effect of signal transduction inhibition in adapted lymphocytes: Micronuclei frequency and DNA repair
    • Wojewodzka,M., Kruszewski,M. and Szumiel,I. (1997) Effect of signal transduction inhibition in adapted lymphocytes: micronuclei frequency and DNA repair. Int. J. Radiat. Biol., 71, 245-252.
    • (1997) Int. J. Radiat. Biol. , vol.71 , pp. 245-252
    • Wojewodzka, M.1    Kruszewski, M.2    Szumiel, I.3
  • 240
    • 0030840012 scopus 로고    scopus 로고
    • Measurement of menadione-mediated DNA damage in human lymphocytes using the Comet assay
    • Woods,J.A., Young,A.J., Gilmore,I.T., Morris,A. and Bilton,R.F. (1997) Measurement of menadione-mediated DNA damage in human lymphocytes using the Comet assay. Free Radical Res., 26, 113-124.
    • (1997) Free Radical Res. , vol.26 , pp. 113-124
    • Woods, J.A.1    Young, A.J.2    Gilmore, I.T.3    Morris, A.4    Bilton, R.F.5
  • 241
    • 3643089682 scopus 로고
    • Urinary excretion kinetics and DNA damage in normal and choline deficient male B6C3F1 mice treated once by oral gavage with sodium arsenite
    • Yager,J.W., Schmitt,M.T., Andrews,P.W., Tice,R.R. and Crecelius,E. (1994) Urinary excretion kinetics and DNA damage in normal and choline deficient male B6C3F1 mice treated once by oral gavage with sodium arsenite. Environ. Mol. Mutagen., 23 (suppl. 23), 75.
    • (1994) Environ. Mol. Mutagen. , vol.23 , Issue.23 SUPPL. , pp. 75
    • Yager, J.W.1    Schmitt, M.T.2    Andrews, P.W.3    Tice, R.R.4    Crecelius, E.5
  • 242
    • 0031011221 scopus 로고    scopus 로고
    • The genetic toxicity of time: Importance of DNA-unwinding time to the outcome of single-cell gel electrophoresis assays
    • Yendle,J.E., Tinwell,H., Elliott,B.M. and Ashby,J. (1997) The genetic toxicity of time: importance of DNA-unwinding time to the outcome of single-cell gel electrophoresis assays. Mutat. Res., 375, 125-136.
    • (1997) Mutat. Res. , vol.375 , pp. 125-136
    • Yendle, J.E.1    Tinwell, H.2    Elliott, B.M.3    Ashby, J.4
  • 243
    • 0030004193 scopus 로고    scopus 로고
    • Reduction of tumour hypoxia and inhibition of DNA repair by nicotinamide after irradiation of SCCVII murine tumours and normal tissues
    • Zheng,H. and Olive,O.L. (1996) Reduction of tumour hypoxia and inhibition of DNA repair by nicotinamide after irradiation of SCCVII murine tumours and normal tissues. Cancer. Res., 56, 2801-2808.
    • (1996) Cancer. Res. , vol.56 , pp. 2801-2808
    • Zheng, H.1    Olive, O.L.2
  • 244
    • 0030941613 scopus 로고    scopus 로고
    • Influence of oxygen on radiation-induced DNA damage in testicular cells of C3H mice
    • Zheng,H. and Olive,P.L. (1997) Influence of oxygen on radiation-induced DNA damage in testicular cells of C3H mice. Int. J. Radiai. Biol., 71, 275-282.
    • (1997) Int. J. Radiai. Biol. , vol.71 , pp. 275-282
    • Zheng, H.1    Olive, P.L.2
  • 245
    • 0029803540 scopus 로고    scopus 로고
    • DNA strand breaks and poly(ADP-ribose) polymerase activation induced by crystalline nickel subsulfide in MRC-5 lung fibroblast cells
    • Zhuang,Z.X., Shen,Y., Shen,H.M., Ng,V. and Ong,C.N. (1996) DNA strand breaks and poly(ADP-ribose) polymerase activation induced by crystalline nickel subsulfide in MRC-5 lung fibroblast cells. Hum. Exp. Toxicol., 15, 891-897.
    • (1996) Hum. Exp. Toxicol. , vol.15 , pp. 891-897
    • Zhuang, Z.X.1    Shen, Y.2    Shen, H.M.3    Ng, V.4    Ong, C.N.5


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