Mouse pulmonary dose- and time course-responses induced by exposure to multi-walled carbon nanotubes

Toxicology

Volumn 269, Issue 2-3, 2010, Pages 136-147

  Porter, Dale W ^a,b   Hubbs, Ann F ^a   Mercer, Robert R ^a,b   Wu, Nianqiang ^c   Wolfarth, Michael G ^a   Sriram, Krishnan ^a   Leonard, Stephen ^a   Battelli, Lori ^a   Schwegler Berry, Diane ^a   Friend, Sherry ^a   Andrew, Michael ^a   Chen, Bean T ^a   Tsuruoka, Shuji ^d   Endo, Morinobu ^d   Castranova, Vincent ^a,b  

^a NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTH   (United States)

^b WEST VIRGINIA UNIVERSITY   (United States)

^c West Virginia University   (United States)

^d SHINSHU UNIVERSITY   (Japan)

Author keywords

Fibrosis; Inflammation; Multi walled carbon nanotubes

Indexed keywords

MULTI WALLED NANOTUBE;

ANIMAL EXPERIMENT; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ECOTOXICOLOGY; ELECTRON SPIN RESONANCE; ENVIRONMENTAL EXPOSURE; HISTOPATHOLOGY; IN VIVO STUDY; LUNG FIBROSIS; LUNG INJURY; LUNG LAVAGE; LUNG TOXICITY; MALE; MOUSE; NANOTECHNOLOGY; NONHUMAN; PNEUMONIA; PRIORITY JOURNAL; RISK ASSESSMENT; TRANSMISSION ELECTRON MICROSCOPY; X RAY PHOTOELECTRON SPECTROSCOPY;

ANIMALS; BRONCHOALVEOLAR LAVAGE FLUID; DOSE-RESPONSE RELATIONSHIP, DRUG; INHALATION EXPOSURE; LUNG; MALE; MICE; MICE, INBRED C57BL; NANOTUBES, CARBON; PNEUMONIA; TOXICITY TESTS;

MUS;

EID: 77949914991     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2009.10.017     Document Type: Article

References (52)

1. Ackermann M.R. Chronic inflammation and wound healing. Pathologic Basis of Veterinary Disease 2007, 153-191. Mosby Elsevier, St. Louis. M. Zachary (Ed.).
2. Ago H., Kugler T., Cacialli F., Salaneck W.R., Shaffer M.S.P., Windle A.H., Friend R.H. Work functions and surface functional groups of multiwall carbon nanotubes. J. Phys. Chem. B 1999, 103:8116-8121.
3. Baluk P., McDonald D.M. Markers for microscopic imaging of lymphangiogenesis and angiogenesis. Ann. N. Y. Acad. Sci. 2008, 1131:1-12.
4. Castranova V., Vallyathan V. Silicosis and coal workers' pneumoconiosis. Environ. Health Perspect. 108 Suppl. 2000, 4:675-684.
5. Chen P. Electronic structure and optical limiting behavior of carbon nanotubes. Phys. Rev. Lett. 1999, 82:2548-2551.
6. Deng X., Jia G., Wang H., Sun H., Wang X., Yang S., Wang T., Liu Y. Translocation and fate of multi-walled carbon nanotubes in vivo. Carbon 2007, 45:1419-1424.
7. Dixon D., Herbert R.A., Sills R.C., Boorman G.A. Lungs, pleura, and mediastinum. Pathology of the Mouse 1999, 293-332. Cache River Press, Vienna, IL. R.R. Maronpot, G.A. Boorman, B.W. Gaul (Eds.).
8. Donaldson K., Tran C.L. An introduction to the short-term toxicology of respirable industrial fibres. Mutat. Res. 2004, 553:5-9.
9. Donaldson K., Aitken R., Tran L., Stone V., Duffin R., Forrest G., Alexander A. Carbon nanotubes: a review of their properties in relation to pulmonary toxicology and workplace safety. Toxicol. Sci. 2006, 92:5-22.
10. Endo M., Strano M.S., Ajayan P.M. Potential applications of carbon nanotubes. Carbon Nanotubes 2008, 111:13-61.
11. Epler G.R., Colby T.V., McLoud T.C., Carrington C.B., Gaensler E.A. Bronchiolitis obliterans organizing pneumonia. N. Engl. J. Med. 1985, 312:152-158.
12. Epler G.R. Bronchiolitis obliterans organizing pneumonia: definition and clinical features. Chest 1992, 102:2S-6S.
13. Epler G.R. Bronchiolitis obliterans organizing pneumonia. Arch. Intern. Med. 2001, 161:158-164.
14. Faul J.L., Berry G.J., Colby T.V., Ruoss S.J., Walter M.B., Rosen G.D., Raffin T.A. Thoracic lymphangiomas, lymphangiectasis, lymphangiomatosis, and lymphatic dysplasia syndrome. Am. J. Respir. Crit. Care Med. 2000, 161:1037-1046.
15. Felten A., Bittencourt C., Pireaux J.J. Gold clusters on oxygen plasma functionalized carbon nanotubes: XPS and TEM studies. Nanotechnology 2006, 17:1954-1959.
16. Fenoglio I., Tomatis M., et al. Reactivity of carbon nanotubes: free radical generation or scavenging activity?. Free Radic. Biol. Med. 2006, 40(7):1227-1233.
17. Galer D.M., Leung H.W., Sussman R.G., Trzos R.J. Scientific and practical considerations for the development of occupational exposure limits (OELs) for chemical substances. Regul. Toxicol. Pharmacol. 1992, 15:291-306.
18. Han J.H., Lee E.J., Lee J.H., So K.P., Lee Y.H., Bae G.N., Lee S.B., Ji J.H., Cho M.H., Yu I.J. Monitoring multiwalled carbon nanotube exposure in carbon nanotube research facility. Inhal. Toxicol. 2008, 20:741-749.
19. Harmsen A.G., Muggenburg B.A., Snipes M.B., Bice D.E. The role of macrophages in particle translocation from lungs to lymph nodes. Science 1985, 230:1277-1280.
20. Harmsen A.G., Mason M.J., Muggenburg B.A., Gillett N.A., Jarpe M.A., Bice D.E. Migration of neutrophils from lung to tracheobronchial lymph node. J. Leukoc. Biol. 1987, 41:95-103.
21. Harding A.H., Darnton A., Wegerdt J., McElvenny D. Mortality among British asbestos workers undergoing regular medical examinations (1971-2005). Occup. Environ. Med. 2009, 66(7):487-495.
22. Henderson R.F., Benson J.M., Hahn F.F., Hobbs C.H., Jones R.K., Mauderly J.L., McClellan R.O., Pickrell J.A. New approaches for the evaluation of pulmonary toxicity: bronchoalveolar lavage fluid analysis. Fundam. Appl. Toxicol. 1985, 5:451-458.
23. Johnson L.A., Clasper S., Holt A.P., Lalor P.F., Baban D., Jackson D.G. An inflammation-induced mechanism for leukocyte transmigration across lymphatic vessel endothelium. J. Exp. Med. 2006, 203:2763-2777.
24. Johnson L.A., Jackson D.G. Cell traffic and the lymphatic endothelium. Ann. N. Y. Acad. Sci. 2008, 1131:119-133.
25. Lison D., Muller J. To the Editor. Toxicol. Sci. 2008, 101:179-180.
26. Littell R.C., Milliken G.A., Stroup W.W., Wolfinger R.D. SAS System for Mixed Models 1996, SAS Institute Inc., Cary, NC.
27. Maynard A.D., Baron P.A., Foley M., Shvedova A.A., Kisin E.R., Castranova V. Exposure to carbon nanotube material: aerosol release during the handling of unrefined single-walled carbon nanotube material. J. Toxicol. Environ. Health A 2004, 67:87-107.
28. McDonald J., Mitchell L. To the Editor. Toxicol. Sci. 2008, 101:181-182.
29. Mercer R.R., Scabilloni J., Wang L., Kisin E., Murray A.R., Schwegler-Berry D., Shvedova A.A., Castranova V. Alteration of deposition pattern and pulmonary response as a result of improved dispersion of aspirated single-walled carbon nanotubes in a mouse model. Am. J. Physiol. Lung Cell. Mol. Physiol. 2008, 294(1):L87-L97.
30. Mitchell L.A., Gao J., Wal R.V., Gigliotti A., Burchiel S.W., McDonald J.D. Pulmonary and systemic immune response to inhaled multiwalled carbon nanotubes. Toxicol. Sci. 2007, 100:203-214.
31. Morrow P.E. Lymphatic drainage of the lung in dust clearance. Ann. N. Y. Acad. Sci. 1972, 200:46-65.
32. Mossman B.T., Churg A. Mechanisms in the pathogenesis of asbestosis and silicosis. Am. J. Respir. Crit. Care Med. 1998, 157:1666-1680.
33. Muller J., Huaux F., Moreau N., Misson P., Heilier J.F., Delos M., Arras M., Fonseca A., Nagy J.B., Lison D. Respiratory toxicity of multi-wall carbon nanotubes. Toxicol. Appl. Pharmacol. 2005, 207:221-231.
34. NIOSH. NIOSH Method 7300 Elements by ICP (nitric/perchloric acid ashing).
35. Oberdorster G., Maynard A., Donaldson K., Castranova V., Fitzpatrick J., Ausman K., Carter J., Karn B., Kreyling W., Lai D., Olin S., Monteiro-Riviere N., Warheit D., Yang H., Group A.r.f.t.I.R.F.R.S.I.N.T.S.W. Principles for characterizing the potential human health effects from exposure to nanomaterials: elements of a screening strategy. Part. Fibre Toxicol. 2005, 2:8.
36. Ohtani O., Ohtani Y. Organization and developmental aspects of lymphatic vessels. Arch. Histol. Cytol. 2008, 71:1-22.
37. Pulskamp K., Diabaté S., et al. Carbon nanotubes show no sign of acute toxicity but induce intracellular reactive oxygen species in dependence on contaminants. Toxicol. Lett. 2007, 168(1):58-74.
38. Pinault M, Mayne-L'Hermite M., Reynaud C., Pichot V., Launois P., Ballutaud D. Growth of multiwalled carbon nanotubes during the initial stages of aerosol-assisted CCVD. Carbon 2005, 43:2968-2976.
39. Phalen R.F. Basic morphology and physiology of the respiratory tract. Inhalation Studies: Foundattions and Techniques 1984, CRC Press, Boca Raton, pp. 33-75.
40. Porter D.W., Hubbs A.F., Baron P.A., Millecchia L.L., Wolfarth M.G., Battelli L.A., Schwegler-Berry D.E., Beighley C.M., Andrew M.E., Castranova V. Pulmonary toxicity of expancel microspheres in the rat. Toxicol. Pathol. 2007, 35:702-714.
41. Porter D., Sriram K., Wolfarth M., Jefferson A., Schwegler-Berry D., Andrew M.E., Castranova V. A biocompatible medium for nanoparticle dispersion. Nanotoxicology 2008, 2:144-154.
42. Porter D.W., Wolfarth M.G., Chen B.T., McKinney W., Hubbs A.F., Battelli L., Andrew A., Frazier D.G., Castranova V. Pulmonary toxicity of inhaled multi-walled carbon nanotubes. Toxicologist 2009, 108:457.
43. Ryu J.H., Myers J.L., Swensen S.J. Bronchiolar disorders. Am. J. Respir. Crit. Care Med. 2003, 168:1277-1292.
44. Shvedova A.A., Kisin E.R., Mercer R., Murray A.R., Johnson V.J., Potapovich A.I., Tyurina Y.Y., Gorelik O., Arepalli S., Schwegler-Berry D., Hubbs A.F., Antonini J., Evans D.E., Ku B.K., Ramsey D., Maynard A., Kagan V.E., Castranova V., Baron P. Unusual inflammatory and fibrogenic pulmonary responses to single-walled carbon nanotubes in mice. Am. J. Physiol. Lung Cell. Mol. Physiol. 2005, 289:L698-L708.
45. Shvedova A.A., Kisin E., Murray A.R., Johnson V.J., Gorelik O., Arepalli S., Hubbs A.F., Mercer R.R., Keohavong P., Sussman N., Jin J., Yin J., Stone S., Chen B.T., Deye G., Maynard A., Castranova V., Baron P.A., Kagan V.E. Inhalation vs. aspiration of single-walled carbon nanotubes in C57BL/6 mice: inflammation, fibrosis, oxidative stress, and mutagenesis. Am. J. Physiol. Lung Cell. Mol. Physiol. 2008, 295:L552-L565.
46. Stankovich S. Stable aqueous dispersions of graphitic nanoplatelets via the reduction of exfoliated graphite oxide in the presence of poly(sodium 4-styrenesulfonate). J. Mater. Chem. 2006, 16:155-158.
47. Stone K.C., Mercer R.R., Gehr P., Stockstill B., Crapo J.D. Allometric relationships of cell numbers and size in the mammalian lung. Am. J. Respir. Cell Mol. Biol. 1992, 6:235-243.
48. Tenne R., Remskar M., Enyashin A., Seifert G. Inorganic nanotubes and fullerene-like structures (IF). Carbon Nanotubes 2008, 111:631-671.
49. Trosic I., Matausic-Pisl M., Hors N. Pathways and quantification of insoluble particles in the lung compartments of the rat. Int. J. Hyg. Environ. Health 2000, 203:39-43.
50. Warheit D.B., Laurence B.R., Reed K.L., Roach D.H., Reynolds G.A., Webb T.R. Comparative pulmonary toxicity assessment of single-wall carbon nanotubes in rats. Toxicol. Sci. 2004, 77:117-125.
51. Warheit D.B. How meaningful are the results of nanotoxicity studies in the absence of adequate material characterization?. Toxicol. Sci. 2008, 101:183-185.
52. Williams G.T., Williams W.J. Granulomatous inflammation-a review. J. Clin. Pathol. 1983, 36:723-733.