Intratracheal instillation of single-wall carbon nanotubes in the rat lung induces time-dependent changes in gene expression

Nanotoxicology

Volumn 9, Issue 3, 2015, Pages 290-301

  Fujita, Katsuhide ^a,b   Fukuda, Makiko ^b   Fukui, Hiroko ^a   Horie, Masanori ^c   Endoh, Shigehisa ^b   Uchida, Kunio ^a   Shichiri, Mototada ^a   Morimoto, Yasuo ^c   Ogami, Akira ^c   Iwahashi, Hitoshi ^d  

^a NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

^b Technology Research Association for Single Wall Carbon Nanotubes   (Japan)

^c UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

^d GIFU UNIVERSITY   (Japan)

Author keywords

Fiber toxicology; Genomics; Nanotoxicology; Nanotubes

Indexed keywords

BIOLOGICAL MARKER; CATHEPSIN K; GLUCAGON RECEPTOR; GLYCOPROTEIN; H TRANSPORTING ATPASE LYSOSOMAL V0 SUBUNIT D2; LACTOPEROXIDASE; LEUKOCYTE IMMUNOGLOBULIN LIKE RECEPTOR SUBFAMILY B MEMBER 4; MACROPHAGE ELASTASE; MACROPHAGE RECEPTOR WITH COLLAGENOUS STRUCTURE; MATRILYSIN; MELANOREGULIN; OSTEOPONTIN; OX40 LIGAND; PENDRIN; PEPTIDYL ARGININE DEIMINASE TYPE I; RIBONUCLEASE RNASE A FAMILY 9; SINGLE WALLED NANOTUBE; TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELL 2; UNCLASSIFIED DRUG; CARBON NANOTUBE; SPP1 PROTEIN, RAT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY WEIGHT; CELL PROLIFERATION; CHEMOTAXIS; CONTROLLED STUDY; DOSE RESPONSE; GENE EXPRESSION PROFILING; HISTOPATHOLOGY; IMMUNE SYSTEM; IMMUNOHISTOCHEMISTRY; INFLAMMATION; LEUKOCYTE MIGRATION; LUNG ALVEOLUS MACROPHAGE; LUNG GRANULOMA; LUNG TOXICITY; LUNG WEIGHT; MALE; MICROARRAY ANALYSIS; NONHUMAN; PRIORITY JOURNAL; RAT; UPREGULATION; ANIMAL; DRUG ADMINISTRATION ROUTE; DRUG EFFECTS; ENZYMOLOGY; GENE EXPRESSION; LUNG; METABOLISM; ORGAN SIZE; TRACHEA;

RATTUS;

ANIMALS; BODY WEIGHT; DRUG ADMINISTRATION ROUTES; GENE EXPRESSION; LUNG; MATRIX METALLOPROTEINASE 12; MATRIX METALLOPROTEINASE 7; NANOTUBES, CARBON; ORGAN SIZE; OSTEOPONTIN; RATS; TRACHEA;

EID: 84929670850     PISSN: 17435390     EISSN: 17435404     Source Type: Journal    
DOI: 10.3109/17435390.2014.921737     Document Type: Article

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