Pulmonary toxicity of multi-walled carbon nanotubes (Baytubes®) relative to α-quartz following a single 6 h inhalation exposure of rats and a 3 months post-exposure period

Toxicology

Volumn 266, Issue 1-3, 2009, Pages 16-29

  Ellinger Ziegelbauer, Heidrun ^a   Pauluhn, Jürgen ^a  

^a BAYER PHARMA AG   (Germany)

Author keywords

Clearance; Disposition; Extrapulmonary toxicity; Gene deregulation; Inhalation testing; Lung remodeling; Metal impurities; Multi walled carbon nanotubes; Translocation

Indexed keywords

COLLAGEN; METAL; MULTI WALLED NANOTUBE; SILICON DIOXIDE;

AEROSOL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHEMICAL STRUCTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; EXPOSURE; EXTRACELLULAR MATRIX; HISTOPATHOLOGY; INHALATION; LUNG DEPOSIT; LUNG HOMOGENATE; LUNG LAVAGE; LUNG PARENCHYMA; LUNG TOXICITY; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PARTICLE SIZE; PNEUMONIA; PRIORITY JOURNAL; RAT; TRANSCRIPTOMICS; WISTAR RAT;

AEROSOLS; AIRWAY REMODELING; ANIMALS; BRONCHOALVEOLAR LAVAGE FLUID; CLUSTER ANALYSIS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENVIRONMENTAL POLLUTANTS; EXTRACELLULAR MATRIX; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; INHALATION EXPOSURE; LUNG; MALE; MOLECULAR STRUCTURE; NANOTUBES, CARBON; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; ORGAN SIZE; PNEUMONIA; QUARTZ; RATS; RATS, WISTAR; TIME FACTORS; TISSUE DISTRIBUTION;

RATTUS; RATTUS NORVEGICUS;

EID: 70449674076     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2009.10.007     Document Type: Article

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