-
1
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan, D. et al. (2000) The hallmarks of cancer. Cell, 100, 57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
-
2
-
-
79952284127
-
Hallmarks of cancer
-
Hanahan, D. et al. (2011) Hallmarks of cancer. Cell, 144, 646-674.
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
-
3
-
-
84911465724
-
How to make a cardiomyocyte
-
Später, D. et al. (2014) How to make a cardiomyocyte. Development, 141, 4418-4431.
-
(2014)
Development
, vol.141
, pp. 4418-4431
-
-
Später, D.1
-
4
-
-
0004152743
-
The Biology of Cell Reproduction
-
Harvard University Press, Boston, MA.
-
Baserga, R. (1985) The Biology of Cell Reproduction. Harvard University Press, Boston, MA.
-
(1985)
-
-
Baserga, R.1
-
5
-
-
0026504147
-
Social controls on cell survival and cell death
-
Raff, M.C. (1992) Social controls on cell survival and cell death. Nature, 356, 397-400.
-
(1992)
Nature
, vol.356
, pp. 397-400
-
-
Raff, M.C.1
-
6
-
-
78049248432
-
Allele specific copy number analysis of tumours
-
van Loo, P. et al. (2010) Allele specific copy number analysis of tumours. Proc. Natl Acad. Sci. USA, 107, 16910-16915.
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 16910-16915
-
-
van Loo, P.1
-
7
-
-
77955603605
-
Genomic architecture characterizes tumor progression paths and fate in breast cancer patients
-
Russnes, H.G. et al. (2010) Genomic architecture characterizes tumor progression paths and fate in breast cancer patients. Sci. Transl. Med., 2, 38ra47.
-
(2010)
Sci. Transl. Med
, vol.2
, pp. 38ra47
-
-
Russnes, H.G.1
-
8
-
-
0022482982
-
In vitro thymidine labelling index in primary operable breast cancer
-
Holt, S. et al. (1986) In vitro thymidine labelling index in primary operable breast cancer. Eur. J. Surg. Oncol., 12, 53-57.
-
(1986)
Eur. J. Surg. Oncol.
, vol.12
, pp. 53-57
-
-
Holt, S.1
-
9
-
-
0026072872
-
Pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: experience from a large study with long-term follow-up
-
Elston, C.W. et al. (1991) Pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: experience from a large study with long-term follow-up. Histopathology, 19, 403-410.
-
(1991)
Histopathology
, vol.19
, pp. 403-410
-
-
Elston, C.W.1
-
10
-
-
0004241834
-
The Biology of the Cell Cycle
-
Cambridge University Press, Cambridge, UK.
-
Mitchison, J.M. (1971) The Biology of the Cell Cycle. Cambridge University Press, Cambridge, UK.
-
(1971)
-
-
Mitchison, J.M.1
-
11
-
-
0013804419
-
Quantitative cytophotometric and autoradiographic studies on the rate of protein synthesis during interphase in mouse fibroblasts in vitro
-
Zetterberg, A. et al. (1965) Quantitative cytophotometric and autoradiographic studies on the rate of protein synthesis during interphase in mouse fibroblasts in vitro. Exp. Cell Res., 40, 1-11.
-
(1965)
Exp. Cell Res.
, vol.40
, pp. 1-11
-
-
Zetterberg, A.1
-
12
-
-
0001256901
-
Synthesis of nucleoprotein in bean root cells
-
Howard, A. et al. (1951) Synthesis of nucleoprotein in bean root cells. Nature, 167, 599-600.
-
(1951)
Nature
, vol.167
, pp. 599-600
-
-
Howard, A.1
-
13
-
-
0003418645
-
A restriction point for control of normal animal cell proliferation
-
Pardee, A.B. (1974) A restriction point for control of normal animal cell proliferation. Proc. Natl Acad. Sci. USA, 71, 1286-1290.
-
(1974)
Proc. Natl Acad. Sci. USA
, vol.71
, pp. 1286-1290
-
-
Pardee, A.B.1
-
14
-
-
0026387912
-
Coordination between cell growth and cell cycle transit in animal cells
-
Zetterberg, A. et al. (1991) Coordination between cell growth and cell cycle transit in animal cells. Cold Spring Harb. Symp. Quant. Biol., 56, 137-147.
-
(1991)
Cold Spring Harb. Symp. Quant. Biol.
, vol.56
, pp. 137-147
-
-
Zetterberg, A.1
-
15
-
-
0021893250
-
Cell-cycle-specific induction of quiescence achieved by limited inhibition of protein synthesis: counteractive effect of addition of purified growth factors
-
Larsson, O. et al. (1985) Cell-cycle-specific induction of quiescence achieved by limited inhibition of protein synthesis: counteractive effect of addition of purified growth factors. J. Cell Sci., 73, 375-387.
-
(1985)
J. Cell Sci.
, vol.73
, pp. 375-387
-
-
Larsson, O.1
-
16
-
-
0022042266
-
Consequences of parental exposure to serumfree medium for progeny cell division
-
Larsson, O. et al. (1985) Consequences of parental exposure to serumfree medium for progeny cell division. J. Cell Sci., 75, 259-268.
-
(1985)
J. Cell Sci.
, vol.75
, pp. 259-268
-
-
Larsson, O.1
-
17
-
-
0022495396
-
Immediate effects of serum depletion on dissociation between growth in size and cell division in proliferating 3T3 cells
-
Larsson, O. et al. (1986) Immediate effects of serum depletion on dissociation between growth in size and cell division in proliferating 3T3 cells. J. Cell. Physiol., 127, 267-273.
-
(1986)
J. Cell. Physiol.
, vol.127
, pp. 267-273
-
-
Larsson, O.1
-
18
-
-
0033614998
-
Creation of human tumour cells with defined genetic elements
-
Hahn, W.C. et al. (1999) Creation of human tumour cells with defined genetic elements. Nature, 400, 464-468.
-
(1999)
Nature
, vol.400
, pp. 464-468
-
-
Hahn, W.C.1
-
19
-
-
41549090369
-
Multiple pathways regulated by the tumor suppressor PP2A in transformation
-
Westermarck, J. et al. (2008) Multiple pathways regulated by the tumor suppressor PP2A in transformation. Trends Mol. Med., 14, 152-160.
-
(2008)
Trends Mol. Med.
, vol.14
, pp. 152-160
-
-
Westermarck, J.1
-
20
-
-
3943107573
-
Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints
-
Sancar, A. et al. (2004) Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints. Annu. Rev. Biochem., 73, 39-85.
-
(2004)
Annu. Rev. Biochem.
, vol.73
, pp. 39-85
-
-
Sancar, A.1
-
21
-
-
0001510491
-
The RB and p53 pathways in cancer
-
Sherr, C.J. et al. (2002) The RB and p53 pathways in cancer. Cancer Cell, 2, 103-112.
-
(2002)
Cancer Cell
, vol.2
, pp. 103-112
-
-
Sherr, C.J.1
-
22
-
-
0034671578
-
TGF-beta inhibits p70 S6 kinase via protein phosphatase 2A to induce G(1) arrest
-
Petritsch, C. et al. (2000) TGF-beta inhibits p70 S6 kinase via protein phosphatase 2A to induce G(1) arrest. Genes Dev., 14, 3093-3101.
-
(2000)
Genes Dev.
, vol.14
, pp. 3093-3101
-
-
Petritsch, C.1
-
23
-
-
22544450728
-
Transformation of human and murine fibroblasts without viral oncoproteins
-
Boehm, J.S. et al. (2005) Transformation of human and murine fibroblasts without viral oncoproteins. Mol. Cell. Biol., 25, 6464-6474.
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 6464-6474
-
-
Boehm, J.S.1
-
24
-
-
0033618410
-
Multiple ras effector pathways contribute to G(1) cell cycle progression
-
Gille, H. et al. (1999) Multiple ras effector pathways contribute to G(1) cell cycle progression. J. Biol. Chem., 274, 22033-22040.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 22033-22040
-
-
Gille, H.1
-
25
-
-
0032541671
-
Cell cycle targets of Ras/Raf signalling
-
Kerkhoff, E. et al. (1998) Cell cycle targets of Ras/Raf signalling. Oncogene, 17, 1457-1462.
-
(1998)
Oncogene
, vol.17
, pp. 1457-1462
-
-
Kerkhoff, E.1
-
26
-
-
51849111556
-
PI3K pathway alterations in cancer: variations on a theme
-
Yuan, T.L. et al. (2008) PI3K pathway alterations in cancer: variations on a theme. Oncogene, 27, 5497-5510.
-
(2008)
Oncogene
, vol.27
, pp. 5497-5510
-
-
Yuan, T.L.1
-
27
-
-
34250788809
-
AKT/PKB signaling: navigating downstream
-
Manning, B.D. et al. (2007) AKT/PKB signaling: navigating downstream. Cell, 129, 1261-1274.
-
(2007)
Cell
, vol.129
, pp. 1261-1274
-
-
Manning, B.D.1
-
28
-
-
44449161481
-
The TSC1-TSC2 complex: a molecular switchboard controlling cell growth
-
Huang, J. et al. (2008) The TSC1-TSC2 complex: a molecular switchboard controlling cell growth. Biochem. J., 412, 179-190.
-
(2008)
Biochem. J.
, vol.412
, pp. 179-190
-
-
Huang, J.1
-
29
-
-
46149098447
-
Phospholipase D1 is an effector of Rheb in the mTOR pathway
-
Sun, Y. et al. (2008) Phospholipase D1 is an effector of Rheb in the mTOR pathway. Proc. Natl Acad. Sci. USA, 105, 8286-8291.
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 8286-8291
-
-
Sun, Y.1
-
30
-
-
62849111751
-
Regulation of mTORC1 and mTORC2 complex assembly by phosphatidic acid: competition with rapamycin
-
Toschi, A. et al. (2009) Regulation of mTORC1 and mTORC2 complex assembly by phosphatidic acid: competition with rapamycin. Mol. Cell. Biol., 29, 1411-1420.
-
(2009)
Mol. Cell. Biol.
, vol.29
, pp. 1411-1420
-
-
Toschi, A.1
-
31
-
-
68949103681
-
Phosphatidic acid signaling to mTOR: signals for the survival of human cancer cells
-
Foster, D.A. (2009) Phosphatidic acid signaling to mTOR: signals for the survival of human cancer cells. Biochim. Biophys. Acta, 1791, 949-955.
-
(2009)
Biochim. Biophys. Acta
, vol.1791
, pp. 949-955
-
-
Foster, D.A.1
-
32
-
-
34347220473
-
Defining the role of mTOR in cancer
-
Guertin, D.A. et al. (2007) Defining the role of mTOR in cancer. Cancer Cell, 12, 9-22.
-
(2007)
Cancer Cell
, vol.12
, pp. 9-22
-
-
Guertin, D.A.1
-
33
-
-
0034948814
-
Differential regulation of retinoblastoma tumor suppressor protein by G(1) cyclin-dependent kinase complexes in vivo
-
Ezhevsky, S.A. et al. (2001) Differential regulation of retinoblastoma tumor suppressor protein by G(1) cyclin-dependent kinase complexes in vivo. Mol. Cell. Biol., 21, 4773-4784.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 4773-4784
-
-
Ezhevsky, S.A.1
-
34
-
-
0033578816
-
Cdk phosphorylation triggers sequential intramolecular interactions that progressively block Rb functions as cells move through G1
-
Harbour, J.W. et al. (1999) Cdk phosphorylation triggers sequential intramolecular interactions that progressively block Rb functions as cells move through G1. Cell, 98, 859-869.
-
(1999)
Cell
, vol.98
, pp. 859-869
-
-
Harbour, J.W.1
-
35
-
-
77950882445
-
pRb and control of the cell cycle clock
-
New York, NY
-
Weinberg, R.A. (2007) pRb and control of the cell cycle clock. In The Biology of Cancer. Garland Science, New York, NY, pp. 255-307.
-
(2007)
The Biology of Cancer. Garland Science
, pp. 255-307
-
-
Weinberg, R.A.1
-
36
-
-
0035052628
-
Accumulation of cyclin E is not a prerequisite for passage through the restriction point
-
Ekholm, S.V. et al. (2001) Accumulation of cyclin E is not a prerequisite for passage through the restriction point. Mol. Cell. Biol., 21, 3256-3263.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 3256-3263
-
-
Ekholm, S.V.1
-
37
-
-
16244362678
-
Single cell analysis of G1 check points- the relationship between the restriction point and phosphorylation of pRb
-
Martinsson, H.S. et al. (2005) Single cell analysis of G1 check points- the relationship between the restriction point and phosphorylation of pRb. Exp. Cell Res., 305, 383-391.
-
(2005)
Exp. Cell Res.
, vol.305
, pp. 383-391
-
-
Martinsson, H.S.1
-
38
-
-
0036467506
-
Regulation of G(1) cell-cycle progression by oncogenes and tumor suppressor genes
-
Ho, A. et al. (2002) Regulation of G(1) cell-cycle progression by oncogenes and tumor suppressor genes. Curr. Opin. Genet. Dev., 12, 47-52.
-
(2002)
Curr. Opin. Genet. Dev.
, vol.12
, pp. 47-52
-
-
Ho, A.1
-
39
-
-
9244239811
-
G1 cell-cycle control and cancer
-
Massagué, J. (2004) G1 cell-cycle control and cancer. Nature, 432, 298-306.
-
(2004)
Nature
, vol.432
, pp. 298-306
-
-
Massagué, J.1
-
40
-
-
0034469509
-
Transforming growth factor-β and breast cancer:cell cycle arrest by transforming growth factor-β and its disruption in cancer
-
Donovan, J. et al. (2000) Transforming growth factor-β and breast cancer:cell cycle arrest by transforming growth factor-β and its disruption in cancer. Breast Cancer Res., 2, 116-124.
-
(2000)
Breast Cancer Res.
, vol.2
, pp. 116-124
-
-
Donovan, J.1
-
41
-
-
0022368305
-
Specific growth response of ras-transformed embryo fibroblasts to tumour promoters
-
Dotto, G.P. et al. (1985) Specific growth response of ras-transformed embryo fibroblasts to tumour promoters. Nature, 318, 472-475.
-
(1985)
Nature
, vol.318
, pp. 472-475
-
-
Dotto, G.P.1
-
42
-
-
0030987327
-
Tumor promotion by depleting cells of protein kinase C delta
-
Lu, Z. et al. (1997) Tumor promotion by depleting cells of protein kinase C delta. Mol. Cell. Biol., 17, 3418-3428.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 3418-3428
-
-
Lu, Z.1
-
43
-
-
0031907117
-
Activation of protein kinase C triggers its ubiquitination and degradation
-
Lu, Z. et al. (1998) Activation of protein kinase C triggers its ubiquitination and degradation. Mol. Cell. Biol., 18, 839-845.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 839-845
-
-
Lu, Z.1
-
44
-
-
0019496277
-
Glutamine and the regulation of DNA replication and cell multiplication in fibroblasts
-
Zetterberg, A. et al. (1981) Glutamine and the regulation of DNA replication and cell multiplication in fibroblasts. J. Cell. Physiol., 108, 365-373.
-
(1981)
J. Cell. Physiol.
, vol.108
, pp. 365-373
-
-
Zetterberg, A.1
-
45
-
-
0028845640
-
What is the restriction point? Curr
-
Zetterberg, A. et al. (1995) What is the restriction point? Curr. Opin. Cell Biol., 7, 835-842.
-
(1995)
Opin. Cell Biol.
, vol.7
, pp. 835-842
-
-
Zetterberg, A.1
-
46
-
-
0343576503
-
Dual control of cell growth by somatomedins and platelet-derived growth factor
-
Stiles, C.D. et al. (1979) Dual control of cell growth by somatomedins and platelet-derived growth factor. Proc. Natl Acad. Sci. USA, 76, 1279-1283.
-
(1979)
Proc. Natl Acad. Sci. USA
, vol.76
, pp. 1279-1283
-
-
Stiles, C.D.1
-
47
-
-
79952111161
-
PI3 kinase regulation of skeletal muscle hypertrophy and atrophy
-
Glass, D.J. (2010) PI3 kinase regulation of skeletal muscle hypertrophy and atrophy. Curr. Top. Microbiol. Immunol., 346, 267-278.
-
(2010)
Curr. Top. Microbiol. Immunol.
, vol.346
, pp. 267-278
-
-
Glass, D.J.1
-
48
-
-
42949139481
-
AMPK phosphorylation of raptor mediates a metabolic checkpoint
-
Gwinn, D.M. et al. (2008) AMPK phosphorylation of raptor mediates a metabolic checkpoint. Mol. Cell, 30, 214-226.
-
(2008)
Mol. Cell
, vol.30
, pp. 214-226
-
-
Gwinn, D.M.1
-
49
-
-
79960048104
-
Regulation of G1 cell cycle progression
-
Foster, D.A. et al. (2010) Regulation of G1 cell cycle progression. Genes Cancer, 1, 1124-1131.
-
(2010)
Genes Cancer
, vol.1
, pp. 1124-1131
-
-
Foster, D.A.1
-
50
-
-
0842348917
-
During human melanoma progression AP-1 binding pairs are altered with loss of c-Jun in vitro
-
Yang, S. et al. (2004) During human melanoma progression AP-1 binding pairs are altered with loss of c-Jun in vitro. Pigment Cell Res., 17, 74-83.
-
(2004)
Pigment Cell Res.
, vol.17
, pp. 74-83
-
-
Yang, S.1
-
51
-
-
84893374012
-
Targeting of magnolin on ERKs inhibits Ras/ERKs/ RSK2-signaling-mediated neoplastic cell transformation
-
Lee, C.J. et al. (2014) Targeting of magnolin on ERKs inhibits Ras/ERKs/ RSK2-signaling-mediated neoplastic cell transformation. Carcinogenesis, 35, 432-441.
-
(2014)
Carcinogenesis
, vol.35
, pp. 432-441
-
-
Lee, C.J.1
-
52
-
-
44449127592
-
The epidermal growth factor receptor family:biology driving targeted therapeutics
-
Wieduwilt, M.J. et al. (2008) The epidermal growth factor receptor family:biology driving targeted therapeutics. Cell. Mol. Life Sci., 65, 1566-1584.
-
(2008)
Cell. Mol. Life Sci.
, vol.65
, pp. 1566-1584
-
-
Wieduwilt, M.J.1
-
53
-
-
34347393724
-
Therapies directed against epidermal growth factor receptor in aerodigestive carcinomas
-
Karamouzis, M.V. et al. (2007) Therapies directed against epidermal growth factor receptor in aerodigestive carcinomas. JAMA, 298, 70-82.
-
(2007)
JAMA
, vol.298
, pp. 70-82
-
-
Karamouzis, M.V.1
-
54
-
-
77954759289
-
Nuclear trafficking of the epidermal growth factor receptor family membrane proteins
-
Wang, Y.N. et al. (2010) Nuclear trafficking of the epidermal growth factor receptor family membrane proteins. Oncogene, 29, 3997-4006.
-
(2010)
Oncogene
, vol.29
, pp. 3997-4006
-
-
Wang, Y.N.1
-
55
-
-
0034855942
-
Nuclear localization of EGF receptor and its potential new role as a transcription factor
-
Lin, S.Y. et al. (2001) Nuclear localization of EGF receptor and its potential new role as a transcription factor. Nat. Cell Biol., 3, 802-808.
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. 802-808
-
-
Lin, S.Y.1
-
56
-
-
33845359095
-
ErbB receptor dimerization, localization, and co-localization in mouse lung type II epithelial cells
-
Zscheppang, K. et al. (2006) ErbB receptor dimerization, localization, and co-localization in mouse lung type II epithelial cells. Pediatr. Pulmonol., 41, 1205-1212.
-
(2006)
Pediatr. Pulmonol.
, vol.41
, pp. 1205-1212
-
-
Zscheppang, K.1
-
57
-
-
84937717523
-
Tackling the cancer signal transduction "Labyrinth": a combinatorial use of biochemical tools with mathematical models will enhance the identification of optimal targets for each molecular defect
-
Karamouzis, M.C. et al. (2014) Tackling the cancer signal transduction "Labyrinth": a combinatorial use of biochemical tools with mathematical models will enhance the identification of optimal targets for each molecular defect. Tum Biol., 35, 5993-6002.
-
(2014)
Tum Biol.
, vol.35
, pp. 5993-6002
-
-
Karamouzis, M.C.1
-
58
-
-
0003986333
-
Nuclear Hormone Receptors: Molecular Mechanisms, Cellular Functions, Clinical Abnormalities
-
Academic Press, London, UK
-
Parker, M.G. (1991) Nuclear Hormone Receptors: Molecular Mechanisms, Cellular Functions, Clinical Abnormalities. Academic Press, London, UK, pp. 1-404.
-
(1991)
, pp. 1-404
-
-
Parker, M.G.1
-
59
-
-
84892495900
-
Dynamic structures of nuclear hormone receptors: new promises and challenges
-
Simons, S.S. et al. (2014) Dynamic structures of nuclear hormone receptors: new promises and challenges. Mol. Endocrinol., 28, 173-182.
-
(2014)
Mol. Endocrinol.
, vol.28
, pp. 173-182
-
-
Simons, S.S.1
-
60
-
-
0023250526
-
Activated oestrogen receptor in human breast cancer: clinical and biochemical correlates
-
White, J.O. et al. (1987) Activated oestrogen receptor in human breast cancer: clinical and biochemical correlates. Br. J. Surg., 74, 588-590.
-
(1987)
Br. J. Surg.
, vol.74
, pp. 588-590
-
-
White, J.O.1
-
61
-
-
0030579801
-
Cloning of a novel receptor expressed in rat prostate and ovary
-
Kuiper, G.G. et al. (1996) Cloning of a novel receptor expressed in rat prostate and ovary. Proc. Natl Acad. Sci. USA, 93, 5925-5930.
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, pp. 5925-5930
-
-
Kuiper, G.G.1
-
62
-
-
0033305431
-
The estrogen receptor enhances AP-1 activity by two distinct mechanisms with different requirements for receptor transactivation functions
-
Webb, P. et al. (1999) The estrogen receptor enhances AP-1 activity by two distinct mechanisms with different requirements for receptor transactivation functions. Mol. Endocrinol., 13, 1672-1685.
-
(1999)
Mol. Endocrinol.
, vol.13
, pp. 1672-1685
-
-
Webb, P.1
-
63
-
-
0035228654
-
Transcriptional activation of genes by 17 beta-estradiol through estrogen receptor-Sp1 interactions
-
Safe, S. (2001) Transcriptional activation of genes by 17 beta-estradiol through estrogen receptor-Sp1 interactions. Vitam. Horm., 62, 231-252.
-
(2001)
Vitam. Horm.
, vol.62
, pp. 231-252
-
-
Safe, S.1
-
64
-
-
8344275588
-
The biological role of estrogen receptors alpha and beta in cancer
-
Pearce, S.T. et al. (2004) The biological role of estrogen receptors alpha and beta in cancer. Crit. Rev. Oncol. Hematol., 50, 3-22.
-
(2004)
Crit. Rev. Oncol. Hematol.
, vol.50
, pp. 3-22
-
-
Pearce, S.T.1
-
65
-
-
33747466839
-
Structure-function relationship of estrogen receptor alpha and beta: impact on human health
-
Ascenzi, P. et al. (2006) Structure-function relationship of estrogen receptor alpha and beta: impact on human health. Mol. Aspects Med., 27, 299-402.
-
(2006)
Mol. Aspects Med.
, vol.27
, pp. 299-402
-
-
Ascenzi, P.1
-
66
-
-
33846066888
-
Estrogen signaling multiple pathways to impact gene transcription
-
Marino, M. et al. (2006) Estrogen signaling multiple pathways to impact gene transcription. Curr. Genom., 7, 497-508.
-
(2006)
Curr. Genom.
, vol.7
, pp. 497-508
-
-
Marino, M.1
-
67
-
-
29844458399
-
Estrogen receptor beta, a possible tumor suppressor involved in ovarian carcinogenesis
-
Lazennec, G. (2006) Estrogen receptor beta, a possible tumor suppressor involved in ovarian carcinogenesis. Cancer Lett., 231, 151-157.
-
(2006)
Cancer Lett.
, vol.231
, pp. 151-157
-
-
Lazennec, G.1
-
68
-
-
79960948311
-
Novel approaches to quantify estradiolinduced loss of ERβ1 protein in older mouse ovarian surface epithelium:new tools to assess the role of ER protein subtypes in predisposing to ovarian epithelial cancer? Horm
-
Gulliver, L.S. et al. (2011) Novel approaches to quantify estradiolinduced loss of ERβ1 protein in older mouse ovarian surface epithelium:new tools to assess the role of ER protein subtypes in predisposing to ovarian epithelial cancer? Horm. Cancer, 2, 204-213.
-
(2011)
Cancer
, vol.2
, pp. 204-213
-
-
Gulliver, L.S.1
-
69
-
-
4944246588
-
Loss of ERbeta expression as a common step in estrogen-dependent tumor progression
-
Bardin, A. et al. (2004) Loss of ERbeta expression as a common step in estrogen-dependent tumor progression. Endocr. Relat. Cancer, 11, 537-551.
-
(2004)
Endocr. Relat. Cancer
, vol.11
, pp. 537-551
-
-
Bardin, A.1
-
70
-
-
84866132321
-
Potential role of estrogen receptor beta as a tumor suppressor of epithelial ovarian cancer
-
Bossard, C. et al. (2012) Potential role of estrogen receptor beta as a tumor suppressor of epithelial ovarian cancer. PLoS One, 7, e44787.
-
(2012)
PLoS One
, vol.7
, pp. e44787
-
-
Bossard, C.1
-
71
-
-
1642535535
-
Estrogen receptor beta inhibits human breast cancer cell proliferation and tumor formation by causing a G2 cell cycle arrest
-
Paruthiyil, S. et al. (2004) Estrogen receptor beta inhibits human breast cancer cell proliferation and tumor formation by causing a G2 cell cycle arrest. Cancer Res., 64, 423-428.
-
(2004)
Cancer Res.
, vol.64
, pp. 423-428
-
-
Paruthiyil, S.1
-
72
-
-
4344707522
-
Steroid receptors and cell cycle in normal mammary epithelium
-
Anderson, E. et al. (2004) Steroid receptors and cell cycle in normal mammary epithelium. J. Mammary Gland Biol. Neoplasia, 9, 3-13.
-
(2004)
J. Mammary Gland Biol. Neoplasia
, vol.9
, pp. 3-13
-
-
Anderson, E.1
-
73
-
-
33748084024
-
Development of a mouse model of mammary gland versus uterus tissue selectivity using estrogen- and progesterone- regulated gene markers
-
Crabtree, J.S. et al. (2006) Development of a mouse model of mammary gland versus uterus tissue selectivity using estrogen- and progesterone- regulated gene markers. J. Steroid Biochem. Mol. Biol., 101, 11-21.
-
(2006)
J. Steroid Biochem. Mol. Biol.
, vol.101
, pp. 11-21
-
-
Crabtree, J.S.1
-
74
-
-
48249132499
-
Signal transducer and activator of transcription 5b, c-Src, and epidermal growth factor receptor signaling play integral roles in estrogen-stimulated proliferation of estrogen receptor-positive breast cancer cells
-
Fox, E.M. et al. (2008) Signal transducer and activator of transcription 5b, c-Src, and epidermal growth factor receptor signaling play integral roles in estrogen-stimulated proliferation of estrogen receptor-positive breast cancer cells. Mol. Endocrinol., 22, 1781-1796.
-
(2008)
Mol. Endocrinol.
, vol.22
, pp. 1781-1796
-
-
Fox, E.M.1
-
75
-
-
1642329884
-
S-palmitoylation modulates human estrogen receptor-alpha functions
-
Acconcia, F. et al. (2004) S-palmitoylation modulates human estrogen receptor-alpha functions. Biochem. Biophys. Res. Commun., 316, 878-883.
-
(2004)
Biochem. Biophys. Res. Commun.
, vol.316
, pp. 878-883
-
-
Acconcia, F.1
-
76
-
-
84883645377
-
Estradiol and tamoxifen induce cell migration through GPR30 and activation of focal adhesion kinase (FAK) in endometrial cancers with low or without nuclear estrogen receptor α (ERα)
-
Tsai, C.L. et al. (2013) Estradiol and tamoxifen induce cell migration through GPR30 and activation of focal adhesion kinase (FAK) in endometrial cancers with low or without nuclear estrogen receptor α (ERα). PLoS One, 8, e72999.
-
(2013)
PLoS One
, vol.8
, pp. e72999
-
-
Tsai, C.L.1
-
77
-
-
84895783781
-
Beta-naphthoflavone (DB06732) mediates estrogen receptor-positive breast cancer cell cycle arrest through AhR-dependent regulation of PI3K/AKT and MAPK/ERK signaling
-
Wang, C. et al. (2014) Beta-naphthoflavone (DB06732) mediates estrogen receptor-positive breast cancer cell cycle arrest through AhR-dependent regulation of PI3K/AKT and MAPK/ERK signaling. Carcinogenesis., 35, 703-713.
-
(2014)
Carcinogenesis.
, vol.35
, pp. 703-713
-
-
Wang, C.1
-
78
-
-
84861610903
-
Regulation of HRG-β1-induced proliferation, migration and invasion of MCF-7 cells by upregulation of GPR30 expression
-
Ruan, S.Q. et al. (2012) Regulation of HRG-β1-induced proliferation, migration and invasion of MCF-7 cells by upregulation of GPR30 expression. Mol. Med. Rep., 6, 131-138.
-
(2012)
Mol. Med. Rep.
, vol.6
, pp. 131-138
-
-
Ruan, S.Q.1
-
79
-
-
84879713811
-
Protein tyrosine phosphatases as novel targets in breast cancer therapy
-
Nunes-Xavier, C.E. et al. (2013) Protein tyrosine phosphatases as novel targets in breast cancer therapy. Biochim. Biophys. Acta, 1836, 211-226.
-
(2013)
Biochim. Biophys. Acta
, vol.1836
, pp. 211-226
-
-
Nunes-Xavier, C.E.1
-
80
-
-
0036794395
-
Signal transducers and activators of transcription as downstream targets of nongenomic estrogen receptor actions
-
Björnström, L. et al. (2002) Signal transducers and activators of transcription as downstream targets of nongenomic estrogen receptor actions. Mol. Endocrinol., 16, 2202-2214.
-
(2002)
Mol. Endocrinol.
, vol.16
, pp. 2202-2214
-
-
Björnström, L.1
-
81
-
-
67749113293
-
The role of miR-206 in the epidermal growth factor (EGF) induced repression of estrogen receptor-alpha (ERalpha) signaling and a luminal phenotype in MCF-7 breast cancer cells
-
Adams, B.D. et al. (2009) The role of miR-206 in the epidermal growth factor (EGF) induced repression of estrogen receptor-alpha (ERalpha) signaling and a luminal phenotype in MCF-7 breast cancer cells. Mol. Endocrinol., 23, 1215-1230.
-
(2009)
Mol. Endocrinol.
, vol.23
, pp. 1215-1230
-
-
Adams, B.D.1
-
82
-
-
0036188807
-
Changes in proinflammatory cytokine activity after menopause
-
Pfeilschifter, J. et al. (2002) Changes in proinflammatory cytokine activity after menopause. Endocr. Rev., 23, 90-119.
-
(2002)
Endocr. Rev.
, vol.23
, pp. 90-119
-
-
Pfeilschifter, J.1
-
83
-
-
0024307106
-
Interleukin-1 induced T-lymphocyte proliferation and its relation to IL-1 receptors
-
Dinarello, C.A. et al. (1989) Interleukin-1 induced T-lymphocyte proliferation and its relation to IL-1 receptors. Adv. Exp. Med. Biol., 254, 45-53.
-
(1989)
Adv. Exp. Med. Biol.
, vol.254
, pp. 45-53
-
-
Dinarello, C.A.1
-
84
-
-
0034268386
-
Interleukin-18, a proinflammatory cytokine
-
Dinarello, C.A. (2000) Interleukin-18, a proinflammatory cytokine. Eur. Cytokine Netw., 11, 483-486.
-
(2000)
Eur. Cytokine Netw.
, vol.11
, pp. 483-486
-
-
Dinarello, C.A.1
-
85
-
-
0035804254
-
ICOS co-stimulatory receptor is essential for T-cell activation and function
-
Dong, C. et al. (2001) ICOS co-stimulatory receptor is essential for T-cell activation and function. Nature, 409, 97-101.
-
(2001)
Nature
, vol.409
, pp. 97-101
-
-
Dong, C.1
-
86
-
-
56349169914
-
Alternative lifestyles of T cells
-
Tato, C.M. et al. (2008) Alternative lifestyles of T cells. Nat. Immunol., 9, 1323-1325.
-
(2008)
Nat. Immunol.
, vol.9
, pp. 1323-1325
-
-
Tato, C.M.1
-
87
-
-
84888393766
-
Autocrine production of interleukin-6 confers ovarian cancer cells resistance to tamoxifen via ER isoforms and SRC-1
-
Wang, Y. et al. (2014) Autocrine production of interleukin-6 confers ovarian cancer cells resistance to tamoxifen via ER isoforms and SRC-1. Mol. Cell. Endocrinol., 382, 791-803.
-
(2014)
Mol. Cell. Endocrinol.
, vol.382
, pp. 791-803
-
-
Wang, Y.1
-
88
-
-
0035849783
-
G1-Cdk activity is required for both proliferation and viability of cytokine-dependent myeloid and erythroid cells
-
Hofmann, J.F. et al. (2001) G1-Cdk activity is required for both proliferation and viability of cytokine-dependent myeloid and erythroid cells. Oncogene, 20, 4198-4208.
-
(2001)
Oncogene
, vol.20
, pp. 4198-4208
-
-
Hofmann, J.F.1
-
89
-
-
66149145906
-
Androgen receptor controls EGFR and ERBB2 gene expression at different levels in prostate cancer cell lines
-
Pignon, J.C. et al. (2009) Androgen receptor controls EGFR and ERBB2 gene expression at different levels in prostate cancer cell lines. Cancer Res., 69, 2941-2949.
-
(2009)
Cancer Res.
, vol.69
, pp. 2941-2949
-
-
Pignon, J.C.1
-
90
-
-
84873041658
-
Androgen up-regulates vascular endothelial growth factor expression in prostate cancer cells via an Sp1 binding site
-
Eisermann, K. et al. (2013) Androgen up-regulates vascular endothelial growth factor expression in prostate cancer cells via an Sp1 binding site. Mol. Cancer, 12, 7.
-
(2013)
Mol. Cancer
, vol.12
, pp. 7
-
-
Eisermann, K.1
-
91
-
-
0028113415
-
Androgen receptor activation in prostatic tumor cell lines by insulin-like growth factor-I, keratinocyte growth factor, and epidermal growth factor
-
Culig, Z. et al. (1994) Androgen receptor activation in prostatic tumor cell lines by insulin-like growth factor-I, keratinocyte growth factor, and epidermal growth factor. Cancer Res., 54, 5474-5478.
-
(1994)
Cancer Res.
, vol.54
, pp. 5474-5478
-
-
Culig, Z.1
-
92
-
-
0034675994
-
Steroid-induced androgen receptor-oestradiol receptor beta-Src complex triggers prostate cancer cell proliferation
-
Migliaccio, A. et al. (2000) Steroid-induced androgen receptor-oestradiol receptor beta-Src complex triggers prostate cancer cell proliferation. EMBO J., 19, 5406-5417.
-
(2000)
EMBO J.
, vol.19
, pp. 5406-5417
-
-
Migliaccio, A.1
-
93
-
-
80052927758
-
Analysis of androgen receptor rapid actions in cellular signaling pathways: receptor/Src association
-
Migliaccio, A. et al. (2011) Analysis of androgen receptor rapid actions in cellular signaling pathways: receptor/Src association. Methods Mol. Biol., 776, 361-370.
-
(2011)
Methods Mol. Biol.
, vol.776
, pp. 361-370
-
-
Migliaccio, A.1
-
94
-
-
0030333504
-
Androgen receptor gene amplification: a novel molecular mechanism for endocrine therapy resistance in human prostate cancer
-
Koivisto, P. et al. (1996) Androgen receptor gene amplification: a novel molecular mechanism for endocrine therapy resistance in human prostate cancer. Scand. J. Clin. Lab. Invest. Suppl., 226, 57-63.
-
(1996)
Scand. J. Clin. Lab. Invest. Suppl.
, vol.226
, pp. 57-63
-
-
Koivisto, P.1
-
95
-
-
0028944138
-
In vivo amplification of the androgen receptor gene and progression of human prostate cancer
-
Visakorpi, T. et al. (1995) In vivo amplification of the androgen receptor gene and progression of human prostate cancer. Nat. Genet., 9, 401-406.
-
(1995)
Nat. Genet.
, vol.9
, pp. 401-406
-
-
Visakorpi, T.1
-
96
-
-
15644368237
-
Androgen receptor gene amplification: a possible molecular mechanism for androgen deprivation therapy failure in prostate cancer
-
Koivisto, P. et al. (1997) Androgen receptor gene amplification: a possible molecular mechanism for androgen deprivation therapy failure in prostate cancer. Cancer Res., 57, 314-319.
-
(1997)
Cancer Res.
, vol.57
, pp. 314-319
-
-
Koivisto, P.1
-
97
-
-
0035328474
-
Amplification and overexpression of androgen receptor gene in hormone-refractory prostate cancer
-
Linja, M.J. et al. (2001) Amplification and overexpression of androgen receptor gene in hormone-refractory prostate cancer. Cancer Res., 61, 3550-3555.
-
(2001)
Cancer Res.
, vol.61
, pp. 3550-3555
-
-
Linja, M.J.1
-
98
-
-
0026562430
-
The androgen receptor in LNCaP cells contains a mutation in the ligand binding domain which affects steroid binding characteristics and response to antiandrogens
-
Veldscholte, J. et al. (1992) The androgen receptor in LNCaP cells contains a mutation in the ligand binding domain which affects steroid binding characteristics and response to antiandrogens. J. Steroid Biochem. Mol. Biol., 41, 665-669.
-
(1992)
J. Steroid Biochem. Mol. Biol.
, vol.41
, pp. 665-669
-
-
Veldscholte, J.1
-
99
-
-
48549089747
-
Splicing of a novel androgen receptor exon generates a constitutively active androgen receptor that mediates prostate cancer therapy resistance
-
Dehm, S.M. et al. (2008) Splicing of a novel androgen receptor exon generates a constitutively active androgen receptor that mediates prostate cancer therapy resistance. Cancer Res., 68, 5469-5477.
-
(2008)
Cancer Res.
, vol.68
, pp. 5469-5477
-
-
Dehm, S.M.1
-
100
-
-
74049109753
-
Identification of novel truncated androgen receptor (AR) mutants including unreported pre-mRNA splicing variants in the 22Rv1 hormone-refractory prostate cancer (PCa) cell line
-
Marcias, G. et al. (2010) Identification of novel truncated androgen receptor (AR) mutants including unreported pre-mRNA splicing variants in the 22Rv1 hormone-refractory prostate cancer (PCa) cell line. Hum. Mutat., 31, 74-80.
-
(2010)
Hum. Mutat.
, vol.31
, pp. 74-80
-
-
Marcias, G.1
-
101
-
-
0037112372
-
Characterization of a novel androgen receptor mutation in a relapsed CWR22 prostate cancer xenograft and cell line
-
Tepper, C.G. et al. (2002) Characterization of a novel androgen receptor mutation in a relapsed CWR22 prostate cancer xenograft and cell line. Cancer Res., 62, 6606-6614.
-
(2002)
Cancer Res.
, vol.62
, pp. 6606-6614
-
-
Tepper, C.G.1
-
102
-
-
84864356765
-
The androgen receptor gene mutations database:2012 update
-
Gottlieb, B. et al. (2012) The androgen receptor gene mutations database:2012 update. Hum. Mutat., 33, 887-894.
-
(2012)
Hum. Mutat.
, vol.33
, pp. 887-894
-
-
Gottlieb, B.1
-
103
-
-
33746047132
-
Pharmacologic basis for the enhanced efficacy of dutasteride against prostatic cancers
-
Xu, Y. et al. (2006) Pharmacologic basis for the enhanced efficacy of dutasteride against prostatic cancers. Clin. Cancer Res., 12, 4072-4079.
-
(2006)
Clin. Cancer Res.
, vol.12
, pp. 4072-4079
-
-
Xu, Y.1
-
104
-
-
6444233171
-
Aromatase inhibitors: a new paradigm in breast cancer treatment
-
Narashimamurthy, J. et al. (2004) Aromatase inhibitors: a new paradigm in breast cancer treatment. Curr. Med. Chem. Anticancer Agents, 4, 523-534.
-
(2004)
Curr. Med. Chem. Anticancer Agents
, vol.4
, pp. 523-534
-
-
Narashimamurthy, J.1
-
105
-
-
33846236919
-
The promoter of the rat 5alpha-reductase type 1 gene is bidirectional and Sp1-dependent
-
Blanchard, Y. et al. (2007) The promoter of the rat 5alpha-reductase type 1 gene is bidirectional and Sp1-dependent. Mol. Cell. Endocrinol., 264, 171-183.
-
(2007)
Mol. Cell. Endocrinol.
, vol.264
, pp. 171-183
-
-
Blanchard, Y.1
-
106
-
-
80051975232
-
Targeting Sp1 transcription factors in prostate cancer therapy
-
Sankpal, U.T. et al. (2011) Targeting Sp1 transcription factors in prostate cancer therapy. Med. Chem., 7, 518-525.
-
(2011)
Med. Chem.
, vol.7
, pp. 518-525
-
-
Sankpal, U.T.1
-
107
-
-
18044371228
-
Androgen receptor-cofactor interactions as targets for new drug discovery
-
Chang, C.Y. et al. (2005) Androgen receptor-cofactor interactions as targets for new drug discovery. Trends Pharmacol. Sci., 26, 225-228.
-
(2005)
Trends Pharmacol. Sci.
, vol.26
, pp. 225-228
-
-
Chang, C.Y.1
-
108
-
-
17144432214
-
Androgen receptor corepressors: an overview
-
Wang, L. et al. (2005) Androgen receptor corepressors: an overview. Prostate, 63, 117-130.
-
(2005)
Prostate
, vol.63
, pp. 117-130
-
-
Wang, L.1
-
109
-
-
34248673174
-
Mechanisms of androgen receptor repression in prostate cancer
-
Powell, S.M. et al. (2006) Mechanisms of androgen receptor repression in prostate cancer. Biochem. Soc. Trans., 34(Pt 6), 1124-1127.
-
(2006)
Biochem. Soc. Trans
, vol.34
, pp. 1124-1127
-
-
Powell, S.M.1
-
110
-
-
84879492780
-
Role of aryl hydrocarbon receptor in cancer
-
Feng, S. et al. (2013) Role of aryl hydrocarbon receptor in cancer. Biochim. Biophys. Acta, 1836, 197-210.
-
(2013)
Biochim. Biophys. Acta
, vol.1836
, pp. 197-210
-
-
Feng, S.1
-
111
-
-
28344456637
-
The aryl hydrocarbon receptor constitutively represses c-myc transcription in human mammary tumor cells
-
Yang, X. et al. (2005) The aryl hydrocarbon receptor constitutively represses c-myc transcription in human mammary tumor cells. Oncogene, 24, 7869-7881.
-
(2005)
Oncogene
, vol.24
, pp. 7869-7881
-
-
Yang, X.1
-
112
-
-
0036737088
-
Combining xenoestrogens at levels below individual no-observed-effect concentrations dramatically enhances steroid hormone action
-
Rajapakse, N. et al. (2002) Combining xenoestrogens at levels below individual no-observed-effect concentrations dramatically enhances steroid hormone action. Environ. Health Perspect., 110, 917-921.
-
(2002)
Environ. Health Perspect.
, vol.110
, pp. 917-921
-
-
Rajapakse, N.1
-
113
-
-
0037090577
-
Something from "nothing"-eight weak estrogenic chemicals combined at concentrations below NOECs produce significant mixture effects
-
Silva, E. et al. (2002) Something from "nothing"-eight weak estrogenic chemicals combined at concentrations below NOECs produce significant mixture effects. Environ. Sci. Technol., 36, 1751-1756.
-
(2002)
Environ. Sci. Technol.
, vol.36
, pp. 1751-1756
-
-
Silva, E.1
-
114
-
-
37349006889
-
Ten years of mixing cocktails: a review of combination effects of endocrine-disrupting chemicals
-
Kortenkamp, A. (2007) Ten years of mixing cocktails: a review of combination effects of endocrine-disrupting chemicals. Environ. Health Perspect., 115, 98-105.
-
(2007)
Environ. Health Perspect.
, vol.115
, pp. 98-105
-
-
Kortenkamp, A.1
-
115
-
-
84875595637
-
Combinations of parabens at concentrations measured in human breast tissue can increase proliferation of MCF-7 human breast cancer cells
-
Charles, A.K. et al. (2013) Combinations of parabens at concentrations measured in human breast tissue can increase proliferation of MCF-7 human breast cancer cells. J. Appl. Toxicol., 33, 390-398.
-
(2013)
J. Appl. Toxicol.
, vol.33
, pp. 390-398
-
-
Charles, A.K.1
-
116
-
-
84856449342
-
Measurement of paraben concentrations in human breast tissue at serial locations across the breast from axilla to sternum
-
Barr, L. et al. (2012) Measurement of paraben concentrations in human breast tissue at serial locations across the breast from axilla to sternum. J. Appl. Toxicol., 32, 219-232.
-
(2012)
J. Appl. Toxicol.
, vol.32
, pp. 219-232
-
-
Barr, L.1
-
117
-
-
84875064090
-
Molecular mechanisms of oestrogen action on growth of human breast cancer cells in culture
-
Darbre, P.D. (2012) Molecular mechanisms of oestrogen action on growth of human breast cancer cells in culture. Horm. Mol. Biol. Clin. Invest., 9, 65-85.
-
(2012)
Horm. Mol. Biol. Clin. Invest.
, vol.9
, pp. 65-85
-
-
Darbre, P.D.1
-
118
-
-
33750975372
-
The role of estrogen in the initiation of breast cancer
-
Russo, J. et al. (2006) The role of estrogen in the initiation of breast cancer. J. Steroid Biochem. Mol. Biol., 102, 89-96.
-
(2006)
J. Steroid Biochem. Mol. Biol.
, vol.102
, pp. 89-96
-
-
Russo, J.1
-
119
-
-
84978607143
-
State of the Science of Endocrine Disrupting Chemicals
-
World Health Organisation, Geneva
-
Bergman, A. et al. (2013) State of the Science of Endocrine Disrupting Chemicals. United Nations Environment Programme, World Health Organisation, Geneva.
-
(2013)
United Nations Environment Programme
-
-
Bergman, A.1
-
120
-
-
84859373425
-
Hormones and endocrine-disrupting chemicals: low-dose effects and nonmonotonic dose responses
-
Vandenberg, L.N. et al. (2012) Hormones and endocrine-disrupting chemicals: low-dose effects and nonmonotonic dose responses. Endocr. Rev., 33, 378-455.
-
(2012)
Endocr. Rev.
, vol.33
, pp. 378-455
-
-
Vandenberg, L.N.1
-
121
-
-
33644699019
-
Lessons learnt from structural studies of the oestrogen receptor
-
Pike, A.C. (2006) Lessons learnt from structural studies of the oestrogen receptor. Best Pract. Res. Clin. Endocrinol. Metab., 20, 1-14.
-
(2006)
Best Pract. Res. Clin. Endocrinol. Metab.
, vol.20
, pp. 1-14
-
-
Pike, A.C.1
-
122
-
-
33646840283
-
Metalloestrogens: an emerging class of inorganic xenoestrogens with potential to add to the oestrogenic burden of the human breast
-
Darbre, P.D. (2006) Metalloestrogens: an emerging class of inorganic xenoestrogens with potential to add to the oestrogenic burden of the human breast. J. Appl. Toxicol., 26, 191-197.
-
(2006)
J. Appl. Toxicol.
, vol.26
, pp. 191-197
-
-
Darbre, P.D.1
-
123
-
-
77951088991
-
Environmental oestrogens and breast cancer:evidence for combined involvement of dietary, household and cosmetic xenoestrogens
-
Darbre, P.D. et al. (2010) Environmental oestrogens and breast cancer:evidence for combined involvement of dietary, household and cosmetic xenoestrogens. Anticancer Res., 30, 815-828.
-
(2010)
Anticancer Res.
, vol.30
, pp. 815-828
-
-
Darbre, P.D.1
-
124
-
-
0034020453
-
The estrogen receptor relative binding affinities of 188 natural and xenochemicals: structural diversity of ligands
-
Blair, R.M. et al. (2000) The estrogen receptor relative binding affinities of 188 natural and xenochemicals: structural diversity of ligands. Toxicol. Sci., 54, 138-153.
-
(2000)
Toxicol. Sci.
, vol.54
, pp. 138-153
-
-
Blair, R.M.1
-
125
-
-
84875075259
-
Environmental oestrogens and breast cancer:long-term low-dose effects of mixtures of various chemical combinations
-
Darbre, P.D. et al. (2013) Environmental oestrogens and breast cancer:long-term low-dose effects of mixtures of various chemical combinations. J. Epidemiol. Community Health, 67, 203-205.
-
(2013)
J. Epidemiol. Community Health
, vol.67
, pp. 203-205
-
-
Darbre, P.D.1
-
127
-
-
47349107464
-
The role of PPAR ligands in controlling growthrelated gene expression and their interaction with lipoperoxidation products
-
2008
-
Barrera, C. et al. (2008) The role of PPAR ligands in controlling growthrelated gene expression and their interaction with lipoperoxidation products. PPAR Res., 2008, 524671.
-
(2008)
PPAR Res
, pp. 524671
-
-
Barrera, C.1
-
128
-
-
83555165982
-
Differential genotoxicity of chemical properties and particle size of rare metal and metal oxide nanoparticles
-
Hasegawa, G. et al. (2012) Differential genotoxicity of chemical properties and particle size of rare metal and metal oxide nanoparticles. J. Appl. Toxicol., 32, 72-80.
-
(2012)
J. Appl. Toxicol.
, vol.32
, pp. 72-80
-
-
Hasegawa, G.1
-
129
-
-
0028886527
-
Accumulation of human promyelocytic leukemic (HL-60) cells at two energetic cell cycle checkpoints
-
Sweet, S. et al. (1995) Accumulation of human promyelocytic leukemic (HL-60) cells at two energetic cell cycle checkpoints. Cancer Res., 55, 5164-5167.
-
(1995)
Cancer Res.
, vol.55
, pp. 5164-5167
-
-
Sweet, S.1
-
130
-
-
70350605488
-
Size-dependent effects of tungsten carbidecobalt particles on oxygen radical production and activation of cell signaling pathways in murine epidermal cells
-
Ding, M. et al. (2009) Size-dependent effects of tungsten carbidecobalt particles on oxygen radical production and activation of cell signaling pathways in murine epidermal cells. Toxicol. Appl. Pharmacol., 241, 260-268.
-
(2009)
Toxicol. Appl. Pharmacol.
, vol.241
, pp. 260-268
-
-
Ding, M.1
-
131
-
-
62149098871
-
Genotoxic responses to titanium dioxide nanoparticles and fullerene in gpt delta transgenic MEF cells
-
Xu, A. et al. (2009) Genotoxic responses to titanium dioxide nanoparticles and fullerene in gpt delta transgenic MEF cells. Part. Fibre Toxicol., 6, 3.
-
(2009)
Part. Fibre Toxicol
, vol.6
, pp. 3
-
-
Xu, A.1
-
132
-
-
63449105617
-
Cytotoxicity and genotoxicity of silver nanoparticles in human cells
-
AshaRani, P.V. et al. (2009) Cytotoxicity and genotoxicity of silver nanoparticles in human cells. ACS Nano, 3, 279-290.
-
(2009)
ACS Nano
, vol.3
, pp. 279-290
-
-
AshaRani, P.V.1
-
133
-
-
77953649363
-
The promotion of human malignant melanoma growth by mesoporous silica nanoparticles through decreased reactive oxygen species
-
Huang, X. et al. (2010) The promotion of human malignant melanoma growth by mesoporous silica nanoparticles through decreased reactive oxygen species. Biomaterials, 31, 6142-6153.
-
(2010)
Biomaterials
, vol.31
, pp. 6142-6153
-
-
Huang, X.1
-
134
-
-
77954008507
-
Biokinetic modeling and in vitro-in vivo extrapolations
-
Blaauboer, B.J. (2010) Biokinetic modeling and in vitro-in vivo extrapolations. J. Toxicol. Environ. Health. B Crit. Rev., 13, 242-252.
-
(2010)
J. Toxicol. Environ. Health. B Crit. Rev.
, vol.13
, pp. 242-252
-
-
Blaauboer, B.J.1
-
135
-
-
77956906710
-
Incorporating human dosimetry and exposure into high-throughput in vitro toxicity screening
-
Rotroff, D.M. et al. (2010) Incorporating human dosimetry and exposure into high-throughput in vitro toxicity screening. Toxicol. Sci., 117, 348-358.
-
(2010)
Toxicol. Sci.
, vol.117
, pp. 348-358
-
-
Rotroff, D.M.1
-
136
-
-
84555187264
-
Integration of dosimetry, exposure, and high-throughput screening data in chemical toxicity assessment
-
Wetmore, B.A. et al. (2012) Integration of dosimetry, exposure, and high-throughput screening data in chemical toxicity assessment. Toxicol. Sci., 125, 157-174.
-
(2012)
Toxicol. Sci.
, vol.125
, pp. 157-174
-
-
Wetmore, B.A.1
-
137
-
-
84890409624
-
Dosimetric anchoring of in vivo and in vitro studies for perfluorooctanoate and perfluorooctanesulfonate
-
Wambaugh, J.F. et al. (2013) Dosimetric anchoring of in vivo and in vitro studies for perfluorooctanoate and perfluorooctanesulfonate. Toxicol. Sci., 136, 308-327.
-
(2013)
Toxicol. Sci.
, vol.136
, pp. 308-327
-
-
Wambaugh, J.F.1
-
138
-
-
84937695582
-
Application of reverse dosimetry to compare in vitro and in vivo estrogen receptor activity
-
Chang, X. et al. (2015) Application of reverse dosimetry to compare in vitro and in vivo estrogen receptor activity. Appl. In Vitro Toxicol., 1, 33-44.
-
(2015)
Appl. In Vitro Toxicol.
, vol.1
, pp. 33-44
-
-
Chang, X.1
-
139
-
-
84920617888
-
Altered glucose metabolism in Harvey-ras transformed MCF10A cells
-
Zheng, W. et al. (2015) Altered glucose metabolism in Harvey-ras transformed MCF10A cells. Mol. Carcinog., 54, 111-120.
-
(2015)
Mol. Carcinog.
, vol.54
, pp. 111-120
-
-
Zheng, W.1
-
140
-
-
79952228407
-
Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis
-
Guo, J.Y. et al. (2011) Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis. Genes Dev., 25, 460-470.
-
(2011)
Genes Dev.
, vol.25
, pp. 460-470
-
-
Guo, J.Y.1
-
141
-
-
77950239571
-
p53 regulates the Ras circuit to inhibit the expression of a cancer-related gene signature by various molecular pathways
-
Buganim, Y. et al. (2010) p53 regulates the Ras circuit to inhibit the expression of a cancer-related gene signature by various molecular pathways. Cancer Res., 70, 2274-2284.
-
(2010)
Cancer Res.
, vol.70
, pp. 2274-2284
-
-
Buganim, Y.1
-
142
-
-
84859709809
-
Attenuation of TGF-β signaling suppresses premature senescence in a p21-dependent manner and promotes oncogenic Ras-mediated metastatic transformation in human mammary epithelial cells
-
Lin, S. et al. (2012) Attenuation of TGF-β signaling suppresses premature senescence in a p21-dependent manner and promotes oncogenic Ras-mediated metastatic transformation in human mammary epithelial cells. Mol. Biol. Cell, 23, 1569-1581.
-
(2012)
Mol. Biol. Cell
, vol.23
, pp. 1569-1581
-
-
Lin, S.1
-
143
-
-
12644317846
-
Oncogenic H-ras stimulates tumor angiogenesis by two distinct pathways
-
Arbiser, J.L. et al. (1997) Oncogenic H-ras stimulates tumor angiogenesis by two distinct pathways. Proc. Natl Acad. Sci. USA, 94, 861-866.
-
(1997)
Proc. Natl Acad. Sci. USA
, vol.94
, pp. 861-866
-
-
Arbiser, J.L.1
-
144
-
-
65349180814
-
Increased genomic instability and altered chromosomal protein phosphorylation timing in HRAS-transformed mouse fibroblasts
-
Dunn, K.L. et al. (2009) Increased genomic instability and altered chromosomal protein phosphorylation timing in HRAS-transformed mouse fibroblasts. Genes Chromosomes Cancer, 48, 397-409.
-
(2009)
Genes Chromosomes Cancer
, vol.48
, pp. 397-409
-
-
Dunn, K.L.1
-
145
-
-
16544390524
-
K-Ras and H-Ras activation promote distinct consequences on endometrial cell survival
-
Ninomiya, Y. et al. (2004) K-Ras and H-Ras activation promote distinct consequences on endometrial cell survival. Cancer Res., 64, 2759-2765.
-
(2004)
Cancer Res.
, vol.64
, pp. 2759-2765
-
-
Ninomiya, Y.1
-
146
-
-
34147103446
-
Proapoptotic ability of oncogenic H-Ras to facilitate apoptosis induced by histone deacetylase inhibitors in human cancer cells
-
Choudhary, S. et al. (2007) Proapoptotic ability of oncogenic H-Ras to facilitate apoptosis induced by histone deacetylase inhibitors in human cancer cells. Mol. Cancer Ther., 6, 1099-1111.
-
(2007)
Mol. Cancer Ther.
, vol.6
, pp. 1099-1111
-
-
Choudhary, S.1
-
147
-
-
33845269825
-
Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication
-
Di Micco, R. et al. (2006) Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication. Nature, 444, 638-642.
-
(2006)
Nature
, vol.444
, pp. 638-642
-
-
Di Micco, R.1
-
148
-
-
84963941063
-
Discoidin domain receptor 1 is a novel transcriptional target of ZEB1 in breast epithelial cells undergoing H-Rasinduced epithelial to mesenchymal transition
-
Koh, M. et al. (2015) Discoidin domain receptor 1 is a novel transcriptional target of ZEB1 in breast epithelial cells undergoing H-Rasinduced epithelial to mesenchymal transition. Int. J. Cancer, 136, E508-E520.
-
(2015)
Int. J. Cancer
, vol.136
, pp. E508-E520
-
-
Koh, M.1
-
149
-
-
84899965504
-
H-Ras-driven tumoral maintenance is sustained through caveolin-1-dependent alterations in calcium signaling
-
Rimessi, A. et al. (2014) H-Ras-driven tumoral maintenance is sustained through caveolin-1-dependent alterations in calcium signaling. Oncogene, 33, 2329-2340.
-
(2014)
Oncogene
, vol.33
, pp. 2329-2340
-
-
Rimessi, A.1
-
150
-
-
78650201018
-
Silencing the expression of Ras family GTPase homologues decreases inflammation and joint destruction in experimental arthritis
-
de Launay, D. et al. (2010) Silencing the expression of Ras family GTPase homologues decreases inflammation and joint destruction in experimental arthritis. Am. J. Pathol., 177, 3010-3024.
-
(2010)
Am. J. Pathol.
, vol.177
, pp. 3010-3024
-
-
de Launay, D.1
-
151
-
-
77953479867
-
Oncogenic mutations regulate tumor microenvironment through induction of growth factors and angiogenic mediators
-
Wang, S.E. et al. (2010) Oncogenic mutations regulate tumor microenvironment through induction of growth factors and angiogenic mediators. Oncogene, 29, 3335-3348.
-
(2010)
Oncogene
, vol.29
, pp. 3335-3348
-
-
Wang, S.E.1
-
152
-
-
84055176157
-
c-Fos activates and physically interacts with specific enzymes of the pathway of synthesis of polyphosphoinositides
-
Alfonso Pecchio, A.R. et al. (2011) c-Fos activates and physically interacts with specific enzymes of the pathway of synthesis of polyphosphoinositides. Mol. Biol. Cell, 22, 4716-4725.
-
(2011)
Mol. Biol. Cell
, vol.22
, pp. 4716-4725
-
-
Alfonso Pecchio, A.R.1
-
153
-
-
77953906728
-
Dietary energy restriction, in part through glucocorticoid hormones, mediates the impact of 12-O-tetradecanoylphorbol-13-acetate on jun D and fra-1 in Sencar mouse epidermis
-
Przybyszewski, J. et al. (2010) Dietary energy restriction, in part through glucocorticoid hormones, mediates the impact of 12-O-tetradecanoylphorbol-13-acetate on jun D and fra-1 in Sencar mouse epidermis. Mol. Carcinog., 49, 592-602.
-
(2010)
Mol. Carcinog.
, vol.49
, pp. 592-602
-
-
Przybyszewski, J.1
-
154
-
-
0033104956
-
Control of cell cycle progression by c-Jun is p53 dependent
-
Schreiber, M. et al. (1999) Control of cell cycle progression by c-Jun is p53 dependent. Genes Dev., 13, 607-619.
-
(1999)
Genes Dev.
, vol.13
, pp. 607-619
-
-
Schreiber, M.1
-
155
-
-
84864764964
-
Differentiation-induced skin cancer suppression by FOS, p53, and TACE/ADAM17
-
Guinea-Viniegra, J. et al. (2012) Differentiation-induced skin cancer suppression by FOS, p53, and TACE/ADAM17. J. Clin. Invest., 122, 2898-2910.
-
(2012)
J. Clin. Invest.
, vol.122
, pp. 2898-2910
-
-
Guinea-Viniegra, J.1
-
156
-
-
0034528112
-
p53 and c-Jun functionally synergize in the regulation of the DNA repair gene hMSH2 in response to UV
-
Scherer, S.J. et al. (2000) p53 and c-Jun functionally synergize in the regulation of the DNA repair gene hMSH2 in response to UV. J. Biol. Chem., 275, 37469-37473.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 37469-37473
-
-
Scherer, S.J.1
-
157
-
-
0033605345
-
Recruitment of the retinoblastoma protein to c-Jun enhances transcription activity mediated through the AP-1 binding site
-
Nishitani, J. et al. (1999) Recruitment of the retinoblastoma protein to c-Jun enhances transcription activity mediated through the AP-1 binding site. J. Biol. Chem., 274, 5454-5461.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 5454-5461
-
-
Nishitani, J.1
-
158
-
-
84856041539
-
Targeting p53 via JNK pathway: a novel role of RITA for apoptotic signaling in multiple myeloma
-
Saha, M.N. et al. (2012) Targeting p53 via JNK pathway: a novel role of RITA for apoptotic signaling in multiple myeloma. PLoS One, 7, e30215.
-
(2012)
PLoS One
, vol.7
, pp. e30215
-
-
Saha, M.N.1
-
159
-
-
84880847915
-
Overexpressed DNA polymerase iota regulated by JNK/c-Jun contributes to hypermutagenesis in bladder cancer
-
Yuan, F. et al. (2013) Overexpressed DNA polymerase iota regulated by JNK/c-Jun contributes to hypermutagenesis in bladder cancer. PLoS One, 8, e69317.
-
(2013)
PLoS One
, vol.8
, pp. e69317
-
-
Yuan, F.1
-
160
-
-
0031908748
-
AP-1 (Fos/Jun) transcription factors in hematopoietic differentiation and apoptosis
-
Liebermann, D.A. et al. (1998) AP-1 (Fos/Jun) transcription factors in hematopoietic differentiation and apoptosis. Int. J. Oncol., 12, 685-700.
-
(1998)
Int. J. Oncol.
, vol.12
, pp. 685-700
-
-
Liebermann, D.A.1
-
161
-
-
0026440506
-
Cell cycle-specific metabolism of arabinosyl nucleosides in K562 human leukemia cells
-
Gandhi, V. et al. (1992) Cell cycle-specific metabolism of arabinosyl nucleosides in K562 human leukemia cells. Cancer Chemother. Pharmacol., 31, 11-17.
-
(1992)
Cancer Chemother. Pharmacol.
, vol.31
, pp. 11-17
-
-
Gandhi, V.1
-
162
-
-
0037102433
-
Telomerase is regulated by c-Jun NH2-terminal kinase in ovarian surface epithelial cells
-
Alfonso-De Matte, M.Y. et al. (2002) Telomerase is regulated by c-Jun NH2-terminal kinase in ovarian surface epithelial cells. Cancer Res., 62, 4575-4578.
-
(2002)
Cancer Res.
, vol.62
, pp. 4575-4578
-
-
Alfonso-De Matte, M.Y.1
-
163
-
-
24344466208
-
Function of AP-1 in transcription of the telomerase reverse transcriptase gene (TERT) in human and mouse cells
-
Takakura, M. et al. (2005) Function of AP-1 in transcription of the telomerase reverse transcriptase gene (TERT) in human and mouse cells. Mol. Cell. Biol., 25, 8037-8043.
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 8037-8043
-
-
Takakura, M.1
-
164
-
-
0034632055
-
Activation of mitogen-activated protein kinases is required for alpha1-adrenergic agonist-induced cell scattering in transfected HepG2 cells
-
Spector, M. et al. (2000) Activation of mitogen-activated protein kinases is required for alpha1-adrenergic agonist-induced cell scattering in transfected HepG2 cells. Exp. Cell Res., 258, 109-120.
-
(2000)
Exp. Cell Res.
, vol.258
, pp. 109-120
-
-
Spector, M.1
-
165
-
-
84883395289
-
N-myc downstream-regulated gene 1 promotes tumor inflammatory angiogenesis through JNK activation and autocrine loop of interleukin-1α by human gastric cancer cells
-
Murakami, Y. et al. (2013) N-myc downstream-regulated gene 1 promotes tumor inflammatory angiogenesis through JNK activation and autocrine loop of interleukin-1α by human gastric cancer cells. J. Biol. Chem., 288, 25025-25037.
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 25025-25037
-
-
Murakami, Y.1
-
166
-
-
49749124618
-
Molecular links between tumor angiogenesis and inflammation: inflammatory stimuli of macrophages and cancer cells as targets for therapeutic strategy
-
Ono, M. (2008) Molecular links between tumor angiogenesis and inflammation: inflammatory stimuli of macrophages and cancer cells as targets for therapeutic strategy. Cancer Sci., 99, 1501-1506.
-
(2008)
Cancer Sci.
, vol.99
, pp. 1501-1506
-
-
Ono, M.1
-
167
-
-
33750914460
-
Redox-dependent expression of cyclin D1 and cell proliferation by Nox1 in mouse lung epithelial cells
-
Ranjan, P. et al. (2006) Redox-dependent expression of cyclin D1 and cell proliferation by Nox1 in mouse lung epithelial cells. Antioxid. Redox Signal., 8, 1447-1459.
-
(2006)
Antioxid. Redox Signal.
, vol.8
, pp. 1447-1459
-
-
Ranjan, P.1
-
168
-
-
84878221140
-
Weight loss improves the adipogenic capacity of human preadipocytes and modulates their secretory profile
-
Rossmeislová, L. et al. (2013) Weight loss improves the adipogenic capacity of human preadipocytes and modulates their secretory profile. Diabetes, 62, 1990-1995.
-
(2013)
Diabetes
, vol.62
, pp. 1990-1995
-
-
Rossmeislová, L.1
-
169
-
-
84877263626
-
Abdominal obesity, independent from caloric intake, accounts for the development of intestinal tumors in Apc(1638N/+) female mice
-
Huffman, D.M. et al. (2013) Abdominal obesity, independent from caloric intake, accounts for the development of intestinal tumors in Apc(1638N/+) female mice. Cancer Prev. Res. (Phila.), 6, 177-187.
-
(2013)
Cancer Prev. Res. (Phila.)
, vol.6
, pp. 177-187
-
-
Huffman, D.M.1
-
170
-
-
84859469390
-
Muscle-derived expression of the chemokine CXCL1 attenuates diet-induced obesity and improves fatty acid oxidation in the muscle
-
Pedersen, L. et al. (2012) Muscle-derived expression of the chemokine CXCL1 attenuates diet-induced obesity and improves fatty acid oxidation in the muscle. Am. J. Physiol. Endocrinol. Metab., 302, E831-E840.
-
(2012)
Am. J. Physiol. Endocrinol. Metab
, vol.302
, pp. E831-E840
-
-
Pedersen, L.1
-
171
-
-
4143050218
-
The potential role of neutrophils in promoting the metastatic phenotype of tumors releasing interleukin-8
-
De Larco, J.E. et al. (2004) The potential role of neutrophils in promoting the metastatic phenotype of tumors releasing interleukin-8. Clin. Cancer Res., 10, 4895-4900.
-
(2004)
Clin. Cancer Res.
, vol.10
, pp. 4895-4900
-
-
De Larco, J.E.1
-
172
-
-
84891705159
-
ATM deficiency augments constitutively nuclear cyclin D1-driven genomic instability and lymphomagenesis
-
Vaites, L.P. et al. (2013) ATM deficiency augments constitutively nuclear cyclin D1-driven genomic instability and lymphomagenesis. Oncogene, 33, 129-133.
-
(2013)
Oncogene
, vol.33
, pp. 129-133
-
-
Vaites, L.P.1
-
173
-
-
84877834495
-
Interleukin-8 prevents oxidative stressinduced human endothelial cell senescence via telomerase activation
-
Shen, X.H. et al. (2013) Interleukin-8 prevents oxidative stressinduced human endothelial cell senescence via telomerase activation. Int. Immunopharmacol., 16, 261-267.
-
(2013)
Int. Immunopharmacol.
, vol.16
, pp. 261-267
-
-
Shen, X.H.1
-
174
-
-
84883435384
-
Ex vivo expansion of human outgrowth endothelial cells leads to IL-8-mediated replicative senescence and impaired vasoreparative function
-
Medina, R.J. et al. (2013) Ex vivo expansion of human outgrowth endothelial cells leads to IL-8-mediated replicative senescence and impaired vasoreparative function. Stem Cells, 31, 1657-1668.
-
(2013)
Stem Cells
, vol.31
, pp. 1657-1668
-
-
Medina, R.J.1
-
175
-
-
84864942150
-
TWIST1 associates with NF-κB subunit RELA via carboxyl-terminal WR domain to promote cell autonomous invasion through IL8 production
-
Li, S. et al. (2012) TWIST1 associates with NF-κB subunit RELA via carboxyl-terminal WR domain to promote cell autonomous invasion through IL8 production. BMC Biol., 10, 73.
-
(2012)
BMC Biol
, vol.10
, pp. 73
-
-
Li, S.1
-
176
-
-
84874396130
-
Association of cyclin D and estrogen receptor α36 with hepatocellular adenomas of female mice under chronic endoplasmic reticulum stress
-
Lau, M.Y. et al. (2013) Association of cyclin D and estrogen receptor α36 with hepatocellular adenomas of female mice under chronic endoplasmic reticulum stress. J. Gastroenterol. Hepatol., 28, 576-583.
-
(2013)
J. Gastroenterol. Hepatol.
, vol.28
, pp. 576-583
-
-
Lau, M.Y.1
-
177
-
-
84885927922
-
Anti-inflammatory effects of danshen on human vascular endothelial cells in culture
-
Stumpf, C. et al. (2013) Anti-inflammatory effects of danshen on human vascular endothelial cells in culture. Am. J. Chin. Med., 41, 1065-1077.
-
(2013)
Am. J. Chin. Med.
, vol.41
, pp. 1065-1077
-
-
Stumpf, C.1
-
178
-
-
84877154620
-
Compartment-specific activation of PPARγ governs breast cancer tumor growth, via metabolic reprogramming and symbiosis
-
Avena, P. et al. (2013) Compartment-specific activation of PPARγ governs breast cancer tumor growth, via metabolic reprogramming and symbiosis. Cell Cycle, 12, 1360-1370.
-
(2013)
Cell Cycle
, vol.12
, pp. 1360-1370
-
-
Avena, P.1
-
179
-
-
0033605677
-
Peroxisome proliferator-activated receptor gamma ligands are potent inhibitors of angiogenesis in vitro and in vivo
-
Xin, X. et al. (1999) Peroxisome proliferator-activated receptor gamma ligands are potent inhibitors of angiogenesis in vitro and in vivo. J. Biol. Chem., 274, 9116-9121.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 9116-9121
-
-
Xin, X.1
-
180
-
-
20044372348
-
Peroxisome proliferator-activated receptor gamma agonists promote TRAIL-induced apoptosis by reducing survivin levels via cyclin D3 repression and cell cycle arrest
-
Lu, M. et al. (2005) Peroxisome proliferator-activated receptor gamma agonists promote TRAIL-induced apoptosis by reducing survivin levels via cyclin D3 repression and cell cycle arrest. J. Biol. Chem., 280, 6742-6751.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 6742-6751
-
-
Lu, M.1
-
181
-
-
0036177288
-
Ligands of peroxisome proliferator-activated receptor-gamma induce apoptosis in AR42J cells
-
Masamune, A. et al. (2002) Ligands of peroxisome proliferator-activated receptor-gamma induce apoptosis in AR42J cells. Pancreas, 24, 130-138.
-
(2002)
Pancreas
, vol.24
, pp. 130-138
-
-
Masamune, A.1
-
182
-
-
33750620955
-
Ceramide induces apoptosis via a peroxisome proliferator-activated receptor gamma-dependent pathway
-
Wang, J. et al. (2006) Ceramide induces apoptosis via a peroxisome proliferator-activated receptor gamma-dependent pathway. Apoptosis, 11, 2043-2052.
-
(2006)
Apoptosis
, vol.11
, pp. 2043-2052
-
-
Wang, J.1
-
183
-
-
63849146427
-
The PPARalpha/p16INK4a pathway inhibits vascular smooth muscle cell proliferation by repressing cell cycledependent telomerase activation
-
Gizard, F. et al. (2008) The PPARalpha/p16INK4a pathway inhibits vascular smooth muscle cell proliferation by repressing cell cycledependent telomerase activation. Circ. Res., 103, 1155-1163.
-
(2008)
Circ. Res.
, vol.103
, pp. 1155-1163
-
-
Gizard, F.1
-
184
-
-
84882729383
-
Peroxisome proliferator-activated receptor γ agonist suppresses human telomerase reverse transcriptase expression and aromatase activity in eutopic endometrial stromal cells from endometriosis
-
Chang, H.J. et al. (2013) Peroxisome proliferator-activated receptor γ agonist suppresses human telomerase reverse transcriptase expression and aromatase activity in eutopic endometrial stromal cells from endometriosis. Clin. Exp. Reprod. Med., 40, 67-75.
-
(2013)
Clin. Exp. Reprod. Med.
, vol.40
, pp. 67-75
-
-
Chang, H.J.1
-
185
-
-
84874743183
-
CITED2 is a novel direct effector of peroxisome proliferator-activated receptor γ in suppressing hepatocellular carcinoma cell growth
-
Cheung, K.F. et al. (2013) CITED2 is a novel direct effector of peroxisome proliferator-activated receptor γ in suppressing hepatocellular carcinoma cell growth. Cancer, 119, 1217-1226.
-
(2013)
Cancer
, vol.119
, pp. 1217-1226
-
-
Cheung, K.F.1
-
186
-
-
0038703477
-
PPARgamma ligands and ATRA inhibit the invasion of human breast cancer cells in vitro
-
Liu, H. et al. (2003) PPARgamma ligands and ATRA inhibit the invasion of human breast cancer cells in vitro. Breast Cancer Res. Treat., 79, 63-74.
-
(2003)
Breast Cancer Res. Treat.
, vol.79
, pp. 63-74
-
-
Liu, H.1
-
187
-
-
0033049772
-
An update on the mechanisms of action of the peroxisome proliferator-activated receptors (PPARs) and their roles in inflammation and cancer
-
Gelman, L. et al. (1999) An update on the mechanisms of action of the peroxisome proliferator-activated receptors (PPARs) and their roles in inflammation and cancer. Cell. Mol. Life Sci., 55, 932-943.
-
(1999)
Cell. Mol. Life Sci.
, vol.55
, pp. 932-943
-
-
Gelman, L.1
-
188
-
-
78651397321
-
Aryl hydrocarbon receptor nuclear translocator/ hypoxia-inducible factor-1{beta} plays a critical role in maintaining glucose-stimulated anaplerosis and insulin release from pancreatic {beta}-cells
-
Pillai, R. et al. (2011) Aryl hydrocarbon receptor nuclear translocator/ hypoxia-inducible factor-1{beta} plays a critical role in maintaining glucose-stimulated anaplerosis and insulin release from pancreatic {beta}-cells. J. Biol. Chem., 286, 1014-1024.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 1014-1024
-
-
Pillai, R.1
-
189
-
-
69949113906
-
Dioxin receptor deficiency impairs angiogenesis by a mechanism involving VEGF-A depletion in the endothelium and transforming growth factor-beta overexpression in the stroma
-
Roman, A.C. et al. (2009) Dioxin receptor deficiency impairs angiogenesis by a mechanism involving VEGF-A depletion in the endothelium and transforming growth factor-beta overexpression in the stroma. J. Biol. Chem., 284, 25135-25148.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 25135-25148
-
-
Roman, A.C.1
-
190
-
-
75149115740
-
The aryl hydrocarbon receptor functions as a tumor suppressor of liver carcinogenesis
-
Fan, Y. et al. (2010) The aryl hydrocarbon receptor functions as a tumor suppressor of liver carcinogenesis. Cancer Res., 70, 212-220.
-
(2010)
Cancer Res.
, vol.70
, pp. 212-220
-
-
Fan, Y.1
-
191
-
-
33744965938
-
Aryl hydrocarbon receptor modulation of tumor necrosis factor-alpha-induced apoptosis and lysosomal disruption in a hepatoma model that is caspase-8-independent
-
Caruso, J.A. et al. (2006) Aryl hydrocarbon receptor modulation of tumor necrosis factor-alpha-induced apoptosis and lysosomal disruption in a hepatoma model that is caspase-8-independent. J. Biol. Chem., 281, 10954-10967.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 10954-10967
-
-
Caruso, J.A.1
-
192
-
-
84907854398
-
The aryl hydrocarbon receptor mediates raloxifene induced apoptosis in estrogen receptor negative hepatoma and breast cancer cells
-
O'Donnell, E.F. et al. (2014) The aryl hydrocarbon receptor mediates raloxifene induced apoptosis in estrogen receptor negative hepatoma and breast cancer cells. Cell Death Dis., 5, e1038.
-
(2014)
Cell Death Dis
, vol.5
, pp. e1038
-
-
O'Donnell, E.F.1
-
193
-
-
14944348442
-
The aryl hydrocarbon receptor predisposes hepatocytes to Fas-mediated apoptosis
-
Park, K.T. et al. (2005) The aryl hydrocarbon receptor predisposes hepatocytes to Fas-mediated apoptosis. Mol. Pharmacol., 67, 612-622.
-
(2005)
Mol. Pharmacol.
, vol.67
, pp. 612-622
-
-
Park, K.T.1
-
194
-
-
84861546395
-
Dioxin induces genomic instability in mouse embryonic fibroblasts
-
Korkalainen, M. et al. (2012) Dioxin induces genomic instability in mouse embryonic fibroblasts. PLoS One, 7, e37895.
-
(2012)
PLoS One
, vol.7
, pp. e37895
-
-
Korkalainen, M.1
-
195
-
-
33644798623
-
Activation of telomerase in BeWo cells by estrogen and 2,3,7,8-tetrachlorodibenzo-p-dioxin in co-operation with c-Myc
-
Sarkar, P. et al. (2006) Activation of telomerase in BeWo cells by estrogen and 2,3,7,8-tetrachlorodibenzo-p-dioxin in co-operation with c-Myc. Int. J. Oncol., 28, 43-51.
-
(2006)
Int. J. Oncol.
, vol.28
, pp. 43-51
-
-
Sarkar, P.1
-
196
-
-
59149083365
-
Activation of the aryl hydrocarbon receptor by TCDD inhibits senescence: a tumor promoting event? Biochem
-
Ray, S. et al. (2009) Activation of the aryl hydrocarbon receptor by TCDD inhibits senescence: a tumor promoting event? Biochem. Pharmacol., 77, 681-688.
-
(2009)
Pharmacol.
, vol.77
, pp. 681-688
-
-
Ray, S.1
-
197
-
-
84875622399
-
Action of hexachlorobenzene on tumor growth and metastasis in different experimental models
-
Pontillo, C.A. et al. (2013) Action of hexachlorobenzene on tumor growth and metastasis in different experimental models. Toxicol. Appl. Pharmacol., 268, 331-342.
-
(2013)
Toxicol. Appl. Pharmacol.
, vol.268
, pp. 331-342
-
-
Pontillo, C.A.1
-
198
-
-
84864916846
-
Aryl hydrocarbon receptor agonists induce microRNA-335 expression and inhibit lung metastasis of estrogen receptor negative breast cancer cells
-
Zhang, S. et al. (2012) Aryl hydrocarbon receptor agonists induce microRNA-335 expression and inhibit lung metastasis of estrogen receptor negative breast cancer cells. Mol. Cancer Ther., 11, 108-118.
-
(2012)
Mol. Cancer Ther.
, vol.11
, pp. 108-118
-
-
Zhang, S.1
-
199
-
-
84862271549
-
Cytokines and HCV-related disorders
-
Fallahi, P. et al. (2012) Cytokines and HCV-related disorders. Clin. Dev. Immunol., 2012, 468107.
-
(2012)
Clin. Dev. Immunol
, vol.2012
, pp. 468107
-
-
Fallahi, P.1
-
200
-
-
84906962169
-
Altered gene products involved in the malignant reprogramming of cancer stem/progenitor cells and multitargeted therapies
-
Mimeault, M. et al. (2013) Altered gene products involved in the malignant reprogramming of cancer stem/progenitor cells and multitargeted therapies. Mol. Aspects Med., 39, 3-22.
-
(2013)
Mol. Aspects Med.
, vol.39
, pp. 3-22
-
-
Mimeault, M.1
-
201
-
-
28044433677
-
Epidermal growth factor receptor and angiogenesis: opportunities for combined anticancer strategies
-
van Cruijsen, H. et al. (2005) Epidermal growth factor receptor and angiogenesis: opportunities for combined anticancer strategies. Int. J. Cancer, 117, 883-888.
-
(2005)
Int. J. Cancer
, vol.117
, pp. 883-888
-
-
van Cruijsen, H.1
-
202
-
-
77149162377
-
Epidermal growth factor receptor expression in breast cancer association with biologic phenotype and clinical outcomes
-
Rimawi, M.F. et al. (2010) Epidermal growth factor receptor expression in breast cancer association with biologic phenotype and clinical outcomes. Cancer, 116, 1234-1242.
-
(2010)
Cancer
, vol.116
, pp. 1234-1242
-
-
Rimawi, M.F.1
-
203
-
-
84855275538
-
Endosomal accumulation of the activated epidermal growth factor receptor (EGFR) induces apoptosis
-
Rush, J.S. et al. (2012) Endosomal accumulation of the activated epidermal growth factor receptor (EGFR) induces apoptosis. J. Biol. Chem., 287, 712-722.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 712-722
-
-
Rush, J.S.1
-
204
-
-
33845984583
-
EGF receptor activity modulates apoptosis induced by inhibition of the proteasome of vascular smooth muscle cells
-
Ying, W.Z. et al. (2007) EGF receptor activity modulates apoptosis induced by inhibition of the proteasome of vascular smooth muscle cells. J. Am. Soc. Nephrol., 18, 131-142.
-
(2007)
J. Am. Soc. Nephrol.
, vol.18
, pp. 131-142
-
-
Ying, W.Z.1
-
205
-
-
79952087345
-
EGFR overexpression induces activation of telomerase via PI3K/AKT-mediated phosphorylation and transcriptional regulation through Hif1-alpha in a cellular model of oral-esophageal carcinogenesis
-
Heeg, S. et al. (2011) EGFR overexpression induces activation of telomerase via PI3K/AKT-mediated phosphorylation and transcriptional regulation through Hif1-alpha in a cellular model of oral-esophageal carcinogenesis. Cancer Sci., 102, 351-360.
-
(2011)
Cancer Sci.
, vol.102
, pp. 351-360
-
-
Heeg, S.1
-
206
-
-
84882629652
-
EGF receptor activates MET through MAPK to enhance non-small cell lung carcinoma invasion and brain metastasis
-
Breindel, J.L. et al. (2013) EGF receptor activates MET through MAPK to enhance non-small cell lung carcinoma invasion and brain metastasis. Cancer Res., 73, 5053-5065.
-
(2013)
Cancer Res.
, vol.73
, pp. 5053-5065
-
-
Breindel, J.L.1
-
207
-
-
84891360060
-
EGFR inhibition induces proinflammatory cytokines via NOX4 in HNSCC
-
Fletcher, E.V. et al. (2013) EGFR inhibition induces proinflammatory cytokines via NOX4 in HNSCC. Mol. Cancer Res., 11, 1574-1584.
-
(2013)
Mol. Cancer Res.
, vol.11
, pp. 1574-1584
-
-
Fletcher, E.V.1
-
208
-
-
84890482473
-
Control of Sertoli cell metabolism by sex steroid hormones is mediated through modulation in glycolysisrelated transporters and enzymes
-
Martins, A.D. et al. (2013) Control of Sertoli cell metabolism by sex steroid hormones is mediated through modulation in glycolysisrelated transporters and enzymes. Cell Tissue Res., 354, 861-868.
-
(2013)
Cell Tissue Res.
, vol.354
, pp. 861-868
-
-
Martins, A.D.1
-
209
-
-
71249101060
-
Nuclear receptor-induced chromosomal proximity and DNA breaks underlie specific translocations in cancer
-
Lin, C. et al. (2009) Nuclear receptor-induced chromosomal proximity and DNA breaks underlie specific translocations in cancer. Cell, 139, 1069-1083.
-
(2009)
Cell
, vol.139
, pp. 1069-1083
-
-
Lin, C.1
-
210
-
-
84859101069
-
Novel senescence associated gene, YPEL3, is repressed by estrogen in ER+ mammary tumor cells and required for tamoxifen-induced cellular senescence
-
Tuttle, R. et al. (2012) Novel senescence associated gene, YPEL3, is repressed by estrogen in ER+ mammary tumor cells and required for tamoxifen-induced cellular senescence. Int. J. Cancer, 130, 2291-2299.
-
(2012)
Int. J. Cancer
, vol.130
, pp. 2291-2299
-
-
Tuttle, R.1
-
211
-
-
77954586459
-
Telomerase as an important target of androgen signaling blockade for prostate cancer treatment
-
Liu, S. et al. (2010) Telomerase as an important target of androgen signaling blockade for prostate cancer treatment. Mol. Cancer Ther., 9, 2016-2025.
-
(2010)
Mol. Cancer Ther.
, vol.9
, pp. 2016-2025
-
-
Liu, S.1
-
212
-
-
77951225229
-
Androgen receptor interacts with telomeric proteins in prostate cancer cells
-
Kim, S.H. et al. (2010) Androgen receptor interacts with telomeric proteins in prostate cancer cells. J. Biol. Chem., 285, 10472-10476.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 10472-10476
-
-
Kim, S.H.1
-
213
-
-
84857697411
-
Androgen receptor drives cellular senescence
-
Mirochnik, Y. et al. (2012) Androgen receptor drives cellular senescence. PLoS One, 7, e31052.
-
(2012)
PLoS One
, vol.7
, pp. e31052
-
-
Mirochnik, Y.1
-
214
-
-
80053152480
-
Overexpression of CXCL1 and its receptor CXCR2 promote tumor invasion in gastric cancer
-
Cheng, W.L. et al. (2011) Overexpression of CXCL1 and its receptor CXCR2 promote tumor invasion in gastric cancer. Ann. Oncol., 22, 2267-2276.
-
(2011)
Ann. Oncol.
, vol.22
, pp. 2267-2276
-
-
Cheng, W.L.1
-
215
-
-
0033304494
-
Molecular control of immune/inflammatory responses: interactions between nuclear factor-kappa B and steroid receptor-signaling pathways
-
McKay, L.I. et al. (1999) Molecular control of immune/inflammatory responses: interactions between nuclear factor-kappa B and steroid receptor-signaling pathways. Endocr. Rev., 20, 435-459.
-
(1999)
Endocr. Rev.
, vol.20
, pp. 435-459
-
-
McKay, L.I.1
-
216
-
-
43849112631
-
Estrogen signalling in cancer microenvironment and prediction of response to hormonal therapy
-
Hayashi, S. et al. (2008) Estrogen signalling in cancer microenvironment and prediction of response to hormonal therapy. J. Steroid Biochem. Mol. Biol., 109, 201-206.
-
(2008)
J. Steroid Biochem. Mol. Biol.
, vol.109
, pp. 201-206
-
-
Hayashi, S.1
-
217
-
-
84876680123
-
Local endocrine, paracrine and redox signaling networks impact estrogen and androgen crosstalk in the prostate cancer microenvironment
-
Grubisha, M.J. et al. (2013) Local endocrine, paracrine and redox signaling networks impact estrogen and androgen crosstalk in the prostate cancer microenvironment. Steroids, 78, 538-541.
-
(2013)
Steroids
, vol.78
, pp. 538-541
-
-
Grubisha, M.J.1
-
218
-
-
84910603288
-
Hypoxia diminishes the detoxification of the environmental mutagen benzo[a]pyrene
-
Schults, M.A. et al. (2014) Hypoxia diminishes the detoxification of the environmental mutagen benzo[a]pyrene. Mutagenesis, 29, 481-487.
-
(2014)
Mutagenesis
, vol.29
, pp. 481-487
-
-
Schults, M.A.1
-
219
-
-
84912046893
-
Exome-wide mutation profile in benzo[a] pyrene-derived post-stasis and immortal human mammary epithelial cells
-
775-776+48-54
-
Severson, P.L. et al. (2014) Exome-wide mutation profile in benzo[a] pyrene-derived post-stasis and immortal human mammary epithelial cells. Mutat. Res. Genet. Toxicol. Environ. Mutagen., 775-776, 48-54.
-
(2014)
Mutat. Res. Genet. Toxicol. Environ. Mutagen
-
-
Severson, P.L.1
-
220
-
-
34247144232
-
Benzo[a]pyrene-3,6-dione inhibited VEGF expression through inducing HIF-1alpha degradation
-
Li, Z.D. et al. (2007) Benzo[a]pyrene-3,6-dione inhibited VEGF expression through inducing HIF-1alpha degradation. Biochem. Biophys. Res. Commun., 357, 517-523.
-
(2007)
Biochem. Biophys. Res. Commun.
, vol.357
, pp. 517-523
-
-
Li, Z.D.1
-
221
-
-
77953543833
-
Comparative proteomic analysis of anti-benzo(a) pyrene-7,8-dihydrodiol-9,10-epoxide-transformed and normal human bronchial epithelial G0/G1 cells
-
Zhao, P. et al. (2010) Comparative proteomic analysis of anti-benzo(a) pyrene-7,8-dihydrodiol-9,10-epoxide-transformed and normal human bronchial epithelial G0/G1 cells. Chem. Biol. Interact., 186, 166-173.
-
(2010)
Chem. Biol. Interact.
, vol.186
, pp. 166-173
-
-
Zhao, P.1
-
222
-
-
84880114953
-
Dose-response relationships of polycyclic aromatic hydrocarbons exposure and oxidative damage to DNA and lipid in coke oven workers
-
Kuang, D. et al. (2013) Dose-response relationships of polycyclic aromatic hydrocarbons exposure and oxidative damage to DNA and lipid in coke oven workers. Environ. Sci. Technol., 47, 7446-7456.
-
(2013)
Environ. Sci. Technol.
, vol.47
, pp. 7446-7456
-
-
Kuang, D.1
-
223
-
-
84865188332
-
Low-dose gamma-irradiation inhibits IL-6 secretion from human lung fibroblasts that promotes bronchial epithelial cell transformation by cigarette-smoke carcinogen
-
Chen, W. et al. (2012) Low-dose gamma-irradiation inhibits IL-6 secretion from human lung fibroblasts that promotes bronchial epithelial cell transformation by cigarette-smoke carcinogen. Carcinogenesis, 33, 1368-1374.
-
(2012)
Carcinogenesis
, vol.33
, pp. 1368-1374
-
-
Chen, W.1
-
224
-
-
84873703791
-
Withaferin A suppresses tumor promoter 12-O-tetradecanoylphorbol 13-acetate-induced decreases in isocitrate dehydrogenase 1 activity and mitochondrial function in skin epidermal JB6 cells
-
Li, W. et al. (2013) Withaferin A suppresses tumor promoter 12-O-tetradecanoylphorbol 13-acetate-induced decreases in isocitrate dehydrogenase 1 activity and mitochondrial function in skin epidermal JB6 cells. Cancer Sci., 104, 143-148.
-
(2013)
Cancer Sci.
, vol.104
, pp. 143-148
-
-
Li, W.1
-
225
-
-
42049086093
-
Chemopreventive activity of lantadenes on twostage carcinogenesis model in Swiss albino mice: AP-1 (c-jun), NFkappaB (p65) and P53 expression by ELISA and immunohistochemical localization
-
Kaur, J. et al. (2008) Chemopreventive activity of lantadenes on twostage carcinogenesis model in Swiss albino mice: AP-1 (c-jun), NFkappaB (p65) and P53 expression by ELISA and immunohistochemical localization. Mol. Cell. Biochem., 314, 1-8.
-
(2008)
Mol. Cell. Biochem.
, vol.314
, pp. 1-8
-
-
Kaur, J.1
-
226
-
-
33644868271
-
Attenuation of BPDE-induced p53 accumulation by TPA is associated with a decrease in stability and phosphorylation of p53 and downregulation of NFkappaB activation: role of p38 MAP kinase
-
Mukherjee, J.J. et al. (2006) Attenuation of BPDE-induced p53 accumulation by TPA is associated with a decrease in stability and phosphorylation of p53 and downregulation of NFkappaB activation: role of p38 MAP kinase. Carcinogenesis, 27, 631-638.
-
(2006)
Carcinogenesis
, vol.27
, pp. 631-638
-
-
Mukherjee, J.J.1
-
227
-
-
77956061891
-
The induction of senescence-like growth arrest by protein kinase C-activating diterpene esters in solid tumor cells
-
Mason, S.A. et al. (2010) The induction of senescence-like growth arrest by protein kinase C-activating diterpene esters in solid tumor cells. Invest. New Drugs, 28, 575-586.
-
(2010)
Invest. New Drugs
, vol.28
, pp. 575-586
-
-
Mason, S.A.1
-
228
-
-
50349085285
-
Phorbol ester-induced apoptosis and senescence in cancer cell models
-
Xiao, L. et al. (2008) Phorbol ester-induced apoptosis and senescence in cancer cell models. Methods Enzymol., 446, 123-139.
-
(2008)
Methods Enzymol.
, vol.446
, pp. 123-139
-
-
Xiao, L.1
-
229
-
-
0032856186
-
TPA-enhanced motility and invasion in a highly metastatic variant (L-10) of human rectal adenocarcinoma cell line RCM-1: selective role of PKC-alpha and its inhibition by a combination of PDBu-induced PKC downregulation and antisense oligonucleotides treatment
-
Shimao, Y. et al. (1999) TPA-enhanced motility and invasion in a highly metastatic variant (L-10) of human rectal adenocarcinoma cell line RCM-1: selective role of PKC-alpha and its inhibition by a combination of PDBu-induced PKC downregulation and antisense oligonucleotides treatment. Clin. Exp. Metastasis, 17, 351-360.
-
(1999)
Clin. Exp. Metastasis
, vol.17
, pp. 351-360
-
-
Shimao, Y.1
-
230
-
-
84876122662
-
Chemopreventive effects of the juice of Vitis coignetiae Pulliat on two-stage mouse skin carcinogenesis
-
Arimoto-Kobayashi, S. et al. (2013) Chemopreventive effects of the juice of Vitis coignetiae Pulliat on two-stage mouse skin carcinogenesis. Nutr. Cancer, 65, 440-450.
-
(2013)
Nutr. Cancer
, vol.65
, pp. 440-450
-
-
Arimoto-Kobayashi, S.1
-
231
-
-
80052735758
-
Nordihydroguaiaretic acid from creosote bush (Larrea tridentata) mitigates 12-O-tetradecanoylphorbol-13-acetateinduced inflammatory and oxidative stress responses of tumor promotion cascade in mouse skin
-
Rahman, S. et al. (2011) Nordihydroguaiaretic acid from creosote bush (Larrea tridentata) mitigates 12-O-tetradecanoylphorbol-13-acetateinduced inflammatory and oxidative stress responses of tumor promotion cascade in mouse skin. Evid. Based Complement. Alternat. Med., 2011, 734785.
-
(2011)
Evid. Based Complement. Alternat. Med
, vol.2011
, pp. 734785
-
-
Rahman, S.1
-
232
-
-
84877810999
-
Dysregulation of pathways involved in the processing of cancer and microenvironment information in MCA + TPA transformed C3H/10T1/2 cells
-
Priya, S. et al. (2013) Dysregulation of pathways involved in the processing of cancer and microenvironment information in MCA + TPA transformed C3H/10T1/2 cells. In Vitro Cell. Dev. Biol. Anim., 49, 295-305.
-
(2013)
In Vitro Cell. Dev. Biol. Anim.
, vol.49
, pp. 295-305
-
-
Priya, S.1
-
233
-
-
84904987785
-
Prenatal exposure to bisphenol A at the reference dose impairs mitochondria in the heart of neonatal rats
-
Jiang, Y. et al. (2013) Prenatal exposure to bisphenol A at the reference dose impairs mitochondria in the heart of neonatal rats. J. Appl. Toxicol., 34, 1012-1022.
-
(2013)
J. Appl. Toxicol.
, vol.34
, pp. 1012-1022
-
-
Jiang, Y.1
-
234
-
-
84874079652
-
Set, a putative oncogene, as a biomarker for prenatal exposure to bisphenol A
-
Lee, H.S. et al. (2012) Set, a putative oncogene, as a biomarker for prenatal exposure to bisphenol A. Asian Pac. J. Cancer Prev., 13, 2711-2715.
-
(2012)
Asian Pac. J. Cancer Prev.
, vol.13
, pp. 2711-2715
-
-
Lee, H.S.1
-
235
-
-
84874765558
-
Bisphenol-A-induced inactivation of the p53 axis underlying deregulation of proliferation kinetics, and cell death in non-malignant human breast epithelial cells
-
Dairkee, S.H. et al. (2013) Bisphenol-A-induced inactivation of the p53 axis underlying deregulation of proliferation kinetics, and cell death in non-malignant human breast epithelial cells. Carcinogenesis, 34, 703-712.
-
(2013)
Carcinogenesis
, vol.34
, pp. 703-712
-
-
Dairkee, S.H.1
-
236
-
-
80053954482
-
Prenatal exposure to bisphenol A promotes angiogenesis and alters steroid-mediated responses in the mammary glands of cycling rats
-
Durando, M. et al. (2011) Prenatal exposure to bisphenol A promotes angiogenesis and alters steroid-mediated responses in the mammary glands of cycling rats. J. Steroid Biochem. Mol. Biol., 127, 35-43.
-
(2011)
J. Steroid Biochem. Mol. Biol.
, vol.127
, pp. 35-43
-
-
Durando, M.1
-
237
-
-
78650555388
-
Bisphenol A impairs the double-strand break repair machinery in the germline and causes chromosome abnormalities
-
Allard, P. et al. (2010) Bisphenol A impairs the double-strand break repair machinery in the germline and causes chromosome abnormalities. Proc. Natl Acad. Sci. USA, 107, 20405-20410.
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 20405-20410
-
-
Allard, P.1
-
238
-
-
21344437721
-
Cytotoxicity and apoptosis-inducing activity of bisphenol A and hydroquinone in HL-60 cells
-
Terasaka, H. et al. (2005) Cytotoxicity and apoptosis-inducing activity of bisphenol A and hydroquinone in HL-60 cells. Anticancer Res., 25(3B), 2241-2247.
-
(2005)
Anticancer Res
, vol.25
, Issue.3 B
, pp. 2241-2247
-
-
Terasaka, H.1
-
239
-
-
0036295411
-
Bisphenol A induces apoptosis and G2-to-M arrest of ovarian granulosa cells
-
Xu, J. et al. (2002) Bisphenol A induces apoptosis and G2-to-M arrest of ovarian granulosa cells. Biochem. Biophys. Res. Commun., 292, 456-462.
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.292
, pp. 456-462
-
-
Xu, J.1
-
240
-
-
80755144021
-
Activation of the mTOR pathway by low levels of xenoestrogens in breast epithelial cells from high-risk women
-
Goodson, W.H. III et al. (2011) Activation of the mTOR pathway by low levels of xenoestrogens in breast epithelial cells from high-risk women. Carcinogenesis, 32, 1724-1733.
-
(2011)
Carcinogenesis
, vol.32
, pp. 1724-1733
-
-
Goodson, W.H.1
-
241
-
-
4644248259
-
Bisphenol A from dental polycarbonate crown upregulates the expression of hTERT
-
Takahashi, A. et al. (2004) Bisphenol A from dental polycarbonate crown upregulates the expression of hTERT. J. Biomed. Mater. Res. B Appl. Biomater., 71, 214-221.
-
(2004)
J. Biomed. Mater. Res. B Appl. Biomater.
, vol.71
, pp. 214-221
-
-
Takahashi, A.1
-
242
-
-
76049118214
-
Environmental endocrine disruptors promote invasion and metastasis of SK-N-SH human neuroblastoma cells
-
Zhu, H. et al. (2010) Environmental endocrine disruptors promote invasion and metastasis of SK-N-SH human neuroblastoma cells. Oncol. Rep., 23, 129-139.
-
(2010)
Oncol. Rep.
, vol.23
, pp. 129-139
-
-
Zhu, H.1
-
243
-
-
84859931209
-
Bisphenol AF may cause testosterone reduction by directly affecting testis function in adult male rats
-
Feng, Y. et al. (2012) Bisphenol AF may cause testosterone reduction by directly affecting testis function in adult male rats. Toxicol. Lett., 211, 201-209.
-
(2012)
Toxicol. Lett.
, vol.211
, pp. 201-209
-
-
Feng, Y.1
-
244
-
-
84874323101
-
Mechanism of perfluorooctanesulfonate (PFOS)-induced apoptosis in the immunocyte
-
Zhang, Y.H. et al. (2013) Mechanism of perfluorooctanesulfonate (PFOS)-induced apoptosis in the immunocyte. J. Immunotoxicol., 10, 49-58.
-
(2013)
J. Immunotoxicol.
, vol.10
, pp. 49-58
-
-
Zhang, Y.H.1
-
245
-
-
77951245633
-
Perfluorooctane sulfonate (PFOS) induces reactive oxygen species (ROS) production in human microvascular endothelial cells: role in endothelial permeability
-
Qian, Y. et al. (2010) Perfluorooctane sulfonate (PFOS) induces reactive oxygen species (ROS) production in human microvascular endothelial cells: role in endothelial permeability. J. Toxicol. Environ. Health A, 73, 819-836.
-
(2010)
J. Toxicol. Environ. Health A
, vol.73
, pp. 819-836
-
-
Qian, Y.1
-
246
-
-
77953916413
-
Genotoxic potential of the perfluorinated chemicals PFOA, PFOS, PFBS, PFNA and PFHxA in human HepG2 cells
-
Eriksen, K.T. et al. (2010) Genotoxic potential of the perfluorinated chemicals PFOA, PFOS, PFBS, PFNA and PFHxA in human HepG2 cells. Mutat. Res., 700, 39-43.
-
(2010)
Mutat. Res.
, vol.700
, pp. 39-43
-
-
Eriksen, K.T.1
-
247
-
-
84878498566
-
PFOS-induced apoptosis through mitochondrion- dependent pathway in human-hamster hybrid cells
-
Wang, X. et al. (2013) PFOS-induced apoptosis through mitochondrion- dependent pathway in human-hamster hybrid cells. Mutat. Res., 754, 51-57.
-
(2013)
Mutat. Res.
, vol.754
, pp. 51-57
-
-
Wang, X.1
-
248
-
-
84872269797
-
Perfluorooctane sulfonate-induced apoptosis of cerebellar granule cells is mediated by ERK 1/2 pathway
-
Lee, Y.J. et al. (2013) Perfluorooctane sulfonate-induced apoptosis of cerebellar granule cells is mediated by ERK 1/2 pathway. Chemosphere, 90, 1597-1602.
-
(2013)
Chemosphere
, vol.90
, pp. 1597-1602
-
-
Lee, Y.J.1
-
249
-
-
78650444079
-
Effects of perfluorooctane sulfonate (PFOS) exposure on markers of inflammation in female B6C3F1 mice
-
Mollenhauer, M.A. et al. (2011) Effects of perfluorooctane sulfonate (PFOS) exposure on markers of inflammation in female B6C3F1 mice. J. Environ. Sci. Health A Tox. Hazard. Subst. Environ. Eng., 46, 97-108.
-
(2011)
J. Environ. Sci. Health A Tox. Hazard. Subst. Environ. Eng.
, vol.46
, pp. 97-108
-
-
Mollenhauer, M.A.1
-
250
-
-
84860634115
-
Environmental nitration processes enhance the mutagenic potency of aromatic compounds
-
Bonnefoy, A. et al. (2012) Environmental nitration processes enhance the mutagenic potency of aromatic compounds. Environ. Toxicol., 27, 321-331.
-
(2012)
Environ. Toxicol.
, vol.27
, pp. 321-331
-
-
Bonnefoy, A.1
-
251
-
-
0346156024
-
PPARalpha agonist-induced rodent tumors:modes of action and human relevance
-
Klaunig, J.E. et al. (2003) PPARalpha agonist-induced rodent tumors:modes of action and human relevance. Crit. Rev. Toxicol., 33, 655-780.
-
(2003)
Crit. Rev. Toxicol.
, vol.33
, pp. 655-780
-
-
Klaunig, J.E.1
-
252
-
-
0023943862
-
Induction of hepatic peroxisome proliferation in mice by lactofen, a diphenyl ether herbicide
-
Butler, E.G. et al. (1988) Induction of hepatic peroxisome proliferation in mice by lactofen, a diphenyl ether herbicide. Toxicol. Appl. Pharmacol., 93, 72-80.
-
(1988)
Toxicol. Appl. Pharmacol.
, vol.93
, pp. 72-80
-
-
Butler, E.G.1
-
253
-
-
0029082945
-
Cytotoxic effects of postharvest fungicides, ortho-phenylphenol, thiabendazole and imazalil, on isolated rat hepatocytes
-
Nakagawa, Y. et al. (1995) Cytotoxic effects of postharvest fungicides, ortho-phenylphenol, thiabendazole and imazalil, on isolated rat hepatocytes. Life Sci., 57, 1433-1440.
-
(1995)
Life Sci.
, vol.57
, pp. 1433-1440
-
-
Nakagawa, Y.1
-
254
-
-
80053009778
-
Environmental impact on vascular development predicted by high-throughput screening
-
Kleinstreuer, N.C. et al. (2011) Environmental impact on vascular development predicted by high-throughput screening. Environ. Health Perspect., 119, 1596-1603.
-
(2011)
Environ. Health Perspect.
, vol.119
, pp. 1596-1603
-
-
Kleinstreuer, N.C.1
-
255
-
-
78650265792
-
Toxicologic evaluation of imazalil with particular reference to genotoxic and teratogenic potentials
-
Sişman, T. et al. (2010) Toxicologic evaluation of imazalil with particular reference to genotoxic and teratogenic potentials. Toxicol. Ind. Health, 26, 641-648.
-
(2010)
Toxicol. Ind. Health
, vol.26
, pp. 641-648
-
-
Sişman, T.1
-
256
-
-
84555204249
-
The effect of ketamine with remifentanil for improving the quality of anaesthesia and recovery in paediatric patients undergoing middle-ear ventilation tube insertion
-
Lee, J.A. et al. (2011) The effect of ketamine with remifentanil for improving the quality of anaesthesia and recovery in paediatric patients undergoing middle-ear ventilation tube insertion. J. Int. Med. Res., 39, 2239-2246.
-
(2011)
J. Int. Med. Res.
, vol.39
, pp. 2239-2246
-
-
Lee, J.A.1
-
257
-
-
84878424809
-
A C. elegans screening platform for the rapid assessment of chemical disruption of germline function
-
Allard, P. et al. (2013) A C. elegans screening platform for the rapid assessment of chemical disruption of germline function. Environ. Health Perspect., 121, 717-724.
-
(2013)
Environ. Health Perspect.
, vol.121
, pp. 717-724
-
-
Allard, P.1
-
258
-
-
0037376684
-
Role of reactive oxygen species in organophosphate insecticide phosalone toxicity in erythrocytes in vitro
-
Altuntas, I. et al. (2003) Role of reactive oxygen species in organophosphate insecticide phosalone toxicity in erythrocytes in vitro. Toxicol. In Vitro, 17, 153-157.
-
(2003)
Toxicol. In Vitro
, vol.17
, pp. 153-157
-
-
Altuntas, I.1
-
259
-
-
84876249577
-
Targeting the RAS oncogene
-
Takashima, A. et al. (2013) Targeting the RAS oncogene. Expert Opin. Ther. Targets, 17, 507-531.
-
(2013)
Expert Opin. Ther. Targets
, vol.17
, pp. 507-531
-
-
Takashima, A.1
-
260
-
-
17044423833
-
Carcinogenic polycyclic aromatic hydrocarbon-DNA adducts and mechanism of action
-
Baird, W.M. et al. (2005) Carcinogenic polycyclic aromatic hydrocarbon-DNA adducts and mechanism of action. Environ. Mol. Mutagen., 45, 106-114.
-
(2005)
Environ. Mol. Mutagen.
, vol.45
, pp. 106-114
-
-
Baird, W.M.1
-
261
-
-
84888086414
-
The carcinogenicity of air pollution
-
Loomis, D. et al. (2013) The carcinogenicity of air pollution. Lancet Oncol., 14, 1262-1263.
-
(2013)
Lancet Oncol.
, vol.14
, pp. 1262-1263
-
-
Loomis, D.1
-
262
-
-
84930754498
-
Identification of pathway based toxicity in the Balb/c 3T3 cell model
-
Vitro., in press
-
Vaccari, M. et al. (2015) Identification of pathway based toxicity in the Balb/c 3T3 cell model. Toxicol. In Vitro., in press.
-
(2015)
Toxicol
-
-
Vaccari, M.1
-
263
-
-
84902308088
-
Nanomolar levels of PAHs in extracts from urban air induce MAPK signaling in HepG2 cells
-
Jarvis, I.W. et al. (2014) Nanomolar levels of PAHs in extracts from urban air induce MAPK signaling in HepG2 cells. Toxicol. Lett., 229, 25-32.
-
(2014)
Toxicol. Lett.
, vol.229
, pp. 25-32
-
-
Jarvis, I.W.1
-
264
-
-
27144546804
-
Harvey-ras gene expression and epidermal cell proliferation in dibenzo[a,l]pyrene-treated early preneoplastic SENCAR mouse skin
-
Khan, G.A. et al. (2005) Harvey-ras gene expression and epidermal cell proliferation in dibenzo[a,l]pyrene-treated early preneoplastic SENCAR mouse skin. J. Invest. Dermatol., 125, 567-574.
-
(2005)
J. Invest. Dermatol.
, vol.125
, pp. 567-574
-
-
Khan, G.A.1
-
265
-
-
0033948673
-
DNA adduct measurements, cell proliferation and tumor mutation induction in relation to tumor formation in B6C3F1 mice fed coal tar or benzo[a]pyrene
-
Culp, S.J. et al. (2000) DNA adduct measurements, cell proliferation and tumor mutation induction in relation to tumor formation in B6C3F1 mice fed coal tar or benzo[a]pyrene. Carcinogenesis, 21, 1433-1440.
-
(2000)
Carcinogenesis
, vol.21
, pp. 1433-1440
-
-
Culp, S.J.1
-
266
-
-
84914142827
-
Nature, nurture and epigenetics
-
Crews, D. et al. (2014) Nature, nurture and epigenetics. Mol. Cell. Endocrinol., 398, 42-52.
-
(2014)
Mol. Cell. Endocrinol.
, vol.398
, pp. 42-52
-
-
Crews, D.1
-
267
-
-
84891891996
-
Environmental epigenetics and its implication on disease risk and health outcomes
-
Ho, S.M. et al. (2012) Environmental epigenetics and its implication on disease risk and health outcomes. ILAR J., 53, 289-305.
-
(2012)
ILAR J.
, vol.53
, pp. 289-305
-
-
Ho, S.M.1
-
268
-
-
77957737086
-
Epigenetic events in tumorigenesis: putting the pieces together
-
Pogribny, I.P. (2010) Epigenetic events in tumorigenesis: putting the pieces together. Exp. Oncol., 32, 132-136.
-
(2010)
Exp. Oncol.
, vol.32
, pp. 132-136
-
-
Pogribny, I.P.1
-
269
-
-
79954527846
-
Role of epigenetic events in chemical carcinogenesis- a justification for incorporating epigenetic evaluations in cancer risk assessment
-
Koturbash, I. et al. (2011) Role of epigenetic events in chemical carcinogenesis- a justification for incorporating epigenetic evaluations in cancer risk assessment. Toxicol. Mech. Methods, 21, 289-297.
-
(2011)
Toxicol. Mech. Methods
, vol.21
, pp. 289-297
-
-
Koturbash, I.1
-
270
-
-
84869046076
-
Environmental toxicants, epigenetics, and cancer
-
Pogribny, I.P. et al. (2013) Environmental toxicants, epigenetics, and cancer. Adv. Exp. Med. Biol., 754, 215-232.
-
(2013)
Adv. Exp. Med. Biol.
, vol.754
, pp. 215-232
-
-
Pogribny, I.P.1
-
271
-
-
29244473120
-
Glial metabolites of tryptophan and excitotoxicity:coming unglued
-
Coyle, J.T. (2006) Glial metabolites of tryptophan and excitotoxicity:coming unglued. Exp. Neurol., 197, 4-7.
-
(2006)
Exp. Neurol.
, vol.197
, pp. 4-7
-
-
Coyle, J.T.1
-
272
-
-
84937707779
-
IARC Monograph
-
IARC (2014) IARC Monograph. Vol. 106. IARC, p. 97.
-
(2014)
IARC
, vol.106
, pp. 97
-
-
-
273
-
-
0028526737
-
Assessing human health effects from chemical contaminants in drinking water
-
Cohn, P.D. et al. (1994) Assessing human health effects from chemical contaminants in drinking water. New Jersey Med., 91, 719-722.
-
(1994)
New Jersey Med.
, vol.91
, pp. 719-722
-
-
Cohn, P.D.1
-
274
-
-
0025121323
-
Drinking water contamination and the incidence of leukemia: an ecologic study
-
Fagliano, J. et al. (1990) Drinking water contamination and the incidence of leukemia: an ecologic study. Am. J. Public Health, 80, 1209-1212.
-
(1990)
Am. J. Public Health
, vol.80
, pp. 1209-1212
-
-
Fagliano, J.1
-
275
-
-
23844523425
-
Complementing the genome with an exposome. The outstanding challenge of environmental exposure measurement in molecular epidemiology
-
Wild, C.B. (2005) Complementing the genome with an exposome. The outstanding challenge of environmental exposure measurement in molecular epidemiology. Cancer Epidemiol. Biomarkers Prev., 14, 1847-1850.
-
(2005)
Cancer Epidemiol. Biomarkers Prev.
, vol.14
, pp. 1847-1850
-
-
Wild, C.B.1
-
276
-
-
84906854618
-
The sulfatase pathway for estrogen formation:targets for the treatment and diagnosis of hormone-associated tumors
-
Secky, L. et al. (2013) The sulfatase pathway for estrogen formation:targets for the treatment and diagnosis of hormone-associated tumors. J. Drug Deliv., 2013, 957605.
-
(2013)
J. Drug Deliv
, vol.2013
, pp. 957605
-
-
Secky, L.1
-
277
-
-
84859816587
-
Repeat estradiol exposure differentially regulates protein expression patterns for estrogen receptor and E-cadherin in older mouse ovarian surface epithelium: implications for replacement and adjuvant hormone therapies?
-
Gulliver, L.S. et al. (2012) Repeat estradiol exposure differentially regulates protein expression patterns for estrogen receptor and E-cadherin in older mouse ovarian surface epithelium: implications for replacement and adjuvant hormone therapies? Steroids, 77, 674-685.
-
(2012)
Steroids
, vol.77
, pp. 674-685
-
-
Gulliver, L.S.1
-
278
-
-
84937697416
-
Estradiol synthesis and metabolism and risk of ovarian cancer in older women taking prescribed or plantderived estrogen supplementation
-
in press
-
Gulliver Linda, S.M. (2015) Estradiol synthesis and metabolism and risk of ovarian cancer in older women taking prescribed or plantderived estrogen supplementation. J Steroids Hormone Res., in press.
-
(2015)
J Steroids Hormone Res
-
-
Gulliver Linda, S.M.1
-
279
-
-
0020479852
-
Growth activation of resting cells: induction of balanced and imbalanced growth
-
Zetterberg, A. et al. (1982) Growth activation of resting cells: induction of balanced and imbalanced growth. Ann. N.Y. Acad. Sci., 397, 130-147.
-
(1982)
Ann. N.Y. Acad. Sci.
, vol.397
, pp. 130-147
-
-
Zetterberg, A.1
-
280
-
-
0021268829
-
The relative effects of different types of growth factors on DNA replication, mitosis, and cellular enlargement
-
Zetterberg, A. et al. (1984) The relative effects of different types of growth factors on DNA replication, mitosis, and cellular enlargement. Cytometry, 5, 368-375.
-
(1984)
Cytometry
, vol.5
, pp. 368-375
-
-
Zetterberg, A.1
-
281
-
-
0025953484
-
Growth at the cellular level
-
Ekström, W. et al. (1992) Growth at the cellular level. Acta Ped. Scand., 377, 35-39.
-
(1992)
Acta Ped. Scand.
, vol.377
, pp. 35-39
-
-
Ekström, W.1
-
282
-
-
0020554171
-
Phosphate and the requirements for DNA replication in normal and virus transformed 3T3 cells
-
Engström, W. et al. (1983) Phosphate and the requirements for DNA replication in normal and virus transformed 3T3 cells. Biochemical J., 214, 695-702
-
(1983)
Biochemical J
, vol.214
, pp. 695-702
-
-
Engström, W.1
-
283
-
-
0029812273
-
Growth factors and apoptosis
-
Granérus, M. et al. (1996) Growth factors and apoptosis. Cell Prolif., 29, 309-314.
-
(1996)
Cell Prolif.
, vol.29
, pp. 309-314
-
-
Granérus, M.1
-
284
-
-
84865093110
-
Review: the effect of insulin-like growth factor II in the regulation of tumour cell growth in vitro and tumourigenesis in vivo
-
Halje, M. et al. (2012) Review: the effect of insulin-like growth factor II in the regulation of tumour cell growth in vitro and tumourigenesis in vivo. In Vivo, 26, 519-526.
-
(2012)
In Vivo
, vol.26
, pp. 519-526
-
-
Halje, M.1
-
285
-
-
84877874915
-
IGF in development and disease
-
Bergman, D. et al. IGF in development and disease. Gerontology, 59, 240-249.
-
Gerontology
, vol.59
, pp. 240-249
-
-
Bergman, D.1
-
286
-
-
79957977839
-
The pursuit of oncotargets through understanding defective cell cycle regulation
-
Qiao, M. et al. (2014) The pursuit of oncotargets through understanding defective cell cycle regulation. Oncotarget 1, 544-551.
-
(2014)
Oncotarget
, vol.1
, pp. 544-551
-
-
Qiao, M.1
|