Epithelial Cells of the Bronchiole

Comparative Biology of the Normal Lung: Second Edition

Volumn , Issue , 2015, Pages 83-92

  Plopper, Charles G ^a   Hyde, Dallas M ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Bronchioles; Distal conducting airways; Epithelium; Gas exchange area

Indexed keywords

EID: 84939609822     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-0-12-404577-4.00007-2     Document Type: Chapter

References (40)

1. Baskerville A., Olson I.A. The ultrastructure of the bronchiolar epithelium of the pig (Abstr). Proc. Anat. Soc. G. B. & I 1969, 15-16.
2. Boers J.E., Ambergen A.W., Thunnissen F.B. Number and proliferation of clara cells in normal human airway epithelium. Am. J. Respir. Crit. Care Med. 1999, 159:1585-1591.
3. Chang L.Y., Mercer R.R., Stockstill B.L., et al. Effects of low levels of NO2 on terminal bronchiolar cells and its relative toxicity compared to O3. Toxicol. Appl. Pharmacol. 1988, 96:451-464.
4. Christensen T.G., Breuer R., Hornstra L.J., Lucey E.C., Snider G.L. The ultrastructure of hamster bronchial epithelium. Exp. Lung Res. 1987, 13:253-277.
5. Christensen T.G., Breuer R., Hornstra L.J., Lucey E.C., Stone P.J., Snider G.L. An ultrastructural study of the response of hamster bronchial epithelium to human neutrophil elastase. Exp. Lung Res. 1987, 13:279-297.
6. Cutz E., Conen P.E. Ultrastructure and cytochemistry of Clara cells. Am. J. Pathol. 1971, 62:127-141.
7. Devereux T.R., Domin B.A., Philpot R.M. Xenobiotic metabolism by isolated pulmonary cells. Pharmacol. Ther. 1989, 41:243-256.
8. Florens M., Sapoval B., Filoche M. An anatomical and functional model of the human tracheobronchial tree. J. Appl. Physiol. 2011, 110:756-763.
9. Garcia O., Carraro G., Navarro S., et al. Cell-based therapies for lung disease. Br. Med. Bull. 2012, 101:147-161.
10. Haefeli-Bleuer B., Weibel E.R. Morphometry of the human pulmonary acinus. Anat. Rec. 1988, 220:401-414.
11. Hyde D.M., Samuelson D.A., Blakeney W.H., Kosch P.C. A correlative light microscopy, transmission and scanning electron microscopy study of the ferret lung. Scan Electron Microsc. 1979, 891-898.
12. Hyde D.M., Plopper C.G., Kass P.H., Alley J.L. Estimation of cell numbers and volumes of bronchiolar epithelium during rabbit lung maturation. Am. J. Anat. 1983, 167:359-370.
13. Hyde D.M., Plopper C.G., Weir A.J., et al. Peribronchiolar fibrosis in lungs of cats chronically exposed to diesel exhaust. Lab. Invest. 1985, 52:195-206.
14. Jarkovska D. Ultrastructure of the epithelium of the respiratory bronchioles in man. Folia Morphol. 1970, 18:352-358. passim.
15. Lee D., Fanucchi M.V., Plopper C.G., Fung J., Wexler A.S. Pulmonary architecture in the conducting regions of six rats. Anat. Rec. (Hoboken) 2008, 291:916-926.
16. Mariassy A.T., Plopper C.G. Tracheobronchial epithelium of the sheep: I. Quantitative light-microscopic study of epithelial cell abundance, and distribution. Anat. Rec. 1983, 205:263-275.
17. Mariassy A.T., Plopper C.G., Dungworth D.L. Characteristics of bovine lung as observed by scanning electron microscopy. Anat. Rec. 1975, 183:13-26.
18. Massaro G.D. Nonciliated bronchiolar epithelial (clara) cells. Lung Cell Biology 1989, 81-114. Marcel Dekker, New York. D. Massaro (Ed.).
19. Mercer R.R., Russell M.L., Roggli V.L., Crapo J.D. Cell number and distribution in human and rat airways. Am. J. Respir. Cell Mol. Biol. 1994, 10:613-624.
20. Moffatt R.K., Hyde D.M., Plopper C.G., Tyler W.S., Putney L.F. Ozone-induced adaptive and reactive cellular changes in respiratory bronchioles of bonnet monkeys. Exp. Lung Res. 1987, 12:57-74.
21. Onuma K., Ebina M., Takahashi T., Nukiwa T. Irregularity of airway branching in a mouse bronchial tree: a 3-D morphometric study. Tohoku J. Exp. Med. 2001, 194:157-164.
22. Pack R.J., Al-Ugaily L.H., Morris G., Widdicombe J.G. The distribution and structure of cells in the tracheal epithelium of the mouse. Cell. Tissue Res. 1980, 208:65-84.
23. Pack R.J., Al-Ugaily L.H., Morris G. The cells of the tracheobronchial epithelium of the mouse: a quantitative light and electron microscope study. J. Anat. 1981, 132:71-84.
24. Plopper C.G. Comparative morphologic features of bronchiolar epithelial cells. The Clara cell. Am. Rev. Respir. Dis. 1983, 128:S37-S41.
25. Plopper C.G. Clara cells. The Lung: Scientific Foundations 1990, Raven Press, New York. R.G. Crystal, J.B. West (Eds.).
26. Plopper C.G., Dungworth D.L. Structure, function, cell injury and cell renewal of bronchiolar and alveolar epithelium. Lung Carcinomas 1987, 94-128. Churchill Livingstone, London. E.M. McDowell (Ed.).
27. Plopper C.G., Mariassy A.T., Hill L.H. Ultrastructure of the nonciliated bronchiolar epithelial (Clara) cell of mammalian lung: I. A comparison of rabbit, guinea pig, rat, hamster, and mouse. Exp. Lung Res. 1980, 1:139-154.
28. Plopper C.G., Mariassy A.T., Hill L.H. Ultrastructure of the nonciliated bronchiolar epithelial (Clara) cell of mammalian lung: II. A comparison of horse, steer, sheep, dog, and cat. Exp. Lung Res. 1980, 1:155-169.
29. Plopper C.G., Halsebo J.E., Berger W.J., Sonstegard K.S., Nettesheim P. Distribution of nonciliated bronchiolar epithelial (Clara) cells in intra- and extrapulmonary airways of the rabbit. Exp. Lung Res. 1983, 5:79-98.
30. Plopper C.G., Heidsiek J.G., Weir A.J., George J.A., Hyde D.M. Tracheobronchial epithelium in the adult rhesus monkey: a quantitative histochemical and ultrastructural study. Am. J. Anat. 1989, 184:31-40.
31. Plopper C.G., Chu F.P., Haselton C.J., Peake J., Wu J., Pinkerton K.E. Dose-dependent tolerance to ozone. I. Tracheobronchial epithelial reorganization in rats after 20 months' exposure. Am. J. Pathol. 1994, 144:404-420.
32. Rodriguez M., Bur S., Favre A., Weibel E.R. Pulmonary acinus: geometry and morphometry of the peripheral airway system in rat and rabbit. Am. J. Anat. 1987, 180:143-155.
33. Shijubo N., Itoh Y., Yamaguchi T., et al. Serum and BAL Clara cell 10 kDa protein (CC10) levels and CC10-positive bronchiolar cells are decreased in smokers. Eur. Respir. J. 1997, 10:1108-1114.
34. Shijubo N., Itoh Y., Yamaguchi T., et al. Clara cell protein-positive epithelial cells are reduced in small airways of asthmatics. Am. J. Respir. Crit. Care Med. 1999, 160:930-933.
35. Sterner-Kock A., Kock M., Braun R., Hyde D.M. Ozone-induced epithelial injury in the ferret is similar to nonhuman primates. Am. J. Respir. Crit. Care Med. 2000, 162:1152-1156.
36. Tyler W.S. Comparative subgross anatomy of lungs. Pleuras, interlobular septa, and distal airways. Am. Rev. Respir. Dis. 1983, 128:S32-S36.
37. Tyler N.K., Plopper C.G. Morphology of the distal conducting airways in rhesus monkey lungs. Anat. Rec. 1985, 211:295-303.
38. Widdicombe J.G., Pack R.J. The clara cell. Eur. J. Respir. Dis. 1982, 63:202-220.
39. Winkelmann A., Noack T. The clara cell: a "Third Reich eponym"?. Eur. Respir. J. 2010, 36:722-727.
40. Young S.L., Fram E.K., Randell S.H. Quantitative three-dimensional reconstruction and carbohydrate cytochemistry of rat nonciliated bronchiolar (Clara) cells. Am. Rev. Respir. Dis. 1986, 133:899-907.