In vivo genotoxicity study of single-wall carbon nanotubes using comet assay following intratracheal instillation in rats

Regulatory Toxicology and Pharmacology

Volumn 64, Issue 1, 2012, Pages 124-129

  Naya, Masato ^a   Kobayashi, Norihiro ^a   Endoh, Shigehisa ^a   Maru, Junko ^a   Honda, Kazumasa ^a   Ema, Makoto ^a   Tanaka, Jin ^b   Fukumuro, Masahito ^b   Hasegawa, Kazushige ^b   Nakajima, Madoka ^b   Hayashi, Makoto ^b   Nakanishi, Junko ^a  

^a NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

^b Biosafety Research Center   (Japan)

Author keywords

Genotoxicity; In vivo; Nanomaterials; Single wall carbon nanotubes

Indexed keywords

DNA; MESYLIC ACID ETHYL ESTER; POLYSORBATE 80; SINGLE WALLED NANOTUBE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL INFILTRATION; COMET ASSAY; CONTROLLED STUDY; DISEASE SEVERITY; DNA DAMAGE; GENOTOXICITY; HISTOPATHOLOGY; IN VIVO STUDY; INTERMETHOD COMPARISON; LUNG ALVEOLUS EPITHELIUM; LUNG ALVEOLUS MACROPHAGE; LUNG HEMORRHAGE; MALE; NONHUMAN; OUTCOME ASSESSMENT; PNEUMONIA; PRIORITY JOURNAL; RAT; SCORING SYSTEM; WORKPLACE;

ANIMALS; COMET ASSAY; DNA DAMAGE; INHALATION EXPOSURE; INTUBATION, INTRATRACHEAL; LUNG; MALE; MUTAGENS; NANOTUBES, CARBON; PNEUMONIA; RATS; RATS, INBRED STRAINS;

RATTUS;

EID: 84864044561     PISSN: 02732300     EISSN: 10960295     Source Type: Journal    
DOI: 10.1016/j.yrtph.2012.05.020     Document Type: Article

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