Corrigendum to “MWCNTs of different physicochemical properties cause similar inflammatory responses, but differences in transcriptional and histological markers of fibrosis in mouse lungs” [Toxicol. Appl. Pharmacol., 284 (2015) 16–32] (S0041008X14004499) (10.1016/j.taap.2014.12.011));MWCNTs of different physicochemical properties cause similar inflammatory responses, but differences in transcriptional and histological markers of fibrosis in mouse lungs

Toxicology and Applied Pharmacology

Volumn 284, Issue 1, 2015, Pages 16-32

  Poulsen, Sarah S ^a,c   Saber, Anne T ^a   Williams, Andrew ^b   Andersen, Ole ^c   Købler, Carsten ^d   Atluri, Rambabu ^e   Pozzebon, Maria E ^f   Mucelli, Stefano P ^f   Simion, Monica ^g   Rickerby, David ^h   Mortensen, Alicja ^d   Jackson, Petra ^a   Kyjovska, Zdenka O ^a   Mølhave, Kristian ^d   Jacobsen, Nicklas R ^a   Jensen, Keld A ^a   Yauk, Carole L ^b   Wallin, Håkan ^a,i   Halappanavar, Sabina ^b   Vogel, Ulla ^a,d  

^a NATIONAL RESEARCH CENTRE FOR THE WORKING ENVIRONMENT   (Denmark)

^b HEALTH CANADA   (Canada)

^c ROSKILDE UNIVERSITY   (Denmark)

^d TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

^e NANOLOGICA AB   (Sweden)

^f ECSIN European Center for the Sustainable Impact of Nanotechnology   (Italy)

^g NATIONAL INSTITUTE FOR RESEARCH AND DEVELOPMENT IN MICROTECHNOLOGIES   (Romania)

^h JOINT RESEARCH CENTRE   (Italy)

ⁱ UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Acute phase response; DNA microarray; In vivo; Nanotoxicology; ROS production; Toxicogenomics

Indexed keywords

FREE RADICAL; MULTI WALLED NANOTUBE; REACTIVE OXYGEN METABOLITE; AUTACOID; CARBON NANOTUBE;

ANALYSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASSAY; BIOMICS; BRUNAUER EMMETT TELLER SURFACE AREA ANALYSIS; CELL COMPOSITION; COMET ASSAY; CONTROLLED STUDY; DICHLORODIHYDROFLUORESCEIN ASSAY; DNA DAMAGE; FEMALE; GENE EXPRESSION; GENE ONTOLOGY; GENOTOXICITY; HISTOLOGY; INFLAMMATION; INTERSTITIAL PNEUMONIA; LUNG FIBROSIS; LUNG LAVAGE; LUNG PARENCHYMA; MICROARRAY ANALYSIS; MOUSE; NANOTOXICOLOGY; NONHUMAN; PHYSICAL CHEMISTRY; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCANNING ELECTRON MICROSCOPY; SURFACE PROPERTY; THERMOGRAVIMETRY; TOXICOGENOMICS; TRANSMISSION ELECTRON MICROSCOPY; ADVERSE EFFECTS; ANIMAL; C57BL MOUSE; CHEMICALLY INDUCED; COMPARATIVE STUDY; CYTOLOGY; DOSE RESPONSE; DRUG EFFECTS; EXPOSURE; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORK; GENETIC TRANSCRIPTION; GENETICS; IMMUNOLOGY; LUNG; METABOLISM; PARTICLE SIZE; PATHOLOGY; PNEUMONIA; PROCEDURES; RISK ASSESSMENT; TIME; TOXICOGENETICS;

MUS;

ANIMALS; BRONCHOALVEOLAR LAVAGE FLUID; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORKS; INFLAMMATION MEDIATORS; INHALATION EXPOSURE; LUNG; MICE, INBRED C57BL; NANOTUBES, CARBON; PARTICLE SIZE; PNEUMONIA; PULMONARY FIBROSIS; REACTIVE OXYGEN SPECIES; RISK ASSESSMENT; SURFACE PROPERTIES; TIME FACTORS; TOXICOGENETICS; TRANSCRIPTION, GENETIC;

EID: 84923013577     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2018.06.006     Document Type: Erratum

References (88)

1. Aiso S., Yamazaki K., Umeda Y., Asakura M., Takaya M., Toya T., Koda S., Nagano K., Arito H., Fukushima S. Pulmonary toxicity of intratracheally instilled multiwall carbon nanotubes in male Fischer 344 rats. Ind. Health 2010, 48:783-795.
2. Beg S., Rizwan M., Sheikh A.M., Hasnain M.S., Anwer K., Kohli K. Advancement in carbon nanotubes: basics, biomedical applications and toxicity. J. Pharm. Pharmacol. 2011, 63:141-163.
3. Benjamini Y., Hochberg Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. J. R. Stat. Soc. Ser. B Methodol. 1995, 57:289-300.
4. Birch M.E., Ku B.K., Evans D.E., Ruda-Eberenz T.A. Exposure and emissions monitoring during carbon nanofiber production-part I: elemental carbon and iron-soot aerosols. Ann. Occup. Hyg. 2011, 55:1016-1036.
5. Bourdon J.A., Halappanavar S., Saber A.T., Jacobsen N.R., Williams A., Wallin H., Vogel U., Yauk C.L. Hepatic and pulmonary toxicogenomic profiles in mice intratracheally instilled with carbon black nanoparticles reveal pulmonary inflammation, acute phase response, and alterations in lipid homeostasis. Toxicol. Sci. 2012, 127:474-484.
6. Bourdon J.A., Saber A.T., Jacobsen N.R., Jensen K.A., Madsen A.M., Lamson J.S., Wallin H., Moller P., Loft S., Yauk C.L., Vogel U.B. Carbon black nanoparticle instillation induces sustained inflammation and genotoxicity in mouse lung and liver. Part. Fibre Toxicol. 2012, 9:5.
7. Branton M.H., Kopp J.B. TGF-beta and fibrosis. Microbes Infect. 1999, 1:1349-1365.
8. Chappell S., Daly L., Morgan K., Guetta B.T., Roca J., Rabinovich R., Millar A., Donnelly S.C., Keatings V., Macnee W., Stolk J., Hiemstra P., Miniati M., Monti S., O'Connor C.M., Kalsheker N. Cryptic haplotypes of SERPINA1 confer susceptibility to chronic obstructive pulmonary disease. Hum. Mutat. 2006, 27:103-109.
9. Chen T., Nie H., Gao X., Yang J., Pu J., Chen Z., Cui X., Wang Y., Wang H., Jia G. Epithelial-mesenchymal transition involved in pulmonary fibrosis induced by multi-walled carbon nanotubes via TGF-beta/Smad signaling pathway. Toxicol. Lett. 2014, 226:150-162.
10. Cleveland W. Robust locally weighted regression and smoothing scatterplots. J. Am. Stat. Assoc. 1979, 74:829-836.
11. Cui X., Hwang J.T., Qiu J., Blades N.J., Churchill G.A. Improved statistical tests for differential gene expression by shrinking variance components estimates. Biostatistics 2005, 6:59-75.
12. Dahl M., Tybjaerg-Hansen A., Lange P., Vestbo J., Nordestgaard B.G. Change in lung function and morbidity from chronic obstructive pulmonary disease in alpha1-antitrypsin MZ heterozygotes: a longitudinal study of the general population. Ann. Intern. Med. 2002, 136:270-279.
13. Dahm M.M., Evans D.E., Schubauer-Berigan M.K., Birch M.E., Deddens J.A. Occupational exposure assessment in carbon nanotube and nanofiber primary and secondary manufacturers: mobile direct-reading sampling. Ann. Occup. Hyg. 2013, 57:328-344.
14. Dave N.B., Kaminski N. Analysis of microarray experiments for pulmonary fibrosis. Methods Mol. Med. 2005, 117:333-358.
15. Dickson I., Alper C.A. Changes in serum proteinase inhibitor levels following bone surgery. Clin. Chim. Acta 1974, 54:381-385.
16. Donaldson K., Murphy F.A., Duffin R., Poland C.A. Asbestos, carbon nanotubes and the pleural mesothelium: a review of the hypothesis regarding the role of long fibre retention in the parietal pleura, inflammation and mesothelioma. Part. Fibre Toxicol. 2010, 7:5.
17. Driscoll K.E., Costa D.L., Hatch G., Henderson R., Oberdorster G., Salem H., Schlesinger R.B. Intratracheal instillation as an exposure technique for the evaluation of respiratory tract toxicity: uses and limitations. Toxicol. Sci. 2000, 55:24-35.
18. Erdely A., Dahm M., Chen B.T., Zeidler-Erdely P.C., Fernback J.E., Birch M.E., Evans D.E., Kashon M.L., Deddens J.A., Hulderman T., Bilgesu S.A., Battelli L., Schwegler-Berry D., Leonard H.D., McKinney W., Frazer D.G., Antonini J.M., Porter D.W., Castranova V., Schubauer-Berigan M.K. Carbon nanotube dosimetry: from workplace exposure assessment to inhalation toxicology. Part. Fibre Toxicol. 2013, 10:53.
19. Flanders K.C., Sullivan C.D., Fujii M., Sowers A., Anzano M.A., Arabshahi A., Major C., Deng C., Russo A., Mitchell J.B., Roberts A.B. Mice lacking Smad3 are protected against cutaneous injury induced by ionizing radiation. Am. J. Pathol. 2002, 160:1057-1068.
20. Grosse Y., Loomis D., Guyton K.Z., Lauby-Secretan B., Ghissassi F.E., Bouvard V., Benbrahim-Tallaa L., Guha N., Scoccianti C., Mattock H., Straif K. Carcinogenicity of fluoro-edenite, silicon carbide fibres and whiskers, and carbon nanotubes. Lancet Oncol. 2014, 15:1427-1428.
21. Halappanavar S., Jackson P., Williams A., Jensen K.A., Hougaard K.S., Vogel U., Yauk C.L., Wallin H. Pulmonary response to surface-coated nanotitanium dioxide particles includes induction of acute phase response genes, inflammatory cascades, and changes in microRNAs: a toxicogenomic study. Environ. Mol. Mutagen. 2011, 52:425-439.
22. Han J.H., Lee E.J., Lee J.H., So K.P., Lee Y.H., Bae G.N., Lee S.B., Ji J.H., Cho M.H., Yu I.J. Monitoring multiwalled carbon nanotube exposure in carbon nanotube research facility. Inhal. Toxicol. 2008, 20:741-749.
23. Hedmer M., Isaxon C., Nilsson P.T., Ludvigsson L., Messing M.E., Genberg J., Skaug V., Bohgard M., Tinnerberg H., Pagels J.H. Exposure and emission measurements during production, purification, and functionalization of arc-discharge-produced multi-walled carbon nanotubes. Ann. Occup. Hyg. 2014, 58:355-379.
24. Horvath A.J., Irving J.A., Rossjohn J., Law R.H., Bottomley S.P., Quinsey N.S., Pike R.N., Coughlin P.B., Whisstock J.C. The murine orthologue of human antichymotrypsin: a structural paradigm for clade A3 serpins. J. Biol. Chem. 2005, 280:43168-43178.
25. Huang D.W., Sherman B.T., Lempicki R.A. Systematic and integrative analysis of large gene lists using DAVID. Nucleic Acids Res. 2009, 37(1):1-13.
26. Huang D.W., Sherman B.T., Lempicki R.A. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat. Protoc. 2009, 4:44-57.
27. Husain M., Saber A.T., Guo C., Jacobsen N.R., Jensen K.A., Yauk C.L., Williams A., Vogel U., Wallin H., Halappanavar S. Pulmonary instillation of low doses of titanium dioxide nanoparticles in mice leads to particle retention and gene expression changes in the absence of inflammation. Toxicol. Appl. Pharmacol. 2013, 269:250-262.
28. Jackson P., Hougaard K.S., Boisen A.M., Jacobsen N.R., Jensen K.A., Moller P., Brunborg G., Gutzkow K.B., Andersen O., Loft S., Vogel U., Wallin H. Pulmonary exposure to carbon black by inhalation or instillation in pregnant mice: effects on liver DNA strand breaks in dams and offspring. Nanotoxicology 2011, 6:486-500.
29. Jackson P., Hougaard K.S., Vogel U., Wu D., Casavant L., Williams A., Wade M., Yauk C.L., Wallin H., Halappanavar S. Exposure of pregnant mice to carbon black by intratracheal instillation: toxicogenomic effects in dams and offspring. Mutat. Res. 2011, 745:73-83.
30. Jackson P., Pedersen L.M., Kyjovska Z.O., Jacobsen N.R., Saber A.T., Hougaard K.S., Vogel U., Wallin H. Validation of freezing tissues and cells for analysis of DNA strand break levels by comet assay. Mutagenesis 2013, 28:699-707.
31. Jackson P., Kling K., Jensen K.A., Clausen P.A., Madsen A.M., Wallin H., Vogel U. Characterization of genotoxic response to 15 multiwalled carbon nanotubes with variable physicochemical properties including surface functionalizations in the FE1-Muta(TM) mouse lung epithelial cell line. Environ. Mol. Mutagen. 2014, [Epub ahead of print]. 10.1002/em.21922.
32. Jacobsen N.R., Saber A.T., White P., Moller P., Pojana G., Vogel U., Loft S., Gingerich J., Soper L., Douglas G.R., Wallin H. Increased mutant frequency by carbon black, but not quartz, in the lacZ and cII transgenes of muta mouse lung epithelial cells. Environ. Mol. Mutagen. 2007, 48:451-461.
33. Jacobsen N.R., Pojana G., White P., Moller P., Cohn C.A., Korsholm K.S., Vogel U., Marcomini A., Loft S., Wallin H. Genotoxicity, cytotoxicity, and reactive oxygen species induced by single-walled carbon nanotubes and C(60) fullerenes in the FE1-Mutatrade markMouse lung epithelial cells. Environ. Mol. Mutagen. 2008, 49:476-487.
34. Jacobsen N.R., Moller P., Jensen K.A., Vogel U., Ladefoged O., Loft S., Wallin H. Lung inflammation and genotoxicity following pulmonary exposure to nanoparticles in ApoE-/- mice. Part. Fibre Toxicol. 2009, 6:2.
35. Jacobsen N.R., White P.A., Gingerich J., Moller P., Saber A.T., Douglas G.R., Vogel U., Wallin H. Mutation spectrum in FE1-MUTA(TM) Mouse lung epithelial cells exposed to nanoparticulate carbon black. Environ. Mol. Mutagen. 2011, 52:331-337.
36. Kasai H., Allen J.T., Mason R.M., Kamimura T., Zhang Z. TGF-beta1 induces human alveolar epithelial to mesenchymal cell transition (EMT). Respir. Res. 2005, 6:56.
37. Kerr M.K. Design considerations for efficient and effective microarray studies. Biometrics 2003, 59:822-828.
38. Kerr M.K., Churchill G.A. Statistical design and the analysis of gene expression microarray data. Genet. Res. 2007, 89:509-514.
39. Klumpp C., Kostarelos K., Prato M., Bianco A. Functionalized carbon nanotubes as emerging nanovectors for the delivery of therapeutics. Biochim. Biophys. Acta 2006, 1758:404-412.
40. Kobler C., Saber A.T., Jacobsen N.R., Wallin H., Vogel U., Qvortrup K., Molhave K. FIB-SEM imaging of carbon nanotubes in mouse lung tissue. Anal. Bioanal. Chem. 2014, 406:3863-3873.
41. Kueppers F., Fallat R., Larson R.K. Obstructive lung disease and alpha-1-antitrypsin deficiency gene heterozygosity. Science 1969, 165:899-901.
42. Leask A., Abraham D.J. TGF-beta signaling and the fibrotic response. FASEB J. 2004, 18:816-827.
43. Lee J.H., Lee S.B., Bae G.N., Jeon K.S., Yoon J.U., Ji J.H., Sung J.H., Lee B.G., Lee J.H., Yang J.S., Kim H.Y., Kang C.S., Yu I.J. Exposure assessment of carbon nanotube manufacturing workplaces. Inhal. Toxicol. 2010, 22:369-381.
44. Lee J.S., Choi Y.C., Shin J.H., Lee J.H., Lee Y., Park S.Y., Baek J.E., Park J.D., Ahn K., Yu I.J. Health surveillance study of workers who manufacture multi-walled carbon nanotubes. Nanotoxicology 2014, 1-10.
45. Linja-Aho A., Mazur W., Toljamo T., Nieminen P., Ohlmeier S., Ronty M., Kinnula V.L. Distribution and levels of alpha-1-antitrypsin in the lung and plasma in smokers and chronic obstructive pulmonary disease. APMIS 2013, 121:11-21.
46. Livak K.J., Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 2001, 25:402-408.
47. Ma-Hock L., Treumann S., Strauss V., Brill S., Luizi F., Mertler M., Wiench K., Gamer A.O., van R.B., Landsiedel R. Inhalation toxicity of multiwall carbon nanotubes in rats exposed for 3months. Toxicol. Sci. 2009, 112:468-481.
48. Mercer R.R., Hubbs A.F., Scabilloni J.F., Wang L., Battelli L.A., Friend S., Castranova V., Porter D.W. Pulmonary fibrotic response to aspiration of multi-walled carbon nanotubes. Part. Fibre Toxicol. 2011, 8:21.
49. Methner M., Hodson L., Dames A., Geraci C. Nanoparticle Emission Assessment Technique (NEAT) for the identification and measurement of potential inhalation exposure to engineered nanomaterials-part B: results from 12 field studies. J. Occup. Environ. Hyg. 2010, 7:163-176.
50. Methner M., Beaucham C., Crawford C., Hodson L., Geraci C. Field application of the Nanoparticle Emission Assessment Technique (NEAT): task-based air monitoring during the processing of engineered nanomaterials (ENM) at four facilities. J. Occup. Environ. Hyg. 2012, 9:543-555.
51. Moeller A., Rodriguez-Lecompte J.C., Wang L., Gauldie J., Kolb M. Models of pulmonary fibrosis. Drug Discov. Today 2006, 3:243-249.
52. Moeller A., Ask K., Warburton D., Gauldie J., Kolb M. The bleomycin animal model: a useful tool to investigate treatment options for idiopathic pulmonary fibrosis?. Int. J. Biochem. Cell Biol. 2008, 40:362-382.
53. Muller J., Huaux F., Moreau N., Misson P., Heilier J.F., Delos M., Arras M., Fonseca A., Nagy J.B., Lison D. Respiratory toxicity of multi-wall carbon nanotubes. Toxicol. Appl. Pharmacol. 2005, 207:221-231.
54. Murphy F.A., Poland C.A., Duffin R., Al-Jamal K.T., li-Boucetta H., Nunes A., Byrne F., Prina-Mello A., Volkov Y., Li S., Mather S.J., Bianco A., Prato M., Macnee W., Wallace W.A., Kostarelos K., Donaldson K. Length-dependent retention of carbon nanotubes in the pleural space of mice initiates sustained inflammation and progressive fibrosis on the parietal pleura. Am. J. Pathol. 2011, 178:2587-2600.
55. Olsen G.N., Harris J.O., Castle J.R., Waldman R.H., Karmgard H.J. Alpha-1-antitrypsin content in the serum, alveolar macrophages, and alveolar lavage fluid of smoking and nonsmoking normal subjects. J. Clin. Invest. 1975, 55:427-430.
56. Pantazopoulos I., Xanthos T., Boura P., Syrigos K. Mesothelin and osteopontin. Eur. Respir. J. 2013, 42:557-558.
57. Park E.J., Cho W.S., Jeong J., Yi J., Choi K., Park K. Pro-inflammatory and potential allergic responses resulting from B cell activation in mice treated with multi-walled carbon nanotubes by intratracheal instillation. Toxicology 2009, 259:113-121.
58. Pass H.I., Lott D., Lonardo F., Harbut M., Liu Z., Tang N., Carbone M., Webb C., Wali A. Asbestos exposure, pleural mesothelioma, and serum osteopontin levels. N. Engl. J. Med. 2005, 353:1564-1573.
59. Pauluhn J. Multi-walled carbon nanotubes (Baytubes): approach for derivation of occupational exposure limit. Regul. Toxicol. Pharmacol. 2010, 57:78-89.
60. Pauluhn J. Subchronic 13-week inhalation exposure of rats to multiwalled carbon nanotubes: toxic effects are determined by density of agglomerate structures, not fibrillar structures. Toxicol. Sci. 2010, 113:226-242.
61. Peng R., Sridhar S., Tyagi G., Phillips J.E., Garrido R., Harris P., Burns L., Renteria L., Woods J., Chen L., Allard J., Ravindran P., Bitter H., Liang Z., Hogaboam C.M., Kitson C., Budd D.C., Fine J.S., Bauer C.M., Stevenson C.S. Bleomycin induces molecular changes directly relevant to idiopathic pulmonary fibrosis: a model for "active" disease. PLoS One 2013, 8:e59348.
62. Poland C.A., Duffin R., Kinloch I., Maynard A., Wallace W.A., Seaton A., Stone V., Brown S., Macnee W., Donaldson K. Carbon nanotubes introduced into the abdominal cavity of mice show asbestos-like pathogenicity in a pilot study. Nat. Nanotechnol. 2008, 3:423-428.
63. Porter D.W., Hubbs A.F., Mercer R.R., Wu N., Wolfarth M.G., Sriram K., Leonard S., Battelli L., Schwegler-Berry D., Friend S., Andrew M., Chen B.T., Tsuruoka S., Endo M., Castranova V. Mouse pulmonary dose- and time course-responses induced by exposure to multi-walled carbon nanotubes. Toxicology 2010, 269:136-147.
64. Poulsen S.S., Jacobsen N.R., Labib S., Wu D., Husain M., Williams A., Bogelund J.P., Andersen O., Kobler C., Molhave K., Kyjovska Z.O., Saber A.T., Wallin H., Yauk C.L., Vogel U., Halappanavar S. Transcriptomic analysis reveals novel mechanistic insight into murine biological responses to multi-walled carbon nanotubes in lungs and cultured lung epithelial cells. PLoS One 2013, 8:e80452.
65. Ravichandran P., Baluchamy S., Gopikrishnan R., Biradar S., Ramesh V., Goornavar V., Thomas R., Wilson B.L., Jeffers R., Hall J.C., Ramesh G.T. Pulmonary biocompatibility assessment of inhaled single-wall and multiwall carbon nanotubes in BALB/c mice. J. Biol. Chem. 2011, 286:29725-29733.
66. Reddy A.R., Reddy Y.N., Krishna D.R., Himabindu V. Pulmonary toxicity assessment of multiwalled carbon nanotubes in rats following intratracheal instillation. Environ. Toxicol. 2010, 27:211-219.
67. Rittinghausen S., Hackbarth A., Creutzenberg O., Ernst H., Heinrich U., Leonhardt A., Schaudien D. The carcinogenic effect of various multi-walled carbon nanotubes (MWCNTs) after intraperitoneal injection in rats. Part. Fibre Toxicol. 2014, 11:59.
68. Rodriguez Portal J.A. Asbestos-related disease: screening and diagnosis. Adv. Clin. Chem. 2012, 57:163-185.
69. Ronzani C., Spiegelhalter C., Vonesch J.L., Lebeau L., Pons F. Lung deposition and toxicological responses evoked by multi-walled carbon nanotubes dispersed in a synthetic lung surfactant in the mouse. Arch. Toxicol. 2012, 86:137-149.
70. Ryman-Rasmussen J.P., Tewksbury E.W., Moss O.R., Cesta M.F., Wong B.A., Bonner J.C. Inhaled multiwalled carbon nanotubes potentiate airway fibrosis in murine allergic asthma. Am. J. Respir. Cell Mol. Biol. 2009, 40:349-358.
71. Saber A.T., Jacobsen N.R., Mortensen A., Szarek J., Jackson P., Madsen A.M., Jensen K.A., Koponen I.K., Brunborg G., Gutzkow K.B., Vogel U., Wallin H. Nanotitanium dioxide toxicity in mouse lung is reduced in sanding dust from paint. Part. Fibre Toxicol. 2012, 9:4.
72. Saber A.T., Lamson J.S., Jacobsen N.R., Ravn-Haren G., Hougaard K.S., Nyendi A.N., Wahlberg P., Madsen A.M., Jackson P., Wallin H., Vogel U. Particle-induced pulmonary acute phase response correlates with neutrophil influx linking inhaled particles and cardiovascular risk. PLoS One 2013, 8:e69020.
73. Sato M., Muragaki Y., Saika S., Roberts A.B., Ooshima A. Targeted disruption of TGF-beta1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction. J. Clin. Invest. 2003, 112:1486-1494.
74. Shvedova A.A., Kisin E., Murray A.R., Johnson V.J., Gorelik O., Arepalli S., Hubbs A.F., Mercer R.R., Keohavong P., Sussman N., Jin J., Yin J., Stone S., Chen B.T., Deye G., Maynard A., Castranova V., Baron P.A., Kagan V.E. Inhalation vs. aspiration of single-walled carbon nanotubes in C57BL/6 mice: inflammation, fibrosis, oxidative stress, and mutagenesis. Am. J. Physiol. Lung Cell. Mol. Physiol. 2008, 295:L552-L565.
75. Silverman G.A., Bird P.I., Carrell R.W., Church F.C., Coughlin P.B., Gettins P.G., Irving J.A., Lomas D.A., Luke C.J., Moyer R.W., Pemberton P.A., Remold-O'Donnell E., Salvesen G.S., Travis J., Whisstock J.C. The serpins are an expanding superfamily of structurally similar but functionally diverse proteins. Evolution, mechanism of inhibition, novel functions, and a revised nomenclature. J. Biol. Chem. 2001, 276:33293-33296.
76. Snyder-Talkington B.N., Dymacek J., Porter D.W., Wolfarth M.G., Mercer R.R., Pacurari M., Denvir J., Castranova V., Qian Y., Guo N.L. System-based identification of toxicity pathways associated with multi-walled carbon nanotube-induced pathological responses. Toxicol. Appl. Pharmacol. 2013, 272:476-489.
77. Stein P.E., Carrell R.W. What do dysfunctional serpins tell us about molecular mobility and disease?. Nat. Struct. Biol. 1995, 2:96-113.
78. Strieter R.M., Mehrad B. New mechanisms of pulmonary fibrosis. Chest 2009, 136:1364-1370.
79. The Nanogentox group Nanogenotox (2013) Facilitating the Safety Evaluation of Manufactured Nanomaterials By Characterising Their Potential Genotoxicity Hazard 2013.
80. Travis J., Bowen J., Baugh R. Human alpha-1-antichymotrypsin: interaction with chymotrypsin-like proteinases. Biochemistry 1978, 17:5651-5656.
81. Wang X., Katwa P., Podila R., Chen P., Ke P.C., Rao A.M., Walters D.M., Wingard C.J., Brown J.M. Multi-walled carbon nanotube instillation impairs pulmonary function in C57BL/6 mice. Part. Fibre Toxicol. 2011, 8:24.
82. Wang X., Xia T., Ntim S.A., Ji Z., Lin S., Meng H., Chung C.H., George S., Zhang H., Wang M., Li N., Yang Y., Castranova V., Mitra S., Bonner J.C., Nel A.E. Dispersal state of multiwalled carbon nanotubes elicits profibrogenic cellular responses that correlate with fibrogenesis biomarkers and fibrosis in the murine lung. ACS Nano 2011, 5:9772-9787.
83. Wang P., Nie X., Wang Y., Li Y., Ge C., Zhang L., Wang L., Bai R., Chen Z., Zhao Y., Chen C. Multiwall carbon nanotubes mediate macrophage activation and promote pulmonary fibrosis through TGF-beta/Smad signaling pathway. Small 2013, 9:3799-3811.
84. Wang P., Wang Y., Nie X., Braini C., Bai R., Chen C. Multiwall carbon nanotubes directly promote fibroblast-myofibroblast and epithelial-mesenchymal transitions through the activation of the TGF-beta/Smad signaling pathway. Small 2014, [Epub ahead of print]. 10.1002/smll.201303588.
85. Willis B.C., Borok Z. TGF-beta-induced EMT: mechanisms and implications for fibrotic lung disease. Am. J. Physiol. Lung Cell. Mol. Physiol. 2007, 293:L525-L534.
86. Willis B.C., Liebler J.M., Luby-Phelps K., Nicholson A.G., Crandall E.D., du Bois R.M., Borok Z. Induction of epithelial-mesenchymal transition in alveolar epithelial cells by transforming growth factor-beta1: potential role in idiopathic pulmonary fibrosis. Am. J. Pathol. 2005, 166:1321-1332.
87. Wu H., Kerr M.K., Cui X., Churchill G.A. MAANOVA: a software package for the analysis of spotted cDNA microarray experiments. The Analysis of Gene Expression Data: Methods and Software 2003, 313-341. Springer. G. Parmigiani (Ed.).
88. Yamashita K., Yoshioka Y., Higashisaka K., Morishita Y., Yoshida T., Fujimura M., Kayamuro H., Nabeshi H., Yamashita T., Nagano K., Abe Y., Kamada H., Kawai Y., Mayumi T., Yoshikawa T., Itoh N., Tsunoda S., Tsutsumi Y. Carbon nanotubes elicit DNA damage and inflammatory response relative to their size and shape. Inflammation 2010, 33:276-280.