Thickness of multiwalled carbon nanotubes affects their lung toxicity

Chemical Research in Toxicology

Volumn 25, Issue 1, 2012, Pages 74-82

  Fenoglio, Ivana ^a   Aldieri, Elisabetta ^a   Gazzano, Elena ^a   Cesano, Federico ^a   Colonna, Massimiliano ^a   Scarano, Domenica ^a   Mazzucco, Gianna ^a   Attanasio, Angelo ^a   Yakoub, Yousof ^b   Lison, Dominique ^b   Fubini, Bice ^a  

^a UNIVERSITY OF TURIN   (Italy)

^b UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTATHIONE; LACTATE DEHYDROGENASE; MULTI WALLED NANOTUBE; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ARTICLE; CYTOTOXICITY; HYDROPHOBICITY; LUNG ALVEOLUS MACROPHAGE; LUNG LAVAGE; LUNG TOXICITY; MOUSE; NONHUMAN; OXIDATIVE STRESS; THICKNESS;

ANIMALS; BIOLOGICAL TRANSPORT; BRONCHOALVEOLAR LAVAGE FLUID; CELL COUNT; FEMALE; GLUTATHIONE; L-LACTATE DEHYDROGENASE; LUNG; MACROPHAGES, ALVEOLAR; MICE; MICROSCOPY, ELECTRON, TRANSMISSION; NANOTUBES, CARBON; PARTICLE SIZE; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; SPECTRUM ANALYSIS, RAMAN; SURFACE PROPERTIES;

MURINAE; RATTUS;

EID: 84855841413     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/tx200255h     Document Type: Article

References (63)

1. Endo, M., Strano, M. S., and Ajayan, P. M. (2008) Potential applications of carbon nanotubes Top. Appl. Phys. 111, 13-62
2. Lee, J., Mahendra, S., and Alvarez, P. J. J. (2010) Nanomaterials in the construction industry: a review of their applications and environmental health and safety considerations ACS Nano 4, 3580-3590
3. Liu, Z., Tabakman, S., Welsher, K., and Dai, H. (2009) Carbon nanotubes in biology and medicine: in vitro and in vivo detection, imaging and drug delivery Nano Res. 2, 85-120
4. Zhang, Y., Bai, Y., and Yan, B. (2010) Functionalized carbon nanotubes for potential medicinal applications Drug Discovery Today 15, 429-435
5. Donaldson, K., Aitken, R., Tran, L., Stone, V., Duffin, R., Forrest, G., and Alexander, A. (2006) Carbon nanotubes: A review of their properties in relation to pulmonary toxicology and workplace safety Toxicol. Sci. 92, 5-22 (Pubitemid 43985785)
6. Warheit, D. B. (2006) What is currently known about the health risks related to carbon nanotube exposures? Carbon 44, 1064-1069 (Pubitemid 43202163)
7. Kane, A. B. and Hurt, R. H. (2008) Nanotoxicology: The asbestos analogy revisited Nature Nanotechnol. 3, 378-379 (Pubitemid 351948250)
8. Kostarelos, K. (2008) The long and short of carbon nanotube toxicity Nat. Biotechnol. 26, 774-776 (Pubitemid 351961446)
9. Lison, D. and Muller, J. (2008) Toxicol. Sci. 101, 179-180
10. Sanchez, V. C., Pietruska, J. R., Miselis, N. R., Hurt, R. H., and Kane, A. B. (2009) Biopersistence and potential adverse health impacts of fibrous nanomaterials: what have we learned from asbestos? Wiley Interdiscip. Rev., Nanomed. Nanobiotechnol. 1, 511-529
11. Shvedova, A. A., Kisin, E. R., Porter, D., Schulte, P., Kagan, V. E., Fadeel, B., and Castranova, V. (2009) Mechanisms of pulmonary toxicity and medical applications of carbon nanotubes: Two faces of Janus? Pharmacol. Ther. 121, 192-204
12. Shvedova, A. A. and Kagan, V. E. (2010) The role of nanotoxicology in realizing the 'helping without harm' paradigm of nanomedicine: lessons from studies of pulmonary effects of single-walled carbon nanotubes J. Intern. Med. 267, 106-118
13. Pacurari, M., Castranova, V., and Vallyathan, V. (2010) Single- and multi-wall carbon nanotubes versus asbestos: are the carbon nanotubes a new health risk to humans? J. Toxicol. Environ. Health 73, 378-395
14. Service, R. F. (1998) Nanotubes: the next asbestos? Science 281, 841-847
15. Turci, F., Tomatis, M., Lesci, I. G., Roveri, N., and Fubini, B. (2011) The iron-related molecular toxicity mechanism of synthetic asbestos nanofibres: a model study for high-aspect-ratio nanoparticles Chem.-Eur. J. 17, 350-358
16. Fenoglio, I., Tomatis, M., Lison, D., Muller, J., Fonseca, A., Nagy, J. B., and Fubini, B. (2006) Reactivity of carbon nanotubes: Free radical generation or scavenging activity? Free Radical Biol. Med. 40, 1227-1233
17. Fenoglio, I., Greco, G., Tomatis, M., Muller, J., Raymundo-Pinero, E., Beguin, F., Fonseca, A., Nagy, J. B., Lison, D., and Fubini, B. (2008) Structural defects play a major role in the acute lung toxicity of multiwall carbon nanotubes: Physicochemical aspects Chem. Res. Toxicol. 21, 1690-1697
18. Galano, A., Francisco-Marquez, M., and Martinez, A. (2010) Influence of point defects on the free-radical scavenging capability of single-walled carbon nanotubes J. Phys. Chem. C 114, 8302-8308
19. Meng, H., Xia, T., George, S., and Nel, A. E. (2009) A predictive toxicological paradigm for the safety assessment of nanomaterials ACS Nano 3, 1620-1627
20. Rivera Gil, P., Oberdörster, G., Elder, A., Puntes, V., and Parak, W. J. (2010) Correlating physico-chemical with toxicological properties of nanoparticles: the present and the future ACS Nano 4, 5527-5521
21. Charlier, J. C. (2002) Defects in carbon nanotubes Acc. Chem. Res. 35, 1063-1069
22. Warheit, D. B., Laurence, B. R., Reed, K. L., Roach, D. H., Reynolds, G. A. M., and Webb, T. R. (2004) Comparative pulmonary toxicity assessment of single-wall carbon nanotubes in rats Toxicol. Sci. 77, 117-125 (Pubitemid 38128651)
23. Shvedova, A., Kisin, E. R., Mercer, R., Murray, A. R., Johnson, V. J., Potapovich, A. I., Tyurina, Y. Y., Gorelick, O., Arepalli, S., Schwegler-Berry, D., Hubbs, A. F., Antonini, J., Evans, D. E., Ku, B. K., Ramsey, D., Maynard, A., Kagan, V. E., Castranova, V., and Baron, P. (2005) Unusual inflammatory and fibrogenic pulmonary responses to single walled carbon nanotubes in mice Am. J. Physiol. Lung Cell. Mol. Physiol. 289, L698-L708
24. Muller, J., Huaux, F., Moreau, N., Misson, P., Heilier, J. F., Delos, M., Arras, M., Fonseca, A., Nagy, J. B., and Lison, D. (2005) Respiratory toxicity of multi-wall carbon nanotubes Toxicol. Appl. Pharmacol. 207, 221-231 (Pubitemid 41207915)
25. Kagan, V. E., Tyurina, Y. Y., Tyurin, V. A., Konduru, N. V., and Potapovich, A. I. (2006) Direct and indirect effects of single walled carbon nanotubes on RAW 264.7 macrophages: Role of iron Toxicol. Lett. 165, 88-100 (Pubitemid 43867182)
26. Ma-Hock, L., Treumann, S., Strauss, V., Brill, S., Luizi, F., Mertler, M., Wiench, K., Gamer, A. O., van Ravenzwaay, B., and Landsiedel, R. (2009) Inhalation toxicity of multiwall carbon nanotubes in rats exposed for 3 months Toxicol. Sci. 112, 468-481
27. Mitchell, L. A., Gao, J., Wal, R. V., Gigliotti, A., Burchiel, S. W., and McDonald, J. D. (2007) Pulmonary and systemic immune response to inhaled multiwalled carbon nanotubes Toxicol. Sci. 100, 203-214 (Pubitemid 47617817)
28. Elgrabli, D., Abella-Gallart, S., Robidel, F., Rogerieux, F., Boczkowski, J., and Lacroix, G. (2008) Effect of BSA on carbon nanotube dispersion for in vivo and in vitro studies Toxicology 253, 131-136
29. Takagi, A., Hirose, A, Nishimura, T., Fukumori, N., Ogata, A., Ohashi, N., Kitajima, S., and Kanno, L. (2008) Induction of mesothelioma in p53± mouse by intraperitoneal application of multi-wall carbon nanotubes J. Toxicol. Sci. 33, 105-116 (Pubitemid 351340768)
30. Sakamoto, Y., Nakae, D., Fukumori, N., Tayama, K., Maekawa, A., Imai, K., Hirose, A., Nishimura, T., Ohashi, N., and Ogata, A. (2009) Induction of mesothelioma by a single intrascrotal administration of multi-wall carbon nanotube in intact male Fischer 344 rats J. Toxicol. Sci. 34, 65-76
31. Muller, J., Delos, M., Panin, N., Rabolli, V., Huaux, F., and Lison, D. (2009) Absence of carcinogenic response to multi-wall carbon nanotubes in a 2-year bioassay in the peritoneal cavity of the rat: quenching radicals Toxicol. Sci. 110, 442-448
32. Poland, A., Duffin, R., Kinloch, I., Maynard, A., Wallace, W. A. H., Seaton, A., Stone, V., Brown, S., MacNee, W., and Donaldson, K. (2008) Carbon nanotubes introduced into the abdominal cavity of mice show asbestoslike pathogenicity in a pilot study Nature Nanotechnol. 3, 423-428
33. Kolosnjaj-Tabi, J., Hartman, K. B., Boudjemaa, S., Ananta, J. S., Morgant, G., Szwarc, H., Wilson, L. J., and Moussa, F. (2010) In vivo behavior of large doses of ultrashort and full-length single-walled carbon nanotubes after oral and intraperitoneal administration to Swiss mice ACS Nano 4, 1481-1492
34. Donaldson, K., Murphy, F., Schinwald, A., Duffin, R., and Poland, C. A. (2011) Identifying the pulmonary hazard of high aspect ratio nanoparticles to enable their safety-by-design Nanomedicine 6, 143-156
35. Pulskamp, K., Diabate, S., and Krug, H. F. (2007) Carbon nanotubes show no sign of acute toxicity but induce intracellular reactive oxygenspecies in dependence on contaminants Toxicol. Lett. 168, 58-74 (Pubitemid 44909723)
36. Bottini, M., Bruckner, S., Nika, K., Bottini, N., Bellocci, S., Magrini, A., Bergamaschi, A., and Mustelin, T. (2006) Multi-walled carbon nanotubes induce T lymphocyte apoptosis Toxicol. Lett. 160, 121-126 (Pubitemid 41578955)
37. Vittorio, O., Raffa, V., and Cuschieri, A. (2009) Influence of purity and surface oxidation on cytotoxicity of multiwalled carbon nanotubes with human neuroblastoma cells Nanomedicine 5, 424-43
38. Muller, J., Huaux, F., Fonseca, A., Nagy, J. B., Moreau, N., Delos, M., Raymundo-Piñero, E., Béguin, F., Kirsch-Volders, M., Fenoglio, I., Fubini, B., and Lison, D. (2008) Structural defects play a major role in the acute lung toxicity of multiwall carbon nanotubes: toxicological aspects Chem. Res. Toxicol. 21, 1698-1705
39. Wang, X., Jia, G., Wang, H., Nie, H., Yan, L., Deng, X. Y., and Wang, S. (2009) Diameter effects on cytotoxicity of multi-walled carbon nanotubes J. Nanosci. Nanotechnol. 9, 3025-3033
40. Yamashita, K., Yoshioka, Y., Higashisaka, K., Morishita, Y., Yoshida, T., Fujimura, M., Kayamuro, H., Nabeshi, H., Yamashita, T., Nagano, K., Abe, Y., Kamada, H., Kawai, Y., Mayumi, T., Yoshikawa, T., Itoh, N., Tsunoda, S., and Tsutsumi, Y. (2010) Carbon nanotubes elicit DNA damage and inflammatory response relative to their size and shape Inflammation 33, 276-280
41. Willems, I., Konya, Z., Colomer, J. F., Van Tendeloo, G., Nagajaru, N., Fonseca, A., and Nagy, J. B. (2000) Control of the outer diameter of thin carbon nanotubes synthesized by catalytic decomposition of hydrocarbons Chem. Phys. Lett. 317, 71-76
42. Kinnula, V. L., Aalto, K., Raivio, K. O., Walles, S., and Linnainmaa, K. (1994) Cytotoxicity of oxidants and asbestos fibers in cultured human mesothelial cells Free Radical Biol. Med. 16, 169-176 (Pubitemid 24117497)
43. Riganti, C., Aldieri, E., Bergandi, L., Fenoglio, I., Costamagna, C., Fubini, B., Bosia, A., and Ghigo, D. (2002) Crocidolite asbestos inhibits pentose phosphate oxidative pathway and glucose 6-phosphate dehydrogenase activity in human lung epithelial cells Free Radical Biol. Med. 32, 938-949 (Pubitemid 34439265)
44. Vandeputte, C., Guizon, I., Genestie-Denis, I., Vannier, B., and Lorenzon, G. (1994) A microtiter plate assay for total glutathione and glutathione disulfide contents in cultured/isolated cells-performance study of a new miniaturized protocol Cell. Biol. Toxicol. 10, 415-421 (Pubitemid 24377319)
45. Jorio, A., Saito, R., Dresselhaus, G., and Dresselhaus, M. S. (2004) Determination of nanotubes properties by Raman spectroscopy Philos. Trans. R. Soc., A 362, 2311-2336 (Pubitemid 39518771)
46. Osswald, S., Havel, M., and Gogotsi, Y. (2007) Monitoring oxidation of multiwalled carbon nanotubes by Raman spectroscopy J. Raman Spectrosc. 38, 728-736
47. Fubini, B., Bolis, V., Cavenago, A., Garrone, E., and Ugliengo, P. (1993) Structural and induced heterogeneity at the surface of some sio2 polymorphs from the enthalpy of adsorption of various molecules Langmuir 9, 2712-2721
48. Raffa, V., Ciofani, G., Vittorio, O., Riggio, C., and Cuschieri, A. (2010) Physicochemical properties affecting cellular uptake of carbon nanotubes Nanomedicine 5, 89-97
49. Raja, P. M. V., Connolley, J., Ganesan, G. P., Ci, L., Ajayan, P. M., Nalamasu, O., and Thompson, D. M. (2007) Impact of carbon nanotube exposure, dosage and aggregation on smooth muscle cells Toxicol. Lett. 169, 51-63 (Pubitemid 46215955)
50. Wick, P., Manser, P., Limbach, L. K., Dettlaff-Weglikowsk, U., Krumeich, F., Roth, S., Stark, W. J., and Bruinink, A. (2007) The degree and kind of agglomeration affect carbon nanotube cytotoxicity Toxicol. Lett. 168, 121-131 (Pubitemid 46054362)
51. Wang, L., Mercer, R. R., Rojanasakul, Y., Qiu, A., Lu, Y., Scabilloni, J. F., Wu, N., and Castranova, V. (2010) Direct fibrogenic effects of dispersed single-walled carbon nanotubes on human lung fibroblasts J. Toxicol. Environ. Health, Part A 73, 410-422
52. Mercer, R. R., Scabilloni, J., Wang, L., Kisin, E., Murray, A. R., Schwegler-Berry, D., Shvedova, A. A., and Castranova, V. (2008) Alteration of deposition pattern and pulmonary response as a results of improved dispersion of aspirated single walled carbon nanotubes in a mousemodel Am. J. Physiol. Lung Cell Mol. Physiol. 294, L87-L97
53. Porter, D. W., Hubbs, A. F., Mercer, R. R., Wu, N., Wolfarth, M. G., Sriram, K., Leonard, S. S., Batelli, L., Schwegler- Berry, D., Friend, S., Andrew, M., Chen, B. T., Tsuruok, S., Endo, M., and Castranova, V. (2010) Mouse pulmonary doseand time course-response induced by exposure to multi-walled carbon nanotubes Toxicology 269, 136-147
54. Pauluhn, J. (2010) Subchronic 13-week inhalation exposure of rats to multiwalled carbon nanotubes: toxic effects are determined by density of agglomerate structures, not fibrillar structure Toxicol. Sci. 113, 226-242
55. Peigney, A., Laurent, C., Flahaut, E., Bacsa, R. R., and Rousset, A. (2001) Specific surface area of carbon nanotubes and bundles of carbon nanotubes Carbon 39, 507-514 (Pubitemid 32263502)
56. Fubini, B., Ghiazza, M., and Fenoglio, I. (2010) Nanotoxicology 4, 347-363
57. Lundqvist, M., Sethson, I., and Jonsson, B. H. (2004) Protein adsorption onto silica nanoparticles: Conformational changes depend on the particles' curvature and the protein stability Langmuir 20, 10639-10647
58. Karajanagi, S. S., Vertegel, A. A., Kane, R. S., and Dordick, J. S. (2004) Structure and function of enzymes adsorbed onto single-walled carbon nanotubes Langmuir 20, 11594-11599 (Pubitemid 40049633)
59. Lynch, I. and Dawson, K. A. (2008) Protein-nanoparticle interactions Nano Today 3, 40-47 (Pubitemid 351298587)
60. Salvador-Morales, C., Townsend, P., Flahaut, E., Venien-Bryan, C., Vlandas, A., Green, M. L. H., and Sim, R. B. (2007) Binding of pulmonary surfactant proteins to carbon nanotubes; potential for damage to lung immune defense mechanisms Carbon 45, 607-617 (Pubitemid 46148826)
61. Dutta, D., Sundaram, S. K., Teeguarden, J. G., Riley, B. J., Fifield, L. S., Jacobs, J. M., Addleman, S. R., Kaysen, G. A., Moudgil, B. M., and Weber, T. J. (2007) Adsorbed proteins influence the biological activity and molecular targeting of nanomaterials Toxicol. Sci. 100, 303-315 (Pubitemid 47617826)
62. Lord, M. S., Cousins, B. G., Doherty, P. J., Whitelock, J. M., Simmons, A., Williams, R. L., and Milthorpe, B. K. (2006) The effect of silica nanoparticulate coatings on serum protein adsorption and cellular response Biomaterials 27, 4856-4862 (Pubitemid 43866929)
63. Horie, M., Nishio, K., Fujita, K., Endoh, S., Miyauchi, A., Saito, Y., Iwahashi, H., Yamamoto, K., Murayama, H., Nakano, H., Nanashima, N., Niki, E., and Yoshida, Y. (2009) Protein adsorption of ultrafine metal oxide and its influence on cytotoxicity toward cultured cells Chem. Res. Toxicol. 22, 543-553