Unusual inflammatory and fibrogenic pulmonary responses to single-walled carbon nanotubes in mice

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 289, Issue 5 33-5, 2005, Pages

  Shvedova, Anna A ^a   Kisin, Elena R ^a   Mercer, Robert ^a   Murray, Ashley R ^a   Johnson, Victor J ^a   Potapovich, Alla I ^c   Tyurina, Yulia Y ^c   Gorelik, Olga ^b   Arepalli, Sevaram ^b   Schwegler Berry, Diane ^a   Hubbs, Ann F ^a   Antonini, James ^a   Evans, Douglas E ^a   Ku, Bon Ki ^a   Ramsey, Dawn ^a   Maynard, Andrew ^a   Kagan, Valerian E ^c   Castranova, Vincent ^a,c   Baron, Paul ^a  

^a NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTH   (United States)

^b NASA JOHNSON SPACE CENTER   (United States)

^c UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

Cytokines; Inflammation; Microbial infection; Nanoparticles

Indexed keywords

4 HYDROXYNONENAL; BIOLOGICAL MARKER; CARBON; CARBON NANOTUBE; CYTOKINE; GAMMA GLUTAMYLTRANSFERASE; GLUTATHIONE; INTERLEUKIN 1BETA; LACTATE DEHYDROGENASE; NANOPARTICLE; NITRIC OXIDE; SILICON DIOXIDE; SUPEROXIDE; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA; ZYMOSAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ASPIRATION; BIOACCUMULATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE COURSE; ENZYME ACTIVITY; EXPOSURE; FEMALE; FIBROSING ALVEOLITIS; IN VITRO STUDY; LISTERIA MONOCYTOGENES; LUNG ALVEOLUS EPITHELIUM; LUNG ALVEOLUS WALL; LUNG FIBROSIS; LUNG GRANULOMA; LUNG INJURY; LUNG LAVAGE; LYMPHOCYTE; MACROPHAGE; MATERIALS; MORPHOLOGY; MOUSE; NEUTROPHIL; NONHUMAN; OXIDATION; PHARYNX; PRIORITY JOURNAL; RESPIRATORY TRACT INFLAMMATION; TECHNOLOGY; THICKNESS;

ANIMALS; BRONCHOALVEOLAR LAVAGE FLUID; CELL LINE; CYTOKINES; FEMALE; GAMMA-GLUTAMYLTRANSFERASE; GLUTATHIONE; GRANULOMA, FOREIGN-BODY; INFLAMMATION; INFLAMMATION MEDIATORS; L-LACTATE DEHYDROGENASE; LUNG; LUNG DISEASES; MICE; MICE, INBRED C57BL; NANOTUBES, CARBON; PNEUMONIA; PULMONARY FIBROSIS;

EID: 24944566939     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.00084.2005     Document Type: Article

References (29)

1. Adelman P, Baierl T, Drosselmeyer E, Politis C, Polzer G, Seidel A, and Steinleitner C. Effect of fullerenes on alveolar macrophages in vitro. Institut für Nukleare Festkörperphysik, Karlsruhe, Germany. In: Toxic and Carcinogenic Effect of Solid Particles in the Respiratory Tract, edited by Mohr U, Dungworth DL, Mauderly J, Oberdoester G. Washington, DC: ILSI Press, 1994, p. 405-407.
2. Adler A, Cieslewicz G, and Irvin CG. Unrestrained plethysmography is an unreliable measure of airway responsiveness in BALB/c and C57BL/6 mice. J Appl Physiol 97: 286-292, 2004.
3. Arepalli S, Nikolaev P, and Gorelik O. Protocol for the characterization of SWCNT material quality. Carbon 42: 1783-1791, 2004.
4. Arepalli S, Nikolaev P, and Gorelik O. Analytical characterization of single wall carbon nanotubes. In: Encyclopedia of Nanoscience and Nanotechnology, 2004, vol. 1, p. 51-66.
5. Birch ME. Elemental carbon monitoring of diesel exhaust particulate in the workplace. In: NIOSH Manual of Analytical Methods (NMAM 5040) (4th ed.). Cincinnati. OH: NIOSH, 2003, chapt. Q (DHHS publication no. 2003-154).
6. Bronikowski MJ, Willis PA, Colbert DT, Smith KA, and Smalley RE. Gas-phase production of carbon single-walled nanotubes from carbon monoxide via the HiPco process: a parametric study. J Vac Sci Technol 19: 1800-1805, 2001.
7. Cherukur P, Bachilo SM, Litovsky SH, and Weisman RB. Near-infrared fluorescence microscopy of single-walled carbon nanotubes in phagocytic cells. J Am Chem Soc 126: 15638-15639, 2004.
8. Dresselhaus MS, Dresselhaus G, Charlier JC, and Hernandez E. Electronic, thermal and mechanical properties of carbon nanotubes. Philos Transact Ser A Math Phys Eng Sci 362: 2065-2098, 2004.
9. Driscoll KE, Costa DL, Hatch G, Henderson R, Oberdorster G, Salem H, and Schlesinger RB. Intratracheal instillation as an exposure technique for the evaluation of respiratory tract toxicity: uses and limitations. Toxicol Sci 55: 24-35, 2000.
10. Elder AC, Gelein R, Azadniv M, Frampton M, Finkelstein J, and Oberdorster G. Systemic effects of inhaled ultrafine particles in two compromised, aged rat strains. Inhal Toxicol 16: 461-471, 2004.
11. Ghanem MM, Porter D, Battelli LA, Vallyathan V, Kashon ML, Ma JY, Barger MW, Nath J, Castranova V, and Hubbs AF. Respirable coal dust particles modify cytochrome P4501A1 (CYP1A1) expression in rat alveolar cells. Am J Respir Cell Mol Biol 31: 171-183, 2004.
12. Gorelik O, Nikolaev P, and Arepalli S. Purification Procedures for Single-Walled Carbon Nanotubes. NASA Contractor Report. Hanover, MD: NASA, 2000 (NASA/CR-2000-208926).
13. Henderson RF, Driscoll KE, Harkema JR, Lindenschmidt RC, Chang IY, Maples KR, and Barr EB. A comparison of the inflammatory response of the lung to inhaled versus instilled particles in F344 rats. Fundam Appl Toxicol 24: 183-197, 1995.
14. Huzcko A, Lange H, Calko E, Grubek-Jaworska H, and Droszcz P. Physiological testing of carbon nanotubes: are they asbestos-like? Fullerene Sci Technol 9: 251-254, 1997.
15. Junqueira LC, Bignolas G, and Brentani RR. Picrosirius staining plus polarization microscopy, a specific method for collagen detection in tissue sections. Histochem J 11: 447-455, 1979.
16. Lam CW, James JT, McCluskey R, and Hunter RL. Pulmonary toxicity of carbon nanotubes in mice 7 and 90 days after intratracheal instillation. Toxicol Sci 77: 126-134, 2004.
17. Maynard AD, Baron PA, Foley M, Shvedova AA, Kisin ER, and Castranova V. Exposure to carbon nanotube material: aerosol release during the handling of unrefined single walled carbon nanotube material. J Toxicol Environ Health 67: 87-107, 2004.
18. NIOSH. Pocket Guide to Chemical Hazards-Index of chemical names. Cincinnati, OH: NIOSH, 2004 (NIOSH publication no. 97-140).
19. Oberdorster G, Sharp Z, Atudorei V, Elder A, Gelein R, Lunts A, Kreyling W, and Cox C. Extrapulmonary translocation of ultrafine carbon particles following whole-body inhalation exposure of rats. J Toxicol Environ Health A 65: 1531-1543, 2002.
20. Piguet PF, Collart MA, Grau GE, Sappino AP, and Vassalli P. Requirement of tumour necrosis factor for development of silica-induced pulmonary fibrosis. Nature 344: 245-247, 1990.
21. Rao GV, Tinkle S, Weissman DN, Antonini JM, Kashon ML, Salmen R, Battelli LA, Willard PA, Hoover MD, and Hubbs AF. Efficacy of a technique for exposing the mouse lung to particles aspirated from the pharynx. J Toxicol Environ Health 66: 1441-1452, 2003.
22. Roco MC. Science and technology integration for increased human potential and societal outcomes. Ann NY Acad Sci 1013: 1-16, 2004.
23. Royal Society and Royal Academy of Engineering. Nanoscience and Nanotechnologies. London: Royal Society and Royal Academy of Engineering, 2004 (http://www.nanotec.org.uk/finalReport.htm).
24. Scott CD, Povitsky A, Dateo C, Gokcen T, Willis PA, and Smalley RE. Iron catalyst chemistry in modeling a high-pressure carbon monoxide nanotube reactor. J Nanosci Nanotechnol 3: 63-73, 2003.
25. Shvedova AA, Kisin ER, Murray AR, Schwegler-Berry D, Gandelsman VZ, Baron P, Maynard A, Gunther MR, and Castranova V. Exposure of human bronchial epithelial cells to carbon nanotubes causes oxidative stress and cytotoxicity. In: Proc Soc Free Rad Research Meeting, European Section, June 26-29, 2003. Ioannina, Greece: 2004, p. 91-103.
26. Stone KC, Mercer RR, Freeman BA, Chang LY, and Crapo JD. Distribution of lung cell numbers and volumes between alveolar and nonalveolar tissue. Am Rev Respir Dis 146: 454-456, 1992.
27. Tao F, Gonzalez-Flecha B, and Kobzik L. Reactive oxygen species in pulmonary inflammation by ambient particulates. Free Radic Biol Med 35: 327-340, 2003.
28. Underwood EE. Quantitative Stereology. Reading, MA: Addison-Wesley, 1970.
29. Warheit DB, Laurence BR, Reed KL, Roach DH, Reynolds GA, and Webb TR. Comparative pulmonary toxicity assessment of single-wall carbon nanotubes in rats. Toxicol Sci 77: 117-125, 2004.