Instillation versus inhalation of multiwalled carbon nanotubes: Exposure-related health effects, clearance, and the role of particle characteristics

ACS Nano

Volumn 8, Issue 9, 2014, Pages 8911-8931

  Silva, Rona M ^a   Doudrick, Kyle ^b   Franzi, Lisa M ^c   Teesy, Christel ^a   Anderson, Donald S ^a   Wu, Zheqiong ^d   Mitra, Somenath ^d   Vu, Vincent ^a   Dutrow, Gavin ^a   Evans, James E ^a,e   Westerhoff, Paul ^b   Van Winkle, Laura S ^a   Raabe, Otto G ^a   Pinkerton, Kent E ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b AZ 85281   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d NEW JERSEY INSTITUTE OF TECHNOLOGY   (United States)

^e PACIFIC NORTHWEST NATIONAL LABORATORY   (United States)

Author keywords

engineered nanomaterial; inflammation; inhalation exposure; multiwalled carbon nanotube (MWCNT); pulmonary toxicity

Indexed keywords

BIOLOGICAL ORGANS; CARBON; HISTOLOGY; MACROPHAGES; PATHOLOGY; SUSPENSIONS (FLUIDS); THERMOANALYSIS; TISSUE; TOXICITY; YARN;

BRONCHOALVEOLAR LAVAGE FLUID; INFLAMMATION; INHALATION EXPOSURE; INTRATRACHEAL INSTILLATION; MULTIWALLED CARBON NANOTUBE (MWCNTS); NANOMATERIAL; PHYSICOCHEMICAL CHARACTERISTICS; PULMONARY TOXICITY;

MULTIWALLED CARBON NANOTUBES (MWCN);

CARBON NANOTUBE; CARBOXYLIC ACID; WATER;

ANIMAL; BRONCHOALVEOLAR LAVAGE FLUID; CELL DIFFERENTIATION; CHEMISTRY; CYTOLOGY; DOSE RESPONSE; DRUG EFFECTS; DRUG INSTILLATION; HEALTH; INHALATIONAL DRUG ADMINISTRATION; MACROPHAGE; MALE; NEUTROPHIL; PHYSICAL CHEMISTRY; RAT; SPRAGUE DAWLEY RAT; TOXICITY TESTING;

ADMINISTRATION, INHALATION; ANIMALS; BRONCHOALVEOLAR LAVAGE FLUID; CARBOXYLIC ACIDS; CELL DIFFERENTIATION; DOSE-RESPONSE RELATIONSHIP, DRUG; HEALTH; INSTILLATION, DRUG; MACROPHAGES; MALE; NANOTUBES, CARBON; NEUTROPHILS; PHYSICOCHEMICAL PROCESSES; RATS; RATS, SPRAGUE-DAWLEY; TOXICITY TESTS; WATER;

EID: 84924478809     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/nn503887r     Document Type: Article

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