Equivalent titanium dioxide nanoparticle deposition by intratracheal instillation and whole body inhalation: The effect of dose rate on acute respiratory tract inflammation

Particle and Fibre Toxicology

Volumn 11, Issue 1, 2014, Pages

  Baisch, Brittany L ^a   Corson, Nancy M ^a   Wade Mercer, Pamela ^a   Gelein, Robert ^a   Kennell, Andrea J ^a   Oberdörster, Günter ^a   Elder, Alison ^a  

^a UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

Author keywords

Acute inflammation; Bronchoalveolar lavage; Dose rate; Intratracheal instillation; Nanoparticle; Respiratory toxicology; Titanium dioxide; Whole body inhalation

Indexed keywords

HEME OXYGENASE 1; MACROPHAGE INFLAMMATORY PROTEIN 2; MONOCYTE CHEMOTACTIC PROTEIN 1; NANOPARTICLE; TITANIUM DIOXIDE NANOPARTICLE; UNCLASSIFIED DRUG;

ACUTE DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL COMPARTMENTALIZATION; CELL VIABILITY; CONTROLLED STUDY; HYDRODYNAMICS; INFLAMMATORY CELL; LONG TERM EXPOSURE; LUNG BURDEN; LUNG LAVAGE; LUNG PARENCHYMA; MALE; MEDIATOR RELEASE; NEUTROPHIL; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; RAT; RESPIRATORY TRACT INFLAMMATION;

RATTUS; RODENTIA;

ADMINISTRATION, INHALATION; ANIMALS; BODY BURDEN; BRONCHOALVEOLAR LAVAGE FLUID; INFLAMMATION; INHALATION EXPOSURE; INTUBATION, INTRATRACHEAL; LUNG; MALE; NANOPARTICLES; NEUTROPHIL INFILTRATION; OXIDATIVE STRESS; PARTICLE SIZE; PNEUMONIA; RATS; RATS, INBRED F344; RESPIRATORY TRACT DISEASES; RISK ASSESSMENT; SOLUBILITY; THERAPEUTIC IRRIGATION; TITANIUM;

EID: 84892747331     PISSN: None     EISSN: 17438977     Source Type: Journal    
DOI: 10.1186/1743-8977-11-5     Document Type: Article

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