-
1
-
-
84923357083
-
Homeostasis, inflammation, and disease susceptibility
-
Kotas ME, Medzhitov R. Homeostasis, inflammation, and disease susceptibility. Cell 2015; 160: 816-827.
-
(2015)
Cell
, vol.160
, pp. 816-827
-
-
Kotas, M.E.1
Medzhitov, R.2
-
2
-
-
77950343791
-
Pattern recognition receptors and inflammation
-
Takeuchi O, Akira S. Pattern recognition receptors and inflammation. Cell 2010; 140: 805-820.
-
(2010)
Cell
, vol.140
, pp. 805-820
-
-
Takeuchi, O.1
Akira, S.2
-
3
-
-
84928568835
-
IL-6 as a keystone cytokine in health and disease
-
Hunter CA, Jones SA. IL-6 as a keystone cytokine in health and disease. Nat Immunol 2015; 16: 448-457.
-
(2015)
Nat Immunol
, vol.16
, pp. 448-457
-
-
Hunter, C.A.1
Jones, S.A.2
-
4
-
-
84937779845
-
Guarding the frontiers: The biology of type III interferons
-
Wack A, Terczyńska-Dyla E, Hartmann R. Guarding the frontiers: the biology of type III interferons. Nat Immunol 2015; 16: 802-809.
-
(2015)
Nat Immunol
, vol.16
, pp. 802-809
-
-
Wack, A.1
Terczyńska-Dyla, E.2
Hartmann, R.3
-
5
-
-
84925441813
-
Control of adaptive immunity by the innate immune system
-
Iwasaki A, Medzhitov R. Control of adaptive immunity by the innate immune system. Nat Immunol 2015; 16: 343-353.
-
(2015)
Nat Immunol
, vol.16
, pp. 343-353
-
-
Iwasaki, A.1
Medzhitov, R.2
-
6
-
-
79956300649
-
Toll-like receptors and their crosstalk with other innate receptors in infection and immunity
-
Kawai T, Akira S. Toll-like receptors and their crosstalk with other innate receptors in infection and immunity. Immunity 2011; 34: 637-650.
-
(2011)
Immunity
, vol.34
, pp. 637-650
-
-
Kawai, T.1
Akira, S.2
-
7
-
-
84928888455
-
Contribution of Toll-like receptors to the control of hepatitis B virus infection by initiating antiviral innate responses and promoting specific adaptive immune responses
-
Ma Z, Zhang E, Yang D, Lu M. Contribution of Toll-like receptors to the control of hepatitis B virus infection by initiating antiviral innate responses and promoting specific adaptive immune responses. Cell Mol Immunol 2015; 12: 273-282.
-
(2015)
Cell Mol Immunol
, vol.12
, pp. 273-282
-
-
Ma, Z.1
Zhang, E.2
Yang, D.3
Lu, M.4
-
8
-
-
84906858463
-
TLR2 and TLR4 signaling pathways are required for recombinant Brucella abortus BCSP31-induced cytokine production, functional upregulation of mouse macrophages, and the Th1 immune response in vivo and in vitro
-
Li JY, Liu Y, Gao XX, Gao X, Cai H. TLR2 and TLR4 signaling pathways are required for recombinant Brucella abortus BCSP31-induced cytokine production, functional upregulation of mouse macrophages, and the Th1 immune response in vivo and in vitro. Cell Mol Immunol 2014; 11: 477-494.
-
(2014)
Cell Mol Immunol
, vol.11
, pp. 477-494
-
-
Li, J.Y.1
Liu, Y.2
Gao, X.X.3
Gao, X.4
Cai, H.5
-
9
-
-
84944897402
-
Kinases Mst1 and Mst2 positively regulate phagocytic induction of reactive oxygen species and bactericidal activity
-
Geng J, Sun X, Wang P, Zhang S, Wang X, Wu H et al. Kinases Mst1 and Mst2 positively regulate phagocytic induction of reactive oxygen species and bactericidal activity. Nat Immunol 2015; 16: 1142-1152.
-
(2015)
Nat Immunol
, vol.16
, pp. 1142-1152
-
-
Geng, J.1
Sun, X.2
Wang, P.3
Zhang, S.4
Wang, X.5
Wu, H.6
-
10
-
-
84944895593
-
De-Mst-ifying microbicidal killing
-
Stuart LM, Lacy-Hulbert A. De-Mst-ifying microbicidal killing. Nat Immunol 2015; 16: 1107-1118.
-
(2015)
Nat Immunol
, vol.16
, pp. 1107-1118
-
-
Stuart, L.M.1
Lacy-Hulbert, A.2
-
11
-
-
33750984771
-
RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates
-
Pichlmair A, Schulz O, Tan CP, Näslund TI, Liljeström P, Weber F et al. RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates. Science 2006; 314: 997-1001.
-
(2006)
Science
, vol.314
, pp. 997-1001
-
-
Pichlmair, A.1
Schulz, O.2
Tan, C.P.3
Näslund, T.I.4
Liljeström, P.5
Weber, F.6
-
12
-
-
33646342149
-
Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses
-
Kato H, Takeuchi O, Sato S, Yoneyama M, Yamamoto M, Matsui K et al. Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses. Nature 2006; 441: 101-105.
-
(2006)
Nature
, vol.441
, pp. 101-105
-
-
Kato, H.1
Takeuchi, O.2
Sato, S.3
Yoneyama, M.4
Yamamoto, M.5
Matsui, K.6
-
13
-
-
84873724533
-
Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA
-
Wu J, Sun L, Chen X, Du F, Shi H, Chen C et al. Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA. Science 2013; 339: 826-830.
-
(2013)
Science
, vol.339
, pp. 826-830
-
-
Wu, J.1
Sun, L.2
Chen, X.3
Du, F.4
Shi, H.5
Chen, C.6
-
14
-
-
84873711885
-
Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type i interferon pathway
-
Sun L, Wu J, Du F, Chen X, Chen ZJ. Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway. Science 2013; 339: 786-791.
-
(2013)
Science
, vol.339
, pp. 786-791
-
-
Sun, L.1
Wu, J.2
Du, F.3
Chen, X.4
Chen, Z.J.5
-
15
-
-
84937897202
-
Molecular basis for the specific recognition of the metazoan cyclic GMP-AMP by the innate immune adaptor protein STING
-
Shi H, Wu J, Chen ZJ, Chen C. Molecular basis for the specific recognition of the metazoan cyclic GMP-AMP by the innate immune adaptor protein STING. Proc Natl Acad Sci USA 2015; 112: 8947-8952.
-
(2015)
Proc Natl Acad Sci USA
, vol.112
, pp. 8947-8952
-
-
Shi, H.1
Wu, J.2
Chen, Z.J.3
Chen, C.4
-
16
-
-
63649133278
-
AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC
-
Hornung V, Ablasser A, Charrel-Dennis M, Bauernfeind F, Horvath G, Caffrey DR et al. AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC. Nature 2009; 458: 514-518.
-
(2009)
Nature
, vol.458
, pp. 514-518
-
-
Hornung, V.1
Ablasser, A.2
Charrel-Dennis, M.3
Bauernfeind, F.4
Horvath, G.5
Caffrey, D.R.6
-
17
-
-
60749136484
-
An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome
-
Bürckstümmer T, Baumann C, Blüml S, Dixit E, Dürnberger G, Jahn H et al. An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome. Nat Immunol 2009; 10: 266-272.
-
(2009)
Nat Immunol
, vol.10
, pp. 266-272
-
-
Bürckstümmer, T.1
Baumann, C.2
Blüml, S.3
Dixit, E.4
Dürnberger, G.5
Jahn, H.6
-
18
-
-
80052969639
-
The helicase DDX41 senses intracellular DNA mediated by the adaptor STING in dendritic cells
-
Zhang Z, Yuan B, Bao M, Lu N, Kim T, Liu YJ. The helicase DDX41 senses intracellular DNA mediated by the adaptor STING in dendritic cells. Nat Immunol 2011; 12: 959-965.
-
(2011)
Nat Immunol
, vol.12
, pp. 959-965
-
-
Zhang, Z.1
Yuan, B.2
Bao, M.3
Lu, N.4
Kim, T.5
Liu, Y.J.6
-
19
-
-
84869403247
-
The helicase DDX41 recognizes the bacterial secondary messengers cyclic di-GMP and cyclic di-AMP to activate a type i interferon immune response
-
Parvatiyar K, Zhang Z, Teles RM, Ouyang S, Jiang Y, Iyer SS et al. The helicase DDX41 recognizes the bacterial secondary messengers cyclic di-GMP and cyclic di-AMP to activate a type I interferon immune response. Nat Immunol 2012; 13: 1155-1161.
-
(2012)
Nat Immunol
, vol.13
, pp. 1155-1161
-
-
Parvatiyar, K.1
Zhang, Z.2
Teles, R.M.3
Ouyang, S.4
Jiang, Y.5
Iyer, S.S.6
-
20
-
-
84901038448
-
Rad50-CARD9 interactions link cytosolic DNA sensing to IL-1β production
-
Roth S, Rottach A, Lotz-Havla AS, Laux V, Muschaweckh A, Gersting SW et al. Rad50-CARD9 interactions link cytosolic DNA sensing to IL-1β production. Nat Immunol 2014; 15: 538-545.
-
(2014)
Nat Immunol
, vol.15
, pp. 538-545
-
-
Roth, S.1
Rottach, A.2
Lotz-Havla, A.S.3
Laux, V.4
Muschaweckh, A.5
Gersting, S.W.6
-
21
-
-
84901013889
-
Rad50 and CARD9, missing links in cytosolic DNA-stimulated inflammation
-
Bowie AG. Rad50 and CARD9, missing links in cytosolic DNA-stimulated inflammation. Nat Immunol 2014; 15: 534-536.
-
(2014)
Nat Immunol
, vol.15
, pp. 534-536
-
-
Bowie, A.G.1
-
22
-
-
77952566304
-
The cytosolic nucleic acid sensor LRRFIP1 mediates the production of type i interferon via a beta-catenin-dependent pathway
-
Yang P, An H, Liu X, Wen M, Zheng Y, Rui Y et al. The cytosolic nucleic acid sensor LRRFIP1 mediates the production of type I interferon via a beta-catenin-dependent pathway. Nat Immunol 2010; 11: 487-494.
-
(2010)
Nat Immunol
, vol.11
, pp. 487-494
-
-
Yang, P.1
An, H.2
Liu, X.3
Wen, M.4
Zheng, Y.5
Rui, Y.6
-
23
-
-
34547143110
-
DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response
-
Takaoka A, Wang Z, Choi MK, Yanai H, Negishi H, Ban T et al. DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response. Nature 2007; 448: 501-505.
-
(2007)
Nature
, vol.448
, pp. 501-505
-
-
Takaoka, A.1
Wang, Z.2
Choi, M.K.3
Yanai, H.4
Negishi, H.5
Ban, T.6
-
24
-
-
79959377900
-
IFIT1 is an antiviral protein that recognizes 5'-triphosphate RNA
-
Pichlmair A, Lassnig C, Eberle CA, Górna MW, Baumann CL, Burkard TR et al. IFIT1 is an antiviral protein that recognizes 5'-triphosphate RNA. Nat Immunol 2011; 12: 624-630.
-
(2011)
Nat Immunol
, vol.12
, pp. 624-630
-
-
Pichlmair, A.1
Lassnig, C.2
Eberle, C.A.3
Górna, M.W.4
Baumann, C.L.5
Burkard, T.R.6
-
25
-
-
84941954118
-
Sequence-specific activation of the DNA sensor cGAS by Y-form DNA structures as found in primary HIV-1 cDNA
-
Herzner AM, Hagmann CA, Goldeck M, Wolter S, Kübler K, Wittmann S et al. Sequence-specific activation of the DNA sensor cGAS by Y-form DNA structures as found in primary HIV-1 cDNA. Nat Immunol 2015; 16: 1025-1033.
-
(2015)
Nat Immunol
, vol.16
, pp. 1025-1033
-
-
Herzner, A.M.1
Hagmann, C.A.2
Goldeck, M.3
Wolter, S.4
Kübler, K.5
Wittmann, S.6
-
26
-
-
84941946959
-
Reading the fine print: Sequence-specific activation of cGAS
-
Chiang JJ, Gack MU. Reading the fine print: sequence-specific activation of cGAS. Nat Immunol 2015; 16: 1009-1010.
-
(2015)
Nat Immunol
, vol.16
, pp. 1009-1010
-
-
Chiang, J.J.1
Gack, M.U.2
-
27
-
-
84925412026
-
Sox2 functions as a sequence-specific DNA sensor in neutrophils to initiate innate immunity against microbial infection
-
Xia P, Wang S, Ye B, Du Y, Huang G, Zhu P et al. Sox2 functions as a sequence-specific DNA sensor in neutrophils to initiate innate immunity against microbial infection. Nat Immunol 2015; 16: 366-375.
-
(2015)
Nat Immunol
, vol.16
, pp. 366-375
-
-
Xia, P.1
Wang, S.2
Ye, B.3
Du, Y.4
Huang, G.5
Zhu, P.6
-
28
-
-
84925459815
-
Hornung V1. Sox2 as a servant of two masters
-
Mankan AK1. Hornung V1. Sox2 as a servant of two masters. Nat Immunol 2015; 16: 335-336.
-
(2015)
Nat Immunol
, vol.16
, pp. 335-336
-
-
Mankan, A.K.1
-
29
-
-
84977580362
-
Neutrophil sensing of cytoplasmic, pathogenic DNA in a cGAS-STING-independent manner
-
Yu Z, Chen T, Cao X. Neutrophil sensing of cytoplasmic, pathogenic DNA in a cGAS-STING-independent manner. Cell Mol Immunol 2016; 13: 411-414.
-
(2016)
Cell Mol Immunol
, vol.13
, pp. 411-414
-
-
Yu, Z.1
Chen, T.2
Cao, X.3
-
30
-
-
0038824980
-
An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acid
-
Chamaillard M, Hashimoto M, Horie Y, Masumoto J, Qiu S, Saab L et al. An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acid. Nat Immunol 2003; 4: 702-707.
-
(2003)
Nat Immunol
, vol.4
, pp. 702-707
-
-
Chamaillard, M.1
Hashimoto, M.2
Horie, Y.3
Masumoto, J.4
Qiu, S.5
Saab, L.6
-
31
-
-
84969257253
-
NAIP proteins are required for cytosolic detection of specific bacterial ligands in vivo
-
Rauch I, Tenthorey JL, Nichols RD, Al Moussawi K, Kang JJ, Kang C et al. NAIP proteins are required for cytosolic detection of specific bacterial ligands in vivo. J Exp Med 2016; 213: 657-665.
-
(2016)
J Exp Med
, vol.213
, pp. 657-665
-
-
Rauch, I.1
Tenthorey, J.L.2
Nichols, R.D.3
Al Moussawi, K.4
Kang, J.J.5
Kang, C.6
-
32
-
-
73849121209
-
Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry
-
Travassos LH, Carneiro LA, Ramjeet M, Hussey S, Kim YG, Magalhães JG et al. Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry. Nat Immunol 2010; 11: 55-62.
-
(2010)
Nat Immunol
, vol.11
, pp. 55-62
-
-
Travassos, L.H.1
Carneiro, L.A.2
Ramjeet, M.3
Hussey, S.4
Kim, Y.G.5
Magalhães, J.G.6
-
33
-
-
84941953933
-
Autophagy and autophagy-related proteins in the immune system
-
Shibutani ST, Saitoh T, Nowag H, Münz C, Yoshimori T. Autophagy and autophagy-related proteins in the immune system. Nat Immunol 2015; 16: 1014-1024.
-
(2015)
Nat Immunol
, vol.16
, pp. 1014-1024
-
-
Shibutani, S.T.1
Saitoh, T.2
Nowag, H.3
Münz, C.4
Yoshimori, T.5
-
36
-
-
84904692363
-
The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation
-
Franklin BS, Bossaller L, De Nardo D, Ratter JM, Stutz A, Engels G et al. The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation. Nat Immunol 2014; 15: 727-737.
-
(2014)
Nat Immunol
, vol.15
, pp. 727-737
-
-
Franklin, B.S.1
Bossaller, L.2
De Nardo, D.3
Ratter, J.M.4
Stutz, A.5
Engels, G.6
-
37
-
-
84904646033
-
The NLRP3 inflammasome is released as a particulate danger signal that amplifies the inflammatory response
-
Baroja-Mazo A, Martín-Sánchez F, Gomez AI, Martínez CM, Amores-Iniesta J, Compan V et al. The NLRP3 inflammasome is released as a particulate danger signal that amplifies the inflammatory response. Nat Immunol 2014; 15: 738-748.
-
(2014)
Nat Immunol
, vol.15
, pp. 738-748
-
-
Baroja-Mazo, A.1
Martín-Sánchez, F.2
Gomez, A.I.3
Martínez, C.M.4
Amores-Iniesta, J.5
Compan, V.6
-
38
-
-
84928545520
-
The transcription factor IRF1 and guanylate-binding proteins target activation of the AIM2 inflammasome by Francisella infection
-
Man SM, Karki R, Malireddi RK, Neale G, Vogel P, Yamamoto M et al. The transcription factor IRF1 and guanylate-binding proteins target activation of the AIM2 inflammasome by Francisella infection. Nat Immunol 2015; 16: 467-475.
-
(2015)
Nat Immunol
, vol.16
, pp. 467-475
-
-
Man, S.M.1
Karki, R.2
Malireddi, R.K.3
Neale, G.4
Vogel, P.5
Yamamoto, M.6
-
39
-
-
84928538482
-
Guanylate-binding proteins promote activation of the AIM2 inflam-masome during infection with Francisella novicida
-
Meunier E, Wallet P, Dreier RF, Costanzo S, Anton L, Rühl S et al. Guanylate-binding proteins promote activation of the AIM2 inflam-masome during infection with Francisella novicida. Nat Immunol 2015; 16: 476-484.
-
(2015)
Nat Immunol
, vol.16
, pp. 476-484
-
-
Meunier, E.1
Wallet, P.2
Dreier, R.F.3
Costanzo, S.4
Anton, L.5
Rühl, S.6
-
40
-
-
74049126045
-
Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for in terleukin 1 beta production
-
Poeck H, Bscheider M, Gross O, Finger K, Roth S, Rebsamen M et al. Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for in terleukin 1 beta production. Nat Immunol 2010; 11: 63-69.
-
(2010)
Nat Immunol
, vol.11
, pp. 63-69
-
-
Poeck, H.1
Bscheider, M.2
Gross, O.3
Finger, K.4
Roth, S.5
Rebsamen, M.6
-
41
-
-
84911192502
-
RNA viruses promote activation of the NLRP3 inflammasome through a RIP1-RIP3-DRP1 signaling pathway
-
Wang X, Jiang W, Yan Y, Gong T, Han J, Tian Z et al. RNA viruses promote activation of the NLRP3 inflammasome through a RIP1-RIP3-DRP1 signaling pathway. Nat Immunol 2014; 15: 1126-1133.
-
(2014)
Nat Immunol
, vol.15
, pp. 1126-1133
-
-
Wang, X.1
Jiang, W.2
Yan, Y.3
Gong, T.4
Han, J.5
Tian, Z.6
-
42
-
-
84901057834
-
Translational control of immune responses: From transcripts to translatomes
-
Piccirillo CA, Bjur E, Topisirovic I, Sonenberg N, Larsson O. Translational control of immune responses: from transcripts to translatomes. Nat Immunol 2014; 15: 503-511.
-
(2014)
Nat Immunol
, vol.15
, pp. 503-511
-
-
Piccirillo, C.A.1
Bjur, E.2
Topisirovic, I.3
Sonenberg, N.4
Larsson, O.5
-
43
-
-
84901032555
-
Post-transcriptional coordination of immunological responses by RNA-binding proteins
-
Kafasla P, Skliris A, Kontoyiannis DL. Post-transcriptional coordination of immunological responses by RNA-binding proteins. Nat Immunol 2014; 15: 492-502.
-
(2014)
Nat Immunol
, vol.15
, pp. 492-502
-
-
Kafasla, P.1
Skliris, A.2
Kontoyiannis, D.L.3
-
44
-
-
33645809747
-
Coordinated binding of NF-κB family members in the response of human cells to lipopolysaccharide
-
Schreiber J, Jenner RG, Murray HL, Gerber GK, Gifford DK, Young RA. Coordinated binding of NF-κB family members in the response of human cells to lipopolysaccharide. Proc Natl Acad Sci USA 2006; 103: 5899-5904.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 5899-5904
-
-
Schreiber, J.1
Jenner, R.G.2
Murray, H.L.3
Gerber, G.K.4
Gifford, D.K.5
Young, R.A.6
-
45
-
-
84959894007
-
Long noncoding RNAs in innate immunity
-
Zhang Y, Cao X. Long noncoding RNAs in innate immunity. Cell Mol Immunol 2016; 13: 138-147.
-
(2016)
Cell Mol Immunol
, vol.13
, pp. 138-147
-
-
Zhang, Y.1
Cao, X.2
-
46
-
-
84901049034
-
Noncoding RNA and its associated proteins as regulatory elements of the immune system
-
Turner M, Galloway A, Vigorito E. Noncoding RNA and its associated proteins as regulatory elements of the immune system. Nat Immunol 2014; 15: 484-491.
-
(2014)
Nat Immunol
, vol.15
, pp. 484-491
-
-
Turner, M.1
Galloway, A.2
Vigorito, E.3
-
47
-
-
84987617604
-
Long noncoding RNA #32 contributes to antiviral responses by controlling interferon-stimulated gene expression
-
Nishitsuji H, Ujino S, Yoshio S, Sugiyama M, Mizokami M, Kanto T et al. Long noncoding RNA #32 contributes to antiviral responses by controlling interferon-stimulated gene expression. Proc Natl Acad Sci USA 2016; 113: 10388-10393.
-
(2016)
Proc Natl Acad Sci USA
, vol.113
, pp. 10388-10393
-
-
Nishitsuji, H.1
Ujino, S.2
Yoshio, S.3
Sugiyama, M.4
Mizokami, M.5
Kanto, T.6
-
48
-
-
77952567987
-
Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities
-
Heinz S, Benner C, Spann N, Bertolino E, Lin YC, Laslo P et al. Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities. Mol Cell 2010; 38: 576-589.
-
(2010)
Mol Cell
, vol.38
, pp. 576-589
-
-
Heinz, S.1
Benner, C.2
Spann, N.3
Bertolino, E.4
Lin, Y.C.5
Laslo, P.6
-
49
-
-
77949977555
-
Identification and characterization of enhancers controlling the inflammatory gene expression program in macrophages
-
Ghisletti S, Barozzi I, Mietton F, Polletti S, De Santa F, Venturini E et al. Identification and characterization of enhancers controlling the inflammatory gene expression program in macrophages. Immunity 2010; 32: 317-328.
-
(2010)
Immunity
, vol.32
, pp. 317-328
-
-
Ghisletti, S.1
Barozzi, I.2
Mietton, F.3
Polletti, S.4
De Santa, F.5
Venturini, E.6
-
50
-
-
84973100782
-
Methyltransferase Dnmt3a upregulates HDAC9 to deacetylate the kinase TBK1 for activation of antiviral innate immunity
-
Li X, Zhang Q, Ding Y, Liu Y, Zhao D, Zhao K et al. Methyltransferase Dnmt3a upregulates HDAC9 to deacetylate the kinase TBK1 for activation of antiviral innate immunity. Nat Immunol 2016; 17: 806-815.
-
(2016)
Nat Immunol
, vol.17
, pp. 806-815
-
-
Li, X.1
Zhang, Q.2
Ding, Y.3
Liu, Y.4
Zhao, D.5
Zhao, K.6
-
51
-
-
84923304136
-
The methyltransferase Setdb2 mediates virus-induced susceptibility to bacterial superinfection
-
Schliehe C, Flynn EK, Vilagos B, Richson U, Swaminathan S, Bosnjak B et al. The methyltransferase Setdb2 mediates virus-induced susceptibility to bacterial superinfection. Nat Immunol 2015; 16: 67-74.
-
(2015)
Nat Immunol
, vol.16
, pp. 67-74
-
-
Schliehe, C.1
Flynn, E.K.2
Vilagos, B.3
Richson, U.4
Swaminathan, S.5
Bosnjak, B.6
-
52
-
-
84942050633
-
Tet2 is required to resolve inflammation by recruiting Hdac2 to specifically repress IL-6
-
Zhang Q, Zhao K, Shen Q, Han Y, Gu Y, Li X et al. Tet2 is required to resolve inflammation by recruiting Hdac2 to specifically repress IL-6. Nature 2015; 525: 389-393.
-
(2015)
Nature
, vol.525
, pp. 389-393
-
-
Zhang, Q.1
Zhao, K.2
Shen, Q.3
Han, Y.4
Gu, Y.5
Li, X.6
-
53
-
-
0037438590
-
Synthesis of glucocorticoid-induced leucine zipper (GILZ) by macrophages: An anti-inflammatory and immunosuppres-sive mechanism shared by glucocorticoids and IL-10
-
Berrebi D, Bruscoli S, Cohen N, Foussat A, Migliorati G, Bouchet-Delbos L et al. Synthesis of glucocorticoid-induced leucine zipper (GILZ) by macrophages: an anti-inflammatory and immunosuppres-sive mechanism shared by glucocorticoids and IL-10. Blood 2003; 101: 729-738.
-
(2003)
Blood
, vol.101
, pp. 729-738
-
-
Berrebi, D.1
Bruscoli, S.2
Cohen, N.3
Foussat, A.4
Migliorati, G.5
Bouchet-Delbos, L.6
-
54
-
-
24144465889
-
Molecular determinants of crosstalk between nuclear receptors and toll-like receptors
-
Ogawa S, Lozach J, Benner C, Pascual G, Tangirala RK, Westin S et al. Molecular determinants of crosstalk between nuclear receptors and toll-like receptors. Cell 2005; 122: 707-721.
-
(2005)
Cell
, vol.122
, pp. 707-721
-
-
Ogawa, S.1
Lozach, J.2
Benner, C.3
Pascual, G.4
Tangirala, R.K.5
Westin, S.6
-
55
-
-
63049122784
-
Cooperative NCoR/SMRT interactions establish a corepressor-based strategy for integration of inflammatory and anti-inflammatory signaling pathways
-
Ghisletti S, Huang W, Jepsen K, Benner C, Hardiman G, Rosenfeld MG et al. Cooperative NCoR/SMRT interactions establish a corepressor-based strategy for integration of inflammatory and anti-inflammatory signaling pathways. Genes Dev 2009; 23: 681-693.
-
(2009)
Genes Dev
, vol.23
, pp. 681-693
-
-
Ghisletti, S.1
Huang, W.2
Jepsen, K.3
Benner, C.4
Hardiman, G.5
Rosenfeld, M.G.6
-
56
-
-
80052020185
-
The orphan nuclear receptor SHP acts as a negative regulator in inflammatory signaling triggered by Toll-like receptors
-
Yuk JM, Shin DM, Lee HM, Kim JJ, Kim SW, Jin HS et al. The orphan nuclear receptor SHP acts as a negative regulator in inflammatory signaling triggered by Toll-like receptors. Nat Immunol 2011; 12: 742-751.
-
(2011)
Nat Immunol
, vol.12
, pp. 742-751
-
-
Yuk, J.M.1
Shin, D.M.2
Lee, H.M.3
Kim, J.J.4
Kim, S.W.5
Jin, H.S.6
-
57
-
-
84932186336
-
Impeding the interaction between Nur77 and p38 reduces LPS-induced inflammation
-
Li L, Liu Y, Chen HZ, Li FW, Wu JF, Zhang HK et al. Impeding the interaction between Nur77 and p38 reduces LPS-induced inflammation. Nat Chem Biol 2015; 11: 339-346.
-
(2015)
Nat Chem Biol
, vol.11
, pp. 339-346
-
-
Li, L.1
Liu, Y.2
Chen, H.Z.3
Li, F.W.4
Wu, J.F.5
Zhang, H.K.6
-
58
-
-
63049083734
-
A Nurr1/CoREST pathway in microglia and astrocytes protects dopaminergic neurons from inflammation-induced death
-
Saijo K, Winner B, Carson CT, Collier JG, Boyer L, Rosenfeld MG et al. A Nurr1/CoREST pathway in microglia and astrocytes protects dopaminergic neurons from inflammation-induced death. Cell 2009; 137: 47-59.
-
(2009)
Cell
, vol.137
, pp. 47-59
-
-
Saijo, K.1
Winner, B.2
Carson, C.T.3
Collier, J.G.4
Boyer, L.5
Rosenfeld, M.G.6
-
59
-
-
84947768583
-
Transcription factor Nr4a1 couples sympathetic and inflammatory cues in CNS-recruited macrophages to limit neuroinflammation
-
Shaked I, Hanna RN, Shaked H, Chodaczek G, Nowyhed HN, Tweet G et al. Transcription factor Nr4a1 couples sympathetic and inflammatory cues in CNS-recruited macrophages to limit neuroinflammation. Nat Immunol 2015; 16: 1228-1234.
-
(2015)
Nat Immunol
, vol.16
, pp. 1228-1234
-
-
Shaked, I.1
Hanna, R.N.2
Shaked, H.3
Chodaczek, G.4
Nowyhed, H.N.5
Tweet, G.6
-
60
-
-
84901070124
-
Unconventional post-translational modifications in immunological signaling
-
Mowen KA, David M. Unconventional post-translational modifications in immunological signaling. Nat Immunol 2014; 15: 512-520.
-
(2014)
Nat Immunol
, vol.15
, pp. 512-520
-
-
Mowen, K.A.1
David, M.2
-
61
-
-
84990855979
-
Post-translational modification control of innate immunity
-
Liu J, Qian C, Cao X. Post-translational modification control of innate immunity. Immunity 2016; 45: 15-30.
-
(2016)
Immunity
, vol.45
, pp. 15-30
-
-
Liu, J.1
Qian, C.2
Cao, X.3
-
62
-
-
84894477392
-
K63-linked polyubiquitination of transcription factor IRF1 is essential for IL-1-induced production of chemokines CXCL10 and CCL5
-
Harikumar KB, Yester JW, Surace MJ, Oyeniran C, Price MM, Huang WC et al. K63-linked polyubiquitination of transcription factor IRF1 is essential for IL-1-induced production of chemokines CXCL10 and CCL5. Nat Immunol 2014; 15: 231-238.
-
(2014)
Nat Immunol
, vol.15
, pp. 231-238
-
-
Harikumar, K.B.1
Yester, J.W.2
Surace, M.J.3
Oyeniran, C.4
Price, M.M.5
Huang, W.C.6
-
63
-
-
84906859353
-
K63-linked polyubiquitination of IRF1: An essential step in the IL-1 signaling cascade
-
Wang T, Wang J. K63-linked polyubiquitination of IRF1: an essential step in the IL-1 signaling cascade. Cell Mol Immunol 2014; 11: 407-409.
-
(2014)
Cell Mol Immunol
, vol.11
, pp. 407-409
-
-
Wang, T.1
Wang, J.2
-
64
-
-
84928570108
-
The methyltransferase Ezh2 controls cell adhesion and migration through direct methylation of the extranuclear regulatory protein talin
-
Gunawan M, Venkatesan N, Loh JT, Wong JF, Berger H, Neo WH et al. The methyltransferase Ezh2 controls cell adhesion and migration through direct methylation of the extranuclear regulatory protein talin. Nat Immunol 2015; 16: 505-516.
-
(2015)
Nat Immunol
, vol.16
, pp. 505-516
-
-
Gunawan, M.1
Venkatesan, N.2
Loh, J.T.3
Wong, J.F.4
Berger, H.5
Neo, W.H.6
-
65
-
-
84931432951
-
The deacetylase Sirt1 is an essential regulator of Aire-mediated induction of central immunological tolerance
-
Chuprin A, Avin A, Goldfarb Y, Herzig Y, Levi B, Jacob A et al. The deacetylase Sirt1 is an essential regulator of Aire-mediated induction of central immunological tolerance. Nat Immunol 2015; 16: 737-745.
-
(2015)
Nat Immunol
, vol.16
, pp. 737-745
-
-
Chuprin, A.1
Avin, A.2
Goldfarb, Y.3
Herzig, Y.4
Levi, B.5
Jacob, A.6
-
66
-
-
5444223519
-
The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses
-
Boone DL, Turer EE, Lee EG, Ahmad RC, Wheeler MT, Tsui C et al. The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses. Nat Immunol 2004; 5: 1052-1060.
-
(2004)
Nat Immunol
, vol.5
, pp. 1052-1060
-
-
Boone, D.L.1
Turer, E.E.2
Lee, E.G.3
Ahmad, R.C.4
Wheeler, M.T.5
Tsui, C.6
-
67
-
-
69049086481
-
TANK is a negative regulator of Toll-like receptor signaling and is critical for the prevention of autoimmune nephritis
-
Kawagoe T, Takeuchi O, Takabatake Y, Kato H, Isaka Y, Tsujimura T et al. TANK is a negative regulator of Toll-like receptor signaling and is critical for the prevention of autoimmune nephritis. Nat Immunol 2009; 10: 965-972.
-
(2009)
Nat Immunol
, vol.10
, pp. 965-972
-
-
Kawagoe, T.1
Takeuchi, O.2
Takabatake, Y.3
Kato, H.4
Isaka, Y.5
Tsujimura, T.6
-
68
-
-
84901016154
-
Immune diseases caused by mutations in kinases and components of the ubiquitin system
-
Cohen P. Immune diseases caused by mutations in kinases and components of the ubiquitin system. Nat Immunol 2014; 15: 521-529.
-
(2014)
Nat Immunol
, vol.15
, pp. 521-529
-
-
Cohen, P.1
-
69
-
-
84961115720
-
Ubiquitin in the activation and attenuation of innate antiviral immunity
-
Heaton SM, Borg NA, Dixit VM. Ubiquitin in the activation and attenuation of innate antiviral immunity. J Exp Med 2016; 213: 1-13.
-
(2016)
J Exp Med
, vol.213
, pp. 1-13
-
-
Heaton, S.M.1
Borg, N.A.2
Dixit, V.M.3
-
70
-
-
84946084205
-
Ubiquitin-mediated NFκB degradation pathway
-
Xu H, You M, Shi H, Hou Y. Ubiquitin-mediated NFκB degradation pathway. Cell Mol Immunol 2015; 12: 653-655.
-
(2015)
Cell Mol Immunol
, vol.12
, pp. 653-655
-
-
Xu, H.1
You, M.2
Shi, H.3
Hou, Y.4
-
71
-
-
84923582432
-
The kinase MST4 limits inflammatory responses through direct phosphorylation of the adaptor TRAF6
-
Jiao S, Zhang Z, Li C, Huang M, Shi Z, Wang Y et al. The kinase MST4 limits inflammatory responses through direct phosphorylation of the adaptor TRAF6. Nat Immunol 2015; 16: 246-257.
-
(2015)
Nat Immunol
, vol.16
, pp. 246-257
-
-
Jiao, S.1
Zhang, Z.2
Li, C.3
Huang, M.4
Shi, Z.5
Wang, Y.6
-
72
-
-
84903556575
-
Rhbdd3 controls autoimmunity by suppressing the production of IL-6 by dendritic cells via K27-linked ubiquitination of the regulator NEMO
-
Liu J, Han C, Xie B, Wu Y, Liu S, Chen K et al. Rhbdd3 controls autoimmunity by suppressing the production of IL-6 by dendritic cells via K27-linked ubiquitination of the regulator NEMO. Nat Immunol 2014; 15: 612-622.
-
(2014)
Nat Immunol
, vol.15
, pp. 612-622
-
-
Liu, J.1
Han, C.2
Xie, B.3
Wu, Y.4
Liu, S.5
Chen, K.6
-
73
-
-
84877327205
-
Rhomboid domain-containing protein 3 is a negative regulator of TLR3-triggered natural killer cell activation
-
Liu J, Liu S, Xia M, Xu S, Wang C, Bao Y et al. Rhomboid domain-containing protein 3 is a negative regulator of TLR3-triggered natural killer cell activation. Proc Natl Acad Sci USA 2013; 110: 7814-7819.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 7814-7819
-
-
Liu, J.1
Liu, S.2
Xia, M.3
Xu, S.4
Wang, C.5
Bao, Y.6
-
74
-
-
84855822415
-
Tumor necrosis factor signaling requires iRhom2 to promote trafficking and activation of TACE
-
Adrain C, Zettl M, Christova Y, Taylor N, Freeman M. Tumor necrosis factor signaling requires iRhom2 to promote trafficking and activation of TACE. Science 2012; 335: 225-228.
-
(2012)
Science
, vol.335
, pp. 225-228
-
-
Adrain, C.1
Zettl, M.2
Christova, Y.3
Taylor, N.4
Freeman, M.5
-
75
-
-
84862909285
-
IRhom2 regulation of TACE controls TNF-mediated protection against Listeria and responses to LPS
-
McIlwain DR, Lang PA, Maretzky T, Hamada K, Ohishi K, Maney SK et al. iRhom2 regulation of TACE controls TNF-mediated protection against Listeria and responses to LPS. Science 2012; 335: 229-232.
-
(2012)
Science
, vol.335
, pp. 229-232
-
-
McIlwain, D.R.1
Lang, P.A.2
Maretzky, T.3
Hamada, K.4
Ohishi, K.5
Maney, S.K.6
-
76
-
-
84978699224
-
IRhom2 is essential for innate immunity to DNA viruses by mediating trafficking and stability of the adaptor STING
-
Luo WW, Li S, Li C, Lian H, Yang Q, Zhong B et al. iRhom2 is essential for innate immunity to DNA viruses by mediating trafficking and stability of the adaptor STING. Nat Immunol 2016; 17: 1057-1066.
-
(2016)
Nat Immunol
, vol.17
, pp. 1057-1066
-
-
Luo, W.W.1
Li, S.2
Li, C.3
Lian, H.4
Yang, Q.5
Zhong, B.6
-
77
-
-
84894484608
-
The transcription factor DREAM represses the deubiquitinase A20 and mediates inflammation
-
Tiruppathi C, Soni D, Wang DM, Xue J, Singh V, Thippegowda PB et al. The transcription factor DREAM represses the deubiquitinase A20 and mediates inflammation. Nat Immunol 2014; 15: 239-247.
-
(2014)
Nat Immunol
, vol.15
, pp. 239-247
-
-
Tiruppathi, C.1
Soni, D.2
Wang, D.M.3
Xue, J.4
Singh, V.5
Thippegowda, P.B.6
-
78
-
-
84884355331
-
Histone methyltransfer-ase Ash1l suppresses interleukin-6 production and inflammatory autoimmune diseases by inducing the ubiquitin-editing enzyme A20
-
Xia M, Liu J, Wu X, Liu S, Li G, Han C et al. Histone methyltransfer-ase Ash1l suppresses interleukin-6 production and inflammatory autoimmune diseases by inducing the ubiquitin-editing enzyme A20. Immunity 2013; 39: 470-481.
-
(2013)
Immunity
, vol.39
, pp. 470-481
-
-
Xia, M.1
Liu, J.2
Wu, X.3
Liu, S.4
Li, G.5
Han, C.6
-
79
-
-
84983604685
-
RNF122 suppresses antiviral type i interferon production by targeting RIG-I CARDs to mediate RIG-I degradation
-
Wang W, Jiang M, Liu S, Zhang S, Liu W, Ma Y et al. RNF122 suppresses antiviral type I interferon production by targeting RIG-I CARDs to mediate RIG-I degradation. Proc Natl Acad Sci USA 2016; 113: 9581-9586.
-
(2016)
Proc Natl Acad Sci USA
, vol.113
, pp. 9581-9586
-
-
Wang, W.1
Jiang, M.2
Liu, S.3
Zhang, S.4
Liu, W.5
Ma, Y.6
-
80
-
-
84951310828
-
The tumor suppressor PTEN has a critical role in antiviral innate immunity
-
Li S, Zhu M, Pan R, Fang T, Cao YY, Chen S et al. The tumor suppressor PTEN has a critical role in antiviral innate immunity. Nat Immunol 2016; 17: 241-249.
-
(2016)
Nat Immunol
, vol.17
, pp. 241-249
-
-
Li, S.1
Zhu, M.2
Pan, R.3
Fang, T.4
Cao, Y.Y.5
Chen, S.6
-
81
-
-
84962438844
-
A PTENtial cause for the selectivity of oncolytic viruses?
-
Champion BR, Fisher K, Seymour L. A PTENtial cause for the selectivity of oncolytic viruses? Nat Immunol 2016; 17: 225-226.
-
(2016)
Nat Immunol
, vol.17
, pp. 225-226
-
-
Champion, B.R.1
Fisher, K.2
Seymour, L.3
-
82
-
-
84989851491
-
Identification of a role for TRIM29 in the control of innate immunity in the respiratory tract
-
e-pub ahead of print 3 October
-
Xing J, Weng L, Yuan B, Wang Z, Jia L, Jin R et al. Identification of a role for TRIM29 in the control of innate immunity in the respiratory tract. Nat Immunol; e-pub ahead of print 3 October 2016; doi:10.1038/ni.3580.
-
(2016)
Nat Immunol
-
-
Xing, J.1
Weng, L.2
Yuan, B.3
Wang, Z.4
Jia, L.5
Jin, R.6
-
83
-
-
84955189761
-
Sumoylation coordinates the repression of inflammatory and anti-viral gene-expression programs during innate sensing
-
Decque A, Joffre O, Magalhaes JG, Cossec JC, Blecher-Gonen R, Lapaquette P et al. Sumoylation coordinates the repression of inflammatory and anti-viral gene-expression programs during innate sensing. Nat Immunol 2016; 17: 140-149.
-
(2016)
Nat Immunol
, vol.17
, pp. 140-149
-
-
Decque, A.1
Joffre, O.2
Magalhaes, J.G.3
Cossec, J.C.4
Blecher-Gonen, R.5
Lapaquette, P.6
-
85
-
-
84959917649
-
Molecular mechanisms regulating NLRP3 inflammasome activation
-
Jo EK, Kim JK, Shin DM, Sasakawa C. Molecular mechanisms regulating NLRP3 inflammasome activation. Cell Mol Immunol 2016; 13: 148-159.
-
(2016)
Cell Mol Immunol
, vol.13
, pp. 148-159
-
-
Jo, E.K.1
Kim, J.K.2
Shin, D.M.3
Sasakawa, C.4
-
86
-
-
84896638307
-
The PYRIN domain-only protein POP3 inhibits ALR inflammasomes and regulates responses to infection with DNA viruses
-
Khare S, Ratsimandresy RA, de Almeida L, Cuda CM, Rellick SL, Misharin AV et al. The PYRIN domain-only protein POP3 inhibits ALR inflammasomes and regulates responses to infection with DNA viruses. Nat Immunol 2014; 15: 343-353.
-
(2014)
Nat Immunol
, vol.15
, pp. 343-353
-
-
Khare, S.1
Ratsimandresy, R.A.2
De Almeida, L.3
Cuda, C.M.4
Rellick, S.L.5
Misharin, A.V.6
-
88
-
-
84920990887
-
Dopamine controls systemic inflammation through inhibition of NLRP3 inflam-masome
-
Yan Y, Jiang W, Liu L, Wang X, Ding C, Tian Z et al. Dopamine controls systemic inflammation through inhibition of NLRP3 inflam-masome. Cell 2015; 160: 62-73.
-
(2015)
Cell
, vol.160
, pp. 62-73
-
-
Yan, Y.1
Jiang, W.2
Liu, L.3
Wang, X.4
Ding, C.5
Tian, Z.6
-
89
-
-
84983525884
-
NLRP3 inflamma-some inhibition is disrupted in a group of auto-inflammatory disease CAPS mutations
-
Mortimer L, Moreau F, MacDonald JA, Chadee K. NLRP3 inflamma-some inhibition is disrupted in a group of auto-inflammatory disease CAPS mutations. Nat Immunol 2016; 17: 1176-1186.
-
(2016)
Nat Immunol
, vol.17
, pp. 1176-1186
-
-
Mortimer, L.1
Moreau, F.2
MacDonald, J.A.3
Chadee, K.4
-
90
-
-
84906571225
-
Inflammatory caspases are innate immune receptors for intracellular LPS
-
Shi J, Zhao Y, Wang Y, Gao W, Ding J, Li P et al. Inflammatory caspases are innate immune receptors for intracellular LPS. Nature 2014; 514: 187-192.
-
(2014)
Nature
, vol.514
, pp. 187-192
-
-
Shi, J.1
Zhao, Y.2
Wang, Y.3
Gao, W.4
Ding, J.5
Li, P.6
-
91
-
-
85014723204
-
Responses to LPS boost effector CD8 T-cell accumulation outside of signals 1 and 2
-
e-pub ahead of print 20 July
-
Liu W, Menoret A, Vella AT. Responses to LPS boost effector CD8 T-cell accumulation outside of signals 1 and 2. Cell Mol Immunol; e-pub ahead of print 20 July 2015; doi:10.1038/cmi.2015.69.
-
(2015)
Cell Mol Immunol
-
-
Liu, W.1
Menoret, A.2
Vella, A.T.3
-
92
-
-
84925399854
-
A lectin S-domain receptor kinase mediates lipopolysaccharide sensing in Arabidopsis thaliana
-
Ranf S, Gisch N, Schäffer M, Illig T, Westphal L, Knirel YA et al. A lectin S-domain receptor kinase mediates lipopolysaccharide sensing in Arabidopsis thaliana. Nat Immunol 2015; 16: 426-433.
-
(2015)
Nat Immunol
, vol.16
, pp. 426-433
-
-
Ranf, S.1
Gisch, N.2
Schäffer, M.3
Illig, T.4
Westphal, L.5
Knirel, Y.A.6
-
93
-
-
84925424473
-
A new receptor for LPS
-
Zipfel C. A new receptor for LPS. Nat Immunol 2015; 16: 340-341.
-
(2015)
Nat Immunol
, vol.16
, pp. 340-341
-
-
Zipfel, C.1
-
94
-
-
84862622032
-
Cross-interference of RLR and TLR signaling pathways modulates antibacterial T cell responses
-
Negishi H, Yanai H, Nakajima A, Koshiba R, Atarashi K, Matsuda A et al. Cross-interference of RLR and TLR signaling pathways modulates antibacterial T cell responses. Nat Immunol 2012; 13: 659-666.
-
(2012)
Nat Immunol
, vol.13
, pp. 659-666
-
-
Negishi, H.1
Yanai, H.2
Nakajima, A.3
Koshiba, R.4
Atarashi, K.5
Matsuda, A.6
-
95
-
-
84862159395
-
Negative regulation of the type i interferon signaling pathway by synthetic Toll-like receptor 7 ligands
-
Forsbach A, Müller C, Montino C, Kritzler A, Nguyen T, Weeratna R et al. Negative regulation of the type I interferon signaling pathway by synthetic Toll-like receptor 7 ligands. J Interferon Cytokine Res 2012; 32: 254-268.
-
(2012)
J Interferon Cytokine Res
, vol.32
, pp. 254-268
-
-
Forsbach, A.1
Müller, C.2
Montino, C.3
Kritzler, A.4
Nguyen, T.5
Weeratna, R.6
-
96
-
-
77951902675
-
NLRC5 negatively regulates the NF-kappaB and type i interferon signaling pathways
-
Cui J, Zhu L, Xia X, Wang HY, Legras X, Hong J et al. NLRC5 negatively regulates the NF-kappaB and type I interferon signaling pathways. Cell 2010; 141: 483-496.
-
(2010)
Cell
, vol.141
, pp. 483-496
-
-
Cui, J.1
Zhu, L.2
Xia, X.3
Wang, H.Y.4
Legras, X.5
Hong, J.6
-
97
-
-
38749097018
-
NLRX1 is a regulator of mitochondrial antiviral immunity
-
Moore CB, Bergstralh DT, Duncan JA, Lei Y, Morrison TE, Zimmer-mann AG et al. NLRX1 is a regulator of mitochondrial antiviral immunity. Nature 2008; 451: 573-577.
-
(2008)
Nature
, vol.451
, pp. 573-577
-
-
Moore, C.B.1
Bergstralh, D.T.2
Duncan, J.A.3
Lei, Y.4
Morrison, T.E.5
Zimmer-Mann, A.G.6
-
98
-
-
79959350721
-
NLRX1 protein attenuates inflammatory responses to infection by interfering with the RIG-I-MAVS and TRAF6-NF-κB signaling pathways
-
Allen IC, Moore CB, Schneider M, Lei Y, Davis BK, Scull MA et al. NLRX1 protein attenuates inflammatory responses to infection by interfering with the RIG-I-MAVS and TRAF6-NF-κB signaling pathways. Immunity 2011; 34: 854-865.
-
(2011)
Immunity
, vol.34
, pp. 854-865
-
-
Allen, I.C.1
Moore, C.B.2
Schneider, M.3
Lei, Y.4
Davis, B.K.5
Scull, M.A.6
-
99
-
-
84896344782
-
NLRC3, a member of the NLR family of proteins, is a negative regulator of innate immune signaling induced by the DNA sensor STING
-
Zhang L, Mo J, Swanson KV, Wen H, Petrucelli A, Gregory SM et al. NLRC3, a member of the NLR family of proteins, is a negative regulator of innate immune signaling induced by the DNA sensor STING. Immunity 2014; 40: 329-341.
-
(2014)
Immunity
, vol.40
, pp. 329-341
-
-
Zhang, L.1
Mo, J.2
Swanson, K.V.3
Wen, H.4
Petrucelli, A.5
Gregory, S.M.6
-
100
-
-
84862815491
-
NLRP4 negatively regulates type i interferon signaling by targeting the kinase TBK1 for degradation via the ubiquitin ligase DTX4
-
Cui J, Li Y, Zhu L, Liu D, Songyang Z, Wang HY et al. NLRP4 negatively regulates type I interferon signaling by targeting the kinase TBK1 for degradation via the ubiquitin ligase DTX4. Nat Immunol 2012; 13: 387-395.
-
(2012)
Nat Immunol
, vol.13
, pp. 387-395
-
-
Cui, J.1
Li, Y.2
Zhu, L.3
Liu, D.4
Songyang, Z.5
Wang, H.Y.6
-
101
-
-
23844521000
-
Synergistic stimulation of human monocytes and dendritic cells by Toll-like receptor 4 and NOD1- and NOD2-activating agonists
-
Fritz JH, Girardin SE, Fitting C, Werts C, Mengin-Lecreulx D, Caroff M et al. Synergistic stimulation of human monocytes and dendritic cells by Toll-like receptor 4 and NOD1- and NOD2-activating agonists. Eur J Immunol 2005; 35: 2459-2470.
-
(2005)
Eur J Immunol
, vol.35
, pp. 2459-2470
-
-
Fritz, J.H.1
Girardin, S.E.2
Fitting, C.3
Werts, C.4
Mengin-Lecreulx, D.5
Caroff, M.6
-
102
-
-
28444471235
-
Synergistic effect of Nod1 and Nod2 agonists with toll-like receptor agonists on human dendritic cells to generate interleukin-12 and T helper type 1 cells
-
Tada H, Aiba S, Shibata K, Ohteki T, Takada H. Synergistic effect of Nod1 and Nod2 agonists with toll-like receptor agonists on human dendritic cells to generate interleukin-12 and T helper type 1 cells. Infect Immun 2005; 73: 7967-7976.
-
(2005)
Infect Immun
, vol.73
, pp. 7967-7976
-
-
Tada, H.1
Aiba, S.2
Shibata, K.3
Ohteki, T.4
Takada, H.5
-
103
-
-
84977599363
-
NOD2 and TLR2 ligands trigger the activation of basophils and eosinophils by interacting with dermal fibroblasts in atopic dermatitis-like skin inflammation
-
Jiao D, Wong CK, Qiu HN, Dong J, Cai Z, Chu M et al. NOD2 and TLR2 ligands trigger the activation of basophils and eosinophils by interacting with dermal fibroblasts in atopic dermatitis-like skin inflammation. Cell Mol Immunol 2016; 13: 535-550.
-
(2016)
Cell Mol Immunol
, vol.13
, pp. 535-550
-
-
Jiao, D.1
Wong, C.K.2
Qiu, H.N.3
Dong, J.4
Cai, Z.5
Chu, M.6
-
104
-
-
4444253690
-
NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses
-
Watanabe T, Kitani A, Murray PJ, Strober W. NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses. Nat Immunol 2004; 5: 800-808.
-
(2004)
Nat Immunol
, vol.5
, pp. 800-808
-
-
Watanabe, T.1
Kitani, A.2
Murray, P.J.3
Strober, W.4
-
105
-
-
33748493563
-
Nucleotide binding oligomerization domain 2 deficiency leads to dysregulated TLR2 signaling and induction of antigen-specific colitis
-
Watanabe T, Kitani A, Murray PJ, Wakatsuki Y, Fuss IJ, Strober W. Nucleotide binding oligomerization domain 2 deficiency leads to dysregulated TLR2 signaling and induction of antigen-specific colitis. Immunity 2006; 25: 473-485.
-
(2006)
Immunity
, vol.25
, pp. 473-485
-
-
Watanabe, T.1
Kitani, A.2
Murray, P.J.3
Wakatsuki, Y.4
Fuss, I.J.5
Strober, W.6
-
106
-
-
79959329537
-
NLRX1 negatively regulates TLR-induced NF-κB signaling by targeting TRAF6 and IKK
-
Xia X, Cui J, Wang HY, Zhu L, Matsueda S, Wang Q et al. NLRX1 negatively regulates TLR-induced NF-κB signaling by targeting TRAF6 and IKK. Immunity 2011; 34: 843-853.
-
(2011)
Immunity
, vol.34
, pp. 843-853
-
-
Xia, X.1
Cui, J.2
Wang, H.Y.3
Zhu, L.4
Matsueda, S.5
Wang, Q.6
-
107
-
-
84865404917
-
The innate immune sensor NLRC3 attenuates Toll-like receptor signaling via modification of the signaling adaptor TRAF6 and transcription factor NF-κB
-
Schneider M, Zimmermann AG, Roberts RA, Zhang L, Swanson KV, Wen H et al. The innate immune sensor NLRC3 attenuates Toll-like receptor signaling via modification of the signaling adaptor TRAF6 and transcription factor NF-κB. Nat Immunol 2012; 13: 823-831.
-
(2012)
Nat Immunol
, vol.13
, pp. 823-831
-
-
Schneider, M.1
Zimmermann, A.G.2
Roberts, R.A.3
Zhang, L.4
Swanson, K.V.5
Wen, H.6
-
108
-
-
84865130689
-
NLRP6 negatively regulates innate immunity and host defence against bacterial pathogens
-
Anand PK, Malireddi RK, Lukens JR, Vogel P, Bertin J, Lamkanfi M et al. NLRP6 negatively regulates innate immunity and host defence against bacterial pathogens. Nature 2012; 488: 389-393.
-
(2012)
Nature
, vol.488
, pp. 389-393
-
-
Anand, P.K.1
Malireddi, R.K.2
Lukens, J.R.3
Vogel, P.4
Bertin, J.5
Lamkanfi, M.6
-
109
-
-
84861460062
-
NLRP12 suppresses colon inflammation and tumorigenesis through the negative regulation of noncanonical NF-κB signaling
-
Allen IC, Wilson JE, Schneider M, Lich JD, Roberts RA, Arthur JC et al. NLRP12 suppresses colon inflammation and tumorigenesis through the negative regulation of noncanonical NF-κB signaling. Immunity 2012; 36: 742-754.
-
(2012)
Immunity
, vol.36
, pp. 742-754
-
-
Allen, I.C.1
Wilson, J.E.2
Schneider, M.3
Lich, J.D.4
Roberts, R.A.5
Arthur, J.C.6
-
110
-
-
84977560492
-
Activation of NLRC4 downregulates TLR5-mediated antibody immune responses against flagellin
-
Li W, Yang J, Zhang E, Zhong M, Xiao Y, Yu J et al. Activation of NLRC4 downregulates TLR5-mediated antibody immune responses against flagellin. Cell Mol Immunol 2016; 13: 514-523.
-
(2016)
Cell Mol Immunol
, vol.13
, pp. 514-523
-
-
Li, W.1
Yang, J.2
Zhang, E.3
Zhong, M.4
Xiao, Y.5
Yu, J.6
-
111
-
-
84961746337
-
Innate cell communication kick-starts pathogen-specific immunity
-
Rivera A, Siracusa MC, Yap GS, Gause WC. Innate cell communication kick-starts pathogen-specific immunity. Nat Immunol 2016; 17: 356-363.
-
(2016)
Nat Immunol
, vol.17
, pp. 356-363
-
-
Rivera, A.1
Siracusa, M.C.2
Yap, G.S.3
Gause, W.C.4
-
112
-
-
84988447239
-
Immune cells in term and preterm labor
-
Gomez-Lopez N, StLouis D, Lehr MA, Sanchez-Rodriguez EN, Arenas-Hernandez M. Immune cells in term and preterm labor. Cell Mol Immunol 2014; 11: 571-581.
-
(2014)
Cell Mol Immunol
, vol.11
, pp. 571-581
-
-
Gomez-Lopez, N.1
Stlouis, D.2
Lehr, M.A.3
Sanchez-Rodriguez, E.N.4
Arenas-Hernandez, M.5
-
113
-
-
84926637156
-
Respiratory epithelial cells orchestrate pulmonary innate immunity
-
Whitsett JA, Alenghat T. Respiratory epithelial cells orchestrate pulmonary innate immunity. Nat Immunol 2015; 16: 27-35.
-
(2015)
Nat Immunol
, vol.16
, pp. 27-35
-
-
Whitsett, J.A.1
Alenghat, T.2
-
115
-
-
84920506864
-
Neutrophil transcrip-tional profile changes during transit from bone marrow to sites of inflammation
-
Lakschevitz FS, Visser MB, Sun C, Glogauer M. Neutrophil transcrip-tional profile changes during transit from bone marrow to sites of inflammation. Cell Mol Immunol 2015; 12: 53-65.
-
(2015)
Cell Mol Immunol
, vol.12
, pp. 53-65
-
-
Lakschevitz, F.S.1
Visser, M.B.2
Sun, C.3
Glogauer, M.4
-
116
-
-
84891754161
-
The role of chemokines in acute and chronic hepatitis C infection
-
Fahey S, Dempsey E, Long A. The role of chemokines in acute and chronic hepatitis C infection. Cell Mol Immunol 2014; 11: 25-40.
-
(2014)
Cell Mol Immunol
, vol.11
, pp. 25-40
-
-
Fahey, S.1
Dempsey, E.2
Long, A.3
-
117
-
-
84892815323
-
Transcriptional programming of dendritic cells for enhanced MHC class II antigen presentation
-
Vander Lugt B, Khan AA, Hackney JA, Agrawal S, Lesch J, Zhou M et al. Transcriptional programming of dendritic cells for enhanced MHC class II antigen presentation. Nat Immunol 2014; 15: 161-167.
-
(2014)
Nat Immunol
, vol.15
, pp. 161-167
-
-
Vander Lugt, B.1
Khan, A.A.2
Hackney, J.A.3
Agrawal, S.4
Lesch, J.5
Zhou, M.6
-
118
-
-
84931394611
-
Identification of cDC1- and cDC2-committed DC progenitors reveals early lineage priming at the common DC progenitor stage in the bone marrow
-
Schlitzer A, Sivakamasundari V, Chen J, Sumatoh HR, Schreuder J, Lum J et al. Identification of cDC1- and cDC2-committed DC progenitors reveals early lineage priming at the common DC progenitor stage in the bone marrow. Nat Immunol 2015; 16: 718-728.
-
(2015)
Nat Immunol
, vol.16
, pp. 718-728
-
-
Schlitzer, A.1
Sivakamasundari, V.2
Chen, J.3
Sumatoh, H.R.4
Schreuder, J.5
Lum, J.6
-
119
-
-
84931406064
-
Batf3 maintains autoactivation of Irf8 for commitment of a CD8α(+) conventional DC clonogenic progenitor
-
Grajales-Reyes GE, Iwata A, Albring J, Wu X, Tussiwand R, Kc W et al. Batf3 maintains autoactivation of Irf8 for commitment of a CD8α(+) conventional DC clonogenic progenitor. Nat Immunol 2015; 16: 708-717.
-
(2015)
Nat Immunol
, vol.16
, pp. 708-717
-
-
Grajales-Reyes, G.E.1
Iwata, A.2
Albring, J.3
Wu, X.4
Tussiwand, R.5
Kc, W.6
-
120
-
-
84944903926
-
Drosha controls dendritic cell development by cleaving messenger RNAs encoding inhibitors of myelopoiesis
-
Johanson TM, Keown AA, Cmero M, Yeo JH, Kumar A, Lew AM et al. Drosha controls dendritic cell development by cleaving messenger RNAs encoding inhibitors of myelopoiesis. Nat Immunol 2015; 16: 1134-1141.
-
(2015)
Nat Immunol
, vol.16
, pp. 1134-1141
-
-
Johanson, T.M.1
Keown, A.A.2
Cmero, M.3
Yeo, J.H.4
Kumar, A.5
Lew, A.M.6
-
121
-
-
84944879733
-
Reis e Sousa C. Drosha cuts the tethers of myelopoiesis
-
Van Der Veen AG, Maillard PV. Reis e Sousa C. Drosha cuts the tethers of myelopoiesis. Nat Immunol 2015; 16: 1110-1112.
-
(2015)
Nat Immunol
, vol.16
, pp. 1110-1112
-
-
Van Der Veen, A.G.1
Maillard, P.V.2
-
122
-
-
84908146020
-
Perivascular leukocyte clusters are essential for efficient activation of effector T cells in the skin
-
Natsuaki Y, Egawa G, Nakamizo S, Ono S, Hanakawa S, Okada T et al. Perivascular leukocyte clusters are essential for efficient activation of effector T cells in the skin. Nat Immunol 2014; 15: 1064-1069.
-
(2014)
Nat Immunol
, vol.15
, pp. 1064-1069
-
-
Natsuaki, Y.1
Egawa, G.2
Nakamizo, S.3
Ono, S.4
Hanakawa, S.5
Okada, T.6
-
123
-
-
84908124353
-
Skin DCs cluster for efficient T cell activation
-
Mueller SN. Skin DCs cluster for efficient T cell activation. Nat Immunol 2014; 15: 1004-1005.
-
(2014)
Nat Immunol
, vol.15
, pp. 1004-1005
-
-
Mueller, S.N.1
-
124
-
-
84902662442
-
The atypical chemokine receptor CCRL1 shapes functional CCL21 gradients in lymph nodes
-
Ulvmar MH, Werth K, Braun A, Kelay P, Hub E, Eller K et al. The atypical chemokine receptor CCRL1 shapes functional CCL21 gradients in lymph nodes. Nat Immunol 2014; 15: 623-630.
-
(2014)
Nat Immunol
, vol.15
, pp. 623-630
-
-
Ulvmar, M.H.1
Werth, K.2
Braun, A.3
Kelay, P.4
Hub, E.5
Eller, K.6
-
125
-
-
84902653643
-
Chemokine 'grooming' by cLECs directs DC migration
-
Woodruff MC, Turley SJ. Chemokine 'grooming' by cLECs directs DC migration. Nat Immunol 2014; 15: 595-596.
-
(2014)
Nat Immunol
, vol.15
, pp. 595-596
-
-
Woodruff, M.C.1
Turley, S.J.2
-
126
-
-
85011725843
-
Absence of MHC class II on cDCs results in microbial-dependent intestinal inflammation
-
Loschko J, Schreiber HA, Rieke GJ, Esterházy D, Meredith MM, Pedicord VA et al. Absence of MHC class II on cDCs results in microbial-dependent intestinal inflammation. J Exp Med 2016; 213: 517-534.
-
(2016)
J Exp Med
, vol.213
, pp. 517-534
-
-
Loschko, J.1
Schreiber, H.A.2
Rieke, G.J.3
Esterházy, D.4
Meredith, M.M.5
Pedicord, V.A.6
-
127
-
-
84946042306
-
Differential expression of the fractalkine chemokine receptor (CX3CR1) in human monocytes during differentiation
-
Panek CA, Ramos MV, Mejias MP, Abrey-Recalde MJ, Fernandez-Brando RJ, Gori MS et al. Differential expression of the fractalkine chemokine receptor (CX3CR1) in human monocytes during differentiation. Cell Mol Immunol 2015; 12: 669-680.
-
(2015)
Cell Mol Immunol
, vol.12
, pp. 669-680
-
-
Panek, C.A.1
Ramos, M.V.2
Mejias, M.P.3
Abrey-Recalde, M.J.4
Fernandez-Brando, R.J.5
Gori, M.S.6
-
128
-
-
84896654124
-
TLR-driven early glycolytic reprogramming via the kinases TBK1-IKKϵ supports the anabolic demands of dendritic cell activation
-
Everts B, Amiel E, Huang SC, Smith AM, Chang CH, Lam WY et al. TLR-driven early glycolytic reprogramming via the kinases TBK1-IKKϵ supports the anabolic demands of dendritic cell activation. Nat Immunol 2014; 15: 323-332.
-
(2014)
Nat Immunol
, vol.15
, pp. 323-332
-
-
Everts, B.1
Amiel, E.2
Huang, S.C.3
Smith, A.M.4
Chang, C.H.5
Lam, W.Y.6
-
129
-
-
84897834053
-
Glycolytic reprogramming by TLRs in dendritic cells
-
O'Neill LA. Glycolytic reprogramming by TLRs in dendritic cells. Nat Immunol 2014; 15: 314-315.
-
(2014)
Nat Immunol
, vol.15
, pp. 314-315
-
-
O'Neill, L.A.1
-
130
-
-
84940900743
-
Regulatory dendritic cells in autoimmunity: A comprehensive review
-
Liu J, Cao X. Regulatory dendritic cells in autoimmunity: a comprehensive review. J Autoimmun 2015; 63: 1-12.
-
(2015)
J Autoimmun
, vol.63
, pp. 1-12
-
-
Liu, J.1
Cao, X.2
-
131
-
-
84925283050
-
The development and function of lung-resident macrophages and dendritic cells
-
Kopf M, Schneider C, Nobs SP. The development and function of lung-resident macrophages and dendritic cells. Nat Immunol 2015; 16: 36-44.
-
(2015)
Nat Immunol
, vol.16
, pp. 36-44
-
-
Kopf, M.1
Schneider, C.2
Nobs, S.P.3
-
132
-
-
84890987173
-
Comparative transcriptional and functional profiling defines conserved programs of intestinal DC differentiation in humans and mice
-
Watchmaker PB, Lahl K, Lee M, Baumjohann D, Morton J, Kim SJ et al. Comparative transcriptional and functional profiling defines conserved programs of intestinal DC differentiation in humans and mice. Nat Immunol 2014; 15: 98-108.
-
(2014)
Nat Immunol
, vol.15
, pp. 98-108
-
-
Watchmaker, P.B.1
Lahl, K.2
Lee, M.3
Baumjohann, D.4
Morton, J.5
Kim, S.J.6
-
133
-
-
84928897411
-
Dissecting the dendritic cell controversy in chronic hepatitis B virus infection
-
Gehring AJ, Ann D'Angelo J. Dissecting the dendritic cell controversy in chronic hepatitis B virus infection. Cell Mol Immunol 2015; 12: 283-291.
-
(2015)
Cell Mol Immunol
, vol.12
, pp. 283-291
-
-
Gehring, A.J.1
Ann D'Angelo, J.2
-
134
-
-
84928889426
-
The immune tolerant phase of chronic HBV infection: New perspectives on an old concept
-
Bertoletti A, Kennedy PT. The immune tolerant phase of chronic HBV infection: new perspectives on an old concept. Cell Mol Immunol 2015; 12: 258-263.
-
(2015)
Cell Mol Immunol
, vol.12
, pp. 258-263
-
-
Bertoletti, A.1
Kennedy, P.T.2
-
135
-
-
84936092900
-
Intratumoral dendritic cells in the anti-tumor immune response
-
Liu Y, Cao X. Intratumoral dendritic cells in the anti-tumor immune response. Cell Mol Immunol 2015; 12: 387-390.
-
(2015)
Cell Mol Immunol
, vol.12
, pp. 387-390
-
-
Liu, Y.1
Cao, X.2
-
136
-
-
84929950085
-
Thymic regulatory T cell niche size is dictated by limiting IL-2 from antigen-bearing dendritic cells and feedback competition
-
Weist BM, Kurd N, Boussier J, Chan SW, Robey EA. Thymic regulatory T cell niche size is dictated by limiting IL-2 from antigen-bearing dendritic cells and feedback competition. Nat Immunol 2015; 16: 635-641.
-
(2015)
Nat Immunol
, vol.16
, pp. 635-641
-
-
Weist, B.M.1
Kurd, N.2
Boussier, J.3
Chan, S.W.4
Robey, E.A.5
-
137
-
-
84961745271
-
Classical dendritic cells are required for dietary antigen-mediated induction of peripheral T(reg) cells and tolerance
-
Esterházy D, Loschko J, London M, Jove V, Oliveira TY, Mucida D. Classical dendritic cells are required for dietary antigen-mediated induction of peripheral T(reg) cells and tolerance. Nat Immunol 2016; 17: 545-555.
-
(2016)
Nat Immunol
, vol.17
, pp. 545-555
-
-
Esterházy, D.1
Loschko, J.2
London, M.3
Jove, V.4
Oliveira, T.Y.5
Mucida, D.6
-
138
-
-
84994633942
-
Measles virus hemagglutinin triggers intracellular signaling in CD150-expressing dendritic cells and inhibits immune response
-
e-pub ahead of print 15 June
-
Romanets-Korbut O, Kovalevska LM, Seya T, Sidorenko SP, Horvat B. Measles virus hemagglutinin triggers intracellular signaling in CD150-expressing dendritic cells and inhibits immune response. Cell Mol Immunol; e-pub ahead of print 15 June 2015; doi:10.1038/ cmi.2015.55.
-
(2015)
Cell Mol Immunol
-
-
Romanets-Korbut, O.1
Kovalevska, L.M.2
Seya, T.3
Sidorenko, S.P.4
Horvat, B.5
-
139
-
-
84905402595
-
TLR signals induce phagosomal MHC-I delivery from the endosomal recycling compartment to allow cross-presentation
-
Nair-Gupta P, Baccarini A, Tung N, Seyffer F, Florey O, Huang Y et al. TLR signals induce phagosomal MHC-I delivery from the endosomal recycling compartment to allow cross-presentation. Cell 2014; 158: 506-521.
-
(2014)
Cell
, vol.158
, pp. 506-521
-
-
Nair-Gupta, P.1
Baccarini, A.2
Tung, N.3
Seyffer, F.4
Florey, O.5
Huang, Y.6
-
140
-
-
84931578186
-
The transcription factor TFEB acts as a molecular switch that regulates exogenous antigen-presentation pathways
-
Samie M, Cresswell P. The transcription factor TFEB acts as a molecular switch that regulates exogenous antigen-presentation pathways. Nat Immunol 2015; 16: 729-736.
-
(2015)
Nat Immunol
, vol.16
, pp. 729-736
-
-
Samie, M.1
Cresswell, P.2
-
141
-
-
84894424803
-
The unfolded-protein-response sensor IRE-1α regulates the function of CD8α+ dendritic cells
-
Osorio F, Tavernier SJ, Hoffmann E, Saeys Y, Martens L, Vetters J et al. The unfolded-protein-response sensor IRE-1α regulates the function of CD8α+ dendritic cells. Nat Immunol 2014; 15: 248-257.
-
(2014)
Nat Immunol
, vol.15
, pp. 248-257
-
-
Osorio, F.1
Tavernier, S.J.2
Hoffmann, E.3
Saeys, Y.4
Martens, L.5
Vetters, J.6
-
142
-
-
84894471816
-
A new RIDDle in DC-mediated cross--presentation
-
Subramanian M, Tabas I. A new RIDDle in DC-mediated cross--presentation. Nat Immunol 2014; 15: 213-215.
-
(2014)
Nat Immunol
, vol.15
, pp. 213-215
-
-
Subramanian, M.1
Tabas, I.2
-
143
-
-
84922069715
-
Emerging functions of the unfolded protein response in immunity
-
Janssens S, Pulendran B, Lambrecht BN. Emerging functions of the unfolded protein response in immunity. Nat Immunol 2014; 15: 910-919.
-
(2014)
Nat Immunol
, vol.15
, pp. 910-919
-
-
Janssens, S.1
Pulendran, B.2
Lambrecht, B.N.3
-
144
-
-
84948172711
-
Dendritic cells require NIK for CD40-dependent cross-priming of CD8+ T cells
-
Katakam AK, Brightbill H, Franci C, Kung C, Nunez V, Jones C 3rd et al. Dendritic cells require NIK for CD40-dependent cross-priming of CD8+ T cells. Proc Natl Acad Sci USA 2015; 112: 14664-14669.
-
(2015)
Proc Natl Acad Sci USA
, vol.112
, pp. 14664-14669
-
-
Katakam, A.K.1
Brightbill, H.2
Franci, C.3
Kung, C.4
Nunez, V.5
Jones, C.6
-
145
-
-
84983490114
-
The lectin Siglec-G inhibits dendritic cell cross-presentation by impairing MHC class I-peptide complex formation
-
Ding Y, Guo Z, Liu Y, Li X, Zhang Q, Xu X et al. The lectin Siglec-G inhibits dendritic cell cross-presentation by impairing MHC class I-peptide complex formation. Nat Immunol 2016; 17: 1167-1175.
-
(2016)
Nat Immunol
, vol.17
, pp. 1167-1175
-
-
Ding, Y.1
Guo, Z.2
Liu, Y.3
Li, X.4
Zhang, Q.5
Xu, X.6
-
146
-
-
78650310810
-
The expanding family of innate lymphoid cells: Regulators and effectors of immunity and tissue remodeling
-
Spits H, Di Santo JP. The expanding family of innate lymphoid cells: regulators and effectors of immunity and tissue remodeling. Nat Immunol 2011; 12: 21-27.
-
(2011)
Nat Immunol
, vol.12
, pp. 21-27
-
-
Spits, H.1
Di Santo, J.P.2
-
147
-
-
84976336408
-
Innate lymphoid cells as regulators of immunity, inflammation and tissue homeostasis
-
Klose CS, Artis D. Innate lymphoid cells as regulators of immunity, inflammation and tissue homeostasis. Nat Immunol 2016; 17: 765-774.
-
(2016)
Nat Immunol
, vol.17
, pp. 765-774
-
-
Klose, C.S.1
Artis, D.2
-
148
-
-
84922607138
-
The biology of innate lymphoid cells
-
Artis D, Spits H. The biology of innate lymphoid cells. Nature 2015; 517: 293-301.
-
(2015)
Nature
, vol.517
, pp. 293-301
-
-
Artis, D.1
Spits, H.2
-
149
-
-
84931569282
-
Interferon-a; And interleukin 22 act synergistically for the induction of interferon-stimulated genes and control of rotavirus infection
-
Hernández PP, Mahlakõiv T, Yang I, Schwierzeck V, Nguyen N, Guendel F et al. Interferon-a; and interleukin 22 act synergistically for the induction of interferon-stimulated genes and control of rotavirus infection. Nat Immunol 2015; 16: 698-707.
-
(2015)
Nat Immunol
, vol.16
, pp. 698-707
-
-
Hernández, P.P.1
Mahlakõiv, T.2
Yang, I.3
Schwierzeck, V.4
Nguyen, N.5
Guendel, F.6
-
150
-
-
80054889051
-
Human IL-25- and IL-33-responsive type 2 innate lymphoid cells are defined by expression of CRTH2 and CD161
-
Mjösberg JM, Trifari S, Crellin NK, Peters CP, van Drunen CM, Piet B et al. Human IL-25- and IL-33-responsive type 2 innate lymphoid cells are defined by expression of CRTH2 and CD161. Nat Immunol 2011; 12: 1055-1062.
-
(2011)
Nat Immunol
, vol.12
, pp. 1055-1062
-
-
Mjósberg, J.M.1
Trifari, S.2
Crellin, N.K.3
Peters, C.P.4
Van Drunen, C.M.5
Piet, B.6
-
151
-
-
85027948313
-
Innate lymphoid cells promote lung-tissue home-ostasis after infection with influenza virus
-
Monticelli LA, Sonnenberg GF, Abt MC, Alenghat T, Ziegler CG, Doering TA et al. Innate lymphoid cells promote lung-tissue home-ostasis after infection with influenza virus. Nat Immunol 2011; 12: 1045-1054.
-
(2011)
Nat Immunol
, vol.12
, pp. 1045-1054
-
-
Monticelli, L.A.1
Sonnenberg, G.F.2
Abt, M.C.3
Alenghat, T.4
Ziegler, C.G.5
Doering, T.A.6
-
152
-
-
84983001859
-
Critical role of fatty acid metabolism in ILC2-mediated barrier protection during malnutrition and helminth infection
-
Wilhelm C, Harrison OJ, Schmitt V, Pelletier M, Spencer SP, Urban JF Jr et al. Critical role of fatty acid metabolism in ILC2-mediated barrier protection during malnutrition and helminth infection. J Exp Med 2016; 213: 1409-1418.
-
(2016)
J Exp Med
, vol.213
, pp. 1409-1418
-
-
Wilhelm, C.1
Harrison, O.J.2
Schmitt, V.3
Pelletier, M.4
Spencer, S.P.5
Urban, J.F.6
-
153
-
-
84977605156
-
G9a regulates group 2 innate lymphoid cell development by repressing the group 3 innate lymphoid cell program
-
Antignano F, Braam M, Hughes MR, Chenery AL, Burrows K, Gold MJ et al. G9a regulates group 2 innate lymphoid cell development by repressing the group 3 innate lymphoid cell program. J Exp Med 2016; 213: 1153-1162.
-
(2016)
J Exp Med
, vol.213
, pp. 1153-1162
-
-
Antignano, F.1
Braam, M.2
Hughes, M.R.3
Chenery, A.L.4
Burrows, K.5
Gold, M.J.6
-
154
-
-
84922857734
-
IL-25-responsive lineage-negative KLRG1(hi) cells are multipotential 'inflammatory' type 2 innate lymphoid cells
-
Huang Y, Guo L, Qiu J, Chen X, Hu-Li J, Siebenlist U et al. IL-25-responsive, lineage-negative KLRG1(hi) cells are multipotential 'inflammatory' type 2 innate lymphoid cells. Nat Immunol 2015; 16: 161-169.
-
(2015)
Nat Immunol
, vol.16
, pp. 161-169
-
-
Huang, Y.1
Guo, L.2
Qiu, J.3
Chen, X.4
Hu-Li, J.5
Siebenlist, U.6
-
155
-
-
84922913240
-
Inflammatory ILC2 cells: Disguising themselves as progenitors?
-
Koyasu S. Inflammatory ILC2 cells: disguising themselves as progenitors? Nat Immunol 2015; 16: 133-134.
-
(2015)
Nat Immunol
, vol.16
, pp. 133-134
-
-
Koyasu, S.1
-
156
-
-
84964300561
-
IL-1 is a critical regulator of group 2 innate lymphoid cell function and plasticity
-
Ohne Y, Silver JS, Thompson-Snipes L, Collet MA, Blanck JP, Cantarel BL et al. IL-1 is a critical regulator of group 2 innate lymphoid cell function and plasticity. Nat Immunol 2016; 17: 646-655.
-
(2016)
Nat Immunol
, vol.17
, pp. 646-655
-
-
Ohne, Y.1
Silver, J.S.2
Thompson-Snipes, L.3
Collet, M.A.4
Blanck, J.P.5
Cantarel, B.L.6
-
157
-
-
84951317601
-
Type i interferon restricts type 2 immunopathology through the regulation of group 2 innate lymphoid cells
-
Duerr CU, McCarthy CD, Mindt BC, Rubio M, Meli AP, Pothlichet J et al. Type I interferon restricts type 2 immunopathology through the regulation of group 2 innate lymphoid cells. Nat Immunol 2016; 17: 65-75.
-
(2016)
Nat Immunol
, vol.17
, pp. 65-75
-
-
Duerr, C.U.1
McCarthy, C.D.2
Mindt, B.C.3
Rubio, M.4
Meli, A.P.5
Pothlichet, J.6
-
158
-
-
84952637013
-
Group 2 innate lymphoid cells license dendritic cells to potentiate memory TH2 cell responses
-
Halim TY, Hwang YY, Scanlon ST, Zaghouani H, Garbi N, Fallon PG et al. Group 2 innate lymphoid cells license dendritic cells to potentiate memory TH2 cell responses. Nat Immunol 2016; 17: 57-64.
-
(2016)
Nat Immunol
, vol.17
, pp. 57-64
-
-
Halim, T.Y.1
Hwang, Y.Y.2
Scanlon, S.T.3
Zaghouani, H.4
Garbi, N.5
Fallon, P.G.6
-
159
-
-
84878737123
-
Innate lymphoid cells regulate CD4+ T-cell responses to intestinal commensal bacteria
-
Hepworth MR, Monticelli LA, Fung TC, Ziegler CG, Grunberg S, Sinha R et al. Innate lymphoid cells regulate CD4+ T-cell responses to intestinal commensal bacteria. Nature 2013; 498: 113-117.
-
(2013)
Nature
, vol.498
, pp. 113-117
-
-
Hepworth, M.R.1
Monticelli, L.A.2
Fung, T.C.3
Ziegler, C.G.4
Grunberg, S.5
Sinha, R.6
-
160
-
-
84896631269
-
Innate lymphoid cells integrate stromal and immunological signals to enhance antibody production by splenic marginal zone B cells
-
Magri G, Miyajima M, Bascones S, Mortha A, Puga I, Cassis L et al. Innate lymphoid cells integrate stromal and immunological signals to enhance antibody production by splenic marginal zone B cells. Nat Immunol 2014; 15: 354-364.
-
(2014)
Nat Immunol
, vol.15
, pp. 354-364
-
-
Magri, G.1
Miyajima, M.2
Bascones, S.3
Mortha, A.4
Puga, I.5
Cassis, L.6
-
161
-
-
84897859443
-
ILCs in the zone
-
Victora GD. ILCs in the zone. Nat Immunol 2014; 15: 313-314.
-
(2014)
Nat Immunol
, vol.15
, pp. 313-314
-
-
Victora, G.D.1
-
162
-
-
84923436228
-
Transcriptional programs define molecular characteristics of innate lymphoid cell classes and subsets
-
Robinette ML, Fuchs A, Cortez VS, Lee JS, Wang Y, Durum SK et al. Transcriptional programs define molecular characteristics of innate lymphoid cell classes and subsets. Nat Immunol 2015; 16: 306-317.
-
(2015)
Nat Immunol
, vol.16
, pp. 306-317
-
-
Robinette, M.L.1
Fuchs, A.2
Cortez, V.S.3
Lee, J.S.4
Wang, Y.5
Durum, S.K.6
-
163
-
-
84923525743
-
Profiling the diversity of innate lymphoid cells
-
Diefenbach A. Profiling the diversity of innate lymphoid cells. Nat Immunol 2015; 16: 222-224.
-
(2015)
Nat Immunol
, vol.16
, pp. 222-224
-
-
Diefenbach, A.1
-
164
-
-
84945461367
-
Runx3 specifies lineage commitment of innate lymphoid cells
-
Ebihara T, Song C, Ryu SH, Plougastel-Douglas B, Yang L, Levanon D et al. Runx3 specifies lineage commitment of innate lymphoid cells. Nat Immunol 2015; 16: 1124-1133.
-
(2015)
Nat Immunol
, vol.16
, pp. 1124-1133
-
-
Ebihara, T.1
Song, C.2
Ryu, S.H.3
Plougastel-Douglas, B.4
Yang, L.5
Levanon, D.6
-
165
-
-
84929899392
-
The development of innate lymphoid cells requires TOX-dependent generation of a common innate lymphoid cell progenitor
-
Seehus CR, Aliahmad P, de la Torre B, Iliev ID, Spurka L, Funari VA et al. The development of innate lymphoid cells requires TOX-dependent generation of a common innate lymphoid cell progenitor. Nat Immunol 2015; 16: 599-608.
-
(2015)
Nat Immunol
, vol.16
, pp. 599-608
-
-
Seehus, C.R.1
Aliahmad, P.2
De La Torre, B.3
Iliev, I.D.4
Spurka, L.5
Funari, V.A.6
-
166
-
-
84929891485
-
TOX sets the stage for innate lymphoid cells
-
Spits H. TOX sets the stage for innate lymphoid cells. Nat Immunol 2015; 16: 594-595.
-
(2015)
Nat Immunol
, vol.16
, pp. 594-595
-
-
Spits, H.1
-
167
-
-
84941945421
-
TCF-1 upregulation identifies early innate lymphoid progenitors in the bone marrow
-
Yang Q, Li F, Harly C, Xing S, Ye L, Xia X et al. TCF-1 upregulation identifies early innate lymphoid progenitors in the bone marrow. Nat Immunol 2015; 16: 1044-1050.
-
(2015)
Nat Immunol
, vol.16
, pp. 1044-1050
-
-
Yang, Q.1
Li, F.2
Harly, C.3
Xing, S.4
Ye, L.5
Xia, X.6
-
168
-
-
84941947672
-
ILC. Development: TCF-1 reporting
-
Kaye J ILC. development: TCF-1 reporting. in. Nat Immunol 2015; 16: 1011-1012.
-
(2015)
In Nat Immunol
, vol.16
, pp. 1011-1012
-
-
Kaye, J.1
-
169
-
-
84928887199
-
NK cell receptor imbalance and NK cell dysfunction in HBV infection and hepatocellular carcinoma
-
Sun C, Sun H, Zhang C, Tian Z. NK cell receptor imbalance and NK cell dysfunction in HBV infection and hepatocellular carcinoma. Cell Mol Immunol 2015; 12: 292-302.
-
(2015)
Cell Mol Immunol
, vol.12
, pp. 292-302
-
-
Sun, C.1
Sun, H.2
Zhang, C.3
Tian, Z.4
-
171
-
-
84939600854
-
Single-cell transcriptome analysis reveals coordinated ectopic gene-expression patterns in medullary thymic epithelial cells
-
Brennecke P, Reyes A, Pinto S, Rattay K, Nguyen M, Küchler R et al. Single-cell transcriptome analysis reveals coordinated ectopic gene-expression patterns in medullary thymic epithelial cells. Nat Immunol 2015; 16: 933-941.
-
(2015)
Nat Immunol
, vol.16
, pp. 933-941
-
-
Brennecke, P.1
Reyes, A.2
Pinto, S.3
Rattay, K.4
Nguyen, M.5
Küchler, R.6
-
172
-
-
84931424223
-
Diversity, cellular origin and autoreactivity of antibody-secreting cell population expansions in acute systemic lupus erythematosus
-
Tipton CM, Fucile CF, Darce J, Chida A, Ichikawa T, Gregoretti I et al. Diversity, cellular origin and autoreactivity of antibody-secreting cell population expansions in acute systemic lupus erythematosus. Nat Immunol 2015; 16: 755-765.
-
(2015)
Nat Immunol
, vol.16
, pp. 755-765
-
-
Tipton, C.M.1
Fucile, C.F.2
Darce, J.3
Chida, A.4
Ichikawa, T.5
Gregoretti, I.6
-
174
-
-
84937812406
-
A new mouse strain for the analysis of invariant NKT cell function
-
Chandra S, Zhao M, Budelsky A, de Mingo Pulido A, Day J, Fu Z et al. A new mouse strain for the analysis of invariant NKT cell function. Nat Immunol 2015; 16: 799-800.
-
(2015)
Nat Immunol
, vol.16
, pp. 799-800
-
-
Chandra, S.1
Zhao, M.2
Budelsky, A.3
De Mingo Pulido, A.4
Day, J.5
Fu, Z.6
-
175
-
-
84905562455
-
Negative regulation of the NLRP3 inflammasome by A20 protects against arthritis
-
Vande Walle L, Van Opdenbosch N, Jacques P, Fossoul A, Verheugen E, Vogel P et al. Negative regulation of the NLRP3 inflammasome by A20 protects against arthritis. Nature 2014; 512: 69-73.
-
(2014)
Nature
, vol.512
, pp. 69-73
-
-
Vande Walle, L.1
Van Opdenbosch, N.2
Jacques, P.3
Fossoul, A.4
Verheugen, E.5
Vogel, P.6
-
176
-
-
84941356605
-
Robust anti-viral immunity requires multiple distinct T cell-dendritic cell interactions
-
Eickhoff S, Brewitz A, Gerner MY, Klauschen F, Komander K, Hemmi H et al. Robust anti-viral immunity requires multiple distinct T cell-dendritic cell interactions. Cell 2015; 162: 1322-1337.
-
(2015)
Cell
, vol.162
, pp. 1322-1337
-
-
Eickhoff, S.1
Brewitz, A.2
Gerner, M.Y.3
Klauschen, F.4
Komander, K.5
Hemmi, H.6
-
177
-
-
84911016319
-
High-dimensional analysis of the murine myeloid cell system
-
Becher B, Schlitzer A, Chen J, Mair F, Sumatoh HR, Teng KW et al. High-dimensional analysis of the murine myeloid cell system. Nat Immunol 2014; 15: 1181-1189.
-
(2014)
Nat Immunol
, vol.15
, pp. 1181-1189
-
-
Becher, B.1
Schlitzer, A.2
Chen, J.3
Mair, F.4
Sumatoh, H.R.5
Teng, K.W.6
-
178
-
-
84928008693
-
Intravital imaging reveals how BRAF inhibition generates drug-tolerant microenvironments with high integrin β1/FAK signaling
-
Hirata E, Girotti MR, Viros A, Hooper S, Spencer-Dene B, Matsuda M et al. Intravital imaging reveals how BRAF inhibition generates drug-tolerant microenvironments with high integrin β1/FAK signaling. Cancer Cell 2015; 27: 574-588.
-
(2015)
Cancer Cell
, vol.27
, pp. 574-588
-
-
Hirata, E.1
Girotti, M.R.2
Viros, A.3
Hooper, S.4
Spencer-Dene, B.5
Matsuda, M.6
|