NLRC3, a member of the NLR family of proteins, is a negative regulator of innate immune signaling induced by the DNA sensor STING

Immunity

Volumn 40, Issue 3, 2014, Pages 329-341

  Zhang, Lu ^a,b   Mo, Jinyao ^c   Swanson, Karen V ^a   Wen, Haitao ^a   Petrucelli, Alex ^a   Gregory, Sean M ^a   Zhang, Zhigang ^a   Schneider, Monika ^c   Jiang, Yan ^d   Fitzgerald, Katherine A ^e   Ouyang, Songying ^d   Liu, Zhi Jie ^f   Damania, Blossom ^a,c   Shu, Hong Bing ^g   Duncan, Joseph A ^c   Ting, Jenny P Y ^a,c  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

^c UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^d INSTITUTE OF BIOPHYSICS   (China)

^e UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^f SHANGHAITECH UNIVERSITY   (China)

^g WUHAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; CYCLIC GMP; EXTRACHROMOSOMAL DNA; INTERFERON REGULATORY FACTOR 3; INTERLEUKIN 6; NUCLEOTIDE BINDING PROTEIN; PROTEIN NLRC3; TANK BINDING KINASE 1; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOSENSOR; CELL DEATH; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RESPONSE; CYTOSOL; DOWN REGULATION; GENE DELETION; GENE DOSAGE; HERPES SIMPLEX; HERPES SIMPLEX VIRUS 1; IMMUNOREGULATION; IN VITRO STUDY; INNATE IMMUNITY; INTERFERON PRODUCTION; MORBIDITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; SIGNAL TRANSDUCTION; STIMULATOR OF INTERFERON GENE; VIRUS LOAD;

ANIMALS; CELL LINE; CYCLIC GMP; CYTOKINES; DNA; HERPES SIMPLEX; HERPESVIRUS 1, HUMAN; HUMANS; IMMUNITY, INNATE; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; INTERFERON TYPE I; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; PROTEIN BINDING; PROTEIN TRANSPORT; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION;

EID: 84896344782     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2014.01.010     Document Type: Article

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