메뉴 건너뛰기




Volumn 141, Issue 3, 2010, Pages 483-496

NLRC5 Negatively regulates the NF-κB and type I interferon signaling pathways

Author keywords

Cellimmuno; Molimmuno; Signaling

Indexed keywords

3,4 METHYLENEDIOXYAMPHETAMINE; CASPASE RECRUITMENT DOMAIN SIGNALING PROTEIN; COMPLEMENTARY DNA; I KAPPA B KINASE; I KAPPA B KINASE ALPHA; I KAPPA B KINASE BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN LIKE RECEPTOR; RETINOIC ACID INDUCIBLE PROTEIN I; SMALL INTERFERING RNA; TOLL LIKE RECEPTOR; TUMOR NECROSIS FACTOR ALPHA; DEAD BOX PROTEIN; LIGAND; NLRC5 PROTEIN, HUMAN; NLRC5 PROTEIN, MOUSE; SIGNAL PEPTIDE;

EID: 77951902675     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cell.2010.03.040     Document Type: Article
Times cited : (365)

References (41)
  • 1
    • 32944464648 scopus 로고    scopus 로고
    • Pathogen recognition and innate immunity
    • Akira S., Uematsu S., Takeuchi O. Pathogen recognition and innate immunity. Cell 2006, 124:783-801.
    • (2006) Cell , vol.124 , pp. 783-801
    • Akira, S.1    Uematsu, S.2    Takeuchi, O.3
  • 3
    • 66149086936 scopus 로고    scopus 로고
    • NOD-like receptors: role in innate immunity and inflammatory disease
    • Chen G., Shaw M.H., Kim Y.G., Nunez G. NOD-like receptors: role in innate immunity and inflammatory disease. Annu. Rev. Pathol. 2009, 4:365-398.
    • (2009) Annu. Rev. Pathol. , vol.4 , pp. 365-398
    • Chen, G.1    Shaw, M.H.2    Kim, Y.G.3    Nunez, G.4
  • 4
    • 23144449789 scopus 로고    scopus 로고
    • Ubiquitin signalling in the NF-kappaB pathway
    • Chen Z.J. Ubiquitin signalling in the NF-kappaB pathway. Nat. Cell Biol. 2005, 7:758-765.
    • (2005) Nat. Cell Biol. , vol.7 , pp. 758-765
    • Chen, Z.J.1
  • 6
    • 43249125839 scopus 로고    scopus 로고
    • Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica
    • Dostert C., Petrilli V., Van Bruggen R., Steele C., Mossman B.T., Tschopp J. Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica. Science 2008, 320:674-677.
    • (2008) Science , vol.320 , pp. 674-677
    • Dostert, C.1    Petrilli, V.2    Van Bruggen, R.3    Steele, C.4    Mossman, B.T.5    Tschopp, J.6
  • 8
    • 45749111446 scopus 로고    scopus 로고
    • Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants
    • Eisenbarth S.C., Colegio O.R., O'Connor W., Sutterwala F.S., Flavell R.A. Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants. Nature 2008, 453:1122-1126.
    • (2008) Nature , vol.453 , pp. 1122-1126
    • Eisenbarth, S.C.1    Colegio, O.R.2    O'Connor, W.3    Sutterwala, F.S.4    Flavell, R.A.5
  • 10
    • 38849199203 scopus 로고    scopus 로고
    • Shared principles in NF-kappaB signaling
    • Hayden M.S., Ghosh S. Shared principles in NF-kappaB signaling. Cell 2008, 132:344-362.
    • (2008) Cell , vol.132 , pp. 344-362
    • Hayden, M.S.1    Ghosh, S.2
  • 11
    • 33748051738 scopus 로고    scopus 로고
    • IRFs: master regulators of signalling by Toll-like receptors and cytosolic pattern-recognition receptors
    • Honda K., Taniguchi T. IRFs: master regulators of signalling by Toll-like receptors and cytosolic pattern-recognition receptors. Nat. Rev. Immunol. 2006, 6:644-658.
    • (2006) Nat. Rev. Immunol. , vol.6 , pp. 644-658
    • Honda, K.1    Taniguchi, T.2
  • 13
    • 17644366913 scopus 로고    scopus 로고
    • NOD-LRR proteins: role in host-microbial interactions and inflammatory disease
    • Inohara N., Chamaillard M., McDonald C., Nunez G. NOD-LRR proteins: role in host-microbial interactions and inflammatory disease. Annu. Rev. Biochem. 2005, 74:355-383.
    • (2005) Annu. Rev. Biochem. , vol.74 , pp. 355-383
    • Inohara, N.1    Chamaillard, M.2    McDonald, C.3    Nunez, G.4
  • 15
    • 53349178089 scopus 로고    scopus 로고
    • STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling
    • Ishikawa H., Barber G.N. STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling. Nature 2008, 455:674-678.
    • (2008) Nature , vol.455 , pp. 674-678
    • Ishikawa, H.1    Barber, G.N.2
  • 16
    • 32944474237 scopus 로고    scopus 로고
    • Innate immunity gone awry: linking microbial infections to chronic inflammation and cancer
    • Karin M., Lawrence T., Nizet V. Innate immunity gone awry: linking microbial infections to chronic inflammation and cancer. Cell 2006, 124:823-835.
    • (2006) Cell , vol.124 , pp. 823-835
    • Karin, M.1    Lawrence, T.2    Nizet, V.3
  • 19
    • 51349108659 scopus 로고    scopus 로고
    • Negative regulation of cytoplasmic RNA-mediated antiviral signaling
    • Komuro A., Bamming D., Horvath C.M. Negative regulation of cytoplasmic RNA-mediated antiviral signaling. Cytokine 2008, 43:350-358.
    • (2008) Cytokine , vol.43 , pp. 350-358
    • Komuro, A.1    Bamming, D.2    Horvath, C.M.3
  • 20
    • 0041967054 scopus 로고    scopus 로고
    • The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination
    • Kovalenko A., Chable-Bessia C., Cantarella G., Israel A., Wallach D., Courtois G. The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination. Nature 2003, 424:801-805.
    • (2003) Nature , vol.424 , pp. 801-805
    • Kovalenko, A.1    Chable-Bessia, C.2    Cantarella, G.3    Israel, A.4    Wallach, D.5    Courtois, G.6
  • 22
    • 20644450804 scopus 로고    scopus 로고
    • Negative regulation of toll-like receptor-mediated immune responses
    • Liew F.Y., Xu D., Brint E.K., O'Neill L.A. Negative regulation of toll-like receptor-mediated immune responses. Nat. Rev. Immunol. 2005, 5:446-458.
    • (2005) Nat. Rev. Immunol. , vol.5 , pp. 446-458
    • Liew, F.Y.1    Xu, D.2    Brint, E.K.3    O'Neill, L.A.4
  • 23
    • 33646487278 scopus 로고    scopus 로고
    • Toll-like receptor 2 signaling modulates the functions of CD4+CD25+ regulatory T cells
    • Liu H., Komai-Koma M., Xu D., Liew F.Y. Toll-like receptor 2 signaling modulates the functions of CD4+CD25+ regulatory T cells. Proc. Natl. Acad. Sci. USA 2006, 103:7048-7053.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 7048-7053
    • Liu, H.1    Komai-Koma, M.2    Xu, D.3    Liew, F.Y.4
  • 24
    • 0034284715 scopus 로고    scopus 로고
    • Selective inhibition of NF-kappaB activation by a peptide that blocks the interaction of NEMO with the IkappaB kinase complex
    • May M.J., D'Acquisto F., Madge L.A., Glockner J., Pober J.S., Ghosh S. Selective inhibition of NF-kappaB activation by a peptide that blocks the interaction of NEMO with the IkappaB kinase complex. Science 2000, 289:1550-1554.
    • (2000) Science , vol.289 , pp. 1550-1554
    • May, M.J.1    D'Acquisto, F.2    Madge, L.A.3    Glockner, J.4    Pober, J.S.5    Ghosh, S.6
  • 25
    • 35349016235 scopus 로고    scopus 로고
    • Recognition of microorganisms and activation of the immune response
    • Medzhitov R. Recognition of microorganisms and activation of the immune response. Nature 2007, 449:819-826.
    • (2007) Nature , vol.449 , pp. 819-826
    • Medzhitov, R.1
  • 26
    • 33746028777 scopus 로고    scopus 로고
    • Intracellular pattern recognition receptors in the host response
    • Meylan E., Tschopp J., Karin M. Intracellular pattern recognition receptors in the host response. Nature 2006, 442:39-44.
    • (2006) Nature , vol.442 , pp. 39-44
    • Meylan, E.1    Tschopp, J.2    Karin, M.3
  • 28
    • 0035895992 scopus 로고    scopus 로고
    • Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-kappaB
    • Ogura Y., Inohara N., Benito A., Chen F.F., Yamaoka S., Nunez G. Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-kappaB. J. Biol. Chem. 2001, 276:4812-4818.
    • (2001) J. Biol. Chem. , vol.276 , pp. 4812-4818
    • Ogura, Y.1    Inohara, N.2    Benito, A.3    Chen, F.F.4    Yamaoka, S.5    Nunez, G.6
  • 31
    • 34548024379 scopus 로고    scopus 로고
    • Tumor-infiltrating gamma-delta T cells suppress T and dendritic cell function via mechanisms controlled by a unique Toll-like receptor signaling pathway
    • Peng G., Wang H.Y., Peng W., Kiniwa Y., Seo K., Wang R.-F. Tumor-infiltrating gamma-delta T cells suppress T and dendritic cell function via mechanisms controlled by a unique Toll-like receptor signaling pathway. Immunity 2007, 27:334-348.
    • (2007) Immunity , vol.27 , pp. 334-348
    • Peng, G.1    Wang, H.Y.2    Peng, W.3    Kiniwa, Y.4    Seo, K.5    Wang, R.-F.6
  • 33
    • 0032541657 scopus 로고    scopus 로고
    • IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex
    • Rothwarf D.M., Zandi E., Natoli G., Karin M. IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex. Nature 1998, 395:297-300.
    • (1998) Nature , vol.395 , pp. 297-300
    • Rothwarf, D.M.1    Zandi, E.2    Natoli, G.3    Karin, M.4
  • 35
    • 40249111682 scopus 로고    scopus 로고
    • NLRX1 is a mitochondrial NOD-like receptor that amplifies NF-kappaB and JNK pathways by inducing reactive oxygen species production
    • Tattoli I., Carneiro L.A., Jehanno M., Magalhaes J.G., Shu Y., Philpott D.J., Arnoult D., Girardin S.E. NLRX1 is a mitochondrial NOD-like receptor that amplifies NF-kappaB and JNK pathways by inducing reactive oxygen species production. EMBO Rep. 2008, 9:293-300.
    • (2008) EMBO Rep. , vol.9 , pp. 293-300
    • Tattoli, I.1    Carneiro, L.A.2    Jehanno, M.3    Magalhaes, J.G.4    Shu, Y.5    Philpott, D.J.6    Arnoult, D.7    Girardin, S.E.8
  • 36
    • 33344476398 scopus 로고    scopus 로고
    • CATERPILLERs, pyrin and hereditary immunological disorders
    • Ting J.P., Kastner D.L., Hoffman H.M. CATERPILLERs, pyrin and hereditary immunological disorders. Nat. Rev. Immunol. 2006, 6:183-195.
    • (2006) Nat. Rev. Immunol. , vol.6 , pp. 183-195
    • Ting, J.P.1    Kastner, D.L.2    Hoffman, H.M.3
  • 37
    • 0042467558 scopus 로고    scopus 로고
    • CYLD is a deubiquitinating enzyme that negatively regulates NF-kappaB activation by TNFR family members
    • Trompouki E., Hatzivassiliou E., Tsichritzis T., Farmer H., Ashworth A., Mosialos G. CYLD is a deubiquitinating enzyme that negatively regulates NF-kappaB activation by TNFR family members. Nature 2003, 424:793-796.
    • (2003) Nature , vol.424 , pp. 793-796
    • Trompouki, E.1    Hatzivassiliou, E.2    Tsichritzis, T.3    Farmer, H.4    Ashworth, A.5    Mosialos, G.6
  • 38
    • 37849014248 scopus 로고    scopus 로고
    • Toll-like receptors and immune regulation: implications for cancer therapy
    • Wang R.F., Miyahara Y., Wang H.Y. Toll-like receptors and immune regulation: implications for cancer therapy. Oncogene 2008, 27:181-189.
    • (2008) Oncogene , vol.27 , pp. 181-189
    • Wang, R.F.1    Miyahara, Y.2    Wang, H.Y.3
  • 40
    • 58049217490 scopus 로고    scopus 로고
    • RNA recognition and signal transduction by RIG-I-like receptors
    • Yoneyama M., Fujita T. RNA recognition and signal transduction by RIG-I-like receptors. Immunol. Rev. 2009, 227:54-65.
    • (2009) Immunol. Rev. , vol.227 , pp. 54-65
    • Yoneyama, M.1    Fujita, T.2
  • 41
    • 53349168904 scopus 로고    scopus 로고
    • The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation
    • Zhong B., Yang Y., Li S., Wang Y.Y., Li Y., Diao F., Lei C., He X., Zhang L., Tien P., et al. The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation. Immunity 2008, 29:538-550.
    • (2008) Immunity , vol.29 , pp. 538-550
    • Zhong, B.1    Yang, Y.2    Li, S.3    Wang, Y.Y.4    Li, Y.5    Diao, F.6    Lei, C.7    He, X.8    Zhang, L.9    Tien, P.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.