The methyltransferase Ezh2 controls cell adhesion and migration through direct methylation of the extranuclear regulatory protein talin

Nature Immunology

Volumn 16, Issue 5, 2015, Pages 505-516

  Gunawan, Merry ^a   Venkatesan, Nandini ^a   Loh, Jia Tong ^a   Wong, Jong Fu ^a   Berger, Heidi ^a   Neo, Wen Hao ^a   Li, Liang Yao Jackson ^b   La Win, Myint Khun ^a   Yau, Yin Hoe ^a   Guo, Tiannan ^a   See, Peter Chi Ee ^b   Yamazaki, Sayuri ^c   Chin, Keh Chuang ^d,e   Gingras, Alexandre R ^f   Shochat, Susana Geifman ^a   Ng, Lai Guan ^b   Sze, Siu Kwan ^a   Ginhoux, Florent ^b   Su, I Hsin ^a  

^a NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

^b AGENCY FOR SCIENCE   (Singapore)

^c NAGOYA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCES   (Japan)

^d NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^e INSTITUTE OF MOLECULAR AND CELL BIOLOGY   (Singapore)

^f UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

F ACTIN; LYSINE; PROTEIN; TALIN; TRANSCRIPTION FACTOR EZH2; UNCLASSIFIED DRUG; VAV1 PROTEIN; ACTIN; EZH2 PROTEIN, MOUSE; POLYCOMB REPRESSIVE COMPLEX 2; PROTEIN BINDING; VAV PROTEIN; VAV1 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; DENDRITIC CELL; DISEASE COURSE; FEMALE; IMMUNE RESPONSE; IN VITRO STUDY; IN VIVO STUDY; INNATE IMMUNITY; LEUKOCYTE ADHERENCE; LEUKOCYTE MIGRATION; LYMPHOCYTIC INFILTRATION; MALE; MULTIPLE SCLEROSIS; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CLEAVAGE; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN METHYLATION; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION; TRANSENDOTHELIAL AND TRANSEPITHELIAL MIGRATION; ANIMAL; CELL ADHESION; CELL CULTURE; CELL MOTION; CELL NUCLEUS; DISEASE MODEL; EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS; GENETICS; HUMAN; IMMUNOLOGY; KNOCKOUT MOUSE; LYMPHOCYTE ACTIVATION; METABOLISM; METHYLATION; MOUSE;

ACTINS; ANIMALS; CELL ADHESION; CELL MOVEMENT; CELL NUCLEUS; CELLS, CULTURED; DENDRITIC CELLS; DISEASE MODELS, ANIMAL; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; HUMANS; LYMPHOCYTE ACTIVATION; METHYLATION; MICE; MICE, KNOCKOUT; MULTIPLE SCLEROSIS; NEUTROPHILS; POLYCOMB REPRESSIVE COMPLEX 2; PROTEIN BINDING; PROTO-ONCOGENE PROTEINS C-VAV; TALIN; TRANSENDOTHELIAL AND TRANSEPITHELIAL MIGRATION;

EID: 84928570108     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.3125     Document Type: Article

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