Transcription factor Nr4a1 couples sympathetic and inflammatory cues in CNS-recruited macrophages to limit neuroinflammation

Nature Immunology

Volumn 16, Issue 12, 2015, Pages 1228-1234

  Shaked, Iftach ^a   Hanna, Richard N ^a   Shaked, Helena ^a   Chodaczek, Grzegorz ^a   Nowyhed, Heba N ^a   Tweet, George ^a   Tacke, Robert ^a   Basat, Alp Bugra ^a   Mikulski, Zbigniew ^a   Togher, Susan ^a   Miller, Jacqueline ^a   Blatchley, Amy ^a   Salek Ardakani, Shahram ^b   Darvas, Martin ^c   Kaikkonen, Minna U ^d   Thomas, Graham D ^a   Lai Wing Sun, Sonia ^e   Rezk, Ayman ^e   Bar Or, Amit ^e   Glass, Christopher K ^f   Bandukwala, Hozefa ^a   Hedrick, Catherine C ^a   more..

^a LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

^b UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^c UNIVERSITY OF WASHINGTON   (United States)

^d UNIVERSITY OF EASTERN FINLAND   (Finland)

^e MCGILL UNIVERSITY   (Canada)

^f UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENERGIC RECEPTOR BLOCKING AGENT; CATECHOLAMINE; INTERLEUKIN 6; NUCLEAR RECEPTOR NUR77; TYROSINE 3 MONOOXYGENASE; NORADRENALIN; NR4A1 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOIMMUNITY; BONE MARROW CELL; BONE MARROW DERIVED MACROPHAGE; CATECHOLAMINE SYNTHESIS; CENTRAL NERVOUS SYSTEM; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DISEASE EXACERBATION; DISEASE SEVERITY; EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS; FLOW CYTOMETRY; GRANULOCYTE; LEUKOCYTE; MACROPHAGE; MICROGLIA; MONOCYTE; MOUSE; MULTIPLE SCLEROSIS; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; T LYMPHOCYTE; THORACIC SPINAL CORD; TRANSCRIPTION INITIATION SITE; WILD TYPE; ADRENERGIC SYSTEM; ANIMAL; C57BL MOUSE; CELL CULTURE; CELL LINE; CONFOCAL MICROSCOPY; DISEASE MODEL; GENE EXPRESSION; GENETICS; HUMAN; IMMUNOLOGY; INFLAMMATION; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY; RABBIT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; CELL LINE; CELLS, CULTURED; CENTRAL NERVOUS SYSTEM; DISEASE MODELS, ANIMAL; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; GENE EXPRESSION; HUMANS; INFLAMMATION; MACROPHAGES; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROSCOPY, CONFOCAL; MULTIPLE SCLEROSIS; MYELOID CELLS; NOREPINEPHRINE; NUCLEAR RECEPTOR SUBFAMILY 4, GROUP A, MEMBER 1; RABBITS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SYMPATHETIC NERVOUS SYSTEM; TYROSINE 3-MONOOXYGENASE;

EID: 84947768583     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.3321     Document Type: Article

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