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Volumn 12, Issue 1, 2011, Pages 21-27

The expanding family of innate lymphoid cells: Regulators and effectors of immunity and tissue remodeling

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE RECEPTOR; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INHIBITOR OF DIFFERENTIATION 2; INTERLEUKIN 12; INTERLEUKIN 13; INTERLEUKIN 17; INTERLEUKIN 18; INTERLEUKIN 2 RECEPTOR GAMMA; INTERLEUKIN 22; INTERLEUKIN 25; INTERLEUKIN 33; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 7; TUMOR NECROSIS FACTOR;

EID: 78650310810     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.1962     Document Type: Review
Times cited : (696)

References (84)
  • 2
    • 0036932326 scopus 로고    scopus 로고
    • Virus-driven evolution of natural killer cell receptors
    • Arase, H. & Lanier, L.L. Virus-driven evolution of natural killer cell receptors. Microbes Infect. 4, 1505-1512 (2002).
    • (2002) Microbes Infect. , vol.4 , pp. 1505-1512
    • Arase, H.1    Lanier, L.L.2
  • 3
    • 0024792513 scopus 로고
    • Biology of natural killer cells
    • Trinchieri, G. Biology of natural killer cells. Adv. Immunol. 47, 187-376 (1989).
    • (1989) Adv. Immunol. , vol.47 , pp. 187-376
    • Trinchieri, G.1
  • 4
    • 42449116960 scopus 로고    scopus 로고
    • Natural killer cells: Diversity in search of a niche
    • Di Santo, J.P. Natural killer cells: diversity in search of a niche. Nat. Immunol. 9, 473-475 (2008).
    • (2008) Nat. Immunol. , vol.9 , pp. 473-475
    • Di Santo, J.P.1
  • 5
    • 0022589079 scopus 로고
    • The relationship of CD16 (Leu-11) and Leu-19 (NKH-1) antigen expression on human peripheral blood NK cells and cytotoxic T lymphocytes
    • Lanier, L.L., Le, A.M., Civin, C.I., Loken, M.R. & Phillips, J.H. The relationship of CD16 (Leu-11) and Leu-19 (NKH-1) antigen expression on human peripheral blood NK cells and cytotoxic T lymphocytes. J. Immunol. 136, 4480-4486 (1986).
    • (1986) J. Immunol. , vol.136 , pp. 4480-4486
    • Lanier, L.L.1    Le, A.M.2    Civin, C.I.3    Loken, M.R.4    Phillips, J.H.5
  • 6
  • 7
    • 77950408682 scopus 로고    scopus 로고
    • Regulation of human NK-cell cytokine and chemokine production by target cell recognition
    • Fauriat, C, Long, E.O., Ljunggren, H.G. & Bryceson, Y.T. Regulation of human NK-cell cytokine and chemokine production by target cell recognition. Blood 115, 2167-2176 (2010).
    • (2010) Blood , vol.115 , pp. 2167-2176
    • Fauriat, C.1    Long, E.O.2    Ljunggren, H.G.3    Bryceson, Y.T.4
  • 9
    • 33750121077 scopus 로고    scopus 로고
    • A thymic pathway of mouse natural killer cell development characterized by expression of GATA-3 and CD127
    • Vosshenrich, C.A. et al. A thymic pathway of mouse natural killer cell development characterized by expression of GATA-3 and CD127. Nat. Immunol. 7, 1217-1224 (2006).
    • (2006) Nat. Immunol. , vol.7 , pp. 1217-1224
    • Vosshenrich, C.A.1
  • 10
    • 78149490284 scopus 로고    scopus 로고
    • Thymic NK Cells develop independently from T cell precursors
    • Ribeiro, V.S. et al. Thymic NK Cells develop independently from T cell precursors. J. Immunol. 185, 4993-4997 (2010).
    • (2010) J. Immunol. , vol.185 , pp. 4993-4997
    • Ribeiro, V.S.1
  • 11
    • 34548201160 scopus 로고    scopus 로고
    • Developmental pathways that generate natural-killer-cell diversity in mice and humans
    • Huntington, N.D., Vosshenrich, C.A. & Di Santo, J.P. Developmental pathways that generate natural-killer-cell diversity in mice and humans. Nat. Rev. Immunol. 7, 703-714 (2007).
    • (2007) Nat. Rev. Immunol , vol.7 , pp. 703-714
    • Huntington, N.D.1    Vosshenrich, C.A.2    Di Santo, J.P.3
  • 12
    • 0034679718 scopus 로고    scopus 로고
    • Interferon gamma contributes to initiation of uterine vascular modifcation, decidual integrity, and uterine natural killer cell maturation during normal murine pregnancy
    • Ashkar, A.A., Di Santo, J.P. & Croy, B.A. Interferon gamma contributes to initiation of uterine vascular modifcation, decidual integrity, and uterine natural killer cell maturation during normal murine pregnancy. J. Exp. Med. 192, 259-270 (2000).
    • (2000) J. Exp. Med. , vol.192 , pp. 259-270
    • Ashkar, A.A.1    Di Santo, J.P.2    Croy, B.A.3
  • 13
    • 75649104301 scopus 로고    scopus 로고
    • The activating receptor NKp46 is essential for the development of type 1 diabetes
    • Gur, C. et al. The activating receptor NKp46 is essential for the development of type 1 diabetes. Nat. Immunol. 11, 121-128 (2010).
    • (2010) Nat. Immunol. , vol.11 , pp. 121-128
    • Gur, C.1
  • 14
    • 0030710079 scopus 로고    scopus 로고
    • + cells that can differentiate to APC NK cells, and follicular cells but not T or B cells
    • + cells that can differentiate to APC, NK cells, and follicular cells but not T or B cells. Immunity 7, 493-504 (1997).
    • (1997) Immunity , vol.7 , pp. 493-504
    • Mebius, R.E.1    Rennert, P.2    Weissman, I.L.3
  • 15
    • 0037978900 scopus 로고    scopus 로고
    • Organogenesis of lymphoid tissues
    • Mebius, R.E. Organogenesis of lymphoid tissues. Nat. Rev. Immunol. 3, 292-303 (2003).
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 292-303
    • Mebius, R.E.1
  • 16
    • 77956175900 scopus 로고    scopus 로고
    • New insights into the development of lymphoid tissues
    • van de Pavert, S.A. & Mebius, R.E. New insights into the development of lymphoid tissues. Nat. Rev. Immunol. 10, 664-674 (2010).
    • (2010) Nat. Rev. Immunol. , vol.10 , pp. 664-674
    • Van De Pavert, S.A.1    Mebius, R.E.2
  • 18
    • 0033602163 scopus 로고    scopus 로고
    • Development of peripheral lymphoid organs and natural killer cells depends on the helix-loop-helix inhibitor Id2
    • Yokota, Y. et al. Development of peripheral lymphoid organs and natural killer cells depends on the helix-loop-helix inhibitor Id2. Nature 397, 702-706 (1999).
    • (1999) Nature , vol.397 , pp. 702-706
    • Yokota, Y.1
  • 19
    • 0034733039 scopus 로고    scopus 로고
    • Requirement for RORy in thymocyte survival and lymphoid organ development
    • Sun, Z. et al. Requirement for RORy in thymocyte survival and lymphoid organ development. Science 288, 2369-2373 (2000).
    • (2000) Science , vol.288 , pp. 2369-2373
    • Sun, Z.1
  • 20
    • 0346496018 scopus 로고    scopus 로고
    • An essential function for the nuclear receptor RORy(t) in the generation of fetal lymphoid tissue inducer cells
    • Eberl, G. et al. An essential function for the nuclear receptor RORy(t) in the generation of fetal lymphoid tissue inducer cells. Nat. Immunol. 5, 64-73 (2004).
    • (2004) Nat. Immunol. , vol.5 , pp. 64-73
    • Eberl, G.1
  • 21
    • 0036906575 scopus 로고    scopus 로고
    • Different cytokines induce surface lymphotoxin-ap on IL-7 receptor - A cells that differentially engender lymph nodes and Peyer's patches
    • Yoshida, H. et al. Different cytokines induce surface lymphotoxin-ap on IL-7 receptor-a cells that differentially engender lymph nodes and Peyer's patches. Immunity 17, 823-833 (2002).
    • (2002) Immunity , vol.17 , pp. 823-833
    • Yoshida, H.1
  • 22
    • 57849131584 scopus 로고    scopus 로고
    • + natural killer-like cells
    • + natural killer-like cells. Nat. Immunol. 10, 66-74 (2009).
    • (2009) Nat. Immunol , vol.10 , pp. 66-74
    • Cupedo, T.1
  • 23
    • 70149094177 scopus 로고    scopus 로고
    • + lymphoid tissue inducer cells
    • + lymphoid tissue inducer cells. J. Immunol. 183, 2217-2221 (2009).
    • (2009) J. Immunol. , vol.183 , pp. 2217-2221
    • Schmutz, S.1
  • 24
    • 0036136321 scopus 로고    scopus 로고
    • Identifcation of multiple isolated lymphoid follicles on the antimesenteric wall of the mouse small intestine
    • Hamada, H. et al. Identifcation of multiple isolated lymphoid follicles on the antimesenteric wall of the mouse small intestine. J. Immunol. 168, 57-64 (2002).
    • (2002) J. Immunol. , vol.168 , pp. 57-64
    • Hamada, H.1
  • 25
    • 56749146467 scopus 로고    scopus 로고
    • Lymphoid tissue genesis induced by commensals through NOD1 regulates intestinal homeostasis
    • Bouskra, D. et al. Lymphoid tissue genesis induced by commensals through NOD1 regulates intestinal homeostasis. Nature 456, 507-510 (2008).
    • (2008) Nature , vol.456 , pp. 507-510
    • Bouskra, D.1
  • 26
    • 44049100259 scopus 로고    scopus 로고
    • Restoration of lymphoid organ integrity through the interaction of lymphoid tissue-inducer cells with stroma of the T cell zone
    • Scandella, E. et al. Restoration of lymphoid organ integrity through the interaction of lymphoid tissue-inducer cells with stroma of the T cell zone. Nat. Immunol. 9, 667-675 (2008).
    • (2008) Nat. Immunol , vol.9 , pp. 667-675
    • Scandella, E.1
  • 27
    • 41549135632 scopus 로고    scopus 로고
    • The biological functions of T helper 17 cell effector cytokines in infammation
    • Ouyang, W., Kolls, J.K. & Zheng, Y. The biological functions of T helper 17 cell effector cytokines in infammation. Immunity 28, 454-467 (2008).
    • (2008) Immunity , vol.28 , pp. 454-467
    • Ouyang, W.1    Kolls, J.K.2    Zheng, Y.3
  • 28
    • 60549102720 scopus 로고    scopus 로고
    • Lymphoid tissue inducer-like cells are an innate source of IL-17 and IL-22
    • Takatori, H. et al. Lymphoid tissue inducer-like cells are an innate source of IL-17 and IL-22. J. Exp. Med. 206, 35-41 (2009).
    • (2009) J. Exp. Med , vol.206 , pp. 35-41
    • Takatori, H.1
  • 29
    • 76749121875 scopus 로고    scopus 로고
    • Cyclooxygenase-1 orchestrates germinal center formation and antibody class-switch via regulation of IL-17
    • Blaho, V.A., Buczynski, M.W., Dennis, E.A. & Brown, C.R. Cyclooxygenase-1 orchestrates germinal center formation and antibody class-switch via regulation of IL-17. J. Immunol. 183, 5644-5653 (2009).
    • (2009) J. Immunol. , vol.183 , pp. 5644-5653
    • Blaho, V.A.1    Buczynski, M.W.2    Dennis, E.A.3    Brown, C.R.4
  • 30
    • 38349178776 scopus 로고    scopus 로고
    • Interleukin 17-producing T helper cells and interleukin 17 orchestrate autoreactive germinal center development in autoimmune BXD2 mice
    • Hsu, H.C. et al. Interleukin 17-producing T helper cells and interleukin 17 orchestrate autoreactive germinal center development in autoimmune BXD2 mice. Nat. Immunol. 9, 166-175 (2008).
    • (2008) Nat. Immunol , vol.9 , pp. 166-175
    • Hsu, H.C.1
  • 32
    • 48749091530 scopus 로고    scopus 로고
    • Requirement for lymphoid tissue-inducer cells in isolated follicle formation and T cell-independent immunoglobulin A generation in the gut
    • Tsuji, M. et al. Requirement for lymphoid tissue-inducer cells in isolated follicle formation and T cell-independent immunoglobulin A generation in the gut. Immunity 29, 261-271 (2008).
    • (2008) Immunity , vol.29 , pp. 261-271
    • Tsuji, M.1
  • 33
    • 50649102559 scopus 로고    scopus 로고
    • Lymphoid tissue inducer cells in adaptive CD4 T cell dependent responses
    • Lane, P. et al. Lymphoid tissue inducer cells in adaptive CD4 T cell dependent responses. Semin. Immunol. 20, 159-163 (2008).
    • (2008) Semin. Immunol , vol.20 , pp. 159-163
    • Lane, P.1
  • 34
    • 59649099774 scopus 로고    scopus 로고
    • A human natural killer cell subset provides an innate source of IL-22 for mucosal immunity
    • Cella, M. et al. A human natural killer cell subset provides an innate source of IL-22 for mucosal immunity. Nature 457, 722-725 (2009).
    • (2009) Nature , vol.457 , pp. 722-725
    • Cella, M.1
  • 35
    • 57849145994 scopus 로고    scopus 로고
    • + cell populations in gut and skin
    • + cell populations in gut and skin. Nat. Immunol. 10, 75-82 (2009).
    • (2009) Nat. Immunol , vol.10 , pp. 75-82
    • Luci, C.1
  • 37
    • 57449118239 scopus 로고    scopus 로고
    • + cells that provide innate mucosal immune defense
    • + cells that provide innate mucosal immune defense. Immunity 29, 958-970 (2008).
    • (2008) Immunity , vol.29 , pp. 958-970
    • Satoh-Takayama, N.1
  • 38
    • 77149155687 scopus 로고    scopus 로고
    • + cell subsets from Id2-dependent precursors
    • + cell subsets from Id2-dependent precursors. J. Exp. Med. 207, 273-280 (2010).
    • (2010) J. Exp. Med , vol.207 , pp. 273-280
    • Satoh-Takayama, N.1
  • 40
    • 78049385155 scopus 로고    scopus 로고
    • + innate lymphoid cells
    • + innate lymphoid cells. Science 330, 665-669 (2010).
    • (2010) Science , vol.330 , pp. 665-669
    • Sawa, S.1
  • 41
    • 40049083827 scopus 로고    scopus 로고
    • Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens
    • Zheng, Y. et al. Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens. Nat. Med. 14, 282-289 (2008).
    • (2008) Nat. Med , vol.14 , pp. 282-289
    • Zheng, Y.1
  • 42
    • 77149126766 scopus 로고    scopus 로고
    • The natural cytotoxicity receptor NKp46 is dispensable for IL-22-mediated innate intestinal immune defense against Citrobacter rodentium
    • Satoh-Takayama, N. et al. The natural cytotoxicity receptor NKp46 is dispensable for IL-22-mediated innate intestinal immune defense against Citrobacter rodentium. J. Immunol. 183, 6579-6587 (2009).
    • (2009) J. Immunol. , vol.183 , pp. 6579-6587
    • Satoh-Takayama, N.1
  • 43
    • 78650183459 scopus 로고    scopus 로고
    • + LTi-like innate lymphoid cells by Toll like receptor 2
    • doi:10.1016/j.immuni.2010.10.012 4 November
    • + LTi-like innate lymphoid cells by Toll like receptor 2. Immunity doi:10.1016/j.immuni.2010.10.012 (4 November 2010)
    • (2010) Immunity
    • Crellin, N.1
  • 44
    • 77954627022 scopus 로고    scopus 로고
    • Expansion of human NK-22 cells with IL-7 IL-2, and IL-1β reveals intrinsic functional plasticity
    • Cella, M., Otero, K. & Colonna, M. Expansion of human NK-22 cells with IL-7, IL-2, and IL-1β reveals intrinsic functional plasticity. Proc. Natl. Acad. Sci. USA 107, 10961-10966 (2010).
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 10961-10966
    • Cella, M.1    Otero, K.2    Colonna, M.3
  • 45
    • 77951878587 scopus 로고    scopus 로고
    • Innate lymphoid cells drive interleukin-23-dependent innate intestinal pathology
    • Buonocore, S. et al. Innate lymphoid cells drive interleukin-23-dependent innate intestinal pathology. Nature 464, 1371-1375 (2010).
    • (2010) Nature , vol.464 , pp. 1371-1375
    • Buonocore, S.1
  • 46
    • 18244405108 scopus 로고    scopus 로고
    • IL-25 induces IL-4 IL-5, and IL-13 and Th2-associated pathologies in vivo
    • Fort, M.M. et al. IL-25 induces IL-4, IL-5, and IL-13 and Th2-associated pathologies in vivo. Immunity 15, 985-995 (2001)
    • (2001) Immunity , vol.15 , pp. 985-995
    • Fort, M.M.1
  • 47
    • 0036644547 scopus 로고    scopus 로고
    • New IL-17 family members promote Th1 or Th2 responses in the lung: In vivo function of the novel cytokine IL-25
    • Hurst, S.D. et al. New IL-17 family members promote Th1 or Th2 responses in the lung: in vivo function of the novel cytokine IL-25. J. Immunol. 169, 443-453 (2002).
    • (2002) J. Immunol. , vol.169 , pp. 443-453
    • Hurst, S.D.1
  • 48
    • 75749122181 scopus 로고    scopus 로고
    • + lymphoid cells
    • + lymphoid cells. Nature 463, 540-544 (2010).
    • (2010) Nature , vol.463 , pp. 540-544
    • Moro, K.1
  • 49
    • 77951817855 scopus 로고    scopus 로고
    • Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity
    • Neill, D.R. et al. Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity. Nature 464, 1367-1370 (2010).
    • (2010) Nature , vol.464 , pp. 1367-1370
    • Neill, D.R.1
  • 50
    • 77951817294 scopus 로고    scopus 로고
    • H2 cytokine responses
    • H2 cytokine responses. Nature 464, 1362-1366 (2010).
    • (2010) Nature , vol.464 , pp. 1362-1366
    • Saenz, S.A.1
  • 51
    • 33645888708 scopus 로고    scopus 로고
    • Identifcation of an interleukin (IL)-25-dependent cell population that provides IL-4 IL-5, and IL-13 at the onset of helminth expulsion
    • Fallon, P.G. et al. Identifcation of an interleukin (IL)-25-dependent cell population that provides IL-4, IL-5, and IL-13 at the onset of helminth expulsion. J. Exp. Med. 203, 1105-1116 (2006).
    • (2006) J. Exp. Med. , vol.203 , pp. 1105-1116
    • Fallon, P.G.1
  • 52
    • 33645896155 scopus 로고    scopus 로고
    • Interleukin 25 regulates type 2 cytokine-dependent immunity and limits chronic infammation in the gastrointestinal tract
    • Owyang, A.M. et al. Interleukin 25 regulates type 2 cytokine-dependent immunity and limits chronic infammation in the gastrointestinal tract. J. Exp. Med. 203, 843-849 (2006).
    • (2006) J. Exp. Med. , vol.203 , pp. 843-849
    • Owyang, A.M.1
  • 53
    • 77954926597 scopus 로고    scopus 로고
    • Systemically dispersed innate IL-13-expressing cells in type 2 immunity
    • Price, A.E. et al. Systemically dispersed innate IL-13-expressing cells in type 2 immunity. Proc. Natl. Acad. Sci. USA 107, 11489-11494 (2010).
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 11489-11494
    • Price, A.E.1
  • 54
    • 0037082470 scopus 로고    scopus 로고
    • Expression of type 1 (interferon y) and type 2 (interleukin-13, interleukin-5) cytokines at distinct stages of natural killer cell differentiation from progenitor cells
    • Loza, M.J., Zamai, L, Azzoni, L, Rosati, E. & Perussia, B. Expression of type 1 (interferon y) and type 2 (interleukin-13, interleukin-5) cytokines at distinct stages of natural killer cell differentiation from progenitor cells. Blood 99, 1273-1281 (2002).
    • (2002) Blood , vol.99 , pp. 1273-1281
    • Loza, M.J.1    Zamai, L.2    Azzoni, L.3    Rosati, E.4    Perussia, B.5
  • 55
    • 56349154943 scopus 로고    scopus 로고
    • Transforming growth factor-p 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9-producing subset
    • Veldhoen, M. et al. Transforming growth factor-p 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9-producing subset. Nat. Immunol. 9, 1341-1346 (2008).
    • (2008) Nat. Immunol , vol.9 , pp. 1341-1346
    • Veldhoen, M.1
  • 56
    • 77953238901 scopus 로고    scopus 로고
    • Epigenetic instability of cytokine and transcription factor gene loci underlies plasticity of the T helper 17 cell lineage
    • Mukasa, R. et al. Epigenetic instability of cytokine and transcription factor gene loci underlies plasticity of the T helper 17 cell lineage. Immunity 32, 616-627 (2010).
    • (2010) Immunity , vol.32 , pp. 616-627
    • Mukasa, R.1
  • 58
    • 61349152914 scopus 로고    scopus 로고
    • E and ID proteins branch out
    • Kee, B.L. E and ID proteins branch out. Nat. Rev. Immunol. 9, 175-184 (2009).
    • (2009) Nat. Rev. Immunol. , vol.9 , pp. 175-184
    • Kee, B.L.1
  • 59
    • 34249014002 scopus 로고    scopus 로고
    • Mature natural killer cell and lymphoid tissue-inducing cell development requires Id2-mediated suppression of e protein activity
    • Boos, M.D., Yokota, Y., Eberl, G. & Kee, B.L. Mature natural killer cell and lymphoid tissue-inducing cell development requires Id2-mediated suppression of E protein activity. J. Exp. Med. 204, 1119-1130 (2007).
    • (2007) J. Exp. Med. , vol.204 , pp. 1119-1130
    • Boos, M.D.1    Yokota, Y.2    Eberl, G.3    Kee, B.L.4
  • 60
    • 0030665673 scopus 로고    scopus 로고
    • Inhibition of T cell and promotion of natural killer cell development by the dominant negative helix loop helix factor Id3
    • Heemskerk, M.H. et al. Inhibition of T cell and promotion of natural killer cell development by the dominant negative helix loop helix factor Id3. J. Exp. Med. 186, 1597-1602 (1997).
    • (1997) J. Exp. Med. , vol.186 , pp. 1597-1602
    • Heemskerk, M.H.1
  • 61
    • 0034684654 scopus 로고    scopus 로고
    • Id2 and Id3 inhibit development of CD34+ stem cells into predendritic cell (pre-DC)2 but not into pre-DC1. Evidence for a lymphoid origin of pre-DC2
    • Spits, H., Couwenberg, F., Bakker, A.Q., Weijer, K. & Uittenbogaart, C.H. Id2 and Id3 inhibit development of CD34+ stem cells into predendritic cell (pre-DC)2 but not into pre-DC1. Evidence for a lymphoid origin of pre-DC2. J. Exp. Med. 192, 1775-1784 (2000).
    • (2000) J. Exp. Med. , vol.192 , pp. 1775-1784
    • Spits, H.1    Couwenberg, F.2    Bakker, A.Q.3    Weijer, K.4    Uittenbogaart, C.H.5
  • 62
    • 70349446453 scopus 로고    scopus 로고
    • The basic leucine zipper transcription factor E4BP4 is essential for natural killer cell development
    • Gascoyne, D.M. et al. The basic leucine zipper transcription factor E4BP4 is essential for natural killer cell development. Nat. Immunol. 10, 1118-1124 (2009).
    • (2009) Nat. Immunol. , vol.10 , pp. 1118-1124
    • Gascoyne, D.M.1
  • 63
    • 73949134616 scopus 로고    scopus 로고
    • Nfl3/E4bp4 is required for the development and maturation of NK cells in vivo
    • Kamizono, S. et al. Nfl3/E4bp4 is required for the development and maturation of NK cells in vivo. J. Exp. Med. 206, 2977-2986 (2009).
    • (2009) J. Exp. Med. , vol.206 , pp. 2977-2986
    • Kamizono, S.1
  • 64
    • 33748588423 scopus 로고    scopus 로고
    • The orphan nuclear receptor RORyt directs the differentiation program of proinfammatory IL-17+ T helper cells
    • Ivanov, I.I. et al. The orphan nuclear receptor RORyt directs the differentiation program of proinfammatory IL-17+ T helper cells. Cell 126, 1121-1133 (2006).
    • (2006) Cell , vol.126 , pp. 1121-1133
    • Ivanov, I.I.1
  • 65
    • 42649106556 scopus 로고    scopus 로고
    • H17-cell-mediated autoimmunity to environmental toxins
    • H17-cell-mediated autoimmunity to environmental toxins. Nature 453, 106-109 (2008).
    • (2008) Nature , vol.453 , pp. 106-109
    • Veldhoen, M.1
  • 67
    • 59149105791 scopus 로고    scopus 로고
    • The suggested physiologic aryl hydrocarbon receptor activator and cytochrome P4501 substrate 6-formylindolo[3,2-b]carbazole is present in humans
    • Wincent, E. et al. The suggested physiologic aryl hydrocarbon receptor activator and cytochrome P4501 substrate 6-formylindolo[3,2-b]carbazole is present in humans. J. Biol. Chem. 284, 2690-2696 (2009).
    • (2009) J. Biol. Chem. , vol.284 , pp. 2690-2696
    • Wincent, E.1
  • 68
    • 0036194770 scopus 로고    scopus 로고
    • TOX: An HMG box protein implicated in the regulation of thymocyte selection
    • Wilkinson, B. et al. TOX: an HMG box protein implicated in the regulation of thymocyte selection. Nat. Immunol. 3, 272-280 (2002).
    • (2002) Nat. Immunol. , vol.3 , pp. 272-280
    • Wilkinson, B.1
  • 69
    • 77956963618 scopus 로고    scopus 로고
    • Shared dependence on the DNA-binding factor TOX for the development of lymphoid tissue-inducer cell and NK cell lineages
    • Aliahmad, P., de la Torre, B. & Kaye, J. Shared dependence on the DNA-binding factor TOX for the development of lymphoid tissue-inducer cell and NK cell lineages. Nat. Immunol. 11, 945-952 (2010).
    • (2010) Nat. Immunol. , vol.11 , pp. 945-952
    • Aliahmad, P.1    De La Torre, B.2    Kaye, J.3
  • 70
    • 5444239242 scopus 로고    scopus 로고
    • + T cell homeostasis
    • + T cell homeostasis. J. Exp. Med. 200, 825-834 (2004).
    • (2004) J. Exp. Med. , vol.200 , pp. 825-834
    • Burkett, P.R.1
  • 71
    • 0037460058 scopus 로고    scopus 로고
    • Interleukin (IL)-15Ra-defcient natural killer cells survive in normal but not IL-15Ra-defcient mice
    • Koka, R. et al. Interleukin (IL)-15Ra-defcient natural killer cells survive in normal but not IL-15Ra-defcient mice. J. Exp. Med. 197, 977-984 (2003).
    • (2003) J. Exp. Med. , vol.197 , pp. 977-984
    • Koka, R.1
  • 72
    • 43549096677 scopus 로고    scopus 로고
    • IL-15Ra chaperones IL-15 to stable dendritic cell membrane complexes that activate NK cells via trans presentation
    • Mortier, E., Woo, T., Advincula, R., Gozalo, S. & Ma, A. IL-15Ra chaperones IL-15 to stable dendritic cell membrane complexes that activate NK cells via trans presentation. J. Exp. Med. 205, 1213-1225 (2008).
    • (2008) J. Exp. Med. , vol.205 , pp. 1213-1225
    • Mortier, E.1    Woo, T.2    Advincula, R.3    Gozalo, S.4    Ma, A.5
  • 74
    • 60549117539 scopus 로고    scopus 로고
    • IL-15 trans-presentation promotes human NK cell development and differentiation in vivo
    • Huntington, N.D. et al. IL-15 trans-presentation promotes human NK cell development and differentiation in vivo. J. Exp. Med. 206, 25-34 (2009).
    • (2009) J. Exp. Med. , vol.206 , pp. 25-34
    • Huntington, N.D.1
  • 75
    • 20144371569 scopus 로고    scopus 로고
    • bright natural killer cells
    • bright natural killer cells. Immunity 22, 295-304 (2005).
    • (2005) Immunity , vol.22 , pp. 295-304
    • Freud, A.G.1
  • 76
    • 33645839311 scopus 로고    scopus 로고
    • Evidence for discrete stages of human natural killer cell differentiation in vivo
    • Freud, A.G. et al. Evidence for discrete stages of human natural killer cell differentiation in vivo. J. Exp. Med. 203, 1033-1043 (2006).
    • (2006) J. Exp. Med , vol.203 , pp. 1033-1043
    • Freud, A.G.1
  • 77
    • 63149141854 scopus 로고    scopus 로고
    • H17 cytokine interleukin-22
    • H17 cytokine interleukin-22. Blood 113, 4008-4010 (2009).
    • (2009) Blood , vol.113 , pp. 4008-4010
    • Hughes, T.1
  • 78
    • 77953910523 scopus 로고    scopus 로고
    • + immature human natural killer cells in secondary lymphoid tissue
    • + immature human natural killer cells in secondary lymphoid tissue. Immunity 32, 803-814 (2010).
    • (2010) Immunity , vol.32 , pp. 803-814
    • Hughes, T.1
  • 79
    • 77955890952 scopus 로고    scopus 로고
    • Interleukin-23 drives intestinal infammation through direct activity on T cells
    • Ahern, P.P. et al. Interleukin-23 drives intestinal infammation through direct activity on T cells. Immunity 33, 279-288 (2010).
    • (2010) Immunity , vol.33 , pp. 279-288
    • Ahern, P.P.1
  • 80
    • 33747089041 scopus 로고    scopus 로고
    • Differential activity of IL-12 and IL-23 in mucosal and systemic innate immune pathology
    • Uhlig, H.H. et al. Differential activity of IL-12 and IL-23 in mucosal and systemic innate immune pathology. Immunity 25, 309-318 (2006).
    • (2006) Immunity , vol.25 , pp. 309-318
    • Uhlig, H.H.1
  • 81
    • 33845340501 scopus 로고    scopus 로고
    • A genome-wide association study identifes IL23R as an infammatory bowel disease gene
    • Duerr, R.H. et al. A genome-wide association study identifes IL23R as an infammatory bowel disease gene. Science 314, 1461-1463 (2006).
    • (2006) Science , vol.314 , pp. 1461-1463
    • Duerr, R.H.1
  • 82
    • 77958153282 scopus 로고    scopus 로고
    • IL-12 initiates tumor rejection via lymphoid tissue-inducer cells bearing the natural cytotoxicity receptor NKp46
    • Eisenring, M., Vom Berg, J., Kristiansen, G., Saller, E. & Becher, B. IL-12 initiates tumor rejection via lymphoid tissue-inducer cells bearing the natural cytotoxicity receptor NKp46. Nat. Immunol. 11, 1030-1038 (2010).
    • (2010) Nat. Immunol , vol.11 , pp. 1030-1038
    • Eisenring, M.1    Vom Berg, J.2    Kristiansen, G.3    Saller, E.4    Becher, B.5
  • 83
    • 23444452087 scopus 로고    scopus 로고
    • Two sides of a cellular coin: CD4+CD3-cells regulate memory responses and lymph-node organization
    • Lane, P.J.L., Gaspal, F.M.C. & Kim, M.-Y. Two sides of a cellular coin: CD4+CD3-cells regulate memory responses and lymph-node organization. Nat. Rev. Immunol. 5, 655-660 (2005).
    • (2005) Nat. Rev. Immunol. , vol.5 , pp. 655-660
    • Lane, P.J.L.1    Gaspal, F.M.C.2    Kim, M.-Y.3
  • 84
    • 5144234518 scopus 로고    scopus 로고
    • Recognition strategies in the innate immune system of ancestral chordates
    • Khalturin, K., Panzer, Z., Cooper, M.D. & Bosch, T.C. Recognition strategies in the innate immune system of ancestral chordates. Mol. Immunol. 41, 1077-1087 (2004).
    • (2004) Mol. Immunol. , vol.41 , pp. 1077-1087
    • Khalturin, K.1    Panzer, Z.2    Cooper, M.D.3    Bosch, T.C.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.