-
1
-
-
84856111924
-
The unfolded protein response: Controlling cell fate decisions under ER stress and beyond
-
Hetz, C. The unfolded protein response: controlling cell fate decisions under ER stress and beyond. Nat. Rev. Mol. Cell Biol. 13, 89-102 (2012).
-
(2012)
Nat. Rev. Mol. Cell Biol.
, vol.13
, pp. 89-102
-
-
Hetz, C.1
-
2
-
-
34250899722
-
Signal integration in the endoplasmic reticulum unfolded protein response
-
Ron, D. & Walter, P. Signal integration in the endoplasmic reticulum unfolded protein response. Nat. Rev. Mol. Cell Biol. 8, 519-529 (2007).
-
(2007)
Nat. Rev. Mol. Cell Biol.
, vol.8
, pp. 519-529
-
-
Ron, D.1
Walter, P.2
-
3
-
-
82255173966
-
The unfolded protein response: From stress pathway to homeostatic regulation
-
Walter, P. & Ron, D. The unfolded protein response: from stress pathway to homeostatic regulation. Science 334, 1081-1086 (2011).
-
(2011)
Science
, vol.334
, pp. 1081-1086
-
-
Walter, P.1
Ron, D.2
-
4
-
-
68049110633
-
IRE1α kinase activation modes control alternate endoribonuclease outputs to determine divergent cell fates
-
Han, D. et al. IRE1α kinase activation modes control alternate endoribonuclease outputs to determine divergent cell fates. Cell 138, 562-575 (2009).
-
(2009)
Cell
, vol.138
, pp. 562-575
-
-
Han, D.1
-
5
-
-
29244448729
-
XBP-1 is required for biogenesis of cellular secretory machinery of exocrine glands
-
Lee, A.H., Chu, G.C., Iwakoshi, N.N. & Glimcher, L.H. XBP-1 is required for biogenesis of cellular secretory machinery of exocrine glands. EMBO J. 24, 4368-4380 (2005).
-
(2005)
EMBO J.
, vol.24
, pp. 4368-4380
-
-
Lee, A.H.1
Chu, G.C.2
Iwakoshi, N.N.3
Glimcher, L.H.4
-
6
-
-
3142658576
-
XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation
-
Shaffer, A.L. et al. XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation. Immunity 21, 81-93 (2004).
-
(2004)
Immunity
, vol.21
, pp. 81-93
-
-
Shaffer, A.L.1
-
7
-
-
34948897411
-
The transcription factor XBP-1 is essential for the development and survival of dendritic cells
-
Iwakoshi, N.N., Pypaert, M. & Glimcher, L.H. The transcription factor XBP-1 is essential for the development and survival of dendritic cells. J. Exp. Med. 204, 2267-2275 (2007).
-
(2007)
J. Exp. Med.
, vol.204
, pp. 2267-2275
-
-
Iwakoshi, N.N.1
Pypaert, M.2
Glimcher, L.H.3
-
8
-
-
33745893809
-
Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response
-
Hollien, J. & Weissman, J.S. Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response. Science 313, 104-107 (2006).
-
(2006)
Science
, vol.313
, pp. 104-107
-
-
Hollien, J.1
Weissman, J.S.2
-
9
-
-
68549092781
-
Regulated Ire1-dependent decay of messenger RNAs in mammalian cells
-
Hollien, J. et al. Regulated Ire1-dependent decay of messenger RNAs in mammalian cells. J. Cell Biol. 186, 323-331 (2009).
-
(2009)
J. Cell Biol.
, vol.186
, pp. 323-331
-
-
Hollien, J.1
-
10
-
-
77956016131
-
Identification of a consensus element recognized and cleaved by IRE1α
-
Oikawa, D., Tokuda, M., Hosoda, A. & Iwawaki, T. Identification of a consensus element recognized and cleaved by IRE1α. Nucleic Acids Res. 38, 6265-6273 (2010).
-
(2010)
Nucleic Acids Res.
, vol.38
, pp. 6265-6273
-
-
Oikawa, D.1
Tokuda, M.2
Hosoda, A.3
Iwawaki, T.4
-
11
-
-
84856856011
-
IRE1α activation protects mice against acetaminophen-induced hepatotoxicity
-
Hur, K.Y. et al. IRE1α activation protects mice against acetaminophen-induced hepatotoxicity. J. Exp. Med. 209, 307-318 (2012).
-
(2012)
J. Exp. Med.
, vol.209
, pp. 307-318
-
-
Hur, K.Y.1
-
13
-
-
54049110990
-
Endoplasmic reticulum stress regulator XBP-1 contributes to effector CD8+ T cell differentiation during acute infection
-
Kamimura, D. & Bevan, M.J. Endoplasmic reticulum stress regulator XBP-1 contributes to effector CD8+ T cell differentiation during acute infection. J. Immunol. 181, 5433-5441 (2008).
-
(2008)
J. Immunol.
, vol.181
, pp. 5433-5441
-
-
Kamimura, D.1
Bevan, M.J.2
-
15
-
-
1842612402
-
A transgenic mouse model for monitoring endoplasmic reticulum stress
-
Iwawaki, T., Akai, R., Kohno, K. & Miura, M. A transgenic mouse model for monitoring endoplasmic reticulum stress. Nat. Med. 10, 98-102 (2003).
-
(2003)
Nat. Med.
, vol.10
, pp. 98-102
-
-
Iwawaki, T.1
Akai, R.2
Kohno, K.3
Miura, M.4
-
16
-
-
34447275920
-
Notch-RBP-J signaling controls the homeostasis of CD8 dendritic cells in the spleen
-
Caton, M.L., Smith-Raska, M.R. & Reizis, B. Notch-RBP-J signaling controls the homeostasis of CD8 dendritic cells in the spleen. J. Exp. Med. 204, 1653-1664 (2007).
-
(2007)
J. Exp. Med.
, vol.204
, pp. 1653-1664
-
-
Caton, M.L.1
Smith-Raska, M.R.2
Reizis, B.3
-
17
-
-
45849137877
-
-
Lee, A.-H., Scapa, E.F., Cohen, D.E. & Glimcher, L.H. Regulation of hepatic lipogenesis by the transcription factor XBP Science 320, 1492-1496 (2008).
-
(2008)
Regulation of Hepatic Lipogenesis by the Transcription Factor XBP Science
, vol.320
, pp. 1492-1496
-
-
Lee, A.-H.1
Scapa, E.F.2
Cohen, D.E.3
Glimcher, L.H.4
-
18
-
-
77957085835
-
CX3CR1+ CD8α+ dendritic cells are a steady-state population related to plasmacytoid dendritic cells
-
Bar-On, L. et al. CX3CR1+ CD8α+ dendritic cells are a steady-state population related to plasmacytoid dendritic cells. Proc. Natl. Acad. Sci. USA 107, 14745-14750 (2010).
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 14745-14750
-
-
Bar-On, L.1
-
19
-
-
0033697454
-
CD40 triggering of heterodimeric IL-12 p70 production by dendritic cells in vivo requires a microbial priming signal
-
Schulz, O. et al. CD40 triggering of heterodimeric IL-12 p70 production by dendritic cells in vivo requires a microbial priming signal. Immunity 13, 453-462 (2000).
-
(2000)
Immunity
, vol.13
, pp. 453-462
-
-
Schulz, O.1
-
20
-
-
81055156202
-
A modular and combinatorial view of the antigen cross-presentation pathway in dendritic cells
-
Segura, E. & Villadangos, J.A. A modular and combinatorial view of the antigen cross-presentation pathway in dendritic cells. Traffic 12, 1677-1685 (2011).
-
(2011)
Traffic
, vol.12
, pp. 1677-1685
-
-
Segura, E.1
Villadangos, J.A.2
-
21
-
-
67249158956
-
Identification of a dendritic cell receptor that couples sensing of necrosis to immunity
-
Sancho, D. et al. Identification of a dendritic cell receptor that couples sensing of necrosis to immunity. Nature 458, 899-903 (2009).
-
(2009)
Nature
, vol.458
, pp. 899-903
-
-
Sancho, D.1
-
22
-
-
83255188884
-
Sec22b regulates phagosomal maturation and antigen crosspresentation by dendritic cells
-
Cebrian, I. et al. Sec22b regulates phagosomal maturation and antigen crosspresentation by dendritic cells. Cell 147, 1355-1368 (2011).
-
(2011)
Cell
, vol.147
, pp. 1355-1368
-
-
Cebrian, I.1
-
23
-
-
84876991539
-
Stress-independent activation of XBP1s and/or ATF6 reveals three functionally diverse ER proteostasis environments
-
Shoulders, M.D. et al. Stress-independent activation of XBP1s and/or ATF6 reveals three functionally diverse ER proteostasis environments. Cell Rep 3, 1279-1292 (2013).
-
(2013)
Cell Rep
, vol.3
, pp. 1279-1292
-
-
Shoulders, M.D.1
-
24
-
-
34250794495
-
XBP1 controls diverse cell type- and condition-specific transcriptional regulatory networks
-
Acosta-Alvear, D. et al. XBP1 controls diverse cell type- and condition-specific transcriptional regulatory networks. Mol. Cell 27, 53-66 (2007).
-
(2007)
Mol. Cell
, vol.27
, pp. 53-66
-
-
Acosta-Alvear, D.1
-
25
-
-
84874093941
-
Endoplasmic reticulum membrane reorganization is regulated by ionic homeostasis
-
Varadarajan, S. et al. Endoplasmic reticulum membrane reorganization is regulated by ionic homeostasis. PLoS ONE 8, e56603 (2013).
-
(2013)
PLoS ONE
, vol.8
-
-
Varadarajan, S.1
-
26
-
-
77958590030
-
Disruption causes histological abnormality of exocrine tissues, increase of blood glucose level, and decrease of serum immunoglobulin level
-
Iwawaki, T., Akai, R. & Kohno, K. IRE1α disruption causes histological abnormality of exocrine tissues, increase of blood glucose level, and decrease of serum immunoglobulin level. PLoS ONE 5, e13052 (2010).
-
(2010)
PLoS ONE
, vol.5
-
-
Iwawaki, T.1
Akai, R.2
Ire, K.K.3
-
27
-
-
50249116184
-
The endoplasmic reticulum stress response in immunity and autoimmunity
-
Todd, D.J., Lee, A.-H. & Glimcher, L.H. The endoplasmic reticulum stress response in immunity and autoimmunity. Nat. Rev. Immunol. 8, 663-674 (2008).
-
(2008)
Nat. Rev. Immunol.
, vol.8
, pp. 663-674
-
-
Todd, D.J.1
Lee, A.-H.2
Glimcher, L.H.3
-
28
-
-
84869395522
-
Fining the dendritic cell lineage
-
Satpathy, A.T., Wu, X., Albring, J.C. & Murphy, K.M. Re(de)fining the dendritic cell lineage. Nat. Immunol. 13, 1145-1154 (2012).
-
(2012)
Nat. Immunol.
, vol.13
, pp. 1145-1154
-
-
Satpathy, A.T.1
Wu, X.2
Albring, J.C.3
Re, M.M.K.4
-
29
-
-
69749123786
-
Fine-tuning of the unfolded protein response: Assembling the IRE1α interactome
-
Hetz, C. & Glimcher, L.H. Fine-tuning of the unfolded protein response: Assembling the IRE1α interactome. Mol. Cell 35, 551-561 (2009).
-
(2009)
Mol. Cell
, vol.35
, pp. 551-561
-
-
Hetz, C.1
Glimcher, L.H.2
-
30
-
-
70349323169
-
XBP-1-deficient plasmablasts show normal protein folding but altered glycosylation and lipid synthesis
-
McGehee, A.M. et al. XBP-1-deficient plasmablasts show normal protein folding but altered glycosylation and lipid synthesis. J. Immunol. 183, 3690-3699 (2009).
-
(2009)
J. Immunol.
, vol.183
, pp. 3690-3699
-
-
McGehee, A.M.1
-
31
-
-
67349176043
-
XBP-1 regulates signal transduction, transcription factors and bone marrow colonization in B cells
-
Hu, C.C., Dougan, S.K., McGehee, A.M., Love, J.C. & Ploegh, H.L. XBP-1 regulates signal transduction, transcription factors and bone marrow colonization in B cells. EMBO J. 28, 1624-1636 (2009).
-
(2009)
EMBO J.
, vol.28
, pp. 1624-1636
-
-
Hu, C.C.1
Dougan, S.K.2
McGehee, A.M.3
Love, J.C.4
Ploegh, H.L.5
-
32
-
-
84868628564
-
Cross-presenting CD103+ dendritic cells are protected from influenza virus infection
-
Helft, J. et al. Cross-presenting CD103+ dendritic cells are protected from influenza virus infection. J. Clin. Invest. 122, 4037-4047 (2012).
-
(2012)
J. Clin. Invest.
, vol.122
, pp. 4037-4047
-
-
Helft, J.1
-
33
-
-
76949097340
-
Quantitative proteomics reveals subset-specific viral recognition in dendritic cells
-
Luber, C.A. et al. Quantitative proteomics reveals subset-specific viral recognition in dendritic cells. Immunity 32, 279-289 (2010).
-
(2010)
Immunity
, vol.32
, pp. 279-289
-
-
Luber, C.A.1
-
34
-
-
0037120004
-
Constitutive versus activation-dependent cross-presentation of immune complexes by CD8+ and CD8 dendritic cells in vivo
-
den Haan, J.M. & Bevan, M.J. Constitutive versus activation-dependent cross-presentation of immune complexes by CD8+ and CD8 dendritic cells in vivo. J. Exp. Med. 196, 817-827 (2002).
-
(2002)
J. Exp. Med.
, vol.196
, pp. 817-827
-
-
Den Haan, J.M.1
Bevan, M.J.2
-
35
-
-
84859957011
-
F-actin is an evolutionarily conserved damage-associated molecular pattern recognized by DNGR-1, a receptor for dead cells
-
Ahrens, S. et al. F-actin is an evolutionarily conserved damage-associated molecular pattern recognized by DNGR-1, a receptor for dead cells. Immunity 36, 635-645 (2012).
-
(2012)
Immunity
, vol.36
, pp. 635-645
-
-
Ahrens, S.1
-
36
-
-
73949097613
-
Different cross-presentation pathways in steady-state and inflammatory dendritic cells
-
Segura, E., Albiston, A.L., Wicks, I.P., Chai, S.Y. & Villadangos, J.A. Different cross-presentation pathways in steady-state and inflammatory dendritic cells. Proc. Natl. Acad. Sci. USA 106, 20377-20381 (2009).
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 20377-20381
-
-
Segura, E.1
Albiston, A.L.2
Wicks, I.P.3
Chai, S.Y.4
Villadangos, J.A.5
-
37
-
-
84860007667
-
The dendritic cell receptor DNGR-1 controls endocytic handling of necrotic cell antigens to favor cross-priming of CTLs in virus-infected mice
-
Zelenay, S. et al. The dendritic cell receptor DNGR-1 controls endocytic handling of necrotic cell antigens to favor cross-priming of CTLs in virus-infected mice. J. Clin. Invest. 122, 1615-1627 (2012).
-
(2012)
J. Clin. Invest.
, vol.122
, pp. 1615-1627
-
-
Zelenay, S.1
-
38
-
-
0141707939
-
ER-phagosome fusion defines an MHC class i cross-presentation compartment in dendritic cells
-
Guermonprez, P. et al. ER-phagosome fusion defines an MHC class I cross-presentation compartment in dendritic cells. Nature 425, 397-402 (2003).
-
(2003)
Nature
, vol.425
, pp. 397-402
-
-
Guermonprez, P.1
-
39
-
-
80051989398
-
Systems biology of vaccination for seasonal influenza in humans
-
Nakaya, H.I. et al. Systems biology of vaccination for seasonal influenza in humans. Nat. Immunol. 12, 786-795 (2011).
-
(2011)
Nat. Immunol.
, vol.12
, pp. 786-795
-
-
Nakaya, H.I.1
-
40
-
-
66049108823
-
The IRE1alpha-XBP1 pathway of the unfolded protein response is required for adipogenesis
-
Sha, H. et al. The IRE1alpha-XBP1 pathway of the unfolded protein response is required for adipogenesis. Cell Metab. 9, 556-564 (2009).
-
(2009)
Cell Metab.
, vol.9
, pp. 556-564
-
-
Sha, H.1
-
41
-
-
77951290227
-
TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages
-
Martinon, F., Chen, X., Lee, A.-H. & Glimcher, L.H. TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages. Nat. Immunol. 11, 411-418 (2010).
-
(2010)
Nat. Immunol.
, vol.11
, pp. 411-418
-
-
Martinon, F.1
Chen, X.2
Lee, A.-H.3
Glimcher, L.H.4
-
42
-
-
45849137877
-
-
Lee, A.-H., Scapa, E.F., Cohen, D.E. & Glimcher, L.H. Regulation of hepatic lipogenesis by the transcription factor XBP Science 320, 1492-1496 (2008).
-
(2008)
Regulation of Hepatic Lipogenesis by the Transcription Factor XBP Science
, vol.320
, pp. 1492-1496
-
-
Lee, A.-H.1
Scapa, E.F.2
Cohen, D.E.3
Glimcher, L.H.4
|