-
1
-
-
0025883342
-
Nitric oxide: physiology, pathophysiology, and pharmacology
-
[1] Moncada, S., Palmer, R.M., Higgs, E.A., Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacol Rev 43 (1991), 109–142.
-
(1991)
Pharmacol Rev
, vol.43
, pp. 109-142
-
-
Moncada, S.1
Palmer, R.M.2
Higgs, E.A.3
-
2
-
-
0028349156
-
Nitric oxide synthases in mammals
-
[2] Knowles, R.G., Moncada, S., Nitric oxide synthases in mammals. Biochem J 298 (1994), 249–258.
-
(1994)
Biochem J
, vol.298
, pp. 249-258
-
-
Knowles, R.G.1
Moncada, S.2
-
3
-
-
33846863589
-
Nitric oxide and peroxynitrite in health and disease
-
[3] Pacher, P., Beckman, J.S., Liaudet, L., Nitric oxide and peroxynitrite in health and disease. Physiol Rev 87 (2007), 315–424.
-
(2007)
Physiol Rev
, vol.87
, pp. 315-424
-
-
Pacher, P.1
Beckman, J.S.2
Liaudet, L.3
-
4
-
-
77953752629
-
What part of NO don't you understand? Some answers to the cardinal questions in nitric oxide biology
-
[4] Hill, B.G., Dranka, B.P., Bailey, S.M., Lancaster, J.R. Jr., Darley-Usmar, V.M., What part of NO don't you understand? Some answers to the cardinal questions in nitric oxide biology. J Biol Chem 285 (2010), 19699–19704.
-
(2010)
J Biol Chem
, vol.285
, pp. 19699-19704
-
-
Hill, B.G.1
Dranka, B.P.2
Bailey, S.M.3
Lancaster, J.R.4
Darley-Usmar, V.M.5
-
5
-
-
79953762174
-
Unraveling the biological roles of reactive oxygen species
-
[5] Murphy, M.P., Holmgren, A., Larsson, N.G., Halliwell, B., Chang, C.J., Kalyanaraman, B., et al. Unraveling the biological roles of reactive oxygen species. Cell Metab 13 (2011), 361–366.
-
(2011)
Cell Metab
, vol.13
, pp. 361-366
-
-
Murphy, M.P.1
Holmgren, A.2
Larsson, N.G.3
Halliwell, B.4
Chang, C.J.5
Kalyanaraman, B.6
-
6
-
-
84878776025
-
Teaching the basics of redox biology to medical and graduate students: oxidants, antioxidants and disease mechanisms
-
[6] Kalyanaraman, B., Teaching the basics of redox biology to medical and graduate students: oxidants, antioxidants and disease mechanisms. Redox Biol 8:1 (2013), 244–257.
-
(2013)
Redox Biol
, vol.8
, Issue.1
, pp. 244-257
-
-
Kalyanaraman, B.1
-
7
-
-
84897019491
-
Nox enzymes and new thinking on reactive oxygen: a double-edged sword revisited
-
[7] Lambeth, J.D., Neish, A.S., Nox enzymes and new thinking on reactive oxygen: a double-edged sword revisited. Annu Rev Pathol 9 (2014), 119–145.
-
(2014)
Annu Rev Pathol
, vol.9
, pp. 119-145
-
-
Lambeth, J.D.1
Neish, A.S.2
-
9
-
-
0034873185
-
Reactive oxygen species as intracellular messengers during cell growth and differentiation
-
[9] Sauer, H., Wartenberg, M., Hescheler, J., Reactive oxygen species as intracellular messengers during cell growth and differentiation. Cell Physiol Biochem 11 (2001), 173–186.
-
(2001)
Cell Physiol Biochem
, vol.11
, pp. 173-186
-
-
Sauer, H.1
Wartenberg, M.2
Hescheler, J.3
-
10
-
-
0346731072
-
Nitric oxide and cell signaling: modulation of redox tone and protein modification
-
[10] Landar, A., Darley-Usmar, V.M., Nitric oxide and cell signaling: modulation of redox tone and protein modification. Amino Acids 2 (2003), 313–321.
-
(2003)
Amino Acids
, vol.2
, pp. 313-321
-
-
Landar, A.1
Darley-Usmar, V.M.2
-
11
-
-
12344312847
-
Redox signalling: from nitric oxide to oxidized lipids
-
[11] Shiva, S., Moellering, D., Ramachandran, A., Levonen, A.L., Landar, A., Venkatraman, A., et al. Redox signalling: from nitric oxide to oxidized lipids. Biochem Soc Symp 71 (2004), 107–120.
-
(2004)
Biochem Soc Symp
, vol.71
, pp. 107-120
-
-
Shiva, S.1
Moellering, D.2
Ramachandran, A.3
Levonen, A.L.4
Landar, A.5
Venkatraman, A.6
-
12
-
-
76049083966
-
Reactive oxygen species, cellular redox systems, and apoptosis
-
[12] Circu, M.L., Aw, T.Y., Reactive oxygen species, cellular redox systems, and apoptosis. Free Radic Biol Med 48 (2010), 749–762.
-
(2010)
Free Radic Biol Med
, vol.48
, pp. 749-762
-
-
Circu, M.L.1
Aw, T.Y.2
-
13
-
-
84857833776
-
Cell signalling by reactive lipid species: new concepts and molecular mechanisms
-
[13] Higdon, A., Diers, A.R., Oh, J.Y., Landar, A., Darley-Usmar, V.M., Cell signalling by reactive lipid species: new concepts and molecular mechanisms. Biochem J 442 (2012), 453–464.
-
(2012)
Biochem J
, vol.442
, pp. 453-464
-
-
Higdon, A.1
Diers, A.R.2
Oh, J.Y.3
Landar, A.4
Darley-Usmar, V.M.5
-
14
-
-
0034656849
-
Reactive oxygen species, cell signaling, and cell injury
-
[14] Hensley, K., Robinson, K.A., Gabbita, S.P., Salsman, S., Floyd, R.A., Reactive oxygen species, cell signaling, and cell injury. Free Radic Biol Med 28 (2000), 1456–1462.
-
(2000)
Free Radic Biol Med
, vol.28
, pp. 1456-1462
-
-
Hensley, K.1
Robinson, K.A.2
Gabbita, S.P.3
Salsman, S.4
Floyd, R.A.5
-
15
-
-
0034626735
-
Oxidants, oxidative stress and the biology of ageing
-
[15] Finkel, T., Holbrook, N.J., Oxidants, oxidative stress and the biology of ageing. Nature 408 (2000), 239–247.
-
(2000)
Nature
, vol.408
, pp. 239-247
-
-
Finkel, T.1
Holbrook, N.J.2
-
17
-
-
84908153270
-
Targeting antioxidants for cancer therapy
-
[17] Glasauer, A., Chandel, N.S., Targeting antioxidants for cancer therapy. Biochem Pharmacol 92 (2014), 90–101.
-
(2014)
Biochem Pharmacol
, vol.92
, pp. 90-101
-
-
Glasauer, A.1
Chandel, N.S.2
-
18
-
-
77956404377
-
Eaten alive: a history of macroautophagy
-
[18] Yang, Z., Klionsky, D.J., Eaten alive: a history of macroautophagy. Nat Cell Biol 12 (2010), 814–822.
-
(2010)
Nat Cell Biol
, vol.12
, pp. 814-822
-
-
Yang, Z.1
Klionsky, D.J.2
-
19
-
-
79251577061
-
The regulation of autophagy – unanswered questions
-
[19] Chen, Y., Klionsky, D.J., The regulation of autophagy – unanswered questions. J Cell Sci 124 (2011), 161–170.
-
(2011)
J Cell Sci
, vol.124
, pp. 161-170
-
-
Chen, Y.1
Klionsky, D.J.2
-
20
-
-
79952319773
-
Mitochondria removal by autophagy
-
[20] Wang, K., Klionsky, D.J., Mitochondria removal by autophagy. Autophagy 7 (2011), 297–300.
-
(2011)
Autophagy
, vol.7
, pp. 297-300
-
-
Wang, K.1
Klionsky, D.J.2
-
21
-
-
84891747382
-
The machinery of macroautophagy
-
[21] Feng, Y., He, D., Yao, Z., Klionsky, D.J., The machinery of macroautophagy. Cell Res 24 (2014), 24–41.
-
(2014)
Cell Res
, vol.24
, pp. 24-41
-
-
Feng, Y.1
He, D.2
Yao, Z.3
Klionsky, D.J.4
-
22
-
-
84866122688
-
Autophagy modulation as a potential therapeutic target for diverse diseases
-
[22] Rubinsztein, D.C., Codogno, P., Levine, B., Autophagy modulation as a potential therapeutic target for diverse diseases. Nat Rev Drug Discov 11 (2012), 709–730.
-
(2012)
Nat Rev Drug Discov
, vol.11
, pp. 709-730
-
-
Rubinsztein, D.C.1
Codogno, P.2
Levine, B.3
-
23
-
-
84861526009
-
Deconvoluting the context-dependent role for autophagy in cancer
-
[23] White, E., Deconvoluting the context-dependent role for autophagy in cancer. Nat Rev Cancer 12 (2012), 401–410.
-
(2012)
Nat Rev Cancer
, vol.12
, pp. 401-410
-
-
White, E.1
-
24
-
-
84555195856
-
Autophagy, mitochondria and oxidative stress: cross-talk and redox signalling
-
[24] Lee, J., Giordano, S., Zhang, J., Autophagy, mitochondria and oxidative stress: cross-talk and redox signalling. Biochem J 441 (2012), 523–540.
-
(2012)
Biochem J
, vol.441
, pp. 523-540
-
-
Lee, J.1
Giordano, S.2
Zhang, J.3
-
25
-
-
84869388804
-
Integration of cellular bioenergetics with mitochondrial quality control and autophagy
-
[25] Hill, B.G., Benavides, G.A., Lancaster, J.R. Jr., Ballinger, S., Dell'Italia, L., Jianhua, Z., et al. Integration of cellular bioenergetics with mitochondrial quality control and autophagy. Biol Chem 393 (2012), 1485–1512.
-
(2012)
Biol Chem
, vol.393
, pp. 1485-1512
-
-
Hill, B.G.1
Benavides, G.A.2
Lancaster, J.R.3
Ballinger, S.4
Dell'Italia, L.5
Jianhua, Z.6
-
26
-
-
84877628647
-
Autophagy in human health and disease
-
[26] Choi, A.M., Ryter, S.W., Levine, B., Autophagy in human health and disease. N Engl J Med 368 (2013), 1845–1846.
-
(2013)
N Engl J Med
, vol.368
, pp. 1845-1846
-
-
Choi, A.M.1
Ryter, S.W.2
Levine, B.3
-
27
-
-
84875892111
-
Autophagy as a stress-response and quality-control mechanism: implications for cell injury and human disease
-
[27] Murrow, L., Debnath, J., Autophagy as a stress-response and quality-control mechanism: implications for cell injury and human disease. Annu Rev Pathol 8 (2013), 105–137.
-
(2013)
Annu Rev Pathol
, vol.8
, pp. 105-137
-
-
Murrow, L.1
Debnath, J.2
-
28
-
-
84892163616
-
Autophagy as an essential cellular antioxidant pathway in neurodegenerative disease
-
[28] Giordano, S., Darley-Usmar, V., Zhang, J., Autophagy as an essential cellular antioxidant pathway in neurodegenerative disease. Redox Biol 2 (2013), 82–90.
-
(2013)
Redox Biol
, vol.2
, pp. 82-90
-
-
Giordano, S.1
Darley-Usmar, V.2
Zhang, J.3
-
29
-
-
84879475204
-
Autophagy and mitophagy in cellular damage control
-
[29] Zhang, J., Autophagy and mitophagy in cellular damage control. Redox Biol 1 (2013), 19–23.
-
(2013)
Redox Biol
, vol.1
, pp. 19-23
-
-
Zhang, J.1
-
30
-
-
84879047011
-
Cellular metabolic and autophagic pathways: traffic control by redox signaling
-
[30] Dodson, M., Darley-Usmar, V., Zhang, J., Cellular metabolic and autophagic pathways: traffic control by redox signaling. Free Radic Biol Med 63 (2013), 207–221.
-
(2013)
Free Radic Biol Med
, vol.63
, pp. 207-221
-
-
Dodson, M.1
Darley-Usmar, V.2
Zhang, J.3
-
31
-
-
84898785937
-
Redox regulation of antioxidants, autophagy, and the response to stress: implications for electrophile therapeutics
-
[31] Levonen, A.L., Hill, B.G., Kansanen, E., Zhang, J., Darley-Usmar, V.M., Redox regulation of antioxidants, autophagy, and the response to stress: implications for electrophile therapeutics. Free Radic Biol Med 71 (2014), 196–207.
-
(2014)
Free Radic Biol Med
, vol.71
, pp. 196-207
-
-
Levonen, A.L.1
Hill, B.G.2
Kansanen, E.3
Zhang, J.4
Darley-Usmar, V.M.5
-
32
-
-
84901768886
-
Mitophagy mechanisms and role in human diseases
-
[32] Redmann, M., Dodson, M., Boyer-Guittaut, M., Darley-Usmar, V., Zhang, J., Mitophagy mechanisms and role in human diseases. Int J Biochem Cell Biol 53 (2014), 127–133.
-
(2014)
Int J Biochem Cell Biol
, vol.53
, pp. 127-133
-
-
Redmann, M.1
Dodson, M.2
Boyer-Guittaut, M.3
Darley-Usmar, V.4
Zhang, J.5
-
33
-
-
84921459109
-
Aging and energetics' 'Top 40' future research opportunities 2010–2013
-
[33] Allison, D.B., Antoine, L.H., Ballinger, S.W., Bamman, M.M., Biga, P., Darley-Usmar, V.M., et al. Aging and energetics' 'Top 40' future research opportunities 2010–2013. F1000Res, 3, 2014, 219.
-
(2014)
F1000Res
, vol.3
, pp. 219
-
-
Allison, D.B.1
Antoine, L.H.2
Ballinger, S.W.3
Bamman, M.M.4
Biga, P.5
Darley-Usmar, V.M.6
-
34
-
-
0027247805
-
Oxidants in cigarette smoke. Radicals, hydrogen peroxide, peroxynitrate, and peroxynitrite
-
[34] Pryor, W.A., Stone, K., Oxidants in cigarette smoke. Radicals, hydrogen peroxide, peroxynitrate, and peroxynitrite. Ann N Y Acad Sci 686 (1993), 12–27.
-
(1993)
Ann N Y Acad Sci
, vol.686
, pp. 12-27
-
-
Pryor, W.A.1
Stone, K.2
-
35
-
-
0027940508
-
Molecular mechanisms of damage by excess nitrogen oxides: nitration of tyrosine by gas-phase cigarette smoke
-
[35] Eiserich, J.P., Vossen, V., O'Neill, C.A., Halliwell, B., Cross, C.E., van der Vliet, A., Molecular mechanisms of damage by excess nitrogen oxides: nitration of tyrosine by gas-phase cigarette smoke. FEBS Lett 353 (1994), 53–56.
-
(1994)
FEBS Lett
, vol.353
, pp. 53-56
-
-
Eiserich, J.P.1
Vossen, V.2
O'Neill, C.A.3
Halliwell, B.4
Cross, C.E.5
van der Vliet, A.6
-
36
-
-
0029886786
-
Cancer risk and oxidative DNA damage in man
-
[36] Loft, S., Poulsen, H.E., Cancer risk and oxidative DNA damage in man. J Mol Med Berl 74 (1996), 297–312.
-
(1996)
J Mol Med Berl
, vol.74
, pp. 297-312
-
-
Loft, S.1
Poulsen, H.E.2
-
37
-
-
8444234762
-
Tobacco smoking and cancer: a brief review of recent epidemiological evidence
-
[37] Sasco, A.J., Secretan, M.B., Straif, K., Tobacco smoking and cancer: a brief review of recent epidemiological evidence. Lung Cancer 45 (2004), S3–S9.
-
(2004)
Lung Cancer
, vol.45
, pp. S3-S9
-
-
Sasco, A.J.1
Secretan, M.B.2
Straif, K.3
-
38
-
-
0030980641
-
Mitogenic signaling mediated by oxidants in Ras-transformed fibroblasts
-
[38] Irani, K., Xia, Y., Zweier, J.L., Sollott, S.J., Der, C.J., Fearon, E.R., et al. Mitogenic signaling mediated by oxidants in Ras-transformed fibroblasts. Science 275 (1997), 1649–1652.
-
(1997)
Science
, vol.275
, pp. 1649-1652
-
-
Irani, K.1
Xia, Y.2
Zweier, J.L.3
Sollott, S.J.4
Der, C.J.5
Fearon, E.R.6
-
39
-
-
0032499395
-
Ras, superoxide and signal transduction
-
[39] Irani, K., Goldschmidt-Clermont, P.J., Ras, superoxide and signal transduction. Biochem Pharmacol 55 (1998), 1339–1346.
-
(1998)
Biochem Pharmacol
, vol.55
, pp. 1339-1346
-
-
Irani, K.1
Goldschmidt-Clermont, P.J.2
-
40
-
-
0036285034
-
c-Myc can induce DNA damage, increase reactive oxygen species, and mitigate p53 function: a mechanism for oncogene-induced genetic instability
-
[40] Vafa, O., Wade, M., Kern, S., Beeche, M., Pandita, T.K., Hampton, G.M., et al. c-Myc can induce DNA damage, increase reactive oxygen species, and mitigate p53 function: a mechanism for oncogene-induced genetic instability. Mol Cell 9 (2002), 1031–1044.
-
(2002)
Mol Cell
, vol.9
, pp. 1031-1044
-
-
Vafa, O.1
Wade, M.2
Kern, S.3
Beeche, M.4
Pandita, T.K.5
Hampton, G.M.6
-
41
-
-
77952737658
-
Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity
-
[41] Weinberg, F., Hamanaka, R., Wheaton, W.W., Weinberg, S., Joseph, J., Lopez, M., et al. Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity. Proc Natl Acad Sci USA 107 (2010), 8788–8793.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 8788-8793
-
-
Weinberg, F.1
Hamanaka, R.2
Wheaton, W.W.3
Weinberg, S.4
Joseph, J.5
Lopez, M.6
-
42
-
-
79959969874
-
Glioma stem cell proliferation and tumor growth are promoted by nitric oxide synthase-2
-
[42] Eyler, C.E., Wu, Q., Yan, K., MacSwords, J.M., Chandler-Militello, D., Misuraca, K.L., et al. Glioma stem cell proliferation and tumor growth are promoted by nitric oxide synthase-2. Cell 146 (2011), 53–66.
-
(2011)
Cell
, vol.146
, pp. 53-66
-
-
Eyler, C.E.1
Wu, Q.2
Yan, K.3
MacSwords, J.M.4
Chandler-Militello, D.5
Misuraca, K.L.6
-
43
-
-
75349091751
-
Perivascular nitric oxide activates notch signaling and promotes stem-like character in PDGF-induced glioma cells
-
[43] Charles, N., Ozawa, T., Squatrito, M., Bleau, A.M., Brennan, C.W., Hambardzumyan, D., et al. Perivascular nitric oxide activates notch signaling and promotes stem-like character in PDGF-induced glioma cells. Cell Stem Cell 6 (2010), 141–152.
-
(2010)
Cell Stem Cell
, vol.6
, pp. 141-152
-
-
Charles, N.1
Ozawa, T.2
Squatrito, M.3
Bleau, A.M.4
Brennan, C.W.5
Hambardzumyan, D.6
-
44
-
-
84899655872
-
Tumor microenvironment-based feed-forward regulation of NOS2 in breast cancer progression
-
[44] Heinecke, J.L., Ridnour, L.A., Cheng, R.Y., Switzer, C.H., Lizardo, M.M., Khanna, C., et al. Tumor microenvironment-based feed-forward regulation of NOS2 in breast cancer progression. Proc Natl Acad Sci USA 111 (2014), 6323–6328.
-
(2014)
Proc Natl Acad Sci USA
, vol.111
, pp. 6323-6328
-
-
Heinecke, J.L.1
Ridnour, L.A.2
Cheng, R.Y.3
Switzer, C.H.4
Lizardo, M.M.5
Khanna, C.6
-
45
-
-
78049426509
-
Increased NOS2 predicts poor survival in estrogen receptor-negative breast cancer patients
-
[45] Glynn, S.A., Boersma, B.J., Dorsey, T.H., Yi, M., Yfantis, H.G., Ridnour, L.A., et al. Increased NOS2 predicts poor survival in estrogen receptor-negative breast cancer patients. J Clin Invest 120 (2010), 3843–3854.
-
(2010)
J Clin Invest
, vol.120
, pp. 3843-3854
-
-
Glynn, S.A.1
Boersma, B.J.2
Dorsey, T.H.3
Yi, M.4
Yfantis, H.G.5
Ridnour, L.A.6
-
46
-
-
84937523330
-
High nitric oxide production, secondary to inducible nitric oxide synthase expression, is essential for regulation of the tumour-initiating properties of colon cancer stem cells
-
[46] Puglisi, M.A., Cenciarelli, C., Tesori, V., Cappellari, M., Martini, M., Di Francesco, A.M., et al. High nitric oxide production, secondary to inducible nitric oxide synthase expression, is essential for regulation of the tumour-initiating properties of colon cancer stem cells. J Pathol 236 (2015), 479–490.
-
(2015)
J Pathol
, vol.236
, pp. 479-490
-
-
Puglisi, M.A.1
Cenciarelli, C.2
Tesori, V.3
Cappellari, M.4
Martini, M.5
Di Francesco, A.M.6
-
47
-
-
28644447272
-
The antioxidant function of the p53 tumor suppressor
-
[47] Sablina, A.A., Budanov, A.V., Ilyinskaya, G.V., Agapova, L.S., Kravchenko, J.E., Chumakov, P.M., The antioxidant function of the p53 tumor suppressor. Nat Med 11 (2005), 1306–1313.
-
(2005)
Nat Med
, vol.11
, pp. 1306-1313
-
-
Sablina, A.A.1
Budanov, A.V.2
Ilyinskaya, G.V.3
Agapova, L.S.4
Kravchenko, J.E.5
Chumakov, P.M.6
-
48
-
-
84861973567
-
Tumor suppression in the absence of p53-mediated cell-cycle arrest, apoptosis, and senescence
-
[48] Li, T., Kon, N., Jiang, L., Tan, M., Ludwig, T., Zhao, Y., et al. Tumor suppression in the absence of p53-mediated cell-cycle arrest, apoptosis, and senescence. Cell 149 (2012), 1269–1283.
-
(2012)
Cell
, vol.149
, pp. 1269-1283
-
-
Li, T.1
Kon, N.2
Jiang, L.3
Tan, M.4
Ludwig, T.5
Zhao, Y.6
-
49
-
-
0035853157
-
Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice
-
[49] Ramos-Gomez, M., Kwak, M.K., Dolan, P.M., Itoh, K., Yamamoto, M., Talalay, P., et al. Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice. Proc Natl Acad Sci USA 98 (2001), 3410–3415.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 3410-3415
-
-
Ramos-Gomez, M.1
Kwak, M.K.2
Dolan, P.M.3
Itoh, K.4
Yamamoto, M.5
Talalay, P.6
-
50
-
-
4644328941
-
Nrf2 is essential for the chemopreventive efficacy of oltipraz against urinary bladder carcinogenesis
-
[50] Iida, K., Itoh, K., Kumagai, Y., Oyasu, R., Hattori, K., Kawai, K., et al. Nrf2 is essential for the chemopreventive efficacy of oltipraz against urinary bladder carcinogenesis. Cancer Res 64 (2004), 6424–6431.
-
(2004)
Cancer Res
, vol.64
, pp. 6424-6431
-
-
Iida, K.1
Itoh, K.2
Kumagai, Y.3
Oyasu, R.4
Hattori, K.5
Kawai, K.6
-
51
-
-
33748089664
-
Inhibition of 7,12-dimethylbenz(a)anthracene-induced skin tumorigenesis in C57BL/6 mice by sulforaphane is mediated by nuclear factor E2-related factor 2
-
[51] Xu, C., Huang, M.T., Shen, G., Yuan, X., Lin, W., Khor, T.O., et al. Inhibition of 7,12-dimethylbenz(a)anthracene-induced skin tumorigenesis in C57BL/6 mice by sulforaphane is mediated by nuclear factor E2-related factor 2. Cancer Res 66 (2006), 8293–8296.
-
(2006)
Cancer Res
, vol.66
, pp. 8293-8296
-
-
Xu, C.1
Huang, M.T.2
Shen, G.3
Yuan, X.4
Lin, W.5
Khor, T.O.6
-
52
-
-
33644537902
-
Potent protection against aflatoxin-induced tumorigenesis through induction of Nrf2-regulated pathways by the triterpenoid 1-[2-cyano-3-,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole
-
[52] Yates, M.S., Kwak, M.K., Egner, P.A., Groopman, J.D., Bodreddigari, S., Sutter, T.R., et al. Potent protection against aflatoxin-induced tumorigenesis through induction of Nrf2-regulated pathways by the triterpenoid 1-[2-cyano-3-,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole. Cancer Res 66 (2006), 2488–2494.
-
(2006)
Cancer Res
, vol.66
, pp. 2488-2494
-
-
Yates, M.S.1
Kwak, M.K.2
Egner, P.A.3
Groopman, J.D.4
Bodreddigari, S.5
Sutter, T.R.6
-
53
-
-
84890441806
-
Nrf2 knockout enhances intestinal tumorigenesis in Apc(min/+) mice due to attenuation of anti-oxidative stress pathway while potentiates inflammation
-
[53] Cheung, K.L., Lee, J.H., Khor, T.O., Wu, T.Y., Li, G.X., Chan, J., et al. Nrf2 knockout enhances intestinal tumorigenesis in Apc(min/+) mice due to attenuation of anti-oxidative stress pathway while potentiates inflammation. Mol Carcinog 53 (2014), 77–84.
-
(2014)
Mol Carcinog
, vol.53
, pp. 77-84
-
-
Cheung, K.L.1
Lee, J.H.2
Khor, T.O.3
Wu, T.Y.4
Li, G.X.5
Chan, J.6
-
54
-
-
56249086316
-
Increased susceptibility of Nrf2 knockout mice to colitis-associated colorectal cancer
-
[54] Khor, T.O., Huang, M.T., Prawan, A., Liu, Y., Hao, X., Yu, S., et al. Increased susceptibility of Nrf2 knockout mice to colitis-associated colorectal cancer. Cancer Prev Res (Phila) 1 (2008), 187–191.
-
(2008)
Cancer Prev Res (Phila)
, vol.1
, pp. 187-191
-
-
Khor, T.O.1
Huang, M.T.2
Prawan, A.3
Liu, Y.4
Hao, X.5
Yu, S.6
-
55
-
-
56649083534
-
Dual roles of Nrf2 in cancer
-
[55] Lau, A., Villeneuve, N.F., Sun, Z., Wong, P.K., Zhang, D.D., Dual roles of Nrf2 in cancer. Pharmacol Res 58 (2008), 262–270.
-
(2008)
Pharmacol Res
, vol.58
, pp. 262-270
-
-
Lau, A.1
Villeneuve, N.F.2
Sun, Z.3
Wong, P.K.4
Zhang, D.D.5
-
56
-
-
84864348569
-
NRF2 and cancer: the good, the bad and the importance of context
-
[56] Sporn, M.B., Liby, K.T., NRF2 and cancer: the good, the bad and the importance of context. Nat Rev Cancer 12 (2012), 564–571.
-
(2012)
Nat Rev Cancer
, vol.12
, pp. 564-571
-
-
Sporn, M.B.1
Liby, K.T.2
-
57
-
-
79960060305
-
Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis
-
[57] DeNicola, G.M., Karreth, F.A., Humpton, T.J., Gopinathan, A., Wei, C., Frese, K., et al. Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis. Nature 475 (2011), 106–109.
-
(2011)
Nature
, vol.475
, pp. 106-109
-
-
DeNicola, G.M.1
Karreth, F.A.2
Humpton, T.J.3
Gopinathan, A.4
Wei, C.5
Frese, K.6
-
58
-
-
51649130168
-
Cancer related mutations in NRF2 impair its recognition by Keap1-Cul3 E3 ligase and promote malignancy
-
[58] Shibata, T., Ohta, T., Tong, K.I., Kokubu, A., Odogawa, R., Tsuta, K., et al. Cancer related mutations in NRF2 impair its recognition by Keap1-Cul3 E3 ligase and promote malignancy. Proc Natl Acad Sci USA 105 (2008), 13568–13573.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 13568-13573
-
-
Shibata, T.1
Ohta, T.2
Tong, K.I.3
Kokubu, A.4
Odogawa, R.5
Tsuta, K.6
-
59
-
-
76649089973
-
Loss of Kelch-like ECH-associated protein 1 function in prostate cancer cells causes chemoresistance and radioresistance and promotes tumor growth
-
[59] Zhang, P., Singh, A., Yegnasubramanian, S., Esopi, D., Kombairaju, P., Bodas, M., et al. Loss of Kelch-like ECH-associated protein 1 function in prostate cancer cells causes chemoresistance and radioresistance and promotes tumor growth. Mol Cancer Ther 9 (2010), 336–346.
-
(2010)
Mol Cancer Ther
, vol.9
, pp. 336-346
-
-
Zhang, P.1
Singh, A.2
Yegnasubramanian, S.3
Esopi, D.4
Kombairaju, P.5
Bodas, M.6
-
60
-
-
80054772589
-
An antioxidant response phenotype shared between hereditary and sporadic type 2 papillary renal cell carcinoma
-
[60] Ooi, A., Wong, J.C., Petillo, D., Roossien, D., Perrier-Trudova, V., Whitten, D., et al. An antioxidant response phenotype shared between hereditary and sporadic type 2 papillary renal cell carcinoma. Cancer Cell 20 (2011), 511–523.
-
(2011)
Cancer Cell
, vol.20
, pp. 511-523
-
-
Ooi, A.1
Wong, J.C.2
Petillo, D.3
Roossien, D.4
Perrier-Trudova, V.5
Whitten, D.6
-
61
-
-
80054767730
-
Renal cyst formation in Fh1-deficient mice is independent of the Hif/Phd pathway: roles for fumarate in KEAP1 succination and Nrf2 signaling
-
[61] Adam, J., Hatipoglu, E., O'Flaherty, L., Ternette, N., Sahgal, N., Lockstone, H., et al. Renal cyst formation in Fh1-deficient mice is independent of the Hif/Phd pathway: roles for fumarate in KEAP1 succination and Nrf2 signaling. Cancer Cell 20 (2011), 524–537.
-
(2011)
Cancer Cell
, vol.20
, pp. 524-537
-
-
Adam, J.1
Hatipoglu, E.2
O'Flaherty, L.3
Ternette, N.4
Sahgal, N.5
Lockstone, H.6
-
62
-
-
84878785993
-
The Keap1-Nrf2 pathway: mechanisms of activation and dysregulation in cancer
-
[62] Kansanen, E., Kuosmanen, S.M., Leinonen, H., Levonen, A.L., The Keap1-Nrf2 pathway: mechanisms of activation and dysregulation in cancer. Redox Biol 1 (2013), 45–49.
-
(2013)
Redox Biol
, vol.1
, pp. 45-49
-
-
Kansanen, E.1
Kuosmanen, S.M.2
Leinonen, H.3
Levonen, A.L.4
-
63
-
-
84880048347
-
Nrf2 prevents initiation but accelerates progression through the Kras signaling pathway during lung carcinogenesis
-
[63] Satoh, H., Moriguchi, T., Takai, J., Ebina, M., Yamamoto, M., Nrf2 prevents initiation but accelerates progression through the Kras signaling pathway during lung carcinogenesis. Cancer Res 73 (2013), 4158–4168.
-
(2013)
Cancer Res
, vol.73
, pp. 4158-4168
-
-
Satoh, H.1
Moriguchi, T.2
Takai, J.3
Ebina, M.4
Yamamoto, M.5
-
64
-
-
0027485461
-
Bcl-2 functions in an antioxidant pathway to prevent apoptosis
-
[64] Hockenbery, D.M., Oltvai, Z.N., Yin, X.M., Milliman, C.L., Korsmeyer, S.J., Bcl-2 functions in an antioxidant pathway to prevent apoptosis. Cell 75 (1993), 241–251.
-
(1993)
Cell
, vol.75
, pp. 241-251
-
-
Hockenbery, D.M.1
Oltvai, Z.N.2
Yin, X.M.3
Milliman, C.L.4
Korsmeyer, S.J.5
-
65
-
-
3543072186
-
Overweight, obesity and cancer: epidemiological evidence and proposed mechanisms
-
[65] Calle, E.E., Kaaks, R., Overweight, obesity and cancer: epidemiological evidence and proposed mechanisms. Nat Rev Cancer 4 (2004), 579–591.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 579-591
-
-
Calle, E.E.1
Kaaks, R.2
-
66
-
-
0037464510
-
Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults
-
[66] Calle, E.E., Rodriguez, C., Walker-Thurmond, K., Thun, M.J., Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults. N Engl J Med 348 (2003), 1625–1638.
-
(2003)
N Engl J Med
, vol.348
, pp. 1625-1638
-
-
Calle, E.E.1
Rodriguez, C.2
Walker-Thurmond, K.3
Thun, M.J.4
-
67
-
-
85006768050
-
The metabolism of tumors in the body
-
[67] Warburg, O., Wind, F., Negelein, E., The metabolism of tumors in the body. J Gen Physiol 8 (1927), 519–530.
-
(1927)
J Gen Physiol
, vol.8
, pp. 519-530
-
-
Warburg, O.1
Wind, F.2
Negelein, E.3
-
68
-
-
0035021707
-
A tabulated summary of the FDG PET literature
-
[68] Gambhir, S.S., Czernin, J., Schwimmer, J., Silverman, D.H., Coleman, R.E., Phelps, M.E., A tabulated summary of the FDG PET literature. J Nucl Med 42 (2001), 1S–93S.
-
(2001)
J Nucl Med
, vol.42
, pp. 1S-93S
-
-
Gambhir, S.S.1
Czernin, J.2
Schwimmer, J.3
Silverman, D.H.4
Coleman, R.E.5
Phelps, M.E.6
-
69
-
-
0036717382
-
Molecular imaging of cancer with positron emission tomography
-
[69] Gambhir, S.S., Molecular imaging of cancer with positron emission tomography. Nat Rev Cancer 2 (2002), 683–693.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 683-693
-
-
Gambhir, S.S.1
-
70
-
-
34250712408
-
Tumor-specific positron emission tomography imaging in patients: [18F] fluorodeoxyglucose and beyond
-
[70] Mankoff, D.A., Eary, J.F., Link, J.M., Muzi, M., Rajendran, J.G., Spence, A.M., et al. Tumor-specific positron emission tomography imaging in patients: [18F] fluorodeoxyglucose and beyond. Clin Cancer Res 13 (2007), 3460–3469.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 3460-3469
-
-
Mankoff, D.A.1
Eary, J.F.2
Link, J.M.3
Muzi, M.4
Rajendran, J.G.5
Spence, A.M.6
-
71
-
-
84884893986
-
Brain tumor initiating cells adapt to restricted nutrition through preferential glucose uptake
-
[71] Flavahan, W.A., Wu, Q., Hitomi, M., Rahim, N., Kim, Y., Sloan, A.E., et al. Brain tumor initiating cells adapt to restricted nutrition through preferential glucose uptake. Nat Neurosci 16 (2013), 1373–1382.
-
(2013)
Nat Neurosci
, vol.16
, pp. 1373-1382
-
-
Flavahan, W.A.1
Wu, Q.2
Hitomi, M.3
Rahim, N.4
Kim, Y.5
Sloan, A.E.6
-
72
-
-
23044500915
-
Pyruvate kinase type M2 and its role in tumor growth and spreading
-
[72] Mazurek, S., Boschek, C.B., Hugo, F., Eigenbrodt, E., Pyruvate kinase type M2 and its role in tumor growth and spreading. Semin Cancer Biol 15 (2005), 300–308.
-
(2005)
Semin Cancer Biol
, vol.15
, pp. 300-308
-
-
Mazurek, S.1
Boschek, C.B.2
Hugo, F.3
Eigenbrodt, E.4
-
73
-
-
40749163248
-
The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth
-
[73] Christofk, H.R., Vander Heiden, M.G., Harris, M.H., Ramanathan, A., Gerszten, R.E., Wei, R., et al. The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth. Nature 452 (2008), 230–233.
-
(2008)
Nature
, vol.452
, pp. 230-233
-
-
Christofk, H.R.1
Vander Heiden, M.G.2
Harris, M.H.3
Ramanathan, A.4
Gerszten, R.E.5
Wei, R.6
-
74
-
-
79958103961
-
Pyruvate kinase type M2: a key regulator of the metabolic budget system in tumor cells
-
[74] Mazurek, S., Pyruvate kinase type M2: a key regulator of the metabolic budget system in tumor cells. Int J Biochem Cell Biol 43 (2011), 969–980.
-
(2011)
Int J Biochem Cell Biol
, vol.43
, pp. 969-980
-
-
Mazurek, S.1
-
75
-
-
84866842363
-
Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis
-
[75] Anastasiou, D., Yu, Y., Israelsen, W.J., Jiang, J.K., Boxer, M.B., Hong, B.S., et al. Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis. Nat Chem Biol 8 (2012), 839–847.
-
(2012)
Nat Chem Biol
, vol.8
, pp. 839-847
-
-
Anastasiou, D.1
Yu, Y.2
Israelsen, W.J.3
Jiang, J.K.4
Boxer, M.B.5
Hong, B.S.6
-
76
-
-
84905097406
-
Pyruvate kinase M2 and cancer: an updated assessment
-
[76] Iqbal, M.A., Gupta, V., Gopinath, P., Mazurek, S., Bamezai, R.N., Pyruvate kinase M2 and cancer: an updated assessment. FEBS Lett 588 (2014), 2685–2692.
-
(2014)
FEBS Lett
, vol.588
, pp. 2685-2692
-
-
Iqbal, M.A.1
Gupta, V.2
Gopinath, P.3
Mazurek, S.4
Bamezai, R.N.5
-
77
-
-
33344456073
-
Expression of transketolase TKTL1 predicts colon and urothelial cancer patient survival: Warburg effect reinterpreted
-
[77] Langbein, S., Zerilli, M., Zur Hausen, A., Staiger, W., Rensch-Boschert, K., Lukan, N., et al. Expression of transketolase TKTL1 predicts colon and urothelial cancer patient survival: Warburg effect reinterpreted. Br J Cancer 94 (2006), 578–585.
-
(2006)
Br J Cancer
, vol.94
, pp. 578-585
-
-
Langbein, S.1
Zerilli, M.2
Zur Hausen, A.3
Staiger, W.4
Rensch-Boschert, K.5
Lukan, N.6
-
78
-
-
34249942508
-
Transketolase protein TKTL1 overexpression: a potential biomarker and therapeutic target in breast cancer
-
[78] Földi, M., Stickeler, E., Bau, L., Kretz, O., Watermann, D., Gitsch, G., et al. Transketolase protein TKTL1 overexpression: a potential biomarker and therapeutic target in breast cancer. Oncol Rep 17 (2007), 841–845.
-
(2007)
Oncol Rep
, vol.17
, pp. 841-845
-
-
Földi, M.1
Stickeler, E.2
Bau, L.3
Kretz, O.4
Watermann, D.5
Gitsch, G.6
-
79
-
-
37449034854
-
Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis
-
[79] DeBerardinis, R.J., Mancuso, A., Daikhin, E., Nissim, I., Yudkoff, M., Wehrli, S., et al. Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis. Proc Natl Acad Sci USA 104 (2007), 19345–19350.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 19345-19350
-
-
DeBerardinis, R.J.1
Mancuso, A.2
Daikhin, E.3
Nissim, I.4
Yudkoff, M.5
Wehrli, S.6
-
80
-
-
70350217425
-
Glioblastoma cells require glutamate dehydrogenase to survive impairments of glucose metabolism or Akt signaling
-
[80] Yang, C., Sudderth, J., Dang, T., Bachoo, R.M., McDonald, J.G., DeBerardinis, R.J., Glioblastoma cells require glutamate dehydrogenase to survive impairments of glucose metabolism or Akt signaling. Cancer Res 69 (2009), 7986–7993.
-
(2009)
Cancer Res
, vol.69
, pp. 7986-7993
-
-
Yang, C.1
Sudderth, J.2
Dang, T.3
Bachoo, R.M.4
McDonald, J.G.5
DeBerardinis, R.J.6
-
81
-
-
84858120137
-
Targeting the lactate transporter MCT1 in endothelial cells inhibits lactate-induced HIF-1 activation and tumor angiogenesis
-
[81] Sonveaux, P., Copetti, T., De Saedeleer, C.J., Végran, F., Verrax, J., Kennedy, K.M., et al. Targeting the lactate transporter MCT1 in endothelial cells inhibits lactate-induced HIF-1 activation and tumor angiogenesis. PLoS One, 7, 2012, e33418.
-
(2012)
PLoS One
, vol.7
, pp. e33418
-
-
Sonveaux, P.1
Copetti, T.2
De Saedeleer, C.J.3
Végran, F.4
Verrax, J.5
Kennedy, K.M.6
-
82
-
-
0029908016
-
Expression of a constitutively active Akt Ser/Thr kinase in 3T3-L1 adipocytes stimulates glucose uptake and glucose transporter 4 translocation
-
[82] Kohn, A.D., Summers, S.A., Birnbaum, M.J., Roth, R.A., Expression of a constitutively active Akt Ser/Thr kinase in 3T3-L1 adipocytes stimulates glucose uptake and glucose transporter 4 translocation. J Biol Chem 271 (1996), 31372–31378.
-
(1996)
J Biol Chem
, vol.271
, pp. 31372-31378
-
-
Kohn, A.D.1
Summers, S.A.2
Birnbaum, M.J.3
Roth, R.A.4
-
83
-
-
0032571257
-
Insulin increases the association of Akt-2 with Glut4-containing vesicles
-
[83] Calera, M.R., Martinez, C., Liu, H., Jack, A.K., Birnbaum, M.J., Pilch, P.F., Insulin increases the association of Akt-2 with Glut4-containing vesicles. J Biol Chem 273 (1998), 7201–7204.
-
(1998)
J Biol Chem
, vol.273
, pp. 7201-7204
-
-
Calera, M.R.1
Martinez, C.2
Liu, H.3
Jack, A.K.4
Birnbaum, M.J.5
Pilch, P.F.6
-
84
-
-
0035853833
-
Akt and Bcl-xL promote growth factor-independent survival through distinct effects on mitochondrial physiology
-
[84] Plas, D.R., Talapatra, S., Edinger, A.L., Rathmell, J.C., Thompson, C.B., Akt and Bcl-xL promote growth factor-independent survival through distinct effects on mitochondrial physiology. J Biol Chem 276 (2001), 12041–12048.
-
(2001)
J Biol Chem
, vol.276
, pp. 12041-12048
-
-
Plas, D.R.1
Talapatra, S.2
Edinger, A.L.3
Rathmell, J.C.4
Thompson, C.B.5
-
85
-
-
0036320205
-
Akt maintains cell size and survival by increasing mTOR-dependent nutrient uptake
-
[85] Edinger, A.L., Thompson, C.B., Akt maintains cell size and survival by increasing mTOR-dependent nutrient uptake. Mol Biol Cell 13 (2002), 2276–2288.
-
(2002)
Mol Biol Cell
, vol.13
, pp. 2276-2288
-
-
Edinger, A.L.1
Thompson, C.B.2
-
86
-
-
0141863388
-
Akt-directed glucose metabolism can prevent Bax conformation change and promote growth factor-independent survival
-
[86] Rathmell, J.C., Fox, C.J., Plas, D.R., Hammerman, P.S., Cinalli, R.M., Thompson, C.B., Akt-directed glucose metabolism can prevent Bax conformation change and promote growth factor-independent survival. Mol Cell Biol 23 (2003), 7315–7328.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 7315-7328
-
-
Rathmell, J.C.1
Fox, C.J.2
Plas, D.R.3
Hammerman, P.S.4
Cinalli, R.M.5
Thompson, C.B.6
-
87
-
-
4544331713
-
Activation of PI3K is indispensable for interleukin 7-mediated viability, proliferation, glucose use, and growth of T cell acute lymphoblastic leukemia cells
-
[87] Barata, J.T., Silva, A., Brandao, J.G., Nadler, L.M., Cardoso, A.A., Boussiotis, V.A., Activation of PI3K is indispensable for interleukin 7-mediated viability, proliferation, glucose use, and growth of T cell acute lymphoblastic leukemia cells. J Exp Med 200 (2004), 659–669.
-
(2004)
J Exp Med
, vol.200
, pp. 659-669
-
-
Barata, J.T.1
Silva, A.2
Brandao, J.G.3
Nadler, L.M.4
Cardoso, A.A.5
Boussiotis, V.A.6
-
88
-
-
2542561169
-
Akt stimulates aerobic glycolysis in cancer cells
-
[88] Elstrom, R.L., Bauer, D.E., Buzzai, M., Karnauskas, R., Harris, M.H., Plas, D.R., et al. Akt stimulates aerobic glycolysis in cancer cells. Cancer Res 64 (2004), 3892–3899.
-
(2004)
Cancer Res
, vol.64
, pp. 3892-3899
-
-
Elstrom, R.L.1
Bauer, D.E.2
Buzzai, M.3
Karnauskas, R.4
Harris, M.H.5
Plas, D.R.6
-
89
-
-
37549032776
-
The interplay between MYC and HIF in cancer
-
[89] Dang, C.V., Kim, J.W., Gao, P., Yustein, J., The interplay between MYC and HIF in cancer. Nat Rev Cancer 8 (2008), 51–56.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 51-56
-
-
Dang, C.V.1
Kim, J.W.2
Gao, P.3
Yustein, J.4
-
90
-
-
57749088701
-
Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction
-
[90] Wise, D.R., DeBerardinis, R.J., Mancuso, A., Sayed, N., Zhang, X.Y., Pfeiffer, H.K., et al. Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction. Proc Natl Acad Sci USA 105 (2008), 18782–18787.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 18782-18787
-
-
Wise, D.R.1
DeBerardinis, R.J.2
Mancuso, A.3
Sayed, N.4
Zhang, X.Y.5
Pfeiffer, H.K.6
-
91
-
-
75149148563
-
Q's next: the diverse functions of glutamine in metabolism, cell biology and cancer
-
[91] DeBerardinis, R.J., Cheng, T., Q's next: the diverse functions of glutamine in metabolism, cell biology and cancer. Oncogene 29 (2010), 313–324.
-
(2010)
Oncogene
, vol.29
, pp. 313-324
-
-
DeBerardinis, R.J.1
Cheng, T.2
-
92
-
-
84893852306
-
Metabolic changes in cancer cells upon suppression of MYC
-
[92] Anso, E., Mullen, A.R., Felsher, D.W., Matés, J.M., Deberardinis, R.J., Chandel, N.S., Metabolic changes in cancer cells upon suppression of MYC. Cancer Metab, 1, 2013, 7.
-
(2013)
Cancer Metab
, vol.1
, pp. 7
-
-
Anso, E.1
Mullen, A.R.2
Felsher, D.W.3
Matés, J.M.4
Deberardinis, R.J.5
Chandel, N.S.6
-
93
-
-
0030882879
-
Glucose catabolism in cancer cells. The type II hexokinase promoter contains functionally active response elements for the tumor suppressor p53
-
[93] Mathupala, S.P., Heese, C., Pedersen, P.L., Glucose catabolism in cancer cells. The type II hexokinase promoter contains functionally active response elements for the tumor suppressor p53. J Biol Chem 272 (1997), 22776–22780.
-
(1997)
J Biol Chem
, vol.272
, pp. 22776-22780
-
-
Mathupala, S.P.1
Heese, C.2
Pedersen, P.L.3
-
94
-
-
0033257077
-
Identification of seven genes regulated by wild-type p53 in a colon cancer cell line carrying a well-controlled wild-type p53 expression system
-
[94] Okamura, S., Ng, C.C., Koyama, K., Takei, Y., Arakawa, H., Monden, M., et al. Identification of seven genes regulated by wild-type p53 in a colon cancer cell line carrying a well-controlled wild-type p53 expression system. Oncol Res 11 (1999), 281–285.
-
(1999)
Oncol Res
, vol.11
, pp. 281-285
-
-
Okamura, S.1
Ng, C.C.2
Koyama, K.3
Takei, Y.4
Arakawa, H.5
Monden, M.6
-
95
-
-
1942506067
-
The tumor suppressor p53 down-regulates glucose transporters GLUT1 and GLUT4 gene expression
-
[95] Schwartzenberg-Bar-Yoseph, F., Armoni, M., Karnieli, E., The tumor suppressor p53 down-regulates glucose transporters GLUT1 and GLUT4 gene expression. Cancer Res 64 (2004), 2627–2633.
-
(2004)
Cancer Res
, vol.64
, pp. 2627-2633
-
-
Schwartzenberg-Bar-Yoseph, F.1
Armoni, M.2
Karnieli, E.3
-
96
-
-
33745149291
-
p53 regulates mitochondrial respiration
-
[96] Matoba, S., Kang, J.G., Patino, W.D., Wragg, A., Boehm, M., Gavrilova, O., et al. p53 regulates mitochondrial respiration. Science 312 (2006), 1650–1653.
-
(2006)
Science
, vol.312
, pp. 1650-1653
-
-
Matoba, S.1
Kang, J.G.2
Patino, W.D.3
Wragg, A.4
Boehm, M.5
Gavrilova, O.6
-
97
-
-
33745918951
-
TIGAR, a p53-inducible regulator of glycolysis and apoptosis
-
[97] Bensaad, K., Tsuruta, A., Selak, M.A., Vidal, M.N., Nakano, K., Bartrons, R., et al. TIGAR, a p53-inducible regulator of glycolysis and apoptosis. Cell 126 (2006), 107–120.
-
(2006)
Cell
, vol.126
, pp. 107-120
-
-
Bensaad, K.1
Tsuruta, A.2
Selak, M.A.3
Vidal, M.N.4
Nakano, K.5
Bartrons, R.6
-
98
-
-
84869077946
-
Phosphoglycerate mutase 1 coordinates glycolysis and biosynthesis to promote tumor growth
-
[98] Hitosugi, T., Zhou, L., Elf, S., Fan, J., Kang, H.B., Seo, J.H., et al. Phosphoglycerate mutase 1 coordinates glycolysis and biosynthesis to promote tumor growth. Cancer Cell 22 (2012), 585–600.
-
(2012)
Cancer Cell
, vol.22
, pp. 585-600
-
-
Hitosugi, T.1
Zhou, L.2
Elf, S.3
Fan, J.4
Kang, H.B.5
Seo, J.H.6
-
99
-
-
52949127312
-
An integrated genomic analysis of human glioblastoma multiforme
-
[99] Parsons, D.W., Jones, S., Zhang, X., Lin, J.C., Leary, R.J., Angenendt, P., et al. An integrated genomic analysis of human glioblastoma multiforme. Science 321 (2008), 1807–1812.
-
(2008)
Science
, vol.321
, pp. 1807-1812
-
-
Parsons, D.W.1
Jones, S.2
Zhang, X.3
Lin, J.C.4
Leary, R.J.5
Angenendt, P.6
-
100
-
-
73649088347
-
Mutant metabolic enzymes are at the origin of gliomas
-
[100] Yan, H., Bigner, D.D., Velculescu, V., Parsons, D.W., Mutant metabolic enzymes are at the origin of gliomas. Cancer Res 69 (2009), 9157–9159.
-
(2009)
Cancer Res
, vol.69
, pp. 9157-9159
-
-
Yan, H.1
Bigner, D.D.2
Velculescu, V.3
Parsons, D.W.4
-
101
-
-
60849115270
-
IDH1 and IDH2 mutations in gliomas
-
[101] Yan, H., Parsons, D.W., Jin, G., McLendon, R., Rasheed, B.A., Yuan, W., et al. IDH1 and IDH2 mutations in gliomas. N Engl J Med 360 (2009), 765–773.
-
(2009)
N Engl J Med
, vol.360
, pp. 765-773
-
-
Yan, H.1
Parsons, D.W.2
Jin, G.3
McLendon, R.4
Rasheed, B.A.5
Yuan, W.6
-
102
-
-
70149093912
-
Recurring mutations found by sequencing an acute myeloid leukemia genome
-
[102] Mardis, E.R., Ding, L., Dooling, D.J., Larson, D.E., McLellan, M.D., Chen, K., et al. Recurring mutations found by sequencing an acute myeloid leukemia genome. N Engl J Med 361 (2009), 1058–1066.
-
(2009)
N Engl J Med
, vol.361
, pp. 1058-1066
-
-
Mardis, E.R.1
Ding, L.2
Dooling, D.J.3
Larson, D.E.4
McLellan, M.D.5
Chen, K.6
-
103
-
-
72049125350
-
Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
-
[103] Dang, L., White, D.W., Gross, S., Bennett, B.D., Bittinger, M.A., Driggers, E.M., et al. Cancer-associated IDH1 mutations produce 2-hydroxyglutarate. Nature 462 (2009), 739–744.
-
(2009)
Nature
, vol.462
, pp. 739-744
-
-
Dang, L.1
White, D.W.2
Gross, S.3
Bennett, B.D.4
Bittinger, M.A.5
Driggers, E.M.6
-
104
-
-
64849098267
-
Glioma-derived mutations in IDH1 dominantly inhibit IDH1 catalytic activity and induce HIF-1alpha
-
[104] Zhao, S., Lin, Y., Xu, W., Jiang, W., Zha, Z., Wang, P., et al. Glioma-derived mutations in IDH1 dominantly inhibit IDH1 catalytic activity and induce HIF-1alpha. Science 324 (2009), 261–265.
-
(2009)
Science
, vol.324
, pp. 261-265
-
-
Zhao, S.1
Lin, Y.2
Xu, W.3
Jiang, W.4
Zha, Z.5
Wang, P.6
-
105
-
-
26444570010
-
Accumulation of Krebs cycle intermediates and over-expression of HIF1alpha in tumours which result from germline FH and SDH mutations
-
[105] Pollard, P.J., Brière, J.J., Alam, N.A., Barwell, J., Barclay, E., Wortham, N.C., et al. Accumulation of Krebs cycle intermediates and over-expression of HIF1alpha in tumours which result from germline FH and SDH mutations. Hum Mol Genet 14 (2005), 2231–2239.
-
(2005)
Hum Mol Genet
, vol.14
, pp. 2231-2239
-
-
Pollard, P.J.1
Brière, J.J.2
Alam, N.A.3
Barwell, J.4
Barclay, E.5
Wortham, N.C.6
-
106
-
-
19944433653
-
Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase
-
[106] Selak, M.A., Armour, S.M., MacKenzie, E.D., Boulahbel, H., Watson, D.G., Mansfield, K.D., et al. Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase. Cancer Cell 7 (2005), 77–85.
-
(2005)
Cancer Cell
, vol.7
, pp. 77-85
-
-
Selak, M.A.1
Armour, S.M.2
MacKenzie, E.D.3
Boulahbel, H.4
Watson, D.G.5
Mansfield, K.D.6
-
107
-
-
80052744948
-
SDH mutations in cancer
-
[107] Bardella, C., Pollard, P.J., Tomlinson, I., SDH mutations in cancer. Biochim Biophys Acta 1807 (2011), 1432–1443.
-
(2011)
Biochim Biophys Acta
, vol.1807
, pp. 1432-1443
-
-
Bardella, C.1
Pollard, P.J.2
Tomlinson, I.3
-
108
-
-
84921501276
-
Teaching the basics of autophagy and mitophagy to redox biologists – mechanisms and experimental approaches
-
[108] Zhang, J., Teaching the basics of autophagy and mitophagy to redox biologists – mechanisms and experimental approaches. Redox Biol 4 (2015), 242–259.
-
(2015)
Redox Biol
, vol.4
, pp. 242-259
-
-
Zhang, J.1
-
109
-
-
84884820821
-
Autophagy regulation and its role in cancer
-
[109] Lorin, S., Hamaï, A., Mehrpour, M., Codogno, P., Autophagy regulation and its role in cancer. Semin Cancer Biol 23 (2013), 361–379.
-
(2013)
Semin Cancer Biol
, vol.23
, pp. 361-379
-
-
Lorin, S.1
Hamaï, A.2
Mehrpour, M.3
Codogno, P.4
-
110
-
-
11244297916
-
Dysregulation of the TSC-mTOR pathway in human disease
-
[110] Inoki, K., Corradetti, M.N., Guan, K.L., Dysregulation of the TSC-mTOR pathway in human disease. Nat Genet 37 (2005), 19–24.
-
(2005)
Nat Genet
, vol.37
, pp. 19-24
-
-
Inoki, K.1
Corradetti, M.N.2
Guan, K.L.3
-
111
-
-
0000906170
-
Induction of autophagy and inhibition of tumorigenesis by beclin 1
-
[111] Liang, X.H., Jackson, S., Seaman, M., Brown, K., Kempkes, B., Hibshoosh, H., et al. Induction of autophagy and inhibition of tumorigenesis by beclin 1. Nature 402 (1999), 672–676.
-
(1999)
Nature
, vol.402
, pp. 672-676
-
-
Liang, X.H.1
Jackson, S.2
Seaman, M.3
Brown, K.4
Kempkes, B.5
Hibshoosh, H.6
-
112
-
-
9144240441
-
Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene
-
[112] Qu, X., Yu, J., Bhagat, G., Furuya, N., Hibshoosh, H., Troxel, A., et al. Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene. J Clin Invest 112 (2003), 1809–1820.
-
(2003)
J Clin Invest
, vol.112
, pp. 1809-1820
-
-
Qu, X.1
Yu, J.2
Bhagat, G.3
Furuya, N.4
Hibshoosh, H.5
Troxel, A.6
-
113
-
-
0345166111
-
Beclin 1, an autophagy gene essential for early embryonic development, is a haploin sufficient tumor suppressor
-
[113] Yue, Z., Jin, S., Yang, C., Levine, A.J., Heintz, N., Beclin 1, an autophagy gene essential for early embryonic development, is a haploin sufficient tumor suppressor. Proc Natl Acad Sci USA 100 (2003), 15077–15082.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 15077-15082
-
-
Yue, Z.1
Jin, S.2
Yang, C.3
Levine, A.J.4
Heintz, N.5
-
114
-
-
34547132328
-
Tissue-specific autophagy alterations and increased tumorigenesis in mice deficient in Atg4C/autophagin-3
-
[114] Mariño, G., Salvador-Montoliu, N., Fueyo, A., Knecht, E., Mizushima, N., López-Otín, C., Tissue-specific autophagy alterations and increased tumorigenesis in mice deficient in Atg4C/autophagin-3. J Biol Chem 282 (2007), 18573–18583.
-
(2007)
J Biol Chem
, vol.282
, pp. 18573-18583
-
-
Mariño, G.1
Salvador-Montoliu, N.2
Fueyo, A.3
Knecht, E.4
Mizushima, N.5
López-Otín, C.6
-
115
-
-
79955377420
-
Autophagy-deficient mice develop multiple liver tumors
-
[115] Takamura, A., Komatsu, M., Hara, T., Sakamoto, A., Kishi, C., Waguri, S., et al. Autophagy-deficient mice develop multiple liver tumors. Genes Dev 25 (2011), 795–800.
-
(2011)
Genes Dev
, vol.25
, pp. 795-800
-
-
Takamura, A.1
Komatsu, M.2
Hara, T.3
Sakamoto, A.4
Kishi, C.5
Waguri, S.6
-
116
-
-
77949541314
-
High expression of gabarapl1 is associated with a better outcome for patients with lymph node-positive breast cancer
-
[116] Berthier, A., Seguin, S., Sasco, A.J., Bobin, J.Y., De Laroche, G., Datchary, J., et al. High expression of gabarapl1 is associated with a better outcome for patients with lymph node-positive breast cancer. Br J Cancer 102 (2010), 1024–1031.
-
(2010)
Br J Cancer
, vol.102
, pp. 1024-1031
-
-
Berthier, A.1
Seguin, S.2
Sasco, A.J.3
Bobin, J.Y.4
De Laroche, G.5
Datchary, J.6
-
117
-
-
84898605742
-
Low expression of GABARAPL1 is associated with a poor outcome for patients with hepatocellular carcinoma
-
[117] Liu, C., Xia, Y., Jiang, W., Liu, Y., Yu, L., Low expression of GABARAPL1 is associated with a poor outcome for patients with hepatocellular carcinoma. Oncol Rep 31 (2014), 2043–2048.
-
(2014)
Oncol Rep
, vol.31
, pp. 2043-2048
-
-
Liu, C.1
Xia, Y.2
Jiang, W.3
Liu, Y.4
Yu, L.5
-
118
-
-
77955172368
-
Autophagy negatively regulates Wnt signalling by promoting Dishevelled degradation
-
[118] Gao, C., Cao, W., Bao, L., Zuo, W., Xie, G., Cai, T., et al. Autophagy negatively regulates Wnt signalling by promoting Dishevelled degradation. Nat Cell Biol 12 (2010), 781–790.
-
(2010)
Nat Cell Biol
, vol.12
, pp. 781-790
-
-
Gao, C.1
Cao, W.2
Bao, L.3
Zuo, W.4
Xie, G.5
Cai, T.6
-
119
-
-
79959467280
-
GABARAPL1 negatively regulates Wnt/ß-catenin signaling by mediating Dvl2 degradation through the autophagy pathway
-
[119] Zhang, Y., Wang, F., Han, L., Wu, Y., Li, S., Yang, X., et al. GABARAPL1 negatively regulates Wnt/ß-catenin signaling by mediating Dvl2 degradation through the autophagy pathway. Cell Physiol Biochem 27 (2011), 503–512.
-
(2011)
Cell Physiol Biochem
, vol.27
, pp. 503-512
-
-
Zhang, Y.1
Wang, F.2
Han, L.3
Wu, Y.4
Li, S.5
Yang, X.6
-
120
-
-
84903601805
-
The role of GABARAPL1/GEC1 in autophagic flux and mitochondrial quality control in MDA-MB-436 breast cancer cells
-
[120] Boyer-Guittaut, M., Poillet, L., Liang, Q., Bôle-Richard, E., Ouyang, X., Benavides, G.A., et al. The role of GABARAPL1/GEC1 in autophagic flux and mitochondrial quality control in MDA-MB-436 breast cancer cells. Autophagy 10 (2014), 986–1003.
-
(2014)
Autophagy
, vol.10
, pp. 986-1003
-
-
Boyer-Guittaut, M.1
Poillet, L.2
Liang, Q.3
Bôle-Richard, E.4
Ouyang, X.5
Benavides, G.A.6
-
121
-
-
84876861153
-
Paracrine Wnt signaling both promotes and inhibits human breast tumor growth
-
[121] Green, J.L., La, J., Yum, K.W., Desai, P., Rodewald, L.W., Zhang, X., et al. Paracrine Wnt signaling both promotes and inhibits human breast tumor growth. Proc Natl Acad Sci USA 110 (2013), 6991–6996.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 6991-6996
-
-
Green, J.L.1
La, J.2
Yum, K.W.3
Desai, P.4
Rodewald, L.W.5
Zhang, X.6
-
122
-
-
84897482887
-
Tumour cell heterogeneity maintained by cooperating subclones in Wnt-driven mammary cancers
-
[122] Cleary, A.S., Leonard, T.L., Gestl, S.A., Gunther, E.J., Tumour cell heterogeneity maintained by cooperating subclones in Wnt-driven mammary cancers. Nature 508 (2014), 113–117.
-
(2014)
Nature
, vol.508
, pp. 113-117
-
-
Cleary, A.S.1
Leonard, T.L.2
Gestl, S.A.3
Gunther, E.J.4
-
123
-
-
79960401862
-
Suppression of autophagy by FIP200 deletion inhibits mammary tumorigenesis
-
[123] Wei, H., Wei, S., Gan, B., Peng, X., Zou, W., Guan, J.L., Suppression of autophagy by FIP200 deletion inhibits mammary tumorigenesis. Genes Dev 25 (2011), 1510–1527.
-
(2011)
Genes Dev
, vol.25
, pp. 1510-1527
-
-
Wei, H.1
Wei, S.2
Gan, B.3
Peng, X.4
Zou, W.5
Guan, J.L.6
-
124
-
-
84890018924
-
Autophagy-mediated tumor promotion
-
[124] Guo, J.Y., Xia, B., White, E., Autophagy-mediated tumor promotion. Cell 155 (2013), 1216–1219.
-
(2013)
Cell
, vol.155
, pp. 1216-1219
-
-
Guo, J.Y.1
Xia, B.2
White, E.3
-
125
-
-
80052227050
-
Autophagy as a target for anticancer therapy
-
[125] Janku, F., McConkey, D.J., Hong, D.S., Kurzrock, R., Autophagy as a target for anticancer therapy. Nat Rev Clin Oncol 8 (2011), 528–539.
-
(2011)
Nat Rev Clin Oncol
, vol.8
, pp. 528-539
-
-
Janku, F.1
McConkey, D.J.2
Hong, D.S.3
Kurzrock, R.4
-
126
-
-
78751556979
-
Autophagy as a therapeutic target in cancer
-
[126] Chen, N., Karantza, V., Autophagy as a therapeutic target in cancer. Cancer Biol Ther 11 (2011), 157–168.
-
(2011)
Cancer Biol Ther
, vol.11
, pp. 157-168
-
-
Chen, N.1
Karantza, V.2
-
127
-
-
0344441899
-
Alterations in the common fragile site gene Parkin in ovarian and other cancers
-
[127] Denison, S.R., Wang, F., Becker, N.A., Schüle, B., Kock, N., Phillips, L.A., et al. Alterations in the common fragile site gene Parkin in ovarian and other cancers. Oncogene 22 (2003), 8370–8378.
-
(2003)
Oncogene
, vol.22
, pp. 8370-8378
-
-
Denison, S.R.1
Wang, F.2
Becker, N.A.3
Schüle, B.4
Kock, N.5
Phillips, L.A.6
-
128
-
-
0038732456
-
Parkin, a gene implicated in autosomal recessive juvenile parkinsonism, is a candidate tumor suppressor gene on chromosome 6q25-q27
-
[128] Cesari, R., Martin, E.S., Calin, G.A., Pentimalli, F., Bichi, R., McAdams, H., et al. Parkin, a gene implicated in autosomal recessive juvenile parkinsonism, is a candidate tumor suppressor gene on chromosome 6q25-q27. Proc Natl Acad Sci USA 100 (2003), 5956–5961.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 5956-5961
-
-
Cesari, R.1
Martin, E.S.2
Calin, G.A.3
Pentimalli, F.4
Bichi, R.5
McAdams, H.6
-
129
-
-
11144355981
-
Alterations of the tumor suppressor gene Parkin in non-small cell lung cancer
-
[129] Picchio, M.C., Martin, E.S., Cesari, R., Calin, G.A., Yendamuri, S., Kuroki, T., et al. Alterations of the tumor suppressor gene Parkin in non-small cell lung cancer. Clin Cancer Res 10 (2004), 2720–2724.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 2720-2724
-
-
Picchio, M.C.1
Martin, E.S.2
Cesari, R.3
Calin, G.A.4
Yendamuri, S.5
Kuroki, T.6
-
130
-
-
2342468174
-
Parkin gene alterations in hepatocellular carcinoma
-
[130] Wang, F., Denison, S., Lai, J.P., Philips, L.A., Montoya, D., Kock, N., et al. Parkin gene alterations in hepatocellular carcinoma. Genes Chromosom Cancer 40 (2004), 85–96.
-
(2004)
Genes Chromosom Cancer
, vol.40
, pp. 85-96
-
-
Wang, F.1
Denison, S.2
Lai, J.P.3
Philips, L.A.4
Montoya, D.5
Kock, N.6
-
131
-
-
53649108020
-
Parkin as a tumor suppressor gene for hepatocellular carcinoma
-
[131] Fujiwara, M., Marusawa, H., Wang, H.Q., Iwai, A., Ikeuchi, K., Imai, Y., et al. Parkin as a tumor suppressor gene for hepatocellular carcinoma. Oncogene 27 (2008), 6002–6011.
-
(2008)
Oncogene
, vol.27
, pp. 6002-6011
-
-
Fujiwara, M.1
Marusawa, H.2
Wang, H.Q.3
Iwai, A.4
Ikeuchi, K.5
Imai, Y.6
-
132
-
-
73349125417
-
Somatic mutations of the Parkinson's disease-associated gene PARK2 in glioblastoma and other human malignancies
-
[132] Veeriah, S., Taylor, B.S., Meng, S., Fang, F., Yilmaz, E., Vivanco, I., et al. Somatic mutations of the Parkinson's disease-associated gene PARK2 in glioblastoma and other human malignancies. Nat Genet 42 (2010), 77–82.
-
(2010)
Nat Genet
, vol.42
, pp. 77-82
-
-
Veeriah, S.1
Taylor, B.S.2
Meng, S.3
Fang, F.4
Yilmaz, E.5
Vivanco, I.6
-
133
-
-
84861111156
-
Parkin pathway activation mitigates glioma cell proliferation and predicts patient survival
-
[133] Yeo, C.W., Ng, F.S., Chai, C., Tan, J.M., Koh, G.R., Chong, Y.K., et al. Parkin pathway activation mitigates glioma cell proliferation and predicts patient survival. Cancer Res 72 (2012), 2543–2553.
-
(2012)
Cancer Res
, vol.72
, pp. 2543-2553
-
-
Yeo, C.W.1
Ng, F.S.2
Chai, C.3
Tan, J.M.4
Koh, G.R.5
Chong, Y.K.6
-
134
-
-
84875909195
-
Parkin deficiency contributes to pancreatic tumorigenesis by inducing spindle multipolarity and misorientation
-
[134] Sun, X., Liu, M., Hao, J., Li, D., Luo, Y., Wang, X., et al. Parkin deficiency contributes to pancreatic tumorigenesis by inducing spindle multipolarity and misorientation. Cell Cycle 12 (2013), 1133–1141.
-
(2013)
Cell Cycle
, vol.12
, pp. 1133-1141
-
-
Sun, X.1
Liu, M.2
Hao, J.3
Li, D.4
Luo, Y.5
Wang, X.6
-
135
-
-
84861204926
-
PINK1- and Parkin-mediated mitophagy at a glance
-
[135] Jin, S.M., Youle, R.J., PINK1- and Parkin-mediated mitophagy at a glance. J Cell Sci 125 (2012), 795–799.
-
(2012)
J Cell Sci
, vol.125
, pp. 795-799
-
-
Jin, S.M.1
Youle, R.J.2
-
136
-
-
84863430453
-
Mitophagy: a complex mechanism of mitochondrial removal
-
[136] Novak, I., Mitophagy: a complex mechanism of mitochondrial removal. Antioxid Redox Signal 17 (2012), 794–802.
-
(2012)
Antioxid Redox Signal
, vol.17
, pp. 794-802
-
-
Novak, I.1
-
137
-
-
84867773087
-
Mitophagy: mechanisms, pathophysiological roles, and analysis
-
[137] Ding, W.X., Yin, X.M., Mitophagy: mechanisms, pathophysiological roles, and analysis. Biol Chem 393 (2012), 547–564.
-
(2012)
Biol Chem
, vol.393
, pp. 547-564
-
-
Ding, W.X.1
Yin, X.M.2
-
138
-
-
84876296881
-
Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization
-
[138] Sarraf, S.A., Raman, M., Guarani-Pereira, V., Sowa, M.E., Huttlin, E.L., Gygi, S.P., et al. Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization. Nature 496 (2013), 372–376.
-
(2013)
Nature
, vol.496
, pp. 372-376
-
-
Sarraf, S.A.1
Raman, M.2
Guarani-Pereira, V.3
Sowa, M.E.4
Huttlin, E.L.5
Gygi, S.P.6
-
139
-
-
84876531457
-
2nd. PINK1-phosphorylated mitofusin 2 is a Parkin receptor for culling damaged mitochondria
-
[139] Chen, Y., Dorn, G.W., 2nd. PINK1-phosphorylated mitofusin 2 is a Parkin receptor for culling damaged mitochondria. Science 340 (2013), 471–475.
-
(2013)
Science
, vol.340
, pp. 471-475
-
-
Chen, Y.1
Dorn, G.W.2
-
140
-
-
81055140895
-
PINK1 and Parkin target Miro for phosphorylation and degradation to arrest mitochondrial motility
-
[140] Wang, X., Winter, D., Ashrafi, G., Schlehe, J., Wong, Y.L., Selkoe, D., et al. PINK1 and Parkin target Miro for phosphorylation and degradation to arrest mitochondrial motility. Cell 147 (2011), 893–906.
-
(2011)
Cell
, vol.147
, pp. 893-906
-
-
Wang, X.1
Winter, D.2
Ashrafi, G.3
Schlehe, J.4
Wong, Y.L.5
Selkoe, D.6
-
141
-
-
84938080852
-
Mitofusin-2 over-expresses and leads to dysregulation of cell cycle and cell invasion in lung adenocarcinoma
-
[141] Lou, Y., Li, R., Liu, J., Zhang, Y., Zhang, X., Jin, B., et al. Mitofusin-2 over-expresses and leads to dysregulation of cell cycle and cell invasion in lung adenocarcinoma. Med Oncol, 32, 2015, 132.
-
(2015)
Med Oncol
, vol.32
, pp. 132
-
-
Lou, Y.1
Li, R.2
Liu, J.3
Zhang, Y.4
Zhang, X.5
Jin, B.6
-
142
-
-
84655165023
-
Anti-tumour efficacy of mitofusin-2 in urinary bladder carcinoma
-
[142] Jin, B., Fu, G., Pan, H., Cheng, X., Zhou, L., Lv, J., et al. Anti-tumour efficacy of mitofusin-2 in urinary bladder carcinoma. Med Oncol 28 (2011), S373–S380.
-
(2011)
Med Oncol
, vol.28
, pp. S373-S380
-
-
Jin, B.1
Fu, G.2
Pan, H.3
Cheng, X.4
Zhou, L.5
Lv, J.6
-
143
-
-
84891639275
-
Anti-tumor effects of Mfn2 in gastric cancer
-
[143] Zhang, G.E., Jin, H.L., Lin, X.K., Chen, C., Liu, X.S., Zhang, Q., et al. Anti-tumor effects of Mfn2 in gastric cancer. Int J Mol Sci 14 (2013), 13005–13021.
-
(2013)
Int J Mol Sci
, vol.14
, pp. 13005-13021
-
-
Zhang, G.E.1
Jin, H.L.2
Lin, X.K.3
Chen, C.4
Liu, X.S.5
Zhang, Q.6
-
144
-
-
84860914473
-
Inhibition of mitochondrial fission prevents cell cycle progression in lung cancer
-
[144] Rehman, J., Zhang, H.J., Toth, P.T., Zhang, Y., Marsboom, G., Hong, Z., et al. Inhibition of mitochondrial fission prevents cell cycle progression in lung cancer. FASEB J 26 (2012), 2175–2186.
-
(2012)
FASEB J
, vol.26
, pp. 2175-2186
-
-
Rehman, J.1
Zhang, H.J.2
Toth, P.T.3
Zhang, Y.4
Marsboom, G.5
Hong, Z.6
-
145
-
-
80355127945
-
Gustafsson ÅB. Mitochondrial autophagy by Bnip3 involves Drp1-mediated mitochondrial fission and recruitment of Parkin in cardiac myocytes
-
[145] Lee, Y., Lee, H.Y., Hanna, R.A., Gustafsson ÅB. Mitochondrial autophagy by Bnip3 involves Drp1-mediated mitochondrial fission and recruitment of Parkin in cardiac myocytes. Am J Physiol Heart Circ Physiol 301 (2011), H1924–H1931.
-
(2011)
Am J Physiol Heart Circ Physiol
, vol.301
, pp. H1924-H1931
-
-
Lee, Y.1
Lee, H.Y.2
Hanna, R.A.3
-
146
-
-
84938690751
-
Autophagy capacity and sub-mitochondrial heterogeneity shape Bnip3-induced mitophagy regulation of apoptosis
-
[146] Choe, S.C., Hamacher-Brady, A., Brady, N.R., Autophagy capacity and sub-mitochondrial heterogeneity shape Bnip3-induced mitophagy regulation of apoptosis. Cell Commun Signal, 13, 2015, 37.
-
(2015)
Cell Commun Signal
, vol.13
, pp. 37
-
-
Choe, S.C.1
Hamacher-Brady, A.2
Brady, N.R.3
-
147
-
-
84940796811
-
Mitophagy defects arising from BNip3 loss promote mammary tumor progression to metastasis
-
[147] Chourasia, A.H., Tracy, K., Frankenberger, C., Boland, M.L., Sharifi, M.N., Drake, L.E., et al. Mitophagy defects arising from BNip3 loss promote mammary tumor progression to metastasis. EMBO Rep 16 (2015), 1145–1163.
-
(2015)
EMBO Rep
, vol.16
, pp. 1145-1163
-
-
Chourasia, A.H.1
Tracy, K.2
Frankenberger, C.3
Boland, M.L.4
Sharifi, M.N.5
Drake, L.E.6
-
148
-
-
0034255036
-
Expression of the gene encoding the proapoptotic Nip3 protein is induced by hypoxia
-
[148] Bruick, R.K., Expression of the gene encoding the proapoptotic Nip3 protein is induced by hypoxia. Proc Natl Acad Sci USA 97 (2000), 9082–9087.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 9082-9087
-
-
Bruick, R.K.1
-
149
-
-
84940180529
-
The emerging theme of redox bioenergetics in health and disease
-
[149] Kramer, P.A., Darley-Usmar, V.M., The emerging theme of redox bioenergetics in health and disease. Biomed J 38 (2015), 294–300.
-
(2015)
Biomed J
, vol.38
, pp. 294-300
-
-
Kramer, P.A.1
Darley-Usmar, V.M.2
-
150
-
-
84902462980
-
Cell culture, oxidative stress, and antioxidants: avoiding pitfalls
-
[150] Halliwell, B., Cell culture, oxidative stress, and antioxidants: avoiding pitfalls. Biomed J 37 (2014), 99–105.
-
(2014)
Biomed J
, vol.37
, pp. 99-105
-
-
Halliwell, B.1
-
151
-
-
84902463475
-
Anti-cancer activities of omega -6 polyunsaturated fatty acids
-
[151] Xu, Y., Qian, S.Y., Anti-cancer activities of omega -6 polyunsaturated fatty acids. Biomed J 37 (2014), 112–119.
-
(2014)
Biomed J
, vol.37
, pp. 112-119
-
-
Xu, Y.1
Qian, S.Y.2
-
152
-
-
32444433202
-
Free radicals, metals and antioxidants in oxidative stress-induced cancer
-
[152] Valko, M., Rhodes, C.J., Moncol, J., Izakovic, M., Mazur, M., Free radicals, metals and antioxidants in oxidative stress-induced cancer. Chem Biol Interact 160 (2006), 1–40.
-
(2006)
Chem Biol Interact
, vol.160
, pp. 1-40
-
-
Valko, M.1
Rhodes, C.J.2
Moncol, J.3
Izakovic, M.4
Mazur, M.5
-
153
-
-
79251517382
-
Regulation of cancer cell metabolism
-
[153] Cairns, R.A., Harris, I.S., Mak, T.W., Regulation of cancer cell metabolism. Nat Rev Cancer 11 (2011), 85–95.
-
(2011)
Nat Rev Cancer
, vol.11
, pp. 85-95
-
-
Cairns, R.A.1
Harris, I.S.2
Mak, T.W.3
-
154
-
-
33746466098
-
Mitochondrial mutations in cancer
-
[154] Brandon, M., Baldi, P., Wallace, D.C., Mitochondrial mutations in cancer. Oncogene 25 (2006), 4647–4662.
-
(2006)
Oncogene
, vol.25
, pp. 4647-4662
-
-
Brandon, M.1
Baldi, P.2
Wallace, D.C.3
-
155
-
-
58249093939
-
How mitochondria produce reactive oxygen species
-
[155] Murphy, M.P., How mitochondria produce reactive oxygen species. Biochem J 417 (2009), 1–13.
-
(2009)
Biochem J
, vol.417
, pp. 1-13
-
-
Murphy, M.P.1
-
156
-
-
84920971375
-
Interplay between ROS and autophagy in cancer cells, from tumor initiation to cancer therapy
-
[156] Poillet-Perez, L., Despouy, G., Delage-Mourroux, R., Boyer-Guittaut, M., Interplay between ROS and autophagy in cancer cells, from tumor initiation to cancer therapy. Redox Biol 4 (2015), 184–192.
-
(2015)
Redox Biol
, vol.4
, pp. 184-192
-
-
Poillet-Perez, L.1
Despouy, G.2
Delage-Mourroux, R.3
Boyer-Guittaut, M.4
-
157
-
-
34247186472
-
Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4
-
[157] Scherz-Shouval, R., Shvets, E., Fass, E., Shorer, H., Gil, L., Elazar, Z., Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4. EMBO J 26 (2007), 1749–1760.
-
(2007)
EMBO J
, vol.26
, pp. 1749-1760
-
-
Scherz-Shouval, R.1
Shvets, E.2
Fass, E.3
Shorer, H.4
Gil, L.5
Elazar, Z.6
-
158
-
-
77749233738
-
ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS
-
[158] Alexander, A., Cai, S.L., Kim, J., Nanez, A., Sahin, M., MacLean, K.H., et al. ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS. Proc Natl Acad Sci USA 107 (2010), 4153–4158.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 4153-4158
-
-
Alexander, A.1
Cai, S.L.2
Kim, J.3
Nanez, A.4
Sahin, M.5
MacLean, K.H.6
-
159
-
-
77954599053
-
p62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription
-
[159] Jain, A., Lamark, T., Sjøttem, E., Larsen, K.B., Awuh, J.A., Øvervatn, A., et al. p62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription. J Biol Chem 285 (2010), 22576–22591.
-
(2010)
J Biol Chem
, vol.285
, pp. 22576-22591
-
-
Jain, A.1
Lamark, T.2
Sjøttem, E.3
Larsen, K.B.4
Awuh, J.A.5
Øvervatn, A.6
-
160
-
-
77649265091
-
The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1
-
[160] Komatsu, M., Kurokawa, H., Waguri, S., Taguchi, K., Kobayashi, A., Ichimura, Y., et al. The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1. Nat Cell Biol 12 (2010), 213–223.
-
(2010)
Nat Cell Biol
, vol.12
, pp. 213-223
-
-
Komatsu, M.1
Kurokawa, H.2
Waguri, S.3
Taguchi, K.4
Kobayashi, A.5
Ichimura, Y.6
-
161
-
-
84939787271
-
Transcriptional control of autophagy-lysosome function drives pancreatic cancer metabolism
-
[161] Perera, R.M., Stoykova, S., Nicolay, B.N., Ross, K.N., Fitamant, J., Boukhali, M., et al. Transcriptional control of autophagy-lysosome function drives pancreatic cancer metabolism. Nature 524 (2015), 361–365.
-
(2015)
Nature
, vol.524
, pp. 361-365
-
-
Perera, R.M.1
Stoykova, S.2
Nicolay, B.N.3
Ross, K.N.4
Fitamant, J.5
Boukhali, M.6
-
162
-
-
84934281252
-
p53 in survival, death and metabolic health: a lifeguard with a licence to kill
-
[162] Kruiswijk, F., Labuschagne, C.F., Vousden, K.H., p53 in survival, death and metabolic health: a lifeguard with a licence to kill. Nat Rev Mol Cell Biol 16 (2015), 393–405.
-
(2015)
Nat Rev Mol Cell Biol
, vol.16
, pp. 393-405
-
-
Kruiswijk, F.1
Labuschagne, C.F.2
Vousden, K.H.3
-
163
-
-
84918523488
-
Cancer metabolism and elevated O-GlcNAc in oncogenic signaling
-
[163] Ma, Z., Vosseller, K., Cancer metabolism and elevated O-GlcNAc in oncogenic signaling. J Biol Chem 289 (2014), 34457–34465.
-
(2014)
J Biol Chem
, vol.289
, pp. 34457-34465
-
-
Ma, Z.1
Vosseller, K.2
-
164
-
-
84875210462
-
Cardiac O-GlcNAcylation blunts autophagic signaling in the diabetic heart
-
[164] Marsh, S.A., Powell, P.C., Dell'italia, L.J., Chatham, J.C., Cardiac O-GlcNAcylation blunts autophagic signaling in the diabetic heart. Life Sci 92 (2013), 648–656.
-
(2013)
Life Sci
, vol.92
, pp. 648-656
-
-
Marsh, S.A.1
Powell, P.C.2
Dell'italia, L.J.3
Chatham, J.C.4
-
165
-
-
84925284243
-
O-GlcNAc-modification of SNAP-29 regulates autophagosome maturation
-
[165] Guo, B., Liang, Q., Li, L., Hu, Z., Wu, F., Zhang, P., et al. O-GlcNAc-modification of SNAP-29 regulates autophagosome maturation. Nat Cell Biol 16 (2014), 1215–1226.
-
(2014)
Nat Cell Biol
, vol.16
, pp. 1215-1226
-
-
Guo, B.1
Liang, Q.2
Li, L.3
Hu, Z.4
Wu, F.5
Zhang, P.6
-
166
-
-
84920080589
-
Regulation of autophagy by protein post-translational modification
-
[166] Wani, W.Y., Boyer-Guittaut, M., Dodson, M., Chatham, J., Darley-Usmar, V., Zhang, J., Regulation of autophagy by protein post-translational modification. Lab Invest 95 (2015), 14–25.
-
(2015)
Lab Invest
, vol.95
, pp. 14-25
-
-
Wani, W.Y.1
Boyer-Guittaut, M.2
Dodson, M.3
Chatham, J.4
Darley-Usmar, V.5
Zhang, J.6
-
167
-
-
84922783167
-
Glutathione and thioredoxin antioxidant pathways synergize to drive cancer initiation and progression
-
[167] Harris, I.S., Treloar, A.E., Inoue, S., Sasaki, M., Gorrini, C., Lee, K.C., et al. Glutathione and thioredoxin antioxidant pathways synergize to drive cancer initiation and progression. Cancer Cell 27 (2015), 211–222.
-
(2015)
Cancer Cell
, vol.27
, pp. 211-222
-
-
Harris, I.S.1
Treloar, A.E.2
Inoue, S.3
Sasaki, M.4
Gorrini, C.5
Lee, K.C.6
-
168
-
-
84858796263
-
IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype
-
[168] Turcan, S., Rohle, D., Goenka, A., Walsh, L.A., Fang, F., Yilmaz, E., et al. IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype. Nature 483 (2012), 479–483.
-
(2012)
Nature
, vol.483
, pp. 479-483
-
-
Turcan, S.1
Rohle, D.2
Goenka, A.3
Walsh, L.A.4
Fang, F.5
Yilmaz, E.6
|