메뉴 건너뛰기




Volumn 17, Issue 4, 2007, Pages 841-845

Transketolase protein TKTL1 overexpression: A potential biomarker and therapeutic target in breast cancer

Author keywords

Breast cancer; Transketolase like 1; Tumor metabolism; Warburg effect

Indexed keywords

TKTL1 PROTEIN, HUMAN; TRANSKETOLASE; TUMOR MARKER; UNCLASSIFIED DRUG;

EID: 34249942508     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.17.4.841     Document Type: Article
Times cited : (73)

References (29)
  • 1
    • 0000459772 scopus 로고
    • Über den Stoffwechsel der Carcinomzelle
    • Warburg O, Posener K, Negelein E: Über den Stoffwechsel der Carcinomzelle. Biochem Z 152: 309-344, 1924.
    • (1924) Biochem Z , vol.152 , pp. 309-344
    • Warburg, O.1    Posener, K.2    Negelein, E.3
  • 2
    • 11444261260 scopus 로고    scopus 로고
    • Energy boost: The Warburg effect returns in a new theory of cancer
    • Garber K: Energy boost: the Warburg effect returns in a new theory of cancer. J Natl Cancer Inst 96: 1805-1806, 2004.
    • (2004) J Natl Cancer Inst , vol.96 , pp. 1805-1806
    • Garber, K.1
  • 3
    • 8144228566 scopus 로고    scopus 로고
    • Why do cancers have high aerobic glycolysis?
    • DOI 10.1038/nrc1478
    • Gatenby RA and Gillies RJ: Why do cancers have high aerobic glycolysis? Nat Rev Cancer 4: 891-899, 2004. (Pubitemid 39472955)
    • (2004) Nature Reviews Cancer , vol.4 , Issue.11 , pp. 891-899
    • Gatenby, R.A.1    Gillies, R.J.2
  • 4
    • 21244460340 scopus 로고    scopus 로고
    • Mutations in the transketolase-like gene TKTL1: Clinical implications for neurodegenerative diseases, diabetes and cancer
    • Coy JF, Dressler D, Wilde J and Schubert P: Mutations in the transketolase-like gene TKTL1: clinical implications for neurodegenerative diseases, diabetes and cancer. Clin Lab 51: 257-273, 2005. (Pubitemid 40895125)
    • (2005) Clinical Laboratory , vol.51 , Issue.5-6 , pp. 257-273
    • Coy, J.F.1    Dressler, D.2    Wilde, J.3    Schubert, P.4
  • 8
    • 0032423288 scopus 로고    scopus 로고
    • Properties and functions of the thiamin diphosphate dependent enzyme transketolase
    • DOI 10.1016/S1357-2725(98)00095-8, PII S1357272598000958
    • Schenk G, Duggleby RG and Nixon PF: Properties and functions of the thiamin diphosphate dependent enzyme transketolase. Int J Biochem Cell Biol 30: 1297-1318, 1998. (Pubitemid 29002974)
    • (1998) International Journal of Biochemistry and Cell Biology , vol.30 , Issue.12 , pp. 1297-1318
    • Schenk, G.1    Duggleby, R.G.2    Nixon, P.F.3
  • 9
    • 0029976005 scopus 로고    scopus 로고
    • Molecular cloning of tissue-specific transcripts of a transketolase-related gene: Implications for the evolution of new vertebrate genes
    • Coy JF, Dubel S, Kioschis P, et al: Molecular cloning of tissue-specific transcripts of a transketolase-related gene: implications for the evolution of new vertebrate genes. Genomics 32: 309-316, 1996.
    • (1996) Genomics , vol.32 , pp. 309-316
    • Coy, J.F.1    Dubel, S.2    Kioschis, P.3
  • 12
    • 18644366801 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-1alpha and the glycolytic phenotype in tumors
    • DOI 10.1593/neo.04430
    • Robey IF, Lien AD, Welsh SJ, Baggett BK and Gillies RJ: Hypoxia-inducible factor-1alpha and the glycolytic phenotype in tumors. Neoplasia 7: 324-330, 2005. (Pubitemid 40664221)
    • (2005) Neoplasia , vol.7 , Issue.4 , pp. 324-330
    • Robey, I.F.1    Lien, A.D.2    Welsh, S.J.3    Baggett, B.K.4    Gillies, R.J.5
  • 14
    • 0034959513 scopus 로고    scopus 로고
    • Immunohistochemical expression of human erythrocyte glucose transporter and fatty acid synthase in infiltrating breast carcinomas and adjacent typical/atypical hyperplastic or normal breast tissue
    • Alo PL, Visca P, Botti C, et al: Immunohistochemical expression of human erythrocyte glucose transporter and fatty acid synthase in infiltrating breast carcinomas and adjacent typical/atypical hyperplastic or normal breast tissue. Am J Clin Pathol 116: 129-134, 2001.
    • (2001) Am J Clin Pathol , vol.116 , pp. 129-134
    • Alo, P.L.1    Visca, P.2    Botti, C.3
  • 15
    • 37049183697 scopus 로고
    • Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene
    • Slamon DJ, Clark GM, Wong SG, Levin WJ, Ullrich A and McGuire WL: Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science 235: 177-182, 1987. (Pubitemid 17231334)
    • (1987) Science , vol.235 , Issue.4785 , pp. 177-182
    • Slamon, D.J.1    Clark, G.M.2    Wong, S.G.3
  • 16
    • 0032078876 scopus 로고    scopus 로고
    • ERBB2 oncogene in human breast cancer and its clinical significance
    • DOI 10.1016/S0959-8049(97)10157-5, PII S0959804997101575
    • Revillion F, Bonneterre J and Peyrat JP: ERBB2 oncogene in human breast cancer and its clinical significance. Eur J Cancer 34: 791-808, 1998. (Pubitemid 28248487)
    • (1998) European Journal of Cancer , vol.34 , Issue.6 , pp. 791-808
    • Revillion, F.1    Bonneterre, J.2    Peyrat, J.P.3
  • 17
    • 12544256565 scopus 로고    scopus 로고
    • Inhibition of glycolysis in cancer cells: A novel strategy to overcome drug resistance associated with mitochondrial respiratory defect and hypoxia
    • Xu RH, Pelicano H, Zhou Y, et al: Inhibition of glycolysis in cancer cells: a novel strategy to overcome drug resistance associated with mitochondrial respiratory defect and hypoxia. Cancer Res 65: 613-621, 2005.
    • (2005) Cancer Res , vol.65 , pp. 613-621
    • Xu, R.H.1    Pelicano, H.2    Zhou, Y.3
  • 19
    • 20544449673 scopus 로고    scopus 로고
    • The glucose dependence of Akt-transformed cells can be reversed by pharmacologic activation of fatty acid beta-oxidation
    • DOI 10.1038/sj.onc.1208622
    • Buzzai M, Bauer DE, Jones RG, et al: The glucose dependence of Akt-transformed cells can be reversed by pharmacologic activation of fatty acid beta-oxidation. Oncogene 24: 4165-4173, 2005. (Pubitemid 40961771)
    • (2005) Oncogene , vol.24 , Issue.26 , pp. 4165-4173
    • Buzzai, M.1    Bauer, D.E.2    Jones, R.G.3    DeBerardinis, R.J.4    Hatzivassiliou, G.5    Elstrom, R.L.6    Thompson, C.B.7
  • 20
    • 0029009816 scopus 로고
    • Implementing a ketogenic diet based on medium-chain triglyceride oil in pediatric patients with cancer
    • Nebeling LC and Lerner E: Implementing a ketogenic diet based on medium-chain triglyceride oil in pediatric patients with cancer. J Am Diet Assoc 95: 693-697, 1995.
    • (1995) J Am Diet Assoc , vol.95 , pp. 693-697
    • Nebeling, L.C.1    Lerner, E.2
  • 21
    • 27744502691 scopus 로고    scopus 로고
    • Targeting energy metabolism in brain cancer: Review and hypothesis
    • Seyfried TN and Mukherjee P: Targeting energy metabolism in brain cancer: review and hypothesis. Nutr Metab 2: 30, 2005.
    • (2005) Nutr Metab , vol.2 , pp. 30
    • Seyfried, T.N.1    Mukherjee, P.2
  • 24
    • 0029991439 scopus 로고    scopus 로고
    • Phase II study of weekly intravenous recombinant humanized anti-p185HER2 monoclonal antibody in patients with HER2/neu-overexpressing metastatic breast cancer
    • Baselga J, Tripathy D, Mendelsohn J, et al: Phase II study of weekly intravenous recombinant humanized anti-p185HER2 monoclonal antibody in patients with HER2/neu-overexpressing metastatic breast cancer. J Clin Oncol 14: 737-744, 1996.
    • (1996) J Clin Oncol , vol.14 , pp. 737-744
    • Baselga, J.1    Tripathy, D.2    Mendelsohn, J.3
  • 27
    • 16644364379 scopus 로고    scopus 로고
    • Identification of novel small-molecule inhibitors for human transketolase by high-throughput screening with fluorescent intensity (FLINT) assay
    • Du MX, Sim J, Fang L, et al: Identification of novel small-molecule inhibitors for human transketolase by high-throughput screening with fluorescent intensity (FLINT) assay. J Biomol Screen 9: 427-433, 2004.
    • (2004) J Biomol Screen , vol.9 , pp. 427-433
    • Du, M.X.1    Sim, J.2    Fang, L.3
  • 28
    • 0034915207 scopus 로고    scopus 로고
    • Wheat germ extract decreases glucose uptake and RNA ribose formation but increases fatty acid synthesis in MIA pancreatic adenocarcinoma cells
    • DOI 10.1097/00006676-200108000-00004
    • Boros LG, Lapis K, Szende B, et al: Wheat germ extract decreases glucose uptake and RNA ribose formation but increases fatty acid synthesis in MIA pancreatic adenocarcinoma cells. Pancreas 23: 141-147, 2001. (Pubitemid 32692123)
    • (2001) Pancreas , vol.23 , Issue.2 , pp. 141-147
    • Boros, L.G.1    Lapis, K.2    Szende, B.3    Tomoskozi-Farkas, R.4    Balogh, A.5    Boren, J.6    Marin, S.7    Cascante, M.8    Hidvegi, M.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.