메뉴 건너뛰기




Volumn 120, Issue 11, 2010, Pages 3843-3854

Increased NOS2 predicts poor survival in estrogen receptor-negative breast cancer patients

Author keywords

[No Author keywords available]

Indexed keywords

ESTROGEN RECEPTOR; ESTROGEN RECEPTOR ALPHA; HERMES ANTIGEN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 8; MYC PROTEIN; TUMOR MARKER;

EID: 78049426509     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI42059     Document Type: Article
Times cited : (207)

References (79)
  • 1
    • 0035845511 scopus 로고    scopus 로고
    • Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
    • Sorlie T, et al. Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc Natl Acad Sci U S A. 2001;98(19):10869-10874.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , Issue.19 , pp. 10869-10874
    • Sorlie, T.1
  • 2
    • 38749117179 scopus 로고    scopus 로고
    • Prognostic effect of estrogen receptor status across age in primary breast cancer
    • DOI 10.1002/ijc.22892
    • Bentzon N, During M, Rasmussen BB, Mouridsen H, Kroman N. Prognostic effect of estrogen receptor status across age in primary breast cancer. Int J Cancer. 2008;122(5):1089-1094. (Pubitemid 351214007)
    • (2008) International Journal of Cancer , vol.122 , Issue.5 , pp. 1089-1094
    • Bentzon, N.1    During, M.2    Rasmussen, B.B.3    Mouridsen, H.4    Kroman, N.5
  • 3
    • 34248214791 scopus 로고    scopus 로고
    • Hormone receptor status, tumor characteristics, and prognosis: A prospective cohort of breast cancer patients
    • Dunnwald LK, Rossing MA, Li CI. Hormone receptor status, tumor characteristics, and prognosis: a prospective cohort of breast cancer patients. Breast Cancer Res. 2007;9(1):R6.
    • (2007) Breast Cancer Res , vol.9 , Issue.1
    • Dunnwald, L.K.1    Rossing, M.A.2    Li, C.I.3
  • 4
    • 0029816609 scopus 로고    scopus 로고
    • Association of macrophage infiltration with angiogenesis and prognosis in invasive breast carcinoma
    • Leek RD, Lewis CE, Whitehouse R, Greenall M, Clarke J, Harris AL. Association of macrophage infiltration with angiogenesis and prognosis in invasive breast carcinoma. Cancer Res. 1996;56(20):4625-4629. (Pubitemid 26338061)
    • (1996) Cancer Research , vol.56 , Issue.20 , pp. 4625-4629
    • Leek, R.D.1    Lewis, C.E.2    Whitehouse, R.3    Greenall, M.4    Clarke, J.5    Harris, A.L.6
  • 5
    • 40349094954 scopus 로고    scopus 로고
    • Inflammation and breast cancer. Balancing immune response: Crosstalk between adaptive and innate immune cells during breast cancer progression
    • Denardo DG, Coussens LM. Inflammation and breast cancer. Balancing immune response: crosstalk between adaptive and innate immune cells during breast cancer progression. Breast Cancer Res. 2007;9(4):212.
    • (2007) Breast Cancer Res , vol.9 , Issue.4 , pp. 212
    • Denardo, D.G.1    Coussens, L.M.2
  • 6
    • 0037180757 scopus 로고    scopus 로고
    • Inflammation and cancer
    • Coussens LM, Werb Z. Inflammation and cancer. Nature. 2002;420(6917):860-867.
    • (2002) Nature , vol.420 , Issue.6917 , pp. 860-867
    • Coussens, L.M.1    Werb, Z.2
  • 8
    • 0028092958 scopus 로고
    • Nitric oxide synthases: Roles, tolls, and controls
    • DOI 10.1016/0092-8674(94)90266-6
    • Nathan C, Xie QW. Nitric oxide synthases: roles, tolls, and controls. Cell. 1994;78(6):915-918. (Pubitemid 24292319)
    • (1994) Cell , vol.78 , Issue.6 , pp. 915-918
    • Nathan, C.1    Xie, Q.-W.2
  • 11
    • 0032171420 scopus 로고    scopus 로고
    • Chemical biology of nitric oxide: Insights into regulatory, cytotoxic, and cytoprotective mechanisms of nitric oxide
    • Wink DA, Mitchell JB. Chemical biology of nitric oxide: insights into regulatory, cytotoxic, and cytoprotective mechanisms of nitric oxide. Free Radic Biol Med. 1998;25(4-5):434-456.
    • (1998) Free Radic Biol Med , vol.25 , Issue.4-5 , pp. 434-456
    • Wink, D.A.1    Mitchell, J.B.2
  • 13
    • 0034083406 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase expression, apoptosis, and angiogenesis in in situ and invasive breast carcinomas
    • Vakkala M, Kahlos K, Lakari E, Paakko P, Kinnula V, Soini Y. Inducible nitric oxide synthase expression, apoptosis, and angiogenesis in in situ and invasive breast carcinomas. Clin Cancer Res. 2000;6(6):2408-2416. (Pubitemid 30399209)
    • (2000) Clinical Cancer Research , vol.6 , Issue.6 , pp. 2408-2416
    • Vakkala, M.1    Kahlos, K.2    Lakari, E.3    Paakko, P.4    Kinnula, V.5    Soini, Y.6
  • 19
    • 0030986262 scopus 로고    scopus 로고
    • Interactive effects of nitric oxide and the p53 tumor suppressor gene in carcinogenesis and tumor progression
    • Ambs S, Hussain SP, Harris CC. Interactive effects of nitric oxide and the p53 tumor suppressor gene in carcinogenesis and tumor progression. FASEB J. 1997;11(6):443-448.
    • (1997) FASEB J , vol.11 , Issue.6 , pp. 443-448
    • Ambs, S.1    Hussain, S.P.2    Harris, C.C.3
  • 21
    • 33846416533 scopus 로고    scopus 로고
    • Nitric oxide in physiologic concentrations targets the translational machinery to increase the proliferation of human breast cancer cells: Involvement of mammalian target of rapamycin/eIF4E pathway
    • Pervin S, Singh R, Hernandez E, Wu G, Chaudhuri G. Nitric oxide in physiologic concentrations targets the translational machinery to increase the proliferation of human breast cancer cells: involvement of mammalian target of rapamycin/eIF4E pathway. Cancer Res. 2007;67(1):289-299.
    • (2007) Cancer Res , vol.67 , Issue.1 , pp. 289-299
    • Pervin, S.1    Singh, R.2    Hernandez, E.3    Wu, G.4    Chaudhuri, G.5
  • 22
    • 33846600845 scopus 로고    scopus 로고
    • Inflammation and IGF-I activate the Akt pathway in breast cancer
    • Prueitt RL, et al. Inflammation and IGF-I activate the Akt pathway in breast cancer. Int J Cancer. 2007;120(4):796-805.
    • (2007) Int J Cancer , vol.120 , Issue.4 , pp. 796-805
    • Prueitt, R.L.1
  • 23
    • 0034488632 scopus 로고    scopus 로고
    • Nitric oxide synthase, cyclooxygenase 2, and vascular endothelial growth factor in the angiogenesis of non-small cell lung carcinoma
    • Marrogi AJ, et al. Nitric oxide synthase, cyclooxygenase 2, and vascular endothelial growth factor in the angiogenesis of non-small cell lung carcinoma. Clin Cancer Res. 2000;6(12):4739-4744.
    • (2000) Clin Cancer Res , vol.6 , Issue.12 , pp. 4739-4744
    • Marrogi, A.J.1
  • 25
    • 0032247368 scopus 로고    scopus 로고
    • Cox-2, iNOS and p53 as play-makers of tumor angiogenesis
    • Chiarugi V, Magnelli L, Gallo O. Cox-2, iNOS and p53 as play-makers of tumor angiogenesis. Int J Mol Med. 1998;2(6):715-719.
    • (1998) Int J Mol Med , vol.2 , Issue.6 , pp. 715-719
    • Chiarugi, V.1    Magnelli, L.2    Gallo, O.3
  • 27
    • 30944450821 scopus 로고    scopus 로고
    • Phenotypic evaluation of the basal-like subtype of invasive breast carcinoma
    • Livasy CA, et al. Phenotypic evaluation of the basal-like subtype of invasive breast carcinoma. Mod Pathol. 2006;19(2):264-271.
    • (2006) Mod Pathol , vol.19 , Issue.2 , pp. 264-271
    • Livasy, C.A.1
  • 28
    • 36349000534 scopus 로고    scopus 로고
    • Relationship of P-cadherin expression to basal phenotype of breast carcinoma
    • Potemski P, et al. Relationship of P-cadherin expression to basal phenotype of breast carcinoma. Pol J Pathol. 2007;58(3):183-188.
    • (2007) Pol J Pathol , vol.58 , Issue.3 , pp. 183-188
    • Potemski, P.1
  • 29
    • 33847663351 scopus 로고    scopus 로고
    • P-cadherin and cytokeratin 5: Useful adjunct markers to distinguish basal-like ductal carcinomas in situ
    • DOI 10.1007/s00428-006-0334-y
    • Paredes J, Lopes N, Milanezi F, Schmitt FC. P-cadherin and cytokeratin 5: useful adjunct markers to distinguish basal-like ductal carcinomas in situ. Virchows Arch. 2007;450(1):73-80. (Pubitemid 46360747)
    • (2007) Virchows Archiv , vol.450 , Issue.1 , pp. 73-80
    • Paredes, J.1    Lopes, N.2    Milanezi, F.3    Schmitt, F.C.4
  • 30
    • 31044441241 scopus 로고    scopus 로고
    • Gene expression profiling of breast cell lines identifies potential new basal markers
    • Charafe-Jauffret E, et al. Gene expression profiling of breast cell lines identifies potential new basal markers. Oncogene. 2006;25(15):2273-2284.
    • (2006) Oncogene , vol.25 , Issue.15 , pp. 2273-2284
    • Charafe-Jauffret, E.1
  • 32
    • 34447632167 scopus 로고    scopus 로고
    • Gene expression profiling spares early breast cancer patients from adjuvant therapy: Derived and validated in two population-based cohorts
    • Pawitan Y, et al. Gene expression profiling spares early breast cancer patients from adjuvant therapy: derived and validated in two population-based cohorts. Breast Cancer Res. 2005;7(6):R953-R964.
    • (2005) Breast Cancer Res , vol.7 , Issue.6
    • Pawitan, Y.1
  • 33
    • 66349114311 scopus 로고    scopus 로고
    • Nitric oxide induces early viral transcription coincident with increased DNA damage and mutation rates in human papillomavirus-infected cells
    • Wei L, Gravitt PE, Song H, Maldonado AM, Ozbun MA. Nitric oxide induces early viral transcription coincident with increased DNA damage and mutation rates in human papillomavirus-infected cells. Cancer Res. 2009;69(11):4878-4884.
    • (2009) Cancer Res , vol.69 , Issue.11 , pp. 4878-4884
    • Wei, L.1    Gravitt, P.E.2    Song, H.3    Maldonado, A.M.4    Ozbun, M.A.5
  • 36
    • 27644567107 scopus 로고    scopus 로고
    • p63, cytokeratin 5, and P-cadherin: Three molecular markers to distinguish basal phenotype in breast carcinomas
    • Matos I, Dufloth R, Alvarenga M, Zeferino LC, Schmitt F. p63, cytokeratin 5, and P-cadherin: three molecular markers to distinguish basal phenotype in breast carcinomas. Virchows Arch. 2005;447(4):688-694.
    • (2005) Virchows Arch , vol.447 , Issue.4 , pp. 688-694
    • Matos, I.1    Dufloth, R.2    Alvarenga, M.3    Zeferino, L.C.4    Schmitt, F.5
  • 37
    • 21344454219 scopus 로고    scopus 로고
    • Isolation and in vitro propagation of tumorigenic breast cancer cells with stem/progenitor cell properties
    • Ponti D, et al. Isolation and in vitro propagation of tumorigenic breast cancer cells with stem/progenitor cell properties. Cancer Res. 2005;65(13):5506-5511.
    • (2005) Cancer Res , vol.65 , Issue.13 , pp. 5506-5511
    • Ponti, D.1
  • 38
    • 0034326252 scopus 로고    scopus 로고
    • Effects of estrogen on global gene expression: Identification of novel targets of estrogen action
    • Charpentier AH, et al. Effects of estrogen on global gene expression: identification of novel targets of estrogen action. Cancer Res. 2000;60(21):5977-5983.
    • (2000) Cancer Res , vol.60 , Issue.21 , pp. 5977-5983
    • Charpentier, A.H.1
  • 39
    • 42649112047 scopus 로고    scopus 로고
    • An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors
    • Ben Porath I, et al. An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors. Nat Genet. 2008;40(5):499-507.
    • (2008) Nat Genet , vol.40 , Issue.5 , pp. 499-507
    • Ben Porath, I.1
  • 40
    • 55749104730 scopus 로고    scopus 로고
    • The CD44+/CD24- Phenotype is enriched in basal-like breast tumors
    • Honeth G, et al. The CD44+/CD24- phenotype is enriched in basal-like breast tumors. Breast Cancer Res. 2008;10(3):R53.
    • (2008) Breast Cancer Res , vol.10 , Issue.3
    • Honeth, G.1
  • 42
    • 23744465234 scopus 로고    scopus 로고
    • Significance of inducible nitric oxide synthase expression in benign and malignant breast epithelium: An immunohistochemical study of 151 cases
    • Bulut AS, Erden E, Sak SD, Doruk H, Kursun N, Dincol D. Significance of inducible nitric oxide synthase expression in benign and malignant breast epithelium: an immunohistochemical study of 151 cases. Virchows Arch. 2005;447(1):24-30.
    • (2005) Virchows Arch , vol.447 , Issue.1 , pp. 24-30
    • Bulut, A.S.1    Erden, E.2    Sak, S.D.3    Doruk, H.4    Kursun, N.5    Dincol, D.6
  • 43
    • 0038207007 scopus 로고    scopus 로고
    • Mammary tumor latency is increased in mice lacking the inducible nitric oxide synthase
    • Ellies LG, et al. Mammary tumor latency is increased in mice lacking the inducible nitric oxide synthase. Int J Cancer. 2003;106(1):1-7.
    • (2003) Int J Cancer , vol.106 , Issue.1 , pp. 1-7
    • Ellies, L.G.1
  • 44
    • 11844301247 scopus 로고    scopus 로고
    • Expression of nitric oxide synthase in human gastric carcinoma and its relation to p53, PCNA
    • Wang YZ, Cao YQ, Wu JN, Chen M, Cha XY. Expression of nitric oxide synthase in human gastric carcinoma and its relation to p53, PCNA. World J Gastroenterol. 2005;11(1):46-50.
    • (2005) World J Gastroenterol , vol.11 , Issue.1 , pp. 46-50
    • Wang, Y.Z.1    Cao, Y.Q.2    Wu, J.N.3    Chen, M.4    Cha, X.Y.5
  • 45
    • 33747892706 scopus 로고    scopus 로고
    • Expression of inducible nitric oxide synthase and cyclooxygenase-2 in angiogenesis and clinical outcome of human gastric cancer
    • Chen CN, Hsieh FJ, Cheng YM, Chang KJ, Lee PH. Expression of inducible nitric oxide synthase and cyclooxygenase-2 in angiogenesis and clinical outcome of human gastric cancer. J Surg Oncol. 2006;94(3):226-233.
    • (2006) J Surg Oncol , vol.94 , Issue.3 , pp. 226-233
    • Chen, C.N.1    Hsieh, F.J.2    Cheng, Y.M.3    Chang, K.J.4    Lee, P.H.5
  • 46
    • 0037213991 scopus 로고    scopus 로고
    • Association between inducible nitric oxide synthase expression and p53 status in human esophageal squamous cell carcinoma
    • Matsumoto M, Furihata M, Kurabayashi A, Araki K, Sasaguri S, Ohtsuki Y. Association between inducible nitric oxide synthase expression and p53 status in human esophageal squamous cell carcinoma. Oncology. 2003;64(1):90-96.
    • (2003) Oncology , vol.64 , Issue.1 , pp. 90-96
    • Matsumoto, M.1    Furihata, M.2    Kurabayashi, A.3    Araki, K.4    Sasaguri, S.5    Ohtsuki, Y.6
  • 47
    • 39149132505 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase: Correlation with extracapsular spread and enhancement of tumor cell invasion in head and neck squamous cell carcinoma
    • Brennan PA, Dennis S, Poller D, Quintero M, Puxeddu R, Thomas GJ. Inducible nitric oxide synthase: correlation with extracapsular spread and enhancement of tumor cell invasion in head and neck squamous cell carcinoma. Head Neck. 2008;30(2):208-214.
    • (2008) Head Neck , vol.30 , Issue.2 , pp. 208-214
    • Brennan, P.A.1    Dennis, S.2    Poller, D.3    Quintero, M.4    Puxeddu, R.5    Thomas, G.J.6
  • 48
    • 0029079394 scopus 로고
    • Roles of nitric oxide in tumor growth
    • Jenkins DC, et al. Roles of nitric oxide in tumor growth. Proc Natl Acad Sci U S A. 1995;92(10):4392-4396.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , Issue.10 , pp. 4392-4396
    • Jenkins, D.C.1
  • 49
    • 0028143547 scopus 로고
    • Nitric oxide mediates angiogenesis in vivo and endothelial cell growth and migration in vitro promoted by substance P
    • Ziche M, et al. Nitric oxide mediates angiogenesis in vivo and endothelial cell growth and migration in vitro promoted by substance P. J Clin Invest. 1994;94(5):2036-2044.
    • (1994) J Clin Invest , vol.94 , Issue.5 , pp. 2036-2044
    • Ziche, M.1
  • 51
    • 0030808955 scopus 로고    scopus 로고
    • Nitric oxide induces conformational and functional modifications of wild-type p53 tumor suppressor protein
    • Calmels S, Hainaut P, Ohshima H. Nitric oxide induces conformational and functional modifications of wild-type p53 tumor suppressor protein. Cancer Res. 1997;57(16):3365-3369.
    • (1997) Cancer Res , vol.57 , Issue.16 , pp. 3365-3369
    • Calmels, S.1    Hainaut, P.2    Ohshima, H.3
  • 52
    • 0345564811 scopus 로고    scopus 로고
    • Atypical methylation of the interleukin-8 gene correlates strongly with the metastatic potential of breast carcinoma cells
    • de Larco JE, Wuertz BR, Yee D, Rickert BL, Furcht LT. Atypical methylation of the interleukin-8 gene correlates strongly with the metastatic potential of breast carcinoma cells. Proc Natl Acad Sci U S A. 2003;100(24):13988-13993.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , Issue.24 , pp. 13988-13993
    • De Larco, J.E.1    Wuertz, B.R.2    Yee, D.3    Rickert, B.L.4    Furcht, L.T.5
  • 53
    • 0034828008 scopus 로고    scopus 로고
    • Regulation of interleukin-8 expression by nitric oxide in human pancreatic adenocarcinoma
    • Xiong Q, Shi Q, Le X, Wang B, Xie K. Regulation of interleukin-8 expression by nitric oxide in human pancreatic adenocarcinoma. J Interferon Cytokine Res. 2001;21(7):529-537.
    • (2001) J Interferon Cytokine Res , vol.21 , Issue.7 , pp. 529-537
    • Xiong, Q.1    Shi, Q.2    Le, X.3    Wang, B.4    Xie, K.5
  • 54
    • 3042784053 scopus 로고    scopus 로고
    • Nitric oxide post-transcriptionally upregulates LPS-induced IL-8 expression through p38 MAPK activation
    • Ma P, et al. Nitric oxide post-transcriptionally upregulates LPS-induced IL-8 expression through p38 MAPK activation. J Leukoc Biol. 2004;76(1):278-287.
    • (2004) J Leukoc Biol , vol.76 , Issue.1 , pp. 278-287
    • Ma, P.1
  • 55
    • 4544257935 scopus 로고    scopus 로고
    • Nitric oxide increases IL-8 gene transcription and mRNA stability to enhance IL-8 gene expression in lung epithelial cells
    • Sparkman L, Boggaram V. Nitric oxide increases IL-8 gene transcription and mRNA stability to enhance IL-8 gene expression in lung epithelial cells. Am J Physiol Lung Cell Mol Physiol. 2004;287(4):L764-L773.
    • (2004) Am J Physiol Lung Cell Mol Physiol , vol.287 , Issue.4
    • Sparkman, L.1    Boggaram, V.2
  • 56
    • 0022455952 scopus 로고
    • Oestrogen receptor concentration and macrophage infiltration in human breast cancer
    • Steele RJ, Eremin O, Brown M, Hawkins RA. Oestrogen receptor concentration and macrophage infiltration in human breast cancer. Eur J Surg Oncol. 1986;12(3):273-276.
    • (1986) Eur J Surg Oncol , vol.12 , Issue.3 , pp. 273-276
    • Steele, R.J.1    Eremin, O.2    Brown, M.3    Hawkins, R.A.4
  • 57
    • 8444230395 scopus 로고    scopus 로고
    • Increased serum interleukin-8 in patients with early and metastatic breast cancer correlates with early dissemination and survival
    • Benoy IH, et al. Increased serum interleukin-8 in patients with early and metastatic breast cancer correlates with early dissemination and survival. Clin Cancer Res. 2004;10(21):7157-7162.
    • (2004) Clin Cancer Res , vol.10 , Issue.21 , pp. 7157-7162
    • Benoy, I.H.1
  • 58
    • 60549111070 scopus 로고    scopus 로고
    • Breast cancer cell lines contain functional cancer stem cells with metastatic capacity and a distinct molecular signature
    • Charafe-Jauffret E, et al. Breast cancer cell lines contain functional cancer stem cells with metastatic capacity and a distinct molecular signature. Cancer Res. 2009;69(4):1302-1313.
    • (2009) Cancer Res , vol.69 , Issue.4 , pp. 1302-1313
    • Charafe-Jauffret, E.1
  • 59
    • 0037453240 scopus 로고    scopus 로고
    • 17 beta-estradiol increases inducible nitric oxide synthase expression in macrophages
    • You HJ, Kim JY, Jeong HG. 17 beta-estradiol increases inducible nitric oxide synthase expression in macrophages. Biochem Biophys Res Commun. 2003;303(4):1129-1134.
    • (2003) Biochem Biophys Res Commun , vol.303 , Issue.4 , pp. 1129-1134
    • You, H.J.1    Kim, J.Y.2    Jeong, H.G.3
  • 60
    • 73349094392 scopus 로고    scopus 로고
    • Estrogen regulates transcription factors STAT-1 and NF-kappaB to promote inducible nitric oxide synthase and inflammatory responses
    • Dai R, Phillips RA, Karpuzoglu E, Khan D, Ahmed SA. Estrogen regulates transcription factors STAT-1 and NF-kappaB to promote inducible nitric oxide synthase and inflammatory responses. J Immunol. 2009;183(11):6998-7005.
    • (2009) J Immunol , vol.183 , Issue.11 , pp. 6998-7005
    • Dai, R.1    Phillips, R.A.2    Karpuzoglu, E.3    Khan, D.4    Ahmed, S.A.5
  • 61
    • 56849130580 scopus 로고    scopus 로고
    • Differential regulation of the inducible nitric oxide synthase gene by estrogen receptors 1 and 2
    • Tsutsumi S, et al. Differential regulation of the inducible nitric oxide synthase gene by estrogen receptors 1 and 2. J Endocrinol. 2008;199(2):267-273.
    • (2008) J Endocrinol , vol.199 , Issue.2 , pp. 267-273
    • Tsutsumi, S.1
  • 62
    • 0030061515 scopus 로고    scopus 로고
    • Transcriptional regulation of human inducible nitric oxide synthase (NOS2) gene by cytokines: Initial analysis of the human NOS2 promoter
    • de Vera ME, et al. Transcriptional regulation of human inducible nitric oxide synthase (NOS2) gene by cytokines: initial analysis of the human NOS2 promoter. Proc Natl Acad Sci U S A. 1996;93(3):1054-1059.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , Issue.3 , pp. 1054-1059
    • De Vera, M.E.1
  • 63
    • 34248148710 scopus 로고    scopus 로고
    • Oestrogen receptor negative breast cancers exhibit high cytokine content
    • Chavey C, et al. Oestrogen receptor negative breast cancers exhibit high cytokine content. Breast Cancer Res. 2007;9(1):R15.
    • (2007) Breast Cancer Res , vol.9 , Issue.1
    • Chavey, C.1
  • 64
    • 78049442767 scopus 로고    scopus 로고
    • Numb protein expression correlates with a basal-like phenotype and cancer stem cell markers in primary breast cancer
    • Rennstam K, et al. Numb protein expression correlates with a basal-like phenotype and cancer stem cell markers in primary breast cancer. Breast Cancer Res. 2009;9(1):R15.
    • (2009) Breast Cancer Res , vol.9 , Issue.1
    • Rennstam, K.1
  • 65
    • 77955552069 scopus 로고    scopus 로고
    • The prognostic role of cancer stem cells in breast cancer: A meta-analysis of published literatures
    • Zhou L, et al. The prognostic role of cancer stem cells in breast cancer: a meta-analysis of published literatures. Breast Cancer Res Treat. 2010;122(3):795-801.
    • (2010) Breast Cancer Res Treat , vol.122 , Issue.3 , pp. 795-801
    • Zhou, L.1
  • 66
    • 33751346643 scopus 로고    scopus 로고
    • CD44+/CD24- Breast cancer cells exhibit enhanced invasive properties: An early step necessary for metastasis
    • Sheridan C, et al. CD44+/CD24- breast cancer cells exhibit enhanced invasive properties: an early step necessary for metastasis. Breast Cancer Res. 2006;8(5):R59.
    • (2006) Breast Cancer Res , vol.8 , Issue.5
    • Sheridan, C.1
  • 67
    • 33845904383 scopus 로고    scopus 로고
    • The response of CD24(-/low)/CD44+ breast cancer-initiating cells to radiation
    • Phillips TM, McBride WH, Pajonk F. The response of CD24(-/low)/CD44+ breast cancer-initiating cells to radiation. J Natl Cancer Inst. 2006;98(24):1777-1785.
    • (2006) J Natl Cancer Inst , vol.98 , Issue.24 , pp. 1777-1785
    • Phillips, T.M.1    McBride, W.H.2    Pajonk, F.3
  • 68
    • 47749116454 scopus 로고    scopus 로고
    • Hyaluronan-CD44 interaction activates stem cell marker Nanog, Stat-3-mediated MDR1 gene expression, and ankyrin-regulated multidrug efflux in breast and ovarian tumor cells
    • Bourguignon LY, Peyrollier K, Xia W, Gilad E. Hyaluronan-CD44 interaction activates stem cell marker Nanog, Stat-3-mediated MDR1 gene expression, and ankyrin-regulated multidrug efflux in breast and ovarian tumor cells. J Biol Chem. 2008;283(25):17635-17651.
    • (2008) J Biol Chem , vol.283 , Issue.25 , pp. 17635-17651
    • Bourguignon, L.Y.1    Peyrollier, K.2    Xia, W.3    Gilad, E.4
  • 69
    • 50349092591 scopus 로고    scopus 로고
    • Activation of epidermal growth factor receptor and its downstream signaling pathway by nitric oxide in response to ionizing radiation
    • Lee HC, et al. Activation of epidermal growth factor receptor and its downstream signaling pathway by nitric oxide in response to ionizing radiation. Mol Cancer Res. 2008;6(6):996-1002.
    • (2008) Mol Cancer Res , vol.6 , Issue.6 , pp. 996-1002
    • Lee, H.C.1
  • 70
    • 20444423286 scopus 로고    scopus 로고
    • Nuclear interaction of EGFR and STAT3 in the activation of the iNOS/NO pathway
    • Lo HW, et al. Nuclear interaction of EGFR and STAT3 in the activation of the iNOS/NO pathway. Cancer Cell. 2005;7(6):575-589.
    • (2005) Cancer Cell , vol.7 , Issue.6 , pp. 575-589
    • Lo, H.W.1
  • 71
    • 31444440292 scopus 로고    scopus 로고
    • Nuclear EGFR signalling network in cancers: Linking EGFR pathway to cell cycle progression, nitric oxide pathway and patient survival
    • Lo HW, Hung MC. Nuclear EGFR signalling network in cancers: linking EGFR pathway to cell cycle progression, nitric oxide pathway and patient survival. Br J Cancer. 2006;94(2):184-188.
    • (2006) Br J Cancer , vol.94 , Issue.2 , pp. 184-188
    • Lo, H.W.1    Hung, M.C.2
  • 72
    • 39649088238 scopus 로고    scopus 로고
    • A stromal gene signature associated with inflammatory breast cancer
    • Boersma BJ, et al. A stromal gene signature associated with inflammatory breast cancer. Int J Cancer. 2007;122(6):1324-1332.
    • (2007) Int J Cancer , vol.122 , Issue.6 , pp. 1324-1332
    • Boersma, B.J.1
  • 73
    • 32444445937 scopus 로고    scopus 로고
    • Breast cancer staging: Working with the sixth edition of the AJCC Cancer Staging Manual
    • Singletary SE, Connolly JL. Breast cancer staging: working with the sixth edition of the AJCC Cancer Staging Manual. CA Cancer J Clin. 2006;56(1):37-47.
    • (2006) CA Cancer J Clin , vol.56 , Issue.1 , pp. 37-47
    • Singletary, S.E.1    Connolly, J.L.2
  • 74
    • 0026072872 scopus 로고
    • Pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: Experience from a large study with long-term follow-up
    • Elston CW, Ellis IO. Pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: experience from a large study with long-term follow-up. Histopathology. 1991;19(5):403-410.
    • (1991) Histopathology , vol.19 , Issue.5 , pp. 403-410
    • Elston, C.W.1    Ellis, I.O.2
  • 75
    • 0026083903 scopus 로고
    • Tumor angiogenesis and metastasis - Correlation in invasive breast carcinoma
    • Weidner N, Semple JP, Welch WR, Folkman J. Tumor angiogenesis and metastasis - correlation in invasive breast carcinoma. N Engl J Med. 1991;324(1):1-8.
    • (1991) N Engl J Med , vol.324 , Issue.1 , pp. 1-8
    • Weidner, N.1    Semple, J.P.2    Welch, W.R.3    Folkman, J.4
  • 76
    • 33745783716 scopus 로고    scopus 로고
    • Association of breast cancer outcome with status of p53 and MDM2 SNP309
    • Boersma BJ, et al. Association of breast cancer outcome with status of p53 and MDM2 SNP309. J Natl Cancer Inst. 2006;98(13):911-919.
    • (2006) J Natl Cancer Inst , vol.98 , Issue.13 , pp. 911-919
    • Boersma, B.J.1
  • 77
    • 28744458859 scopus 로고    scopus 로고
    • Bioconductor: Open software development for computational biology and bioinformatics
    • Gentleman RC, et al. Bioconductor: open software development for computational biology and bioinformatics. Genome Biol. 2004;5(10):R80.
    • (2004) Genome Biol , vol.5 , Issue.10
    • Gentleman, R.C.1
  • 78
    • 0042424602 scopus 로고    scopus 로고
    • Statistical significance for genomewide studies
    • Storey JD, Tibshirani R. Statistical significance for genomewide studies. Proc Natl Acad Sci U S A. 2003;100(16):9440-9445.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , Issue.16 , pp. 9440-9445
    • Storey, J.D.1    Tibshirani, R.2
  • 79
    • 39749120859 scopus 로고    scopus 로고
    • The 3-hydroxy-3-methylglutarylcoenzyme a reductase inhibitors, simvastatin, lovastatin and mevastatin inhibit proliferation and invasion of melanoma cells
    • Glynn SA, O'Sullivan D, Eustace AJ, Clynes M, O'Donovan N. The 3-hydroxy-3-methylglutarylcoenzyme A reductase inhibitors, simvastatin, lovastatin and mevastatin inhibit proliferation and invasion of melanoma cells. BMC Cancer. 2008;8:9.
    • (2008) BMC Cancer , vol.8 , pp. 9
    • Glynn, S.A.1    O'Sullivan, D.2    Eustace, A.J.3    Clynes, M.4    O'Donovan, N.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.