High expression of gabarapl1 is associated with a better outcome for patients with lymph node-positive breast cancer

British Journal of Cancer

Volumn 102, Issue 6, 2010, Pages 1024-1031

  Berthier, A ^a   Seguin, S ^a   Sasco, A J ^b   Bobin, J Y ^c   De Laroche, G ^d   Datchary, J ^e   Saez, S ^c   Rodriguez Lafrasse, C ^c   Tolle, F ^a   Fraichard, A ^a   Boyer Guittaut, M ^a   Jouvenot, M ^a   Delage Mourroux, R ^a   Descotes, F ^c  

^a UNIVERSITÉ DE FRANCHE COMTÉ   (France)

^b INSERM   (France)

^c CENTRE HOSPITALIER LYON SUD   (France)

^d Clinique Mutualiste   (France)

^e Centre Hospitalier de la Region d'Annecy   (France)

Author keywords

Breast cancer; Gabarapl1; Lymph node positive; Prognosis

Indexed keywords

ESTROGEN RECEPTOR; GABA A RECEPTOR ASSOCIATED PROTEIN LIKE 1; MICROTUBULE ASSOCIATED PROTEIN; PROGESTERONE RECEPTOR; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; BREAST CANCER; CANCER GROWTH; CELL STRAIN MCF 7; CONTROLLED STUDY; DOWN REGULATION; GENE OVEREXPRESSION; GENETIC ASSOCIATION; HUMAN; HUMAN CELL; HUMAN TISSUE; LYMPH NODE; MAJOR CLINICAL STUDY; METASTASIS; NUCLEOTIDE SEQUENCE; OUTCOME ASSESSMENT; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADULT; AGED; AGED, 80 AND OVER; BREAST NEOPLASMS; CARCINOMA, DUCTAL, BREAST; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LYMPH NODES; LYMPHATIC METASTASIS; MICROTUBULE-ASSOCIATED PROTEINS; MIDDLE AGED; OUTCOME ASSESSMENT (HEALTH CARE); PROGNOSIS; RECURRENCE; RETROSPECTIVE STUDIES; TUMOR CELLS, CULTURED; TUMOR MARKERS, BIOLOGICAL; UP-REGULATION;

EID: 77949541314     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/sj.bjc.6605568     Document Type: Article

References (18)

1. Aapro MS (2001) Adjuvant therapy of primary breast cancer: a review of key findings from the 7th International Conference, St Gallen, February 2001. Oncologist 6: 376-385
2. Berthier A, Girard C, Grandvuillemin A, Muyard F, Skaltsounis AL, Jouvenot M, Delage-Mourroux R (2007) Effect of 7-O-beta-D-glucopyr-anosylchrysin and its aglycone chrysin isolated from Podocytisus caramanicus on estrogen receptor alpha transcriptional activity. Planta Med 73: 1447-1451
3. Bloom HJ, Richardson WW (1957) Histological grading and prognosis in breast cancer; a study of 1409 cases of which 359 have been followed for 15 years. Br J Cancer 11: 359-377
4. Chen C, Li JG, Chen Y, Huang P, Wang Y, Liu-Chen LY (2006) GEC1 interacts with the kappa opioid receptor and enhances expression of the receptor. J Biol Chem 281: 7983-7993
5. Descotes F, Riche B, Saez S, De Laroche G, Datchary J, Roy P, André J, Bobin JY (2008) Plasminogen activator inhibitor type 1 is the most significant of the usual tissue prognostic factors in node-negative breast ductal adenocarcinoma independent of urokinase-type plasminogen activator. Clin Breast Cancer 8: 168-177
6. EORTC (1980) Revision of the standards for the assessment of hormone receptors in human breast cancer; report of the second E.O.R.T.C. Workshop, held on 16-17 March, 1979, in the Netherlands Cancer Institute. Eur J Cancer 16: 1513-1515
7. Klebig C, Seitz S, Arnold W, Deutschmann N, Pacyna-Gengelbach M, Scherneck S, Petersen I (2005) Characterization of \{gamma\}-aminobu-tyric acid type A receptor-associated protein, a novel tumor suppressor, showing reduced expression in breast cancer. Cancer Res 65: 394-400
8. Lo PK, Sukumar S (2008) Epigenomics and breast cancer. Pharmacoge-nomics 9: 1879-1902
9. Mansuy V, Boireau W, Fraichard A, Schlick JL, Jouvenot M, Delage-Mourroux R (2004) GEC1, a protein related to GABARAP, interacts with tubulin and GABA(A) receptor. Biochem Biophys Res Commun 325: 639-648
10. Morel C, Adami P, Musard JF, Duval D, Radom J, Jouvenot M (2007) Involvement of sulfhydryl oxidase QSOX1 in the protection of cells against oxidative stress-induced apoptosis. Exp Cell Res 313: 3971-3982
11. Nemos C, Mansuy V, Vernier-Magnin S, Fraichard A, Jouvenot M, Delage-Mourroux R (2003) Expression of gec1/GABARAPL1 vs GABARAP mRNAs in human: predominance of gec1/GABARAPL1 in the central nervous system. Brain Res Mol Brain Res 119: 216-219
12. Pellerin I, Vuillermoz C, Jouvenot M, Ordener C, Royez M, Adessi GL (1993) Identification and characterization of an early estrogen-regulated RNA in cultured guinea-pig endometrial cells. Mol Cell Endocrinol 90: R17-R21
13. Roberts SS, Mori M, Pattee P, Lapidus J, Mathews R, O'Malley JP, Hsieh YC, Turner MA, Wang Z, Tian Q, Rodland MJ, Reynolds CP, Seeger RC, Nagalla SR (2004) GABAergic system gene expression predicts clinical outcome in patients with neuroblastoma. J Clin Oncol 22: 4127-4134
14. Sasco AJ, Kaaks R, Little RE (2003) Breast cancer: occurrence, risk factors and hormone metabolism. Expert Rev Anticancer Ther 3: 546-562
15. Sobin LH, Wittekind C (eds) (1997) Breast tumours (ICD-O C50). In TNM Classification of Malignant Tumours, 5 edn, pp 123-130. Wiley-Liss: New York
16. Tolle F, Risold PY, Mansuy-Schlick V, Rossi E, Boyer-Guittaut M, Fraichard A, Jouvenot M (2008) Specific regional distribution of gec1 mRNAs in adult rat central nervous system. Brain Res 1210: 103-115
17. Tomlinson IP (2001) Mutations in normal breast tissue and breast tumours. Breast Cancer Res 3: 299-303
18. Towbin H, Staehelin T, Gordon J (1979) Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci USA 76: 4350-4354