c-Myc can induce DNA damage, increase reactive oxygen species, and mitigate p53 function: A mechanism for oncogene-induced genetic instability

Molecular Cell

Volumn 9, Issue 5, 2002, Pages 1031-1044

  Vafa, Omid ^a   Wade, Mark ^a   Kern, Suzanne ^b   Beeche, Michelle ^a   Pandita, Tej K ^c   Hampton, Garret M ^b   Wahl, Geoffrey M ^a  

^a SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^b GENOMICS INSTITUTE OF THE NOVARTIS RESEARCH FOUNDATION   (United States)

^c Columbia University ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT; PROTEIN P53; REACTIVE OXYGEN METABOLITE;

APOPTOSIS; ARTICLE; BIOCHEMISTRY; CANCER GROWTH; CELL CYCLE S PHASE; CELL METABOLISM; CELL SURVIVAL; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOLOGY; DNA DAMAGE; FIBROBLAST; GENE ACTIVATION; GENE EXPRESSION; GENE FUNCTION; GENE INACTIVATION; GENETIC STABILITY; HUMAN; HUMAN CELL; ONCOGENE C MYC; PROTEIN INDUCTION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

EID: 0036285034     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1097-2765(02)00520-8     Document Type: Article

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