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Volumn 37, Issue 3, 2014, Pages 99-105

Cell culture, oxidative stress, and antioxidants: Avoiding pitfalls

Author keywords

antioxidant; ascorbate; cell culture; flavonoid; oxidative stress; oxygen radicals

Indexed keywords

ANTIOXIDANT; ASCORBIC ACID; CAROTENOID; POLYPHENOL; REACTIVE OXYGEN METABOLITE; CULTURE MEDIUM;

EID: 84902462980     PISSN: 23194170     EISSN: None     Source Type: Journal    
DOI: 10.4103/2319-4170.128725     Document Type: Article
Times cited : (196)

References (83)
  • 1
    • 0037430971 scopus 로고    scopus 로고
    • Oxidative stress in cell culture: An under-appreciated problem
    • Halliwell B. Oxidative stress in cell culture: An under-appreciated problem. FEBS Lett 2003;540:3-6.
    • (2003) FEBS Lett , vol.540 , pp. 3-6
    • Halliwell, B.1
  • 2
    • 78649441057 scopus 로고    scopus 로고
    • Stem Cells. Diseases in a dish take off
    • Vogel G. Stem Cells. Diseases in a dish take off. Science 2010;330:1172-3.
    • (2010) Science , vol.330 , pp. 1172-1173
    • Vogel, G.1
  • 3
    • 84887093048 scopus 로고    scopus 로고
    • How do immune cells support and shape the brain in health, disease, and aging?
    • Schwartz M, Kipnis J, Rivest S, Prat A. How do immune cells support and shape the brain in health, disease, and aging? J Neurosci 2013;33:17587-96.
    • (2013) J Neurosci , vol.33 , pp. 17587-17596
    • Schwartz, M.1    Kipnis, J.2    Rivest, S.3    Prat, A.4
  • 4
    • 54349093985 scopus 로고    scopus 로고
    • Curbing rampant cross-contamination and misidentification of cell lines
    • Nardone RM. Curbing rampant cross-contamination and misidentification of cell lines. Biotechniques 2008;45:221-7.
    • (2008) Biotechniques , vol.45 , pp. 221-227
    • Nardone, R.M.1
  • 5
    • 77952950455 scopus 로고    scopus 로고
    • Cell line misidentification: The beginning of the end
    • American Type Culture Collection Standards Development Organization Workgroup ASN-0002
    • American Type Culture Collection Standards Development Organization Workgroup ASN-0002. Cell line misidentification: The beginning of the end. Nat Rev Cancer 2010;10:441-8.
    • (2010) Nat Rev Cancer , vol.10 , pp. 441-448
  • 7
    • 77956110148 scopus 로고    scopus 로고
    • Cell biology. to scientists' dismay. Mixed-up cell lines strike again
    • Vogel G. Cell biology. To scientists' dismay. Mixed-up cell lines strike again. Science 2010;329:1004.
    • (2010) Science , vol.329 , pp. 1004
    • Vogel, G.1
  • 10
    • 84888331810 scopus 로고    scopus 로고
    • Variability in APOE genotype status in human-derived cell lines: A cause for concern in cell culture studies?
    • Schaffer S, Lam YM, Ernst IM, Huebbe P, Rimbach G, Halliwell B. Variability in APOE genotype status in human-derived cell lines: A cause for concern in cell culture studies? Genes Nutr 2014;9:364.
    • (2014) Genes Nutr , vol.9 , pp. 364
    • Schaffer, S.1    Lam, Y.M.2    Ernst, I.M.3    Huebbe, P.4    Rimbach, G.5    Halliwell, B.6
  • 11
    • 84873182675 scopus 로고    scopus 로고
    • The role of ROS toxicity in spontaneous aneuploidy in cultured cells
    • Wang CY, Liu LN, Zhao ZB. The role of ROS toxicity in spontaneous aneuploidy in cultured cells. Tissue Cell 2013;45:47-53.
    • (2013) Tissue Cell , vol.45 , pp. 47-53
    • Wang, C.Y.1    Liu, L.N.2    Zhao, Z.B.3
  • 12
    • 84884163460 scopus 로고    scopus 로고
    • HeLa genome versus donor's genome
    • Heng HH. HeLa genome versus donor's genome. Nature 2013;501:167.
    • (2013) Nature , vol.501 , pp. 167
    • Heng, H.H.1
  • 14
    • 0035989631 scopus 로고    scopus 로고
    • Historical claims and current interpretations of replicative ageing
    • Wright WE, Shay JY. Historical claims and current interpretations of replicative ageing. Nat Biotechnol 2002;20:682-8.
    • (2002) Nat Biotechnol , vol.20 , pp. 682-688
    • Wright, W.E.1    Shay, J.Y.2
  • 15
    • 0342545974 scopus 로고    scopus 로고
    • Peroxynitrite generated from constitutive nitric oxide synthase mediates the early biochemical injury in short-term cultured hepatocytes
    • López-García MP, Sanz-González SM. Peroxynitrite generated from constitutive nitric oxide synthase mediates the early biochemical injury in short-term cultured hepatocytes. FEBS Lett 2000;466:187-91.
    • (2000) FEBS Lett , vol.466 , pp. 187-191
    • López-García, M.P.1    Sanz-González, S.M.2
  • 16
    • 0034685678 scopus 로고    scopus 로고
    • Depletion of cellular glutathione by conditions used for the passaging of adherent cultured cells
    • Reiners JJ Jr, Mathieu P, Okafor C, Putt DA, Lash LH. Depletion of cellular glutathione by conditions used for the passaging of adherent cultured cells. Toxicol Lett 2000;115:153-63.
    • (2000) Toxicol Lett , vol.115 , pp. 153-163
    • Reiners Jr., J.J.1    Mathieu, P.2    Okafor, C.3    Putt, D.A.4    Lash, L.H.5
  • 17
    • 0021808951 scopus 로고
    • Free radical damage to cultured porcine aortic endothelial cells and lung fibroblasts: Modulation by culture conditions
    • Bishop CT, Mirza Z, Crapo JD, Freeman BA. Free radical damage to cultured porcine aortic endothelial cells and lung fibroblasts: Modulation by culture conditions. In Vitro Cell Dev Biol Anim 1985;21:229-36.
    • (1985) Vitro Cell Dev Biol Anim , vol.21 , pp. 229-236
    • Bishop, C.T.1    Mirza, Z.2    Crapo, J.D.3    Freeman, B.A.4
  • 18
    • 0028000990 scopus 로고
    • Individual, culture-specific alterations in the human endothelial glutathione system: Relationships to oxidant toxicity
    • Tu B, Wallin A, Moldéus P, Cotgreave IA. Individual, culture-specific alterations in the human endothelial glutathione system: Relationships to oxidant toxicity. Pharmacol Toxicol 1994;75:82-90.
    • (1994) Pharmacol Toxicol , vol.75 , pp. 82-90
    • Tu, B.1    Wallin, A.2    Moldéus, P.3    Cotgreave, I.A.4
  • 20
    • 0033993450 scopus 로고    scopus 로고
    • The p53 tumor suppressor protein does not regulate expression of its own inhibitor, MDM2, except under conditions of stress
    • Mendrysa SM, Perry ME. The p53 tumor suppressor protein does not regulate expression of its own inhibitor, MDM2, except under conditions of stress. Mol Cell Biol 2000;20:2023-30.
    • (2000) Mol Cell Biol , vol.20 , pp. 2023-2030
    • Mendrysa, S.M.1    Perry, M.E.2
  • 21
    • 77951751797 scopus 로고    scopus 로고
    • P53 functions and cell lines: Have we learned the lessons from the past?
    • Millau JF, Mai S, Bastien N, Douin R. p53 functions and cell lines: Have we learned the lessons from the past? Bioessays 2010;32:392-400.
    • (2010) Bioessays , vol.32 , pp. 392-400
    • Millau, J.F.1    Mai, S.2    Bastien, N.3    Douin, R.4
  • 22
    • 77955121151 scopus 로고    scopus 로고
    • Microglial activation and neuroinflammation in Alzheimer's disease: A critical examination of recent history
    • Streit WJ. Microglial activation and neuroinflammation in Alzheimer's disease: A critical examination of recent history. Front Aging Neurosci 2010;2:22.
    • (2010) Front Aging Neurosci , vol.2 , pp. 22
    • Streit, W.J.1
  • 25
    • 0024512739 scopus 로고
    • Hypoxia, reactive oxygen and cell injury
    • de Groot H, Littauer A. Hypoxia, reactive oxygen and cell injury. Free Radic Biol Med 1989;6:541-51.
    • (1989) Free Radic Biol Med , vol.6 , pp. 541-551
    • De Groot, H.1    Littauer, A.2
  • 26
    • 0021279087 scopus 로고
    • Hyperoxia enhances lung and liver nuclear superoxide generation
    • Yusa T, Crapo JD, Freeman BA. Hyperoxia enhances lung and liver nuclear superoxide generation. Biochim Biophys Acta 1984;798:167-74.
    • (1984) Biochim Biophys Acta , vol.798 , pp. 167-174
    • Yusa, T.1    Crapo, J.D.2    Freeman, B.A.3
  • 27
    • 0020397137 scopus 로고
    • The effect of hyperoxia on superoxide production by lung submitochondrial particles
    • Turrens JF, Freeman BA, Levitt JG, Crapo JD. The effect of hyperoxia on superoxide production by lung submitochondrial particles. Arch Biochem Biophys 1982;217:401-10.
    • (1982) Arch Biochem Biophys , vol.217 , pp. 401-410
    • Turrens, J.F.1    Freeman, B.A.2    Levitt, J.G.3    Crapo, J.D.4
  • 28
    • 0032694302 scopus 로고    scopus 로고
    • The broad spectrum of responses to oxidants in proliferating cells: A new paradigm for oxidative stress
    • Davies KJ. The broad spectrum of responses to oxidants in proliferating cells: A new paradigm for oxidative stress. IUBMB Life 1999;48:41-7.
    • (1999) IUBMB Life , vol.48 , pp. 41-47
    • Davies, K.J.1
  • 29
    • 78049361603 scopus 로고    scopus 로고
    • H 2 O 2-induced mitochondrial fragmentation in C2C12 myoctes
    • Fan X, Hussien R, Brooks GA. H 2 O 2-induced mitochondrial fragmentation in C2C12 myoctes. Free Radic Biol Med 2010;49:1646-54.
    • (2010) Free Radic Biol Med , vol.49 , pp. 1646-1654
    • Fan, X.1    Hussien, R.2    Brooks, G.A.3
  • 30
    • 0035114576 scopus 로고    scopus 로고
    • Putative telomere-independent mechanisms of replicative aging reflect inadequate growth conditions
    • Ramirez RD, Morales CP, Herbert BS, Rohde JM, Passons C, Shay JW, et al. Putative telomere-independent mechanisms of replicative aging reflect inadequate growth conditions. Genes Dev 2001;15:398-403.
    • (2001) Genes Dev , vol.15 , pp. 398-403
    • Ramirez, R.D.1    Morales, C.P.2    Herbert, B.S.3    Rohde, J.M.4    Passons, C.5    Shay, J.W.6
  • 31
    • 0036629255 scopus 로고    scopus 로고
    • Oxidative stress shortens telomeres
    • von Zglinicki T. Oxidative stress shortens telomeres. Trends Biochem Sci 2002;27:339-44.
    • (2002) Trends Biochem Sci , vol.27 , pp. 339-344
    • Von Zglinicki, T.1
  • 32
    • 84862666196 scopus 로고    scopus 로고
    • Impact of medium volume and oxygen concentration in the incubator on pericellular oxygen concentration and differentiation of murine chondrogenic cell culture
    • Oze H, Hirao M, Ebina K, Shi K, Kawato Y, Kaneshiro S, et al. Impact of medium volume and oxygen concentration in the incubator on pericellular oxygen concentration and differentiation of murine chondrogenic cell culture. In Vitro Cell Dev Biol Anim 2012;48:123-30.
    • (2012) Vitro Cell Dev Biol Anim , vol.48 , pp. 123-130
    • Oze, H.1    Hirao, M.2    Ebina, K.3    Shi, K.4    Kawato, Y.5    Kaneshiro, S.6
  • 33
    • 80051926771 scopus 로고    scopus 로고
    • Normal atmospheric oxygen tension and the use of antioxidants improve hepatocyte spheroid viability and function
    • Lillegard JB, Fisher JE, Nedredal G, Luebke-Wheeler J, Bao J, Wang W, et al. Normal atmospheric oxygen tension and the use of antioxidants improve hepatocyte spheroid viability and function. J Cell Physiol 2011;22:2987-96.
    • (2011) J Cell Physiol , vol.22 , pp. 2987-2996
    • Lillegard, J.B.1    Fisher, J.E.2    Nedredal, G.3    Luebke-Wheeler, J.4    Bao, J.5    Wang, W.6
  • 34
    • 77951526231 scopus 로고    scopus 로고
    • Protection of cells in physiological oxygen tensions against DNA damage-induced apoptosis
    • Carrera S, de Verdier PJ, Khan Z, Zhao B, Mahale A, Bowman KJ, et al. Protection of cells in physiological oxygen tensions against DNA damage-induced apoptosis. J Biol Chem 2010;285:13658-65.
    • (2010) J Biol Chem , vol.285 , pp. 13658-13665
    • Carrera, S.1    De Verdier, P.J.2    Khan, Z.3    Zhao, B.4    Mahale, A.5    Bowman, K.J.6
  • 36
    • 84859247838 scopus 로고    scopus 로고
    • Does hyperoxia selection cause adaptive alterations of mitochondrial electron transfer chain activity leading to a reduction of superoxide production?
    • Zhao HW, Ali SS, Haddad GG. Does hyperoxia selection cause adaptive alterations of mitochondrial electron transfer chain activity leading to a reduction of superoxide production? Antioxid Redox Signal 2012;16:1071-6.
    • (2012) Antioxid Redox Signal , vol.16 , pp. 1071-1076
    • Zhao, H.W.1    Ali, S.S.2    Haddad, G.G.3
  • 37
    • 0028528590 scopus 로고
    • Low mitochondrial free radical production per unit O 2 consumption can explain the simultaneous presence of high longevity and high aerobic metabolic rate in birds
    • Barja G, Cadenas S, Rojas C, Pérez-Campo R, López-Torres M. Low mitochondrial free radical production per unit O 2 consumption can explain the simultaneous presence of high longevity and high aerobic metabolic rate in birds. Free Radic Res 1994;21:317-27.
    • (1994) Free Radic Res , vol.21 , pp. 317-327
    • Barja, G.1    Cadenas, S.2    Rojas, C.3    Pérez-Campo, R.4    López-Torres, M.5
  • 38
    • 0024454931 scopus 로고
    • Chromosomal instability and progressive loss of chromosomes in HeLa cells during adaptation to hyperoxic growth conditions
    • Gille JJ, Joenje H. Chromosomal instability and progressive loss of chromosomes in HeLa cells during adaptation to hyperoxic growth conditions. Mutat Res 1989;219:225-30.
    • (1989) Mutat Res , vol.219 , pp. 225-230
    • Gille, J.J.1    Joenje, H.2
  • 39
    • 34447093423 scopus 로고    scopus 로고
    • Superoxide anion: Oncogenic reactive oxygen species
    • Pervaiz S, Clement MV. Superoxide anion: Oncogenic reactive oxygen species. Int J Biochem Cell Biol 2007;39:1297-304.
    • (2007) Int J Biochem Cell Biol , vol.39 , pp. 1297-1304
    • Pervaiz, S.1    Clement, M.V.2
  • 40
    • 0035932395 scopus 로고    scopus 로고
    • Elevated superoxide production by active H-ras enhances human lung WI-38VA-13 cell proliferation, migration and resistance to TNF-alpha
    • Liu R, Li B, Qiu M. Elevated superoxide production by active H-ras enhances human lung WI-38VA-13 cell proliferation, migration and resistance to TNF-alpha. Oncogene 2001;20:1486-96.
    • (2001) Oncogene , vol.20 , pp. 1486-1496
    • Liu, R.1    Li, B.2    Qiu, M.3
  • 41
    • 0029854544 scopus 로고    scopus 로고
    • Free radicals, proteins and DNA: Oxidative damage versus redox regulation
    • Halliwell B. Free radicals, proteins and DNA: Oxidative damage versus redox regulation. Biochem Soc Trans 1996;24:1023-7.
    • (1996) Biochem Soc Trans , vol.24 , pp. 1023-1027
    • Halliwell, B.1
  • 42
    • 36749010860 scopus 로고    scopus 로고
    • Biochemistry of oxidative stress
    • Halliwell B. Biochemistry of oxidative stress. Biochem Soc Trans 2007;35:1147-9.
    • (2007) Biochem Soc Trans , vol.35 , pp. 1147-1149
    • Halliwell, B.1
  • 43
    • 80052032471 scopus 로고    scopus 로고
    • Metabolic flux analysis of CHO cells at growth and non-growth phases using isotopic tracers and mass spectrometry
    • Ahn WS, Antoniewicz MR. Metabolic flux analysis of CHO cells at growth and non-growth phases using isotopic tracers and mass spectrometry. Metab Eng 2011;13:598-609.
    • (2011) Metab Eng , vol.13 , pp. 598-609
    • Ahn, W.S.1    Antoniewicz, M.R.2
  • 45
    • 84855793669 scopus 로고    scopus 로고
    • The effects of oxaloacetate on hydrogen peroxide generation from ascorbate and epigallocatechin gallate in cell culture media: Potential for altering cell metabolism
    • Long LH, Halliwell B. The effects of oxaloacetate on hydrogen peroxide generation from ascorbate and epigallocatechin gallate in cell culture media: Potential for altering cell metabolism. Biochem Biophys Res Commun 2012;471:446-50.
    • (2012) Biochem Biophys Res Commun , vol.471 , pp. 446-450
    • Long, L.H.1    Halliwell, B.2
  • 46
    • 69949112741 scopus 로고    scopus 로고
    • Artefacts in cell culture: Pyruvate as a scavenger of hydrogen peroxide generated by ascorbate or epigallocatechin gallate in cell culture media
    • Long LH, Halliwell B. Artefacts in cell culture: Pyruvate as a scavenger of hydrogen peroxide generated by ascorbate or epigallocatechin gallate in cell culture media. Biochem Biophys Res Commun 2009;388:700-4.
    • (2009) Biochem Biophys Res Commun , vol.388 , pp. 700-704
    • Long, L.H.1    Halliwell, B.2
  • 47
    • 79952190949 scopus 로고    scopus 로고
    • Artefacts in cell culture: α-ketoglutarate can scavenge hydrogen peroxide generated by ascorbate and epigallocatechin gallate in cell culture media
    • Long LH, Halliwell B. Artefacts in cell culture: α-ketoglutarate can scavenge hydrogen peroxide generated by ascorbate and epigallocatechin gallate in cell culture media. Biochem Biophys Res Commun 2011;406:20-4.
    • (2011) Biochem Biophys Res Commun , vol.406 , pp. 20-24
    • Long, L.H.1    Halliwell, B.2
  • 48
    • 0034036570 scopus 로고    scopus 로고
    • Pyruvate secreted by human lymphoid cell lines protects cells from hydrogen peroxide mediated cell death
    • Miwa H, Fujii J, Kanno H, Taniguchi N, Aozasa K. Pyruvate secreted by human lymphoid cell lines protects cells from hydrogen peroxide mediated cell death. Free Radic Res 2000;33:45-56.
    • (2000) Free Radic Res , vol.33 , pp. 45-56
    • Miwa, H.1    Fujii, J.2    Kanno, H.3    Taniguchi, N.4    Aozasa, K.5
  • 49
    • 67449091665 scopus 로고    scopus 로고
    • Choice of DMEM, formulated with or without pyruvate, plays an important role in assessing the in vitro cytotoxicity of oxidants and prooxidant nutraceuticals
    • Babich H, Liebling EG, Burger RF, Zuckerbraun HL, Schuck AG. Choice of DMEM, formulated with or without pyruvate, plays an important role in assessing the in vitro cytotoxicity of oxidants and prooxidant nutraceuticals. In Vitro Cell Dev Biol Anim 2009;45:226-33.
    • (2009) Vitro Cell Dev Biol Anim , vol.45 , pp. 226-233
    • Babich, H.1    Liebling, E.G.2    Burger, R.F.3    Zuckerbraun, H.L.4    Schuck, A.G.5
  • 50
    • 78349297565 scopus 로고    scopus 로고
    • Oxidative stress and diabetic complications
    • Giacco F, Brownlee M. Oxidative stress and diabetic complications. Circ Res 2010;107:1058-70.
    • (2010) Circ Res , vol.107 , pp. 1058-1070
    • Giacco, F.1    Brownlee, M.2
  • 51
    • 77954822251 scopus 로고    scopus 로고
    • Mitochondrial reactive oxygen species mediate cardiomyocyte formation from embryonic stem cells in high glucose
    • Crespo FL, Sobrado VR, Gomez L, Cervera AM, McCreath KJ. Mitochondrial reactive oxygen species mediate cardiomyocyte formation from embryonic stem cells in high glucose. Stem Cells 2010;28:1132-42.
    • (2010) Stem Cells , vol.28 , pp. 1132-1142
    • Crespo, F.L.1    Sobrado, V.R.2    Gomez, L.3    Cervera, A.M.4    McCreath, K.J.5
  • 52
    • 0029741901 scopus 로고    scopus 로고
    • Conventional cell culture media do not adequately supply cells with antioxidants and thus facilitate peroxide-induced genotoxicity
    • Leist M, Raab B, Maurer S, Rösick U, Brigelius-Flohé. Conventional cell culture media do not adequately supply cells with antioxidants and thus facilitate peroxide-induced genotoxicity. Free Radic Biol Med 1996;21:297-306.
    • (1996) Free Radic Biol Med , vol.21 , pp. 297-306
    • Leist, M.1    Raab, B.2    Maurer, S.3    Rösick, U.4    Brigelius-Flohé5
  • 53
    • 0036634864 scopus 로고    scopus 로고
    • Vitamin C matters: Increased oxidative stress in culture human aortic endothelial cells without supplemental ascorbic acid
    • Smith AR, Visioli F, Hagen TM. Vitamin C matters: Increased oxidative stress in culture human aortic endothelial cells without supplemental ascorbic acid. FASEB J 2002;16:1102-4.
    • (2002) FASEB J , vol.16 , pp. 1102-1104
    • Smith, A.R.1    Visioli, F.2    Hagen, T.M.3
  • 54
    • 0344157897 scopus 로고    scopus 로고
    • Selenium deficiency in tissue culture: Implications for oxidative metabolism
    • Baker RD Jr, Baker SS, Rao R. Selenium deficiency in tissue culture: Implications for oxidative metabolism. J Pediatr Gastroenterol Nutr 1998;27:387-92.
    • (1998) J Pediatr Gastroenterol Nutr , vol.27 , pp. 387-392
    • Baker Jr., R.D.1    Baker, S.S.2    Rao, R.3
  • 55
    • 79957731140 scopus 로고    scopus 로고
    • The selenium content of cell culture serum influences redox-regulated gene expression
    • Karlenius TC, Shah F, Yu WC, Hawkes HK, Tinggi U, Clarke FM, et al. The selenium content of cell culture serum influences redox-regulated gene expression. Biotechniques 2011;50:295-301.
    • (2011) Biotechniques , vol.50 , pp. 295-301
    • Karlenius, T.C.1    Shah, F.2    Yu, W.C.3    Hawkes, H.K.4    Tinggi, U.5    Clarke, F.M.6
  • 56
    • 84856940017 scopus 로고    scopus 로고
    • Peroxiredoxin functions as a peroxidase and a regulator and sensor of local peroxide
    • Rhee SG, Woo HA, Kil IS, Bae SH. Peroxiredoxin functions as a peroxidase and a regulator and sensor of local peroxide. J Biol Chem 2012;287:4403-10.
    • (2012) J Biol Chem , vol.287 , pp. 4403-4410
    • Rhee, S.G.1    Woo, H.A.2    Kil, I.S.3    Bae, S.H.4
  • 57
    • 0029957584 scopus 로고    scopus 로고
    • Catalytic metal ions and the loss of reduced glutathione from University of Wisconsin preservation solution
    • Evans PJ, Tredger JM, Dunne JB, Halliwell B. Catalytic metal ions and the loss of reduced glutathione from University of Wisconsin preservation solution. Transplantation 1996;62:1046-9.
    • (1996) Transplantation , vol.62 , pp. 1046-1049
    • Evans, P.J.1    Tredger, J.M.2    Dunne, J.B.3    Halliwell, B.4
  • 58
    • 34748921067 scopus 로고    scopus 로고
    • Redistribution of metal ions to control low density lipoprotein oxidation in Ham's F10 medium
    • Firth CA, Gieseg SP. Redistribution of metal ions to control low density lipoprotein oxidation in Ham's F10 medium. Free Radic Res 2007;41:1109-15.
    • (2007) Free Radic Res , vol.41 , pp. 1109-1115
    • Firth, C.A.1    Gieseg, S.P.2
  • 59
    • 0023144940 scopus 로고
    • Superoxide-dependent and ascorbate-dependent formation of hydroxyl radicals from hydrogen peroxide in the presence of iron, Are lactoferrin and transferrin promoters of hydroxyl-radical generation?
    • Aruoma OI, Halliwell B. Superoxide-dependent and ascorbate-dependent formation of hydroxyl radicals from hydrogen peroxide in the presence of iron. Are lactoferrin and transferrin promoters of hydroxyl-radical generation? Biochem J 1987;241:273-8.
    • (1987) Biochem J , vol.241 , pp. 273-278
    • Aruoma, O.I.1    Halliwell, B.2
  • 60
    • 0034709554 scopus 로고    scopus 로고
    • Artifacts in cell culture: Rapid generation of hydrogen peroxide on addition of (-)-epigallocatechin, (-)-epigallocatechin gallate, (+)-catechin and quercetin to commonly used cell culture media
    • Long LH, Clement MV, Halliwell B. Artifacts in cell culture: Rapid generation of hydrogen peroxide on addition of (-)-epigallocatechin, (-)-epigallocatechin gallate, (+)-catechin and quercetin to commonly used cell culture media. Biochem Biophys Res Commun 2000;273:50-3.
    • (2000) Biochem Biophys Res Commun , vol.273 , pp. 50-53
    • Long, L.H.1    Clement, M.V.2    Halliwell, B.3
  • 61
    • 0034810075 scopus 로고    scopus 로고
    • Oxidation and generation of hydrogen peroxide by thiol compounds in commonly used cell culture media
    • Hua Long L, Halliwell B. Oxidation and generation of hydrogen peroxide by thiol compounds in commonly used cell culture media. Biochem Biophys Res Commun 2000;286:991-4.
    • (2000) Biochem Biophys Res Commun , vol.286 , pp. 991-994
    • Hua Long, L.1    Halliwell, B.2
  • 62
    • 0035087490 scopus 로고    scopus 로고
    • The in vitro cytotoxicity of ascorbate depends on the culture medium used to perform the assay and involves hydrogen peroxide
    • Clement MV, Ramalingam J, Long LH, Halliwell B. The in vitro cytotoxicity of ascorbate depends on the culture medium used to perform the assay and involves hydrogen peroxide. Antioxid Redox Signal 2001;3:157-63.
    • (2001) Antioxid Redox Signal , vol.3 , pp. 157-163
    • Clement, M.V.1    Ramalingam, J.2    Long, L.H.3    Halliwell, B.4
  • 63
    • 48349140474 scopus 로고    scopus 로고
    • Are polyphenols antioxidants or pro-oxidants? What do we learn from cell culture and in vivo studies?
    • Halliwell B. Are polyphenols antioxidants or pro-oxidants? What do we learn from cell culture and in vivo studies? Arch Biochem Biophys 2008;476:107-12.
    • (2008) Arch Biochem Biophys , vol.476 , pp. 107-112
    • Halliwell, B.1
  • 64
    • 35448989644 scopus 로고    scopus 로고
    • Different cytotoxic and clastogenic effects of epigallocatechin gallate in various cell-culture media due to variable rates of its oxidation in the culture medium
    • Long LH, Kirkland D, Whitwell J, Halliwell B. Different cytotoxic and clastogenic effects of epigallocatechin gallate in various cell-culture media due to variable rates of its oxidation in the culture medium. Mutat Res 2007;634:177-83.
    • (2007) Mutat Res , vol.634 , pp. 177-183
    • Long, L.H.1    Kirkland, D.2    Whitwell, J.3    Halliwell, B.4
  • 65
    • 0036589809 scopus 로고    scopus 로고
    • Hydrogen peroxide generation in caco-2 cell culture medium by addition of phenolic compounds: Effect of ascorbic acid
    • Roques SC, Landrault N, Teissèdre PL, Laurent C, Besançon P, Rouane JM, et al. Hydrogen peroxide generation in caco-2 cell culture medium by addition of phenolic compounds: Effect of ascorbic acid. Free Radic Res 2002;36:593-9.
    • (2002) Free Radic Res , vol.36 , pp. 593-599
    • Roques, S.C.1    Landrault, N.2    Teissèdre, P.L.3    Laurent, C.4    Besançon, P.5    Rouane, J.M.6
  • 66
    • 34948835711 scopus 로고    scopus 로고
    • Limited stability in cell culture medium and hydrogen peroxide formation affect the growth inhibitory properties of delphinidin and its degradation product gallic acid
    • Kern M, Fridrich D, Reichert J, Skrbek S, Nussher A, Hofem S, et al. Limited stability in cell culture medium and hydrogen peroxide formation affect the growth inhibitory properties of delphinidin and its degradation product gallic acid. Mol Nutr Food Res 2007;51:1163-72.
    • (2007) Mol Nutr Food Res , vol.51 , pp. 1163-1172
    • Kern, M.1    Fridrich, D.2    Reichert, J.3    Skrbek, S.4    Nussher, A.5    Hofem, S.6
  • 67
    • 81855207254 scopus 로고    scopus 로고
    • Polyphenols activate Nrf2 in astrocytes via H 2 O 2, semiquinones, and quinones
    • Erlank H, Elmann A, Kohen R, Kanner J. Polyphenols activate Nrf2 in astrocytes via H 2 O 2, semiquinones, and quinones. Free Radic Biol Med 2011;51:2319-27.
    • (2011) Free Radic Biol Med , vol.51 , pp. 2319-2327
    • Erlank, H.1    Elmann, A.2    Kohen, R.3    Kanner, J.4
  • 68
    • 0026033255 scopus 로고
    • Factors influencing survival of mammalian cells exposed to hypothermia. V. Effects of hepes, free radicals, and H 2 O 2 under light and dark conditions
    • Zieger MA, Glofcheski DJ, Lepock JR, Kruuv J. Factors influencing survival of mammalian cells exposed to hypothermia. V. Effects of hepes, free radicals, and H 2 O 2 under light and dark conditions. Cryobiology 1991;28:8-17.
    • (1991) Cryobiology , vol.28 , pp. 8-17
    • Zieger, M.A.1    Glofcheski, D.J.2    Lepock, J.R.3    Kruuv, J.4
  • 69
    • 0018146110 scopus 로고
    • Identification of hydrogen peroxide as a photoproduct toxic to human cells in tissue-culture medium irradiated with daylight fluorescent light
    • Wang RJ, Nixon BR. Identification of hydrogen peroxide as a photoproduct toxic to human cells in tissue-culture medium irradiated with daylight fluorescent light. In Vitro 1978;14:715-22.
    • (1978) Vitro , vol.14 , pp. 715-722
    • Wang, R.J.1    Nixon, B.R.2
  • 70
    • 0027155884 scopus 로고
    • Autocrine production of extracellular catalase prevents apoptosis of the human CEM T-cell line in serum-free medium
    • Sandstrom PA, Buttke TM. Autocrine production of extracellular catalase prevents apoptosis of the human CEM T-cell line in serum-free medium. Proc Natl Acad Sci USA 1993;90:4708-12.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 4708-4712
    • Sandstrom, P.A.1    Buttke, T.M.2
  • 71
    • 0034827220 scopus 로고    scopus 로고
    • Catalase contents in cells determine sensitivity to the apoptosis inducer gallic acid
    • Isuzugama K, Inoue M, Ogihara Y. Catalase contents in cells determine sensitivity to the apoptosis inducer gallic acid. Biol Pharm Bull 2001;24:1022-6.
    • (2001) Biol Pharm Bull , vol.24 , pp. 1022-1026
    • Isuzugama, K.1    Inoue, M.2    Ogihara, Y.3
  • 72
    • 0142125716 scopus 로고    scopus 로고
    • Factors affecting the ascorbate-and phenolic-dependent generation of hydrogen peroxide in Dulbecco's modified Eagles medium
    • Wee LM, Long LH, Whiteman M, Halliwell B. Factors affecting the ascorbate-and phenolic-dependent generation of hydrogen peroxide in Dulbecco's modified Eagles medium. Free Radic Res 2003;37:1123-30.
    • (2003) Free Radic Res , vol.37 , pp. 1123-1130
    • Wee, L.M.1    Long, L.H.2    Whiteman, M.3    Halliwell, B.4
  • 73
    • 18344367063 scopus 로고    scopus 로고
    • Extracellular superoxide dismutase and glomerular mesangial cells: Its production and regulation
    • Yamada H, Adachi T, Fukatsu A, Misao S, Yamada Y, Aoki T, et al. Extracellular superoxide dismutase and glomerular mesangial cells: Its production and regulation. FEBS Lett 2002;519:77-81.
    • (2002) FEBS Lett , vol.519 , pp. 77-81
    • Yamada, H.1    Adachi, T.2    Fukatsu, A.3    Misao, S.4    Yamada, Y.5    Aoki, T.6
  • 74
    • 77956319013 scopus 로고    scopus 로고
    • Mesenchymal stem cell-secreted superoxide dismutase promotes cerebellar neuronal survival
    • Kemp K, Hares K, Mallam E, Heesom KJ, Scolding N, Wilkins A. Mesenchymal stem cell-secreted superoxide dismutase promotes cerebellar neuronal survival. J Neurochem 2010;114:1569-80.
    • (2010) J Neurochem , vol.114 , pp. 1569-1580
    • Kemp, K.1    Hares, K.2    Mallam, E.3    Heesom, K.J.4    Scolding, N.5    Wilkins, A.6
  • 75
    • 77956176217 scopus 로고    scopus 로고
    • Instability of, and generation of hydrogen peroxide by, phenolic compounds in cell culture media
    • Long LH, Hoi A, Halliwell B. Instability of, and generation of hydrogen peroxide by, phenolic compounds in cell culture media. Arch Biochem Biophys 2010;501:162-9.
    • (2010) Arch Biochem Biophys , vol.501 , pp. 162-169
    • Long, L.H.1    Hoi, A.2    Halliwell, B.3
  • 76
    • 67651020758 scopus 로고    scopus 로고
    • Structure activity relationship of carotenoid derivatives in activation of the electrophile/antioxidant response element transcription system
    • Linnewiel K, Ernst H, Caris-Veyrat C, Ben-Dor A, Kampf A, Salman H. Structure activity relationship of carotenoid derivatives in activation of the electrophile/antioxidant response element transcription system. Free Radic Biol Med 2009;47:659-67.
    • (2009) Free Radic Biol Med , vol.47 , pp. 659-667
    • Linnewiel, K.1    Ernst, H.2    Caris-Veyrat, C.3    Ben-Dor, A.4    Kampf, A.5    Salman, H.6
  • 77
    • 0036313035 scopus 로고    scopus 로고
    • The cytotoxicity of dopamine may be an artefact of cell culture
    • Clement MV, Long LH, Ramalingam J, Halliwell B. The cytotoxicity of dopamine may be an artefact of cell culture. J Neurochem 2002;81:414-21.
    • (2002) J Neurochem , vol.81 , pp. 414-421
    • Clement, M.V.1    Long, L.H.2    Ramalingam, J.3    Halliwell, B.4
  • 78
    • 80053461950 scopus 로고    scopus 로고
    • Comment on hydroxytyrosol induces proliferation and cytoprotection against oxidative injury in vascular endothelial cells: Role of Nrf2 activation and HO-1 induction
    • Schaffer S, Halliwell B. Comment on hydroxytyrosol induces proliferation and cytoprotection against oxidative injury in vascular endothelial cells: Role of Nrf2 activation and HO-1 induction. J Agric Food Chem 2011;59:10770-1.
    • (2011) J Agric Food Chem , vol.59 , pp. 10770-10771
    • Schaffer, S.1    Halliwell, B.2
  • 79
    • 77950099272 scopus 로고    scopus 로고
    • Medicinal plants and antioxidants: What do we learn from cell culture and Caenorhabditis elegans studies?
    • Tang SY, Halliwell B. Medicinal plants and antioxidants: What do we learn from cell culture and Caenorhabditis elegans studies? Biochem Biophys Res Commun 2010;394:1-5.
    • (2010) Biochem Biophys Res Commun , vol.394 , pp. 1-5
    • Tang, S.Y.1    Halliwell, B.2
  • 80
    • 33746374439 scopus 로고    scopus 로고
    • Effect of Ganoderma lucidum on human DNA is dose dependent and mediated by hydrogen peroxide
    • Wachtel-Galor S, Choi SW, Benzie IF. Effect of Ganoderma lucidum on human DNA is dose dependent and mediated by hydrogen peroxide. Redox Rep 2005;10:145-9.
    • (2005) Redox Rep , vol.10 , pp. 145-149
    • Wachtel-Galor, S.1    Choi, S.W.2    Benzie, I.F.3
  • 81
    • 33947285429 scopus 로고    scopus 로고
    • Effects of garcinol and its derivatives on intestinal cell growth: Inhibitory effects and autoxidation-dependent growth-stimulatory effects
    • Hong J, Kwon SJ, Sang S, Ju J, Zhou JN, Ho CT, et al. Effects of garcinol and its derivatives on intestinal cell growth: Inhibitory effects and autoxidation-dependent growth-stimulatory effects. Free Radic Biol Med 2007;42:1211-21.
    • (2007) Free Radic Biol Med , vol.42 , pp. 1211-1221
    • Hong, J.1    Kwon, S.J.2    Sang, S.3    Ju, J.4    Zhou, J.N.5    Ho, C.T.6
  • 82
    • 0034585955 scopus 로고    scopus 로고
    • Reactive oxygen species are formed in cell culture media
    • Grzelak A, Rychlik B, Bartosz G. Reactive oxygen species are formed in cell culture media. Acta Biochim Pol 2000;47:1197-8.
    • (2000) Acta Biochim Pol , vol.47 , pp. 1197-1198
    • Grzelak, A.1    Rychlik, B.2    Bartosz, G.3
  • 83
    • 0034056779 scopus 로고    scopus 로고
    • Coffee drinking increases levels of urinary hydrogen peroxide detected in healthy human volunteers
    • Long LH, Halliwell B. Coffee drinking increases levels of urinary hydrogen peroxide detected in healthy human volunteers. Free Radic Res 2000;32:463-7.
    • (2000) Free Radic Res , vol.32 , pp. 463-467
    • Long, L.H.1    Halliwell, B.2


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