메뉴 건너뛰기




Volumn 23, Issue 20, 2003, Pages 7315-7328

Akt-directed glucose metabolism can prevent Bax conformation change and promote growth factor-independent survival

Author keywords

[No Author keywords available]

Indexed keywords

6 PHOSPHOFRUCTOKINASE; GLUCOSE; GLUCOSE TRANSPORTER 1; GROWTH FACTOR; HEXOKINASE; PENTOSE PHOSPHATE; PROTEIN BAX; PROTEIN KINASE B; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;

EID: 0141863388     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.23.20.7315-7328.2003     Document Type: Article
Times cited : (489)

References (68)
  • 1
    • 0037163688 scopus 로고    scopus 로고
    • Evaluation of 2-deoxy-D-glucose as a chemotherapeutic agent: Mechanism of cell death
    • Aft, R. L., F. W. Zhang, and D. Gius. 2002. Evaluation of 2-deoxy-D-glucose as a chemotherapeutic agent: mechanism of cell death. Br. J. Cancer 87:805-812.
    • (2002) Br. J. Cancer , vol.87 , pp. 805-812
    • Aft, R.L.1    Zhang, F.W.2    Gius, D.3
  • 2
    • 0031127305 scopus 로고    scopus 로고
    • Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Bα
    • Alessi, D. R., S. R. James, C. P. Downes, A. B. Holmes, P. R. Gaffney, C. B. Reese, and P. Cohen. 1997. Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Bα. Curr. Biol. 7:261-269.
    • (1997) Curr. Biol. , vol.7 , pp. 261-269
    • Alessi, D.R.1    James, S.R.2    Downes, C.P.3    Holmes, A.B.4    Gaffney, P.R.5    Reese, C.B.6    Cohen, P.7
  • 3
    • 0031783046 scopus 로고    scopus 로고
    • ELAV protein HuA (HuR) can redistribute between nucleus and cytoplasm and is upregulated during serum stimulation and T cell activation
    • Atasoy, U., J. Watson, D. Patel, and J. D. Keene. 1998. ELAV protein HuA (HuR) can redistribute between nucleus and cytoplasm and is upregulated during serum stimulation and T cell activation. J. Cell Sci. 111:3145-3156.
    • (1998) J. Cell Sci. , vol.111 , pp. 3145-3156
    • Atasoy, U.1    Watson, J.2    Patel, D.3    Keene, J.D.4
  • 4
    • 0029550551 scopus 로고
    • Trafficking of glucose transporters-signals and mechanisms
    • Baldwin, S. A., L. F. Barros, and M. Griffiths. 1995. Trafficking of glucose transporters-signals and mechanisms. Biosci. Rep. 15:419-426.
    • (1995) Biosci. Rep. , vol.15 , pp. 419-426
    • Baldwin, S.A.1    Barros, L.F.2    Griffiths, M.3
  • 6
    • 0026095665 scopus 로고
    • A retroviral oncogene, akt, encoding a serine-threonine kinase containing an SH2-like region
    • Bellacosa, A., J. R. Testa, S. P. Staal, and P. N. Tsichlis. 1991. A retroviral oncogene, akt, encoding a serine-threonine kinase containing an SH2-like region. Science 254:274-277.
    • (1991) Science , vol.254 , pp. 274-277
    • Bellacosa, A.1    Testa, J.R.2    Staal, S.P.3    Tsichlis, P.N.4
  • 8
    • 0037192787 scopus 로고    scopus 로고
    • Increased hexokinase activity, of either ectopic or endogenous origin, protects renal epithelial cells against acute oxidant-induced cell death
    • Bryson, J. M., P. E. Coy, K. Gottlob, N. Hay, and R. B. Robey. 2002. Increased hexokinase activity, of either ectopic or endogenous origin, protects renal epithelial cells against acute oxidant-induced cell death. J. Biol. Chem. 277:11392-11400.
    • (2002) J. Biol. Chem. , vol.277 , pp. 11392-11400
    • Bryson, J.M.1    Coy, P.E.2    Gottlob, K.3    Hay, N.4    Robey, R.B.5
  • 10
    • 0026006501 scopus 로고
    • Molecular cloning and characterisation of a novel protein-serine kinase related to the cAMP-dependent and protein kinase C families
    • Coffer, P. J., and J. R. Woodgett. 1991. Molecular cloning and characterisation of a novel protein-serine kinase related to the cAMP-dependent and protein kinase C families. Eur. J. Biochem. 201:475-481.
    • (1991) Eur. J. Biochem. , vol.201 , pp. 475-481
    • Coffer, P.J.1    Woodgett, J.R.2
  • 11
    • 0033593316 scopus 로고    scopus 로고
    • Size control in animal development
    • Conlon, I., and M. Raff. 1999. Size control in animal development. Cell 96:235-244.
    • (1999) Cell , vol.96 , pp. 235-244
    • Conlon, I.1    Raff, M.2
  • 12
    • 0027485950 scopus 로고
    • Temporal analysis of events associated with programmed cell death (apoptosis) of sympathetic neurons deprived of nerve growth factor
    • Deckwerth, T. L., and E. M. J. Johnson. 1993. Temporal analysis of events associated with programmed cell death (apoptosis) of sympathetic neurons deprived of nerve growth factor. J. Cell Biol. 123:1207-1222.
    • (1993) J. Cell Biol. , vol.123 , pp. 1207-1222
    • Deckwerth, T.L.1    Johnson, E.M.J.2
  • 13
    • 0030458720 scopus 로고    scopus 로고
    • Genetic and metabolic status of NGF-deprived sympathetic neurons saved by an inhibitor or ICE family proteases
    • Deshmukh, M., J. Vasilakos, T. L. Deckwerth, P. A. Lampe, B. D. Shivers, and E. M. J. Johnson. 1996. Genetic and metabolic status of NGF-deprived sympathetic neurons saved by an inhibitor or ICE family proteases. J. Cell Biol. 135:1341-1354.
    • (1996) J. Cell Biol. , vol.135 , pp. 1341-1354
    • Deshmukh, M.1    Vasilakos, J.2    Deckwerth, T.L.3    Lampe, P.A.4    Shivers, B.D.5    Johnson, E.M.J.6
  • 15
    • 0036320205 scopus 로고    scopus 로고
    • Akt maintains cell size and survival by increasing mTOR-dependent nutrient uptake
    • Edinger, A. L., and C. B. Thompson. 2002. Akt maintains cell size and survival by increasing mTOR-dependent nutrient uptake. Mol. Biol. Cell 13:2276-2288.
    • (2002) Mol. Biol. Cell , vol.13 , pp. 2276-2288
    • Edinger, A.L.1    Thompson, C.B.2
  • 16
    • 0033215390 scopus 로고    scopus 로고
    • Protein kinase B stimulates the translocation of GLUT4 but not GLUT1 or transferrin receptors in 3T3-L1 adipocytes by a pathway involving SNAP-23, synaptobrevin-2, and/or cellubrevin
    • Foran, P. G. P., L. M. Fletcher, P. B. Oatey, N. Mohammed, J. O. Dolly, and J. M. Tavare. 1999. Protein kinase B stimulates the translocation of GLUT4 but not GLUT1 or transferrin receptors in 3T3-L1 adipocytes by a pathway involving SNAP-23, synaptobrevin-2, and/or cellubrevin. J. Biol. Chem. 274:28087-28095.
    • (1999) J. Biol. Chem. , vol.274 , pp. 28087-28095
    • Foran, P.G.P.1    Fletcher, L.M.2    Oatey, P.B.3    Mohammed, N.4    Dolly, J.O.5    Tavare, J.M.6
  • 17
    • 0032494166 scopus 로고    scopus 로고
    • Control of neuronal size homeostasis by trophic factor-mediated coupling of protein degradation to protein synthesis
    • Franklin, J. L., and E. M. Johnson. 1998. Control of neuronal size homeostasis by trophic factor-mediated coupling of protein degradation to protein synthesis. J. Cell Biol. 142:1313-1324.
    • (1998) J. Cell Biol. , vol.142 , pp. 1313-1324
    • Franklin, J.L.1    Johnson, E.M.2
  • 19
    • 0036792001 scopus 로고    scopus 로고
    • Mitochondrial respiratory control is lost during growth factor deprivation
    • Gottlieb, E., S. M. Armour, and C. B. Thompson. 2002. Mitochondrial respiratory control is lost during growth factor deprivation. Proc. Natl. Acad. Sci. USA 99:12801-12806.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 12801-12806
    • Gottlieb, E.1    Armour, S.M.2    Thompson, C.B.3
  • 20
    • 0034983918 scopus 로고    scopus 로고
    • Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase
    • Gottlob, K., N. Majewski, S. Kennedy, E. Kandel, R. B. Robey, and N. Hay. 2001. Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase. Genes Dev. 15:1406-1418.
    • (2001) Genes Dev. , vol.15 , pp. 1406-1418
    • Gottlob, K.1    Majewski, N.2    Kennedy, S.3    Kandel, E.4    Robey, R.B.5    Hay, N.6
  • 21
    • 0032528118 scopus 로고    scopus 로고
    • Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis
    • Gross, A., J. Jockel, M. C. Wei, and S. J. Korsmeyer. 1998. Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis. EMBO J. 17:3878-3885.
    • (1998) EMBO J. , vol.17 , pp. 3878-3885
    • Gross, A.1    Jockel, J.2    Wei, M.C.3    Korsmeyer, S.J.4
  • 22
    • 0034781048 scopus 로고    scopus 로고
    • Iodoacetate protects hippocampal neurons against excitotoxic and oxidative injury: Involvement of heat-shock proteins and Bcl-2
    • Guo, Z., J. Lee, M. Lane, and M. Mattson. 2001. Iodoacetate protects hippocampal neurons against excitotoxic and oxidative injury: involvement of heat-shock proteins and Bcl-2. J. Neurochem. 79:361-370.
    • (2001) J. Neurochem. , vol.79 , pp. 361-370
    • Guo, Z.1    Lee, J.2    Lane, M.3    Mattson, M.4
  • 23
    • 0035896366 scopus 로고    scopus 로고
    • Protein kinase B (PKB/Akt) - A key regulator of glucose transport?
    • Hajduch, E., G. J. Litherland, and H. S. Hundal. 2001. Protein kinase B (PKB/Akt) - a key regulator of glucose transport? FEBS Lett. 492:199-203.
    • (2001) FEBS Lett. , vol.492 , pp. 199-203
    • Hajduch, E.1    Litherland, G.J.2    Hundal, H.S.3
  • 24
    • 0032695529 scopus 로고    scopus 로고
    • A role for protein kinase Bβ/Akt2 in insulin-stimulated GLUT4 translocation in adipocytes
    • Hill, M. M., S. F. Clark, D. F. Tucker, M. J. Birnbaum, D. E. James, and S. L. Macaulay. 1999. A role for protein kinase Bβ/Akt2 in insulin-stimulated GLUT4 translocation in adipocytes. Mol. Cell. Biol. 19:7771-7781.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 7771-7781
    • Hill, M.M.1    Clark, S.F.2    Tucker, D.F.3    Birnbaum, M.J.4    James, D.E.5    Macaulay, S.L.6
  • 25
    • 0025204548 scopus 로고
    • Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death
    • Hockenbery, D., G. Nunez, C. Milliman, R. D. Schreiber, and S. J, Korsmeyer. 1990. Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. Nature 348:334-336.
    • (1990) Nature , vol.348 , pp. 334-336
    • Hockenbery, D.1    Nunez, G.2    Milliman, C.3    Schreiber, R.D.4    Korsmeyer, S.J.5
  • 26
    • 0033032863 scopus 로고    scopus 로고
    • Glucose transporter expression in developing fetal lungs and lung neoplasms
    • Ito, T., Y. Noguchi, N. Udaka, H. Kitamura, and S. Satoh. 1999. Glucose transporter expression in developing fetal lungs and lung neoplasms. Histol. Histopathol. 14:895-904.
    • (1999) Histol. Histopathol. , vol.14 , pp. 895-904
    • Ito, T.1    Noguchi, Y.2    Udaka, N.3    Kitamura, H.4    Satoh, S.5
  • 27
    • 0031038858 scopus 로고    scopus 로고
    • Ectopic expression of Hel-N1, an RNA-binding protein, increases glucose transporter (GLUT1) expression in 3T3-L1 adipocytes
    • Jain, R. G., L. G. Andrews, K. M. McGowan, P. H. Pekala, and J. D. Keene. 1997. Ectopic expression of Hel-N1, an RNA-binding protein, increases glucose transporter (GLUT1) expression in 3T3-L1 adipocytes. Mol. Cell. Biol. 17:954-962.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 954-962
    • Jain, R.G.1    Andrews, L.G.2    McGowan, K.M.3    Pekala, P.H.4    Keene, J.D.5
  • 28
    • 0025882091 scopus 로고
    • Molecular cloning and identification of a serine/theonine protein kinase of the second-messenger subfamily
    • Jones, P. F., T. Jakubowicz, F. J. Pitossi, F. Maurer, and B. A. Hemmings. 1991. Molecular cloning and identification of a serine/theonine protein kinase of the second-messenger subfamily. Proc. Natl. Acad. Sci. USA 88:4171-4175.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 4171-4175
    • Jones, P.F.1    Jakubowicz, T.2    Pitossi, F.J.3    Maurer, F.4    Hemmings, B.A.5
  • 31
    • 0034805635 scopus 로고    scopus 로고
    • Detection of aquaporin-2 in the plasma membranes of oocytes: A novel isolation method with improved yield and purity
    • Kamsteeg, E.-J., and P. M. T. Deen. 2001. Detection of aquaporin-2 in the plasma membranes of oocytes: a novel isolation method with improved yield and purity. Biochem. Biophys. Res. Commun. 282:683-690.
    • (2001) Biochem. Biophys. Res. Commun. , vol.282 , pp. 683-690
    • Kamsteeg, E.-J.1    Deen, P.M.T.2
  • 32
    • 0033604585 scopus 로고    scopus 로고
    • The regulation and activities of the multi-functional serine/threonine kinase Akt/PKB
    • Kandel, E. S., and N. Hay. 1999. The regulation and activities of the multi-functional serine/threonine kinase Akt/PKB. Exp. Cell Res. 253:210-229.
    • (1999) Exp. Cell Res. , vol.253 , pp. 210-229
    • Kandel, E.S.1    Hay, N.2
  • 33
    • 0036316344 scopus 로고    scopus 로고
    • Akt-dependent phosphorylation specifically regulates Cot induction of NF-κB-dependent transcription
    • Kane, L. P., M. N. Mollenauer, Z. Xu, C. W. Turck, and A. Weiss. 2002. Akt-dependent phosphorylation specifically regulates Cot induction of NF-κB-dependent transcription. Mol. Cell. Biol. 22:5962-5974.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 5962-5974
    • Kane, L.P.1    Mollenauer, M.N.2    Xu, Z.3    Turck, C.W.4    Weiss, A.5
  • 37
    • 0033573012 scopus 로고    scopus 로고
    • The in vivo manipulation of carbohydrate metabolism: A new strategy for deciphering the cellular defence mechanisms against nitric oxide attack
    • Le Goffe, C., G. Vallette, A. Jarry, C. Bou-Hanna, and C. L. Laboisse. 1999. The in vivo manipulation of carbohydrate metabolism: a new strategy for deciphering the cellular defence mechanisms against nitric oxide attack. Biochem. J. 344:643-648.
    • (1999) Biochem. J. , vol.344 , pp. 643-648
    • Le Goffe, C.1    Vallette, G.2    Jarry, A.3    Bou-Hanna, C.4    Laboisse, C.L.5
  • 39
    • 0033961280 scopus 로고    scopus 로고
    • Akt suppresses apoptosis by stimulating the transactivation potential of the Re1A/p65 subunit of NF-κB
    • Madrid, L. V., C. Y. Wang, D. C. Guttridge, A. J. Schottelius, A. S. Baldwin, Jr., and M. W. Mayo. 2000. Akt suppresses apoptosis by stimulating the transactivation potential of the Re1A/p65 subunit of NF-κB. Mol. Cell. Biol. 20:1626-1638.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 1626-1638
    • Madrid, L.V.1    Wang, C.Y.2    Guttridge, D.C.3    Schottelius, A.J.4    Baldwin A.S., Jr.5    Mayo, M.W.6
  • 41
    • 0034523187 scopus 로고    scopus 로고
    • Mitochondria-dependent apoptosis and cellular pH regulation
    • Matsuyama, S., and J. C. Reed. 2000. Mitochondria-dependent apoptosis and cellular pH regulation. Cell Death Differ. 7:1155-1165.
    • (2000) Cell Death Differ. , vol.7 , pp. 1155-1165
    • Matsuyama, S.1    Reed, J.C.2
  • 42
    • 0033522391 scopus 로고    scopus 로고
    • Conformation of the Bax C-terminus regulates subcellular location and cell death
    • Nechushtan, A., C. L. Smith, Y. T. Hsu, and R. J. Youle. 1999. Conformation of the Bax C-terminus regulates subcellular location and cell death. EMBO J. 18:2330-2341.
    • (1999) EMBO J. , vol.18 , pp. 2330-2341
    • Nechushtan, A.1    Smith, C.L.2    Hsu, Y.T.3    Youle, R.J.4
  • 45
    • 0025255538 scopus 로고
    • Deregulated Bcl-2 gene expression selectively prolongs survival of growth factor-deprived hemopoietic cell lines
    • Nunez, G., L. London, D. Hockenbery, M. Alexander, J. P. Mckearn, and S. J. Korsmeyer. 1990. Deregulated Bcl-2 gene expression selectively prolongs survival of growth factor-deprived hemopoietic cell lines. J. Immunol. 144:3602-3610.
    • (1990) J. Immunol. , vol.144 , pp. 3602-3610
    • Nunez, G.1    London, L.2    Hockenbery, D.3    Alexander, M.4    Mckearn, J.P.5    Korsmeyer, S.J.6
  • 46
    • 0038393112 scopus 로고    scopus 로고
    • Apoptosis in the development and maintenance of the immune system
    • Opferman, J. T., and S. J. Korsmeyer. 2003. Apoptosis in the development and maintenance of the immune system. Nat. Immunol. 4:410-415.
    • (2003) Nat. Immunol. , vol.4 , pp. 410-415
    • Opferman, J.T.1    Korsmeyer, S.J.2
  • 47
    • 0036510541 scopus 로고    scopus 로고
    • Mitochondria binding of hexokinase II inhibits Bax-induced cytochrome c release and apoptosis
    • Pastorino, J. G., N. Shulga, and J. B. Hoek. 2002. Mitochondria binding of hexokinase II inhibits Bax-induced cytochrome c release and apoptosis. J. Biol. Chem. 277:7610-7618.
    • (2002) J. Biol. Chem. , vol.277 , pp. 7610-7618
    • Pastorino, J.G.1    Shulga, N.2    Hoek, J.B.3
  • 48
    • 0035853833 scopus 로고    scopus 로고
    • Akt and Bcl-xL promote growth factor-independent survival through distinct effects on mitochondrial physiology
    • Plas, D. R., S. Talapatra, A. L. Edinger, J. C. Rathmell, and C. B. Thompson. 2001. Akt and Bcl-xL promote growth factor-independent survival through distinct effects on mitochondrial physiology. J. Biol. Chem. 276:12041-12048.
    • (2001) J. Biol. Chem. , vol.276 , pp. 12041-12048
    • Plas, D.R.1    Talapatra, S.2    Edinger, A.L.3    Rathmell, J.C.4    Thompson, C.B.5
  • 49
    • 0033635249 scopus 로고    scopus 로고
    • In the absence of extrinsic signals, nutrient utilization by lymphocytes is insufficient to maintain either cell size of viability
    • Rathmell, J. C., M. G. Vander Heiden, M. H. Harris, K. A. Frauwirth, and C. B. Thompson. 2000. In the absence of extrinsic signals, nutrient utilization by lymphocytes is insufficient to maintain either cell size of viability. Mol. Cell 6:683-692.
    • (2000) Mol. Cell , vol.6 , pp. 683-692
    • Rathmell, J.C.1    Vander Heiden, M.G.2    Harris, M.H.3    Frauwirth, K.A.4    Thompson, C.B.5
  • 50
    • 0033517190 scopus 로고    scopus 로고
    • NF-κB is a target of AKT in anti-apoptotic PDGF signalling
    • Romashkova, J. A., and S. S. Makarov. 1999. NF-κB is a target of AKT in anti-apoptotic PDGF signalling. Nature 401:86-90.
    • (1999) Nature , vol.401 , pp. 86-90
    • Romashkova, J.A.1    Makarov, S.S.2
  • 51
    • 0014799858 scopus 로고
    • Regulation of D-fructose 1-phosphate kinase by potassium ion
    • Sapico, V., and R. L. Anderson. 1970. Regulation of D-fructose 1-phosphate kinase by potassium ion. J. Biol. Chem. 245:3252-3256.
    • (1970) J. Biol. Chem. , vol.245 , pp. 3252-3256
    • Sapico, V.1    Anderson, R.L.2
  • 52
    • 0036333737 scopus 로고    scopus 로고
    • Multiple phosphoinositide 3-kinase-dependent steps in activation of protein kinase B
    • Scheid, M. P., P. A. Marignani, and J. R. Woodgett. 2002. Multiple phosphoinositide 3-kinase-dependent steps in activation of protein kinase B. Mol. Cell. Biol. 22:6247-6260.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 6247-6260
    • Scheid, M.P.1    Marignani, P.A.2    Woodgett, J.R.3
  • 53
    • 0027134807 scopus 로고
    • Atrophy but not death of adult septal cholinergic neurons after ablation of target capacity to produce mRNAs for NGF, BDNF, and NT3
    • Sofroniew, M. V., J. D. Cooper, C. N. Svendsen, P. Crossman, N. Y. Ip, R. M. Lindsay, and F. Zafra. 1993. Atrophy but not death of adult septal cholinergic neurons after ablation of target capacity to produce mRNAs for NGF, BDNF, and NT3. J. Neurosci. 13:5263-5276.
    • (1993) J. Neurosci. , vol.13 , pp. 5263-5276
    • Sofroniew, M.V.1    Cooper, J.D.2    Svendsen, C.N.3    Crossman, P.4    Ip, N.Y.5    Lindsay, R.M.6    Zafra, F.7
  • 54
    • 0031238860 scopus 로고    scopus 로고
    • Structural determinants for the intracellular localization of the isozymes of mammalian hexokinase: Intracellular localization of fusion constructs incorporating structural elements from the hexokinase isozymes and the green fluorescent protein
    • Sui, D., and J. E. Wilson. 1997. Structural determinants for the intracellular localization of the isozymes of mammalian hexokinase: intracellular localization of fusion constructs incorporating structural elements from the hexokinase isozymes and the green fluorescent protein. Arch. Biochem. Biophys. 345:111-125.
    • (1997) Arch. Biochem. Biophys. , vol.345 , pp. 111-125
    • Sui, D.1    Wilson, J.E.2
  • 56
    • 0037134431 scopus 로고    scopus 로고
    • The phosphatidylinositol 3-kinase (P13K)-Akt pathway suppresses Bax translocation to mitochondria
    • Tsuruta, F., N. Masuyama, and Y. Gotoh. 2002. The phosphatidylinositol 3-kinase (P13K)-Akt pathway suppresses Bax translocation to mitochondria. J. Biol. Chem. 277:14040-14047.
    • (2002) J. Biol. Chem. , vol.277 , pp. 14040-14047
    • Tsuruta, F.1    Masuyama, N.2    Gotoh, Y.3
  • 59
    • 12444279265 scopus 로고
    • On the origin of cancer cells
    • Warburg, O. 1956. On the origin of cancer cells. Science 123:309-314.
    • (1956) Science , vol.123 , pp. 309-314
    • Warburg, O.1
  • 61
    • 0021382386 scopus 로고
    • Haemopoietic cell growth factor mediates cell survival via its action of glucose transport
    • Whetton, A. D., G. W. Brazill, and T. M. Dexter. 1984. Haemopoietic cell growth factor mediates cell survival via its action of glucose transport. EMBO J. 3:409-413.
    • (1984) EMBO J. , vol.3 , pp. 409-413
    • Whetton, A.D.1    Brazill, G.W.2    Dexter, T.M.3
  • 63
    • 0024313144 scopus 로고
    • Rapid purification of mitochondrial hexokinase from rat brain by a single affinity chromatography step on Affi-Gel blue
    • Wilson, J. E. 1989. Rapid purification of mitochondrial hexokinase from rat brain by a single affinity chromatography step on Affi-Gel blue. Prep. Biochem. 19:13-21.
    • (1989) Prep. Biochem. , vol.19 , pp. 13-21
    • Wilson, J.E.1
  • 64
    • 0037693727 scopus 로고    scopus 로고
    • Modulation of the Pasteur effect in retinal cells: Implications for understanding compensatory metabolic mechanisms
    • Winkler, B. S., M. W. Sauer, and C. A. Starnes. 2003. Modulation of the Pasteur effect in retinal cells: implications for understanding compensatory metabolic mechanisms. Exp. Eye Res. 76:715-723.
    • (2003) Exp. Eye Res. , vol.76 , pp. 715-723
    • Winkler, B.S.1    Sauer, M.W.2    Starnes, C.A.3
  • 65
    • 0035936023 scopus 로고    scopus 로고
    • The protein kinase PKB/Akt regulates cell survival and apoptosis by inhibiting Bax conformational change
    • Yamaguchi, H., and H. G. Wang. 2001. The protein kinase PKB/Akt regulates cell survival and apoptosis by inhibiting Bax conformational change. Oncogene 20:7779-7786.
    • (2001) Oncogene , vol.20 , pp. 7779-7786
    • Yamaguchi, H.1    Wang, H.G.2
  • 66
    • 0030772117 scopus 로고    scopus 로고
    • Overexpression of Glut1 and Glut3 in stage I nonsmall cell lung carcinoma is associated with poor survival
    • Younes, M., R. W. Brown, M. Stephenson, M. Gondo, and P. T. Cagle. 1997. Overexpression of Glut1 and Glut3 in stage I nonsmall cell lung carcinoma is associated with poor survival. Cancer 80:1046-1051.
    • (1997) Cancer , vol.80 , pp. 1046-1051
    • Younes, M.1    Brown, R.W.2    Stephenson, M.3    Gondo, M.4    Cagle, P.T.5
  • 67
    • 0029979056 scopus 로고    scopus 로고
    • Overexpression of the human erythrocyte glucose transporter occurs as a late event in human colorectal carcinogenesis and is associated with an increased incidence of lymph node metastases
    • Younes, M., L. V. Lechago, and J. Lechago. 1996. Overexpression of the human erythrocyte glucose transporter occurs as a late event in human colorectal carcinogenesis and is associated with an increased incidence of lymph node metastases. Clin. Cancer Res. 2:1151-1154.
    • (1996) Clin. Cancer Res. , vol.2 , pp. 1151-1154
    • Younes, M.1    Lechago, L.V.2    Lechago, J.3
  • 68
    • 0035876483 scopus 로고    scopus 로고
    • BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak
    • Zong, W. X., T. Lindsten, A. J. Ross, G. R. MacGregor, and C. B. Thompson. 2001. BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak. Genes Dev. 15:1481-1486.
    • (2001) Genes Dev. , vol.15 , pp. 1481-1486
    • Zong, W.X.1    Lindsten, T.2    Ross, A.J.3    MacGregor, G.R.4    Thompson, C.B.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.