-
1
-
-
0037163688
-
Evaluation of 2-deoxy-D-glucose as a chemotherapeutic agent: Mechanism of cell death
-
Aft, R. L., F. W. Zhang, and D. Gius. 2002. Evaluation of 2-deoxy-D-glucose as a chemotherapeutic agent: mechanism of cell death. Br. J. Cancer 87:805-812.
-
(2002)
Br. J. Cancer
, vol.87
, pp. 805-812
-
-
Aft, R.L.1
Zhang, F.W.2
Gius, D.3
-
2
-
-
0031127305
-
Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Bα
-
Alessi, D. R., S. R. James, C. P. Downes, A. B. Holmes, P. R. Gaffney, C. B. Reese, and P. Cohen. 1997. Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Bα. Curr. Biol. 7:261-269.
-
(1997)
Curr. Biol.
, vol.7
, pp. 261-269
-
-
Alessi, D.R.1
James, S.R.2
Downes, C.P.3
Holmes, A.B.4
Gaffney, P.R.5
Reese, C.B.6
Cohen, P.7
-
3
-
-
0031783046
-
ELAV protein HuA (HuR) can redistribute between nucleus and cytoplasm and is upregulated during serum stimulation and T cell activation
-
Atasoy, U., J. Watson, D. Patel, and J. D. Keene. 1998. ELAV protein HuA (HuR) can redistribute between nucleus and cytoplasm and is upregulated during serum stimulation and T cell activation. J. Cell Sci. 111:3145-3156.
-
(1998)
J. Cell Sci.
, vol.111
, pp. 3145-3156
-
-
Atasoy, U.1
Watson, J.2
Patel, D.3
Keene, J.D.4
-
4
-
-
0029550551
-
Trafficking of glucose transporters-signals and mechanisms
-
Baldwin, S. A., L. F. Barros, and M. Griffiths. 1995. Trafficking of glucose transporters-signals and mechanisms. Biosci. Rep. 15:419-426.
-
(1995)
Biosci. Rep.
, vol.15
, pp. 419-426
-
-
Baldwin, S.A.1
Barros, L.F.2
Griffiths, M.3
-
5
-
-
0033575290
-
Regulation of GLUT1 gene transcription by the serine/threonine kinase Akt1
-
Barthel, A., S. T. Okino, J. Liao, K. Nakatani, J. Li, J. P. J. Whitlock, and R. A. Roth, 1999. Regulation of GLUT1 gene transcription by the serine/threonine kinase Akt1. J. Biol. Chem. 274:20281-20286.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 20281-20286
-
-
Barthel, A.1
Okino, S.T.2
Liao, J.3
Nakatani, K.4
Li, J.5
Whitlock, J.P.J.6
Roth, R.A.7
-
6
-
-
0026095665
-
A retroviral oncogene, akt, encoding a serine-threonine kinase containing an SH2-like region
-
Bellacosa, A., J. R. Testa, S. P. Staal, and P. N. Tsichlis. 1991. A retroviral oncogene, akt, encoding a serine-threonine kinase containing an SH2-like region. Science 254:274-277.
-
(1991)
Science
, vol.254
, pp. 274-277
-
-
Bellacosa, A.1
Testa, J.R.2
Staal, S.P.3
Tsichlis, P.N.4
-
7
-
-
0027282044
-
bcl-x, a bcl-2 related gene that functions as a dominant regulator of apoptotic cell death
-
Boise, L. H., M. Gonzalez-Garcia, C. E. Postema, L. Ding, T. Lindsten, L. A. Turka, X. Mao, G. Nunez, and C. B. Thompson. 1993. bcl-x, a bcl-2 related gene that functions as a dominant regulator of apoptotic cell death. Cell 74:597-608.
-
(1993)
Cell
, vol.74
, pp. 597-608
-
-
Boise, L.H.1
Gonzalez-Garcia, M.2
Postema, C.E.3
Ding, L.4
Lindsten, T.5
Turka, L.A.6
Mao, X.7
Nunez, G.8
Thompson, C.B.9
-
8
-
-
0037192787
-
Increased hexokinase activity, of either ectopic or endogenous origin, protects renal epithelial cells against acute oxidant-induced cell death
-
Bryson, J. M., P. E. Coy, K. Gottlob, N. Hay, and R. B. Robey. 2002. Increased hexokinase activity, of either ectopic or endogenous origin, protects renal epithelial cells against acute oxidant-induced cell death. J. Biol. Chem. 277:11392-11400.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 11392-11400
-
-
Bryson, J.M.1
Coy, P.E.2
Gottlob, K.3
Hay, N.4
Robey, R.B.5
-
9
-
-
0035912228
-
Insulin-stimulated GLUT4 translocation requires the CAP-dependent activation of TC10
-
Chiang, S. H., C. A. Baumann, M. Kanzaki, D. C. Thurmond, R. T. Watson, C. L. Neudauer, I. G. Macara, J. E. Pessin, and A. R. Saltiel. 2001. Insulin-stimulated GLUT4 translocation requires the CAP-dependent activation of TC10. Nature 410:944-948.
-
(2001)
Nature
, vol.410
, pp. 944-948
-
-
Chiang, S.H.1
Baumann, C.A.2
Kanzaki, M.3
Thurmond, D.C.4
Watson, R.T.5
Neudauer, C.L.6
Macara, I.G.7
Pessin, J.E.8
Saltiel, A.R.9
-
10
-
-
0026006501
-
Molecular cloning and characterisation of a novel protein-serine kinase related to the cAMP-dependent and protein kinase C families
-
Coffer, P. J., and J. R. Woodgett. 1991. Molecular cloning and characterisation of a novel protein-serine kinase related to the cAMP-dependent and protein kinase C families. Eur. J. Biochem. 201:475-481.
-
(1991)
Eur. J. Biochem.
, vol.201
, pp. 475-481
-
-
Coffer, P.J.1
Woodgett, J.R.2
-
11
-
-
0033593316
-
Size control in animal development
-
Conlon, I., and M. Raff. 1999. Size control in animal development. Cell 96:235-244.
-
(1999)
Cell
, vol.96
, pp. 235-244
-
-
Conlon, I.1
Raff, M.2
-
12
-
-
0027485950
-
Temporal analysis of events associated with programmed cell death (apoptosis) of sympathetic neurons deprived of nerve growth factor
-
Deckwerth, T. L., and E. M. J. Johnson. 1993. Temporal analysis of events associated with programmed cell death (apoptosis) of sympathetic neurons deprived of nerve growth factor. J. Cell Biol. 123:1207-1222.
-
(1993)
J. Cell Biol.
, vol.123
, pp. 1207-1222
-
-
Deckwerth, T.L.1
Johnson, E.M.J.2
-
13
-
-
0030458720
-
Genetic and metabolic status of NGF-deprived sympathetic neurons saved by an inhibitor or ICE family proteases
-
Deshmukh, M., J. Vasilakos, T. L. Deckwerth, P. A. Lampe, B. D. Shivers, and E. M. J. Johnson. 1996. Genetic and metabolic status of NGF-deprived sympathetic neurons saved by an inhibitor or ICE family proteases. J. Cell Biol. 135:1341-1354.
-
(1996)
J. Cell Biol.
, vol.135
, pp. 1341-1354
-
-
Deshmukh, M.1
Vasilakos, J.2
Deckwerth, T.L.3
Lampe, P.A.4
Shivers, B.D.5
Johnson, E.M.J.6
-
14
-
-
0036236508
-
Molecular mechanisms of insulin-stimulated glucose uptake in adipocytes
-
Ducluzeau, P. H., L. M. Fletcher, H. Vidal, M. Laville, and J. M. Tavare. 2002. Molecular mechanisms of insulin-stimulated glucose uptake in adipocytes. Diabetes Metab. 28:85-92.
-
(2002)
Diabetes Metab.
, vol.28
, pp. 85-92
-
-
Ducluzeau, P.H.1
Fletcher, L.M.2
Vidal, H.3
Laville, M.4
Tavare, J.M.5
-
15
-
-
0036320205
-
Akt maintains cell size and survival by increasing mTOR-dependent nutrient uptake
-
Edinger, A. L., and C. B. Thompson. 2002. Akt maintains cell size and survival by increasing mTOR-dependent nutrient uptake. Mol. Biol. Cell 13:2276-2288.
-
(2002)
Mol. Biol. Cell
, vol.13
, pp. 2276-2288
-
-
Edinger, A.L.1
Thompson, C.B.2
-
16
-
-
0033215390
-
Protein kinase B stimulates the translocation of GLUT4 but not GLUT1 or transferrin receptors in 3T3-L1 adipocytes by a pathway involving SNAP-23, synaptobrevin-2, and/or cellubrevin
-
Foran, P. G. P., L. M. Fletcher, P. B. Oatey, N. Mohammed, J. O. Dolly, and J. M. Tavare. 1999. Protein kinase B stimulates the translocation of GLUT4 but not GLUT1 or transferrin receptors in 3T3-L1 adipocytes by a pathway involving SNAP-23, synaptobrevin-2, and/or cellubrevin. J. Biol. Chem. 274:28087-28095.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 28087-28095
-
-
Foran, P.G.P.1
Fletcher, L.M.2
Oatey, P.B.3
Mohammed, N.4
Dolly, J.O.5
Tavare, J.M.6
-
17
-
-
0032494166
-
Control of neuronal size homeostasis by trophic factor-mediated coupling of protein degradation to protein synthesis
-
Franklin, J. L., and E. M. Johnson. 1998. Control of neuronal size homeostasis by trophic factor-mediated coupling of protein degradation to protein synthesis. J. Cell Biol. 142:1313-1324.
-
(1998)
J. Cell Biol.
, vol.142
, pp. 1313-1324
-
-
Franklin, J.L.1
Johnson, E.M.2
-
18
-
-
0036069699
-
The CD28 signaling pathway regulates glucose metabolism
-
Frauwirth, K. A., J. L. Riley, M. H. Harris, R. V. Parry, J. C. Rathmell, D. R. Plas, R. L. Elstrom, C. H. June, and C. B. Thompson. 2002. The CD28 signaling pathway regulates glucose metabolism. Immunity 16:769-777.
-
(2002)
Immunity
, vol.16
, pp. 769-777
-
-
Frauwirth, K.A.1
Riley, J.L.2
Harris, M.H.3
Parry, R.V.4
Rathmell, J.C.5
Plas, D.R.6
Elstrom, R.L.7
June, C.H.8
Thompson, C.B.9
-
19
-
-
0036792001
-
Mitochondrial respiratory control is lost during growth factor deprivation
-
Gottlieb, E., S. M. Armour, and C. B. Thompson. 2002. Mitochondrial respiratory control is lost during growth factor deprivation. Proc. Natl. Acad. Sci. USA 99:12801-12806.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 12801-12806
-
-
Gottlieb, E.1
Armour, S.M.2
Thompson, C.B.3
-
20
-
-
0034983918
-
Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase
-
Gottlob, K., N. Majewski, S. Kennedy, E. Kandel, R. B. Robey, and N. Hay. 2001. Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase. Genes Dev. 15:1406-1418.
-
(2001)
Genes Dev.
, vol.15
, pp. 1406-1418
-
-
Gottlob, K.1
Majewski, N.2
Kennedy, S.3
Kandel, E.4
Robey, R.B.5
Hay, N.6
-
21
-
-
0032528118
-
Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis
-
Gross, A., J. Jockel, M. C. Wei, and S. J. Korsmeyer. 1998. Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis. EMBO J. 17:3878-3885.
-
(1998)
EMBO J.
, vol.17
, pp. 3878-3885
-
-
Gross, A.1
Jockel, J.2
Wei, M.C.3
Korsmeyer, S.J.4
-
22
-
-
0034781048
-
Iodoacetate protects hippocampal neurons against excitotoxic and oxidative injury: Involvement of heat-shock proteins and Bcl-2
-
Guo, Z., J. Lee, M. Lane, and M. Mattson. 2001. Iodoacetate protects hippocampal neurons against excitotoxic and oxidative injury: involvement of heat-shock proteins and Bcl-2. J. Neurochem. 79:361-370.
-
(2001)
J. Neurochem.
, vol.79
, pp. 361-370
-
-
Guo, Z.1
Lee, J.2
Lane, M.3
Mattson, M.4
-
23
-
-
0035896366
-
Protein kinase B (PKB/Akt) - A key regulator of glucose transport?
-
Hajduch, E., G. J. Litherland, and H. S. Hundal. 2001. Protein kinase B (PKB/Akt) - a key regulator of glucose transport? FEBS Lett. 492:199-203.
-
(2001)
FEBS Lett.
, vol.492
, pp. 199-203
-
-
Hajduch, E.1
Litherland, G.J.2
Hundal, H.S.3
-
24
-
-
0032695529
-
A role for protein kinase Bβ/Akt2 in insulin-stimulated GLUT4 translocation in adipocytes
-
Hill, M. M., S. F. Clark, D. F. Tucker, M. J. Birnbaum, D. E. James, and S. L. Macaulay. 1999. A role for protein kinase Bβ/Akt2 in insulin-stimulated GLUT4 translocation in adipocytes. Mol. Cell. Biol. 19:7771-7781.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 7771-7781
-
-
Hill, M.M.1
Clark, S.F.2
Tucker, D.F.3
Birnbaum, M.J.4
James, D.E.5
Macaulay, S.L.6
-
25
-
-
0025204548
-
Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death
-
Hockenbery, D., G. Nunez, C. Milliman, R. D. Schreiber, and S. J, Korsmeyer. 1990. Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. Nature 348:334-336.
-
(1990)
Nature
, vol.348
, pp. 334-336
-
-
Hockenbery, D.1
Nunez, G.2
Milliman, C.3
Schreiber, R.D.4
Korsmeyer, S.J.5
-
26
-
-
0033032863
-
Glucose transporter expression in developing fetal lungs and lung neoplasms
-
Ito, T., Y. Noguchi, N. Udaka, H. Kitamura, and S. Satoh. 1999. Glucose transporter expression in developing fetal lungs and lung neoplasms. Histol. Histopathol. 14:895-904.
-
(1999)
Histol. Histopathol.
, vol.14
, pp. 895-904
-
-
Ito, T.1
Noguchi, Y.2
Udaka, N.3
Kitamura, H.4
Satoh, S.5
-
27
-
-
0031038858
-
Ectopic expression of Hel-N1, an RNA-binding protein, increases glucose transporter (GLUT1) expression in 3T3-L1 adipocytes
-
Jain, R. G., L. G. Andrews, K. M. McGowan, P. H. Pekala, and J. D. Keene. 1997. Ectopic expression of Hel-N1, an RNA-binding protein, increases glucose transporter (GLUT1) expression in 3T3-L1 adipocytes. Mol. Cell. Biol. 17:954-962.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 954-962
-
-
Jain, R.G.1
Andrews, L.G.2
McGowan, K.M.3
Pekala, P.H.4
Keene, J.D.5
-
28
-
-
0025882091
-
Molecular cloning and identification of a serine/theonine protein kinase of the second-messenger subfamily
-
Jones, P. F., T. Jakubowicz, F. J. Pitossi, F. Maurer, and B. A. Hemmings. 1991. Molecular cloning and identification of a serine/theonine protein kinase of the second-messenger subfamily. Proc. Natl. Acad. Sci. USA 88:4171-4175.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 4171-4175
-
-
Jones, P.F.1
Jakubowicz, T.2
Pitossi, F.J.3
Maurer, F.4
Hemmings, B.A.5
-
30
-
-
0032574761
-
Bax directly induces cytochrome c from isolated mitochondria
-
Jurgensmeier, J. M., Q. Deveraux, L. Ellerby, D. Bredensen, and J. C. Reed. 1998. Bax directly induces cytochrome c from isolated mitochondria. Proc. Natl. Acad. Sci. USA 95:4997-5002.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 4997-5002
-
-
Jurgensmeier, J.M.1
Deveraux, Q.2
Ellerby, L.3
Bredensen, D.4
Reed, J.C.5
-
31
-
-
0034805635
-
Detection of aquaporin-2 in the plasma membranes of oocytes: A novel isolation method with improved yield and purity
-
Kamsteeg, E.-J., and P. M. T. Deen. 2001. Detection of aquaporin-2 in the plasma membranes of oocytes: a novel isolation method with improved yield and purity. Biochem. Biophys. Res. Commun. 282:683-690.
-
(2001)
Biochem. Biophys. Res. Commun.
, vol.282
, pp. 683-690
-
-
Kamsteeg, E.-J.1
Deen, P.M.T.2
-
32
-
-
0033604585
-
The regulation and activities of the multi-functional serine/threonine kinase Akt/PKB
-
Kandel, E. S., and N. Hay. 1999. The regulation and activities of the multi-functional serine/threonine kinase Akt/PKB. Exp. Cell Res. 253:210-229.
-
(1999)
Exp. Cell Res.
, vol.253
, pp. 210-229
-
-
Kandel, E.S.1
Hay, N.2
-
33
-
-
0036316344
-
Akt-dependent phosphorylation specifically regulates Cot induction of NF-κB-dependent transcription
-
Kane, L. P., M. N. Mollenauer, Z. Xu, C. W. Turck, and A. Weiss. 2002. Akt-dependent phosphorylation specifically regulates Cot induction of NF-κB-dependent transcription. Mol. Cell. Biol. 22:5962-5974.
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 5962-5974
-
-
Kane, L.P.1
Mollenauer, M.N.2
Xu, Z.3
Turck, C.W.4
Weiss, A.5
-
34
-
-
0033519453
-
Induction of NF-κB by the Akt/PKB kinase
-
Kane, L. P., V. S. Shapiro, D. Stokoe, and A. Weiss. 1999. Induction of NF-κB by the Akt/PKB kinase. Curr. Biol. 9:601-604.
-
(1999)
Curr. Biol.
, vol.9
, pp. 601-604
-
-
Kane, L.P.1
Shapiro, V.S.2
Stokoe, D.3
Weiss, A.4
-
35
-
-
0036808431
-
Clinical significance of glucose transporter 1 (GLUT1) expression in human breast carcinoma
-
Kang, S. S., Y. K. Chun, M. H. Hur, H. K. Lee, Y. J. Kim, S. R. Hong, J. H. Lee, S. G. Lee, and Y. K. Park. 2002. Clinical significance of glucose transporter 1 (GLUT1) expression in human breast carcinoma. Jpn. J. Cancer Res. 93:1123-1128.
-
(2002)
Jpn. J. Cancer Res.
, vol.93
, pp. 1123-1128
-
-
Kang, S.S.1
Chun, Y.K.2
Hur, M.H.3
Lee, H.K.4
Kim, Y.J.5
Hong, S.R.6
Lee, J.H.7
Lee, S.G.8
Park, Y.K.9
-
37
-
-
0033573012
-
The in vivo manipulation of carbohydrate metabolism: A new strategy for deciphering the cellular defence mechanisms against nitric oxide attack
-
Le Goffe, C., G. Vallette, A. Jarry, C. Bou-Hanna, and C. L. Laboisse. 1999. The in vivo manipulation of carbohydrate metabolism: a new strategy for deciphering the cellular defence mechanisms against nitric oxide attack. Biochem. J. 344:643-648.
-
(1999)
Biochem. J.
, vol.344
, pp. 643-648
-
-
Le Goffe, C.1
Vallette, G.2
Jarry, A.3
Bou-Hanna, C.4
Laboisse, C.L.5
-
38
-
-
0034508217
-
The combined functions of proapoptotic Bcl-2 family members Bak and Bax are essential for normal development of multiple tissues
-
Lindsten, T., A. J. Ross, A. King, W. X. Zong, J. C. Rathmell, H. A. Shiels, E. Ulrich, K. G. Waymire, P. Mahar, K. Frauwirth, Y. Chen, M. Wei, V. M. Eng, D. M. Adelman, M. C. Simon, A. Ma, J. A. Golden, G. Evan, S. J. Korsmeyer, G. R. MacGregor, and C. B. Thompson. 2000. The combined functions of proapoptotic Bcl-2 family members Bak and Bax are essential for normal development of multiple tissues. Mol. Cell 6:1389-1399.
-
(2000)
Mol. Cell
, vol.6
, pp. 1389-1399
-
-
Lindsten, T.1
Ross, A.J.2
King, A.3
Zong, W.X.4
Rathmell, J.C.5
Shiels, H.A.6
Ulrich, E.7
Waymire, K.G.8
Mahar, P.9
Frauwirth, K.10
Chen, Y.11
Wei, M.12
Eng, V.M.13
Adelman, D.M.14
Simon, M.C.15
Ma, A.16
Golden, J.A.17
Evan, G.18
Korsmeyer, S.J.19
MacGregor, G.R.20
Thompson, C.B.21
more..
-
39
-
-
0033961280
-
Akt suppresses apoptosis by stimulating the transactivation potential of the Re1A/p65 subunit of NF-κB
-
Madrid, L. V., C. Y. Wang, D. C. Guttridge, A. J. Schottelius, A. S. Baldwin, Jr., and M. W. Mayo. 2000. Akt suppresses apoptosis by stimulating the transactivation potential of the Re1A/p65 subunit of NF-κB. Mol. Cell. Biol. 20:1626-1638.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 1626-1638
-
-
Madrid, L.V.1
Wang, C.Y.2
Guttridge, D.C.3
Schottelius, A.J.4
Baldwin A.S., Jr.5
Mayo, M.W.6
-
40
-
-
0034999880
-
Cisplatin induces the proapoptotic conformation of Bak in a ΔMEKK1-dependent manner
-
Mandic, A., K. Viktorsson, M. Molin, G. Akusjarvi, H. Eguchi, S. I. Hayashi, M. Toi, J. Hansson, S. Linder, and M. C. Shoshan. 2001. Cisplatin induces the proapoptotic conformation of Bak in a ΔMEKK1-dependent manner. Mol. Cell. Biol. 21:3684-3691.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 3684-3691
-
-
Mandic, A.1
Viktorsson, K.2
Molin, M.3
Akusjarvi, G.4
Eguchi, H.5
Hayashi, S.I.6
Toi, M.7
Hansson, J.8
Linder, S.9
Shoshan, M.C.10
-
41
-
-
0034523187
-
Mitochondria-dependent apoptosis and cellular pH regulation
-
Matsuyama, S., and J. C. Reed. 2000. Mitochondria-dependent apoptosis and cellular pH regulation. Cell Death Differ. 7:1155-1165.
-
(2000)
Cell Death Differ.
, vol.7
, pp. 1155-1165
-
-
Matsuyama, S.1
Reed, J.C.2
-
42
-
-
0033522391
-
Conformation of the Bax C-terminus regulates subcellular location and cell death
-
Nechushtan, A., C. L. Smith, Y. T. Hsu, and R. J. Youle. 1999. Conformation of the Bax C-terminus regulates subcellular location and cell death. EMBO J. 18:2330-2341.
-
(1999)
EMBO J.
, vol.18
, pp. 2330-2341
-
-
Nechushtan, A.1
Smith, C.L.2
Hsu, Y.T.3
Youle, R.J.4
-
43
-
-
24244465637
-
-
Academic Press, London, England
-
Nicholls, D. G., and S. J. Ferguson. 1992. Bioenergetics 2, 2nd. ed. Academic Press, London, England.
-
(1992)
Bioenergetics 2, 2nd. Ed.
-
-
Nicholls, D.G.1
Ferguson, S.J.2
-
44
-
-
0034733953
-
Suppression of facilitative glucose transporter 1 mRNA can suppress tumor growth
-
Noguchi, Y., A. Saito, Y. Miyagi, S. Yamanaka, D. Marat, C. Doi, T. Yoshikawa, A. Tsuburaya, T. Ito, and S. Satoh. 2000. Suppression of facilitative glucose transporter 1 mRNA can suppress tumor growth. Cancer Lett. 154:175-182.
-
(2000)
Cancer Lett.
, vol.154
, pp. 175-182
-
-
Noguchi, Y.1
Saito, A.2
Miyagi, Y.3
Yamanaka, S.4
Marat, D.5
Doi, C.6
Yoshikawa, T.7
Tsuburaya, A.8
Ito, T.9
Satoh, S.10
-
45
-
-
0025255538
-
Deregulated Bcl-2 gene expression selectively prolongs survival of growth factor-deprived hemopoietic cell lines
-
Nunez, G., L. London, D. Hockenbery, M. Alexander, J. P. Mckearn, and S. J. Korsmeyer. 1990. Deregulated Bcl-2 gene expression selectively prolongs survival of growth factor-deprived hemopoietic cell lines. J. Immunol. 144:3602-3610.
-
(1990)
J. Immunol.
, vol.144
, pp. 3602-3610
-
-
Nunez, G.1
London, L.2
Hockenbery, D.3
Alexander, M.4
Mckearn, J.P.5
Korsmeyer, S.J.6
-
46
-
-
0038393112
-
Apoptosis in the development and maintenance of the immune system
-
Opferman, J. T., and S. J. Korsmeyer. 2003. Apoptosis in the development and maintenance of the immune system. Nat. Immunol. 4:410-415.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 410-415
-
-
Opferman, J.T.1
Korsmeyer, S.J.2
-
47
-
-
0036510541
-
Mitochondria binding of hexokinase II inhibits Bax-induced cytochrome c release and apoptosis
-
Pastorino, J. G., N. Shulga, and J. B. Hoek. 2002. Mitochondria binding of hexokinase II inhibits Bax-induced cytochrome c release and apoptosis. J. Biol. Chem. 277:7610-7618.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 7610-7618
-
-
Pastorino, J.G.1
Shulga, N.2
Hoek, J.B.3
-
48
-
-
0035853833
-
Akt and Bcl-xL promote growth factor-independent survival through distinct effects on mitochondrial physiology
-
Plas, D. R., S. Talapatra, A. L. Edinger, J. C. Rathmell, and C. B. Thompson. 2001. Akt and Bcl-xL promote growth factor-independent survival through distinct effects on mitochondrial physiology. J. Biol. Chem. 276:12041-12048.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 12041-12048
-
-
Plas, D.R.1
Talapatra, S.2
Edinger, A.L.3
Rathmell, J.C.4
Thompson, C.B.5
-
49
-
-
0033635249
-
In the absence of extrinsic signals, nutrient utilization by lymphocytes is insufficient to maintain either cell size of viability
-
Rathmell, J. C., M. G. Vander Heiden, M. H. Harris, K. A. Frauwirth, and C. B. Thompson. 2000. In the absence of extrinsic signals, nutrient utilization by lymphocytes is insufficient to maintain either cell size of viability. Mol. Cell 6:683-692.
-
(2000)
Mol. Cell
, vol.6
, pp. 683-692
-
-
Rathmell, J.C.1
Vander Heiden, M.G.2
Harris, M.H.3
Frauwirth, K.A.4
Thompson, C.B.5
-
50
-
-
0033517190
-
NF-κB is a target of AKT in anti-apoptotic PDGF signalling
-
Romashkova, J. A., and S. S. Makarov. 1999. NF-κB is a target of AKT in anti-apoptotic PDGF signalling. Nature 401:86-90.
-
(1999)
Nature
, vol.401
, pp. 86-90
-
-
Romashkova, J.A.1
Makarov, S.S.2
-
51
-
-
0014799858
-
Regulation of D-fructose 1-phosphate kinase by potassium ion
-
Sapico, V., and R. L. Anderson. 1970. Regulation of D-fructose 1-phosphate kinase by potassium ion. J. Biol. Chem. 245:3252-3256.
-
(1970)
J. Biol. Chem.
, vol.245
, pp. 3252-3256
-
-
Sapico, V.1
Anderson, R.L.2
-
52
-
-
0036333737
-
Multiple phosphoinositide 3-kinase-dependent steps in activation of protein kinase B
-
Scheid, M. P., P. A. Marignani, and J. R. Woodgett. 2002. Multiple phosphoinositide 3-kinase-dependent steps in activation of protein kinase B. Mol. Cell. Biol. 22:6247-6260.
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 6247-6260
-
-
Scheid, M.P.1
Marignani, P.A.2
Woodgett, J.R.3
-
53
-
-
0027134807
-
Atrophy but not death of adult septal cholinergic neurons after ablation of target capacity to produce mRNAs for NGF, BDNF, and NT3
-
Sofroniew, M. V., J. D. Cooper, C. N. Svendsen, P. Crossman, N. Y. Ip, R. M. Lindsay, and F. Zafra. 1993. Atrophy but not death of adult septal cholinergic neurons after ablation of target capacity to produce mRNAs for NGF, BDNF, and NT3. J. Neurosci. 13:5263-5276.
-
(1993)
J. Neurosci.
, vol.13
, pp. 5263-5276
-
-
Sofroniew, M.V.1
Cooper, J.D.2
Svendsen, C.N.3
Crossman, P.4
Ip, N.Y.5
Lindsay, R.M.6
Zafra, F.7
-
54
-
-
0031238860
-
Structural determinants for the intracellular localization of the isozymes of mammalian hexokinase: Intracellular localization of fusion constructs incorporating structural elements from the hexokinase isozymes and the green fluorescent protein
-
Sui, D., and J. E. Wilson. 1997. Structural determinants for the intracellular localization of the isozymes of mammalian hexokinase: intracellular localization of fusion constructs incorporating structural elements from the hexokinase isozymes and the green fluorescent protein. Arch. Biochem. Biophys. 345:111-125.
-
(1997)
Arch. Biochem. Biophys.
, vol.345
, pp. 111-125
-
-
Sui, D.1
Wilson, J.E.2
-
55
-
-
0032787346
-
Signaling pathways mediating insulin-stimulated glucose transport
-
Summers, S. A., V. P. Yin, E. L. Whiteman, L. A. Garza, H. Cho, R. L. Tuttle, and M. J. Birnbaum. 1999. Signaling pathways mediating insulin-stimulated glucose transport. Ann. N. Y. Acad. Sci. 892:169-186.
-
(1999)
Ann. N. Y. Acad. Sci.
, vol.892
, pp. 169-186
-
-
Summers, S.A.1
Yin, V.P.2
Whiteman, E.L.3
Garza, L.A.4
Cho, H.5
Tuttle, R.L.6
Birnbaum, M.J.7
-
56
-
-
0037134431
-
The phosphatidylinositol 3-kinase (P13K)-Akt pathway suppresses Bax translocation to mitochondria
-
Tsuruta, F., N. Masuyama, and Y. Gotoh. 2002. The phosphatidylinositol 3-kinase (P13K)-Akt pathway suppresses Bax translocation to mitochondria. J. Biol. Chem. 277:14040-14047.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 14040-14047
-
-
Tsuruta, F.1
Masuyama, N.2
Gotoh, Y.3
-
57
-
-
0030613796
-
Bcl-xL regulates the membrane potential and volume homeostasis of mitochondria
-
Vander Heiden, M. G., N. S. Chandel, E. K. Williamson, P. T. Schumacker, and C. B. Thompson. 1997. Bcl-xL regulates the membrane potential and volume homeostasis of mitochondria. Cell 91:627-637.
-
(1997)
Cell
, vol.91
, pp. 627-637
-
-
Vander Heiden, M.G.1
Chandel, N.S.2
Williamson, E.K.3
Schumacker, P.T.4
Thompson, C.B.5
-
58
-
-
0034904776
-
Growth factors can influence cell growth and survival through effects on glucose metabolism
-
Vander Heiden, M. G., D. R. Plas, J. C. Rathmell, C. J. Fox, M. H. Harris, and C. B. Thompson. 2001. Growth factors can influence cell growth and survival through effects on glucose metabolism. Mol. Cell. Biol. 21:5899-5912.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 5899-5912
-
-
Vander Heiden, M.G.1
Plas, D.R.2
Rathmell, J.C.3
Fox, C.J.4
Harris, M.H.5
Thompson, C.B.6
-
59
-
-
12444279265
-
On the origin of cancer cells
-
Warburg, O. 1956. On the origin of cancer cells. Science 123:309-314.
-
(1956)
Science
, vol.123
, pp. 309-314
-
-
Warburg, O.1
-
60
-
-
0035957653
-
Proapoptotic BAX and BAK: A requisite gateway to mitochondrial dysfunction and death
-
Wei, M. C., W. X. Zong, E. H. Cheng, T. Lindsten, V. Panoutsakopoulou, A. J. Ross, K. A. Roth, G. R. MacGregor, C. B. Thompson, and S. J. Korsmeyer. 2001. Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death. Science 292:727-730.
-
(2001)
Science
, vol.292
, pp. 727-730
-
-
Wei, M.C.1
Zong, W.X.2
Cheng, E.H.3
Lindsten, T.4
Panoutsakopoulou, V.5
Ross, A.J.6
Roth, K.A.7
MacGregor, G.R.8
Thompson, C.B.9
Korsmeyer, S.J.10
-
61
-
-
0021382386
-
Haemopoietic cell growth factor mediates cell survival via its action of glucose transport
-
Whetton, A. D., G. W. Brazill, and T. M. Dexter. 1984. Haemopoietic cell growth factor mediates cell survival via its action of glucose transport. EMBO J. 3:409-413.
-
(1984)
EMBO J.
, vol.3
, pp. 409-413
-
-
Whetton, A.D.1
Brazill, G.W.2
Dexter, T.M.3
-
63
-
-
0024313144
-
Rapid purification of mitochondrial hexokinase from rat brain by a single affinity chromatography step on Affi-Gel blue
-
Wilson, J. E. 1989. Rapid purification of mitochondrial hexokinase from rat brain by a single affinity chromatography step on Affi-Gel blue. Prep. Biochem. 19:13-21.
-
(1989)
Prep. Biochem.
, vol.19
, pp. 13-21
-
-
Wilson, J.E.1
-
64
-
-
0037693727
-
Modulation of the Pasteur effect in retinal cells: Implications for understanding compensatory metabolic mechanisms
-
Winkler, B. S., M. W. Sauer, and C. A. Starnes. 2003. Modulation of the Pasteur effect in retinal cells: implications for understanding compensatory metabolic mechanisms. Exp. Eye Res. 76:715-723.
-
(2003)
Exp. Eye Res.
, vol.76
, pp. 715-723
-
-
Winkler, B.S.1
Sauer, M.W.2
Starnes, C.A.3
-
65
-
-
0035936023
-
The protein kinase PKB/Akt regulates cell survival and apoptosis by inhibiting Bax conformational change
-
Yamaguchi, H., and H. G. Wang. 2001. The protein kinase PKB/Akt regulates cell survival and apoptosis by inhibiting Bax conformational change. Oncogene 20:7779-7786.
-
(2001)
Oncogene
, vol.20
, pp. 7779-7786
-
-
Yamaguchi, H.1
Wang, H.G.2
-
66
-
-
0030772117
-
Overexpression of Glut1 and Glut3 in stage I nonsmall cell lung carcinoma is associated with poor survival
-
Younes, M., R. W. Brown, M. Stephenson, M. Gondo, and P. T. Cagle. 1997. Overexpression of Glut1 and Glut3 in stage I nonsmall cell lung carcinoma is associated with poor survival. Cancer 80:1046-1051.
-
(1997)
Cancer
, vol.80
, pp. 1046-1051
-
-
Younes, M.1
Brown, R.W.2
Stephenson, M.3
Gondo, M.4
Cagle, P.T.5
-
67
-
-
0029979056
-
Overexpression of the human erythrocyte glucose transporter occurs as a late event in human colorectal carcinogenesis and is associated with an increased incidence of lymph node metastases
-
Younes, M., L. V. Lechago, and J. Lechago. 1996. Overexpression of the human erythrocyte glucose transporter occurs as a late event in human colorectal carcinogenesis and is associated with an increased incidence of lymph node metastases. Clin. Cancer Res. 2:1151-1154.
-
(1996)
Clin. Cancer Res.
, vol.2
, pp. 1151-1154
-
-
Younes, M.1
Lechago, L.V.2
Lechago, J.3
-
68
-
-
0035876483
-
BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak
-
Zong, W. X., T. Lindsten, A. J. Ross, G. R. MacGregor, and C. B. Thompson. 2001. BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak. Genes Dev. 15:1481-1486.
-
(2001)
Genes Dev.
, vol.15
, pp. 1481-1486
-
-
Zong, W.X.1
Lindsten, T.2
Ross, A.J.3
MacGregor, G.R.4
Thompson, C.B.5
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