Stress-mediated translational control in cancer cells

Biochimica et Biophysica Acta - Gene Regulatory Mechanisms

Volumn 1849, Issue 7, 2015, Pages 845-860

  Leprivier, Gabriel ^a,b   Rotblat, Barak ^c   Khan, Debjit ^a,b   Jan, Eric ^b   Sorensen, Poul H ^a,b  

^a BRITISH COLUMBIA CANCER RESEARCH CENTRE   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

Author keywords

EEF2K; EIF2alpha; MRNA translation control; MTORC1; Stress response; Tumor adaptation

Indexed keywords

EEF2 PROTEIN; EEF2K PROTEIN; ELONGATION FACTOR 2 KINASE; INITIATION FACTOR 2ALPHA; INITIATION FACTOR 4E; INITIATION FACTOR 4E BINDING PROTEIN 1; INITIATION FACTOR 4E BINDING PROTEIN 2; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; MEMBRANE PROTEIN; MESSENGER RNA; UNCLASSIFIED DRUG; INITIATION FACTOR 2; MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1; MULTIPROTEIN COMPLEX; RNA; TARGET OF RAPAMYCIN KINASE; TUMOR PROTEIN;

CANCER CELL; CELL STRESS; GENOTOXIC STRESS; HUMAN; HYPOXIA; INTERNAL RIBOSOME ENTRY SITE; NONHUMAN; NUTRIENT; ONCOLOGICAL PARAMETERS; OPEN READING FRAME; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN SYNTHESIS; REVIEW; RNA TRANSLATION; SIGNAL TRANSDUCTION; STRESS; TUMOR HYPOXIA; ANIMAL; DNA DAMAGE; GENETICS; METABOLISM; NEOPLASM; PATHOLOGY;

ANIMALS; DNA DAMAGE; EUKARYOTIC INITIATION FACTOR-2; HUMANS; MULTIPROTEIN COMPLEXES; NEOPLASM PROTEINS; NEOPLASMS; PROTEIN BIOSYNTHESIS; RNA, MESSENGER; RNA, NEOPLASM; TOR SERINE-THREONINE KINASES;

EID: 84930958887     PISSN: 18749399     EISSN: 18764320     Source Type: Journal    
DOI: 10.1016/j.bbagrm.2014.11.002     Document Type: Review

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