Phosphorylation of eIF2α is required for mRNA translation inhibition and survival during moderate hypoxia

Radiotherapy and Oncology

Volumn 83, Issue 3, 2007, Pages 353-361

  Koritzinsky, Marianne ^a   Rouschop, Kasper M A ^a   van den Beucken, Twan ^a   Magagnin, Michaël G ^a   Savelkouls, Kim ^a   Lambin, Philippe ^a   Wouters, Bradly G ^a  

^a MAASTRICHT UNIVERSITY   (Netherlands)

Author keywords

eIF2 ; Hypoxia; mRNA translation

Indexed keywords

MESSENGER RNA; OXYGEN; PROTEIN ELF 2 A; PROTEIN GADD 34; SHORT HAIRPIN RNA; TETRACYCLINE; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; INITIATION FACTOR 2;

ARTICLE; CANCER CELL CULTURE; CELL IMMORTALIZATION; CELL LINE; CELL PROLIFERATION; CONTROLLED STUDY; FIBROBLAST; GENE MUTATION; HELA CELL; HUMAN; HUMAN CELL; HYPOXIA; POLYSOME; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; RNA TRANSLATION; ANIMAL; BIOSYNTHESIS; CELL HYPOXIA; CELL SURVIVAL; FEMALE; GENETICS; MALE; METABOLISM; MOUSE; PHOSPHORYLATION; PHYSIOLOGY; SIGNAL TRANSDUCTION; TUMOR CELL LINE; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CELL HYPOXIA; CELL LINE, TUMOR; CELL SURVIVAL; EUKARYOTIC INITIATION FACTOR-2; FEMALE; HUMANS; MALE; MICE; PHOSPHORYLATION; PROTEIN BIOSYNTHESIS; RNA, MESSENGER; SIGNAL TRANSDUCTION;

EID: 34250205154     PISSN: 01678140     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.radonc.2007.04.031     Document Type: Article

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