Hypoxia-inducible factor-1α (HIF-1α) promotes cap-dependent translation of selective mRNAs through up-regulating initiation factor eIF4E1 in breast cancer cells under hypoxia conditions

Journal of Biological Chemistry

Volumn 288, Issue 26, 2013, Pages 18732-18742

  Yi, Tingfang ^a   Papadopoulos, Evangelos ^a   Hagner, Patrick R ^a   Wagner, Gerhard ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHESIS; PROTEINS;

BREAST CANCER CELLS; CELLULAR PROCESS; CHROMATIN IMMUNOPRECIPITATION; ENCODING PROTEINS; HYPOXIA INDUCIBLE FACTOR-1 ALPHA; HYPOXIA RESPONSE ELEMENTS; INITIATION FACTORS; PROTEIN SYNTHESIS;

DISEASES;

CELL PROTEIN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INITIATION FACTOR; INITIATION FACTOR EIF4E1; INITIATION FACTOR EIF4E2; INITIATION FACTOR EIF4E3; LUCIFERASE; MESSENGER RNA; OXYGEN; PROTEIN CAP; UNCLASSIFIED DRUG;

ARTICLE; BREAST CANCER; BREAST CARCINOGENESIS; CANCER CELL CULTURE; CANCER GROWTH; CELL HYPOXIA; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DNA STRUCTURE; HUMAN; HUMAN CELL; HYPOXIA RESPONSE ELEMENT; POINT MUTATION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; TRANSLATION REGULATION; UPREGULATION;

EID: 84879574106     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.471466     Document Type: Article

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