-
1
-
-
0037028305
-
Tuberin, the tuberous sclerosis complex 2 tumor suppressor gene product, regulates Rho activation, cell adhesion and migration
-
Astrinidis A., Cash T.P., Hunter D.S., Walker C.L., Chernoff J., and Henske E.P. Tuberin, the tuberous sclerosis complex 2 tumor suppressor gene product, regulates Rho activation, cell adhesion and migration. Oncogene 21 (2002) 8470-8476
-
(2002)
Oncogene
, vol.21
, pp. 8470-8476
-
-
Astrinidis, A.1
Cash, T.P.2
Hunter, D.S.3
Walker, C.L.4
Chernoff, J.5
Henske, E.P.6
-
2
-
-
33750044299
-
When translation meets transformation: The mTOR story
-
Averous J., and Proud C.G. When translation meets transformation: The mTOR story. Oncogene 25 (2006) 6423-6435
-
(2006)
Oncogene
, vol.25
, pp. 6423-6435
-
-
Averous, J.1
Proud, C.G.2
-
3
-
-
39149093333
-
Regulation of cyclin D1 expression by mTORC1 signaling requires eukaryotic initiation factor 4E-binding protein 1
-
Averous J., Fonseca B.D., and Proud C.G. Regulation of cyclin D1 expression by mTORC1 signaling requires eukaryotic initiation factor 4E-binding protein 1. Oncogene 27 (2007) 1106-1113
-
(2007)
Oncogene
, vol.27
, pp. 1106-1113
-
-
Averous, J.1
Fonseca, B.D.2
Proud, C.G.3
-
4
-
-
0037026596
-
Identification of a novel stress-responsive gene Hi95 involved in regulation of cell viability
-
Budanov A.V., Shoshani T., Faerman A., Zelin E., Kamer I., Kalinski H., Gorodin S., Fishman A., Chajut A., Einat P., et al. Identification of a novel stress-responsive gene Hi95 involved in regulation of cell viability. Oncogene 21 (2002) 6017-6031
-
(2002)
Oncogene
, vol.21
, pp. 6017-6031
-
-
Budanov, A.V.1
Shoshani, T.2
Faerman, A.3
Zelin, E.4
Kamer, I.5
Kalinski, H.6
Gorodin, S.7
Fishman, A.8
Chajut, A.9
Einat, P.10
-
5
-
-
2142815107
-
Regeneration of peroxiredoxins by p53-regulated sestrins, homologs of bacterial AhpD
-
Budanov A.V., Sablina A.A., Feinstein E., Koonin E.V., and Chumakov P.M. Regeneration of peroxiredoxins by p53-regulated sestrins, homologs of bacterial AhpD. Science 304 (2004) 596-600
-
(2004)
Science
, vol.304
, pp. 596-600
-
-
Budanov, A.V.1
Sablina, A.A.2
Feinstein, E.3
Koonin, E.V.4
Chumakov, P.M.5
-
6
-
-
0026541434
-
Zonation of cytochrome P450 isozyme expression and induction in rat liver
-
Buhler R., Lindros K.O., Nordling A., Johansson I., and Ingelman-Sundberg M. Zonation of cytochrome P450 isozyme expression and induction in rat liver. Eur. J. Biochem. 204 (1992) 407-412
-
(1992)
Eur. J. Biochem.
, vol.204
, pp. 407-412
-
-
Buhler, R.1
Lindros, K.O.2
Nordling, A.3
Johansson, I.4
Ingelman-Sundberg, M.5
-
7
-
-
0032539664
-
RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1
-
Burnett P.E., Barrow R.K., Cohen N.A., Snyder S.H., and Sabatini D.M. RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1. Proc. Natl. Acad. Sci. USA 95 (1998) 1432-1437
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 1432-1437
-
-
Burnett, P.E.1
Barrow, R.K.2
Cohen, N.A.3
Snyder, S.H.4
Sabatini, D.M.5
-
8
-
-
33750058023
-
Upstream of the mammalian target of rapamycin: Do all roads pass through mTOR?
-
Corradetti M.N., and Guan K.L. Upstream of the mammalian target of rapamycin: Do all roads pass through mTOR?. Oncogene 25 (2006) 6347-6360
-
(2006)
Oncogene
, vol.25
, pp. 6347-6360
-
-
Corradetti, M.N.1
Guan, K.L.2
-
9
-
-
20144362478
-
The solution structure of the FATC domain of the protein kinase target of rapamycin suggests a role for redox-dependent structural and cellular stability
-
Dames S.A., Mulet J.M., Rathgeb-Szabo K., Hall M.N., and Grzesiek S. The solution structure of the FATC domain of the protein kinase target of rapamycin suggests a role for redox-dependent structural and cellular stability. J. Biol. Chem. 280 (2005) 20558-20564
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 20558-20564
-
-
Dames, S.A.1
Mulet, J.M.2
Rathgeb-Szabo, K.3
Hall, M.N.4
Grzesiek, S.5
-
10
-
-
0033604521
-
Ribosomal S6 kinase signaling and the control of translation
-
Dufner A., and Thomas G. Ribosomal S6 kinase signaling and the control of translation. Exp. Cell Res. 253 (1999) 100-109
-
(1999)
Exp. Cell Res.
, vol.253
, pp. 100-109
-
-
Dufner, A.1
Thomas, G.2
-
11
-
-
20444363122
-
The coordinate regulation of the p53 and mTOR pathways in cells
-
Feng Z., Zhang H., Levine A.J., and Jin S. The coordinate regulation of the p53 and mTOR pathways in cells. Proc. Natl. Acad. Sci. USA 102 (2005) 8204-8209
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 8204-8209
-
-
Feng, Z.1
Zhang, H.2
Levine, A.J.3
Jin, S.4
-
12
-
-
34248194200
-
The regulation of AMPK {beta}1, TSC2, and PTEN expression by p53: Stress, cell and tissue dpecificity, and the role of these gene products in modulating the IGF-1-AKT-mTOR pathways
-
Feng Z., Hu W., de Stanchina E., Teresky A.K., Jin S., Lowe S., and Levine A.J. The regulation of AMPK {beta}1, TSC2, and PTEN expression by p53: Stress, cell and tissue dpecificity, and the role of these gene products in modulating the IGF-1-AKT-mTOR pathways. Cancer Res. 67 (2007) 3043-3053
-
(2007)
Cancer Res.
, vol.67
, pp. 3043-3053
-
-
Feng, Z.1
Hu, W.2
de Stanchina, E.3
Teresky, A.K.4
Jin, S.5
Lowe, S.6
Levine, A.J.7
-
13
-
-
2342545519
-
Target of rapamycin (TOR): An integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression
-
Fingar D.C., and Blenis J. Target of rapamycin (TOR): An integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression. Oncogene 23 (2004) 3151-3171
-
(2004)
Oncogene
, vol.23
, pp. 3151-3171
-
-
Fingar, D.C.1
Blenis, J.2
-
14
-
-
0345732640
-
mTOR controls cell cycle progression through its cell growth effectors S6K1 and 4E-BP1/eukaryotic translation initiation factor 4E
-
Fingar D.C., Richardson C.J., Tee A.R., Cheatham L., Tsou C., and Blenis J. mTOR controls cell cycle progression through its cell growth effectors S6K1 and 4E-BP1/eukaryotic translation initiation factor 4E. Mol. Cell. Biol. 24 (2004) 200-216
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 200-216
-
-
Fingar, D.C.1
Richardson, C.J.2
Tee, A.R.3
Cheatham, L.4
Tsou, C.5
Blenis, J.6
-
15
-
-
0028030882
-
MDM2 gene amplification and transcript levels in human sarcomas: Relationship to TP53 gene status
-
Florenes V.A., Maelandsmo G.M., Forus A., Andreassen A., Myklebost O., and Fodstad O. MDM2 gene amplification and transcript levels in human sarcomas: Relationship to TP53 gene status. J. Natl. Cancer Inst. 86 (1994) 1297-1302
-
(1994)
J. Natl. Cancer Inst.
, vol.86
, pp. 1297-1302
-
-
Florenes, V.A.1
Maelandsmo, G.M.2
Forus, A.3
Andreassen, A.4
Myklebost, O.5
Fodstad, O.6
-
16
-
-
0038433304
-
Insulin activation of Rheb, a mediator of mTOR/S6K/4E-BP signaling, is inhibited by TSC1 and 2
-
Garami A., Zwartkruis F.J., Nobukuni T., Joaquin M., Roccio M., Stocker H., Kozma S.C., Hafen E., Bos J.L., and Thomas G. Insulin activation of Rheb, a mediator of mTOR/S6K/4E-BP signaling, is inhibited by TSC1 and 2. Mol. Cell 11 (2003) 1457-1466
-
(2003)
Mol. Cell
, vol.11
, pp. 1457-1466
-
-
Garami, A.1
Zwartkruis, F.J.2
Nobukuni, T.3
Joaquin, M.4
Roccio, M.5
Stocker, H.6
Kozma, S.C.7
Hafen, E.8
Bos, J.L.9
Thomas, G.10
-
17
-
-
34250635347
-
PKC-mediated down-regulation of cyclin D1 involves activation of the translational repressor 4E-BP1 via a PI3K/Akt-independent, PP2A-dependent mechanism in intestinal epithelial cells
-
Guan L., Song K., Pysz M.A., Curry K.J., Hizli A.A., Danielpour D., Black A.R., and Black J.D. PKC-mediated down-regulation of cyclin D1 involves activation of the translational repressor 4E-BP1 via a PI3K/Akt-independent, PP2A-dependent mechanism in intestinal epithelial cells. J. Biol. Chem. 282 (2007) 14213-14225
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 14213-14225
-
-
Guan, L.1
Song, K.2
Pysz, M.A.3
Curry, K.J.4
Hizli, A.A.5
Danielpour, D.6
Black, A.R.7
Black, J.D.8
-
18
-
-
23144467910
-
An expanding role for mTOR in cancer
-
Guertin D.A., and Sabatini D.M. An expanding role for mTOR in cancer. Trends Mol. Med. 11 (2005) 353-361
-
(2005)
Trends Mol. Med.
, vol.11
, pp. 353-361
-
-
Guertin, D.A.1
Sabatini, D.M.2
-
19
-
-
34347220473
-
Defining the Role of mTOR in Cancer
-
Guertin D.A., and Sabatini D.M. Defining the Role of mTOR in Cancer. Cancer Cell 12 (2007) 9-22
-
(2007)
Cancer Cell
, vol.12
, pp. 9-22
-
-
Guertin, D.A.1
Sabatini, D.M.2
-
20
-
-
4043171462
-
Upstream and downstream of mTOR
-
Hay N., and Sonenberg N. Upstream and downstream of mTOR. Genes Dev. 18 (2004) 1926-1945
-
(2004)
Genes Dev.
, vol.18
, pp. 1926-1945
-
-
Hay, N.1
Sonenberg, N.2
-
21
-
-
0037043851
-
p53 activation results in rapid dephosphorylation of the eIF4E-binding protein 4E-BP1, inhibition of ribosomal protein S6 kinase and inhibition of translation initiation
-
Horton L.E., Bushell M., Barth-Baus D., Tilleray V.J., Clemens M.J., and Hensold J.O. p53 activation results in rapid dephosphorylation of the eIF4E-binding protein 4E-BP1, inhibition of ribosomal protein S6 kinase and inhibition of translation initiation. Oncogene 21 (2002) 5325-5334
-
(2002)
Oncogene
, vol.21
, pp. 5325-5334
-
-
Horton, L.E.1
Bushell, M.2
Barth-Baus, D.3
Tilleray, V.J.4
Clemens, M.J.5
Hensold, J.O.6
-
22
-
-
0345167800
-
TSC2 mediates cellular energy response to control cell growth and survival
-
Inoki K., Zhu T., and Guan K.L. TSC2 mediates cellular energy response to control cell growth and survival. Cell 115 (2003) 577-590
-
(2003)
Cell
, vol.115
, pp. 577-590
-
-
Inoki, K.1
Zhu, T.2
Guan, K.L.3
-
23
-
-
0043127125
-
Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling
-
Inoki K., Li Y., Xu T., and Guan K.L. Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling. Genes Dev. 17 (2003) 1829-1834
-
(2003)
Genes Dev.
, vol.17
, pp. 1829-1834
-
-
Inoki, K.1
Li, Y.2
Xu, T.3
Guan, K.L.4
-
24
-
-
0035734285
-
Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer
-
Jonkers J., Meuwissen R., van der Gulden H., Peterse H., van der Valk M., and Berns A. Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer. Nat. Genet. 29 (2001) 418-425
-
(2001)
Nat. Genet.
, vol.29
, pp. 418-425
-
-
Jonkers, J.1
Meuwissen, R.2
van der Gulden, H.3
Peterse, H.4
van der Valk, M.5
Berns, A.6
-
25
-
-
27744588780
-
Tuberous sclerosis: A GAP at the crossroads of multiple signaling pathways
-
Kwiatkowski D.J., and Manning B.D. Tuberous sclerosis: A GAP at the crossroads of multiple signaling pathways. Hum. Mol. Genet. 14 Spec No. 2 (2005) R251-R258
-
(2005)
Hum. Mol. Genet.
, vol.14 Spec 2
-
-
Kwiatkowski, D.J.1
Manning, B.D.2
-
26
-
-
0030941458
-
p53, the cellular gatekeeper for growth and division
-
Levine A.J. p53, the cellular gatekeeper for growth and division. Cell 88 (1997) 323-331
-
(1997)
Cell
, vol.88
, pp. 323-331
-
-
Levine, A.J.1
-
27
-
-
32044435126
-
Coordination and communication between the p53 and IGF-1-AKT-TOR signal transduction pathways
-
Levine A.J., Feng Z., Mak T.W., You H., and Jin S. Coordination and communication between the p53 and IGF-1-AKT-TOR signal transduction pathways. Genes Dev. 20 (2006) 267-275
-
(2006)
Genes Dev.
, vol.20
, pp. 267-275
-
-
Levine, A.J.1
Feng, Z.2
Mak, T.W.3
You, H.4
Jin, S.5
-
28
-
-
2342584183
-
eIF4E-from translation to transformation
-
Mamane Y., Petroulakis E., Rong L., Yoshida K., Ler L.W., and Sonenberg N. eIF4E-from translation to transformation. Oncogene 23 (2004) 3172-3179
-
(2004)
Oncogene
, vol.23
, pp. 3172-3179
-
-
Mamane, Y.1
Petroulakis, E.2
Rong, L.3
Yoshida, K.4
Ler, L.W.5
Sonenberg, N.6
-
29
-
-
33745213627
-
AMPK and cell proliferation-AMPK as a therapeutic target for atherosclerosis and cancer
-
Motoshima H., Goldstein B.J., Igata M., and Araki E. AMPK and cell proliferation-AMPK as a therapeutic target for atherosclerosis and cancer. J. Physiol. 574 (2006) 63-71
-
(2006)
J. Physiol.
, vol.574
, pp. 63-71
-
-
Motoshima, H.1
Goldstein, B.J.2
Igata, M.3
Araki, E.4
-
30
-
-
0038281228
-
PA26 is a candidate gene for heterotaxia in humans: Identification of a novel PA26-related gene family in human and mouse
-
Peeters H., Debeer P., Bairoch A., Wilquet V., Huysmans C., Parthoens E., Fryns J.P., Gewillig M., Nakamura Y., Niikawa N., et al. PA26 is a candidate gene for heterotaxia in humans: Identification of a novel PA26-related gene family in human and mouse. Hum. Genet. 112 (2003) 573-580
-
(2003)
Hum. Genet.
, vol.112
, pp. 573-580
-
-
Peeters, H.1
Debeer, P.2
Bairoch, A.3
Wilquet, V.4
Huysmans, C.5
Parthoens, E.6
Fryns, J.P.7
Gewillig, M.8
Nakamura, Y.9
Niikawa, N.10
-
31
-
-
11144356304
-
S6K1(-/-)/S6K2(-/-) mice exhibit perinatal lethality and rapamycin-sensitive 5′-terminal oligopyrimidine mRNA translation and reveal a mitogen-activated protein kinase-dependent S6 kinase pathway
-
Pende M., Um S.H., Mieulet V., Sticker M., Goss V.L., Mestan J., Mueller M., Fumagalli S., Kozma S.C., and Thomas G. S6K1(-/-)/S6K2(-/-) mice exhibit perinatal lethality and rapamycin-sensitive 5′-terminal oligopyrimidine mRNA translation and reveal a mitogen-activated protein kinase-dependent S6 kinase pathway. Mol. Cell. Biol. 24 (2004) 3112-3124
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 3112-3124
-
-
Pende, M.1
Um, S.H.2
Mieulet, V.3
Sticker, M.4
Goss, V.L.5
Mestan, J.6
Mueller, M.7
Fumagalli, S.8
Kozma, S.C.9
Thomas, G.10
-
32
-
-
0032898369
-
Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic beta cell-specific gene knock-outs using Cre recombinase
-
Postic C., Shiota M., Niswender K.D., Jetton T.L., Chen Y., Moates J.M., Shelton K.D., Lindner J., Cherrington A.D., and Magnuson M.A. Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic beta cell-specific gene knock-outs using Cre recombinase. J. Biol. Chem. 274 (1999) 305-315
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 305-315
-
-
Postic, C.1
Shiota, M.2
Niswender, K.D.3
Jetton, T.L.4
Chen, Y.5
Moates, J.M.6
Shelton, K.D.7
Lindner, J.8
Cherrington, A.D.9
Magnuson, M.A.10
-
33
-
-
0033046644
-
Loss of heterozygosity at chromosome 1p in different solid human tumours: association with survival
-
Ragnarsson G., Eiriksdottir G., Johannsdottir J.T., Jonasson J.G., Egilsson V., and Ingvarsson S. Loss of heterozygosity at chromosome 1p in different solid human tumours: association with survival. Br. J. Cancer 79 (1999) 1468-1474
-
(1999)
Br. J. Cancer
, vol.79
, pp. 1468-1474
-
-
Ragnarsson, G.1
Eiriksdottir, G.2
Johannsdottir, J.T.3
Jonasson, J.G.4
Egilsson, V.5
Ingvarsson, S.6
-
34
-
-
13444259647
-
Regulation of cap-dependent translation by eIF4E inhibitory proteins
-
Richter J.D., and Sonenberg N. Regulation of cap-dependent translation by eIF4E inhibitory proteins. Nature 433 (2005) 477-480
-
(2005)
Nature
, vol.433
, pp. 477-480
-
-
Richter, J.D.1
Sonenberg, N.2
-
35
-
-
33747819801
-
mTOR and cancer: Insights into a complex relationship
-
Sabatini D.M. mTOR and cancer: Insights into a complex relationship. Nat. Rev. Cancer 6 (2006) 729-734
-
(2006)
Nat. Rev. Cancer
, vol.6
, pp. 729-734
-
-
Sabatini, D.M.1
-
36
-
-
28644447272
-
The antioxidant function of the p53 tumor suppressor
-
Sablina A.A., Budanov A.V., Ilyinskaya G.V., Agapova L.S., Kravchenko J.E., and Chumakov P.M. The antioxidant function of the p53 tumor suppressor. Nat. Med. 11 (2005) 1306-1313
-
(2005)
Nat. Med.
, vol.11
, pp. 1306-1313
-
-
Sablina, A.A.1
Budanov, A.V.2
Ilyinskaya, G.V.3
Agapova, L.S.4
Kravchenko, J.E.5
Chumakov, P.M.6
-
37
-
-
28244469041
-
Redox regulation of the nutrient-sensitive raptor-mTOR pathway and complex
-
Sarbassov D.D., and Sabatini D.M. Redox regulation of the nutrient-sensitive raptor-mTOR pathway and complex. J. Biol. Chem. 280 (2005) 39505-39509
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 39505-39509
-
-
Sarbassov, D.D.1
Sabatini, D.M.2
-
38
-
-
3342895823
-
Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton
-
Sarbassov D.D., Ali S.M., Kim D.H., Guertin D.A., Latek R.R., Erdjument-Bromage H., Tempst P., and Sabatini D.M. Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton. Curr. Biol. 14 (2004) 1296-1302
-
(2004)
Curr. Biol.
, vol.14
, pp. 1296-1302
-
-
Sarbassov, D.D.1
Ali, S.M.2
Kim, D.H.3
Guertin, D.A.4
Latek, R.R.5
Erdjument-Bromage, H.6
Tempst, P.7
Sabatini, D.M.8
-
39
-
-
33646023695
-
Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB
-
Sarbassov D.D., Ali S.M., Sengupta S., Sheen J.H., Hsu P.P., Bagley A.F., Markhard A.L., and Sabatini D.M. Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB. Mol. Cell 22 (2006) 159-168
-
(2006)
Mol. Cell
, vol.22
, pp. 159-168
-
-
Sarbassov, D.D.1
Ali, S.M.2
Sengupta, S.3
Sheen, J.H.4
Hsu, P.P.5
Bagley, A.F.6
Markhard, A.L.7
Sabatini, D.M.8
-
41
-
-
20544451118
-
The mammalian target of rapamycin signaling network and gene regulation
-
Soliman G.A. The mammalian target of rapamycin signaling network and gene regulation. Curr. Opin. Lipidol. 16 (2005) 317-323
-
(2005)
Curr. Opin. Lipidol.
, vol.16
, pp. 317-323
-
-
Soliman, G.A.1
-
42
-
-
0042701991
-
Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb
-
Tee A.R., Manning B.D., Roux P.P., Cantley L.C., and Blenis J. Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb. Curr. Biol. 13 (2003) 1259-1268
-
(2003)
Curr. Biol.
, vol.13
, pp. 1259-1268
-
-
Tee, A.R.1
Manning, B.D.2
Roux, P.P.3
Cantley, L.C.4
Blenis, J.5
-
43
-
-
30644468118
-
mTOR and cancer: Reason for dancing at the crossroads?
-
Thomas G.V. mTOR and cancer: Reason for dancing at the crossroads?. Curr. Opin. Genet. Dev. 16 (2006) 78-84
-
(2006)
Curr. Opin. Genet. Dev.
, vol.16
, pp. 78-84
-
-
Thomas, G.V.1
-
44
-
-
10744221485
-
In vivo activation of the p53 pathway by small-molecule antagonists of MDM2
-
Vassilev L.T., Vu B.T., Graves B., Carvajal D., Podlaski F., Filipovic Z., Kong N., Kammlott U., Lukacs C., Klein C., et al. In vivo activation of the p53 pathway by small-molecule antagonists of MDM2. Science 303 (2004) 844-848
-
(2004)
Science
, vol.303
, pp. 844-848
-
-
Vassilev, L.T.1
Vu, B.T.2
Graves, B.3
Carvajal, D.4
Podlaski, F.5
Filipovic, Z.6
Kong, N.7
Kammlott, U.8
Lukacs, C.9
Klein, C.10
-
45
-
-
0033531264
-
PA26, a novel target of the p53 tumor suppressor and member of the GADD family of DNA damage and growth arrest inducible genes
-
Velasco-Miguel S., Buckbinder L., Jean P., Gelbert L., Talbott R., Laidlaw J., Seizinger B., and Kley N. PA26, a novel target of the p53 tumor suppressor and member of the GADD family of DNA damage and growth arrest inducible genes. Oncogene 18 (1999) 127-137
-
(1999)
Oncogene
, vol.18
, pp. 127-137
-
-
Velasco-Miguel, S.1
Buckbinder, L.2
Jean, P.3
Gelbert, L.4
Talbott, R.5
Laidlaw, J.6
Seizinger, B.7
Kley, N.8
-
46
-
-
0029780653
-
N-nitrosodiethylamine mechanistic data and risk assessment: bioactivation, DNA-adduct formation, mutagenicity, and tumor initiation
-
Verna L., Whysner J., and Williams G.M. N-nitrosodiethylamine mechanistic data and risk assessment: bioactivation, DNA-adduct formation, mutagenicity, and tumor initiation. Pharmacol. Ther. 71 (1996) 57-81
-
(1996)
Pharmacol. Ther.
, vol.71
, pp. 57-81
-
-
Verna, L.1
Whysner, J.2
Williams, G.M.3
-
48
-
-
32044465506
-
TOR signaling in growth and metabolism
-
Wullschleger S., Loewith R., and Hall M.N. TOR signaling in growth and metabolism. Cell 124 (2006) 471-484
-
(2006)
Cell
, vol.124
, pp. 471-484
-
-
Wullschleger, S.1
Loewith, R.2
Hall, M.N.3
-
49
-
-
34547907805
-
Expanding mTOR signaling
-
Yang Q., and Guan K.L. Expanding mTOR signaling. Cell Res. 17 (2007) 666-681
-
(2007)
Cell Res.
, vol.17
, pp. 666-681
-
-
Yang, Q.1
Guan, K.L.2
-
50
-
-
0034773404
-
Role of AMP-activated protein kinase in mechanism of metformin action
-
Zhou G., Myers R., Li Y., Chen Y., Shen X., Fenyk-Melody J., Wu M., Ventre J., Doebber T., Fujii N., et al. Role of AMP-activated protein kinase in mechanism of metformin action. J. Clin. Invest. 108 (2001) 1167-1174
-
(2001)
J. Clin. Invest.
, vol.108
, pp. 1167-1174
-
-
Zhou, G.1
Myers, R.2
Li, Y.3
Chen, Y.4
Shen, X.5
Fenyk-Melody, J.6
Wu, M.7
Ventre, J.8
Doebber, T.9
Fujii, N.10
|