The PERK/ATF4/LAMP3-arm of the unfolded protein response affects radioresistance by interfering with the DNA damage response

Radiotherapy and Oncology

Volumn 108, Issue 3, 2013, Pages 415-421

  Nagelkerke, Anika ^a   Bussink, Johan ^a   Van Der Kogel, Albert J ^a   Sweep, Fred C G J ^a   Span, Paul N ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Breast cancer; LAMP3; Radiation; Resistance; UPR

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; BAFILOMYCIN A1; CHLOROQUINE; DENDRITIC CELL LYSOSOME ASSOCIATED MEMBRANE PROTEIN; HISTONE H2AX; MESSENGER RNA; PERK PROTEIN; PROTEIN KINASE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ARTICLE; AUTOPHAGY; BREAST CANCER; CANCER CELL; CLONOGENIC ASSAY; CONTROLLED STUDY; DNA DAMAGE; GENE ACTIVATION; IMMUNOCYTOCHEMISTRY; IRRADIATION; PRIORITY JOURNAL; RADIATION ATTENUATION; RADIATION RESPONSE; RADIOSENSITIVITY; UNFOLDED PROTEIN RESPONSE; WESTERN BLOTTING;

BREAST CANCER; LAMP3; RADIATION; RESISTANCE; UPR;

ACTIVATING TRANSCRIPTION FACTOR 4; AUTOPHAGY; BREAST NEOPLASMS; CELL LINE, TUMOR; DNA DAMAGE; EIF-2 KINASE; FEMALE; HISTONES; HUMANS; LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEINS; NEOPLASM PROTEINS; PROTEIN PHOSPHATASE 1; RADIATION TOLERANCE; UNFOLDED PROTEIN RESPONSE;

EID: 84887024055     PISSN: 01678140     EISSN: 18790887     Source Type: Journal    
DOI: 10.1016/j.radonc.2013.06.037     Document Type: Article

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