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Volumn 153, Issue 5, 2013, Pages 1064-

XThe eEF2 kinase confers resistance to nutrient deprivation by blocking translation elongation

(39)  Leprivier, Gabriel a   Remke, Marc b,c,d   Rotblat, Barak a   Dubuc, Adrian b,c   Mateo, Abigail Rachele F c,e   Kool, Marcel d   Agnihotri, Sameer b   El Naggar, Amal a   Yu, Bin e   Prakash Somasekharan, Syam a   Faubert, Brandon f   Bridon, Gaëlle f   Tognon, Cristina E a   Mathers, Joan a   Thomas, Ryan a   Li, Amy a   Barokas, Adi a   Kwok, Brian a   Bowden, Mary g   Smith, Stephanie g   more..


Author keywords

[No Author keywords available]

Indexed keywords

ELONGATION FACTOR 2 KINASE; TRANSCRIPTION FACTOR ELK 1;

EID: 84878271546     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2013.04.055     Document Type: Article
Times cited : (331)

References (52)
  • 1
    • 64249139132 scopus 로고    scopus 로고
    • RNA Pol II accumulates at promoters of growth genes during developmental arrest
    • L.R. Baugh, J. Demodena, and P.W. Sternberg RNA Pol II accumulates at promoters of growth genes during developmental arrest Science 324 2009 92 94
    • (2009) Science , vol.324 , pp. 92-94
    • Baugh, L.R.1    Demodena, J.2    Sternberg, P.W.3
  • 3
    • 0016063911 scopus 로고
    • The genetics of Caenorhabditis elegans
    • S. Brenner The genetics of Caenorhabditis elegans Genetics 77 1974 71 94
    • (1974) Genetics , vol.77 , pp. 71-94
    • Brenner, S.1
  • 4
    • 0028802746 scopus 로고
    • A hierarchy of ATP-consuming processes in mammalian cells
    • F. Buttgereit, and M.D. Brand A hierarchy of ATP-consuming processes in mammalian cells Biochem. J. 312 1995 163 167
    • (1995) Biochem. J. , vol.312 , pp. 163-167
    • Buttgereit, F.1    Brand, M.D.2
  • 5
    • 20544449673 scopus 로고    scopus 로고
    • The glucose dependence of Akt-transformed cells can be reversed by pharmacologic activation of fatty acid beta-oxidation
    • M. Buzzai, D.E. Bauer, R.G. Jones, R.J. Deberardinis, G. Hatzivassiliou, R.L. Elstrom, and C.B. Thompson The glucose dependence of Akt-transformed cells can be reversed by pharmacologic activation of fatty acid beta-oxidation Oncogene 24 2005 4165 4173
    • (2005) Oncogene , vol.24 , pp. 4165-4173
    • Buzzai, M.1    Bauer, D.E.2    Jones, R.G.3    Deberardinis, R.J.4    Hatzivassiliou, G.5    Elstrom, R.L.6    Thompson, C.B.7
  • 6
    • 0025003542 scopus 로고
    • Functional properties of phosphorylated elongation factor 2
    • U. Carlberg, A. Nilsson, and O. Nygård Functional properties of phosphorylated elongation factor 2 Eur. J. Biochem. 191 1990 639 645
    • (1990) Eur. J. Biochem. , vol.191 , pp. 639-645
    • Carlberg, U.1    Nilsson, A.2    Nygård, O.3
  • 9
    • 77952562382 scopus 로고    scopus 로고
    • Glucose addiction of TSC null cells is caused by failed mTORC1-dependent balancing of metabolic demand with supply
    • A.Y. Choo, S.G. Kim, M.G. Vander Heiden, S.J. Mahoney, H. Vu, S.O. Yoon, L.C. Cantley, and J. Blenis Glucose addiction of TSC null cells is caused by failed mTORC1-dependent balancing of metabolic demand with supply Mol. Cell 38 2010 487 499
    • (2010) Mol. Cell , vol.38 , pp. 487-499
    • Choo, A.Y.1    Kim, S.G.2    Vander Heiden, M.G.3    Mahoney, S.J.4    Vu, H.5    Yoon, S.O.6    Cantley, L.C.7    Blenis, J.8
  • 11
    • 0014966082 scopus 로고
    • Regulation of protein synthesis in mammalian cells. II. Inhibition of protein synthesis at the level of initiation during mitosis
    • H. Fan, and S. Penman Regulation of protein synthesis in mammalian cells. II. Inhibition of protein synthesis at the level of initiation during mitosis J. Mol. Biol. 50 1970 655 670
    • (1970) J. Mol. Biol. , vol.50 , pp. 655-670
    • Fan, H.1    Penman, S.2
  • 12
    • 80053035284 scopus 로고    scopus 로고
    • AMP-activated protein kinase: An energy sensor that regulates all aspects of cell function
    • D.G. Hardie AMP-activated protein kinase: an energy sensor that regulates all aspects of cell function Genes Dev. 25 2011 1895 1908
    • (2011) Genes Dev. , vol.25 , pp. 1895-1908
    • Hardie, D.G.1
  • 13
    • 4043171462 scopus 로고    scopus 로고
    • Upstream and downstream of mTOR
    • N. Hay, and N. Sonenberg Upstream and downstream of mTOR Genes Dev. 18 2004 1926 1945
    • (2004) Genes Dev. , vol.18 , pp. 1926-1945
    • Hay, N.1    Sonenberg, N.2
  • 14
    • 0345167800 scopus 로고    scopus 로고
    • TSC2 mediates cellular energy response to control cell growth and survival
    • K. Inoki, T. Zhu, and K.L. Guan TSC2 mediates cellular energy response to control cell growth and survival Cell 115 2003 577 590
    • (2003) Cell , vol.115 , pp. 577-590
    • Inoki, K.1    Zhu, T.2    Guan, K.L.3
  • 15
    • 0036845620 scopus 로고    scopus 로고
    • Patterns of gene expression in atrophying skeletal muscles: Response to food deprivation
    • R.T. Jagoe, S.H. Lecker, M. Gomes, and A.L. Goldberg Patterns of gene expression in atrophying skeletal muscles: response to food deprivation FASEB J. 16 2002 1697 1712
    • (2002) FASEB J. , vol.16 , pp. 1697-1712
    • Jagoe, R.T.1    Lecker, S.H.2    Gomes, M.3    Goldberg, A.L.4
  • 16
    • 84863763440 scopus 로고    scopus 로고
    • AMPK regulates NADPH homeostasis to promote tumour cell survival during energy stress
    • S.M. Jeon, N.S. Chandel, and N. Hay AMPK regulates NADPH homeostasis to promote tumour cell survival during energy stress Nature 485 2012 661 665
    • (2012) Nature , vol.485 , pp. 661-665
    • Jeon, S.M.1    Chandel, N.S.2    Hay, N.3
  • 17
    • 0021686137 scopus 로고
    • Arresting development arrests aging in the nematode Caenorhabditis elegans
    • T.E. Johnson, D.H. Mitchell, S. Kline, R. Kemal, and J. Foy Arresting development arrests aging in the nematode Caenorhabditis elegans Mech. Ageing Dev. 28 1984 23 40
    • (1984) Mech. Ageing Dev. , vol.28 , pp. 23-40
    • Johnson, T.E.1    Mitchell, D.H.2    Kline, S.3    Kemal, R.4    Foy, J.5
  • 18
    • 61849135453 scopus 로고    scopus 로고
    • Tumor suppressors and cell metabolism: A recipe for cancer growth
    • R.G. Jones, and C.B. Thompson Tumor suppressors and cell metabolism: a recipe for cancer growth Genes Dev. 23 2009 537 548
    • (2009) Genes Dev. , vol.23 , pp. 537-548
    • Jones, R.G.1    Thompson, C.B.2
  • 19
    • 64749108996 scopus 로고    scopus 로고
    • Tumours with PI3K activation are resistant to dietary restriction
    • N.Y. Kalaany, and D.M. Sabatini Tumours with PI3K activation are resistant to dietary restriction Nature 458 2009 725 731
    • (2009) Nature , vol.458 , pp. 725-731
    • Kalaany, N.Y.1    Sabatini, D.M.2
  • 22
    • 36348996412 scopus 로고    scopus 로고
    • Origin and principles of translational control
    • M.B. Mathews, N. Sonenberg, J.W.B. Hershey, Cold Spring Harbor Laboratory Press Cold Spring Harbor, NY
    • M.B. Mathews, N. Sonenberg, and J.W.B. Hershey Origin and principles of translational control M.B. Mathews, N. Sonenberg, J.W.B. Hershey, Translational Control in Biology and Medicine 2007 Cold Spring Harbor Laboratory Press Cold Spring Harbor, NY 1 40
    • (2007) Translational Control in Biology and Medicine , pp. 1-40
    • Mathews, M.B.1    Sonenberg, N.2    Hershey, J.W.B.3
  • 24
    • 62549151252 scopus 로고    scopus 로고
    • Why are tumour blood vessels abnormal and why is it important to know?
    • J.A. Nagy, S.H. Chang, A.M. Dvorak, and H.F. Dvorak Why are tumour blood vessels abnormal and why is it important to know? Br. J. Cancer 100 2009 865 869
    • (2009) Br. J. Cancer , vol.100 , pp. 865-869
    • Nagy, J.A.1    Chang, S.H.2    Dvorak, A.M.3    Dvorak, H.F.4
  • 28
    • 34247118887 scopus 로고    scopus 로고
    • Signalling to translation: How signal transduction pathways control the protein synthetic machinery
    • C.G. Proud Signalling to translation: how signal transduction pathways control the protein synthetic machinery Biochem. J. 403 2007 217 234
    • (2007) Biochem. J. , vol.403 , pp. 217-234
    • Proud, C.G.1
  • 29
    • 0023884601 scopus 로고
    • Phosphorylation of elongation factor 2 by EF-2 kinase affects rate of translation
    • A.G. Ryazanov, E.A. Shestakova, and P.G. Natapov Phosphorylation of elongation factor 2 by EF-2 kinase affects rate of translation Nature 334 1988 170 173
    • (1988) Nature , vol.334 , pp. 170-173
    • Ryazanov, A.G.1    Shestakova, E.A.2    Natapov, P.G.3
  • 30
    • 0037072531 scopus 로고    scopus 로고
    • Transient up-regulation of elongation factor-2 kinase (Ca2+/calmodulin-dependent protein kinase III) messenger RNA in developing mouse brain
    • H. Sakagami, H. Nishimura, R. Saito, and H. Kondo Transient up-regulation of elongation factor-2 kinase (Ca2+/calmodulin-dependent protein kinase III) messenger RNA in developing mouse brain Neurosci. Lett. 330 2002 41 44
    • (2002) Neurosci. Lett. , vol.330 , pp. 41-44
    • Sakagami, H.1    Nishimura, H.2    Saito, R.3    Kondo, H.4
  • 31
  • 33
    • 23944525416 scopus 로고    scopus 로고
    • 4E-BP functions as a metabolic brake used under stress conditions but not during normal growth
    • A.A. Teleman, Y.W. Chen, and S.M. Cohen 4E-BP functions as a metabolic brake used under stress conditions but not during normal growth Genes Dev. 19 2005 1844 1848
    • (2005) Genes Dev. , vol.19 , pp. 1844-1848
    • Teleman, A.A.1    Chen, Y.W.2    Cohen, S.M.3
  • 35
    • 73649123907 scopus 로고    scopus 로고
    • Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1
    • Cancer Genome Atlas Research Network
    • R.G. Verhaak, K.A. Hoadley, E. Purdom, V. Wang, Y. Qi, M.D. Wilkerson, C.R. Miller, L. Ding, T. Golub, J.P. Mesirov Cancer Genome Atlas Research Network Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1 Cancer Cell 17 2010 98 110
    • (2010) Cancer Cell , vol.17 , pp. 98-110
    • Verhaak, R.G.1    Hoadley, K.A.2    Purdom, E.3    Wang, V.4    Qi, Y.5    Wilkerson, M.D.6    Miller, C.R.7    Ding, L.8    Golub, T.9    Mesirov, J.P.10
  • 36
    • 0035881470 scopus 로고    scopus 로고
    • Regulation of elongation factor 2 kinase by p90(RSK1) and p70 S6 kinase
    • X. Wang, W. Li, M. Williams, N. Terada, D.R. Alessi, and C.G. Proud Regulation of elongation factor 2 kinase by p90(RSK1) and p70 S6 kinase EMBO J. 20 2001 4370 4379
    • (2001) EMBO J. , vol.20 , pp. 4370-4379
    • Wang, X.1    Li, W.2    Williams, M.3    Terada, N.4    Alessi, D.R.5    Proud, C.G.6
  • 37
    • 33645531089 scopus 로고    scopus 로고
    • Elongation factor-2 kinase regulates autophagy in human glioblastoma cells
    • H. Wu, J.M. Yang, S. Jin, H. Zhang, and W.N. Hait Elongation factor-2 kinase regulates autophagy in human glioblastoma cells Cancer Res. 66 2006 3015 3023
    • (2006) Cancer Res. , vol.66 , pp. 3015-3023
    • Wu, H.1    Yang, J.M.2    Jin, S.3    Zhang, H.4    Hait, W.N.5
  • 42
    • 78650510609 scopus 로고    scopus 로고
    • MTOR: From growth signal integration to cancer, diabetes and ageing
    • R. Zoncu, A. Efeyan, and D.M. Sabatini mTOR: from growth signal integration to cancer, diabetes and ageing Nat. Rev. Mol. Cell Biol. 12 2011 21 35
    • (2011) Nat. Rev. Mol. Cell Biol. , vol.12 , pp. 21-35
    • Zoncu, R.1    Efeyan, A.2    Sabatini, D.M.3
  • 43
    • 54549108740 scopus 로고    scopus 로고
    • Comprehensive genomic characterization defines human glioblastoma genes and core pathways
    • Cancer Genome Atlas Research Network
    • Cancer Genome Atlas Research Network Comprehensive genomic characterization defines human glioblastoma genes and core pathways Nature 455 2008 1061 1068
    • (2008) Nature , vol.455 , pp. 1061-1068
  • 45
    • 65449141379 scopus 로고    scopus 로고
    • An upstream open reading frame regulates translation of GADD34 during cellular stresses that induce eIF2alpha phosphorylation
    • Y.Y. Lee, R.C. Cevallos, and E. Jan An upstream open reading frame regulates translation of GADD34 during cellular stresses that induce eIF2alpha phosphorylation J. Biol. Chem. 284 2009 6661 6673
    • (2009) J. Biol. Chem. , vol.284 , pp. 6661-6673
    • Lee, Y.Y.1    Cevallos, R.C.2    Jan, E.3
  • 46
    • 61349128532 scopus 로고    scopus 로고
    • Rembrandt: Helping personalized medicine become a reality through integrative translational research
    • S. Madhavan, J.C. Zenklusen, Y. Kotliarov, H. Sahni, H.A. Fine, and K. Buetow Rembrandt: helping personalized medicine become a reality through integrative translational research Mol. Cancer Res. 7 2009 157 167
    • (2009) Mol. Cancer Res. , vol.7 , pp. 157-167
    • Madhavan, S.1    Zenklusen, J.C.2    Kotliarov, Y.3    Sahni, H.4    Fine, H.A.5    Buetow, K.6
  • 47
    • 33644517220 scopus 로고    scopus 로고
    • The insulin-like growth factor i receptor is required for Akt activation and suppression of anoikis in cells transformed by the ETV6-NTRK3 chimeric tyrosine kinase
    • M.J. Martin, N. Melnyk, M. Pollard, M. Bowden, H. Leong, T.J. Podor, M. Gleave, and P.H. Sorensen The insulin-like growth factor I receptor is required for Akt activation and suppression of anoikis in cells transformed by the ETV6-NTRK3 chimeric tyrosine kinase Mol. Cell. Biol. 26 2006 1754 1769
    • (2006) Mol. Cell. Biol. , vol.26 , pp. 1754-1769
    • Martin, M.J.1    Melnyk, N.2    Pollard, M.3    Bowden, M.4    Leong, H.5    Podor, T.J.6    Gleave, M.7    Sorensen, P.H.8
  • 48
    • 0037158897 scopus 로고    scopus 로고
    • ETV6-NTRK3 transformation requires insulin-like growth factor 1 receptor signaling and is associated with constitutive IRS-1 tyrosine phosphorylation
    • K.B. Morrison, C.E. Tognon, M.J. Garnett, C. Deal, and P.H. Sorensen ETV6-NTRK3 transformation requires insulin-like growth factor 1 receptor signaling and is associated with constitutive IRS-1 tyrosine phosphorylation Oncogene 21 2002 5684 5695
    • (2002) Oncogene , vol.21 , pp. 5684-5695
    • Morrison, K.B.1    Tognon, C.E.2    Garnett, M.J.3    Deal, C.4    Sorensen, P.H.5
  • 52
    • 38449085292 scopus 로고    scopus 로고
    • Maintenance of C. elegans
    • T. Stiernagle Maintenance of C. elegans WormBook Feb. 11 2006 1 11
    • (2006) WormBook , vol.11 FEB. , pp. 1-11
    • Stiernagle, T.1


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