Translation of cellular inhibitor of apoptosis protein 1 (c-IAP1) mRNA is IRES mediated and regulated during cell stress

RNA

Volumn 10, Issue 3, 2004, Pages 469-481

  Van Eden, Marc E ^a   Byrd, Marshall P ^a   Sherrill, Kyle W ^a   Lloyd, Richard E ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Apoptosis; Inhibitor of apoptosis protein; Internal ribosome entry site; Translation

Indexed keywords

ARSENITE SODIUM; CASPASE; ETOPOSIDE; INHIBITOR OF APOPTOSIS PROTEIN; INHIBITOR OF APOPTOSIS PROTEIN 1; MESSENGER RNA; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; TUMOR NECROSIS FACTOR RECEPTOR; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 1; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 2; UNCLASSIFIED DRUG;

5' UNTRANSLATED REGION; APOPTOSIS; ARTICLE; CELL SPECIFICITY; CELL STRAIN HEPG2; CELL TYPE; CISTRON; CODON; CONTROLLED STUDY; ENZYME INHIBITION; GENE EXPRESSION REGULATION; GENE INSERTION; GENETIC TRANSFECTION; HELA CELL; HEPATITIS C VIRUS; HUMAN; HUMAN CELL; INTERNAL RIBOSOME ENTRY SITE; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYADENYLATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN SECONDARY STRUCTURE; PROTEIN STABILITY; REGULATORY MECHANISM; RETICULOCYTE LYSATE; RNA CAPPING; RNA TRANSLATION; STRESS; THERMOSTABILITY; TRANSLATION REGULATION;

BASE SEQUENCE; HELA CELLS; HUMANS; INHIBITOR OF APOPTOSIS PROTEINS; MOLECULAR SEQUENCE DATA; PROTEINS; RETICULOCYTES; RNA, MESSENGER; TRANSFECTION;

HEPATITIS C VIRUS; INSERTION SEQUENCES; ORYCTOLAGUS CUNICULUS;

EID: 1242273881     PISSN: 13558382     EISSN: None     Source Type: Journal    
DOI: 10.1261/rna.5156804     Document Type: Article

References (59)

1. Ali, N. and Siddiqui, A. 1995. Interaction of polypyrimidine tract-binding protein with the 5′ noncoding region of the hepatitis C virus RNA genome and its functional requirement in internal initiation of translation. J. Virol. 69: 6367-6375.
2. Blyn, L.B., Towner, J.S., Semler, B.L., and Ehrenfeld, E. 1997. Requirement of poly(rC) binding protein 2 for translation of poliovirus RNA. J. Virol. 71: 6243-6246.
3. Bovee, M.L., Lamphear, B.J., Rhoads, R.E., and Lloyd, R.E. 1998. Direct cleavage of eIF4G by poliovirus 2A protease is inefficient in vitro. Virology 245: 241-249.
4. Byrd, M.P., Zamora, M., and Lloyd, R.E. 2002. Generation of multiple isoforms of eukaryotic translation initiation factor 4GI by use of alternate translation initiation codons. Mol. Cell Biol. 22: 4499-4511.
5. Chen, C.Y.A., Xu, N., and Shyu, A.B. 1995. MRNA decay mediated by two distinct AU-rich elements from c-fos and granulocyte-macrophage colony-stimulating transcripts: Different deadenylation kinetics and uncoupling from translation. Mol. Cell Biol. 15: 5777-5788.
6. Deveraux, Q.L. and Reed, J.C. 1999. IAP family proteins-Suppressors of apoptosis. Genes & Dev. 13: 239-252.
7. Deveraux, Q.L., Takahashi, R., Salvesen, G.S., and Reed, J.C. 1997. X-linked IAP is a direct inhibitor of cell-death proteases. Nature 388: 300-304.
8. Ekedahl, J., Joseph, B., Grigoriev, M.Y., Muller, M., Magnusson, C., Lewensohn, R., and Zhivotovsky, B. 2002. Expression of inhibitor of apoptosis proteins in small- and non-small-cell lung carcinoma cells. Exp. Cell Res. 279: 277-290.
9. Ekert, P.G., Silke, J., and Vaux, D.L. 1999. Caspase inhibitors. Cell Death Differ. 6: 1081-1086.
10. Gale, M., Tan, S., and Katze, M.G. 2000. Translational control of viral gene expression in eukaryotes. Microbiol. Mol. Biol. Rev. 64: 239-280.
11. Hambidge, S.J. and Sarnow, P. 1992. Translational enhancement of the poliovirus 5′ noncoding region mediated by virus-encoded polypeptide 2A. Proc. Natl. Acad. Sci. 89: 10272-10276.
12. Hellen, C.U. and Sarnow, P. 2001. Internal ribosome entry sites in eukaryotic mRNA molecules. Genes & Dev. 15: 1593-1612.
13. Hellen, C.U., Witherell, G.W., Schmid, M., Shin, S.H., Pestova, T.V., Gil, A., and Wimmer, E. 1993. A cytoplasmic 57-kDa protein that is required for translation of picornavirus RNA by internal ribosomal entry is identical to the nuclear pyrimidine tract-binding protein. Proc. Natl. Acad. Sci. 90: 7642-7646.
14. Hengartner, M.O. 2000. The biochemistry of apoptosis. Nature 407: 770-776.
15. Henis-Korenblit, S., Shani, G., Sines, T., Marash, L., Shohat, G., and Kimchi, A. 2002. The caspases-cleaved DAP5 protein supports internal ribosome entry site-mediated translation of death proteins. Proc. Natl. Acad. Sci. 99: 5400-5405.
16. Hinds, M.G., Norton, R.S., Vaux, D.L., and Day, C.L. 1999. Solution structure of a baculoviral inhibitor of apoptosis (IAP) repeat. Nat. Struct. Biol. 6: 648-651.
17. Holcik, M. and Korneluk, R.G. 2000. Functional characterization of the X-linked inhibitor of apoptosis (XIAP) internal ribosome entry site element: Role of La autoantigen in XIAP translation. Mol. Cell Biol. 20: 4648-4657.
18. Holcik, M., Lefebvre, C., Yeh, C., Chow, T., and Korneluk, R.G. 1999. A new internal-ribosome-entry-site motif potentiates XIAP-mediated cytoprotection. Nat. Cell. Biol. 1: 190-192.
19. Holcik, M., Sonenberg, N., and Korneluk, R.G. 2000a. Internal ribosome initiation of translation and the control of cell death. Trends Genet. 16: 469-473.
20. Holcik, M., Yeh, C., Korneluk, R.G., and Chow, T. 2000b. Translational upregulation of apoptosis (XIAP) increases resistance to radiation induced cell death. Oncogene 19: 4174-4177.
21. Holcik, M., Gordon, B.W., and Korneluk, R.G. 2003. The internal ribosome entry site-mediated translation of antiapoptotic protein XIAP is modulated by the heterogeneous nuclear ribonucleoproteins C1 and C2. Mol. Cell Biol. 23: 280-288.
22. Honda, S., Kaneko, S., Matsushita, E., Kobayashi, K., Abell, G.A., and Lemon, S.M. 2000. Cell cycle regulation of Hepatitis C Virus internal ribosomal entry site-directed translation. Gastroenterology 118: 152-162.
23. Hu, S. and Yang, X. 2003. Cellular inhibitor of apoptosis 1 and 2 are ubiquitin ligases for the apoptosis inducer Smac/DIABLO. J. Biol. Chem. 278: 10055-10060.
24. Johannes, G., Carter, M.S., Eisen, M.B., Brown, P.O., and Sarnow, P. 1999. Identification of eukaryotic mRNAs that are translated at reduced cap binding complex eIF4F concentrations using a cDNA microarray. Proc. Natl. Acad. Sci. 96: 13118-13123.
25. Kozak, M. 1991. An analysis of vertebrate mRNA sequences: Intimations of translational control. J. Cell Biol. 115: 887-903.
26. -. 1999. Initiation of translation in prokaryotes and eukaryotes. Gene 234: 187-208.
27. -. 2001. New ways of initiating translation in eukaryotes? Mol. Cell Biol. 21: 1899-1907.
28. -. 2002. Pushing the limits of the scanning mechanism for initiation of translation. Gene 299: 1-34.
29. Kuyumcu-Martinez, N.M., Joachims, M., and Lloyd, R.E. 2002. Efficient cleavage of ribosome-associated poly(A)-binding protein by enterovirus 3C protease. J. Virol. 76: 2062-2074.
30. LaCasse, E.C., Baird, S., Korneluk, R.G., and MacKenzie, A.E. 1998. The inhibitors of apoptosis (IAPs) and their emerging role in cancer. Oncogene 17: 3247-3259.
31. Le, S.Y. and Maizel, J.V. 1997. A common RNA structural motif involved in the internal initiation of translation of cellular mRNAs. Nucleic Acids Res. 25: 362-369.
32. Li, X., Yang, Y., and Ashwell, J.D. 2002. TNF-RII and c-IAP1 mediate ubiquitination and degradation of TRAF2. Nature 416: 345-347.
33. Marissen, W.E. and Lloyd, R.E. 1998. Eukaryotic translation initiation factor 4G is targeted for proteolytic cleavage by caspase 3 during inhibition of translation in apoptotic cells. Mol. Cell Biol. 18: 7565-7574.
34. Marissen, W.E., Gradi, A., Sonenberg, N., and Lloyd, R.E. 2000a. Cleavage of eukaryotic translation initiation factor 4GII correlates with translation inhibition during apoptosis. Cell Death Differ. 12: 1234-1243.
35. Marissen, W.E., Guo, Y., Thomas, A.A., Matts, R.L., and Lloyd, R.E. 2000b. Identification of caspases 3-mediated cleavage and functional alteration of eukaryotic initiation factor 2α in apoptosis. J. Biol. Chem. 275: 9314-9323.
36. Meerovitch, K., Svitkin, Y.V., Lee, H.S., Lejbkowicz, F., Kenan, D.J., Chan, E.K., Agol, V.I., Keene, J.D., and Sonenberg, N. 1993. La autoantigen enhances and corrects aberrant translation of poliovirus RNA in reticulocyte lysate. J. Virol. 67: 3798-3807.
37. Morrish, B.C. and Rumsby, M.G. 2002. The 5′ untranslated region of protein kinase Cδ directs translation by an internal ribosome entry segment that is most active in densly growing cells and during apoptosis. Mol. Cell Biol. 22: 6089-6099.
38. Nicholson, D.W. 1999. Caspase structure, proteolytic substrates, and function during apoptotic cell death. Cell Death Differ. 6: 1028-1042.
39. Ochs, K., Saleh, L., Bassili, G., Sonntag, V.H., Zeller, A., and Niepmann, M. 2002. Interaction of translation initiation factor eIF4B with the poliovirus internal ribosome entry site. J. Virol. 76: 2113-2122.
40. Pestova, T.V., Kolupaeva, V.G., Lomakin, I.B., Pilipenko, E.V., Shatsky, I.N., Agol, V.I., and Hellen, C.U.T. 2001. Molecular mechanisms of translation initiation in eukaryotes. Proc. Natl. Acad. Sci. 98: 7029-7036.
41. Pudi, R., Abhiman, S., Srinivasan, N., and Das, S. 2003. Hepatitis C virus internal ribosome entry site-mediated translation is stimulated by specific interaction of independent regions of human La autoantigen. J. Biol. Chem. 278: 12231-12240.
42. Pyronnet, S., Pradayrol, L., and Sonenberg, N. 2000. A cell cycle-dependent internal ribosome entry site. Mol. Cell 5: 607-617.
43. Rajcan-Separovic, E., Liston, P., Lefebvre, C., and Korneluk, R.G. 1996. Assignment of human inhibitor of apoptosis protein (IAP) genes xiap, hiap-1, and hiap-2 to chromosomes Xq25 and 11q22-23 by fluorescence in situ hybridization. Genomics 37: 404-406.
44. Reed, J.C. 2000. Mechanisms of apoptosis. Am. J. Pathol. 157: 1415-1430.
45. Rothe, M., Pan, M.G., Henzel, W.J., Ayres, T.M., and Goeddel, D.V. 1995. The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins. Cell 83: 1243-1252.
46. Roy, N., Deveraux, Q.L., Takahashi, R., Salvesen, G.S., and Reed, J.C. 1997. The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases. EMBO J. 16: 6914-6925.
47. Ryabova, L.A. and Hohn, T. 2000. Ribosome shunting in the cauliflower mosaic virus 35S RNA leader is a special case of reinitiation of translation functioning in plant and animal systems. Genes & Dev. 14: 817-829.
48. Salvesen, G.S. and Duckett, C.S. 2002. IAP proteins: Blocking the road to death's door. Nat. Rev. Mol. Cell Biol. 3: 401-410.
49. Sarnow, P. 2003. Viral internal ribosome entry site elements: Novel ribosome-RNA complexes and roles in viral pathogenesis. J. Virol. 77: 2801-2807.
50. Schmid, M. and Wimmer, E. 1994. IRES-controlled protein synthesis and genome replication of poliovirus. Arch. Virol. Suppl. 9: 279-289.
51. Stein, I., Itin, A., Einat, P., Skaliter, R., Grossman, Z., and Keshet, E. 1998. Translation of vascular endothelial growth factor mRNA by internal ribosome entry: Implications for translation under hypoxia. Mol. Cell Biol. 18: 3112-3119.
52. 2 and laminar fluid shear stress stabilize c-1AP1 in vascular endothelial cells. Am. J. Physiol Heart Circ. Physiol. 285: H38-H46.
53. Tamm, I., Kornblau, S.M., Segall, H., Krajewski, S., Welsh, K., Kitada, S., Scudiero, D.A., Tudor, G., Qui, Y.H., Monks, A., et al. 2000. Expression and prognostic significance of IAP-family genes in human cancers and myeloid leukemias. Clin. Cancer Res. 6: 1796-1803.
54. Van Eden, M.E., Byrd, M.P., Sherrill, K.W., and Lloyd, R.E. 2004. Demonstrating internal ribosome entry sites in eukaryotic mRNAs using stringent RNA test procedures. RNA (in press).
55. Wang, Z. and Kiledjian, M. 2001. Functional link between the mammalian exosome and mRNA decapping. Cell 107: 751-762.
56. Wang, C., Mayo, M.W., Korneluk, R.G., Goeddel, D.V., and Baldwin, A.S. 1998. NF-κB antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation. Science 281: 1680-1683.
57. Yang, Y., Fang, S., Jensen, J.P., Weissman, A.M., and Ashwell, J.D. 2000. Ubiquitin protein ligase activity of 1APs and their degradation in proteosomes in response to apoptotic stimuli. Science 288: 874-877.
58. Young, S.S., Liston, P., Xuan, J., McRoberts, C., Lefebvre, C.A., and Korneluk, R.G. 1999. Genomic organization and physical map of the human inhibitors of apoptosis: HIAP1 and HIAP2. Mamm. Genome 10: 44-48.
59. Zamora, M., Marissen, W.E., and Lloyd, R.E. 2002. Multiple eIF4GI-specific activities present in uninfected and poliovirus-infected cells. J. Virol. 76: 165-177.