Phosphorylation of eIF2 facilitates ribosomal bypass of an inhibitory upstream ORF to enhance CHOP translation

Journal of Biological Chemistry

Volumn 286, Issue 13, 2011, Pages 10939-10949

  Palam, Lakshmi Reddy ^a   Baird, Thomas D ^a   Wek, Ronald C ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS; CODING REGION; ENERGY EXPENDITURE; ENVIRONMENTAL STRESS; EUKARYOTIC INITIATION FACTOR; NEW MECHANISMS; PROTEIN SYNTHESIS; STRESS RESPONSE; STRESS-INDUCED; TARGET GENES; TRANSCRIPTIONAL ACTIVATORS; TRANSCRIPTIONAL REGULATOR;

CELL DEATH; MACROMOLECULES; PHOSPHORYLATION;

GENE EXPRESSION;

ACTIVATING TRANSCRIPTION FACTOR 4; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; INITIATION FACTOR 2; MESSENGER RNA;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CELL FATE; CELLULAR DISTRIBUTION; CELLULAR STRESS RESPONSE; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; RNA TRANSLATION; TRANSCRIPTION INITIATION SITE; TRANSLATION REGULATION;

ACTIVATING TRANSCRIPTION FACTOR 4; ANIMALS; APOPTOSIS; CELL LINE; EUKARYOTIC INITIATION FACTOR-2; MICE; OPEN READING FRAMES; PHOSPHORYLATION; PROTEIN BIOSYNTHESIS; RIBOSOMES; RNA, MESSENGER; STRESS, PHYSIOLOGICAL; TRANSCRIPTION FACTOR CHOP;

EUKARYOTA;

EID: 79953224498     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.216093     Document Type: Article

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