eIF2α kinases GCN2 and PERK modulate transcription and translation of distinct sets of mRNAs in mouse liver

Physiological Genomics

Volumn 38, Issue 3, 2009, Pages 328-341

  Dang Do, An N ^a   Kimball, Scot R ^a   Cavener, Douglas R ^b   Jefferson, Leonard S ^a  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

^b PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

Amino acid deprivation; Endoplasmic reticulum stress; Eukaryotic initiation factor 2 phosphorylation; mRNA translation

Indexed keywords

GENERAL CONTROL NONDEREPRESSIBLE 2; MESSENGER RNA; PKR LIKE ENDOPLASMIC RETICULUM RESIDENT KINASE; PROTEIN KINASE R; UNCLASSIFIED DRUG; 2,5 DI TERT BUTYLHYDROQUINONE; 2,5-DI-TERT-BUTYLHYDROQUINONE; EIF2AK4 PROTEIN, MOUSE; HYDROQUINONE DERIVATIVE; PERK KINASE; PROTEIN SERINE THREONINE KINASE;

ANIMAL EXPERIMENT; ARTICLE; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; LIVER; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; STRESS; TRANSCRIPTION REGULATION; TRANSLATION REGULATION; ANIMAL; C57BL MOUSE; DNA MICROARRAY; DRUG EFFECT; ENZYME ACTIVATION; FEMALE; GENETIC TRANSCRIPTION; GENETICS; MALE; METABOLISM; MOUSE MUTANT; MOUSE STRAIN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN SYNTHESIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

EUKARYOTA; MAMMALIA;

ANIMALS; BLOTTING, WESTERN; EIF-2 KINASE; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME ACTIVATION; FEMALE; HYDROQUINONES; LIVER; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED STRAINS; MICE, KNOCKOUT; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROTEIN BIOSYNTHESIS; PROTEIN-SERINE-THREONINE KINASES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRANSCRIPTION, GENETIC;

EID: 68849087185     PISSN: 10948341     EISSN: 15312267     Source Type: Journal    
DOI: 10.1152/physiolgenomics.90396.2008     Document Type: Article

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