-
1
-
-
38849199203
-
Shared principles in NF-kappaB signaling
-
Hayden MS, Ghosh S. Shared principles in NF-kappaB signaling. Cell 2008; 132:344-362.
-
(2008)
Cell
, vol.132
, pp. 344-362
-
-
Hayden, M.S.1
Ghosh, S.2
-
2
-
-
67650724069
-
Regulation and function of NFkappaB transcription factors in the immune system
-
Vallabhapurapu S, Karin M. Regulation and function of NFkappaB transcription factors in the immune system. Annu Rev Immunol 2009; 27:693-733.
-
(2009)
Annu Rev Immunol
, vol.27
, pp. 693-733
-
-
Vallabhapurapu, S.1
Karin, M.2
-
3
-
-
0026598520
-
The ankyrin repeat domains of the NF-kappa B precursor p105 and the protooncogene bcl-3 act as specific inhibitors of NF-kappa B DNA binding
-
Hatada EN, Nieters A, Wulczyn FG, et al. The ankyrin repeat domains of the NF-kappa B precursor p105 and the protooncogene bcl-3 act as specific inhibitors of NF-kappa B DNA binding. Proc Natl Sci USA 1992; 89:2489-2493.
-
(1992)
Proc Natl Sci USA
, vol.89
, pp. 2489-2493
-
-
Hatada, E.N.1
Nieters, A.2
Wulczyn, F.G.3
-
4
-
-
2342464085
-
The two NF-kappaB activation pathways and their role in innate and adaptive immunity
-
Bonizzi G, Karin M. The two NF-kappaB activation pathways and their role in innate and adaptive immunity. Trends Immunol 2004; 25:280-288.
-
(2004)
Trends Immunol
, vol.25
, pp. 280-288
-
-
Bonizzi, G.1
Karin, M.2
-
5
-
-
4544228457
-
Functions of NF-kappaB1 and NFkappaB2 in immune cell biology
-
Beinke S, Ley SC. Functions of NF-kappaB1 and NFkappaB2 in immune cell biology. Biochem J 2004; 382(Pt 2):393-409.
-
(2004)
Biochem J
, vol.382
, Issue.PART 2
, pp. 393-409
-
-
Beinke, S.1
Ley, S.C.2
-
6
-
-
17944378526
-
Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway
-
Senftleben U, Cao Y, Xiao G, et al. Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway. Science 2001; 293:1495-1499.
-
(2001)
Science
, vol.293
, pp. 1495-1499
-
-
Senftleben, U.1
Cao, Y.2
Xiao, G.3
-
7
-
-
0034745420
-
NF-kappaB-inducing kinase regulates the processing of NF-kappaB2 p100
-
Xiao G, Harhaj EW, Sun SC. NF-kappaB-inducing kinase regulates the processing of NF-kappaB2 p100. Mol Cell 2001; 7:401-409.
-
(2001)
Mol Cell
, vol.7
, pp. 401-409
-
-
Xiao, G.1
Harhaj, E.W.2
Sun, S.C.3
-
8
-
-
18644380147
-
The lymphotoxinbeta receptor induces different patterns of gene expression via two NF-kappaB pathways
-
Dejardin E, Droin NM, Delhase M, et al. The lymphotoxinbeta receptor induces different patterns of gene expression via two NF-kappaB pathways. Immunity 2002; 17:525-535.
-
(2002)
Immunity
, vol.17
, pp. 525-535
-
-
Dejardin, E.1
Droin, N.M.2
Delhase, M.3
-
9
-
-
2942731516
-
Regulation of the NFkappaB-inducing kinase by tumor necrosis factor receptorassociated factor 3-induced degradation
-
Liao G, Zhang M, Harhaj EW, Sun SC. Regulation of the NFkappaB-inducing kinase by tumor necrosis factor receptorassociated factor 3-induced degradation. J Biol Chem 2004; 279:26243-26250.
-
(2004)
J Biol Chem
, vol.279
, pp. 26243-26250
-
-
Liao, G.1
Zhang, M.2
Harhaj, E.W.3
Sun, S.C.4
-
10
-
-
56349164239
-
Noncanonical NFkappaB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK
-
Zarnegar BJ, Wang Y, Mahoney DJ, et al. Noncanonical NFkappaB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK. Nat Immunol 2008; 9:1371-1378.
-
(2008)
Nat Immunol
, vol.9
, pp. 1371-1378
-
-
Zarnegar, B.J.1
Wang, Y.2
Mahoney, D.J.3
-
11
-
-
56349164232
-
Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-kappaB signaling
-
Vallabhapurapu S, Matsuzawa A, Zhang W, et al. Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-kappaB signaling. Nat Immunol 2008; 9:1364-1370.
-
(2008)
Nat Immunol
, vol.9
, pp. 1364-1370
-
-
Vallabhapurapu, S.1
Matsuzawa, A.2
Zhang, W.3
-
12
-
-
3142663912
-
Induction of p100 processing by NF-kappaB-inducing kinase involves docking IkappaB kinase alpha (IKKalpha) to p100 and IKKalpha-mediated phosphorylation
-
Xiao G, Fong A, Sun SC. Induction of p100 processing by NF-kappaB-inducing kinase involves docking IkappaB kinase alpha (IKKalpha) to p100 and IKKalpha-mediated phosphorylation. J Biol Chem 2004; 279:30099-30105.
-
(2004)
J Biol Chem
, vol.279
, pp. 30099-30105
-
-
Xiao, G.1
Fong, A.2
Sun, S.C.3
-
13
-
-
17644390613
-
Controlled elimination of intracellular H(2)O(2): Regulation of peroxiredoxin, catalase, and glutathione peroxidase via posttranslational modification
-
Rhee SG, Yang KS, Kang SW, Woo HA, Chang TS. Controlled elimination of intracellular H(2)O(2): regulation of peroxiredoxin, catalase, and glutathione peroxidase via posttranslational modification. Antioxid Redox Signal 2005; 7:619-626.
-
(2005)
Antioxid Redox Signal
, vol.7
, pp. 619-626
-
-
Rhee, S.G.1
Yang, K.S.2
Kang, S.W.3
Woo, H.A.4
Chang, T.S.5
-
14
-
-
0034534165
-
Antioxidant function of thioredoxin and glutaredoxin systems
-
Holmgren A. Antioxidant function of thioredoxin and glutaredoxin systems. Antioxid Redox Signal 2000; 2:811-820.
-
(2000)
Antioxid Redox Signal
, vol.2
, pp. 811-820
-
-
Holmgren, A.1
-
15
-
-
0030894162
-
Oxidative stress: Oxidants and antioxidants
-
Sies H. Oxidative stress: oxidants and antioxidants. Exp Physiol 1997; 82:291-295.
-
(1997)
Exp Physiol
, vol.82
, pp. 291-295
-
-
Sies, H.1
-
16
-
-
0032080283
-
Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1
-
Saitoh M, Nishitoh H, Fujii M, et al. Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1. EMBO J 1998; 17:2596-2606.
-
(1998)
EMBO J
, vol.17
, pp. 2596-2606
-
-
Saitoh, M.1
Nishitoh, H.2
Fujii, M.3
-
17
-
-
0034001070
-
Activation of apoptosis signal-regulating kinase 1 (ASK1) by tumor necrosis factor receptor-associated factor 2 requires prior dissociation of the ASK1 inhibitor thioredoxin
-
Liu H, Nishitoh H, Ichijo H, Kyriakis JM. Activation of apoptosis signal-regulating kinase 1 (ASK1) by tumor necrosis factor receptor-associated factor 2 requires prior dissociation of the ASK1 inhibitor thioredoxin. Mol Cell Biol 2000; 20:2198-2208.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 2198-2208
-
-
Liu, H.1
Nishitoh, H.2
Ichijo, H.3
Kyriakis, J.M.4
-
18
-
-
27744559915
-
Recruitment of tumor necrosis factor receptor-associated factor family proteins to apoptosis signal-regulating kinase 1 signalosome is essential for oxidative stress-induced cell death
-
Noguchi T, Takeda K, Matsuzawa A et al. Recruitment of tumor necrosis factor receptor-associated factor family proteins to apoptosis signal-regulating kinase 1 signalosome is essential for oxidative stress-induced cell death. J Biol Chem 2005; 280:37033-37040.
-
(2005)
J Biol Chem
, vol.280
, pp. 37033-37040
-
-
Noguchi, T.1
Takeda, K.2
Matsuzawa, A.3
-
19
-
-
0037188936
-
Thioredoxin promotes ASK1 ubiquitination and degradation to inhibit ASK1-mediated apoptosis in a redox activity-independent manner
-
Liu Y, Min W. Thioredoxin promotes ASK1 ubiquitination and degradation to inhibit ASK1-mediated apoptosis in a redox activity-independent manner. Circ Res 2002; 90:1259-1266.
-
(2002)
Circ Res
, vol.90
, pp. 1259-1266
-
-
Liu, Y.1
Min, W.2
-
20
-
-
40949111340
-
SENP1 mediates TNF-induced desumoylation and cytoplasmic translocation of HIPK1 to enhance ASK1-dependent apoptosis
-
Li X, Luo Y, Yu L, et al. SENP1 mediates TNF-induced desumoylation and cytoplasmic translocation of HIPK1 to enhance ASK1-dependent apoptosis. Cell Death Differ 2008; 15:739-750.
-
(2008)
Cell Death Differ
, vol.15
, pp. 739-750
-
-
Li, X.1
Luo, Y.2
Yu, L.3
-
21
-
-
1542406446
-
NOX enzymes and the biology of reactive oxygen
-
Lambeth JD. NOX enzymes and the biology of reactive oxygen. Nat Rev Immunol 2004; 4:181-189.
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 181-189
-
-
Lambeth, J.D.1
-
23
-
-
33745804975
-
The expanding role of NADPH oxidases in health and disease: No longer just agents of death and destruction
-
Quinn MT, Ammons MC, Deleo FR. The expanding role of NADPH oxidases in health and disease: no longer just agents of death and destruction. Clin Sci (Lond) 2006; 111:1-20.
-
(2006)
Clin Sci (Lond)
, vol.111
, pp. 1-20
-
-
Quinn, M.T.1
Ammons, M.C.2
Deleo, F.R.3
-
24
-
-
65349157681
-
Compartmentalization of redox signaling through NADPH oxidase-derived ROS
-
Ushio-Fukai M. Compartmentalization of redox signaling through NADPH oxidase-derived ROS. Antioxid Redox Signal 2009; 11:1289-1299.
-
(2009)
Antioxid Redox Signal
, vol.11
, pp. 1289-1299
-
-
Ushio-Fukai, M.1
-
25
-
-
33744805401
-
Turning point in apoptosis/ necrosis induced by hydrogen peroxide
-
Saito Y, Nishio K, Ogawa Y, et al. Turning point in apoptosis/ necrosis induced by hydrogen peroxide. Free Radic Res 2006; 40:619-630.
-
(2006)
Free Radic Res
, vol.40
, pp. 619-630
-
-
Saito, Y.1
Nishio, K.2
Ogawa, Y.3
-
26
-
-
0033026491
-
Hydrogen peroxide induces necrosis, apoptosis, oncosis and apoptotic oncosis of mouse terminal proximal straight tubule cells
-
Takeda M, Shirato I, Kobayashi M, Endou H. Hydrogen peroxide induces necrosis, apoptosis, oncosis and apoptotic oncosis of mouse terminal proximal straight tubule cells. Nephron 1999; 81:234-238.
-
(1999)
Nephron
, vol.81
, pp. 234-238
-
-
Takeda, M.1
Shirato, I.2
Kobayashi, M.3
Endou, H.4
-
27
-
-
0033005384
-
Hydrogen peroxideinduced apoptosis and necrosis in human lung fibroblasts: Protective roles of glutathione
-
Teramoto S, Tomita T, Matsui H, et al. Hydrogen peroxideinduced apoptosis and necrosis in human lung fibroblasts: protective roles of glutathione. Jpn J Pharmacol 1999; 79:33-40.
-
(1999)
Jpn J Pharmacol
, vol.79
, pp. 33-40
-
-
Teramoto, S.1
Tomita, T.2
Matsui, H.3
-
28
-
-
33645971047
-
Good cop, bad cop: The different faces of NF-kappaB
-
Perkins ND, Gilmore TD. Good cop, bad cop: the different faces of NF-kappaB. Cell Death Differ 2006; 13:759-772.
-
(2006)
Cell Death Differ
, vol.13
, pp. 759-772
-
-
Perkins, N.D.1
Gilmore, T.D.2
-
29
-
-
0036888899
-
The p65/RelA subunit of NF-kappaB suppresses the sustained, antiapoptotic activity of Jun kinase induced by tumor necrosis factor
-
Reuther-Madrid JY, Kashatus D, Chen S, et al. The p65/RelA subunit of NF-kappaB suppresses the sustained, antiapoptotic activity of Jun kinase induced by tumor necrosis factor. Mol Cell Biol 2002; 22:8175-8183.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 8175-8183
-
-
Reuther-Madrid, J.Y.1
Kashatus, D.2
Chen, S.3
-
30
-
-
0036882166
-
The absence of NF-kappaBmediated inhibition of c-Jun N-terminal kinase activation contributes to tumor necrosis factor alpha-induced apoptosis
-
Tang F, Tang G, Xiang J, et al. The absence of NF-kappaBmediated inhibition of c-Jun N-terminal kinase activation contributes to tumor necrosis factor alpha-induced apoptosis. Mol Cell Biol 2002; 22:8571-8579.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 8571-8579
-
-
Tang, F.1
Tang, G.2
Xiang, J.3
-
31
-
-
40249091354
-
TNFalpha and reactive oxygen species in necrotic cell death
-
Morgan MJ, Kim YS, Liu ZG. TNFalpha and reactive oxygen species in necrotic cell death. Cell Res 2008; 18:343-349.
-
(2008)
Cell Res
, vol.18
, pp. 343-349
-
-
Morgan, M.J.1
Kim, Y.S.2
Liu, Z.G.3
-
32
-
-
77955035878
-
Reactive oxygen species in TNFalphainduced signaling and cell death
-
Morgan MJ, Liu ZG. Reactive oxygen species in TNFalphainduced signaling and cell death. Mol Cells 2010; 30:1-12.
-
(2010)
Mol Cells
, vol.30
, pp. 1-12
-
-
Morgan, M.J.1
Liu, Z.G.2
-
33
-
-
33749076455
-
Mechanisms of crosstalk between TNF-induced NF-kappaB and JNK activation in hepatocytes
-
Wullaert A, Heyninck K, Beyaert R. Mechanisms of crosstalk between TNF-induced NF-kappaB and JNK activation in hepatocytes. Biochem Pharmacol 2006; 72:1090-1101.
-
(2006)
Biochem Pharmacol
, vol.72
, pp. 1090-1101
-
-
Wullaert, A.1
Heyninck, K.2
Beyaert, R.3
-
34
-
-
33645965616
-
Reactive oxygen species mediate crosstalk between NF-kappaB and JNK
-
Nakano H, Nakajima A, Sakon-Komazawa S, et al. Reactive oxygen species mediate crosstalk between NF-kappaB and JNK. Cell Death Differ 2006; 13:730-737.
-
(2006)
Cell Death Differ
, vol.13
, pp. 730-737
-
-
Nakano, H.1
Nakajima, A.2
Sakon-Komazawa, S.3
-
35
-
-
33645983982
-
The NF-kappaB-mediated control of the JNK cascade in the antagonism of programmed cell death in health and disease
-
Papa S, Bubici C, Zazzeroni F, et al. The NF-kappaB-mediated control of the JNK cascade in the antagonism of programmed cell death in health and disease. Cell Death Differ 2006; 13:712-729.
-
(2006)
Cell Death Differ
, vol.13
, pp. 712-729
-
-
Papa, S.1
Bubici, C.2
Zazzeroni, F.3
-
36
-
-
34547868171
-
Lipid rafts and oxidative stressinduced cell death
-
Morgan MJ, Kim YS, Liu Z. Lipid rafts and oxidative stressinduced cell death. Antioxid Redox Signal 2007; 9:1471-1483.
-
(2007)
Antioxid Redox Signal
, vol.9
, pp. 1471-1483
-
-
Morgan, M.J.1
Kim, Y.S.2
Liu, Z.3
-
37
-
-
0030692715
-
Tumor necrosis factor alpha and interleukin-1beta regulate the murine manganese superoxide dismutase gene through a complex intronic enhancer involving C/EBP-beta and NF-kappaB
-
Jones PL, Ping D, Boss JM. Tumor necrosis factor alpha and interleukin-1beta regulate the murine manganese superoxide dismutase gene through a complex intronic enhancer involving C/EBP-beta and NF-kappaB. Mol Cell Biol 1997; 17:6970-6981.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 6970-6981
-
-
Jones, P.L.1
Ping, D.2
Boss, J.M.3
-
38
-
-
9644294597
-
NF-kappaB activation prevents apoptotic oxidative stress via an increase of both thioredoxin and MnSOD levels in TNFalpha-treated Ewing sarcoma cells
-
Djavaheri-Mergny M, Javelaud D, Wietzerbin J, Besancon F. NF-kappaB activation prevents apoptotic oxidative stress via an increase of both thioredoxin and MnSOD levels in TNFalpha-treated Ewing sarcoma cells. FEBS Lett 2004; 578:111-115.
-
(2004)
FEBS Lett
, vol.578
, pp. 111-115
-
-
Djavaheri-Mergny, M.1
Javelaud, D.2
Wietzerbin, J.3
Besancon, F.4
-
39
-
-
35348960414
-
Xlinked inhibitor of apoptosis protein increases mitochondrial antioxidants through NF-kappaB activation
-
Kairisalo M, Korhonen L, Blomgren K, Lindholm D. Xlinked inhibitor of apoptosis protein increases mitochondrial antioxidants through NF-kappaB activation. Biochem Biophys Res Commun 2007; 364:138-144.
-
(2007)
Biochem Biophys Res Commun
, vol.364
, pp. 138-144
-
-
Kairisalo, M.1
Korhonen, L.2
Blomgren, K.3
Lindholm, D.4
-
40
-
-
0028829574
-
Activation of NFkappa B and elevation of MnSOD gene expression by thiol reducing agents in lung adenocarcinoma (A549) cells
-
Das KC, Lewis-Molock Y, White CW. Activation of NFkappa B and elevation of MnSOD gene expression by thiol reducing agents in lung adenocarcinoma (A549) cells. Am J Physiol 1995; 269(5 Pt 1):L588-L602.
-
(1995)
Am J Physiol
, vol.269
, Issue.5 PART 1
-
-
Das, K.C.1
Lewis-Molock, Y.2
White, C.W.3
-
41
-
-
0028827252
-
Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase
-
Li Y, Huang TT, Carlson EJ, et al. Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase. Nat Genet 1995; 11:376-381.
-
(1995)
Nat Genet
, vol.11
, pp. 376-381
-
-
Li, Y.1
Huang, T.T.2
Carlson, E.J.3
-
42
-
-
0035062753
-
Invited review: Manganese superoxide dismutase in disease
-
Macmillan-Crow LA, Cruthirds DL. Invited review: manganese superoxide dismutase in disease. Free Radic Res 2001; 34:325-336.
-
(2001)
Free Radic Res
, vol.34
, pp. 325-336
-
-
MacMillan-Crow, L.A.1
Cruthirds, D.L.2
-
43
-
-
0034699513
-
Superoxide dismutase as a target for the selective killing of cancer cells
-
Huang P, Feng L, Oldham EA, Keating MJ, Plunkett W. Superoxide dismutase as a target for the selective killing of cancer cells. Nature 2000; 407:390-395.
-
(2000)
Nature
, vol.407
, pp. 390-395
-
-
Huang, P.1
Feng, L.2
Oldham, E.A.3
Keating, M.J.4
Plunkett, W.5
-
44
-
-
7244243873
-
Regulation of Cu/Zn-superoxide dismutase expression via the phosphatidylinositol 3 kinase/Akt pathway and nuclear factor-kappaB
-
Rojo AI, Salinas M, Martin D, Perona R, Cuadrado A. Regulation of Cu/Zn-superoxide dismutase expression via the phosphatidylinositol 3 kinase/Akt pathway and nuclear factor-kappaB. J Neurosci 2004; 24:7324-7334.
-
(2004)
J Neurosci
, vol.24
, pp. 7324-7334
-
-
Rojo, A.I.1
Salinas, M.2
Martin, D.3
Perona, R.4
Cuadrado, A.5
-
45
-
-
13244277942
-
CuZnSOD deficiency leads to persistent and widespread oxidative damage and hepatocarcinogenesis later in life
-
Elchuri S, Oberley TD, Qi W, et al. CuZnSOD deficiency leads to persistent and widespread oxidative damage and hepatocarcinogenesis later in life. Oncogene 2005; 24:367-380.
-
(2005)
Oncogene
, vol.24
, pp. 367-380
-
-
Elchuri, S.1
Oberley, T.D.2
Qi, W.3
-
46
-
-
8344260568
-
Ferritin heavy chain upregulation by NF-kappaB inhibits TNFalpha-induced apoptosis by suppressing reactive oxygen species
-
Pham CG, Bubici C, Zazzeroni F, et al. Ferritin heavy chain upregulation by NF-kappaB inhibits TNFalpha-induced apoptosis by suppressing reactive oxygen species. Cell 2004; 119:529-542.
-
(2004)
Cell
, vol.119
, pp. 529-542
-
-
Pham, C.G.1
Bubici, C.2
Zazzeroni, F.3
-
47
-
-
0037093202
-
Regulation of ferritin genes and protein
-
Torti FM, Torti SV. Regulation of ferritin genes and protein. Blood 2002; 99:3505-3516.
-
(2002)
Blood
, vol.99
, pp. 3505-3516
-
-
Torti, F.M.1
Torti, S.V.2
-
48
-
-
0035578227
-
NF kappa B and AP-1 mediate transcriptional responses to oxidative stress in skeletal muscle cells
-
Zhou LZ, Johnson AP, Rando TA. NF kappa B and AP-1 mediate transcriptional responses to oxidative stress in skeletal muscle cells. Free Radic Biol Med 2001; 31:1405-1416.
-
(2001)
Free Radic Biol Med
, vol.31
, pp. 1405-1416
-
-
Zhou, L.Z.1
Johnson, A.P.2
Rando, T.A.3
-
49
-
-
33645809747
-
Coordinated binding of NF-kappaB family members in the response of human cells to lipopolysaccharide
-
Schreiber J, Jenner RG, Murray HL, et al. Coordinated binding of NF-kappaB family members in the response of human cells to lipopolysaccharide. Proc Natl Acad Sci USA 2006; 103:5899-5904.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 5899-5904
-
-
Schreiber, J.1
Jenner, R.G.2
Murray, H.L.3
-
50
-
-
2042470971
-
Early embryonic lethality caused by targeted disruption of the mouse thioredoxin gene
-
Matsui M, Oshima M, Oshima H, et al. Early embryonic lethality caused by targeted disruption of the mouse thioredoxin gene. Dev Biol 1996; 178:179-185.
-
(1996)
Dev Biol
, vol.178
, pp. 179-185
-
-
Matsui, M.1
Oshima, M.2
Oshima, H.3
-
51
-
-
18444365267
-
Thioredoxin-2 (TRX-2) is an essential gene regulating mitochondria-dependent apoptosis
-
Tanaka T, Hosoi F, Yamaguchi-Iwai Y, et al. Thioredoxin-2 (TRX-2) is an essential gene regulating mitochondria-dependent apoptosis. EMBO J 2002; 21:1695-1703.
-
(2002)
EMBO J
, vol.21
, pp. 1695-1703
-
-
Tanaka, T.1
Hosoi, F.2
Yamaguchi-Iwai, Y.3
-
52
-
-
0037305881
-
The absence of mitochondrial thioredoxin 2 causes massive apoptosis, exencephaly, and early embryonic lethality in homozygous mice
-
Nonn L, Williams RR, Erickson RP, Powis G. The absence of mitochondrial thioredoxin 2 causes massive apoptosis, exencephaly, and early embryonic lethality in homozygous mice. Mol Cell Biol 2003; 23:916-922.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 916-922
-
-
Nonn, L.1
Williams, R.R.2
Erickson, R.P.3
Powis, G.4
-
53
-
-
0030022244
-
The organization of the human GSTP1-1 gene promoter and its response to retinoic acid and cellular redox status
-
Xia C, Hu J, Ketterer B, Taylor JB. The organization of the human GSTP1-1 gene promoter and its response to retinoic acid and cellular redox status. Biochem J 1996; 313(Pt 1):155-161.
-
(1996)
Biochem J
, vol.313
, Issue.PART 1
, pp. 155-161
-
-
Xia, C.1
Hu, J.2
Ketterer, B.3
Taylor, J.B.4
-
55
-
-
0032955185
-
Glutathione S-transferases-a review
-
Salinas AE, Wong MG. Glutathione S-transferases-a review. Curr Med Chem 1999; 6:279-309.
-
(1999)
Curr Med Chem
, vol.6
, pp. 279-309
-
-
Salinas, A.E.1
Wong, M.G.2
-
56
-
-
27144492939
-
Glutathione S-transferase pi1 promotes tumorigenicity in HCT116 human colon cancer cells
-
Dang DT, Chen F, Kohli M, et al. Glutathione S-transferase pi1 promotes tumorigenicity in HCT116 human colon cancer cells. Cancer Res 2005; 65:9485-9494.
-
(2005)
Cancer Res
, vol.65
, pp. 9485-9494
-
-
Dang, D.T.1
Chen, F.2
Kohli, M.3
-
57
-
-
0037417129
-
Divergent gene regulation and growth effects by NF-kappa B in epithelial and mesenchymal cells of human skin
-
Hinata K, Gervin AM, Jennifer Zhang Y, Khavari PA. Divergent gene regulation and growth effects by NF-kappa B in epithelial and mesenchymal cells of human skin. Oncogene 2003; 22:1955-1964.
-
(2003)
Oncogene
, vol.22
, pp. 1955-1964
-
-
Hinata, K.1
Gervin, A.M.2
Jennifer Zhang, Y.3
Khavari, P.A.4
-
58
-
-
77954350284
-
Neuronal growth-inhibitory factor (metallothionein-3): Evaluation of the biological function of growth-inhibitory factor in the injured and neurodegenerative brain
-
Howells C, West AK, Chung RS. Neuronal growth-inhibitory factor (metallothionein-3): evaluation of the biological function of growth-inhibitory factor in the injured and neurodegenerative brain. FEBS J 2010; 277:2931-2939.
-
(2010)
FEBS J
, vol.277
, pp. 2931-2939
-
-
Howells, C.1
West, A.K.2
Chung, R.S.3
-
59
-
-
0002546264
-
Free radical scavenging actions of metallothionein isoforms i and II
-
Kumari MV, Hiramatsu M, Ebadi M. Free radical scavenging actions of metallothionein isoforms I and II. Free Radic Res 1998; 29:93-101.
-
(1998)
Free Radic Res
, vol.29
, pp. 93-101
-
-
Kumari, M.V.1
Hiramatsu, M.2
Ebadi, M.3
-
60
-
-
0030996269
-
Involvement of activator protein-1 and nuclear factor-kappaB transcription factors in the control of the DT-diaphorase expression induced by mitomycin C treatment
-
Yao KS, Hageboutros A, Ford P, O'Dwyer PJ. Involvement of activator protein-1 and nuclear factor-kappaB transcription factors in the control of the DT-diaphorase expression induced by mitomycin C treatment. Mol Pharmacol 1997; 51:422-430.
-
(1997)
Mol Pharmacol
, vol.51
, pp. 422-430
-
-
Yao, K.S.1
Hageboutros, A.2
Ford, P.3
O'Dwyer, P.J.4
-
61
-
-
77956171147
-
NAD(P)H:quinone acceptor oxidoreductase 1 (NQO1), a multifunctional antioxidant enzyme and exceptionally versatile cytoprotector
-
Dinkova-Kostova AT, Talalay P. NAD(P)H:quinone acceptor oxidoreductase 1 (NQO1), a multifunctional antioxidant enzyme and exceptionally versatile cytoprotector. Arch Biochem Biophys 2010; 501:116-123.
-
(2010)
Arch Biochem Biophys
, vol.501
, pp. 116-123
-
-
Dinkova-Kostova, A.T.1
Talalay, P.2
-
62
-
-
33745978116
-
Genetic deletion of NAD(P)H:quinone oxidoreductase 1 abrogates activation of nuclear factor-kappaB, IkappaBalpha kinase, c-Jun N-terminal kinase, Akt, p38, and p44/42 mitogen-activated protein kinases and potentiates apoptosis
-
Ahn KS, Sethi G, Jain AK, Jaiswal AK, Aggarwal BB. Genetic deletion of NAD(P)H:quinone oxidoreductase 1 abrogates activation of nuclear factor-kappaB, IkappaBalpha kinase, c-Jun N-terminal kinase, Akt, p38, and p44/42 mitogen-activated protein kinases and potentiates apoptosis. J Biol Chem 2006; 281:19798-19808.
-
(2006)
J Biol Chem
, vol.281
, pp. 19798-19808
-
-
Ahn, K.S.1
Sethi, G.2
Jain, A.K.3
Jaiswal, A.K.4
Aggarwal, B.B.5
-
63
-
-
0028307310
-
Identification of binding sites for transcription factors NF-kappa B and AP-2 in the promoter region of the human heme oxygenase 1 gene
-
Lavrovsky Y, Schwartzman ML, Levere RD, Kappas A, Abraham NG. Identification of binding sites for transcription factors NF-kappa B and AP-2 in the promoter region of the human heme oxygenase 1 gene. Proc Natl Acad Sci USA 1994; 91:5987-5991.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 5987-5991
-
-
Lavrovsky, Y.1
Schwartzman, M.L.2
Levere, R.D.3
Kappas, A.4
Abraham, N.G.5
-
64
-
-
10344228211
-
Phosphorylation and hypoxia-induced heme oxygenase-1 gene expression in cardiomyocytes
-
Wu G, Marin-Garcia J, Rogers TB, Lakatta EG, Long X. Phosphorylation and hypoxia-induced heme oxygenase-1 gene expression in cardiomyocytes. J Card Fail 2004; 10:519-526.
-
(2004)
J Card Fail
, vol.10
, pp. 519-526
-
-
Wu, G.1
Marin-Garcia, J.2
Rogers, T.B.3
Lakatta, E.G.4
Long, X.5
-
65
-
-
33847381862
-
Transforming growth factor-beta1 stimulates heme oxygenase-1 expression via the PI3K/Akt and NF-kappaB pathways in human lung epithelial cells
-
Lin CC, Chiang LL, Lin CH, et al. Transforming growth factor-beta1 stimulates heme oxygenase-1 expression via the PI3K/Akt and NF-kappaB pathways in human lung epithelial cells. Eur J Pharmacol 2007; 560:101-109.
-
(2007)
Eur J Pharmacol
, vol.560
, pp. 101-109
-
-
Lin, C.C.1
Chiang, L.L.2
Ch, L.3
-
66
-
-
28844446987
-
Molecular basis of heme oxygenase-1 induction: Implications for chemoprevention and chemoprotection
-
Prawan A, Kundu JK, Surh YJ. Molecular basis of heme oxygenase-1 induction: implications for chemoprevention and chemoprotection. Antioxid Redox Signal 2005; 7:1688-1703.
-
(2005)
Antioxid Redox Signal
, vol.7
, pp. 1688-1703
-
-
Prawan, A.1
Kundu, J.K.2
Surh, Y.J.3
-
67
-
-
38449089024
-
Metabolic regulation and function of glutathione peroxidase-1
-
Lei XG, Cheng WH, McClung JP. Metabolic regulation and function of glutathione peroxidase-1. Annu Rev Nutr 2007; 27:41-61.
-
(2007)
Annu Rev Nutr
, vol.27
, pp. 41-61
-
-
Lei, X.G.1
Cheng, W.H.2
McClung, J.P.3
-
68
-
-
0030834975
-
Glutathione peroxidase protects against peroxynitrite-mediated oxidations. A new function for selenoproteins as peroxynitrite reductase
-
Sies H, Sharov VS, Klotz LO, Briviba K. Glutathione peroxidase protects against peroxynitrite-mediated oxidations. A new function for selenoproteins as peroxynitrite reductase. J Biol Chem 1997; 272:27812-27817.
-
(1997)
J Biol Chem
, vol.272
, pp. 27812-27817
-
-
Sies, H.1
Sharov, V.S.2
Klotz, L.O.3
Briviba, K.4
-
70
-
-
0030065647
-
Generation of reactive oxygen species during the enzymatic oxidation of polycyclic aromatic hydrocarbon trans-dihydrodiols catalyzed by dihydrodiol dehydrogenase
-
Penning TM, Ohnishi ST, Ohnishi T, Harvey RG. Generation of reactive oxygen species during the enzymatic oxidation of polycyclic aromatic hydrocarbon trans-dihydrodiols catalyzed by dihydrodiol dehydrogenase. Chem Res Toxicol 1996; 9:84-92.
-
(1996)
Chem Res Toxicol
, vol.9
, pp. 84-92
-
-
Penning, T.M.1
Ohnishi, S.T.2
Ohnishi, T.3
Harvey, R.G.4
-
71
-
-
41049113672
-
Dihydrodiol dehydrogenases regulate the generation of reactive oxygen species and the development of cisplatin resistance in human ovarian carcinoma cells
-
Chen J, Adikari M, Pallai R, Parekh HK, Simpkins H. Dihydrodiol dehydrogenases regulate the generation of reactive oxygen species and the development of cisplatin resistance in human ovarian carcinoma cells. Cancer Chemother Pharmacol 2008; 61:979-987.
-
(2008)
Cancer Chemother Pharmacol
, vol.61
, pp. 979-987
-
-
Chen, J.1
Adikari, M.2
Pallai, R.3
Parekh, H.K.4
Simpkins, H.5
-
72
-
-
33646831500
-
NF-kappaB regulates phagocytic NADPH oxidase by inducing the expression of gp91phox
-
Anrather J, Racchumi G, Iadecola C. NF-kappaB regulates phagocytic NADPH oxidase by inducing the expression of gp91phox. J Biol Chem 2006; 281:5657-5667.
-
(2006)
J Biol Chem
, vol.281
, pp. 5657-5667
-
-
Anrather, J.1
Racchumi, G.2
Iadecola, C.3
-
73
-
-
0029900435
-
Molecular cloning and characterization of the human xanthine dehydrogenase gene (XDH)
-
Xu P, Huecksteadt TP, Hoidal JR. Molecular cloning and characterization of the human xanthine dehydrogenase gene (XDH). Genomics 1996; 34:173-180.
-
(1996)
Genomics
, vol.34
, pp. 173-180
-
-
Xu, P.1
Huecksteadt, T.P.2
Hoidal, J.R.3
-
74
-
-
0029347181
-
Flavoprotein structure and mechanism 4. Xanthine oxidase and xanthine dehydrogenase
-
Hille R, Nishino T. Flavoprotein structure and mechanism. 4. Xanthine oxidase and xanthine dehydrogenase. FASEB J 1995; 9:995-1003.
-
(1995)
FASEB J
, vol.9
, pp. 995-1003
-
-
Hille, R.1
Nishino, T.2
-
75
-
-
24144435946
-
NADH oxidase activity of rat liver xanthine dehydrogenase and xanthine oxidase-contribution for damage mechanisms
-
Maia L, Vala A, Mira L. NADH oxidase activity of rat liver xanthine dehydrogenase and xanthine oxidase-contribution for damage mechanisms. Free Radic Res 2005; 39:979-986.
-
(2005)
Free Radic Res
, vol.39
, pp. 979-986
-
-
Maia, L.1
Vala, A.2
Mira, L.3
-
76
-
-
0029941097
-
Transcriptional regulation of the human iNOS gene in vascular- smoothmuscle cells and macrophages: Evidence for tissue specificity
-
Kolyada AY, Savikovsky N, Madias NE. Transcriptional regulation of the human iNOS gene in vascular-smoothmuscle cells and macrophages: evidence for tissue specificity. Biochem Biophys Res Commun 1996; 220:600-605.
-
(1996)
Biochem Biophys Res Commun
, vol.220
, pp. 600-605
-
-
Kolyada, A.Y.1
Savikovsky, N.2
Madias, N.E.3
-
77
-
-
42549148380
-
Sphingosine-1-phosphate induces an antiinflammatory phenotype in macrophages
-
Hughes JE, Srinivasan S, Lynch KR, et al. Sphingosine-1-phosphate induces an antiinflammatory phenotype in macrophages. Circ Res 2008; 102:950-958.
-
(2008)
Circ Res
, vol.102
, pp. 950-958
-
-
Hughes, J.E.1
Srinivasan, S.2
Lynch, K.R.3
-
78
-
-
33846849033
-
Identification of a classic cytokine-induced enhancer upstream in the human iNOS promoter
-
Guo Z, Shao L, Du Q, Park KS, Geller DA. Identification of a classic cytokine-induced enhancer upstream in the human iNOS promoter. FASEB J 2007; 21:535-542.
-
(2007)
FASEB J
, vol.21
, pp. 535-542
-
-
Guo, Z.1
Shao, L.2
Du, Q.3
Park, K.S.4
Geller, D.A.5
-
79
-
-
0037332589
-
Role of the NF-kappaB signaling pathway and kappaB cis-regulatory elements on the IRF-1 and iNOS promoter regions in mycobacterial lipoarabinomannan induction of nitric oxide
-
Morris KR, Lutz RD, Choi HS, et al. Role of the NF-kappaB signaling pathway and kappaB cis-regulatory elements on the IRF-1 and iNOS promoter regions in mycobacterial lipoarabinomannan induction of nitric oxide. Infect Immun 2003; 71:1442-1452.
-
(2003)
Infect Immun
, vol.71
, pp. 1442-1452
-
-
Morris, K.R.1
Lutz, R.D.2
Choi, H.S.3
-
80
-
-
33847626299
-
Statin treatment upregulates vascular neuronal nitric oxide synthase through Akt/ NF-kappaB pathway
-
Nakata S, Tsutsui M, Shimokawa H et al. Statin treatment upregulates vascular neuronal nitric oxide synthase through Akt/ NF-kappaB pathway. Arterioscler Thromb Vasc Biol 2007; 27:92-98.
-
(2007)
Arterioscler Thromb Vasc Biol
, vol.27
, pp. 92-98
-
-
Nakata, S.1
Tsutsui, M.2
Shimokawa, H.3
-
81
-
-
34248205235
-
Regulation of neuronal nitric oxide synthase exon 1f gene expression by nuclear factor-kappaB acetylation in human neuroblastoma cells
-
Li Y, Zhao Y, Li G, et al. Regulation of neuronal nitric oxide synthase exon 1f gene expression by nuclear factor-kappaB acetylation in human neuroblastoma cells. J Neurochem 2007; 101:1194-1204.
-
(2007)
J Neurochem
, vol.101
, pp. 1194-1204
-
-
Li, Y.1
Zhao, Y.2
Li, G.3
-
82
-
-
70350689746
-
Biochemical and cellular toxicology of peroxynitrite: Implications in cell death and autoimmune phenomenon
-
Ahmad R, Rasheed Z, Ahsan H. Biochemical and cellular toxicology of peroxynitrite: implications in cell death and autoimmune phenomenon. Immunopharmacol Immunotoxicol 2009; 31:388-396.
-
(2009)
Immunopharmacol Immunotoxicol
, vol.31
, pp. 388-396
-
-
Ahmad, R.1
Rasheed, Z.2
Ahsan, H.3
-
83
-
-
63849103058
-
Role of peroxynitrite in the redox regulation of cell signal transduction pathways
-
Liaudet L, Vassalli G, Pacher P. Role of peroxynitrite in the redox regulation of cell signal transduction pathways. Front Biosci 2009; 14:4809-4814.
-
(2009)
Front Biosci
, vol.14
, pp. 4809-4814
-
-
Liaudet, L.1
Vassalli, G.2
Pacher, P.3
-
84
-
-
0038813706
-
Up-regulation of p300 binding and p50 acetylation in tumor necrosis factor-alpha-induced cyclooxygenase-2 promoter activation
-
Deng WG, Zhu Y, Wu KK. Up-regulation of p300 binding and p50 acetylation in tumor necrosis factor-alpha-induced cyclooxygenase-2 promoter activation. J Biol Chem 2003; 278:4770-4777.
-
(2003)
J Biol Chem
, vol.278
, pp. 4770-4777
-
-
Deng, W.G.1
Zhu, Y.2
Wu, K.K.3
-
85
-
-
0032489318
-
Transcriptional role of the nuclear factor kappa B site in the induction by lipopolysaccharide and suppression by dexamethasone of cyclooxygenase-2 in U937 cells
-
Inoue H, Tanabe T. Transcriptional role of the nuclear factor kappa B site in the induction by lipopolysaccharide and suppression by dexamethasone of cyclooxygenase-2 in U937 cells. Biochem Biophys Res Commun 1998; 244:143-148.
-
(1998)
Biochem Biophys Res Commun
, vol.244
, pp. 143-148
-
-
Inoue, H.1
Tanabe, T.2
-
86
-
-
0033551847
-
Arachidonic acid oxygenation by COX-1 and COX-2. Mechanisms of catalysis and inhibition
-
Marnett LJ, Rowlinson SW, Goodwin DC, Kalgutkar AS, Lanzo CA. Arachidonic acid oxygenation by COX-1 and COX-2. Mechanisms of catalysis and inhibition. J Biol Chem 1999; 274:22903-22906.
-
(1999)
J Biol Chem
, vol.274
, pp. 22903-22906
-
-
Marnett, L.J.1
Rowlinson, S.W.2
Goodwin, D.C.3
Kalgutkar, A.S.4
Lanzo, C.A.5
-
87
-
-
0028964296
-
The transcriptional regulation of human arachidonate 12-lipoxygenase gene by NF kappa B/Rel
-
Arakawa T, Nakamura M, Yoshimoto T, Yamamoto S. The transcriptional regulation of human arachidonate 12-lipoxygenase gene by NF kappa B/Rel. FEBS Lett 1995; 363:105-110.
-
(1995)
FEBS Lett
, vol.363
, pp. 105-110
-
-
Arakawa, T.1
Nakamura, M.2
Yoshimoto, T.3
Yamamoto, S.4
-
89
-
-
33947168787
-
Inducible expression of 15-lipoxygenase-2 and 8-lipoxygenase inhibits cell growth via common signaling pathways
-
Schweiger D, Furstenberger G, Krieg P. Inducible expression of 15-lipoxygenase-2 and 8-lipoxygenase inhibits cell growth via common signaling pathways. J Lipid Res 2007; 48:553-564.
-
(2007)
J Lipid Res
, vol.48
, pp. 553-564
-
-
Schweiger, D.1
Furstenberger, G.2
Krieg, P.3
-
90
-
-
0037411282
-
4-Hydroxy-2-nonenal: A product and mediator of oxidative stress
-
Uchida K. 4-Hydroxy-2-nonenal: a product and mediator of oxidative stress. Prog Lipid Res 2003; 42:318-343.
-
(2003)
Prog Lipid Res
, vol.42
, pp. 318-343
-
-
Uchida, K.1
-
91
-
-
50949128741
-
Cytosolic phospholipase A( 2), lipoxygenase metabolites, and reactive oxygen species
-
Kim C, Kim JY, Kim JH. Cytosolic phospholipase A(2), lipoxygenase metabolites, and reactive oxygen species. BMB Rep 2008; 41:555-559.
-
(2008)
BMB Rep
, vol.41
, pp. 555-559
-
-
Kim, C.1
Kim, J.Y.2
Kim, J.H.3
-
92
-
-
0000701892
-
The oxidation of drugs by liver microsomes: On the role of TPNH and oxygen
-
Gillette JR, Brodie BB, La Du BN. The oxidation of drugs by liver microsomes: on the role of TPNH and oxygen. J Pharmacol Exp Ther 1957; 119:532-540.
-
(1957)
J Pharmacol Exp Ther
, vol.119
, pp. 532-540
-
-
Gillette, J.R.1
Brodie, B.B.2
La Du, B.N.3
-
93
-
-
0015298529
-
Hepatic microsomal ethanol oxidation. Hydrogen peroxide formation and the role of catalase
-
Thurman RG, Ley HG, Scholz R. Hepatic microsomal ethanol oxidation. Hydrogen peroxide formation and the role of catalase. Eur J Biochem 1972; 25:420-430.
-
(1972)
Eur J Biochem
, vol.25
, pp. 420-430
-
-
Thurman, R.G.1
Ley, H.G.2
Scholz, R.3
-
94
-
-
0017409578
-
Hydrogen peroxide formation and stoichiometry of hydroxylation reactions catalyzed by highly purified liver microsomal cytochrome P-450
-
Nordblom GD, Coon MJ. Hydrogen peroxide formation and stoichiometry of hydroxylation reactions catalyzed by highly purified liver microsomal cytochrome P-450. Arch Biochem Biophys 1977; 180:343-347.
-
(1977)
Arch Biochem Biophys
, vol.180
, pp. 343-347
-
-
Nordblom, G.D.1
Coon, M.J.2
-
95
-
-
0346724935
-
Role of phenobarbital-inducible cytochrome P450s as a source of active oxygen species in DNA-oxidation
-
Imaoka S, Osada M, Minamiyama Y, et al. Role of phenobarbital-inducible cytochrome P450s as a source of active oxygen species in DNA-oxidation. Cancer Lett 2004; 203:117-125.
-
(2004)
Cancer Lett
, vol.203
, pp. 117-125
-
-
Imaoka, S.1
Osada, M.2
Minamiyama, Y.3
-
96
-
-
4444367613
-
Determination of interleukin-4-responsive region in the human cytochrome P450 2E1 gene promoter
-
Abdel-Razzak Z, Garlatti M, Aggerbeck M, Barouki R. Determination of interleukin-4-responsive region in the human cytochrome P450 2E1 gene promoter. Biochem Pharmacol 2004; 68:1371-1381.
-
(2004)
Biochem Pharmacol
, vol.68
, pp. 1371-1381
-
-
Abdel-Razzak, Z.1
Garlatti, M.2
Aggerbeck, M.3
Barouki, R.4
-
97
-
-
0037184799
-
Mechanisms of cytochrome P450 regulation by inflammatory mediators
-
Morgan ET, Li-Masters T, Cheng PY. Mechanisms of cytochrome P450 regulation by inflammatory mediators. Toxicology 2002; 181-182:207-210.
-
(2002)
Toxicology
, vol.181-182
, pp. 207-210
-
-
Morgan, E.T.1
Li-Masters, T.2
Cheng, P.Y.3
-
98
-
-
33644697202
-
Tumour necrosis factor-alpha stimulates dehydroepiandrosterone metabolism in human fibroblast-like synoviocytes: A role for nuclear factor-kappaB and activator protein-1 in the regulation of expression of cytochrome p450 enzyme 7b
-
Dulos J, Kaptein A, Kavelaars A, Heijnen C, Boots A. Tumour necrosis factor-alpha stimulates dehydroepiandrosterone metabolism in human fibroblast-like synoviocytes: a role for nuclear factor-kappaB and activator protein-1 in the regulation of expression of cytochrome p450 enzyme 7b. Arthritis Res Ther 2005; 7:R1271-R1280.
-
(2005)
Arthritis Res Ther
, vol.7
-
-
Dulos, J.1
Kaptein, A.2
Kavelaars, A.3
Heijnen, C.4
Boots, A.5
-
99
-
-
1342323673
-
Oxidative stress, toxicology, and pharmacology of CYP2E1
-
Caro AA, Cederbaum AI. Oxidative stress, toxicology, and pharmacology of CYP2E1. Annu Rev Pharmacol Toxicol 2004; 44:27-42.
-
(2004)
Annu Rev Pharmacol Toxicol
, vol.44
, pp. 27-42
-
-
Caro, A.A.1
Cederbaum, A.I.2
-
100
-
-
0035894132
-
CYP2E1-dependent toxicity and oxidative stress in HepG2 cells
-
Cederbaum AI, Wu D, Mari M, Bai J. CYP2E1-dependent toxicity and oxidative stress in HepG2 cells. Free Radic Biol Med 2001; 31:1539-1543.
-
(2001)
Free Radic Biol Med
, vol.31
, pp. 1539-1543
-
-
Cederbaum, A.I.1
Wu, D.2
Mari, M.3
Bai, J.4
-
101
-
-
0037155835
-
Cytochrome P450 2E1-derived reactive oxygen species mediate paracrine stimulation of collagen I protein synthesis by hepatic stellate cells
-
DOI 10.1074/jbc.M110506200
-
Nieto N, Friedman SL, Cederbaum AI. Cytochrome P450 2E1-derived reactive oxygen species mediate paracrine stimulation of collagen I protein synthesis by hepatic stellate cells. J Biol Chem 2002; 277:9853-9864. (Pubitemid 34968090)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.12
, pp. 9853-9864
-
-
Nieto, N.1
Friedman, S.L.2
Cederbaum, A.I.3
-
102
-
-
14044277556
-
Redox regulation of NF-kappaB activation: Distinct redox regulation between the cytoplasm and the nucleus
-
Kabe Y, Ando K, Hirao S, Yoshida M, Handa H. Redox regulation of NF-kappaB activation: distinct redox regulation between the cytoplasm and the nucleus. Antioxid Redox Signal 2005; 7:395-403.
-
(2005)
Antioxid Redox Signal
, vol.7
, pp. 395-403
-
-
Kabe, Y.1
Ando, K.2
Hirao, S.3
Yoshida, M.4
Handa, H.5
-
103
-
-
0027269781
-
H2O2 and antioxidants have opposite effects on activation of NF-kappa B and AP-1 in intact cells: AP-1 as secondary antioxidant-responsive factor
-
Meyer M, Schreck R, Baeuerle PA. H2O2 and antioxidants have opposite effects on activation of NF-kappa B and AP-1 in intact cells: AP-1 as secondary antioxidant-responsive factor. EMBO J 1993; 12:2005-2015.
-
(1993)
EMBO J
, vol.12
, pp. 2005-2015
-
-
Meyer, M.1
Schreck, R.2
Baeuerle, P.A.3
-
104
-
-
0030936568
-
AP-1 transcriptional activity is regulated by a direct association between thioredoxin and Ref-1
-
Hirota K, Matsui M, Iwata S, et al. AP-1 transcriptional activity is regulated by a direct association between thioredoxin and Ref-1. Proc Natl Acad Sci USA 1997; 94:3633-3638.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 3633-3638
-
-
Hirota, K.1
Matsui, M.2
Iwata, S.3
-
105
-
-
0033600744
-
Distinct roles of thioredoxin in the cytoplasm and in the nucleus. A two-step mecha nism of redox regulation of transcription factor NF-kappaB
-
Hirota K, Murata M, Sachi Y, et al. Distinct roles of thioredoxin in the cytoplasm and in the nucleus. A two-step mecha nism of redox regulation of transcription factor NF-kappaB. J Biol Chem 1999; 274:27891-27897.
-
(1999)
J Biol Chem
, vol.274
, pp. 27891-27897
-
-
Hirota, K.1
Murata, M.2
Sachi, Y.3
-
106
-
-
75749123115
-
Orchestrating redox signaling networks through regulatory cysteine switches
-
Paulsen CE, Carroll KS. Orchestrating redox signaling networks through regulatory cysteine switches. ACS Chem Biol 2010; 5:47-62.
-
(2010)
ACS Chem Biol
, vol.5
, pp. 47-62
-
-
Paulsen, C.E.1
Carroll, K.S.2
-
107
-
-
15444374584
-
Differential oxidation of protein-tyrosine phosphatases
-
Groen A, Lemeer S, van der Wijk T, et al. Differential oxidation of protein-tyrosine phosphatases. J Biol Chem 2005; 280:10298-10304.
-
(2005)
J Biol Chem
, vol.280
, pp. 10298-10304
-
-
Groen, A.1
Lemeer, S.2
Van Der Wijk, T.3
-
108
-
-
0036019941
-
Redox-linked signal transduction pathways for protein tyrosine kinase activation
-
Nakashima I, Kato M, Akhand AA, et al. Redox-linked signal transduction pathways for protein tyrosine kinase activation. Antioxid Redox Signal 2002; 4:517-531.
-
(2002)
Antioxid Redox Signal
, vol.4
, pp. 517-531
-
-
Nakashima, I.1
Kato, M.2
Akhand, A.A.3
-
109
-
-
11144285380
-
Redox control of catalytic activities of membrane-associated protein tyrosine kinases
-
Nakashima I, Takeda K, Kawamoto Y, et al. Redox control of catalytic activities of membrane-associated protein tyrosine kinases. Arch Biochem Biophys 2005; 434:3-10.
-
(2005)
Arch Biochem Biophys
, vol.434
, pp. 3-10
-
-
Nakashima, I.1
Takeda, K.2
Kawamoto, Y.3
-
110
-
-
14844327760
-
Reactive oxygen species promote TNFalpha-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases
-
Kamata H, Honda S, Maeda S, et al. Reactive oxygen species promote TNFalpha-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases. Cell 2005; 120:649-661.
-
(2005)
Cell
, vol.120
, pp. 649-661
-
-
Kamata, H.1
Honda, S.2
Maeda, S.3
-
112
-
-
0025852479
-
Modulation of transcription factor NF-kappa B binding activity by oxidation-reduction in vitro
-
Toledano MB, Leonard WJ. Modulation of transcription factor NF-kappa B binding activity by oxidation-reduction in vitro. Proc Natl Acad Sci USA 1991; 88:4328-4332.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 4328-4332
-
-
Toledano, M.B.1
Leonard, W.J.2
-
113
-
-
0027500138
-
N-terminal DNA-binding domains contribute to differential DNA-binding specificities of NF-kappa B p50 and p65
-
Toledano MB, Ghosh D, Trinh F, Leonard WJ. N-terminal DNA-binding domains contribute to differential DNA-binding specificities of NF-kappa B p50 and p65. Mol Cell Biol 1993; 13:852-860.
-
(1993)
Mol Cell Biol
, vol.13
, pp. 852-860
-
-
Toledano, M.B.1
Ghosh, D.2
Trinh, F.3
Leonard, W.J.4
-
114
-
-
0027336278
-
Role of cysteine62 in DNA recognition by the P50 subunit of NF-kappa B
-
Matthews JR, Kaszubska W, Turcatti G, Wells TN, Hay RT. Role of cysteine62 in DNA recognition by the P50 subunit of NF-kappa B. Nucleic Acids Res 1993; 21:1727-1734.
-
(1993)
Nucleic Acids Res
, vol.21
, pp. 1727-1734
-
-
Matthews, J.R.1
Kaszubska, W.2
Turcatti, G.3
Wells, T.N.4
Hay, R.T.5
-
115
-
-
0026715172
-
Thioredoxin regulates the DNA binding activity of NF-kappa B by reduction of a disulphide bond involving cysteine 62
-
Matthews JR, Wakasugi N, Virelizier JL, Yodoi J, Hay RT. Thioredoxin regulates the DNA binding activity of NF-kappa B by reduction of a disulphide bond involving cysteine 62. Nucleic Acids Res 1992; 20:3821-3830.
-
(1992)
Nucleic Acids Res
, vol.20
, pp. 3821-3830
-
-
Matthews, J.R.1
Wakasugi, N.2
Virelizier, J.L.3
Yodoi, J.4
Hay, R.T.5
-
116
-
-
0033869092
-
Regulation of protein function by S-glutathiolation in response to oxidative and nitrosative stress
-
Klatt P, Lamas S. Regulation of protein function by S-glutathiolation in response to oxidative and nitrosative stress. Eur J Biochem 2000; 267:4928-4944.
-
(2000)
Eur J Biochem
, vol.267
, pp. 4928-4944
-
-
Klatt, P.1
Lamas, S.2
-
117
-
-
0035960648
-
Glutathionylation of the p50 subunit of NF-kappaB: A mechanism for redoxinduced inhibition of DNA binding
-
Pineda-Molina E, Klatt P, Vazquez J, et al. Glutathionylation of the p50 subunit of NF-kappaB: a mechanism for redoxinduced inhibition of DNA binding. Biochemistry 2001; 40:14134-14142.
-
(2001)
Biochemistry
, vol.40
, pp. 14134-14142
-
-
Pineda-Molina, E.1
Klatt, P.2
Vazquez, J.3
-
118
-
-
0347367072
-
Spatial redox regulation of a critical cysteine residue of NF-kappa B in vivo
-
Nishi T, Shimizu N, Hiramoto M, et al. Spatial redox regulation of a critical cysteine residue of NF-kappa B in vivo. J Biol Chem 2002; 277:44548-44556.
-
(2002)
J Biol Chem
, vol.277
, pp. 44548-44556
-
-
Nishi, T.1
Shimizu, N.2
Hiramoto, M.3
-
119
-
-
48349107170
-
A new APE1/Ref-1-dependent pathway leading to reduction of NF-kappaB and AP-1, and activation of their DNA-binding activity
-
Ando K, Hirao S, Kabe Y, et al. A new APE1/Ref-1-dependent pathway leading to reduction of NF-kappaB and AP-1, and activation of their DNA-binding activity. Nucleic Acids Res 2008; 36:4327-4336.
-
(2008)
Nucleic Acids Res
, vol.36
, pp. 4327-4336
-
-
Ando, K.1
Hirao, S.2
Kabe, Y.3
-
120
-
-
0029666293
-
Inhibition of NF-kappaB DNA binding by nitric oxide
-
Matthews JR, Botting CH, Panico M, Morris HR, Hay RT. Inhibition of NF-kappaB DNA binding by nitric oxide. Nucleic Acids Res 1996; 24:2236-2242.
-
(1996)
Nucleic Acids Res
, vol.24
, pp. 2236-2242
-
-
Matthews, J.R.1
Ch, B.2
Panico, M.3
Morris, H.R.4
Hay, R.T.5
-
122
-
-
44349176408
-
RelA Ser276 phosphorylation is required for activation of a subset of NF-kappaB-dependent genes by recruiting cyclin-dependent kinase 9/cyclin T1 complexes
-
Nowak DE, Tian B, Jamaluddin M, et al. RelA Ser276 phosphorylation is required for activation of a subset of NF-kappaB-dependent genes by recruiting cyclin-dependent kinase 9/cyclin T1 complexes. Mol Cell Biol 2008; 28:3623-3638.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 3623-3638
-
-
De, N.1
Tian, B.2
Jamaluddin, M.3
-
123
-
-
0036203419
-
The phosphorylation status of nuclear NF-kappa B determines its association with CBP/p300 or HDAC-1
-
Zhong H, May MJ, Jimi E, Ghosh S. The phosphorylation status of nuclear NF-kappa B determines its association with CBP/p300 or HDAC-1. Mol Cell 2002; 9:625-636.
-
(2002)
Mol Cell
, vol.9
, pp. 625-636
-
-
Zhong, H.1
May, M.J.2
Jimi, E.3
Ghosh, S.4
-
124
-
-
0032039076
-
Phosphorylation of NF-kappa B p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300
-
Zhong H, Voll RE, Ghosh S. Phosphorylation of NF-kappa B p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300. Mol Cell 1998; 1:661-671.
-
(1998)
Mol Cell
, vol.1
, pp. 661-671
-
-
Zhong, H.1
Voll, R.E.2
Ghosh, S.3
-
125
-
-
68949196898
-
Redox regulation of nuclear post-translational modifications during NF-kappaB activation
-
Gloire G, Piette J. Redox regulation of nuclear post-translational modifications during NF-kappaB activation. Antioxid Redox Signal 2009; 11:2209-2222.
-
(2009)
Antioxid Redox Signal
, vol.11
, pp. 2209-2222
-
-
Gloire, G.1
Piette, J.2
-
126
-
-
34249289745
-
TNFalpha-induced NF-kappaB/RelA Ser(276) phosphorylation and enhanceosome formation is mediated by an ROS-dependent PKAc pathway
-
Jamaluddin M, Wang S, Boldogh I, Tian B, Brasier AR. TNFalpha-induced NF-kappaB/RelA Ser(276) phosphorylation and enhanceosome formation is mediated by an ROS-dependent PKAc pathway. Cellular signalling 2007; 19:1419-1433.
-
(2007)
Cellular Signalling
, vol.19
, pp. 1419-1433
-
-
Jamaluddin, M.1
Wang, S.2
Boldogh, I.3
Tian, B.4
Brasier, A.R.5
-
127
-
-
49449093530
-
DNA-binding activity of NFkappaB and phosphorylation of p65 are induced by N-acetylcysteine through phosphatidylinositol (PI) 3-kinase
-
Liu J, Yoshida Y, Yamashita U. DNA-binding activity of NFkappaB and phosphorylation of p65 are induced by N-acetylcysteine through phosphatidylinositol (PI) 3-kinase. Mol Immunol 2008; 45:3984-3989.
-
(2008)
Mol Immunol
, vol.45
, pp. 3984-3989
-
-
Liu, J.1
Yoshida, Y.2
Yamashita, U.3
-
128
-
-
0027199115
-
Reactive oxygen intermediates activate NF-kappa B in a tyrosine kinase-dependent mechanism and in combination with vanadate activate the p56lck and p59fyn tyrosine kinases in human lymphocytes
-
Schieven GL, Kirihara JM, Myers DE, Ledbetter JA, Uckun FM. Reactive oxygen intermediates activate NF-kappa B in a tyrosine kinase-dependent mechanism and in combination with vanadate activate the p56lck and p59fyn tyrosine kinases in human lymphocytes. Blood 1993; 82:1212-1220.
-
(1993)
Blood
, vol.82
, pp. 1212-1220
-
-
Schieven, G.L.1
Kirihara, J.M.2
De, M.3
Ledbetter, J.A.4
Uckun, F.M.5
-
129
-
-
0034655179
-
Crucial role of the amino-terminal tyrosine residue 42 and the carboxyl-terminal PEST domain of i kappa B alpha in NFkappa B activation by an oxidative stress
-
Schoonbroodt S, Ferreira V, Best-Belpomme M, et al. Crucial role of the amino-terminal tyrosine residue 42 and the carboxyl-terminal PEST domain of I kappa B alpha in NFkappa B activation by an oxidative stress. J Immunol 2000; 164:4292-4300.
-
(2000)
J Immunol
, vol.164
, pp. 4292-4300
-
-
Schoonbroodt, S.1
Ferreira, V.2
Best-Belpomme, M.3
-
130
-
-
0037591401
-
Hydrogen peroxide activates NF-kappa B through tyrosine phosphorylation of i kappa B alpha and serine phosphorylation of p65: Evidence for the involvement of i kappa B alpha kinase and Syk protein-tyrosine kinase
-
Takada Y, Mukhopadhyay A, Kundu GC, et al. Hydrogen peroxide activates NF-kappa B through tyrosine phosphorylation of I kappa B alpha and serine phosphorylation of p65: evidence for the involvement of I kappa B alpha kinase and Syk protein-tyrosine kinase. J Biol Chem 2003; 278:24233-24241.
-
(2003)
J Biol Chem
, vol.278
, pp. 24233-24241
-
-
Takada, Y.1
Mukhopadhyay, A.2
Kundu, G.C.3
-
131
-
-
0345149546
-
Oxidative stress induces NF-kappaB nuclear translocation without degradation of IkappaBalpha
-
Canty TG Jr, Boyle EM, Jr., Farr A, et al. Oxidative stress induces NF-kappaB nuclear translocation without degradation of IkappaBalpha. Circulation 1999; 100(19 Suppl):II361-II364.
-
(1999)
Circulation
, vol.100
, Issue.19 SUPPL.
-
-
Canty Jr., T.G.1
Boyle Jr., E.M.2
Farr, A.3
-
132
-
-
0037449777
-
Tyrosine phosphorylation of i kappa B alpha activates NF kappa B through a redox-regulated and c-Src-dependent mechanism following hypoxia/reoxygenation
-
Fan C, Li Q, Ross D, Engelhardt JF. Tyrosine phosphorylation of I kappa B alpha activates NF kappa B through a redox-regulated and c-Src-dependent mechanism following hypoxia/reoxygenation. J Biol Chem 2003; 278:2072-2080.
-
(2003)
J Biol Chem
, vol.278
, pp. 2072-2080
-
-
Fan, C.1
Li, Q.2
Ross, D.3
Engelhardt, J.F.4
-
133
-
-
16044365828
-
Tyrosine phosphorylation of i kappa B-alpha activates NF-kappa B without proteolytic degradation of i kappa B-alpha
-
Imbert V, Rupec RA, Livolsi A, et al. Tyrosine phosphorylation of I kappa B-alpha activates NF-kappa B without proteolytic degradation of I kappa B-alpha. Cell 1996; 86:787-798.
-
(1996)
Cell
, vol.86
, pp. 787-798
-
-
Imbert, V.1
Rupec, R.A.2
Livolsi, A.3
-
134
-
-
34547616284
-
Dual role of mitochondrial reactive oxygen species in hypoxia signaling: Activation of nuclear factor-{kappa} B via c-SRC and oxidant-dependent cell death
-
Lluis JM, Buricchi F, Chiarugi P, Morales A, Fernandez-Checa JC. Dual role of mitochondrial reactive oxygen species in hypoxia signaling: activation of nuclear factor-{kappa} B via c-SRC and oxidant-dependent cell death. Cancer Res 2007; 67:7368-7377.
-
(2007)
Cancer Res
, vol.67
, pp. 7368-7377
-
-
Lluis, J.M.1
Buricchi, F.2
Chiarugi, P.3
Morales, A.4
Fernandez-Checa, J.C.5
-
135
-
-
0028268629
-
Hypoxia causes the activation of nuclear factor kappa B through the phosphorylation of i kappa B alpha on tyrosine residues
-
Koong AC, Chen EY, Giaccia AJ. Hypoxia causes the activation of nuclear factor kappa B through the phosphorylation of I kappa B alpha on tyrosine residues. Cancer Res 1994; 54:1425-1430.
-
(1994)
Cancer Res
, vol.54
, pp. 1425-1430
-
-
Koong, A.C.1
Chen, E.Y.2
Giaccia, A.J.3
-
136
-
-
0033582285
-
Involvement of regulatory and catalytic subunits of phosphoinositide 3-kinase in NFkappaB activation
-
Beraud C, Henzel WJ, Baeuerle PA. Involvement of regulatory and catalytic subunits of phosphoinositide 3-kinase in NFkappaB activation. Proc Natl Acad Sci USA 1999; 96:429-434.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 429-434
-
-
Beraud, C.1
Henzel, W.J.2
Baeuerle, P.A.3
-
137
-
-
85047689695
-
IkappaBalpha and IkappaBbeta possess injury context-specific functions that uniquely influence hepatic NF-kappaB induction and inflammation
-
Fan C, Li Q, Zhang Y, et al. IkappaBalpha and IkappaBbeta possess injury context-specific functions that uniquely influence hepatic NF-kappaB induction and inflammation. J Clin Invest 2004; 113:746-755.
-
(2004)
J Clin Invest
, vol.113
, pp. 746-755
-
-
Fan, C.1
Li, Q.2
Zhang, Y.3
-
138
-
-
65649142014
-
Reactive oxygen species mediate liver injury through parenchymal nuclear factorkappaB inactivation in prolonged ischemia/reperfusion
-
Llacuna L, Mari M, Lluis JM, et al. Reactive oxygen species mediate liver injury through parenchymal nuclear factorkappaB inactivation in prolonged ischemia/reperfusion. Am J Pathol 2009; 174:1776-1785.
-
(2009)
Am J Pathol
, vol.174
, pp. 1776-1785
-
-
Llacuna, L.1
Mari, M.2
Lluis, J.M.3
-
140
-
-
57449104348
-
Sustained oxidative stress inhibits NF-kappaB activation partially via inactivating the proteasome
-
Wu M, Bian Q, Liu Y, et al. Sustained oxidative stress inhibits NF-kappaB activation partially via inactivating the proteasome. Free Radic Biol Med 2009; 46:62-69.
-
(2009)
Free Radic Biol Med
, vol.46
, pp. 62-69
-
-
Wu, M.1
Bian, Q.2
Liu, Y.3
-
141
-
-
13244249801
-
Iron-mediated H2O2 production as a mechanism for cell type-specific inhibition of tumor necrosis factor alpha-induced but not interleukin-1beta- induced IkappaB kinase complex/nuclear factor-kappaB activation
-
Panopoulos A, Harraz M, Engelhardt JF, Zandi E. Iron-mediated H2O2 production as a mechanism for cell type-specific inhibition of tumor necrosis factor alpha-induced but not interleukin-1beta-induced IkappaB kinase complex/nuclear factor-kappaB activation. J Biol Chem 2005; 280:2912-2923.
-
(2005)
J Biol Chem
, vol.280
, pp. 2912-2923
-
-
Panopoulos, A.1
Harraz, M.2
Engelhardt, J.F.3
Zandi, E.4
-
142
-
-
33748339203
-
Dynamic redox control of NF-kappaB through glutaredoxin-regulated S-glutathionylation of inhibitory kappaB kinase beta
-
Reynaert NL, van der Vliet A, Guala AS, et al. Dynamic redox control of NF-kappaB through glutaredoxin-regulated S-glutathionylation of inhibitory kappaB kinase beta. Proc Natl Sci USA 2006; 103:13086-13091.
-
(2006)
Proc Natl Sci USA
, vol.103
, pp. 13086-13091
-
-
Reynaert, N.L.1
Van Der Vliet, A.2
Guala, A.S.3
-
143
-
-
0035929670
-
Cytokine-induced activation of nuclear factor-kappa B is inhibited by hydrogen peroxide through oxidative inactivation of IkappaB kinase
-
Korn SH, Wouters EF, Vos N, Janssen-Heininger YM. Cytokine-induced activation of nuclear factor-kappa B is inhibited by hydrogen peroxide through oxidative inactivation of IkappaB kinase. J Biol Chem 2001; 276:35693-35700.
-
(2001)
J Biol Chem
, vol.276
, pp. 35693-35700
-
-
Korn, S.H.1
Wouters, E.F.2
Vos, N.3
Janssen-Heininger, Y.M.4
-
144
-
-
0037202937
-
Dual effect of oxidative stress on NF-kappakB activation in HeLa cells
-
Byun MS, Jeon KI, Choi JW, Shim JY, Jue DM. Dual effect of oxidative stress on NF-kappakB activation in HeLa cells. Exp Mol Med 2002; 34:332-339.
-
(2002)
Exp Mol Med
, vol.34
, pp. 332-339
-
-
Byun, M.S.1
Jeon, K.I.2
Choi, J.W.3
Shim, J.Y.4
Jue, D.M.5
-
145
-
-
0034680928
-
Inhibition of NFkappa B activation by arsenite through reaction with a critical cysteine in the activation loop of Ikappa B kinase
-
Kapahi P, Takahashi T, Natoli G, et al. Inhibition of NFkappa B activation by arsenite through reaction with a critical cysteine in the activation loop of Ikappa B kinase. J Biol Chem 2000; 275:36062-36066.
-
(2000)
J Biol Chem
, vol.275
, pp. 36062-36066
-
-
Kapahi, P.1
Takahashi, T.2
Natoli, G.3
-
146
-
-
2942695715
-
Nitric oxide represses inhibitory kappaB kinase through S-nitrosylation
-
Reynaert NL, Ckless K, Korn SH, et al. Nitric oxide represses inhibitory kappaB kinase through S-nitrosylation. Proc Natl Acad Sci USA 2004; 101:8945-8950.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 8945-8950
-
-
Reynaert, N.L.1
Ckless, K.2
Korn, S.H.3
-
147
-
-
0034610759
-
Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of IkappaB kinase
-
Rossi A, Kapahi P, Natoli G, et al. Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of IkappaB kinase. Nature 2000; 403:103-108.
-
(2000)
Nature
, vol.403
, pp. 103-108
-
-
Rossi, A.1
Kapahi, P.2
Natoli, G.3
-
148
-
-
38049070287
-
Intermolecular disulfide bond formation in the NEMO dimer requires Cys54 and Cys347
-
Herscovitch M, Comb W, Ennis T, et al. Intermolecular disulfide bond formation in the NEMO dimer requires Cys54 and Cys347. Biochem Biophys Res Commun 2008; 367:103-108.
-
(2008)
Biochem Biophys Res Commun
, vol.367
, pp. 103-108
-
-
Herscovitch, M.1
Comb, W.2
Ennis, T.3
-
149
-
-
0034979924
-
Hydrogen peroxide has opposing effects on IKK activity and IkappaBalpha breakdown in airway epithelial cells
-
Jaspers I, Zhang W, Fraser A, Samet JM, Reed W. Hydrogen peroxide has opposing effects on IKK activity and IkappaBalpha breakdown in airway epithelial cells. Am J Respir Cell Mol Biol 2001; 24:769-777.
-
(2001)
Am J Respir Cell Mol Biol
, vol.24
, pp. 769-777
-
-
Jaspers, I.1
Zhang, W.2
Fraser, A.3
Samet, J.M.4
Reed, W.5
-
150
-
-
0037157177
-
Hydrogen peroxide activates IkappaB kinases through phosphorylation of serine residues in the activation loops
-
Kamata H, Manabe T, Oka S, Kamata K, Hirata H. Hydrogen peroxide activates IkappaB kinases through phosphorylation of serine residues in the activation loops. FEBS Lett 2002; 519:231-237.
-
(2002)
FEBS Lett
, vol.519
, pp. 231-237
-
-
Kamata, H.1
Manabe, T.2
Oka, S.3
Kamata, K.4
Hirata, H.5
-
151
-
-
16644387391
-
Thiol oxidation of cell signaling proteins: Controlling an apoptotic equilibrium
-
Cross JV, Templeton DJ. Thiol oxidation of cell signaling proteins: Controlling an apoptotic equilibrium. J Cell Biochem 2004; 93:104-111.
-
(2004)
J Cell Biochem
, vol.93
, pp. 104-111
-
-
Cross, J.V.1
Templeton, D.J.2
-
152
-
-
0034625170
-
MEK kinase 1 is critically required for c-Jun N-terminal kinase activation by proinflammatory stimuli and growth factor-induced cell migration
-
Xia Y, Makris C, Su B, et al. MEK kinase 1 is critically required for c-Jun N-terminal kinase activation by proinflammatory stimuli and growth factor-induced cell migration. Proc Natl Acad Sci USA 2000; 97:5243-5248.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 5243-5248
-
-
Xia, Y.1
Makris, C.2
Su, B.3
-
153
-
-
0034922161
-
The essential role of MEKK3 in TNF-induced NF-kappaB activation
-
Yang J, Lin Y, Guo Z, et al. The essential role of MEKK3 in TNF-induced NF-kappaB activation. Nat Immunol 2001; 2:620-624.
-
(2001)
Nat Immunol
, vol.2
, pp. 620-624
-
-
Yang, J.1
Lin, Y.2
Guo, Z.3
-
154
-
-
30044449755
-
TAK1 is recruited to the tumor necrosis factor-alpha (TNF-alpha) receptor 1 complex in a receptor-interacting protein (RIP)-dependent manner and cooperates with MEKK3 leading to NF-kappaB activation
-
Blonska M, Shambharkar PB, Kobayashi M, et al. TAK1 is recruited to the tumor necrosis factor-alpha (TNF-alpha) receptor 1 complex in a receptor-interacting protein (RIP)-dependent manner and cooperates with MEKK3 leading to NF-kappaB activation. J Biol Chem 2005; 280:43056-43063.
-
(2005)
J Biol Chem
, vol.280
, pp. 43056-43063
-
-
Blonska, M.1
Shambharkar, P.B.2
Kobayashi, M.3
-
155
-
-
32844460235
-
D-MEKK1, the Drosophila orthologue of mammalian MEKK4/MTK1, and Hemipterous/D-MKK7 mediate the activation of D-JNK by cadmium and arsenite in Schneider cells
-
Ryabinina OP, Subbian E, Iordanov MS. D-MEKK1, the Drosophila orthologue of mammalian MEKK4/MTK1, and Hemipterous/D-MKK7 mediate the activation of D-JNK by cadmium and arsenite in Schneider cells. BMC Cell Biol 2006; 7:7.
-
(2006)
BMC Cell Biol
, vol.7
, pp. 7
-
-
Ryabinina, O.P.1
Subbian, E.2
Iordanov, M.S.3
-
157
-
-
27744577296
-
TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo
-
Shim JH, Xiao C, Paschal AE, et al. TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo. Genes Dev 2005; 19:2668-2681.
-
(2005)
Genes Dev
, vol.19
, pp. 2668-2681
-
-
Shim, J.H.1
Xiao, C.2
Paschal, A.E.3
-
158
-
-
27544434183
-
Essential function for the kinase TAK1 in innate and adaptive immune responses
-
Sato S, Sanjo H, Takeda K, et al. Essential function for the kinase TAK1 in innate and adaptive immune responses. Nat Immunol 2005; 6:1087-1095.
-
(2005)
Nat Immunol
, vol.6
, pp. 1087-1095
-
-
Sato, S.1
Sanjo, H.2
Takeda, K.3
-
159
-
-
0037422858
-
TAK1 is critical for IkappaB kinase-mediated activation of the NF-kappaB pathway
-
Takaesu G, Surabhi RM, Park KJ, et al. TAK1 is critical for IkappaB kinase-mediated activation of the NF-kappaB pathway. J Mol Biol 2003; 326:105-115.
-
(2003)
J Mol Biol
, vol.326
, pp. 105-115
-
-
Takaesu, G.1
Surabhi, R.M.2
Park, K.J.3
-
160
-
-
33644990327
-
Interleukin-1beta induction of NFkappaB is partially regulated by H2O2-mediated activation of NFkappaB-inducing kinase
-
Li Q, Engelhardt JF. Interleukin-1beta induction of NFkappaB is partially regulated by H2O2-mediated activation of NFkappaB-inducing kinase. J Biol Chem 2006; 281:1495-1505.
-
(2006)
J Biol Chem
, vol.281
, pp. 1495-1505
-
-
Li, Q.1
Engelhardt, J.F.2
-
161
-
-
0035379555
-
Akt stimulates the transactivation potential of the RelA/p65 Subunit of NF-kappa B through utilization of the Ikappa B kinase and activation of the mitogen-activated protein kinase p38
-
Madrid LV, Mayo MW, Reuther JY, Baldwin AS Jr. Akt stimulates the transactivation potential of the RelA/p65 Subunit of NF-kappa B through utilization of the Ikappa B kinase and activation of the mitogen-activated protein kinase p38. J Biol Chem 2001; 276:18934-18940.
-
(2001)
J Biol Chem
, vol.276
, pp. 18934-18940
-
-
Madrid, L.V.1
Mayo, M.W.2
Reuther, J.Y.3
Baldwin Jr., A.S.4
-
162
-
-
44849117768
-
Akt-dependent regulation of NF-{kappa}B is controlled by mTOR and Raptor in association with IKK
-
Dan HC, Cooper MJ, Cogswell PC, et al. Akt-dependent regulation of NF-{kappa}B is controlled by mTOR and Raptor in association with IKK. Genes Dev 2008; 22:1490-1500.
-
(2008)
Genes Dev
, vol.22
, pp. 1490-1500
-
-
Dan, H.C.1
Cooper, M.J.2
Cogswell, P.C.3
-
163
-
-
0346749513
-
Glutaredoxin exerts an antiapoptotic effect by regulating the redox state of Akt
-
Murata H, Ihara Y, Nakamura H, et al. Glutaredoxin exerts an antiapoptotic effect by regulating the redox state of Akt. J Biol Chem 2003; 278:50226-50233.
-
(2003)
J Biol Chem
, vol.278
, pp. 50226-50233
-
-
Murata, H.1
Ihara, Y.2
Nakamura, H.3
-
164
-
-
0037036358
-
Reversible inactivation of the tumor suppressor PTEN by H2O2
-
Lee SR, Yang KS, Kwon J, et al. Reversible inactivation of the tumor suppressor PTEN by H2O2. J Biol Chem 2002; 277:20336-20342.
-
(2002)
J Biol Chem
, vol.277
, pp. 20336-20342
-
-
Lee, S.R.1
Yang, K.S.2
Kwon, J.3
|