GCN2 phosphorylation of eIF2α activates NF-κB in response to UV irradiation

Biochemical Journal

Volumn 385, Issue 2, 2005, Pages 371-380

  Jiang, Hao Yuan ^a   Wek, Ronald C ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Eukaryotic initiation factor 2 (eIF2); General control non derepressible 2 (GCN2); Nuclear factor B (NF B); Stress response; Translational Control; UV irradiation

Indexed keywords

CELL CULTURE; ENVIRONMENTAL IMPACT; GENES; PROTEINS; REMEDIATION; RNA;

APOPTOSIS; CELL PROLIFERATION; PHOSPHORYLATION; STRESS RESPONSE;

ULTRAVIOLET RADIATION;

GENERAL CONTROL NON DEREPRESSIBLE 2 PROTEIN; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INITIATION FACTOR 2ALPHA; PROTEIN KINASE; PROTEIN SUBUNIT; RNA DEPENDENT PROTEIN KINASE LIKE ENDOPLASMIC RETICULUM KINASE; SYNAPTOTAGMIN; TRANSCRIPTION FACTOR RELA; UNCLASSIFIED DRUG; ACTIVATING TRANSCRIPTION FACTOR 4; ATF4 PROTEIN, MOUSE; CCAAT ENHANCER BINDING PROTEIN; DDIT3 PROTEIN, MOUSE; EIF2AK4 PROTEIN, MOUSE; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; I KAPPA B; INITIATION FACTOR 2; PROTEIN KINASE R; PROTEIN SERINE THREONINE KINASE; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR; VIRUS T ANTIGEN;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DAMAGE; CELL PROLIFERATION; CELL REGENERATION; CONTROLLED STUDY; EMBRYO; ENDOPLASMIC RETICULUM; ENZYME PHOSPHORYLATION; GENE ACTIVATION; GENE EXPRESSION; MAMMAL CELL; MOUSE; NONHUMAN; NUCLEOCYTOPLASMIC TRANSPORT; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; PROTEIN TRANSPORT; RADIATION EXPOSURE; RADIATION RESPONSE; STRESS; TRANSCRIPTION REGULATION; ULTRAVIOLET B RADIATION; ULTRAVIOLET C RADIATION; ULTRAVIOLET RADIATION; ANIMAL; CELL CULTURE; CELL LINE; CHEMISTRY; CYTOLOGY; FIBROBLAST; GENETICS; METABOLISM; OXIDATIVE STRESS; PHOSPHORYLATION; VIROLOGY;

ANIMALIA; EUKARYOTA; MAMMALIA; MURINAE;

ACTIVATING TRANSCRIPTION FACTOR 4; ANIMALS; ANTIGENS, POLYOMAVIRUS TRANSFORMING; CCAAT-ENHANCER-BINDING PROTEINS; CELL LINE, TRANSFORMED; CELLS, CULTURED; EIF-2 KINASE; EMBRYO; ENDOPLASMIC RETICULUM; EUKARYOTIC INITIATION FACTOR-2; FIBROBLASTS; I-KAPPA B PROTEINS; MICE; NF-KAPPA B; OXIDATIVE STRESS; PHOSPHORYLATION; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; TRANS-ACTIVATORS; TRANSCRIPTION FACTOR CHOP; TRANSCRIPTION FACTORS; ULTRAVIOLET RAYS;

EID: 12844259491     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20041164     Document Type: Article

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