메뉴 건너뛰기




Volumn 95, Issue 2, 2015, Pages 377-404

The evolving impact of g protein-coupled receptor kinases in cardiac health and disease

Author keywords

[No Author keywords available]

Indexed keywords

BETA ARRESTIN; G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR KINASE; G PROTEIN COUPLED RECEPTOR KINASE 2; G PROTEIN COUPLED RECEPTOR KINASE 3; G PROTEIN COUPLED RECEPTOR KINASE 4; G PROTEIN COUPLED RECEPTOR KINASE 5;

EID: 84926611120     PISSN: 00319333     EISSN: 15221210     Source Type: Journal    
DOI: 10.1152/physrev.00015.2014     Document Type: Article
Times cited : (118)

References (285)
  • 2
    • 70350065897 scopus 로고    scopus 로고
    • Myocardial and peripheral lymphocytic transcriptomic dissociation of beta-adrenoceptors and G protein-coupled receptor kinases in heart transplantation
    • Aguero J, Almenar L, D’Ocon P, Oliver E, Monto F, Rueda J, Vicente D, Martinez-Dolz L, Salvador A. Myocardial and peripheral lymphocytic transcriptomic dissociation of beta-adrenoceptors and G protein-coupled receptor kinases in heart transplantation. J Heart Lung Transplant 28: 1166-1171, 2009
    • (2009) J Heart Lung Transplant , vol.28 , pp. 1166-1171
    • Aguero, J.1    Almenar, L.2    D’Ocon, P.3    Oliver, E.4    Monto, F.5    Rueda, J.6    Vicente, D.7    Martinez-Dolz, L.8    Salvador, A.9
  • 4
    • 39849085956 scopus 로고    scopus 로고
    • Altered expression and subcellular distribution of GRK subtypes in the dopamine-depleted rat basal ganglia is not normalized by L-DOPA treatment
    • Ahmed MR, Bychkov E, Gurevich VV, Benovic JL, Gurevich EV. Altered expression and subcellular distribution of GRK subtypes in the dopamine-depleted rat basal ganglia is not normalized by L-DOPA treatment. J Neurochem 104: 1622-1636, 2008
    • (2008) J Neurochem , vol.104 , pp. 1622-1636
    • Ahmed, M.R.1    Bychkov, E.2    Gurevich, V.V.3    Benovic, J.L.4    Gurevich, E.V.5
  • 7
    • 0032897297 scopus 로고    scopus 로고
    • The myocardial beta-adrenergic system in spontaneously hypertensive heart failure (SHHF) rats
    • Anderson KM, Eckhart AD, Willette RN, Koch WJ. The myocardial beta-adrenergic system in spontaneously hypertensive heart failure (SHHF) rats. Hypertension 33: 402-407, 1999
    • (1999) Hypertension , vol.33 , pp. 402-407
    • Anderson, K.M.1    Eckhart, A.D.2    Willette, R.N.3    Koch, W.J.4
  • 8
    • 0028174033 scopus 로고
    • Fingerprinting G-protein-coupled receptors
    • Attwood TK, Findlay JB. Fingerprinting G-protein-coupled receptors. Protein Eng 7: 195-203, 1994
    • (1994) Protein Eng , vol.7 , pp. 195-203
    • Attwood, T.K.1    Findlay, J.B.2
  • 10
    • 77149143842 scopus 로고    scopus 로고
    • Role for the regulator of G-protein signaling homology domain of G protein-coupled receptor kinases 5 and 6 in beta 2-adrenergic receptor and rhodopsin phosphorylation
    • Baameur F, Morgan DH, Yao H, Tran TM, Hammitt RA, Sabui S, McMurray JS, Lichtarge O, Clark RB. Role for the regulator of G-protein signaling homology domain of G protein-coupled receptor kinases 5 and 6 in beta 2-adrenergic receptor and rhodopsin phosphorylation. Mol Pharmacol 77: 405-415, 2010
    • (2010) Mol Pharmacol , vol.77 , pp. 405-415
    • Baameur, F.1    Morgan, D.H.2    Yao, H.3    Tran, T.M.4    Hammitt, R.A.5    Sabui, S.6    McMurray, J.S.7    Lichtarge, O.8    Clark, R.B.9
  • 12
    • 0037352887 scopus 로고    scopus 로고
    • Desensitization of alpha 2Aadrenoceptor signalling by modest levels of adrenaline is facilitated by beta 2-adrenoceptor-dependent GRK3 up-regulation
    • Bawa T, Altememi GF, Eikenburg DC, Standifer KM. Desensitization of alpha 2Aadrenoceptor signalling by modest levels of adrenaline is facilitated by beta 2-adrenoceptor-dependent GRK3 up-regulation. Br J Pharmacol 138: 921-931, 2003
    • (2003) Br J Pharmacol , vol.138 , pp. 921-931
    • Bawa, T.1    Altememi, G.F.2    Eikenburg, D.C.3    Standifer, K.M.4
  • 13
    • 4544228457 scopus 로고    scopus 로고
    • Functions of NF-kappaB1 and NF-kappaB2 in immune cell biology
    • Beinke S, Ley SC. Functions of NF-kappaB1 and NF-kappaB2 in immune cell biology. Biochem J 382: 393-409, 2004
    • (2004) Biochem J , vol.382 , pp. 393-409
    • Beinke, S.1    Ley, S.C.2
  • 14
    • 79961074094 scopus 로고    scopus 로고
    • G protein coupled receptor kinases as therapeutic targets in cardiovascular disease
    • Belmonte SL, Blaxall BC. G protein coupled receptor kinases as therapeutic targets in cardiovascular disease. Circ Res 109: 309-319, 2011
    • (2011) Circ Res , vol.109 , pp. 309-319
    • Belmonte, S.L.1    Blaxall, B.C.2
  • 15
    • 0036892794 scopus 로고    scopus 로고
    • Genotyping of essential hypertension single-nucleotide polymorphisms by a homogeneous PCR method with universal energy transfer primers
    • Bengra C, Mifflin TE, Khripin Y, Manunta P, Williams SM, Jose PA, Felder RA. Genotyping of essential hypertension single-nucleotide polymorphisms by a homogeneous PCR method with universal energy transfer primers. Clin Chem 48: 2131-2140, 2002
    • (2002) Clin Chem , vol.48 , pp. 2131-2140
    • Bengra, C.1    Mifflin, T.E.2    Khripin, Y.3    Manunta, P.4    Williams, S.M.5    Jose, P.A.6    Felder, R.A.7
  • 16
    • 0024412926 scopus 로고
    • Beta-adrenergic receptor kinase: Primary structure delineates a multigene family
    • Benovic JL, DeBlasi A, Stone WC, Caron MG, Lefkowitz RJ. Beta-adrenergic receptor kinase: primary structure delineates a multigene family. Science 246: 235-240, 1989
    • (1989) Science , vol.246 , pp. 235-240
    • Benovic, J.L.1    Deblasi, A.2    Stone, W.C.3    Caron, M.G.4    Lefkowitz, R.J.5
  • 17
    • 0027203962 scopus 로고
    • Molecular cloning and expression of GRK6. A new member of the G protein-coupled receptor kinase family
    • Benovic JL, Gomez J. Molecular cloning and expression of GRK6. A new member of the G protein-coupled receptor kinase family. J Biol Chem 268: 19521-19527, 1993
    • (1993) J Biol Chem , vol.268 , pp. 19521-19527
    • Benovic, J.L.1    Gomez, J.2
  • 18
    • 0022641020 scopus 로고
    • Light-dependent phosphorylation of rhodopsin by beta-adrenergic receptor kinase
    • Benovic JL, Mayor F Jr, Somers RL, Caron MG, Lefkowitz RJ. Light-dependent phosphorylation of rhodopsin by beta-adrenergic receptor kinase. Nature 321: 869-872, 1986
    • (1986) Nature , vol.321 , pp. 869-872
    • Benovic, J.L.1    Mayor, F.2    Somers, R.L.3    Caron, M.G.4    Lefkowitz, R.J.5
  • 21
    • 0344812247 scopus 로고
    • Beta-adrenergic receptor kinase: Identification of a novel protein kinase that phosphorylates the agonist-occupied form of the receptor
    • Benovic JL, Strasser RH, Caron MG, Lefkowitz RJ. Beta-adrenergic receptor kinase: identification of a novel protein kinase that phosphorylates the agonist-occupied form of the receptor. Proc Natl Acad Sci USA 83: 2797-2801, 1986
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 2797-2801
    • Benovic, J.L.1    Strasser, R.H.2    Caron, M.G.3    Lefkowitz, R.J.4
  • 22
    • 0025024267 scopus 로고
    • Light activation of one rhodopsin molecule causes the phosphorylation of hundreds of others. A reaction observed in electropermeabilized frog rod outer segments exposed to dim illumination
    • Binder BM, Biernbaum MS, Bownds MD. Light activation of one rhodopsin molecule causes the phosphorylation of hundreds of others. A reaction observed in electropermeabilized frog rod outer segments exposed to dim illumination. J Biol Chem 265: 15333-15340, 1990
    • (1990) J Biol Chem , vol.265 , pp. 15333-15340
    • Binder, B.M.1    Biernbaum, M.S.2    Bownds, M.D.3
  • 23
    • 0029786822 scopus 로고    scopus 로고
    • Phosphorylation of nonbleached rhodopsin in intact retinas and living frogs
    • Binder BM, O’Connor TM, Bownds MD, Arshavsky VY. Phosphorylation of nonbleached rhodopsin in intact retinas and living frogs. J Biol Chem 271: 19826-19830, 1996
    • (1996) J Biol Chem , vol.271 , pp. 19826-19830
    • Binder, B.M.1    O’Connor, T.M.2    Bownds, M.D.3    Arshavsky, V.Y.4
  • 24
    • 0037192823 scopus 로고    scopus 로고
    • Signaling molecules of the NF-kappa B pathway shuttle constitutively between cytoplasm and nucleus
    • Birbach A, Gold P, Binder BR, Hofer E, de Martin R, Schmid JA. Signaling molecules of the NF-kappa B pathway shuttle constitutively between cytoplasm and nucleus. J Biol Chem 277: 10842-10851, 2002
    • (2002) J Biol Chem , vol.277 , pp. 10842-10851
    • Birbach, A.1    Gold, P.2    Binder, B.R.3    Hofer, E.4    De Martin, R.5    Schmid, J.A.6
  • 26
    • 77957778459 scopus 로고    scopus 로고
    • Molecular basis for activation of G proteincoupled receptor kinases
    • Boguth CA, Singh P, Huang CC, Tesmer JJ. Molecular basis for activation of G proteincoupled receptor kinases. EMBO J 29: 3249-3259, 2010
    • (2010) EMBO J , vol.29 , pp. 3249-3259
    • Boguth, C.A.1    Singh, P.2    Huang, C.C.3    Tesmer, J.J.4
  • 27
    • 84873168698 scopus 로고    scopus 로고
    • The role of G protein coupled receptor kinases in neurocardiovascular pathophysiology
    • Bojic T, Sudar E, Mikhailidis D, Alavantic D, Isenovic E. The role of G protein coupled receptor kinases in neurocardiovascular pathophysiology. Arch Med Sci 8: 970-977, 2012
    • (2012) Arch Med Sci , vol.8 , pp. 970-977
    • Bojic, T.1    Sudar, E.2    Mikhailidis, D.3    Alavantic, D.4    Isenovic, E.5
  • 28
    • 0015521772 scopus 로고
    • Phosphorylation of frog photoreceptor membranes induced by light
    • Bownds D, Dawes J, Miller J, Stahlman M. Phosphorylation of frog photoreceptor membranes induced by light. Nat New Biol 237: 125-127, 1972
    • (1972) Nat New Biol , vol.237 , pp. 125-127
    • Bownds, D.1    Dawes, J.2    Miller, J.3    Stahlman, M.4
  • 29
    • 0032856787 scopus 로고    scopus 로고
    • Expression of G-proteincoupled receptor kinases in pregnant term and non-pregnant human myometrium
    • Brenninkmeijer CB, Price SA, Lopez Bernal A, Phaneuf S. Expression of G-proteincoupled receptor kinases in pregnant term and non-pregnant human myometrium. J Endocrinol 162: 401-408, 1999
    • (1999) J Endocrinol , vol.162 , pp. 401-408
    • Brenninkmeijer, C.B.1    Price, S.A.2    Lopez Bernal, A.3    Phaneuf, S.4
  • 32
    • 84883288744 scopus 로고    scopus 로고
    • Grk5l controls heart development by limiting mTOR signaling during symmetry breaking
    • Burkhalter MD, Fralish GB, Premont RT, Caron MG, Philipp M. Grk5l controls heart development by limiting mTOR signaling during symmetry breaking. Cell Rep 4: 625-632, 2013
    • (2013) Cell Rep , vol.4 , pp. 625-632
    • Burkhalter, M.D.1    Fralish, G.B.2    Premont, R.T.3    Caron, M.G.4    Philipp, M.5
  • 33
    • 38949138075 scopus 로고    scopus 로고
    • Arrestins and two receptor kinases are upregulated in Parkinson’s disease with dementia
    • Bychkov ER, Gurevich VV, Joyce JN, Benovic JL, Gurevich EV. Arrestins and two receptor kinases are upregulated in Parkinson’s disease with dementia. Neurobiol Aging 29: 379-396, 2008
    • (2008) Neurobiol Aging , vol.29 , pp. 379-396
    • Bychkov, E.R.1    Gurevich, V.V.2    Joyce, J.N.3    Benovic, J.L.4    Gurevich, E.V.5
  • 35
    • 0032101983 scopus 로고    scopus 로고
    • G-protein-coupled receptors: Turn-ons and turn-offs
    • Carman CV, Benovic JL. G-protein-coupled receptors: turn-ons and turn-offs. Curr Opin Neurobiol 8: 335-344, 1998
    • (1998) Curr Opin Neurobiol , vol.8 , pp. 335-344
    • Carman, C.V.1    Benovic, J.L.2
  • 37
    • 0032493759 scopus 로고    scopus 로고
    • Binding and phosphorylation of tubulin by G protein-coupled receptor kinases
    • Carman CV, Som T, Kim CM, Benovic JL. Binding and phosphorylation of tubulin by G protein-coupled receptor kinases. J Biol Chem 273: 20308-20316, 1998
    • (1998) J Biol Chem , vol.273 , pp. 20308-20316
    • Carman, C.V.1    Som, T.2    Kim, C.M.3    Benovic, J.L.4
  • 38
    • 0036688175 scopus 로고    scopus 로고
    • The use of constitutively active GPCRs in drug discovery and functional genomics
    • Chalmers DT, Behan DP. The use of constitutively active GPCRs in drug discovery and functional genomics. Nat Rev Drug Discov 1: 599-608, 2002
    • (2002) Nat Rev Drug Discov , vol.1 , pp. 599-608
    • Chalmers, D.T.1    Behan, D.P.2
  • 40
    • 0028978240 scopus 로고
    • Ca2+-dependent interaction of recoverin with rhodopsin kinase
    • Chen CK, Inglese J, Lefkowitz RJ, Hurley JB. Ca2+-dependent interaction of recoverin with rhodopsin kinase. J Biol Chem 270: 18060-18066, 1995
    • (1995) J Biol Chem , vol.270 , pp. 18060-18066
    • Chen, C.K.1    Inglese, J.2    Lefkowitz, R.J.3    Hurley, J.B.4
  • 42
    • 0027415931 scopus 로고
    • Beta-adrenergic receptor kinase. Agonistdependent receptor binding promotes kinase activation
    • Chen CY, Dion SB, Kim CM, Benovic JL. Beta-adrenergic receptor kinase. Agonistdependent receptor binding promotes kinase activation. J Biol Chem 268: 7825-7831, 1993
    • (1993) J Biol Chem , vol.268 , pp. 7825-7831
    • Chen, C.Y.1    Dion, S.B.2    Kim, C.M.3    Benovic, J.L.4
  • 43
    • 84876413668 scopus 로고    scopus 로고
    • Prodeath signaling of G protein-coupled receptor kinase 2 in cardiac myocytes after ischemic stress occurs via extracellular signal-regulated kinase-dependent heat shock protein 90-mediated mitochondrial targeting
    • Chen M, Sato PY, Chuprun JK, Peroutka RJ, Otis NJ, Ibetti J, Pan S, Sheu SS, Gao E, Koch WJ. Prodeath signaling of G protein-coupled receptor kinase 2 in cardiac myocytes after ischemic stress occurs via extracellular signal-regulated kinase-dependent heat shock protein 90-mediated mitochondrial targeting. Circ Res 112: 1121-1134, 2013
    • (2013) Circ Res , vol.112 , pp. 1121-1134
    • Chen, M.1    Sato, P.Y.2    Chuprun, J.K.3    Peroutka, R.J.4    Otis, N.J.5    Ibetti, J.6    Pan, S.7    Sheu, S.S.8    Gao, E.9    Koch, W.J.10
  • 44
    • 0035964801 scopus 로고    scopus 로고
    • Upregulation of functional beta(3)-adrenergic receptor in the failing canine myocardium
    • Cheng HJ, Zhang ZS, Onishi K, Ukai T, Sane DC, Cheng CP. Upregulation of functional beta(3)-adrenergic receptor in the failing canine myocardium. Circ Res 89: 599-606, 2001
    • (2001) Circ Res , vol.89 , pp. 599-606
    • Cheng, H.J.1    Zhang, Z.S.2    Onishi, K.3    Ukai, T.4    Sane, D.C.5    Cheng, C.P.6
  • 47
    • 0030798818 scopus 로고    scopus 로고
    • Mechanism of beta-adrenergic receptor desensitization in cardiac hypertrophy is increased beta-adrenergic receptor kinase
    • Choi DJ, Koch WJ, Hunter JJ, Rockman HA. Mechanism of beta-adrenergic receptor desensitization in cardiac hypertrophy is increased beta-adrenergic receptor kinase. J Biol Chem 272: 17223-17229, 1997
    • (1997) J Biol Chem , vol.272 , pp. 17223-17229
    • Choi, D.J.1    Koch, W.J.2    Hunter, J.J.3    Rockman, H.A.4
  • 48
    • 0029635377 scopus 로고
    • Phosphorylation and activation of beta-adrenergic receptor kinase by protein kinase C
    • Chuang TT, LeVine H 3rd, De Blasi A. Phosphorylation and activation of beta-adrenergic receptor kinase by protein kinase C. J Biol Chem 270: 18660-18665, 1995
    • (1995) J Biol Chem , vol.270 , pp. 18660-18665
    • Chuang, T.T.1    Levine, H.2    De Blasi, A.3
  • 49
    • 0001616166 scopus 로고    scopus 로고
    • Inhibition of G protein-coupled receptor kinase subtypes by Ca2+/calmodulin
    • Chuang TT, Paolucci L, De Blasi A. Inhibition of G protein-coupled receptor kinase subtypes by Ca2+/calmodulin. J Biol Chem 271: 28691-28696, 1996
    • (1996) J Biol Chem , vol.271 , pp. 28691-28696
    • Chuang, T.T.1    Paolucci, L.2    De Blasi, A.3
  • 53
    • 67649842618 scopus 로고    scopus 로고
    • G proteincoupled receptor kinase 2 expression and activity are associated with blood pressure in black Americans
    • Cohn HI, Xi Y, Pesant S, Harris DM, Hyslop T, Falkner B, Eckhart AD. G proteincoupled receptor kinase 2 expression and activity are associated with blood pressure in black Americans. Hypertension 54: 71-76, 2009
    • (2009) Hypertension , vol.54 , pp. 71-76
    • Cohn, H.I.1    Xi, Y.2    Pesant, S.3    Harris, D.M.4    Hyslop, T.5    Falkner, B.6    Eckhart, A.D.7
  • 54
    • 0035805528 scopus 로고    scopus 로고
    • Regulation of membrane targeting of the G protein-coupled receptor kinase 2 by protein kinase A and its anchoring protein AKAP79
    • Cong M, Perry SJ, Lin FT, Fraser ID, Hu LA, Chen W, Pitcher JA, Scott JD, Lefkowitz RJ. Regulation of membrane targeting of the G protein-coupled receptor kinase 2 by protein kinase A and its anchoring protein AKAP79. J Biol Chem 276: 15192-15199, 2001
    • (2001) J Biol Chem , vol.276 , pp. 15192-15199
    • Cong, M.1    Perry, S.J.2    Lin, F.T.3    Fraser, I.D.4    Hu, L.A.5    Chen, W.6    Pitcher, J.A.7    Scott, J.D.8    Lefkowitz, R.J.9
  • 55
    • 50049097448 scopus 로고    scopus 로고
    • Intrinsic disorder in scaffold proteins: Getting more from less
    • Cortese MS, Uversky VN, Dunker AK. Intrinsic disorder in scaffold proteins: getting more from less. Prog Biophys Mol Biol 98: 85-106, 2008
    • (2008) Prog Biophys Mol Biol , vol.98 , pp. 85-106
    • Cortese, M.S.1    Uversky, V.N.2    Dunker, A.K.3
  • 57
    • 0036428982 scopus 로고    scopus 로고
    • GRK3 regulation during CRF-and urocortin-induced CRF1 receptor desensitization
    • Dautzenberg FM, Wille S, Braun S, Hauger RL. GRK3 regulation during CRF-and urocortin-induced CRF1 receptor desensitization. Biochem Biophys Res Commun 298: 303-308, 2002
    • (2002) Biochem Biophys Res Commun , vol.298 , pp. 303-308
    • Dautzenberg, F.M.1    Wille, S.2    Braun, S.3    Hauger, R.L.4
  • 59
    • 0028985273 scopus 로고
    • Regulation of G protein-coupled receptor kinase subtypes in activated T lymphocytes. Selective increase of beta-adrenergic receptor kinase 1 and 2
    • De Blasi A, Parruti G, Sallese M. Regulation of G protein-coupled receptor kinase subtypes in activated T lymphocytes. Selective increase of beta-adrenergic receptor kinase 1 and 2. J Clin Invest 95: 203-210, 1995
    • (1995) J Clin Invest , vol.95 , pp. 203-210
    • De Blasi, A.1    Parruti, G.2    Sallese, M.3
  • 60
    • 0029788099 scopus 로고    scopus 로고
    • G protein-coupled receptor kinase GRK2 is a phospholipid-dependent enzyme that can be conditionally activated by G protein betagamma subunits
    • DebBurman SK, Ptasienski J, Benovic JL, Hosey MM. G protein-coupled receptor kinase GRK2 is a phospholipid-dependent enzyme that can be conditionally activated by G protein betagamma subunits. J Biol Chem 271: 22552-22562, 1996
    • (1996) J Biol Chem , vol.271 , pp. 22552-22562
    • Debburman, S.K.1    Ptasienski, J.2    Benovic, J.L.3    Hosey, M.M.4
  • 62
    • 77957372042 scopus 로고    scopus 로고
    • Beta3-adrenergic receptors in cardiac and vascular tissues emerging concepts and therapeutic perspectives
    • Dessy C, Balligand JL. Beta3-adrenergic receptors in cardiac and vascular tissues emerging concepts and therapeutic perspectives. Adv Pharmacol 59: 135-163, 2010
    • (2010) Adv Pharmacol , vol.59 , pp. 135-163
    • Dessy, C.1    Balligand, J.L.2
  • 63
    • 0037067705 scopus 로고    scopus 로고
    • Phosphorylationindependent regulation of metabotropic glutamate receptor signaling by G proteincoupled receptor kinase 2
    • Dhami GK, Anborgh PH, Dale LB, Sterne-Marr R, Ferguson SS. Phosphorylationindependent regulation of metabotropic glutamate receptor signaling by G proteincoupled receptor kinase 2. J Biol Chem 277: 25266-25272, 2002
    • (2002) J Biol Chem , vol.277 , pp. 25266-25272
    • Dhami, G.K.1    Anborgh, P.H.2    Dale, L.B.3    Sterne-Marr, R.4    Ferguson, S.S.5
  • 64
    • 1942501582 scopus 로고    scopus 로고
    • G Protein-coupled receptor kinase 2 regulator of G protein signaling homology domain binds to both metabotropic glutamate receptor 1a and Galphaq to attenuate signaling
    • Dhami GK, Dale LB, Anborgh PH, O’Connor-Halligan KE, Sterne-Marr R, Ferguson SS. G Protein-coupled receptor kinase 2 regulator of G protein signaling homology domain binds to both metabotropic glutamate receptor 1a and Galphaq to attenuate signaling. J Biol Chem 279: 16614-16620, 2004
    • (2004) J Biol Chem , vol.279 , pp. 16614-16620
    • Dhami, G.K.1    Dale, L.B.2    Anborgh, P.H.3    O’connor-Halligan, K.E.4    Sterne-Marr, R.5    Ferguson, S.S.6
  • 65
  • 67
    • 1942453389 scopus 로고    scopus 로고
    • Differential functional expression of human myocardial G protein receptor kinases in left ventricular cardiac diseases
    • Dzimiri N, Muiya P, Andres E, Al-Halees Z. Differential functional expression of human myocardial G protein receptor kinases in left ventricular cardiac diseases. Eur J Pharmacol 489: 167-177, 2004
    • (2004) Eur J Pharmacol , vol.489 , pp. 167-177
    • Dzimiri, N.1    Muiya, P.2    Res, E.3    Al-Halees, Z.4
  • 68
    • 0033982570 scopus 로고    scopus 로고
    • Hybrid transgenic mice reveal in vivo specificity ofGprotein-coupled receptor kinases in the heart
    • Eckhart AD, Duncan SJ, Penn RB, Benovic JL, Lefkowitz RJ, Koch WJ. Hybrid transgenic mice reveal in vivo specificity ofGprotein-coupled receptor kinases in the heart. Circ Res 86: 43-50, 2000
    • (2000) Circ Res , vol.86 , pp. 43-50
    • Eckhart, A.D.1    Duncan, S.J.2    Penn, R.B.3    Benovic, J.L.4    Lefkowitz, R.J.5    Koch, W.J.6
  • 69
    • 0036209075 scopus 로고    scopus 로고
    • Vascular-targeted overexpression of G protein-coupled receptor kinase-2 in transgenic mice attenuates beta-adrenergic receptor signaling and increases resting blood pressure
    • Eckhart AD, Ozaki T, Tevaearai H, Rockman HA, Koch WJ. Vascular-targeted overexpression of G protein-coupled receptor kinase-2 in transgenic mice attenuates beta-adrenergic receptor signaling and increases resting blood pressure. Mol Pharmacol 61: 749-758, 2002
    • (2002) Mol Pharmacol , vol.61 , pp. 749-758
    • Eckhart, A.D.1    Ozaki, T.2    Tevaearai, H.3    Rockman, H.A.4    Koch, W.J.5
  • 70
    • 0037424294 scopus 로고    scopus 로고
    • The amino-terminal domain of G-protein-coupled receptor kinase 2 is a regulatory Gbeta gamma binding site
    • Eichmann T, Lorenz K, Hoffmann M, Brockmann J, Krasel C, Lohse MJ, Quitterer U. The amino-terminal domain of G-protein-coupled receptor kinase 2 is a regulatory Gbeta gamma binding site. J Biol Chem 278: 8052-8057, 2003
    • (2003) J Biol Chem , vol.278 , pp. 8052-8057
    • Eichmann, T.1    Lorenz, K.2    Hoffmann, M.3    Brockmann, J.4    Krasel, C.5    Lohse, M.J.6    Quitterer, U.7
  • 71
    • 0042707658 scopus 로고    scopus 로고
    • MAPK-dependent degradation ofGproteincoupled receptor kinase 2
    • Elorza A, Penela P, Sarnago S, Mayor F Jr. MAPK-dependent degradation ofGproteincoupled receptor kinase 2. J Biol Chem 278: 29164-29173, 2003
    • (2003) J Biol Chem , vol.278 , pp. 29164-29173
    • Elorza, A.1    Penela, P.2    Sarnago, S.3    Mayor, F.4
  • 75
    • 33745411476 scopus 로고    scopus 로고
    • Molecular cloning of two rat GRK6 splice variants
    • Firsov D, Elalouf JM. Molecular cloning of two rat GRK6 splice variants. Am J Physiol Cell Physiol 273: C953-C961, 1997
    • (1997) Am J Physiol Cell Physiol , vol.273 , pp. C953-C961
    • Firsov, D.1    Elalouf, J.M.2
  • 78
    • 0038024615 scopus 로고    scopus 로고
    • The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints
    • Fredriksson R, Lagerstrom MC, Lundin LG, Schioth HB. The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints. Mol Pharmacol 63: 1256-1272, 2003
    • (2003) Mol Pharmacol , vol.63 , pp. 1256-1272
    • Fredriksson, R.1    Lagerstrom, M.C.2    Lundin, L.G.3    Schioth, H.B.4
  • 80
    • 0034685851 scopus 로고    scopus 로고
    • α-Actinin is a potent regulator of G protein-coupled receptor kinase activity and substrate specificity in vitro
    • Freeman JL, Pitcher JA, Li X, Bennett V, Lefkowitz RJ. α-Actinin is a potent regulator of G protein-coupled receptor kinase activity and substrate specificity in vitro. FEBS Lett 473: 280-284, 2000
    • (2000) FEBS Lett , vol.473 , pp. 280-284
    • Freeman, J.L.1    Pitcher, J.A.2    Li, X.3    Bennett, V.4    Lefkowitz, R.J.5
  • 87
    • 0036234459 scopus 로고    scopus 로고
    • Missing pieces in the NF-kappaB puzzle
    • Ghosh S, Karin M. Missing pieces in the NF-kappaB puzzle. Cell 109 Suppl: S81-96, 2002
    • (2002) Cell , vol.109 , pp. S81-S96
    • Ghosh, S.1    Karin, M.2
  • 88
    • 70449700143 scopus 로고    scopus 로고
    • Caveolin-1 and dopamine-mediated internalization of NaKATPase in human renal proximal tubule cells
    • Gildea JJ, Israel JA, Johnson AK, Zhang J, Jose PA, Felder RA. Caveolin-1 and dopamine-mediated internalization of NaKATPase in human renal proximal tubule cells. Hypertension 54: 1070-1076, 2009
    • (2009) Hypertension , vol.54 , pp. 1070-1076
    • Gildea, J.J.1    Israel, J.A.2    Johnson, A.K.3    Zhang, J.4    Jose, P.A.5    Felder, R.A.6
  • 89
    • 84867033583 scopus 로고    scopus 로고
    • Determining the absolute requirement of G protein-coupled receptor kinase 5 for pathological cardiac hypertrophy: Short communication
    • Gold JI, Gao E, Shang X, Premont RT, Koch WJ. Determining the absolute requirement of G protein-coupled receptor kinase 5 for pathological cardiac hypertrophy: short communication. Circ Res 111: 1048-1053, 2012
    • (2012) Circ Res , vol.111 , pp. 1048-1053
    • Gold, J.I.1    Gao, E.2    Shang, X.3    Premont, R.T.4    Koch, W.J.5
  • 92
    • 0031000256 scopus 로고    scopus 로고
    • G-protein-coupled receptor kinase activity is increased in hypertension
    • Gros R, Benovic JL, Tan CM, Feldman RD. G-protein-coupled receptor kinase activity is increased in hypertension. J Clin Invest 99: 2087-2093, 1997
    • (1997) J Clin Invest , vol.99 , pp. 2087-2093
    • Gros, R.1    Benovic, J.L.2    Tan, C.M.3    Feldman, R.D.4
  • 93
    • 0033954751 scopus 로고    scopus 로고
    • G-protein-coupled receptor kinase activity in hypertension: Increased vascular and lymphocyte G-protein receptor kinase-2 protein expression
    • Gros R, Chorazyczewski J, Meek MD, Benovic JL, Ferguson SS, Feldman RD. G-protein-coupled receptor kinase activity in hypertension: increased vascular and lymphocyte G-protein receptor kinase-2 protein expression. Hypertension 35: 38-42, 2000
    • (2000) Hypertension , vol.35 , pp. 38-42
    • Gros, R.1    Chorazyczewski, J.2    Meek, M.D.3    Benovic, J.L.4    Ferguson, S.S.5    Feldman, R.D.6
  • 95
    • 83555168220 scopus 로고    scopus 로고
    • G protein-coupled receptor kinases: More than just kinases and not only for GPCRs
    • Gurevich EV, Tesmer JJ, Mushegian A, Gurevich VV. G protein-coupled receptor kinases: more than just kinases and not only for GPCRs. Pharmacol Ther 133: 40-69, 2012
    • (2012) Pharmacol Ther , vol.133 , pp. 40-69
    • Gurevich, E.V.1    Tesmer, J.J.2    Mushegian, A.3    Gurevich, V.V.4
  • 96
    • 0032528248 scopus 로고    scopus 로고
    • GTP-binding-protein-coupled receptor kinase 2 (GRK2) binds and phosphorylates tubulin
    • Haga K, Ogawa H, Haga T, Murofushi H. GTP-binding-protein-coupled receptor kinase 2 (GRK2) binds and phosphorylates tubulin. Eur J Biochem 255: 363-368, 1998
    • (1998) Eur J Biochem , vol.255 , pp. 363-368
    • Haga, K.1    Ogawa, H.2    Haga, T.3    Murofushi, H.4
  • 97
    • 0035826710 scopus 로고    scopus 로고
    • Cardiac beta ARK1 inhibition prolongs survival and augments beta blocker therapy in a mouse model of severe heart failure
    • Harding VB, Jones LR, Lefkowitz RJ, Koch WJ, Rockman HA. Cardiac beta ARK1 inhibition prolongs survival and augments beta blocker therapy in a mouse model of severe heart failure. Proc Natl Acad Sci USA 98: 5809-5814, 2001
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 5809-5814
    • Harding, V.B.1    Jones, L.R.2    Lefkowitz, R.J.3    Koch, W.J.4    Rockman, H.A.5
  • 98
    • 0027504450 scopus 로고
    • Identification of additional members of human G-proteincoupled receptor kinase multigene family
    • Haribabu B, Snyderman R. Identification of additional members of human G-proteincoupled receptor kinase multigene family. Proc Natl Acad Sci USA 90: 9398-9402, 1993
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 9398-9402
    • Haribabu, B.1    Snyderman, R.2
  • 100
    • 33744533073 scopus 로고    scopus 로고
    • Lymphocyte levels of GRK2 (BetaARK1) mirror changes in the LVAD-supported failing human heart: Lower GRK2 associated with improved betaadrenergic signaling after mechanical unloading
    • Hata JA, Williams ML, Schroder JN, Lima B, Keys JR, Blaxall BC, Petrofski JA, Jakoi A, Milano CA, Koch WJ. Lymphocyte levels of GRK2 (betaARK1) mirror changes in the LVAD-supported failing human heart: lower GRK2 associated with improved betaadrenergic signaling after mechanical unloading. J Card Fail 12: 360-368, 2006
    • (2006) J Card Fail , vol.12 , pp. 360-368
    • Hata, J.A.1    Williams, M.L.2    Schroder, J.N.3    Lima, B.4    Keys, J.R.5    Blaxall, B.C.6    Petrofski, J.A.7    Jakoi, A.8    Milano, C.A.9    Koch, W.J.10
  • 101
    • 0032513146 scopus 로고    scopus 로고
    • Novel subtype of G-protein-coupled receptor kinase, GRK7, in teleost cone photoreceptors
    • Hisatomi O, Matsuda S, Satoh T, Kotaka S, Imanishi Y, Tokunaga F. A novel subtype of G-protein-coupled receptor kinase, GRK7, in teleost cone photoreceptors. FEBS Lett 424: 159-164, 1998
    • (1998) FEBS Lett , vol.424 , pp. 159-164
    • Hisatomi, O.1    Matsuda, S.2    Satoh, T.3    Kotaka, S.4    Imanishi, Y.5    Tokunaga, F.A.6
  • 102
    • 0036733358 scopus 로고    scopus 로고
    • Cellular regulation of RGS proteins: Modulators and integrators of G protein signaling
    • Hollinger S, Hepler JR. Cellular regulation of RGS proteins: modulators and integrators of G protein signaling. Pharmacol Rev 54: 527-559, 2002
    • (2002) Pharmacol Rev , vol.54 , pp. 527-559
    • Hollinger, S.1    Hepler, J.R.2
  • 103
    • 79952796822 scopus 로고    scopus 로고
    • Activation of G proteincoupled receptor kinase 1 involves interactions between its N-terminal region and its kinase domain
    • Huang CC, Orban T, Jastrzebska B, Palczewski K, Tesmer JJ. Activation of G proteincoupled receptor kinase 1 involves interactions between its N-terminal region and its kinase domain. Biochemistry 50: 1940-1949, 2011
    • (2011) Biochemistry , vol.50 , pp. 1940-1949
    • Huang, C.C.1    Orban, T.2    Jastrzebska, B.3    Palczewski, K.4    Tesmer, J.J.5
  • 104
    • 79952784761 scopus 로고    scopus 로고
    • Recognition in the face of diversity: Interactions of heterotrimeric G proteins and G protein-coupled receptor (GPCR) kinases with activated GPCRs
    • Huang CC, Tesmer JJ. Recognition in the face of diversity: interactions of heterotrimeric G proteins and G protein-coupled receptor (GPCR) kinases with activated GPCRs. J Biol Chem 286: 7715-7721, 2011
    • (2011) J Biol Chem , vol.286 , pp. 7715-7721
    • Huang, C.C.1    Tesmer, J.J.2
  • 105
    • 66149178593 scopus 로고    scopus 로고
    • A surface of the kinase domain critical for the allosteric activation of G protein-coupled receptor kinases
    • Huang CC, Yoshino-Koh K, Tesmer JJ. A surface of the kinase domain critical for the allosteric activation of G protein-coupled receptor kinases. J Biol Chem 284: 17206-17215, 2009
    • (2009) J Biol Chem , vol.284 , pp. 17206-17215
    • Huang, C.C.1    Yoshino-Koh, K.2    Tesmer, J.J.3
  • 107
    • 79959540189 scopus 로고    scopus 로고
    • G protein-coupled receptor kinases in normal and failing myocardium
    • Huang ZM, Gold JI, Koch WJ. G protein-coupled receptor kinases in normal and failing myocardium. Front Biosci 16: 3047-3060, 2011
    • (2011) Front Biosci , vol.16 , pp. 3047-3060
    • Huang, Z.M.1    Gold, J.I.2    Koch, W.J.3
  • 109
    • 0034742442 scopus 로고    scopus 로고
    • Regulation of myocardial betaARK1 expression in catecholamine-induced cardiac hypertrophy in transgenic mice overexpressing alpha1B-adrenergic receptors
    • Iaccarino G, Keys JR, Rapacciuolo A, Shotwell KF, Lefkowitz RJ, Rockman HA, Koch WJ. Regulation of myocardial betaARK1 expression in catecholamine-induced cardiac hypertrophy in transgenic mice overexpressing alpha1B-adrenergic receptors. J Am Coll Cardiol 38: 534-540, 2001
    • (2001) J am Coll Cardiol , vol.38 , pp. 534-540
    • Iaccarino, G.1    Keys, J.R.2    Rapacciuolo, A.3    Shotwell, K.F.4    Lefkowitz, R.J.5    Rockman, H.A.6    Koch, W.J.7
  • 111
    • 0032573192 scopus 로고    scopus 로고
    • Reciprocal in vivo regulation of myocardial G protein-coupled receptor kinase expression by beta-adrenergic receptor stimulation and blockade
    • Iaccarino G, Tomhave ED, Lefkowitz RJ, Koch WJ. Reciprocal in vivo regulation of myocardial G protein-coupled receptor kinase expression by beta-adrenergic receptor stimulation and blockade. Circulation 98: 1783-1789, 1998
    • (1998) Circulation , vol.98 , pp. 1783-1789
    • Iaccarino, G.1    Tomhave, E.D.2    Lefkowitz, R.J.3    Koch, W.J.4
  • 112
    • 0027368165 scopus 로고
    • Structure and mechanism of the G protein-coupled receptor kinases
    • Inglese J, Freedman NJ, Koch WJ, Lefkowitz RJ. Structure and mechanism of the G protein-coupled receptor kinases. J Biol Chem 268: 23735-23738, 1993
    • (1993) J Biol Chem , vol.268 , pp. 23735-23738
    • Inglese, J.1    Freedman, N.J.2    Koch, W.J.3    Lefkowitz, R.J.4
  • 113
    • 0026726050 scopus 로고
    • Isoprenylation in regulation of signal transduction by G-protein-coupled receptor kinases
    • Inglese J, Koch WJ, Caron MG, Lefkowitz RJ. Isoprenylation in regulation of signal transduction by G-protein-coupled receptor kinases. Nature 359: 147-150, 1992
    • (1992) Nature , vol.359 , pp. 147-150
    • Inglese, J.1    Koch, W.J.2    Caron, M.G.3    Lefkowitz, R.J.4
  • 114
    • 84890397362 scopus 로고    scopus 로고
    • Regulation of nuclear factor kappaB (NF-kappaB) in the nucleus of cardiomyocytes by G protein-coupled receptor kinase 5 (GRK5)
    • Islam KN, Bae JW, Gao E, Koch WJ. Regulation of nuclear factor kappaB (NF-kappaB) in the nucleus of cardiomyocytes by G protein-coupled receptor kinase 5 (GRK5). J Biol Chem 288: 35683-35689, 2013
    • (2013) J Biol Chem , vol.288 , pp. 35683-35689
    • Islam, K.N.1    Bae, J.W.2    Gao, E.3    Koch, W.J.4
  • 115
    • 84859747948 scopus 로고    scopus 로고
    • Involvement of nuclear factor kappaB (NF-kappaB) signaling pathway in regulation of cardiac G protein-coupled receptor kinase 5 (GRK5) expression
    • Islam KN, Koch WJ. Involvement of nuclear factor kappaB (NF-kappaB) signaling pathway in regulation of cardiac G protein-coupled receptor kinase 5 (GRK5) expression. J Biol Chem 287: 12771-12778, 2012
    • (2012) J Biol Chem , vol.287 , pp. 12771-12778
    • Islam, K.N.1    Koch, W.J.2
  • 118
    • 34547781132 scopus 로고    scopus 로고
    • Plasma membrane and nuclear localization of G protein coupled receptor kinase 6A
    • Jiang X, Benovic JL, Wedegaertner PB. Plasma membrane and nuclear localization of G protein coupled receptor kinase 6A. Mol Biol Cell 18: 2960-2969, 2007
    • (2007) Mol Biol Cell , vol.18 , pp. 2960-2969
    • Jiang, X.1    Benovic, J.L.2    Wedegaertner, P.B.3
  • 119
    • 84877020037 scopus 로고    scopus 로고
    • Distinct structural features of G protein-coupled receptor kinase 5 (GRK5) regulate its nuclear localization and DNAbinding ability
    • Johnson LR, Robinson JD, Lester KN, Pitcher JA. Distinct structural features of G protein-coupled receptor kinase 5 (GRK5) regulate its nuclear localization and DNAbinding ability. PLoS One 8: e62508, 2013
    • (2013) Plos One , vol.8
    • Johnson, L.R.1    Robinson, J.D.2    Lester, K.N.3    Pitcher, J.A.4
  • 120
    • 8644290071 scopus 로고    scopus 로고
    • G protein-coupled receptor kinase 5 contains a DNA-binding nuclear localization sequence
    • Johnson LR, Scott MG, Pitcher JA. G protein-coupled receptor kinase 5 contains a DNA-binding nuclear localization sequence. Mol Cell Biol 24: 10169-10179, 2004
    • (2004) Mol Cell Biol , vol.24 , pp. 10169-10179
    • Johnson, L.R.1    Scott, M.G.2    Pitcher, J.A.3
  • 121
    • 34250351916 scopus 로고    scopus 로고
    • Phosphorylation of the endogenous thyrotropin-releasing hormone receptor in pituitary GH3 cells and pituitary tissue revealed by phosphosite-specific antibodies
    • Jones BW, Song GJ, Greuber EK, Hinkle PM. Phosphorylation of the endogenous thyrotropin-releasing hormone receptor in pituitary GH3 cells and pituitary tissue revealed by phosphosite-specific antibodies. J Biol Chem 282: 12893-12906, 2007
    • (2007) J Biol Chem , vol.282 , pp. 12893-12906
    • Jones, B.W.1    Song, G.J.2    Greuber, E.K.3    Hinkle, P.M.4
  • 123
    • 33751509646 scopus 로고    scopus 로고
    • A phosphorylation cluster of five serine and threonine residues in the C-terminus of the follicle-stimulating hormone receptor is important for desensitization but not for beta-arrestin-mediated ERK activation
    • Kara E, Crepieux P, Gauthier C, Martinat N, Piketty V, Guillou F, Reiter E. A phosphorylation cluster of five serine and threonine residues in the C-terminus of the follicle-stimulating hormone receptor is important for desensitization but not for beta-arrestin-mediated ERK activation. Mol Endocrinol 20: 3014-3026, 2006
    • (2006) Mol Endocrinol , vol.20 , pp. 3014-3026
    • Kara, E.1    Crepieux, P.2    Gauthier, C.3    Martinat, N.4    Piketty, V.5    Guillou, F.6    Reiter, E.7
  • 124
    • 0344585389 scopus 로고    scopus 로고
    • Increased acute inflammation, leukotriene B4-induced chemotaxis, and signaling in mice deficient for G protein-coupled receptor kinase 6
    • Kavelaars A, Vroon A, Raatgever RP, Fong AM, Premont RT, Patel DD, Lefkowitz RJ, Heijnen CJ. Increased acute inflammation, leukotriene B4-induced chemotaxis, and signaling in mice deficient for G protein-coupled receptor kinase 6. J Immunol 171: 6128-6134, 2003
    • (2003) J Immunol , vol.171 , pp. 6128-6134
    • Kavelaars, A.1    Vroon, A.2    Raatgever, R.P.3    Fong, A.M.4    Premont, R.T.5    Patel, D.D.6    Lefkowitz, R.J.7    Heijnen, C.J.8
  • 125
  • 126
    • 13444291851 scopus 로고    scopus 로고
    • Functional antagonism of different G protein-coupled receptor kinases for beta-arrestin-mediated angiotensin II receptor signaling
    • Kim J, Ahn S, Ren XR, Whalen EJ, Reiter E, Wei H, Lefkowitz RJ. Functional antagonism of different G protein-coupled receptor kinases for beta-arrestin-mediated angiotensin II receptor signaling. Proc Natl Acad Sci USA 102: 1442-1447, 2005
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 1442-1447
    • Kim, J.1    Ahn, S.2    Ren, X.R.3    Whalen, E.J.4    Reiter, E.5    Wei, H.6    Lefkowitz, R.J.7
  • 127
    • 84926645570 scopus 로고    scopus 로고
    • Springer-Verlag, March 21
    • Kobilka BK. G-protein coupled receptors Springer-Verlag. http://www.springerreference.com/index/chapterdbid/137855 (March 21, 2014).
    • (2014) G-Protein Coupled Receptors
    • Kobilka, B.K.1
  • 128
    • 0027481032 scopus 로고
    • The binding site for the beta gamma subunits of heterotrimeric G proteins on the beta-adrenergic receptor kinase
    • Koch WJ, Inglese J, Stone WC, Lefkowitz RJ. The binding site for the beta gamma subunits of heterotrimeric G proteins on the beta-adrenergic receptor kinase. J Biol Chem 268: 8256-8260, 1993
    • (1993) J Biol Chem , vol.268 , pp. 8256-8260
    • Koch, W.J.1    Inglese, J.2    Stone, W.C.3    Lefkowitz, R.J.4
  • 130
    • 0028338534 scopus 로고
    • GCRDb: A G-protein-coupled receptor database
    • Kolakowski LF Jr. GCRDb: a G-protein-coupled receptor database. Receptors Channels 2: 1-7, 1994
    • (1994) Receptors Channels , vol.2 , pp. 1-7
    • Kolakowski, L.F.1
  • 131
    • 0035910399 scopus 로고    scopus 로고
    • Phosphorylation of GRK2 by protein kinase C abolishes its inhibition by calmodulin
    • Krasel C, Dammeier S, Winstel R, Brockmann J, Mischak H, Lohse MJ. Phosphorylation of GRK2 by protein kinase C abolishes its inhibition by calmodulin. J Biol Chem 276: 1911-1915, 2001
    • (2001) J Biol Chem , vol.276 , pp. 1911-1915
    • Krasel, C.1    Dammeier, S.2    Winstel, R.3    Brockmann, J.4    Mischak, H.5    Lohse, M.J.6
  • 132
    • 0030793446 scopus 로고    scopus 로고
    • Mechanism of quenching of phototransduction. Binding competition between arrestin and transducin for phosphorhodopsin
    • Krupnick JG, Gurevich VV, Benovic JL. Mechanism of quenching of phototransduction. Binding competition between arrestin and transducin for phosphorhodopsin. J Biol Chem 272: 18125-18131, 1997
    • (1997) J Biol Chem , vol.272 , pp. 18125-18131
    • Krupnick, J.G.1    Gurevich, V.V.2    Benovic, J.L.3
  • 133
    • 0003091396 scopus 로고
    • Light dependent phosphorylation of rhodopsin by ATP
    • Kuhn H, Dreyer WJ. Light dependent phosphorylation of rhodopsin by ATP. FEBS Lett 20: 1-6, 1972
    • (1972) FEBS Lett , vol.20 , pp. 1-6
    • Kuhn, H.1    Dreyer, W.J.2
  • 134
    • 0027193453 scopus 로고
    • Cloning and expression of GRK5: A member of the G proteincoupled receptor kinase family
    • Kunapuli P, Benovic JL. Cloning and expression of GRK5: a member of the G proteincoupled receptor kinase family. Proc Natl Acad Sci USA 90: 5588-5592, 1993
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 5588-5592
    • Kunapuli, P.1    Benovic, J.L.2
  • 138
    • 0024794468 scopus 로고
    • Race, borderline hypertension, and hemodynamic responses to behavioral stress before and after beta-adrenergic blockade
    • Light KC, Sherwood A. Race, borderline hypertension, and hemodynamic responses to behavioral stress before and after beta-adrenergic blockade. Health Psychol 8: 577-595, 1989
    • (1989) Health Psychol , vol.8 , pp. 577-595
    • Light, K.C.1    Sherwood, A.2
  • 139
    • 84866447749 scopus 로고    scopus 로고
    • Pooled analyses of the associations of polymorphisms in the GRK4 and EMILIN1 genes with hypertension risk
    • Liu C, Xi B. Pooled analyses of the associations of polymorphisms in the GRK4 and EMILIN1 genes with hypertension risk. Int J Med Sci 9: 274-279, 2012
    • (2012) Int J Med Sci , vol.9 , pp. 274-279
    • Liu, C.1    Xi, B.2
  • 140
    • 84862776738 scopus 로고    scopus 로고
    • Biased signaling pathways in beta2-adrenergic receptor characterized by 19F-NMR
    • Liu JJ, Horst R, Katritch V, Stevens RC, Wuthrich K. Biased signaling pathways in beta2-adrenergic receptor characterized by 19F-NMR. Science 335: 1106-1110, 2012
    • (2012) Science , vol.335 , pp. 1106-1110
    • Liu, J.J.1    Horst, R.2    Katritch, V.3    Stevens, R.C.4    Wuthrich, K.5
  • 143
    • 0037799206 scopus 로고    scopus 로고
    • Keeping G proteins at bay: A complex between G protein-coupled receptor kinase 2 and Gbetagamma
    • Lodowski DT, Pitcher JA, Capel WD, Lefkowitz RJ, Tesmer JJ. Keeping G proteins at bay: a complex between G protein-coupled receptor kinase 2 and Gbetagamma. Science 300: 1256-1262, 2003
    • (2003) Science , vol.300 , pp. 1256-1262
    • Lodowski, D.T.1    Pitcher, J.A.2    Capel, W.D.3    Lefkowitz, R.J.4    Tesmer, J.J.5
  • 144
    • 33745207354 scopus 로고    scopus 로고
    • The structure ofGprotein-coupled receptor kinase (GRK)-6 defines a second lineage of GRKs
    • Lodowski DT, Tesmer VM, Benovic JL, Tesmer JJ. The structure ofGprotein-coupled receptor kinase (GRK)-6 defines a second lineage of GRKs. J Biol Chem 281: 16785-16793, 2006
    • (2006) J Biol Chem , vol.281 , pp. 16785-16793
    • Lodowski, D.T.1    Tesmer, V.M.2    Benovic, J.L.3    Tesmer, J.J.4
  • 146
    • 0025987010 scopus 로고
    • The receptor kinase family: Primary structure of rhodopsin kinase reveals similarities to the betaadrenergic receptor kinase
    • Lorenz W, Inglese J, Palczewski K, Onorato JJ, Caron MG, Lefkowitz RJ. The receptor kinase family: primary structure of rhodopsin kinase reveals similarities to the betaadrenergic receptor kinase. Proc Natl Acad Sci USA 88: 8715-8719, 1991
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 8715-8719
    • Lorenz, W.1    Inglese, J.2    Palczewski, K.3    Onorato, J.J.4    Caron, M.G.5    Lefkowitz, R.J.6
  • 147
    • 0030777365 scopus 로고    scopus 로고
    • Altered activity of palmitoylation-deficient and isoprenylated forms of the G protein-coupled receptor kinase GRK6
    • Loudon RP, Benovic JL. Altered activity of palmitoylation-deficient and isoprenylated forms of the G protein-coupled receptor kinase GRK6. J Biol Chem 272: 27422-27427, 1997
    • (1997) J Biol Chem , vol.272 , pp. 27422-27427
    • Loudon, R.P.1    Benovic, J.L.2
  • 148
    • 0345803950 scopus 로고    scopus 로고
    • Benovic JL.Gprotein-coupled receptor kinase interaction with Hsp90 mediates kinase maturation
    • Luo J, Benovic JL.Gprotein-coupled receptor kinase interaction with Hsp90 mediates kinase maturation. J Biol Chem 278: 50908-50914, 2003
    • (2003) J Biol Chem , vol.278 , pp. 50908-50914
    • Luo, J.1
  • 149
    • 33847728682 scopus 로고    scopus 로고
    • Adrenal GRK2 upregulation mediates sympathetic overdrive in heart failure
    • Lymperopoulos A, Rengo G, Funakoshi H, Eckhart AD, Koch WJ. Adrenal GRK2 upregulation mediates sympathetic overdrive in heart failure. Nat Med 13: 315-323, 2007
    • (2007) Nat Med , vol.13 , pp. 315-323
    • Lymperopoulos, A.1    Rengo, G.2    Funakoshi, H.3    Eckhart, A.D.4    Koch, W.J.5
  • 150
    • 77952368252 scopus 로고    scopus 로고
    • Reduction of sympathetic activity via adrenal-targeted GRK2 gene deletion attenuates heart failure progression and improves cardiac function after myocardial infarction
    • Lymperopoulos A, Rengo G, Gao E, Ebert SN, Dorn GW 2nd, Koch WJ. Reduction of sympathetic activity via adrenal-targeted GRK2 gene deletion attenuates heart failure progression and improves cardiac function after myocardial infarction. J Biol Chem 285: 16378-16386, 2010
    • (2010) J Biol Chem , vol.285 , pp. 16378-16386
    • Lymperopoulos, A.1    Rengo, G.2    Gao, E.3    Ebert, S.N.4    Dorn, G.W.5    Koch, W.J.6
  • 151
    • 84883565348 scopus 로고    scopus 로고
    • Adrenergic nervous system in heart failure: Pathophysiology and therapy
    • Lymperopoulos A, Rengo G, Koch WJ. Adrenergic nervous system in heart failure: pathophysiology and therapy. Circ Res 113: 739-753, 2013
    • (2013) Circ Res , vol.113 , pp. 739-753
    • Lymperopoulos, A.1    Rengo, G.2    Koch, W.J.3
  • 152
    • 38649085669 scopus 로고    scopus 로고
    • Modulation of adrenal catecholamine secretion by in vivo gene transfer and manipulation of G proteincoupled receptor kinase-2 activity
    • Lymperopoulos A, Rengo G, Zincarelli C, Soltys S, Koch WJ. Modulation of adrenal catecholamine secretion by in vivo gene transfer and manipulation of G proteincoupled receptor kinase-2 activity. Mol Ther 16: 302-307, 2008
    • (2008) Mol Ther , vol.16 , pp. 302-307
    • Lymperopoulos, A.1    Rengo, G.2    Zincarelli, C.3    Soltys, S.4    Koch, W.J.5
  • 153
    • 77951520888 scopus 로고    scopus 로고
    • G alpha(Q)-mediated activation of GRK2 by mechanical stretch in cardiac myocytes: The role of protein kinase C
    • Malhotra R, D’Souza KM, Staron ML, Birukov KG, Bodi I, Akhter SA. G alpha(q)-mediated activation of GRK2 by mechanical stretch in cardiac myocytes: the role of protein kinase C. J Biol Chem 285: 13748-13760, 2010
    • (2010) J Biol Chem , vol.285 , pp. 13748-13760
    • Malhotra, R.1    D’Souza, K.M.2    Staron, M.L.3    Birukov, K.G.4    Bodi, I.5    Akhter, S.A.6
  • 154
    • 84859000129 scopus 로고    scopus 로고
    • Paroxetine is associated with malformation during pregnancy
    • Mangin D, Healy D, Mintzes B. Paroxetine is associated with malformation during pregnancy. BMJ 343: d5060, 2011
    • (2011) BMJ , vol.343
    • Mangin, D.1    Healy, D.2    Mintzes, B.3
  • 155
    • 0035398487 scopus 로고    scopus 로고
    • G-protein-coupled receptors and signaling networks: Emerging paradigms
    • Marinissen MJ, Gutkind JS. G-protein-coupled receptors and signaling networks: emerging paradigms. Trends Pharmacol Sci 22: 368-376, 2001
    • (2001) Trends Pharmacol Sci , vol.22 , pp. 368-376
    • Marinissen, M.J.1    Gutkind, J.S.2
  • 161
    • 0033199408 scopus 로고    scopus 로고
    • Alternative splicing produces transcripts encoding four variants of mouse G-proteincoupled receptor kinase 6
    • Moepps B, Vatter P, Frodl R, Waechter F, Dixkens C, Hameister H, Gierschik P. Alternative splicing produces transcripts encoding four variants of mouse G-proteincoupled receptor kinase 6. Genomics 60: 199-209, 1999
    • (1999) Genomics , vol.60 , pp. 199-209
    • Moepps, B.1    Vatter, P.2    Frodl, R.3    Waechter, F.4    Dixkens, C.5    Hameister, H.6    Gierschik, P.7
  • 163
    • 33947314576 scopus 로고    scopus 로고
    • Regulation of receptor trafficking by GRKs and arrestins
    • Moore CA, Milano SK, Benovic JL. Regulation of receptor trafficking by GRKs and arrestins. Annu Rev Physiol 69: 451-482, 2007
    • (2007) Annu Rev Physiol , vol.69 , pp. 451-482
    • Moore, C.A.1    Milano, S.K.2    Benovic, J.L.3
  • 164
    • 0035375104 scopus 로고    scopus 로고
    • Agonist-dependent recruitment of phosphoinositide 3-kinase to the membrane by beta-adrenergic receptor kinase 1. A role in receptor sequestration
    • Naga Prasad SV, Barak LS, Rapacciuolo A, Caron MG, Rockman HA. Agonist-dependent recruitment of phosphoinositide 3-kinase to the membrane by beta-adrenergic receptor kinase 1. A role in receptor sequestration. J Biol Chem 276: 18953-18959, 2001
    • (2001) J Biol Chem , vol.276 , pp. 18953-18959
    • Naga Prasad, S.V.1    Barak, L.S.2    Rapacciuolo, A.3    Caron, M.G.4    Rockman, H.A.5
  • 169
    • 0028982276 scopus 로고
    • The beta-adrenergic receptor kinase (GRK2) is regulated by phospholipids
    • Onorato JJ, Gillis ME, Liu Y, Benovic JL, Ruoho AE. The beta-adrenergic receptor kinase (GRK2) is regulated by phospholipids. J Biol Chem 270: 21346-21353, 1995
    • (1995) J Biol Chem , vol.270 , pp. 21346-21353
    • Onorato, J.J.1    Gillis, M.E.2    Liu, Y.3    Benovic, J.L.4    Ruoho, A.E.5
  • 170
    • 84879411122 scopus 로고    scopus 로고
    • G-protein-coupled receptor kinase-5 mediates inflammation but does not regulate cellular infiltration or bacterial load in a polymicrobial sepsis model in mice
    • Packiriswamy N, Lee T, Raghavendra PB, Durairaj H, Wang H, Parameswaran N. G-protein-coupled receptor kinase-5 mediates inflammation but does not regulate cellular infiltration or bacterial load in a polymicrobial sepsis model in mice. J Innate Immun 5: 401-413, 2013
    • (2013) J Innate Immun , vol.5 , pp. 401-413
    • Packiriswamy, N.1    Lee, T.2    Raghavendra, P.B.3    Durairaj, H.4    Wang, H.5    Parameswaran, N.6
  • 173
    • 0027469860 scopus 로고
    • Identification of the N-terminal region in rhodopsin kinase involved in its interaction with rhodopsin
    • Palczewski K, Buczylko J, Lebioda L, Crabb JW, Polans AS. Identification of the N-terminal region in rhodopsin kinase involved in its interaction with rhodopsin. J Biol Chem 268: 6004-6013, 1993
    • (1993) J Biol Chem , vol.268 , pp. 6004-6013
    • Palczewski, K.1    Buczylko, J.2    Lebioda, L.3    Crabb, J.W.4    Polans, A.S.5
  • 174
    • 68049097974 scopus 로고    scopus 로고
    • Role of the amino terminus of G protein-coupled receptor kinase 2 in receptor phosphorylation
    • Pao CS, Barker BL, Benovic JL. Role of the amino terminus of G protein-coupled receptor kinase 2 in receptor phosphorylation. Biochemistry 48: 7325-7333, 2009
    • (2009) Biochemistry , vol.48 , pp. 7325-7333
    • Pao, C.S.1    Barker, B.L.2    Benovic, J.L.3
  • 175
    • 72449146904 scopus 로고    scopus 로고
    • G-protein-coupled-receptor kinases mediate TNFalpha-induced NFkappaB signalling via direct interaction with and phosphorylation of IkappaBalpha
    • Patial S, Luo J, Porter KJ, Benovic JL, Parameswaran N. G-protein-coupled-receptor kinases mediate TNFalpha-induced NFkappaB signalling via direct interaction with and phosphorylation of IkappaBalpha. Biochem J 425: 169-178, 2010
    • (2010) Biochem J , vol.425 , pp. 169-178
    • Patial, S.1    Luo, J.2    Porter, K.J.3    Benovic, J.L.4    Parameswaran, N.5
  • 176
    • 79251571503 scopus 로고    scopus 로고
    • G-protein coupled receptor kinase 5 mediates lipopolysaccharide-induced NFkappaB activation in primary macrophages and modulates inflammation in vivo in mice
    • Patial S, Shahi S, Saini Y, Lee T, Packiriswamy N, Appledorn DM, Lapres JJ, Amalfitano A, Parameswaran N. G-protein coupled receptor kinase 5 mediates lipopolysaccharide-induced NFkappaB activation in primary macrophages and modulates inflammation in vivo in mice. J Cell Physiol 226: 1323-1333, 2011
    • (2011) J Cell Physiol , vol.226 , pp. 1323-1333
    • Patial, S.1    Shahi, S.2    Saini, Y.3    Lee, T.4    Packiriswamy, N.5    Appledorn, D.M.6    Lapres, J.J.7    Amalfitano, A.8    Parameswaran, N.9
  • 177
    • 0035903669 scopus 로고    scopus 로고
    • Beta-arrestin-and c-Src-dependent degradation of G-protein-coupled receptor kinase 2
    • Penela P, Elorza A, Sarnago S, Mayor F Jr. Beta-arrestin-and c-Src-dependent degradation of G-protein-coupled receptor kinase 2. EMBO J 20: 5129-5138, 2001
    • (2001) EMBO J , vol.20 , pp. 5129-5138
    • Penela, P.1    Elorza, A.2    Sarnago, S.3    Mayor, F.4
  • 178
    • 29144497998 scopus 로고    scopus 로고
    • Mechanisms of regulation of G protein-coupled receptor kinases (GRKs) and cardiovascular disease
    • Penela P, Murga C, Ribas C, Tutor AS, Peregrin S, Mayor F Jr. Mechanisms of regulation of G protein-coupled receptor kinases (GRKs) and cardiovascular disease. Cardiovasc Res 69: 46-56, 2006
    • (2006) Cardiovasc Res , vol.69 , pp. 46-56
    • Penela, P.1    Murga, C.2    Ribas, C.3    Tutor, A.S.4    Peregrin, S.5    Mayor, F.6
  • 180
    • 0032567351 scopus 로고    scopus 로고
    • Degradation of the G proteincoupled receptor kinase 2 by the proteasome pathway
    • Penela P, Ruiz-Gomez A, Castano JG, Mayor F Jr. Degradation of the G proteincoupled receptor kinase 2 by the proteasome pathway. J Biol Chem 273: 35238-35244, 1998
    • (1998) J Biol Chem , vol.273 , pp. 35238-35244
    • Penela, P.1    Ruiz-Gomez, A.2    Castano, J.G.3    Mayor, F.4
  • 181
    • 0028243052 scopus 로고
    • Structure of the human gene encoding the beta-adrenergic receptor kinase
    • Penn RB, Benovic JL. Structure of the human gene encoding the beta-adrenergic receptor kinase. J Biol Chem 269: 14924-14930, 1994
    • (1994) J Biol Chem , vol.269 , pp. 14924-14930
    • Penn, R.B.1    Benovic, J.L.2
  • 182
    • 0030845179 scopus 로고    scopus 로고
    • G proteincoupled receptor kinase 3 (GRK3) gene disruption leads to loss of odorant receptor desensitization
    • Peppel K, Boekhoff I, McDonald P, Breer H, Caron MG, Lefkowitz RJ. G proteincoupled receptor kinase 3 (GRK3) gene disruption leads to loss of odorant receptor desensitization. J Biol Chem 272: 25425-25428, 1997
    • (1997) J Biol Chem , vol.272 , pp. 25425-25428
    • Peppel, K.1    Boekhoff, I.2    McDonald, P.3    Breer, H.4    Caron, M.G.5    Lefkowitz, R.J.6
  • 184
    • 0141457810 scopus 로고    scopus 로고
    • The beta-adrenergic receptor kinase in heart failure
    • Petrofski JA, Koch WJ. The beta-adrenergic receptor kinase in heart failure. J Mol Cell Cardiol 35: 1167-1174, 2003
    • (2003) J Mol Cell Cardiol , vol.35 , pp. 1167-1174
    • Petrofski, J.A.1    Koch, W.J.2
  • 185
    • 0029785214 scopus 로고    scopus 로고
    • Phosphatidylinositol 4,5-bisphosphate (PIP2)-enhanced G protein-coupled receptor kinase (GRK) activity. Location, structure, and regulation of the PIP2 binding site distinguishes the GRK subfamilies
    • Pitcher JA, Fredericks ZL, Stone WC, Premont RT, Stoffel RH, Koch WJ, Lefkowitz RJ. Phosphatidylinositol 4,5-bisphosphate (PIP2)-enhanced G protein-coupled receptor kinase (GRK) activity. Location, structure, and regulation of the PIP2 binding site distinguishes the GRK subfamilies. J Biol Chem 271: 24907-24913, 1996
    • (1996) J Biol Chem , vol.271 , pp. 24907-24913
    • Pitcher, J.A.1    Fredericks, Z.L.2    Stone, W.C.3    Premont, R.T.4    Stoffel, R.H.5    Koch, W.J.6    Lefkowitz, R.J.7
  • 188
    • 0033521109 scopus 로고    scopus 로고
    • Feedback inhibition of G protein-coupled receptor kinase 2 (GRK2) activity by extracellular signal-regulated kinases
    • Pitcher JA, Tesmer JJ, Freeman JL, Capel WD, Stone WC, Lefkowitz RJ. Feedback inhibition of G protein-coupled receptor kinase 2 (GRK2) activity by extracellular signal-regulated kinases. J Biol Chem 274: 34531-34534, 1999
    • (1999) J Biol Chem , vol.274 , pp. 34531-34534
    • Pitcher, J.A.1    Tesmer, J.J.2    Freeman, J.L.3    Capel, W.D.4    Stone, W.C.5    Lefkowitz, R.J.6
  • 189
    • 0029039613 scopus 로고
    • Pleckstrin homology domain-mediated membrane association and activation of the beta-adrenergic receptor kinase requires coordinate interaction with G beta gamma subunits and lipid
    • Pitcher JA, Touhara K, Payne ES, Lefkowitz RJ. Pleckstrin homology domain-mediated membrane association and activation of the beta-adrenergic receptor kinase requires coordinate interaction with G beta gamma subunits and lipid. J Biol Chem 270: 11707-11710, 1995
    • (1995) J Biol Chem , vol.270 , pp. 11707-11710
    • Pitcher, J.A.1    Touhara, K.2    Payne, E.S.3    Lefkowitz, R.J.4
  • 191
    • 0028920668 scopus 로고
    • Protein kinases that phosphorylate activated G protein-coupled receptors
    • Premont RT, Inglese J, Lefkowitz RJ. Protein kinases that phosphorylate activated G protein-coupled receptors. FASEB J 9: 175-182, 1995
    • (1995) FASEB J , vol.9 , pp. 175-182
    • Premont, R.T.1    Inglese, J.2    Lefkowitz, R.J.3
  • 192
    • 0028300574 scopus 로고
    • Identification, purification, and characterization of GRK5, a member of the family of G protein-coupled receptor kinases
    • Premont RT, Koch WJ, Inglese J, Lefkowitz RJ. Identification, purification, and characterization of GRK5, a member of the family of G protein-coupled receptor kinases. J Biol Chem 269: 6832-6841, 1994
    • (1994) J Biol Chem , vol.269 , pp. 6832-6841
    • Premont, R.T.1    Koch, W.J.2    Inglese, J.3    Lefkowitz, R.J.4
  • 193
    • 0032857194 scopus 로고    scopus 로고
    • The GRK4 subfamily of G protein-coupled receptor kinases. Alternative splicing, gene organization, and sequence conservation
    • Premont RT, Macrae AD, Aparicio SA, Kendall HE, Welch JE, Lefkowitz RJ. The GRK4 subfamily of G protein-coupled receptor kinases. Alternative splicing, gene organization, and sequence conservation. J Biol Chem 274: 29381-29389, 1999
    • (1999) J Biol Chem , vol.274 , pp. 29381-29389
    • Premont, R.T.1    Macrae, A.D.2    Aparicio, S.A.3    Kendall, H.E.4    Welch, J.E.5    Lefkowitz, R.J.6
  • 195
    • 0031022334 scopus 로고    scopus 로고
    • Regulation of the G protein-coupled receptor kinase GRK5 by protein kinase C
    • Pronin AN, Benovic JL. Regulation of the G protein-coupled receptor kinase GRK5 by protein kinase C. J Biol Chem 272: 3806-3812, 1997
    • (1997) J Biol Chem , vol.272 , pp. 3806-3812
    • Pronin, A.N.1    Benovic, J.L.2
  • 196
    • 0032553549 scopus 로고    scopus 로고
    • Structure-function analysis of G protein-coupled receptor kinase-5. Role of the carboxyl terminus in kinase regulation
    • Pronin AN, Carman CV, Benovic JL. Structure-function analysis of G protein-coupled receptor kinase-5. Role of the carboxyl terminus in kinase regulation. J Biol Chem 273: 31510-31518, 1998
    • (1998) J Biol Chem , vol.273 , pp. 31510-31518
    • Pronin, A.N.1    Carman, C.V.2    Benovic, J.L.3
  • 197
    • 0030800966 scopus 로고    scopus 로고
    • Regulation of G protein-coupled receptor kinases by calmodulin and localization of the calmodulin binding domain
    • Pronin AN, Satpaev DK, Slepak VZ, Benovic JL. Regulation of G protein-coupled receptor kinases by calmodulin and localization of the calmodulin binding domain. J Biol Chem 272: 18273-18280, 1997
    • (1997) J Biol Chem , vol.272 , pp. 18273-18280
    • Pronin, A.N.1    Satpaev, D.K.2    Slepak, V.Z.3    Benovic, J.L.4
  • 201
    • 77953819826 scopus 로고    scopus 로고
    • Beta-Arrestin-biased agonism of the angiotensin receptor induced by mechanical stress
    • Rakesh K, Yoo B, Kim IM, Salazar N, Kim KS, Rockman HA. beta-Arrestin-biased agonism of the angiotensin receptor induced by mechanical stress. Sci Signal 3: ra46, 2010
    • (2010) Sci Signal , vol.3
    • Rakesh, K.1    Yoo, B.2    Kim, I.M.3    Salazar, N.4    Kim, K.S.5    Rockman, H.A.6
  • 202
    • 0034595227 scopus 로고    scopus 로고
    • Analysis of the human G proteincoupled receptor kinase 2 (GRK2) gene promoter: Regulation by signal transduction systems in aortic smooth muscle cells
    • Ramos-Ruiz R, Penela P, Penn RB, Mayor F Jr. Analysis of the human G proteincoupled receptor kinase 2 (GRK2) gene promoter: regulation by signal transduction systems in aortic smooth muscle cells. Circulation 101: 2083-2089, 2000
    • (2000) Circulation , vol.101 , pp. 2083-2089
    • Ramos-Ruiz, R.1    Penela, P.2    Penn, R.B.3    Mayor, F.4
  • 203
    • 33644841768 scopus 로고    scopus 로고
    • The D1 dopamine receptor is constitutively phosphorylated by G protein-coupled receptor kinase 4
    • Rankin ML, Marinec PS, Cabrera DM, Wang Z, Jose PA, Sibley DR. The D1 dopamine receptor is constitutively phosphorylated by G protein-coupled receptor kinase 4. Mol Pharmacol 69: 759-769, 2006
    • (2006) Mol Pharmacol , vol.69 , pp. 759-769
    • Rankin, M.L.1    Marinec, P.S.2    Cabrera, D.M.3    Wang, Z.4    Jose, P.A.5    Sibley, D.R.6
  • 207
    • 13444270337 scopus 로고    scopus 로고
    • Different G protein-coupled receptor kinases govern G protein and beta-arrestin-mediated signaling of V2 vasopressin receptor
    • Ren XR, Reiter E, Ahn S, Kim J, Chen W, Lefkowitz RJ. Different G protein-coupled receptor kinases govern G protein and beta-arrestin-mediated signaling of V2 vasopressin receptor. Proc Natl Acad Sci USA 102: 1448-1453, 2005
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 1448-1453
    • Ren, X.R.1    Reiter, E.2    Ahn, S.3    Kim, J.4    Chen, W.5    Lefkowitz, R.J.6
  • 208
    • 59049097977 scopus 로고    scopus 로고
    • Myocardial adeno-associated virus serotype 6-betaARKct gene therapy improves cardiac function and normalizes the neurohormonal axis in chronic heart failure
    • Rengo G, Lymperopoulos A, Zincarelli C, Donniacuo M, Soltys S, Rabinowitz JE, Koch WJ. Myocardial adeno-associated virus serotype 6-betaARKct gene therapy improves cardiac function and normalizes the neurohormonal axis in chronic heart failure. Circulation 119: 89-98, 2009
    • (2009) Circulation , vol.119 , pp. 89-98
    • Rengo, G.1    Lymperopoulos, A.2    Zincarelli, C.3    Donniacuo, M.4    Soltys, S.5    Rabinowitz, J.E.6    Koch, W.J.7
  • 209
    • 0027490599 scopus 로고
    • Phosphorylation and desensitization of human m2 muscarinic cholinergic receptors by two isoforms of the beta-adrenergic receptor kinase
    • Richardson RM, Kim C, Benovic JL, Hosey MM. Phosphorylation and desensitization of human m2 muscarinic cholinergic receptors by two isoforms of the beta-adrenergic receptor kinase. J Biol Chem 268: 13650-13656, 1993
    • (1993) J Biol Chem , vol.268 , pp. 13650-13656
    • Richardson, R.M.1    Kim, C.2    Benovic, J.L.3    Hosey, M.M.4
  • 211
    • 0032540893 scopus 로고    scopus 로고
    • Control of myocardial contractile function by the level of beta-adrenergic receptor kinase 1 in gene-targeted mice
    • Rockman HA, Choi DJ, Akhter SA, Jaber M, Giros B, Lefkowitz RJ, Caron MG, Koch WJ. Control of myocardial contractile function by the level of beta-adrenergic receptor kinase 1 in gene-targeted mice. J Biol Chem 273: 18180-18184, 1998
    • (1998) J Biol Chem , vol.273 , pp. 18180-18184
    • Rockman, H.A.1    Choi, D.J.2    Akhter, S.A.3    Jaber, M.4    Giros, B.5    Lefkowitz, R.J.6    Caron, M.G.7    Koch, W.J.8
  • 213
    • 0037050009 scopus 로고    scopus 로고
    • Seven-transmembrane-spanning receptors and heart function
    • Rockman HA, Koch WJ, Lefkowitz RJ. Seven-transmembrane-spanning receptors and heart function. Nature 415: 206-212, 2002
    • (2002) Nature , vol.415 , pp. 206-212
    • Rockman, H.A.1    Koch, W.J.2    Lefkowitz, R.J.3
  • 216
    • 0028357074 scopus 로고
    • Two isoforms of G protein-coupled receptor kinase 4 identified by molecular cloning
    • Sallese M, Lombardi MS, De Blasi A. Two isoforms of G protein-coupled receptor kinase 4 identified by molecular cloning. Biochem Biophys Res Commun 199: 848-854, 1994
    • (1994) Biochem Biophys Res Commun , vol.199 , pp. 848-854
    • Sallese, M.1    Lombardi, M.S.2    De Blasi, A.3
  • 219
    • 0036265366 scopus 로고    scopus 로고
    • Visualizing preference of G protein-coupled receptor kinase 3 for the process of kappa-opioid receptor sequestration
    • Schulz R, Wehmeyer A, Schulz K. Visualizing preference of G protein-coupled receptor kinase 3 for the process of kappa-opioid receptor sequestration. Mol Pharmacol 61: 1444-1452, 2002
    • (2002) Mol Pharmacol , vol.61 , pp. 1444-1452
    • Schulz, R.1    Wehmeyer, A.2    Schulz, K.3
  • 220
    • 0034333501 scopus 로고    scopus 로고
    • Expression of the G protein-coupled receptor kinase 2 during early mouse embryogenesis
    • Sefton M, Blanco MJ, Penela P, Mayor F, Nieto MA. Expression of the G protein-coupled receptor kinase 2 during early mouse embryogenesis. Mech Dev 98: 127-131, 2000
    • (2000) Mech Dev , vol.98 , pp. 127-131
    • Sefton, M.1    Blanco, M.J.2    Penela, P.3    Mayor, F.4    Nieto, M.A.5
  • 221
    • 0035814968 scopus 로고    scopus 로고
    • In vivo ventricular gene delivery of a beta-adrenergic receptor kinase inhibitor to the failing heart reverses cardiac dysfunction
    • Shah AS, White DC, Emani S, Kypson AP, Lilly RE, Wilson K, Glower DD, Lefkowitz RJ, Koch WJ. In vivo ventricular gene delivery of a beta-adrenergic receptor kinase inhibitor to the failing heart reverses cardiac dysfunction. Circulation 103: 1311-1316, 2001
    • (2001) Circulation , vol.103 , pp. 1311-1316
    • Shah, A.S.1    White, D.C.2    Emani, S.3    Kypson, A.P.4    Lilly, R.E.5    Wilson, K.6    Glower, D.D.7    Lefkowitz, R.J.8    Koch, W.J.9
  • 223
    • 0027292624 scopus 로고
    • Responsiveness to alpha-and beta-adrenergic receptor agonists. Effects of race in borderline hypertensive compared to normotensive men
    • Sherwood A, Hinderliter AL. Responsiveness to alpha-and beta-adrenergic receptor agonists. Effects of race in borderline hypertensive compared to normotensive men. Am J Hypertens 6: 630-635, 1993
    • (1993) Am J Hypertens , vol.6 , pp. 630-635
    • Sherwood, A.1    Hinderliter, A.L.2
  • 224
    • 0018119642 scopus 로고
    • Light-dependent phosphorylation of rhodopsin. Purification and properties of rhodopsin kinase
    • Shichi H, Somers RL. Light-dependent phosphorylation of rhodopsin. Purification and properties of rhodopsin kinase. J Biol Chem 253: 7040-7046, 1978
    • (1978) J Biol Chem , vol.253 , pp. 7040-7046
    • Shichi, H.1
  • 226
    • 0034255123 scopus 로고    scopus 로고
    • Speeding molecular recognition by using the folding funnel: The fly-casting mechanism
    • Shoemaker BA, Portman JJ, Wolynes PG. Speeding molecular recognition by using the folding funnel: the fly-casting mechanism. Proc Natl Acad Sci USA 97: 8868-8873, 2000
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 8868-8873
    • Shoemaker, B.A.1    Portman, J.J.2    Wolynes, P.G.3
  • 229
    • 0021925095 scopus 로고
    • Homologous desensitization of adenylate cyclase is associated with phosphorylation of the beta-adrenergic receptor
    • Sibley DR, Strasser RH, Caron MG, Lefkowitz RJ. Homologous desensitization of adenylate cyclase is associated with phosphorylation of the beta-adrenergic receptor. J Biol Chem 260: 3883-3886, 1985
    • (1985) J Biol Chem , vol.260 , pp. 3883-3886
    • Sibley, D.R.1    Strasser, R.H.2    Caron, M.G.3    Lefkowitz, R.J.4
  • 230
    • 0028906896 scopus 로고
    • Neurohormonal activation in patients with acute myocardial infarction or chronic congestive heart failure. With special reference to treatment with angiotensin converting enzyme inhibitors
    • Sigurdsson A. Neurohormonal activation in patients with acute myocardial infarction or chronic congestive heart failure. With special reference to treatment with angiotensin converting enzyme inhibitors. Blood Press Suppl 1: 1-45, 1995
    • (1995) Blood Press , pp. 1-45
    • Sigurdsson, A.1
  • 231
    • 0021212720 scopus 로고
    • Rhodopsin kinase activity in the mammalian pineal gland and other tissues
    • Somers RL, Klein DC. Rhodopsin kinase activity in the mammalian pineal gland and other tissues. Science 226: 182-184, 1984
    • (1984) Science , vol.226 , pp. 182-184
    • Somers, R.L.1    Klein, D.C.2
  • 233
    • 77957229688 scopus 로고    scopus 로고
    • Intracardiac injection of AdGRK5-NT reduces left ventricular hypertrophy by inhibiting NF-kappaB-dependent hypertrophic gene expression
    • Sorriento D, Santulli G, Fusco A, Anastasio A, Trimarco B, Iaccarino G. Intracardiac injection of AdGRK5-NT reduces left ventricular hypertrophy by inhibiting NF-kappaB-dependent hypertrophic gene expression. Hypertension 56: 696-704, 2010
    • (2010) Hypertension , vol.56 , pp. 696-704
    • Sorriento, D.1    Santulli, G.2    Fusco, A.3    Anastasio, A.4    Trimarco, B.5    Iaccarino, G.6
  • 234
    • 2542465907 scopus 로고    scopus 로고
    • Association of G-protein-coupled receptor kinase 4 haplotypes, but not HSD3B1 or PTP1B polymorphisms, with essential hypertension
    • Speirs HJ, Katyk K, Kumar NN, Benjafield AV, Wang WY, Morris BJ. Association of G-protein-coupled receptor kinase 4 haplotypes, but not HSD3B1 or PTP1B polymorphisms, with essential hypertension. J Hypertens 22: 931-936, 2004
    • (2004) J Hypertens , vol.22 , pp. 931-936
    • Speirs, H.J.1    Katyk, K.2    Kumar, N.N.3    Benjafield, A.V.4    Wang, W.Y.5    Morris, B.J.6
  • 235
    • 72649085372 scopus 로고    scopus 로고
    • L41Q polymorphism of the G protein coupled receptor kinase 5 is associated with left ventricular apical ballooning syndrome
    • Spinelli L, Trimarco V, Di Marino S, Marino M, Iaccarino G, Trimarco B. L41Q polymorphism of the G protein coupled receptor kinase 5 is associated with left ventricular apical ballooning syndrome. Eur J Heart Fail 12: 13-16, 2010
    • (2010) Eur J Heart Fail , vol.12 , pp. 13-16
    • Spinelli, L.1    Trimarco, V.2    Di Marino, S.3    Marino, M.4    Iaccarino, G.5    Trimarco, B.6
  • 237
    • 0029186559 scopus 로고
    • Regulation of G protein-coupled receptors by receptor kinases and arrestins
    • Sterne-Marr R, Benovic JL. Regulation of G protein-coupled receptors by receptor kinases and arrestins. Vitam Horm 51: 193-234, 1995
    • (1995) Vitam Horm , vol.51 , pp. 193-234
    • Sterne-Marr, R.1    Benovic, J.L.2
  • 239
    • 84893542709 scopus 로고    scopus 로고
    • G protein-coupled receptor kinase 2 moderates recruitment of THP-1 cells to the endothelium by limiting histamine-invoked Weibel-Palade body exocytosis
    • Stevenson NL, Martin-Martin B, Freeman J, Kriston-Vizi J, Ketteler R, Cutler DF. G protein-coupled receptor kinase 2 moderates recruitment of THP-1 cells to the endothelium by limiting histamine-invoked Weibel-Palade body exocytosis. J Thromb Haemost 12: 261-272, 2014
    • (2014) J Thromb Haemost , vol.12 , pp. 261-272
    • Stevenson, N.L.1    Martin-Martin, B.2    Freeman, J.3    Kriston-Vizi, J.4    Ketteler, R.5    Cutler, D.F.6
  • 240
    • 0032541974 scopus 로고    scopus 로고
    • Palmitoylation increases the kinase activity of the G protein-coupled receptor kinase, GRK6
    • Stoffel RH, Inglese J, Macrae AD, Lefkowitz RJ, Premont RT. Palmitoylation increases the kinase activity of the G protein-coupled receptor kinase, GRK6. Biochemistry 37: 16053-16059, 1998
    • (1998) Biochemistry , vol.37 , pp. 16053-16059
    • Stoffel, R.H.1    Inglese, J.2    Macrae, A.D.3    Lefkowitz, R.J.4    Premont, R.T.5
  • 241
    • 0028030060 scopus 로고
    • Palmitoylation of G protein-coupled receptor kinase, GRK6. Lipid modification diversity in the GRK family
    • Stoffel RH, Randall RR, Premont RT, Lefkowitz RJ, Inglese J. Palmitoylation of G protein-coupled receptor kinase, GRK6. Lipid modification diversity in the GRK family. J Biol Chem 269: 27791-27794, 1994
    • (1994) J Biol Chem , vol.269 , pp. 27791-27794
    • Stoffel, R.H.1    Randall, R.R.2    Premont, R.T.3    Lefkowitz, R.J.4    Inglese, J.5
  • 242
    • 0022973987 scopus 로고
    • Beta-agonist-and prostaglandin E1-induced translocation of the beta-adrenergic receptor kinase: Evidence that the kinase may act on multiple adenylate cyclase-coupled receptors
    • Strasser RH, Benovic JL, Caron MG, Lefkowitz RJ. Beta-agonist-and prostaglandin E1-induced translocation of the beta-adrenergic receptor kinase: evidence that the kinase may act on multiple adenylate cyclase-coupled receptors. Proc Natl Acad Sci USA 83: 6362-6366, 1986
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 6362-6366
    • Strasser, R.H.1    Benovic, J.L.2    Caron, M.G.3    Lefkowitz, R.J.4
  • 243
    • 0022552720 scopus 로고
    • A novel catecholamine-activated adenosine cyclic 3=,5=-phosphate independent pathway for beta-adrenergic receptor phosphorylation in wild-type and mutant S49 lymphoma cells: Mechanism of homologous desensitization of adenylate cyclase
    • Strasser RH, Sibley DR, Lefkowitz RJ. A novel catecholamine-activated adenosine cyclic 3=,5=-phosphate independent pathway for beta-adrenergic receptor phosphorylation in wild-type and mutant S49 lymphoma cells: mechanism of homologous desensitization of adenylate cyclase. Biochemistry 25: 1371-1377, 1986
    • (1986) Biochemistry , vol.25 , pp. 1371-1377
    • Strasser, R.H.1    Sibley, D.R.2    Lefkowitz, R.J.3
  • 244
    • 80055006025 scopus 로고    scopus 로고
    • Causes endothelial dysfunction via the GRK2/Akt/eNOS pathway in aortas from a murine type 2 diabetic model
    • Taguchi K, Kobayashi T, Takenouchi Y, Matsumoto T, Kamata K. Angiotensin II causes endothelial dysfunction via the GRK2/Akt/eNOS pathway in aortas from a murine type 2 diabetic model. Pharmacol Res 64: 535-546, 2011
    • (2011) Pharmacol Res , vol.64 , pp. 535-546
    • Taguchi, K.1    Kobayashi, T.2    Takenouchi, Y.3    Matsumoto, T.4    Kamata, K.5    Angiotensin, I.I.6
  • 245
    • 84898781405 scopus 로고    scopus 로고
    • Protein-coupled receptor kinase 2 of Akt/endothelial nitric-oxide synthase signaling in human vascular endothelial cells under conditions of hyperglycemia with high insulin levels
    • Taguchi K, Sakata K, Ohashi W, Imaizumi T, Imura J, Hattori Y. Tonic inhibition by G protein-coupled receptor kinase 2 of Akt/endothelial nitric-oxide synthase signaling in human vascular endothelial cells under conditions of hyperglycemia with high insulin levels. J Pharmacol Exp Ther 349: 199-208, 2014
    • (2014) J Pharmacol Exp Ther , vol.349 , pp. 199-208
    • Taguchi, K.1    Sakata, K.2    Ohashi, W.3    Imaizumi, T.4    Imura, J.5    Hattori, Y.6    Tonic Inhibition By, G.7
  • 246
    • 79952792916 scopus 로고    scopus 로고
    • Differential effects of inescapable stress on locus coeruleus GRK3, alpha2-adrenoceptor and CRF1 receptor levels in learned helpless and non-helpless rats: A potential link to stress resilience
    • Taneja M, Salim S, Saha K, Happe HK, Qutna N, Petty F, Bylund DB, Eikenburg DC. Differential effects of inescapable stress on locus coeruleus GRK3, alpha2-adrenoceptor and CRF1 receptor levels in learned helpless and non-helpless rats: a potential link to stress resilience. Behav Brain Res 221: 25-33, 2011
    • (2011) Behav Brain Res , vol.221 , pp. 25-33
    • Taneja, M.1    Salim, S.2    Saha, K.3    Happe, H.K.4    Qutna, N.5    Petty, F.6    Bylund, D.B.7    Eikenburg, D.C.8
  • 248
    • 0035940386 scopus 로고    scopus 로고
    • Ventricular dysfunction after cardioplegic arrest is improved after myocardial gene transfer of a beta-adrenergic receptor kinase inhibitor
    • Tevaearai HT, Eckhart AD, Shotwell KF, Wilson K, Koch WJ. Ventricular dysfunction after cardioplegic arrest is improved after myocardial gene transfer of a beta-adrenergic receptor kinase inhibitor. Circulation 104: 2069-2074, 2001
    • (2001) Circulation , vol.104 , pp. 2069-2074
    • Tevaearai, H.T.1    Eckhart, A.D.2    Shotwell, K.F.3    Wilson, K.4    Koch, W.J.5
  • 250
    • 0346034895 scopus 로고    scopus 로고
    • Differential G protein receptor kinase 2 expression in compensated hypertrophy and heart failure after myocardial infarction in the rat
    • Theilade J, Strom C, Christiansen T, Haunso S, Sheikh SP. Differential G protein receptor kinase 2 expression in compensated hypertrophy and heart failure after myocardial infarction in the rat. Basic Res Cardiol 98: 97-103, 2003
    • (2003) Basic Res Cardiol , vol.98 , pp. 97-103
    • Theilade, J.1    Strom, C.2    Christiansen, T.3    Haunso, S.4    Sheikh, S.P.5
  • 252
    • 67749139960 scopus 로고    scopus 로고
    • Rockman HA. Beta-Arrestin mediates beta1-adrenergic receptor-epidermal growth factor receptor interaction and downstream signaling
    • Tilley DG, Kim IM, Patel PA, Violin JD, Rockman HA. beta-Arrestin mediates beta1-adrenergic receptor-epidermal growth factor receptor interaction and downstream signaling. J Biol Chem 284: 20375-20386, 2009
    • (2009) J Biol Chem , vol.284 , pp. 20375-20386
    • Tilley, D.G.1    Kim, I.M.2    Patel, P.A.3    Violin, J.D.4
  • 253
    • 0027497584 scopus 로고
    • Altered expression of betaadrenergic receptor kinase and beta 1-adrenergic receptors in the failing human heart
    • Ungerer M, Bohm M, Elce JS, Erdmann E, Lohse MJ. Altered expression of betaadrenergic receptor kinase and beta 1-adrenergic receptors in the failing human heart. Circulation 87: 454-463, 1993
    • (1993) Circulation , vol.87 , pp. 454-463
    • Ungerer, M.1    Bohm, M.2    Elce, J.S.3    Erdmann, E.4    Lohse, M.J.5
  • 254
    • 3543038233 scopus 로고    scopus 로고
    • GRK2 is an endogenous protein inhibitor of the insulin signaling pathway for glucose transport stimulation
    • Usui I, Imamura T, Satoh H, Huang J, Babendure JL, Hupfeld CJ, Olefsky JM. GRK2 is an endogenous protein inhibitor of the insulin signaling pathway for glucose transport stimulation. EMBO J 23: 2821-2829, 2004
    • (2004) EMBO J , vol.23 , pp. 2821-2829
    • Usui, I.1    Imamura, T.2    Satoh, H.3    Huang, J.4    Babendure, J.L.5    Hupfeld, C.J.6    Olefsky, J.M.7
  • 257
    • 28344450854 scopus 로고    scopus 로고
    • The variable C-terminal extension of G-protein-coupled receptor kinase 6 constitutes an accessorial autoregulatory domain
    • Vatter P, Stoesser C, Samel I, Gierschik P, Moepps B. The variable C-terminal extension of G-protein-coupled receptor kinase 6 constitutes an accessorial autoregulatory domain. FEBS J 272: 6039-6051, 2005
    • (2005) FEBS J , vol.272 , pp. 6039-6051
    • Vatter, P.1    Stoesser, C.2    Samel, I.3    Gierschik, P.4    Moepps, B.5
  • 259
    • 0035653752 scopus 로고    scopus 로고
    • Myocardial distribution and regulation of GRK and beta-arrestin isoforms in congestive heart failure in rats
    • Vinge LE, Oie E, Andersson Y, Grogaard HK, Andersen G, Attramadal H. Myocardial distribution and regulation of GRK and beta-arrestin isoforms in congestive heart failure in rats. Am J Physiol Heart Circ Physiol 281: H2490-H2499, 2001
    • (2001) Am J Physiol Heart Circ Physiol , vol.281 , pp. H2490-H2499
    • Vinge, L.E.1    Oie, E.2    Ersson, Y.3    Grogaard, H.K.4    Ersen, G.5    Attramadal, H.6
  • 260
    • 48249116367 scopus 로고    scopus 로고
    • Gene therapy in heart failure
    • Vinge LE, Raake PW, Koch WJ. Gene therapy in heart failure. Circ Res 102: 1458-1470, 2008
    • (2008) Circ Res , vol.102 , pp. 1458-1470
    • Vinge, L.E.1    Raake, P.W.2    Koch, W.J.3
  • 262
    • 4043174174 scopus 로고    scopus 로고
    • Increased expression of G-proteincoupled receptor kinases 3 and 4 in hyperfunctioning thyroid nodules
    • Voigt C, Holzapfel HP, Meyer S, Paschke R. Increased expression of G-proteincoupled receptor kinases 3 and 4 in hyperfunctioning thyroid nodules. J Endocrinol 182: 173-182, 2004
    • (2004) J Endocrinol , vol.182 , pp. 173-182
    • Voigt, C.1    Holzapfel, H.P.2    Meyer, S.3    Paschke, R.4
  • 266
    • 55749111239 scopus 로고    scopus 로고
    • A polymorphism of G-protein coupled receptor kinase5 alters agonist-promoted desensitization of beta2-adrenergic receptors
    • Wang WC, Mihlbachler KA, Bleecker ER, Weiss ST, Liggett SB. A polymorphism of G-protein coupled receptor kinase5 alters agonist-promoted desensitization of beta2-adrenergic receptors. Pharmacogenet Genomics 18: 729-732, 2008
    • (2008) Pharmacogenet Genomics , vol.18 , pp. 729-732
    • Wang, W.C.1    Mihlbachler, K.A.2    Bleecker, E.R.3    Weiss, S.T.4    Liggett, S.B.5
  • 267
    • 33749565407 scopus 로고    scopus 로고
    • Association study of G protein-coupled receptor kinase 4 gene variants with essential hypertension in northern Han Chinese
    • Wang Y, Li B, Zhao W, Liu P, Zhao Q, Chen S, Li H, Gu D. Association study of G protein-coupled receptor kinase 4 gene variants with essential hypertension in northern Han Chinese. Ann Hum Genet 70: 778-783, 2006
    • (2006) Ann Hum Genet , vol.70 , pp. 778-783
    • Wang, Y.1    Li, B.2    Zhao, W.3    Liu, P.4    Zhao, Q.5    Chen, S.6    Li, H.7    Gu, D.8
  • 270
    • 0016435356 scopus 로고
    • Light-stimulated phosphorylation of rhodopsin in the retina: The presence of a protein kinase that is specific for photobleached rhodopsin
    • Weller M, Virmaux N, Mandel P. Light-stimulated phosphorylation of rhodopsin in the retina: the presence of a protein kinase that is specific for photobleached rhodopsin. Proc Natl Acad Sci USA 72: 381-385, 1975
    • (1975) Proc Natl Acad Sci USA , vol.72 , pp. 381-385
    • Weller, M.1    Virmaux, N.2    Mandel, P.3
  • 273
    • 0034625008 scopus 로고    scopus 로고
    • Preservation of myocardial beta-adrenergic receptor signaling delays the development of heart failure after myocardial infarction
    • White DC, Hata JA, Shah AS, Glower DD, Lefkowitz RJ, Koch WJ. Preservation of myocardial beta-adrenergic receptor signaling delays the development of heart failure after myocardial infarction. Proc Natl Acad Sci USA 97: 5428-5433, 2000
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 5428-5433
    • White, D.C.1    Hata, J.A.2    Shah, A.S.3    Glower, D.D.4    Lefkowitz, R.J.5    Koch, W.J.6
  • 274
    • 0028921426 scopus 로고
    • Duration and amplitude of the light-induced cGMP hydrolysis in vertebrate photoreceptors are regulated by multiple phosphorylation of rhodopsin and by arrestin binding
    • Wilden U. Duration and amplitude of the light-induced cGMP hydrolysis in vertebrate photoreceptors are regulated by multiple phosphorylation of rhodopsin and by arrestin binding. Biochemistry 34: 1446-1454, 1995
    • (1995) Biochemistry , vol.34 , pp. 1446-1454
    • Wilden, U.1
  • 276
    • 0029877815 scopus 로고    scopus 로고
    • Protein kinase cross-talk: Membrane targeting of the beta-adrenergic receptor kinase by protein kinase C
    • Winstel R, Freund S, Krasel C, Hoppe E, Lohse MJ. Protein kinase cross-talk: membrane targeting of the beta-adrenergic receptor kinase by protein kinase C. Proc Natl Acad Sci USA 93: 2105-2109, 1996
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 2105-2109
    • Winstel, R.1    Freund, S.2    Krasel, C.3    Hoppe, E.4    Lohse, M.J.5
  • 278
    • 84896970319 scopus 로고    scopus 로고
    • GRK5 intronic (CA)n polymorphisms associated with type 2 diabetes in Chinese Hainan Island
    • Xia Z, Yang T, Wang Z, Dong J, Liang C. GRK5 intronic (CA)n polymorphisms associated with type 2 diabetes in Chinese Hainan Island. PLoS One 9: e90597, 2014
    • (2014) Plos One , vol.9
    • Xia, Z.1    Yang, T.2    Wang, Z.3    Dong, J.4    Liang, C.5
  • 279
    • 84885575620 scopus 로고    scopus 로고
    • Improvement of vascular insulin sensitivity by downregulation of GRK2 mediates exercise-induced alleviation of hypertension in spontaneously hypertensive rats
    • Xing W, Li Y, Zhang H, Mi C, Hou Z, Quon MJ, Gao F. Improvement of vascular insulin sensitivity by downregulation of GRK2 mediates exercise-induced alleviation of hypertension in spontaneously hypertensive rats. Am J Physiol Heart Circ Physiol 305: H1111-H1119, 2013
    • (2013) Am J Physiol Heart Circ Physiol , vol.305 , pp. H1111-H1119
    • Xing, W.1    Li, Y.2    Zhang, H.3    Mi, C.4    Hou, Z.5    Quon, M.J.6    Gao, F.7
  • 280
    • 0028332848 scopus 로고
    • Transduction mechanisms of vertebrate and invertebrate photoreceptors
    • Yarfitz S, Hurley JB. Transduction mechanisms of vertebrate and invertebrate photoreceptors. J Biol Chem 269: 14329-14332, 1994
    • (1994) J Biol Chem , vol.269 , pp. 14329-14332
    • Yarfitz, S.1    Hurley, J.B.2
  • 282
    • 84863012898 scopus 로고    scopus 로고
    • Nuclear effects of G-protein receptor kinase 5 on histone deacetylase 5-regulated gene transcription in heart failure
    • Zhang Y, Matkovich SJ, Duan X, Gold JI, Koch WJ, Dorn GW 2nd. Nuclear effects of G-protein receptor kinase 5 on histone deacetylase 5-regulated gene transcription in heart failure. Circ Heart Fail 4: 659-668, 2011
    • (2011) Circ Heart Fail , vol.4 , pp. 659-668
    • Zhang, Y.1    Matkovich, S.J.2    Duan, X.3    Gold, J.I.4    Koch, W.J.5    Dorn, G.W.6
  • 285
    • 67649856866 scopus 로고    scopus 로고
    • Selective engagement of G protein coupled receptor kinases (GRKs) encodes distinct functions of biased ligands
    • Zidar DA, Violin JD, Whalen EJ, Lefkowitz RJ. Selective engagement of G protein coupled receptor kinases (GRKs) encodes distinct functions of biased ligands. Proc Natl Acad Sci USA 106: 9649-9654, 2009.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 9649-9654
    • Zidar, D.A.1    Violin, J.D.2    Whalen, E.J.3    Lefkowitz, R.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.