Molecular basis for activation of G protein-coupled receptor kinases

EMBO Journal

Volumn 29, Issue 19, 2010, Pages 3249-3259

  Boguth, Cassandra A ^a   Singh, Puja ^a,c   Huang, Chih Chin ^a   Tesmer, John J G ^a,b  

^a UNIVERSITY OF MICHIGAN   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c NONE   (United States)

Author keywords

crystallography; G protein coupled receptors; protein kinases; regulation; signal transduction

Indexed keywords

G PROTEIN COUPLED RECEPTOR KINASE 6; PHOSPHOLIPID; G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR KINASE; G-PROTEIN-COUPLED RECEPTOR KINASE 6; PYRIMIDINE NUCLEOSIDE; SANGIVAMYCIN;

ALPHA HELIX; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME CONFORMATION; ENZYME PHOSPHORYLATION; ENZYME STRUCTURE; GENE MUTATION; HYDROPHOBICITY; MOLECULAR DOCKING; MUTATIONAL ANALYSIS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN LIPID INTERACTION; AMINO ACID SEQUENCE; CHEMICAL STRUCTURE; CHEMISTRY; CRYSTALLIZATION; GENETICS; KINETICS; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PHOSPHORYLATION; PHYSIOLOGY; PROTEIN CONFORMATION; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; BINDING SITES; CRYSTALLIZATION; DNA MUTATIONAL ANALYSIS; ENZYME ACTIVATION; G-PROTEIN-COUPLED RECEPTOR KINASES; KINETICS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PHOSPHORYLATION; PROTEIN CONFORMATION; PYRIMIDINE NUCLEOSIDES; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION;

EID: 77957778459     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2010.206     Document Type: Article

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