Activation of G protein-coupled receptor kinase 1 involves interactions between its N-terminal region and its kinase domain

Biochemistry

Volumn 50, Issue 11, 2011, Pages 1940-1949

  Huang, Chih Chin ^a   Orban, Tivadar ^c   Jastrzebska, Beata ^c   Palczewski, Krzysztof ^c   Tesmer, John J G ^a,b  

^a UNIVERSITY OF MICHIGAN   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOPHYSICAL PROPERTIES; CATALYTIC EFFICIENCIES; CROSS-LINKED PROTEINS; DISULFIDE BOND FORMATION; DISULFIDE BONDS; DOCKING SITES; G PROTEIN COUPLED RECEPTORS; G PROTEIN-COUPLED RECEPTOR KINASE; KINASE DOMAINS; N-TERMINALS; PEPTIDE PHOSPHORYLATION; SITE DIRECTED MUTAGENESIS; SPECIFIC BINDING; STRUCTURAL STUDIES; TRANSDUCIN;

AMINO ACIDS; COVALENT BONDS; MUTAGENESIS; PHOSPHORYLATION;

ENZYMES;

C PEPTIDE; G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR KINASE 2; G PROTEIN COUPLED RECEPTOR KINASE 3; G PROTEIN COUPLED RECEPTOR KINASE 4; G PROTEIN COUPLED RECEPTOR KINASE 5; G PROTEIN COUPLED RECEPTOR KINASE 6; RHODOPSIN KINASE; TRANSDUCIN;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; CATALYSIS; DISULFIDE BOND; ENZYME ACTIVATION; ENZYME STRUCTURE; PHOSPHORYLATION; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; BINDING SITES; G-PROTEIN-COUPLED RECEPTOR KINASE 1; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTATION; PROTEIN STRUCTURE, TERTIARY;

EID: 79952796822     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi101606e     Document Type: Article

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