Degradation of the G protein-coupled receptor kinase 2 by the proteasome pathway

Journal of Biological Chemistry

Volumn 273, Issue 52, 1998, Pages 35238-35244

  Penela, Petronila ^a   Ruiz Gómez, Ana ^a   Castaño, José G ^a   Mayor Jr , Federico ^a  

^a UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; BETA 2 ADRENERGIC RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; ISOPRENALINE; POLYCLONAL ANTIBODY; PROTEASOME; PROTEIN KINASE;

ARTICLE; CONTROLLED STUDY; EMBRYO; ENZYME DEGRADATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; INTERNALIZATION; KIDNEY CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RECEPTOR DOWN REGULATION; SIGNAL TRANSDUCTION;

BETA-ADRENERGIC RECEPTOR KINASE; CELL-FREE SYSTEM; CYCLIC AMP-DEPENDENT PROTEIN KINASES; CYSTEINE ENDOPEPTIDASES; ENDOCYTOSIS; ENZYME STABILITY; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GTP-BINDING PROTEINS; MULTIENZYME COMPLEXES; PEPTIDE FRAGMENTS; PROTEASOME ENDOPEPTIDASE COMPLEX; RECEPTORS, ADRENERGIC, BETA-2; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; UBIQUITINS;

EID: 0032567351     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.52.35238     Document Type: Article

References (16)

1. Böhm, S, K., Grady, E. F. & Bunnett, N. W. (1997) Biochem J. 322, 1-18
2. Lohse, M., Krasel, C., Winstel, R. & Mayor Jr., F. (1996) Kidney Int. 49, 1047-1052
3. Chuang T. T., Iacovelli, L., Sallese, M. & DeBlasi, A. (1996) Trends Pharmacol. Sci. 17, 416-421
4. Aragay, A. M., Ruiz-Gómez, A., Penela P., Samago, S., Elorza, A., Jimenez-Sainz, M. C. & Mayor Jr., F. (1998) FEES Lett. 430, 37-40
5. Ruiz-Gomez, A. & Mayor, F., Jr. (1997) J. Biol. Chem. 272, 9601-9604
6. Mayor, F., Penela, P. & Ruiz-Gómez, A. (1998) Trends Cardiovasc. Med. 8, 235-241
7. Ménard, L., Ferguson, S. S. G., Zhang, J. Lin, F. T., Lefkowitz, R. J., Caron, M. G. & Barak, L. S. (1997) Mol. Pharmacol. 51, 800-808
8. Daaka, Y., Luttrell, L. H., Ahn, S., Della Roca, G. J., Fergusson, S. S. G., Caron M. G. & Lefkowitz, R. J. (1998) J. Biol. Chem. 273, 685-688
9. Pitcher, J. A., Hall., R. A., Daaka, Y., Zhang, J., Ferguson, S. S. G., Hester, S., Miller, S., Caron, M. G., Lefkowitz, R. J. & Barak, L. S. (1998) J. Biol. Chem. 273, 12316-12324
10. Ungerer, M., Böhm, M., Elce, J. S., Erdmann, E. & Lohse, M. J. (1993) Circulation 78, 454-463
11. Gros, R., Benovic, J. L., Tan, C. M. & Feldman, R. D. (1997) J. Clin. Invest. 99, 2087-2093
12. Murga, C, Ruiz-Gómez, A., García-Higuera, I., Kim, C. M., Benovic, J. L. & Mayor, F., Jr. (1996) J. Biol. Chem. 271, 985-994
13. DebBurman, S. K., Ptasienski, J., Benovic, J. L. & Hosey, M. M. (1996) J. Biol. Chem. 271, 22552-22562
14. Murga, C., Esteban, N., Ruiz-Gómez, A. & Mayor, F. (1997) FEES Lett. 409, 24-28
15. Samama, P., Cotecchia, S., Costa, T. & Lefkowitz, R. J. (1993) J. Biol. Chem. 268, 4625-4636
16. Krappmann, D., Wulczyn, F. G. & Scheidereit, C. (1996) EMBO J. 15, 6716-6726