Cardiac-restricted expression of the carboxyl-terminal fragment of GRK3 uncovers distinct functions of GRK3 in regulation of cardiac contractility and growth: GRK3 Controls cardiac α1-adrenergic receptor responsiveness

Journal of Biological Chemistry

Volumn 283, Issue 16, 2008, Pages 10601-10610

  Vinge, Leif Erik ^a   Von Lueder, Thomas G ^a,b   Aasum, Ellen ^c   Qvigstad, Eirik ^d   Gravning, Jørgen A ^a   How, Ole Jakob ^c   Edvardsen, Thor ^a,b   Bjørnerheim, Reidar ^e   Ahmed, M Shakil ^a,b   Mikkelsen, Birthe W ^a   Øie, Erik ^b   Attramadal, Toril ^a   Skomedal, Tor ^d   Smiseth, Otto A ^a,b   Koch, Walter J ^f   Larsen, Terje S ^c   Attramadal, Håvard ^a,b  

^a UNIVERSITY OF OSLO   (Norway)

^b OSLO UNIVERSITY HOSPITAL   (Norway)

^c UNIVERSITY OF TROMSØ   (Norway)

^d UNIVERSITY OF OSLO   (Norway)

^e ULLEVÅL UNIVERSITY HOSPITAL   (Norway)

^f THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MEMBRANES; BLOOD PRESSURE; CELL MEMBRANES; MAMMALS; PROTEINS;

ADRENERGIC RECEPTORS; CARDIAC CONTRACTILITY; G PROTEIN COUPLED RECEPTORS; G PROTEIN-COUPLED RECEPTOR KINASE; LEFT VENTRICULAR FUNCTION; PLECKSTRIN HOMOLOGY DOMAINS; SIMULTANEOUS RECORDING; SYSTOLIC BLOOD PRESSURE;

HEART;

G PROTEIN COUPLED RECEPTOR KINASE 3; ISOPRENALINE; ADRBK2 PROTEIN, MOUSE; ALPHA 1 ADRENERGIC RECEPTOR;

ANIMAL TISSUE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; EX VIVO STUDY; HEART DEVELOPMENT; HEART FUNCTION; HEART LEFT VENTRICLE PRESSURE; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILITY; HEART MUSCLE RELAXATION; HEART RATE; HYPERTENSION; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; IN VIVO STUDY; MANOMETRY; MOUSE; NONHUMAN; PHENOTYPE; PLETHYSMOGRAPHY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SYSTOLIC BLOOD PRESSURE; TELEMETRY; TRANSGENIC MOUSE; ANIMAL; BIOLOGICAL MODEL; BLOOD PRESSURE; CELL CULTURE; GENE EXPRESSION REGULATION; HEART CONTRACTION; HEART MUSCLE; HEART VENTRICLE; MALE; METABOLISM; PATHOLOGY; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE;

MUS; MUS MUSCULUS;

ANIMALS; BLOOD PRESSURE; CELLS, CULTURED; G-PROTEIN-COUPLED RECEPTOR KINASE 3; GENE EXPRESSION REGULATION; HEART VENTRICLES; MALE; MICE; MICE, TRANSGENIC; MODELS, BIOLOGICAL; MYOCARDIAL CONTRACTION; MYOCARDIUM; PHENOTYPE; PLETHYSMOGRAPHY; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, ADRENERGIC, ALPHA-1;

EID: 44849086536     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M708912200     Document Type: Article

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