메뉴 건너뛰기




Volumn 63, Issue 2, 2014, Pages 369-375

Increased nitric oxide bioavailability in adult GRK2 hemizygous mice protects against angiotensin ii-induced hypertension

Author keywords

arteries; GRK2; hypertension; nitric oxide

Indexed keywords

ACETYLCHOLINE; ANGIOTENSIN II; ENDOTHELIAL NITRIC OXIDE SYNTHASE; G PROTEIN COUPLED RECEPTOR KINASE 2; ISOPRENALINE; NITRIC OXIDE; PHENYLEPHRINE;

EID: 84892909749     PISSN: 0194911X     EISSN: 15244563     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.113.01991     Document Type: Article
Times cited : (38)

References (18)
  • 1
    • 0037050009 scopus 로고    scopus 로고
    • Seven-transmembrane-spanning receptors and heart function
    • Rockman HA, Koch WJ, Lefkowitz RJ. Seven-transmembrane-spanning receptors and heart function. Nature. 2002;415:206-212.
    • (2002) Nature , vol.415 , pp. 206-212
    • Rockman, H.A.1    Koch, W.J.2    Lefkowitz, R.J.3
  • 3
    • 78049282918 scopus 로고    scopus 로고
    • Regulation of GPCR signaling in hypertension
    • Brinks HL, Eckhart AD. Regulation of GPCR signaling in hypertension. Biochim Biophys Acta. 2010;1802:1268-1275.
    • (2010) Biochim Biophys Acta , pp. 1268-1275
    • Brinks, H.L.1    Eckhart, A.D.2
  • 4
    • 29144497998 scopus 로고    scopus 로고
    • Mechanisms of regulation of G protein-coupled receptor kinases (GRKs) and cardiovascular disease
    • Penela P, Murga C, Ribas C, Tutor AS, Peregrín S, Mayor F Jr. Mechanisms of regulation of G protein-coupled receptor kinases (GRKs) and cardiovascular disease. Cardiovasc Res. 2006;69:46-56.
    • (2006) Cardiovasc Res , vol.69 , pp. 46-56
    • Penela, P.1    Murga, C.2    Ribas, C.3    Tutor, A.S.4    Peregrín, S.5    Mayor Jr., F.6
  • 5
    • 0033954751 scopus 로고    scopus 로고
    • G-Protein-coupled receptor kinase activity in hypertension: Increased vascular and lymphocyte G-protein receptor kinase-2 protein expression
    • Gros R, Chorazyczewski J, Meek MD, Benovic JL, Ferguson SS, Feldman RD. G-Protein-coupled receptor kinase activity in hypertension: increased vascular and lymphocyte G-protein receptor kinase-2 protein expression. Hypertension. 2000;35(1 Pt 1):38-42.
    • (2000) Hypertension , vol.35 , Issue.1 PART 1 , pp. 38-42
    • Gros, R.1    Chorazyczewski, J.2    Meek, M.D.3    Benovic, J.L.4    Ferguson, S.S.5    Feldman, R.D.6
  • 6
    • 67649842618 scopus 로고    scopus 로고
    • G protein-coupled receptor kinase 2 expression and activity are associated with blood pressure in black Americans
    • Cohn HI, Xi Y, Pesant S, Harris DM, Hyslop T, Falkner B, Eckhart AD. G protein-coupled receptor kinase 2 expression and activity are associated with blood pressure in black Americans. Hypertension. 2009;54:71-76.
    • (2009) Hypertension , vol.54 , pp. 71-76
    • Cohn, H.I.1    Xi, Y.2    Pesant, S.3    Harris, D.M.4    Hyslop, T.5    Falkner, B.6    Eckhart, A.D.7
  • 7
    • 74249083425 scopus 로고    scopus 로고
    • Endothelin signalling in arterial smooth muscle is tightly regulated by G protein-coupled receptor kinase 2
    • Morris GE, Nelson CP, Standen NB, Challiss RA, Willets JM. Endothelin signalling in arterial smooth muscle is tightly regulated by G protein-coupled receptor kinase 2. Cardiovasc Res. 2010;85:424-433.
    • (2010) Cardiovasc Res , vol.85 , pp. 424-433
    • Morris, G.E.1    Nelson, C.P.2    Standen, N.B.3    Challiss, R.A.4    Willets, J.M.5
  • 8
    • 0036209075 scopus 로고    scopus 로고
    • Vasculartargeted overexpression of G protein-coupled receptor kinase-2 in transgenic mice attenuates beta-adrenergic receptor signaling and increases resting blood pressure
    • Eckhart AD, Ozaki T, Tevaearai H, Rockman HA, Koch WJ. Vasculartargeted overexpression of G protein-coupled receptor kinase-2 in transgenic mice attenuates beta-adrenergic receptor signaling and increases resting blood pressure. Mol Pharmacol. 2002;61:749-758.
    • (2002) Mol Pharmacol , vol.61 , pp. 749-758
    • Eckhart, A.D.1    Ozaki, T.2    Tevaearai, H.3    Rockman, H.A.4    Koch, W.J.5
  • 10
    • 79961074094 scopus 로고    scopus 로고
    • G protein coupled receptor kinases as therapeutic targets in cardiovascular disease
    • Belmonte SL, Blaxall BC. G protein coupled receptor kinases as therapeutic targets in cardiovascular disease. Circ Res. 2011;109:309-319.
    • (2011) Circ Res , vol.109 , pp. 309-319
    • Belmonte, S.L.1    Blaxall, B.C.2
  • 11
    • 24744444714 scopus 로고    scopus 로고
    • A crucial role for GRK2 in regulation of endothelial cell nitric oxide synthase function in portal hypertension
    • Liu S, Premont RT, Kontos CD, Zhu S, Rockey DC. A crucial role for GRK2 in regulation of endothelial cell nitric oxide synthase function in portal hypertension. Nat Med. 2005;11:952-958.
    • (2005) Nat Med , vol.11 , pp. 952-958
    • Liu, S.1    Premont, R.T.2    Kontos, C.D.3    Zhu, S.4    Rockey, D.C.5
  • 13
    • 84862745056 scopus 로고    scopus 로고
    • Inhibitor of G protein-coupled receptor kinase 2 normalizes vascular endothelial function in type 2 diabetic mice by improving ?-arrestin 2 translocation and ameliorating Akt/eNOS signal dysfunction
    • Taguchi K, Matsumoto T, Kamata K, Kobayashi T. Inhibitor of G protein-coupled receptor kinase 2 normalizes vascular endothelial function in type 2 diabetic mice by improving ?-arrestin 2 translocation and ameliorating Akt/eNOS signal dysfunction. Endocrinology. 2012;153:2985-2996.
    • (2012) Endocrinology , vol.153 , pp. 2985-2996
    • Taguchi, K.1    Matsumoto, T.2    Kamata, K.3    Kobayashi, T.4
  • 14
    • 80055006025 scopus 로고    scopus 로고
    • Angiotensin II causes endothelial dysfunction via the GRK2/Akt/eNOS pathway in aortas from a murine type 2 diabetic model
    • Taguchi K, Kobayashi T, Takenouchi Y, Matsumoto T, Kamata K. Angiotensin II causes endothelial dysfunction via the GRK2/Akt/eNOS pathway in aortas from a murine type 2 diabetic model. Pharmacol Res. 2011;64:535-546.
    • (2011) Pharmacol Res , vol.64 , pp. 535-546
    • Taguchi, K.1    Kobayashi, T.2    Takenouchi, Y.3    Matsumoto, T.4    Kamata, K.5
  • 15
    • 76749162816 scopus 로고    scopus 로고
    • Role of extracellular matrix in vascular remodeling of hypertension
    • Briones AM, Arribas SM, Salaices M. Role of extracellular matrix in vascular remodeling of hypertension. Curr Opin Nephrol Hypertens. 2010;19:187-194.
    • (2010) Curr Opin Nephrol Hypertens , vol.19 , pp. 187-194
    • Briones, A.M.1    Arribas, S.M.2    Salaices, M.3
  • 18
    • 84876413668 scopus 로고    scopus 로고
    • Prodeath signaling of G protein-coupled receptor kinase 2 in cardiac myocytes after ischemic stress occurs via extracellular signal-regulated kinase-dependent heat shock protein 90-mediated mitochondrial targeting
    • Chen M, Sato PY, Chuprun JK, Peroutka RJ, Otis NJ, Ibetti J, Pan S, Sheu SS, Gao E, Koch WJ. Prodeath signaling of G protein-coupled receptor kinase 2 in cardiac myocytes after ischemic stress occurs via extracellular signal-regulated kinase-dependent heat shock protein 90-mediated mitochondrial targeting. Circ Res. 2013;112:1121-1134.
    • (2013) Circ Res , vol.112 , pp. 1121-1134
    • Chen, M.1    Sato, P.Y.2    Chuprun, J.K.3    Peroutka, R.J.4    Otis, N.J.5    Ibetti, J.6    Pan, S.7    Sheu, S.S.8    Gao, E.9    Koch, W.J.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.