Receptor-specific in vivo desensitization by the G protein-coupled receptor kinase-5 in transgenic mice

Proceedings of the National Academy of Sciences of the United States of America

Volumn 93, Issue 18, 1996, Pages 9954-9959

  Rockman, Howard A ^a   Choi, Dong J U ^a   Rahman, Nadeem U ^b,c   Akhter, Shahab A ^b   Lefkowitz, Robert J ^b,c   Koch, Walter J ^b  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

^c DUKE UNIVERSITY   (United States)

Author keywords

adrenergic receptor kinase; adenylylcyclase; angiotensin II receptor; myocardial contractility

Indexed keywords

ADENYLATE CYCLASE; ANGIOTENSIN 2 RECEPTOR; BETA ADRENERGIC RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; PROTEIN SERINE THREONINE KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; GENE EXPRESSION; HEART LEFT VENTRICLE ENDDIASTOLIC PRESSURE; HEART MUSCLE CONTRACTILITY; HEART RATE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RECEPTOR AFFINITY; RECEPTOR DOWN REGULATION; SECOND MESSENGER; TRANSGENIC MOUSE;

ANIMALS; BETA-ADRENERGIC RECEPTOR KINASE; CYCLIC AMP-DEPENDENT PROTEIN KINASES; GTP-BINDING PROTEINS; MICE; MICE, TRANSGENIC; MYOCARDIAL CONTRACTION; MYOCARDIUM; PHENOTYPE; PROTEIN-SERINE-THREONINE KINASES; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTORS, ADRENERGIC, BETA; RECEPTORS, ANGIOTENSIN; RNA, MESSENGER;

EID: 0029844311     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.93.18.9954     Document Type: Article

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