Lymphocyte Levels of GRK2 (βARK1) Mirror Changes in the LVAD-Supported Failing Human Heart: Lower GRK2 Associated With Improved β-Adrenergic Signaling After Mechanical Unloading

Journal of Cardiac Failure

Volumn 12, Issue 5, 2006, Pages 360-368

  Hata, Jonathan A ^a   Williams, Matthew L ^a   Schroder, Jacob N ^a   Lima, Brian ^a   Keys, Janelle R ^a   Blaxall, Burns C ^a   Petrofski, Jason A ^a   Jakoi, Andre ^a   Milano, Carmelo A ^a   Koch, Walter J ^b  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

Beta adrenergic receptor signaling; Biomarker; Cardiac transplantation; G protein coupled receptor kinases; Heart failure; Reverse remodeling

Indexed keywords

ADENYLATE CYCLASE; BETA ADRENERGIC RECEPTOR; BIOLOGICAL MARKER; G PROTEIN COUPLED RECEPTOR KINASE; G PROTEIN COUPLED RECEPTOR KINASE 2; G PROTEIN COUPLED RECEPTOR KINASE 5; MESSENGER RNA; RHODOPSIN; UNCLASSIFIED DRUG;

ARTICLE; BLOOD ANALYSIS; CELL LEVEL; CONTROLLED STUDY; ENZYME ACTIVITY; HEART ASSIST DEVICE; HEART FAILURE; HEART MUSCLE; HEART TRANSPLANTATION; HEART VENTRICLE REMODELING; HEART WORK; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOBLOTTING; IMPLANTATION; LEFT VENTRICLE ASSIST DEVICE; LYMPHOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RECEPTOR DENSITY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

ADULT; AGED; BETA-ADRENERGIC RECEPTOR KINASE; CARDIAC OUTPUT, LOW; FEMALE; HEART; HEART-ASSIST DEVICES; HUMANS; LYMPHOCYTES; MALE; MIDDLE AGED; MYOCARDIUM; RECEPTORS, ADRENERGIC, BETA; SIGNAL TRANSDUCTION;

EID: 33744533073     PISSN: 10719164     EISSN: 15328414     Source Type: Journal    
DOI: 10.1016/j.cardfail.2006.02.011     Document Type: Article

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