Uncovering G protein-coupled receptor kinase-5 as a histone deacetylase kinase in the nucleus of cardiomyocytes (Proceedings of the National Academy of Sciences of the United States of America (2008) 105, (12457-12462) DOI: 10.1073/pnas.0803153105);Uncovering G protein-coupled receptor kinase-5 as a histone deacetylase kinase in the nucleus of cardiomyocytes

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 34, 2008, Pages 12457-12462

  Martini, Jeffrey S ^a   Raake, Philip ^a   Vinge, Leif E ^a   DeGeorge Jr , Brent ^a   Chuprun, J Kurt ^a   Harris, David M ^a   Gao, Erhe ^a   Eckhart, Andrea D ^a   Pitcher, Julie A ^b   Koch, Walter J ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Cardiac hypertrophy; G protein signaling; Heart failure; Myocyte signaling

Indexed keywords

G PROTEIN COUPLED RECEPTOR KINASE 2; G PROTEIN COUPLED RECEPTOR KINASE 5; HISTONE DEACETYLASE; HISTONE DEACETYLASE KINASE 5; MUTANT PROTEIN; MYOCYTE ENHANCER FACTOR 2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL NUCLEUS; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENZYME ACTIVITY; GENETIC TRANSCRIPTION; HEART FAILURE; HEART MUSCLE; HEART MUSCLE CELL; HEART VENTRICLE HYPERTROPHY; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; TRANSGENIC MOUSE;

MUS; MUS MUSCULUS;

EID: 50449087071     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0808974105     Document Type: Erratum

References (33)

1. Premont RT, Gainetdinov RR (2007) Physiological roles of G protein-coupled receptor kinases and arrestins. Annu Rev Physiol 69:511-534.
2. Dzimiri N, Muiya P, Andres E, Al-Halees Z (2004) Differential functional expression of human myocardial G protein receptor kinases in left ventricular cardiac diseases. Eur J Pharmacol 489:167-177.
3. Rockman HA, Koch WJ, Lefkowitz RJ (2002) Seven-transmembrane-spanning receptors and heart function. Nature 415:206-212.
4. Rockman HA, et al. (1996) Receptor-specific in vivo desensitization by the G protein-coupled receptor kinase-5 in transgenic mice. Proc Natl Acad Sci USA 93:9954-9959.
5. Eckhart AD, et al. (2000) Hybrid transgenic mice reveal in vivo specificity of G protein-coupled receptor kinases in the heart. Circ Res 86:43-50.
6. Noma T, et al. (2007) Beta-arrestin-mediated beta1-adrenergic receptor transactivation of the EGFR confers cardioprotection. J Clin Invest 117:2445-2458.
7. Iaccarino G, Lefkowitz RJ, Koch WJ (1999) Myocardial G protein-coupled receptor kinases: Implications for heart failure therapy. Proc Assoc Am Physicians 111:399-405.
8. Johnson LR, Scott MG, Pitcher JA (2004) G protein-coupled receptor kinase 5 contains a DNA-binding nuclear localization sequence. Mol Cell Biol 24:10169-10179.
9. Yi XP, Gerdes AM, Li F (2002) Myocyte redistribution of GRK2 and GRK5 in hypertensive, heart-failure-prone rats. Hypertension 39:1058-1063.
10. Freeman JL, De La Cruz EM, Pollard TD, Lefkowitz RJ, Pitcher JA (1998) Regulation of G protein-coupled receptor kinase 5 (GRK5) by actin. J Biol Chem 273:20653-20657.
11. Pronin AN, Morris AJ, Surguchov A, Benovic JL (2000) Synucleins are a novel class of substrates for G protein-coupled receptor kinases. J Biol Chem 275:26515-26522.
12. Carman CV, Lisanti MP, Benovic JL (1999) Regulation of G protein-coupled receptor kinases by caveolin. J Biol Chem 274:8858-8864.
13. Carman CV, Som T, Kim CM, Benovic JL (1998) Binding and phosphorylation of tubulin by G protein-coupled receptor kinases. J Biol Chem 273:20308-20316.
14. Ribas C, et al. (2007) The G protein-coupled receptor kinase (GRK) interactome: Role of GRKs in GPCR regulation and signaling. Biochim Biophys Acta 1768:913-922.
15. Koch WJ, et al. (1995) Cardiac function in mice overexpressing the beta-adrenergic receptor kinase or a beta ARK inhibitor. Science 268:1350-1353.
16. McKinsey TA, Zhang CL, Olson EN (2001) Control of muscle development by dueling HATs and HDACs. Curr Opin Genet Dev 11:497-504.
17. Liu N, Olson EN (2006) Coactivator control of cardiovascular growth and remodeling. Curr Opin Cell Biol 18:715-722.
18. Dorn GW, 2nd, Force T (2005) Protein kinase cascades in the regulation of cardiac hypertrophy. J Clin Invest 115:527-537.
19. Akhter SA, et al. (1998) Targeting the receptor-Gq interface to inhibit in vivo pressure overload myocardial hypertrophy. Science 280:574-577.
20. McKinsey TA (2007) Derepression of pathological cardiac genes by members of the CaM kinase superfamily. Cardiovasc Res 73:667-677.
21. Backs J, Olson EN (2006) Control of cardiac growth by histone acetylation/deacetylation. Circ Res 98:15-24.
22. Adams JW, et al. (1998) Enhanced Galphaq signaling: A common pathway mediates cardiac hypertrophy and apoptotic heart failure. Proc Natl Acad Sci USA 95:10140-10145.
23. Gainetdinov RR, Premont RT, Caron MG, Lefkowitz RJ (2000) Reply: Receptor specificity of G-protein-coupled receptor kinases. Trends Pharmacol Sci 21:366-367.
24. Gainetdinov RR, et al. (1999) Muscarinic supersensitivity and impaired receptor desensitization in G protein-coupled receptor kinase 5-deficient mice. Neuron 24:1029-1036.
25. Zhang CL, et al. (2002) EN Class II histone deacetylases act as signal-responsive repressors of cardiac hypertrophy. Cell 110:479-488.
26. Chang S, et al. (2004) Histone deacetylases 5 and 9 govern responsiveness of the heart to a subset of stress signals and play redundant roles in heart development. Mol Cell Biol 24:8467-8476.
27. Penn RB, Pronin AN, Benovic JL (2000) Regulation of G protein-coupled receptor kinases. Trends Cardiovasc Med. 10:81-89.
28. Pronin AN, Benovic JL (1997) Regulation of the Gprotein-coupled receptor kinase GRK5 by protein kinase C. J Biol Chem 272:3806-3812.
29. Pronin AN, Satpaev DK, Slepak VZ, Benovic JL (1997) Regulation of G protein-coupled receptor kinases by calmodulin and localization of the calmodulin binding domain. J Biol Chem 272:18273-18280.
30. Pitcher JA, et al. (1996) Phosphatidylinositol 4,5-bisphosphate (PIP2)-enhanced G protein-coupled receptor kinase (GRK) activity. Location, structure, and regulation of the PIP2 binding site distinguishes the GRK subfamilies. J Biol Chem 271:24907-24913.
31. Kunapuli P, Gurevich VV, Benovic JL (1994) Phospholipid-stimulated autophosphorylation activates the G protein-coupled receptor kinase GRK5. J Biol Chem 269:10209-10212.
32. Jiang X, Benovic JL, Wedegaertner PB (2007) Plasma membrane and nuclear localization of G protein coupled receptor kinase 6A. Mol Biol Cell 18:2960-2969.
33. Pronin AN, Carman CV, Benovic JL (1998) Structure-function analysis of G protein-coupled receptor kinase-5. Role of the carboxyl terminus in kinase regulation. J Biol Chem 273:31510-31518.