Nuclear Translocation of Cardiac G Protein-Coupled Receptor Kinase 5 Downstream of Select Gq-Activating Hypertrophic Ligands Is a Calmodulin-Dependent Process

PLoS ONE

Volumn 8, Issue 3, 2013, Pages

  Gold, Jessica I ^a   Martini, Jeffrey S ^a   Hullmann, Jonathan ^a   Gao, Erhe ^b   Chuprun, J Kurt ^b   Lee, Linda ^c   Tilley, Douglas G ^b   Rabinowitz, Joseph E ^b   Bossuyt, Julie ^c   Bers, Donald M ^c   Koch, Walter J ^a,b  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN II; CALCIUM ION; CALMODULIN; ENDOTHELIN 1; G PROTEIN COUPLED RECEPTOR KINASE 5; GQ PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN; PHENYLEPHRINE; UNCLASSIFIED DRUG; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; LIGAND; PROTEIN BINDING;

ADULT ANIMAL; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BINDING SITE; CELL MEMBRANE; CELL NUCLEUS; CELLULAR DISTRIBUTION; CONTROLLED STUDY; HEART HYPERTROPHY; HEART MUSCLE CELL; IN VIVO STUDY; MOUSE; NEWBORN; NONHUMAN; PROTEIN DOMAIN; PROTEIN TRANSPORT; RABBIT; RAT; SARCOLEMMA; ACTIVE TRANSPORT; ADENOVIRIDAE; ANIMAL; GENE EXPRESSION REGULATION; HEART MUSCLE; HYPERTROPHY; MALE; METABOLISM; PROTEIN TERTIARY STRUCTURE; TRANSGENIC MOUSE;

ACTIVE TRANSPORT, CELL NUCLEUS; ADENOVIRIDAE; ANGIOTENSIN II; ANIMALS; CALMODULIN; CELL MEMBRANE; CELL NUCLEUS; G-PROTEIN-COUPLED RECEPTOR KINASE 5; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; HYPERTROPHY; LIGANDS; MALE; MICE; MICE, TRANSGENIC; MYOCARDIUM; PHENYLEPHRINE; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RABBITS; RATS;

EID: 84874607739     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0057324     Document Type: Article

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